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Calcaneus

The calcaneus, also known as the heel bone, is a key component of the human foot.
It plays a crucial role in weight-bearing, balance, and locomotion.
Researchers studying the calcaneus can leverage PubCompare.ai to optimize their investigations.
This AI-powered tool helps identify the most accurate and reproducible research protocols from the literature, preprints, and patents.
By streamlining the research process, PubCompare.ai empowers researchers to make more informed decisions and advance the understanding of this important anatomical structure.

Most cited protocols related to «Calcaneus»

An ultrasound test was performed on 4 lower extremity muscles: rectus femoris (RF), biceps femoris (BF), tibialis anterior (TA), and medial gastrocnemius (MG) using a LOGIQ e ultrasound-imaging device (GE Healthcare UK Ltd., Chalfont, Buckinghamshire, England). The dominant leg was tested. Participants were examined while resting supine on an examining table. Ultrasound Brightness mode (B-mode) with musculoskeletal scanning preset and a multi-frequency linear transducer (8-12 MHz) with 12.7 × 47.1mm footprint were used. The beam width of the transducer was approximately 2.0mm at its narrowest point. Gain and transducer frequency were adjusted to 58-dB and 8 MHz, respectively. Scanning depth was set to 4 cm with an apparent spatial resolution of 80 μm/pixel. The scanning depth was only increased when testing participants with greater subcutaneous fat to allow for capturing enough muscle area. Time gain compensation was adjusted to neutral position. Focus number and area were increased to maximum and kept consistent across all participants to adjust for differences in muscle size among participants. Other ultrasound settings were unchanged from the preset.
Before starting the ultrasound study, the upper and lower leg length of each participant was measured from the superior lateral aspect of the patella to the anterior superior iliac spine and from the inferior lateral aspect of the patella to the calcaneus, respectively. Marks were made on the anterior and posterior parts of the 1/3 and 1/4 of upper and lower leg length, measured from the patella. The purpose of the marks was to ensure that the scanning locations between ultrasound and MRI as well as between participants were consistent. A generous amount of ultrasound gel was applied to avoid excessive pressure on the skin. Each scan involved a 16-second ultrasound clip on 1 of the marks, and each muscle was scanned twice (both 1/3 and 1/4 marks). A total of 8 scans were obtained from each participant. Each ultrasound clip was reviewed, and 1 frame with the best focus was chosen and saved into a JPEG image for analysis. Muscle EI was determined by gray-scale analysis using ImageJ16 . A muscle of interest was circled manually while avoiding surrounding fascia and bone. The mean voxel intensity of the selected muscle region was obtained from each measurement, and an average of 3 measurements was calculated. Subcutaneous fat thickness, muscle thickness, and area of the muscle of interest were also recorded. Images were analyzed by 2 investigators to test for the inter-rater reliability.
Publication 2015
Biceps Femoris Bones Calcaneus Clip Fascia Ilium Leg Lower Extremity Medical Devices Muscle, Gastrocnemius Muscle Tissue Patella Pressure Radionuclide Imaging Reading Frames Rectus Femoris Skin Subcutaneous Fat Tibial Muscle, Anterior Transducers Ultrasonics Vertebral Column
Samples of human Achilles tendons were obtained from the midportion Achilles tendon of healthy donors, defined as voluntary individuals having no history of Achilles tendon pain and demonstrating no structural changes on Colour Doppler ultrasound examination. The donors were all sports active on a recreational level. The ventral side of the tendon was exposed 3–4 cm from its calcaneal insertion through a small lateral skin incision, and the biopsy was taken with a sterile razor blade (Fig. 1). There were no complications as a result of the biopsy procedure.
