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Blood Vessel

Blood vessels are tubular structures that transport blood throughout the body.
They include arteries, veins, and capillaries, which play vital roles in circulation, nutrient and oxygen delivery, and waste removal.
Researching blood vessel biology and function is crucial for understanding cardiovascular health and developing effective therapies for conditions like atherosclerosis, aneurysms, and vascular diseases.
PubCompare.ai's AI-driven platform can help optimize your blood vessel research by enhancing reproducibility, locating the best protocols and prducts from literature, and accelerating your discoveries with cutting-edge comparison tools.

Most cited protocols related to «Blood Vessel»

We used data on 9104 patients who were discharged alive following hospitalization with a diagnosis of acute myocardial infarction (AMI or heart attack) from 102 hospitals in Ontario, Canada, between April 1, 1999 and March 31, 2001. These data are similar to those reported on elsewhere [13 (link)–15 (link)], and were collected as part of the Enhanced Feedback for Effective Cardiac Treatment (EFFECT) Study, an initiative focused on improving the quality of care for cardiovascular disease patients in Ontario [16 ]. Data on patient demographics, presenting signs and symptoms, classic cardiac risk factors, comorbid conditions and vascular history, vital signs on admission, and results of laboratory tests, were abstracted directly from patients’ medical records. The exposure of interest was whether the patient was prescribed a statin at hospital discharge. Overall, 3049 (33.5 per cent) of patients received a prescription for a statin at discharge, while 6055 (66.5 per cent) did not receive a prescription at discharge. Table I compares the means of continuous baseline covariates and prevalences of dichotomous baseline covariates between treated and untreated subjects in the original unmatched sample. The prevalence of dichotomous variables was compared between treated and untreated subjects using a Chi-squared test, while a standard two-sample t-test was used to compare continuous baseline covariates.
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Publication 2009
Blood Vessel Cardiovascular Diseases Diagnosis Heart Hospitalization Hydroxymethylglutaryl-CoA Reductase Inhibitors Myocardial Infarction Patient Discharge Patients Quality of Health Care Signs, Vital
The Gene Expression Omnibus (GEO), the European Genome-phenome Archive (EGA) and The Cancer Genome Atlas (TCGA) repositories were screened for datasets with available survival data and at least 30 patients. Accessible transcriptomic data of 371 patients diagnosed with HCC were obtained from the TCGA (https://cancergenome.nih.gov/), with OS available for 364 patients [17 (link)]. Most patients were diagnosed at stage I and 67% were male. Patients with Asian and White/Caucasian ethnicity made up the majority, roughly in equal proportions. There was no significant difference in survival when comparing Asian and White/Caucasian patients (p = 0.32). Detailed description of the sample population is included in table 2.

Characterization of patient populations obtained from three independent transcriptomic datasets used in this study to validate biomarkers of overall survival and vascular invasion.

