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Septums, Nasal

Septums and the nasal region are critical components of the respiratory system, playing vital roles in airflow, olfaction, and overall nasal function.
This MeSH term encompasses the anatomy, physiology, and pathology of the nasal septum, nasal cavity, and surrounding nasal structures.
Researchers can leverage PubCompare.ai's advanced AI tools to streamline nasal and septum-related studies, identifying the most effective protocols and methods from literature, preprints, and patents with enhanced reproducibility and accuracy.
Optimize your sepetal and nasal research today for better science tomorrow.

Most cited protocols related to «Septums, Nasal»

1
Evaluating Nasal Septal Deviation: SNOT-22 Assessment
Cited 8 times
A group of patients with nasal septal deviation candidate for septoplasty were enrolled in the study. The study was conducted from March to June 2012 in a tertiary ENT center in Tehran, Iran. Only adults older than 18 years old were included. The diagnosis of nasal septal deviation was made by otorhinolaryngologist based on clinical examination, anterior rhinoscopy, and coronal CT scans. A group of healthy volunteers were also included. They were adults with no history of chronic sinonasal disease. They were not taking any medication related to sinonasal problems. The people in this group were selected from the family members of the patients or personnel of the center. Both groups answered the final draft of the Persian version of SNOT 22. All participants in both groups were asked to answer the questionnaire again in a two-week period. The patients group re-answered the questionnaire before any surgical intervention.
Jalessi M., Farhadi M., Kamrava S.K., Amintehran E., Asghari A., Rezaei Hemami M., Mobasseri A, & Masroorchehr M. (2013). The Reliability and Validity of the Persian Version of Sinonasal Outcome Test 22 (Snot 22) Questionnaires. Iranian Red Crescent Medical Journal, 15(5), 404-408.
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Publication 2013
Adult Diagnosis Disease, Chronic Family Member Healthy Volunteers Operative Surgical Procedures Patients Pharmaceutical Preparations Physical Examination Septums, Nasal X-Ray Computed Tomography
2
Bovine Proteoglycan Arthritis Induction
Cited 7 times
As previously described [23 (link)], with minor modifications, a dose (100 μL) containing 100 μg of bovine proteoglycan extracted from nasal septum (Sigma Aldrich, St. Louis, MO, USA) and 1 mg of emulsified (micelle form) dodecyl dioctadecyl ammonium bromide (DDA) adjuvant (Sigma Aldrich, St. Louis, MO, USA) was intraperitoneally injected three times with 21-day interval for arthritis induction. After the third injection, arthritis score was daily evaluated until euthanasia (70 days after the first immunization). Arthritis severity was determined using a standard visual scoring system based on the degree of swelling and redness ranging from 0 to 4 for each paw. The following system was used: 0 = normal; 1 = mild swelling in the paw or one joint; 2 = moderate swelling and redness in the paw and one or more joints; 3 = pronounced swelling and redness in the paw, all joints, and ankle; 4 = severe swelling and redness of the entire paw and ankle and movement limitation. This classification resulted in a total score that ranged from 0 to 16 for each animal.
Ishikawa L.L., Colavite P.M., da Rosa L.C., Balbino B., França T.G., Zorzella-Pezavento S.F., Chiuso-Minicucci F, & Sartori A. (2014). Commercial Bovine Proteoglycan Is Highly Arthritogenic and Can Be Used as an Alternative Antigen Source for PGIA Model. BioMed Research International, 2014, 148594.
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Publication 2014
ammonium bromide Animals Arthritis Cattle Erythema Euthanasia Joints Joints, Ankle Micelles Movement Pharmaceutical Adjuvants Proteoglycan Septums, Nasal Vaccination
3
Evaluating Arabic SFAR in Allergic Rhinitis
Cited 5 times
The study protocol was approved by the Research Center of Medical College of King Saud University and its Ethical Committee, and all participants provided informed consent. Individuals with poor Arabic reading and writing abilities, or with a non-Arabic mother language, were excluded from this study. This cross-sectional study evaluated 75 control participants and 173 patients with AR, who were recruited from the primary healthcare clinic at King Abdul-Aziz University Hospital in Riyadh during August–November 2016. All patients with AR had signs and symptoms that were confirmed by our otolaryngologists. The controls were healthy individuals who had accompanied the patients to the otolaryngology clinic, but were found to not have AR signs/symptoms by our otolaryngologists. All investigators were otolaryngologist specialists or consultants who were blinded to the purpose of the study.