Samples were washed with sterile Hanks' Balanced Salt Solution (HBSS; Invitrogen; 14170) and carefully dissected and minced using a sterile razor blade before they were enzymatically digested at 37°C, using collagenase (Clostridopeptidase A, C-0130 Sigma) diluted in D-MEM (Invitrogen; 11960) to obtain a concentration of 2 mg/ml. The digestion product was then centrifuged at 800 g for 5 min, the supernatant was discarded, and the pellet was re-suspended and cultured in D-MEM supplemented with 10% fetal bovine serum (FBS; Invitrogen; 16000), 1% pen-strep (Invitrogen; 15140) and 0.2% L-Glutamine (Invitrogen; 25030) at 37°C in a humidified atmosphere of 5% CO2 in air. The medium was changed every third day until confluence when cells were harvested using trypsin 0.05% with EDTA (Invitrogen; 25300), re-suspended in medium and seeded at a 1:3 ratio. Only cells from the third to sixth passage were used for experiments. Experiments were carried out in 1% FBS, if not otherwise stated, to limit the influence and unwanted effects of the serum. The serum-reduced/-starved cells still appeared healthy macroscopically, and the growing rate remained in a pattern of steady increase of the metabolic activity over several days, although the increase was clearly lower than in the 10% FBS conditions.
Publication 2011
Atmosphere Biopsy Calcaneus Cells Collagenase Digestion Donors Edetic Acid G-800 Glutamine Hanks Balanced Salt Solution Hemoglobin, Sickle Homo sapiens Pain Serum Skin Sterility, Reproductive Streptococcal Infections Tendon, Achilles Tendons Trypsin Ultrasounds, Doppler
During the period from 2006 to 2010, half a million British adults were recruited by the UK Biobank (“URLs”).30 (link) Subjects provided biological samples, consented to physical measurements and answered questionnaires relating to general health and lifestyle. Ethical approval was granted by the Northwest Multi-Centre Research Ethics Committee, and informed consent was obtained from all participants prior to participation. Heel bone quality was evaluated in 487,428 subjects by quantitative ultrasound speed of sound (SOS) and broadband ultrasound attenuation (BUA) using a Sahara Clinical Bone Sonometer (Hologic Corporation, Bedford, Massachusetts, USA). Further information regarding the assessment protocols are publicly available on the UK Biobank website (“URLs”). For in-depth details on participant selection, see the Supplementary Note. The R script used to curate the raw data is available on request, together with all supporting summary data and plots. Descriptive statistics of the cohort, after quality control, are detailed in Supplementary Table 1.
Fracture cases were identified using two mutually non-exclusive methods: Hospital Episodes Statistics linked through NHS Digital (“URLs”) with a hospital-based fracture diagnosis irrespective of mechanism within the primary (n=392,292) or secondary (n=320,448) diagnosis field, and questionnaire-based self-reported fracture within the past five years (n=501,694). We defined a set of International Classification of Diseases codes, 10th revision (ICD10), to separate fracture cases from controls with the Hospital Episodes Statistics data. We excluded fractures of the skull, face, hands and feet, pathological fractures due to malignancy, atypical femoral fractures, periprosthetic and healed fracture codes. A full list of ICD10 codes used can be found in Supplementary Table 22. We did not exclude any self-reported fracture cases by fracture site, since participants were only asked if they sustained a fracture at ankle, leg, hip, spine, write, arm, other or unknown. We identified 20,122 fractures using ICD10 codes and 48,818 using questionnaire-based self-reported data. Descriptive statistics of the cohort, after quality control and ancestry selection, are detailed in Supplementary Table 1.
For details on ancestry assignment of UK Biobank participants to White British and the identification of unrelated samples for LD reference estimation and X chromosome analyses, see the Supplementary Note and Supplementary Figures 20, 21 and 22.
Publication 2018
Adult Ankle Fracture Biopharmaceuticals Bones Calcaneus Diagnosis Ethics Committees, Research Face Femoral Fractures Fingers Foot Fracture, Bone Malignant Neoplasms Pathological Fracture Physical Examination Skull Fractures Sound Ultrasonics Vertebral Column X Chromosome
A QUS-II Calcaneal Ultrasonometer (Metra Biosystems, Mountain View, CA, USA) was used to measure bone density as broadband ultrasound attenuation (BUA) data. Ultrasound bone densiometry is reported to correlate well with the results of DXA and can predict osteoporosis-related fracture[11 (link),12 (link)] or detect bone fragility [13 (link)-15 (link)]. But there are many authors who question the precision of peripheral bone mineral density. Some authors reported that QUS parameters couldn't be used to predict osteopenia and that the sensitivities and specificities of QUS parameters were not high enough to be used as an alternative method of dual-energy x-ray absorptiometry (DXA) [16 (link)-19 (link)]. DXA is gold standard for measuring BMD is currently[15 (link),20 (link),21 (link)]. However, DXA scans are time-consuming, costly and expose the patient to radiation, which makes it a less-than-ideal method for a large population survey. On the contrary, a calcaneal ultrasonometer is timesaving, portable and suitable method for large surveys. For this reason, we chose to use it in this study.
