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> Anatomy > Body Space or Junction > Gomphosis

Gomphosis

Gomphosis, a type of fibrous joint, refers to the attachment of teeth to the alveolar bone of the jaw.
This specialized articulation allows for the secure anchoring of teeth while still permitting some degree of movement.
Gomphosis plays a crucial role in the function and stability of the dentition, facilitating chewing and other oral activities.
Researchers investigating this anatomical feature may utilize PubCompare.ai's AI-driven protocol comparison tool to identify the best protocols from literature, pre-prits, and patents, optimizing their Gomphosis-related studies for accuracy and reproducibility.

Most cited protocols related to «Gomphosis»

1
Scalable Whole-Genome Imputation with Hadoop
The Michigan Imputation Server implements the whole-genotype imputation workflow using the MapReduce programming model for efficient parallelization of computationally intensive tasks. We use the open source framework Hadoop to implement all workflow steps. Maintenance of the server, including node configuration (for example, amount of parallel tasks, memory for each chunk, and monitoring of all nodes), is achieved using the Cloudera Manager. During cluster initialization, reference panels, genetic maps, and software packages are distributed across all cluster nodes using the Hadoop file system HDFS. The imputation workflow itself consists of two steps: first, we divide the data into non-overlapping chunks (here, chromosome segments of 20 Mb). Second, we run an analysis (here, quality control or phasing and imputation) in parallel across chunks. To avoid edge effects, 5 Mb for phasing and 500 kb for imputation are added to each chunk. Finally, all results are combined to generate an aggregate final output.
Genotype imputation can be implemented with MapReduce, as the computationally expensive whole-genome calculations can be split into independent chromosome segments. Our imputation server accepts phased and unphased GWAS genotypes in VCF file format. File format checks and initial statistics (numbers of individuals and SNVs, detected chromosomes, unphased/phased data set, and number of chunks) are generated during the preprocessing step. Then, the submitted genotypes are compared to the reference panel to ensure that alleles, allele frequencies, strand orientation, and variant coding are correct. In this first MapReduce analysis, the map function calculates the VCF statistics for each file chunk, and the reducer summarizes the results and forwards only chunks that pass quality control to the subsequent imputation step (Supplementary Fig. 2). The MapReduce imputation step constitutes a map-only job. This means that no reducer is applied and each mapper imputes genotypes using minimac3 on the previously generated chunk. If the user has uploaded unphased genotypes, the data are prephased with one of the available phasing engines: Eagle 2, HAPI-UR34 (link), or SHAPEIT17 (link). A post-processing step generates a zipped and indexed VCF file (using bgzip and tabix35 (link)) for each imputed chromosome. To minimize the input/output load, the reference panel is distributed across available nodes in the cluster using the distributed cache feature of Hadoop. To ensure data security, imputation results are encrypted on the fly using a one-time password. All result files and reports can be viewed or downloaded via the web interface.
The imputation server workflow has been integrated into Cloudgene24 (link) to provide a graphical user interface. Cloudgene is a high-level workflow system for Apache Hadoop designed as a web application using Bootstrap, CanJs, and JQuery. On the server side, all necessary resources are implemented in Java using the RESTful web framework Restlet. The Cloudgene API provides methods for the execution and monitoring of MapReduce jobs and can be seen as an additional layer between Hadoop and the client. The imputation server is integrated into Cloudgene using the provided workflow definition language and its plugin interface. On the basis of the workflow information, Cloudgene automatically renders a web form for all required parameters to submit individual jobs to the Cloudgene server. The server communicates and interacts with the Hadoop cluster and receives feedback from currently executing jobs. Client and server communicate by asynchronous HTTP requests (AJAX) with JSON as an interchange format. All transmissions between server and client are encrypted using SSL (Secure Socket Layer).
Das S., Forer L., Schönherr S., Sidore C., Locke A.E., Kwong A., Vrieze S.I., Chew E.Y., Levy S., McGue M., Schlessinger D., Stambolian D., Loh P.R., Iacono W.G., Swaroop A., Scott L.J., Cucca F., Kronenberg F., Boehnke M., Abecasis G.R, & Fuchsberger C. (2016). Next-generation genotype imputation service and methods. Nature genetics, 48(10), 1284-1287.
Publication 2016
Alleles Chromosome Mapping Chromosomes Eagle Genome Genome-Wide Association Study Genotype Gomphosis Memory REST protein, human Transmission, Communicable Disease Vision
2
Musculoskeletal Modeling for Gait Analysis