Before the clinic visit, potential participants were asked to sign the consent form and then complete the Arabic SFAR. The completed questionnaires were placed in sealed envelopes and given to the clinic nurses in order to blind the physicians to the responses. All participants were assessed by our otolaryngologists to document their history, including presence or absence of AR symptoms (sneezing, nasal congestion, watery rhinorrhea, postnasal drip, nasal itching, anosmia/hyposmia, headache, tearing, red eyes, fatigue, and malaise), and completed a physical examination to document AR signs (allergic shiners, nasal crease, swollen nasal mucosa, pale, bluish-gray color, watery nasal discharge, and nasal septum deviation or perforation).
Alharethy S., Al Wedami M., Syouri F., Alqabbani A.A., Baqays A., Mesallam T, & Aldrees T. (2017). Validation of the Arabic version of the score for allergic rhinitis tool. Annals of Saudi Medicine, 37(5), 357-361.
Publication 2017
Blindness Clinic Visits Eye Fatigue Headache Hyposmia Mothers Nasal Mucosa Nose Nurses Otolaryngologist Patients Physical Examination Physicians Primary Health Care Rhinorrhea Septums, Nasal Shiner Signs and Symptoms Specialists
4
Acupuncture Effects on Alzheimer's Disease
Cited 5 times
Mice in N group received no treatment, but were grabbed and bound when mice in other groups were receiving treatments to ensure an equivalent condition. Mice in AD group were treated in accordance with N group. Donepezil hydrochloride tablets were crushed and dissolved in distilled water, with the dose at 0.92 mg/kg and delivered to mice by oral administration in M group, which were grabbed and bound as N and AD group.
Mice in EA group received EA treatment. The acupoints Baihui (GV20), Yintang (GV29) and Shuigou (GV26) in GV were chosen according to document (Li, 2007 ; Guo and Fang, 2012 ). Acupoints location in mouse were well-correspond to the anatomical site of human acupoints, GV20 is at the midpoint between the auricular apices, GV29 is located midway between the medial ends of the two eyebrows, while GV26 is located below the mouse nasal septum, at the junction of the lower two thirds and upper one third of the cleft lip midline (Figure 1). Sterile acupuncture needles were separately inserted with downward horizontal at GV20 and upward horizontal at GV29, 0.5 cm in depth. Then needles were connected to a programmed apparatus, and stimulated with sparse waves (2 Hz in frequency, 2 V in voltage, and 0.1 mA in electric current) generated from EA apparatus, which would be the most preferable if slight trembling of animal’s head was observed. Vertical pricking at GV26 acupoint was manipulated at the end of EA treatment. All treatment approaches should be implemented for 20 min, once a day for 15 consecutive days.
Cao J., Tang Y., Li Y., Gao K., Shi X, & Li Z. (2017). Behavioral Changes and Hippocampus Glucose Metabolism in APP/PS1 Transgenic Mice via Electro-acupuncture at Governor Vessel Acupoints. Frontiers in Aging Neuroscience, 9, 5.
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Publication 2017
Acupuncture Points Administration, Oral Animals Body Regions Donepezil Hydrochloride Electricity Eyebrows Head Homo sapiens Lips, Cleft Mice, House Needles Septums, Nasal Sterility, Reproductive Therapy, Acupuncture
5
Quantification of Olfactory Neuron Markers
Cited 4 times
As previously described (Ueha et al., 2014 (link), 2016a (link)), all samples were cut at the level of the anterior end of the olfactory bulb. Four-micrometer thick paraffin sections were deparaffinized in xylene and rehydrated in ethanol before immunostaining. For immunostaining, deparaffinized sections were treated with 3% hydrogen peroxide to block endogenous peroxidase activity and were incubated in Blocking One (Nacalai Tesque, Kyoto, Japan) to block non-specific immunoglobulin binding. Primary antibodies were detected using peroxidase-conjugated secondary antibodies and a diaminobenzidine (DAB) substrate. Three different microscope fields (dorsal, middle and ventral) of each bilateral septal OE were captured using a digital microscope camera (Keyence, Osaka, Japan, BZ-9000) with a 40× objective lens (Figure 1B). Analyses were restricted to the OE of the nasal septum to minimize variation between specimens (Figure 1C). The numbers of olfactory marker protein-positive (OMP+) ORNs was quantified by averaging the number of cells in each of the three microscopic fields between sections. The number of SOX2+ ORN progenitors, GAP43+ immature ORNs, Ki67+ cells, and cleaved Cas3+ apoptotic cells per mm of basal layer length were manually counted using digital imaging software (Photoshop CS6 Adobe, San Jose, CA, USA), in a blinded manner for each of the three different fields.
Ueha R., Ueha S., Kondo K., Kikuta S, & Yamasoba T. (2018). Cigarette Smoke-Induced Cell Death Causes Persistent Olfactory Dysfunction in Aged Mice. Frontiers in Aging Neuroscience, 10, 183.
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Publication 2018
Antibodies Apoptosis Cardiac Arrest Cells Ethanol Fingers Immunoglobulins Lens, Crystalline Microscopy Olfactory Bulb Olfactory Marker Protein Paraffin Peroxidase Peroxide, Hydrogen Septums, Nasal SOX2 protein, human Xylene