Osteoporosis is defined by decreased bone mineral density (BMD) to a level of or less than -2.5 SD of the mean value of young adults. Firstly, our group assessed the precision of the quantitative ultrasound densitometry. Intra-test precision was calculated from three repeated scans with repositioning in 25 volunteers; the short-term coefficient of variation was 3.5% for BUA. T-scores used in our data were calculated from measured BUA data, the apparatus' specific threshold and further adjustment using data from Chinese patients living in Taiwan as reported by N.P. Yang[22 (link)]. Low bone mass was defined by a T-score of less than -1.0, and severe low bone mass was defined by a T-score of -2.5 or lower in this study. Weight and height data were also measured and collected.
Publication 2009
Bone Density Bones Calcaneus Chinese Densitometry Gold Osteopenia Osteoporosis Osteoporotic Fractures Patients Radiation Radionuclide Imaging Ultrasonography Voluntary Workers Young Adult
Participants wore spandex shorts, a form-fitting shirt, and their own exercise shoes. Forty-two spherical, retro-reflective markers (14mm diameter) were placed, bilaterally, on the lower extremity, pelvis, and trunk (Fig 1). Specifically, markers were placed over the following landmarks: acromion processes, xiphoid process, spinous process of the seventh cervical vertebra (C7), superior aspects of the iliac crests, anterior superior iliac spines, sacrum (midpoint between the posterior superior iliac spines), greater trochanters, lateral and medial femoral epicondyles, lateral and medial malleoli, posterior aspect of the calcanei, and first and fifth metatarsal heads. Plastic shells that contained four, non-collinear markers each were positioned laterally over the thigh and shank [39 (link)]. Marker shells were attached to the lower extremity segments via neoprene wraps and hook and loops fasteners. Once the markers were placed over the appropriate anatomical landmark, a static calibration trial was recorded. Following the static trial, the medial knee and ankle markers were removed so they would not encumber participants during the movement trials.
Marker motion was recorded using motion capture system (Nexus, Vicon Motion Systems Ltd, Centennial, CO) with ten Vicon MX-T20 cameras sampling at 100 Hz. Each camera was calibrated to have less than 0.15 mm residual error. Participants performed three different single leg weight bearing tasks (Fig 2) in the following order: step down from a 16 cm step (SD16), step down from a 24 cm step (SD24), and single leg squat (SLS). Order was not randomized as this was part of a larger clinical study. For each trial of each task, the starting and ending position was standing on both legs with feet in a self-selected position. For the step down tasks, participants stood with both feet on top of a wooden box. From the starting position, they were instructed to stand on one leg, lower the non-stance limb until the heel lightly touched the floor and then return to standing with both feet on the box. For the single leg squat task, participants were instructed shift their weight onto one leg, squat as low as possible with their non-stance limb extended anteriorly, and return to standing on both legs. The position of the non-stance limb was selected to be similar to the step down task. Participants had an opportunity to practice each task. Participants were given approximately 10 seconds between each single trial of each task, and approximately two to three minutes between tasks. The same leg was always tested first. A metronome set at 60 beats per minute was used to help standardize movement speed. Participants were instructed to try to move “down on a beat and up on a beat.” Participants were given feedback to help maintain a consistent movement speed for each individual trial; however, strict adherence to the metronome was not enforced. Upper extremities had to be maintained either at their sides or out to the side. Trials in which subjects lost their balance or used their upper extremities for support on the surrounding bars were recollected. Five trials were collected on each lower extremity for each task. Only the data during right stance was analyzed for this study.
Publication 2015
Acromion Anatomic Landmarks Ankle Calcaneus Cervical Vertebrae Femur Foot Head Heel Iliac Crest Ilium Knee Lower Extremity Metatarsal Bones Movement Neoplasm Metastasis Neoprene Nexus Pelvis Sacrum Spandex Spinous Processes Thigh Trochanters, Greater Upper Extremity Vertebral Column Xiphoid Bone