cohortRNA-seqIlluminaAffymetrix
sourceTCGAGSE20017GSE9843
platformIllumina HiSeq 2000Illumina HumanRef-8 WG-DASL v. 3.0Affymetrix HGU133 Plus 2.0 Array
total n37113591
gender
 males25010254
 females1213327
 NA10
stage
 stage I1719
 stage II8656
 stage III857
 stage IV58
 NA13511
race
 White/Caucasian18410272
 Black or African-American1743
 Asian158284
vascular invasion4045
death event1303223
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Publication 2018
Asian Persons Biological Markers Blood Vessel Ethnicity Europeans Gene Expression Gene Expression Profiling Genome Males Malignant Neoplasms Negroid Races Patients Population Group
Procedures for this longitudinal project have evolved over time. For the first 15 years of study, the inclusion criteria for this project (on enrollment) were: 1) age greater than 60 years; 2) absence of National Institute for Neurological and Communicative Disorders and Stroke–Alzheimer’s Disease and Related Disorders Association criteria for AD [11 (link)]; 3) absence of medical, neurological, and psychiatric conditions that affect cognition; 4) initial mental status examination scores above standard clinical cut points for dementia (e.g., Mini-Mental State Examination [12 (link)] MMSE> 24); 5) willingness to complete annual mental status examinations; and 6) brain donation at death (78% of donors also granted permission to remove other tissues). At enrollment, cerebrovascular disease (e.g., documented stroke or TIA) was exclusionary and even though treated hypertension was not exclusionary, overall vascular risks were low as reflected in their average (SD) modified Hachinski [13 (link)] score of 0.96 (±1.33; median=1.0). With the renewal of the ADC grant in 2000, annual neurological and medical examinations were initiated and the enrollment age was increased to age 70. Current participant enrollment inclusion and exclusion criteria are shown in (Table 2) and reflect the primary change in minimum age at enrollment.
Publication 2012
Blood Vessel Brain Death Cerebrovascular Accident Cerebrovascular Disorders Cognition Communicative Disorders Dementia Donors High Blood Pressures Mental Disorders Mini Mental State Examination Physical Examination Tissues Vaginal Diaphragm
All MRIs were assessed blinded to clinical information by one experienced neuroradiologist for the presence, location, and size of the recent symptomatic infarct and any other vascular lesions. A recent infarct was defined as a hyperintense area on DWI with corresponding reduced signal on the apparent diffusion coefficient image, with or without increased signal on FLAIR or T2-weighted imaging, that corresponded with a typical vascular territory.18 Recent small subcortical (lacunar) infarcts were defined as rounded or ovoid lesions with signal characteristics as above, >3- but <20-mm diameter, in the basal ganglia, internal capsule, centrum semiovale, or brainstem and carefully distinguished from WMH.1 (link) Cortical infarcts were defined as infarcts involving cortical ± adjacent subcortical tissue, or large (>2-cm) striatocapsular/subcortical lesions.14 (link) Lacunes were defined as rounded or ovoid lesions, >3- and <20-mm diameter, in the basal ganglia, internal capsule, centrum semiovale, or brainstem, of CSF signal intensity on T2 and FLAIR, generally with a hyperintense rim on FLAIR and no increased signal on DWI.14 (link) Microbleeds were defined as small (<5 mm), homogeneous, round foci of low signal intensity on gradient echo images in cerebellum, brainstem, basal ganglia, white matter, or cortico-subcortical junction, differentiated from vessel flow voids and mineral depositions in the globi pallidi.14 (link) Deep and periventricular WMH were both coded according to the Fazekas scale from 0 to 3.19 (link) We defined PVS as small (<3 mm) punctate (if perpendicular) and linear (if longitudinal to the plane of scan) hyperintensities on T2 images in the basal ganglia or centrum semiovale, and they were rated on a previously described, validated semiquantitative scale from 0 to 4.7 (link) Cerebral atrophy was classified for both deep (enlargement of the ventricles) and superficial (enlargement of the sulci) components on a 4-point scale (absent, mild, moderate, severe) in study 1, and on a modified 6-point version of the same scale in study 2.20 (link) The atrophy grade is determined by comparison with templates indicating normal to atrophied brains obtained in research into normal subjects on our scanner.20 (link) To merge the data from both studies, we condensed study 2's version to 4 categories (1 absent, 2–3 mild, 4 moderate, 5–6 severe). The intraclass correlation coefficient for WMH intraobserver rating (100 scans) was 0.96. The intrarater κ for PVS (50 scans) was 0.80 to 0.90 (unpublished data), for lacunes was 0.85 (unpublished data), and for microbleeds was 0.68 to 0.78.21 (link)
Publication 2014
Basal Ganglia Blood Vessel Brain Brain Stem Cerebellum Cortex, Cerebral Diffusion ECHO protocol Globus Pallidus Heart Ventricle Hypertrophy Infarction Infarction, Lacunar Internal Capsule Magnetic Resonance Imaging Minerals Radionuclide Imaging Tissues Urination White Matter
A special symposium on the classification of vascular cognitive disorders (VCD) was organized as part of the 4th Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VASCOG) in Singapore on 13 January, 2009. Experts in this field who attended that meeting reviewed the current evidence and critique the extant criteria. Based on the discussions, a draft proposal for a new set of criteria was drafted and reviewed by the group, including additional experts who had not attended the symposium. Multiple further drafts were similarly circulated after recommendations had been incorporated. The criteria were discussed at the 5th VASCOG conference in September 2011 in Lille, France and the 6th VASCOG conference in June 2013 in Toronto, Canada before being finalized.
Publication 2014
Blood Vessel Cognition Disorders Conferences

Most recents protocols related to «Blood Vessel»

Not available on PMC !

Example 13

IngredientsQty/vial
Melphalan50mg
PG5ml
Ethanol5ml
0.1N NaOH/0.1N HCLQS

NLT 80% of batch volume ethanol was transferred into a manufacturing vessel.

Propylene glycol was added to a vessel containing ethanol. Melphalan was added to the above mixture. Check the pH of the sample and if required adjust the pH to 3.5-5.5 using 0.1N NaOH/0.1N HCL. Final batch volume was made up using ethanol. The obtained solution was filtered and filled in vials followed by capping and sealing. The formulation was tested for stability at 2-8° C. for a period of 1 Month. Stability data is summarized 13A.

TABLE 13A
Stability at 1 Month1 Month
Purity99.48
Maximum Individual impurity0.1
Total Impurities0.52

Although the formulations, compositions, schemes and methods of the present disclosure have been described with reference to exemplary embodiments thereof, the present disclosure is not limited thereby. Indeed, the exemplary embodiments are implementations of the disclosed methods are provided for illustrative and non-limitative purposes. Changes, modifications, enhancements and/or refinements to the disclosed methods may be made without departing from the spirit or scope of the present disclosure. Accordingly, such changes, modifications, enhancements and/or refinements are encompassed within the scope of the present invention. All publications, patent applications, patents, figures and other references mentioned herein are expressly incorporated by reference in their entirety.