Most recents protocols related to «Septums, Nasal»

1
Quantifying Bacterial Adhesion to Nasal Cells

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Publication 2023
Buffers Dialysis Epithelial Cells Flow Cytometry Fluorescein Fluorescein-5-isothiocyanate Healthy Volunteers Homo sapiens isothiocyanate Nose prisma Proteins Septums, Nasal Sodium Chloride Stains Synapsin I Tromethamine
2
Endonasal Craniopharyngioma Resection
The surgery was performed at The Ohio State University Wexner Medical Center, Columbus, OH, United States. In the video, the authors demonstrate the endonasal nasal septal flap preparation, the extended sellar craniotomy (with resection of the sphenoid planum and the floor of the anterior fossa), the anatomic landmarks that guide bone drilling and dural opening, the aspect of the intraoperative real time ultrasound (demonstrating the craniopharyngioma, the stalk and the anterior pituitary gland), tumor resection and dissection from the surrounding structures, and the vasculo-nervous structures that must be preserved in order to diminish morbidity and mortality.
The intraoperative endonasal US was performed using the BK Medical Bk 5,000 Ultrasound System with the N20P6 Minimally Invasive 6 × 7 mm Transducer.
The images from the surgery and the ultrasound were gathered and edited using a video editing software.
Finger G., Wu K.C., Godil S.S., Carrau R.L., Hardesty D, & Prevedello D.M. (2023). Ultrasound-guided endoscopic endonasal resection of sellar and suprasellar craniopharyngiomas. Frontiers in Surgery, 10, 1073736.
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Publication 2023
Bones Craniopharyngioma Craniotomy Dissection Neoplasms Nervousness Operative Surgical Procedures Pituitary Gland, Anterior Planum Septums, Nasal Sphenoid Bone Stalking Surgical Flaps Transducers Ultrasonics Ultrasonography
3
Isolation and Expansion of Nasal and Intervertebral Disc Cells
Tissues were collected following local ethical committee approval (EKNZ-2015305, University Hospital Basel). After obtaining informed consent from all donors, human nasal septal cartilage tissue was harvested from the patients undergoing rhinoplasty (total n = 6, Supplmentary Table S1). NP tissue was acquired from donors undergoing surgery for DDD. Harvested NP tissues were graded using Pfirrmann scale (Urrutia et al., 2016 (link)). NP tissues with Pfirrmann grade 2–3 (mild/moderate degeneration) were used in this study (total n = 6, Supplementary Table S2). NC and NP cells were isolated after digestion in collagenase type II (0.15% for NC; 0.05% for NP cells for 22 h), and expanded in NC and NP expansion medium respectively (composition in Supplementary Material) up to passage 3.
Kasamkattil J., Gryadunova A., Schmid R., Gay-Dujak M.H., Dasen B., Hilpert M., Pelttari K., Martin I., Schären S., Barbero A., Krupkova O, & Mehrkens A. (2023). Human 3D nucleus pulposus microtissue model to evaluate the potential of pre-conditioned nasal chondrocytes for the repair of degenerated intervertebral disc. Frontiers in Bioengineering and Biotechnology, 11, 1119009.
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Publication 2023
Cartilage Cells Collagenase Digestion Donors Homo sapiens Operative Surgical Procedures Patients Rhinoplasty Septums, Nasal Tissues
4
Murine Intranasal and Subcutaneous Vaccine Evaluation
Female Balb/c mice (6-8 weeks) were divided of 3-4 mice for each group: control group, Squ/OVA, Spo-Squ/OVA, each of the above groups was administered intranasally at a dose of 25 μL free OVA(1 μg/μL) or OVA adjuvant(1:1) for one mouse; the other Squ/OVA subcutaneously at a dose of 25 μL for one mouse. Control group was PBS administered without vaccine.
The mice were immunized twice, once every two weeks. Blood samples were obtained from the retro-orbital plexus at day 28 after immunization. The blood could stand for 1 h after the clot was fully clotted. After centrifugation (HC-2062) (5000 r/min × 10 min), serum samples were preserved at -80°C and were eventually used for investigation of IgG and IgA by ELISA. Body weight was recorded daily for 28 days, Nasal washes and mucosal sections were taken from the nasal cavity of mice on day 28. Then the mice were sacrificed by cervical dislocation, and the nasal septum, spleen and thymus samples was surgically removed on day 28.
Liu J., Yan X.D., Li X.Q., Du Y.H., Zhu L.L., Ye T.T., Cao Z.Y., Dong Z.W., Li S.T., Xu X., Bai W., Li D., Zhang J.W., Wang S.J., Li S.H., Sun J, & Yin X.Z. (2023). Chrysanthemum sporopollenin: A novel vaccine delivery system for nasal mucosal immunity. Frontiers in Immunology, 14, 1132129.
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Publication 2023
BLOOD Body Weight Centrifugation Enzyme-Linked Immunosorbent Assay Females Joint Dislocations Mice, House Mice, Inbred BALB C Mucous Membrane Nasal Cavity Neck Nose Operative Surgical Procedures Pharmaceutical Adjuvants Septums, Nasal Serum Spleen Thymus Plant Vaccination Vaccines
5
Epidemiology of Epistaxis: A Comprehensive Analysis
We collected the 403 cases of epistaxis diagnosed and treated by Tianjin Huanhu Hospital from January 2020 to January 2021, including 323 patients with primary nasal hemorrhage with complete clinical data and follow-up 6 months, and the control group was 182 healthy subjects from the same center during the same period.
All patients treated by Department of Otolaryngology of Tianjin Huanhu Hospital were screened out, with complete laboratory examination data, complete general clinical data and complete follow-up.
Septal hemorrhage can be treated with nasal packing in the emergency department, but non-septal hemorrhage, which needs endoscopic operation due to its deep location, according to different treatment methods, nasal hemorrhage was divided into nasal septum (196 cases) and non-nasal septum (127 cases). Nasal septum hemorrhage included the Little’s area, the posterior septum and the olfactory fissure area, and non-nasal septum hemorrhage included the lateral wall of the nasal cavity, the nasal roof and nasal floor. The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013. The study was approved by ethics board of Tianjin Huanhu Hospital (No. 2023-001) and individual consent for this retrospective analysis was waived.
The risk factors included history of hypertension, diabetes, cardiovascular and cerebrovascular diseases, anticoagulant use, smoking and drinking, blood pressure, height and weight [body mass index (BMI)], and routine blood, coagulation, and biochemistry tests, and different seasons
Hypertension is characterized by an increase in systemic arterial blood pressure (systolic and/or diastolic) (systolic ≥140 mmHg, diastolic ≥90 mmHg), The normal range of serum cholesterol is 0–5.18 mmol/L, the normal range of triglycerides is 0.7–1.7 mmol/L, the normal range of high-density lipoprotein (HDL) is 1.16–1.42 mmol/L, the normal range of low-density lipoprotein (LDL) is 0–4.47 mmol/L, and the normal range of apolipoprotein A1 is 1.2–1.8 mmol/L. Apolipoprotein B normal range 0.6 to 1.14 mmol/L. Normal BMI range: 18.5 to 23.9 kg/m2.
As for the seasons, March, April, and May are spring, June, July, and August are summer, September, October, and November are autumn, and December, January, and February are winter.
Li H.Y., Luo T., Li L., Liu Y., Zhai X, & Wang X.D. (2023). Etiology and clinical characteristics of primary epistaxis. Annals of Translational Medicine, 11(2), 96.
Publication 2023
Anticoagulants APOL1 protein, human Apolipoprotein A-I BLOOD Blood Pressure Cardiovascular System Cerebrovascular Disorders Cholesterol Coagulation, Blood Diabetes Mellitus Diastole Epistaxis Healthy Volunteers Hemorrhage High Blood Pressures High Density Lipoproteins Index, Body Mass Low-Density Lipoproteins Nose Patients Sense of Smell Septums, Nasal Serum Surgical Endoscopy Systole Transverse Sinuses Triglycerides