Most recents protocols related to «Calcaneus»

Clinical assessments and analyses were performed on the patients. The American Orthopedic Foot and Ankle Society (AOFAS), Visual Analogue score (VAS), and SF-12 [21 (link)] were used to evaluate the function before the operation and at the last follow-up. The mental component score (MCS) and physical component score (PCS) were calculated using the SF-12 based on the Ware et al. Manual [22 (link)]. The final follow-up visits were performed from August to December 2022.
The foot was examined radiologically in the weight-bearing AP and lateral view. Calcaneal pitch angle, lateral Meary's angle, AP Meary's angle, AP talocalcaneal angle, and talonavicular coverage were measured twice by two different senior doctors at each visit (preoperative, three months after the operation and final follow-up). A successful fusion was defined as a painless foot during weight-bearing and trabeculation across the fusion line on radiography. These parameters measured on the weight-bearing AP and lateral views of the foot are shown in Fig. 2.

Measurement parameters on weight-bearing AP and lateral views. A The calcaneal pitch angle. B The lateral Meary's angle (positive sign = dorsal intersection; negative sign = plantar intersection). C Ap Meary's angle (positive sign = first metatarsal abduction; negative sign = adduction). D Ap talocalcaneal angle. E The talonavicular coverage (positive sign = navicular bone in valgus; negative sign = navicular bone in varus)

Publication 2023
Ankle Calcaneus Foot Metatarsal Bones Navicular Bone of Foot Patients Physical Examination Physicians X-Rays, Diagnostic
The UK Biobank is a cohort comprising ∼500,000 individuals recruited through the NHS registry at age 40–69 from across the UK. Individuals were were not selected on the basis of having disease, resulting in a broad cross-section of the UK population. For all participants, a number of baseline physical measurements were taken and an extensive questionnaire completed comprising information on lifestyle, demographic and socioeconomic factors. Additionally, blood and urine samples were collected and further tests including a heel-bone ultrasound, bio-impedance, hand-grip strength, spirometry, blood pressure and several cognitive tests were performed. Each individual was further genotyped and exome sequenced. The participants also agreed to ongoing linkage of their medical records [10 (link)].
Publication 2023
BLOOD Blood Pressure Calcaneus Cognitive Testing Exome Physical Examination Spirometry Ultrasonics Urine
The general characteristics of the enrolled subjects included age, sex, and flexible flatfoot conditions. Both lateral foot radiographs of the children at the time of diagnosis and at the end of treatment were taken to evaluate the effects of foot insole application in a barefoot standing position. Foot lateral radiography was used for radiographic measurement. The bilateral calcaneal pitch angle (CPA) and Meary’s angle, known as the talo first metatarsal angle (TMA), were measured in both feet. CPA is defined as the angle between the calcaneus and inferior aspect of the foot. TMA is defined as the angle between the line of the longitudinally bisected talus and the longitudinal axis of the 1st metatarsal bone (Fig. 2). Both radiologic indices calculated through foot lateral radiography in a standing position are usually used clinically as criteria for flexible flatfoot: CPA < 15’; TMA > 3’.[14 (link)] Both indices were periodically followed up within 3 to 4 months after the beginning of the foot insole prescription. The process of radiologic evaluation with adjustment of the foot insole was terminated at the point of loss of the associated symptoms, as mentioned above. All the radiographic parameters were measured by a trained physiatrist.
The foot insole was also adjusted periodically for 3 to 4 months after confirmation of the follow up radiograph. The device was custom-made using ethylene vinyl acetate with foam materials. This supported the medial longitudinal arch (Fig. 3). During the intervention, the foot insole was revised according to the height of the pad.
Publication 2023
Calcaneus Child Diagnosis Epistropheus ethylene Exhaling Foot Medical Devices Metatarsal Bones Physiatrists Process Assessment, Health Care Talipes Calcaneovalgus Talus vinyl acetate X-Rays, Diagnostic
The incision of the entry point was made longitudinally, from 3 to 5 cm, and
aligned with the tibial axis in the sagittal plane. Depending on the brand, the
retrograde intramedullary nail (RIMN) could be straight or have a valgus
angulation. If the RIMN is straight, we aligned the incision with the coronal
plane’s tibial axis. In the case of an RIMN with valgus angulation, the incision
is made laterally to the tibial axis in the coronal plane. The entry point in
the sagittal plane was collinear with the tibial axis and, depending on the RIMN
model used, was also in the coronal plane.
After passing the guide wire, the channel was milled to a diameter 1.0 to 1.5 mm
larger than the RIMN, and we introduced it. Maintaining the parameters of
dorsiflexion and external rotation, the RIMN was locked with one distal
posteroanterior screw in the calcaneus, another in the talus, and one proximal
screw.
At the end of the procedure, we performed hemostasis, cleaning, placement of the
vacuum drain, layered suture, dressing, and analgesic short-leg splint (Figure 1).
Publication 2023
Analgesics Calcaneus Epistropheus Hemostasis Intramedullary Nailing Splints Sutures Talus Tibia
The definitive stabilization began with the fixation of cannulated screws with
partial thread 7.0 with a lag function. One screw was from the posterior region
of the calcaneus to the body of the talus, and another was from the
posterolateral region of the tibia to the anteromedial talus. Another option was
using a single 7.0-mm screw entering the posterior and plantar region of the
calcaneus toward the anterior tibia, compressing both joints.
We placed a plate on the lateral side for the neutralization function. The plate
used was a 4.5-mm locking compression plate of the proximal humerus put in
reverse. There were 3 bicortical screws in the tibia and 4 distributed between
the calcaneus and talus (Figure 2).
Publication 2023
Calcaneus Human Body Humerus Joints Talus Tibia