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Patent 2024
Blood Vessel Ethanol Melphalan Propylene Glycol

Example 2

In some applications, an infrasonic sensor is desired, with a frequency response fl that extends to an arbitrarily low frequency, such as a tenth of hundredth of a Hertz. Such a sensor might be useful for detecting fluid flows associated with movement of objects, acoustic impulses, and the like. Such an application works according to the same principles as the sonic sensor applications, though the length of individual runs of fibers might have to be greater.

In addition, the voltage response of the electrode output to movements is proportional to the velocity of the fiber, and therefore one would typically expect that the velocity of movement of fluid particles at infrasonic frequencies would low, leading to low output voltages. However, in some applications, the fluid movement is macroscopic, and therefore velocities may be appreciable. For example, in wake detection applications, the amplitude may be quite robust.

Generally, low frequency sound is detected by sensors which are sensitive to pressure such as infrasound microphones and microbarometers. As pressure is a scaler, multiple sensors should be used to identify the source location. Meanwhile, due to the long wave length of low frequency sound, multiple sensors have to be aligned far away to distinguish the pressure difference so as to identify the source location. As velocity is a vector, sensing sound flow can be beneficial to source localization. There is no available flow sensor that can detect infrasound flow in a broad frequency range with a flat frequency response currently. However, as discussed above, thin fibers can follow the medium (air, water) movement with high velocity transfer ratio (approximate to 1 when the fiber diameter is in the range of nanoscale), from zero Hertz to tens of thousands Hertz. If a fiber is thin enough, it can follow the medium (air, water) movement nearly exactly. This provides an approach to detect low frequency sound flow directly and effectively, with flat frequency response in a broad frequency range. This provides an approach to detect low frequency sound flow directly. The fiber motion due to the medium flow can be transduced by various principles such as electrodynamic sensing of the movement of a conductive fiber within a magnetic field, capacitive sensing, optical sensing and so on. Application example based on electromagnetic transduction is given. It can detect sound flow with flat frequency response in a broad frequency range.

For the infrasound detection, this can be used to detect manmade and natural events such as nuclear explosion, volcanic explosion, severe storm, chemical explosion. For the source localization and identification, the fiber flow sensor can be applied to form a ranging system and noise control to find and identify the low frequency source. For the low frequency flow sensing, this can also be used to detect air flow distribution in buildings and transportations such as airplanes, land vehicles, and seafaring vessels.

The infrasound pressure sensors are sensitive to various environmental parameters such as pressure, temperature, moisture. Limited by the diaphragm of the pressure sensor, there is resonance. The fiber flow sensor avoids the key mentioned disadvantages above. The advantages include, for example: Sensing sound flow has inherent benefit to applications which require direction information, such as source localization. The fiber flow sensor is much cheaper to manufacture than the sound pressure sensor. Mechanically, the fiber can follow the medium movement exactly in a broad frequency range, from infrasound to ultrasound. If the fiber movement is transduced to the electric signal proportionally, for example using electromagnetic transduction, the flow sensor will have a flat frequency response in a broad frequency range. As the flow sensor is not sensitive to the pressure, it has a large dynamic range. As the fiber motion is not sensitive to temperature, the sensor is robust to temperature variation. The fiber flow sensor is not sensitive to moisture. The size of the flow sensor is small (though parallel arrays of fibers may consume volume). The fiber flow sensor can respond to the infrasound instantly.

Note that a flow sensor is, or would be, sensitive to wind. The sensor may also respond to inertial perturbances. For example, the pressure in the space will be responsive to acceleration of the frame. This will cause bulk fluid flows of a compressible fluid (e.g., a gas), resulting in signal output due to motion of the sensor, even without external waves. This can be advantages and disadvantages depends on the detailed applications. For example, it can be used to detect flow distribution in the buildings. If used to detect infrasound, the wind influence be overcome by using an effective wind noise reduction approach.

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Patent 2024
Acceleration Acoustics A Fibers Blast Injuries Blood Vessel Cloning Vectors Dietary Fiber Electric Conductivity Electricity Electromagnetics Fibrosis Magnetic Fields Movement Pressure Reading Frames Sound Sound Waves Toxic Epidermal Necrolysis Ultrasonics Vaginal Diaphragm Vibration Water Movements Wind

Example 5

113 g of sodium metal was melted and brought to 250° C. in an Inconel reactor vessel. The sodium was then stirred using a Cowles blade mixer rotating at 2000-2500 rpm. Powdered hafnium chloride (from Areva) was pulse-fed over approximately 1 hour into the stirred sodium, until 82 g of hafnium chloride had been added, at which point the reaction was halted. At the end of the reaction, the vortex in the sodium had substantially disappeared and the reactor temperature had increased to 301° C.