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Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
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More about "Septums, Nasal"

The nasal septum and surrounding nasal structures are critical components of the respiratory system, playing pivotal roles in airflow, olfaction, and overall nasal function.
This encompasses the anatomy, physiology, and pathology of the nasal septum, nasal cavity, and surrounding nasal structures.
Researchers can leverage advanced AI tools from PubCompare.ai to streamline nasal and septum-related studies, identifying the most effective protocols and methods from literature, preprints, and patents with enhanced reproducibility and accuracy.
This can optimize sepetal and nasal research for better science tomorrow.
Some key subtopics and related terms include: - Nasal airflow and respiration - Olfaction and smell - Nasal anatomy (e.g. nasal cavity, turbinates, nasal vestibule) - Nasal physiology (e.g. mucociliary clearance, nasal resistance) - Nasal pathology (e.g. septal deviation, rhinitis, sinusitis) - Nasal pharmacology (e.g. decongestants, nasal sprays) - Cell culture media like FBS, Penicillin/streptomycin, DMEM, DMEM/F12 - Antimicrobials like Penicillin, Streptomycin, Gentamicin, Kanamycin Leveraging AI-powered tools from PubCompare.ai can help researchers identify the most effective protocols, methods, and products for their nasal and septum-related studies, leading to more reproducible and accurate results.
Start your journey to better science today!