Top products related to «Calcaneus»

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The Sahara Clinical Bone Sonometer is a medical device designed for the assessment of bone density. It utilizes ultrasound technology to measure the bone mineral content and structure, providing information about the overall bone health of the patient.
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MATLAB is a high-performance programming language and numerical computing environment used for scientific and engineering calculations, data analysis, and visualization. It provides a comprehensive set of tools for solving complex mathematical and computational problems.
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Visual3D is a software application developed by C-Motion for analyzing and visualizing motion capture data. It provides a comprehensive set of tools for processing and interpreting three-dimensional movement data obtained from various motion capture systems.
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Achilles InSight is a laboratory equipment product from GE Healthcare. It is designed for bone density measurement and evaluation. The device utilizes ultrasound technology to assess bone health parameters.
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The Achilles EXP II is a portable ultrasound device designed for bone densitometry measurements. It utilizes quantitative ultrasound technology to assess bone mineral density, providing information about bone health and fracture risk.
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The Skyscan 1172 is a high-resolution desktop micro-CT scanner designed for non-destructive 3D imaging and analysis of a wide range of small samples. It provides high-quality X-ray imaging and data processing capabilities for various applications.
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The Lunar Achilles Insight is a bone densitometry system designed to measure bone mineral density (BMD) and assess osteoporosis risk. The device uses ultrasound technology to evaluate the bone status of patients.
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CTAn software is a tool for the analysis and visualization of 3D data from micro-computed tomography (micro-CT) imaging. It provides core functions for image processing, analysis, and quantification of various morphological parameters.
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The SkyScan 1176 is a high-resolution in vivo micro-CT scanner designed for small animal imaging. It provides fast, high-quality 3D imaging of small samples, including small animals, plant specimens, and materials.
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Force plates are scientific instruments designed to measure the forces exerted by an object or person on the ground. They are used to capture the magnitude and direction of the forces applied during various activities, such as walking, running, or jumping. Force plates provide precise data on ground reaction forces, which can be used for biomechanical analysis and research purposes.

More about "Calcaneus"

The calcaneus, also known as the heel bone, is a crucial component of the human foot.
It plays a vital role in weight-bearing, balance, and locomotion.
Researchers studying the calcaneus can leverage advanced tools like PubCompare.ai to optimize their investigations.
PubCompare.ai is an AI-powered tool that helps identify the most accurate and reproducible research protocols from the literature, preprints, and patents.
By streamlining the research process, this innovative platform empowers researchers to make more informed decisions and advance the understanding of this important anatomical structure.
In addition to PubCompare.ai, researchers can utilize other cutting-edge technologies like the Sahara Clinical Bone Sonometer, MATLAB, Visual3D, Achilles InSight, Achilles EXP II, Skyscan 1172, Lunar Achilles Insight, CTAn software, and SkyScan 1176 to study the calcaneus in depth.
These tools provide valuable insights into the structure, function, and biomechanics of the heel bone, enabling researchers to uncover new discoveries and develop improved diagnostic and treatment methods.
By combining the power of AI-driven protocol comparison with these advanced technologies, researchers can streamline their investigations, optimize their research protocols, and advance the scientific understanding of the calcaneus and its role in human health and mobility.
Whether you're studying the biomechanics of the foot, the effects of injury or disease on the calcaneus, or exploring new imaging techniques, these tools can help you navigate the research landscape more effectively and produce more reliable, reproducible results.