Once the reaction was completed, the reactor vessel was sealed, transferred to a furnace, and heated to 825° C. for four hours to reduce the surface area of the hafnium metal produced in the reaction. During this process step, unreacted sodium was removed from the hafnium metal to leave a hafnium-sodium chloride composite.

The hafnium and sodium chloride mixture was then transferred to a vacuum furnace and heated under vacuum to 2300° C., held at that temperature for one hour, and then cooled. This removed the sodium chloride and produced a button of solid hafnium.

The hafnium button was analyzed via glow discharge mass spectrometry (GDMS) and found to have 26 ppm oxygen content, 1690 ppm zirconium, and less than 150 ppm total transition metals. The results demonstrate the production of a low oxygen hafnium metal produced directly from hafnium powder consolidation.

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Patent 2024
ARID1A protein, human Blood Vessel Hafnium hafnium chloride Mass Spectrometry Metals Oxygen Patient Discharge Powder Pulse Rate Sodium Sodium Chloride Transition Elements Vacuum Zirconium
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Example 8

Cyclohexene (1a) and polar organic solvent (as mentioned in Table 1) in (1:2 to 1:10 weight ratio with respect to the substrate) was taken in to a 60 ml vessel. Further, the hybrid photocatalyst was added and the resulting mixture was saturated with CO2 by purging at 1 atm pressure. The reaction vessel was sealed and irradiated with 20 W LED light (Model No. HP-FL-20 W-F, Hope LED Opto-Electric CO., Ltd) for 24 h. The conversion of the olefin and selectivity of the α,β-unsaturated hydroxyl or carbonyl compound as determined by GC-FID and GC-MS is mentioned in the Table 1 (entry 8-13).

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Patent 2024
Alkenes Blood Vessel cyclohexene Electricity Gas Chromatography-Mass Spectrometry Genetic Selection Hybrids Hydroxyl Radical Light Pressure Solvents
Not available on PMC !

Example 3

Cyclohexene (1a) and polar organic solvent, preferably acetonitrile in (1:2 to 1:10 weight ratio with respect to the substrate) was taken in to a 60 ml vessel. Further, the bare graphene oxide as photocatalyst (1 to 10 mol % of the substrate) was added and the resulting mixture was saturated with CO2 by purging at 1 atm pressure. The reaction vessel was sealed and irradiated with 20 W LED light (Model No. HP-FL-20 W-F, Hope LED Opto-Electric CO., Ltd) for 24 h. The intensity of the LED light at the reaction flask was measured to be 86 W/m2 by intensity meter. The conversion of the olefin was examined by GC-FID based on the unreacted substrate. The selectivity of the α,β-unsaturated hydroxyl or carbonyl compounds was determined by GC-MS. The conversion of olefin and the selectivity towards the corresponding α,β-unsaturated hydroxyl and ketone is given in the Table 1, entry 3.

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Patent 2024
acetonitrile Alkenes Blood Vessel cyclohexene cyclohexene oxide Electricity Gas Chromatography-Mass Spectrometry Genetic Selection Graphene graphene oxide Hydroxyl Radical Ketones Light Pressure Solvents

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More about "Blood Vessel"

Blood vessels are an integral part of the cardiovascular system, responsible for transporting vital fluids such as blood, oxygen, and nutrients throughout the body.
These tubular structures include arteries, veins, and capillaries, each playing a crucial role in circulation, tissue perfusion, and waste removal.
Researching blood vessel biology and function is paramount for understanding cardiovascular health and developing effective therapies for conditions like atherosclerosis, aneurysms, and vascular diseases.
The PubCompare.ai AI-driven platform can optimize your blood vessel research by enhancing reproducibility, locating the best protocols and products from literature, and accelerating your discoveries with cutting-edge comparison tools.
Leveraging techniques like FBS (Fetal Bovine Serum), MATLAB analysis, Matrigel culture, and DMEM (Dulbecco's Modified Eagle Medium) supplemented with Penicillin/Streptomycin, researchers can delve deeper into the complex mechanisms governing blood vessel formation, function, and pathological alterations.
The use of Prism 8 and Image-Pro Plus 6.0 software can further enhance data analysis and visualization, providing valuable insights into the behavior and dynamics of vascular structures.
Whether you are investigating angiogenesis, vascular remodeling, or the impact of pharmacological interventions, the PubCompare.ai platform can be your go-to resource for streamlining your blood vessel research, maximizing reproducibility, and accelerating your discoveries.
Explore the latest protocols, products, and techniques to advance your understanding of this crucial component of the cardiovascular system.