Protocol full text hidden due to copyright restrictions

Open the protocol to access the free full text link

Publication 2011
Acceleration Adult Biceps Femoris Cadaver Cerebral Palsy Child Epistropheus Femur Foot Generic Drugs Gomphosis Gravitation Gravity Head Hip Joint Joints Joints, Ankle Knee Joint Muscle, Gastrocnemius Muscle Tissue Pelvis Plant Roots Quadriceps Femoris Rectus Femoris Semimembranosus Tibia Torso Vastus Intermedius Vastus Lateralis Vastus Medialis Vertebrae, Lumbar
3
Prospective Pregnancy Study Utilizing Online Recruitment and Data Collection
Enrollment and primary data collection are accomplished via the study website (http://presto.bu.edu) and email (bupresto@bu.edu). Potential female participants read an online consent form, complete a screening questionnaire, and provide a valid e-mail address that is subsequently confirmed. The confirmatory e-mail includes a link that directs women to a comprehensive online baseline questionnaire (median completion time: 32 minutes). Women are then encouraged to invite their male partner to complete an optional one-time baseline questionnaire (median completion time: 14 minutes). Ten days after enrollment, female participants are invited to complete the Dietary Health Questionnaire (DHQ) II,13 a web-based food frequency questionnaire developed and validated by the National Cancer Institute (median completion time: 40 minutes).
After completing the baseline questionnaire, women are randomized with 50% probability to receive a complimentary premium subscription to FertilityFriend.com (FF), a menstrual cycle charting and fertility information software program accessible via computer or smartphone. Existing FF users are not eligible for randomization. At every stage of the study (baseline, diet, and follow-up questionnaires), we can quantify the number of eligible participants who did not start their questionnaires or only filled out part of it. We can also compare demographic characteristics of ”partial responders” with ”responders” because demographic data were collected at the start of the baseline questionnaire. All data are protected using secure socket layering (SSL) encryption technology and are implemented by means of unique login names, passwords, and unique IP addresses of users’ computers. On a weekly basis, updated FF data are available to PRESTO investigators via download from a secure password-protected server.
Wise L.A., Rothman K.J., Mikkelsen E.M., Stanford J.B., Wesselink A.K., McKinnon C., Gruschow S.M., Horgan C.E., Wiley A.S., Hahn K.A., Sørensen H.T, & Hatch E.E. (2015). Design and conduct of an internet-based preconception cohort study in North America: Pregnancy Study Online (PRESTO). Paediatric and perinatal epidemiology, 29(4), 360-371.
Publication 2015
Diet Females Fertility Food Gomphosis Males Menstrual Cycle Woman
4
Zebrafish Larval Locomotor Assay for AEDs
Zebrafish larvae were incubated with AEDs at 28.5°C in complete darkness. After 90 min, each larva was individually checked under the microscope for the following signs of acute locomotor impairment: hypoactivity, decreased or no touch/escape response upon a light touch of the tail with a fine needle [13] (link), [14] (link), loss of posture, body deformation, exophthalmos (bulging of the eyes out of their sockets), slow or absent heartbeat, and death. After an overnight incubation (18 hours, 28.5°C, complete darkness), assessment of larvae for the same above-mentioned signs of toxicity was repeated. A larva was considered normal if it could cover a distance twice its body length. A shorter distance travelled or movement in the same place was scored as a decreased or impaired touch response. No visible movement upon a touch stimulus was counted as no response. The MTC was thus defined as the maximum concentration that did not cause death and where not more than two out of 12 larvae exhibited any sign of locomotor impairment including no touch response after an 18-hour incubation period. A decrease in spontaneous movement with retained ability to swim away in response to touch was considered an acceptable AED concentration for further testing.
Afrikanova T., Serruys A.S., Buenafe O.E., Clinckers R., Smolders I., de Witte P.A., Crawford A.D, & Esguerra C.V. (2013). Validation of the Zebrafish Pentylenetetrazol Seizure Model: Locomotor versus Electrographic Responses to Antiepileptic Drugs. PLoS ONE, 8(1), e54166.
Publication 2013
Automated External Defibrillators Darkness Exophthalmos Gomphosis Human Body Larva Light Microscopy Movement Needles Pulse Rate Tail Touch Zebrafish
5
Data Management and Visualization with JAnnot
Data management is done by a library, called JAnnot, which is developed in conjunction with GenomeView. JAnnot can also be used as an independent sequence analysis framework. The file types that JAnnot supports are listed in Table 2. The most common formats for genomics data are included. Most file-types are supported as read-only, except for the major annotation formats EMBL and GFF. While JAnnot supports multiple short-read alignment file formats, we strongly recommend users to convert their mappings to the BAM format described by Li et al. (41 (link)) using the SAMtools package. In a very short time, this format has gained broad support and seems to have become the de-facto standard for short-read alignments. GenomeView will automatically create index files and request the user to preprocess particular file format to more efficient alternatives.

Supported file formats in JAnnot, an up to date list is available at http://genomeview.org/content/data-formats

DescriptionFile types
Sequence and annotationEMBL, Genbank
Sequencefasta
AnnotationGFF, BED, Blast, GeneMark, PTT, TransTermHP TBL (Tair)
Multiple alignmentClustalW, MAF, multi-fasta
Short-read alignmentBAM, MAQ/MapView
Continuous values/coveragewiggle, TDF
Data can either be loaded from a local file, or straight from a URL that points to a file on a web server. For remote files, we have implemented Secure Sockets Layer (SSL) encryption and authentication (http-basic) protocols that are supported by most modern web servers, ensuring that data are transferred encrypted from the server to GenomeView and only to people who are authenticated with credentials provided by the owner of the data.
When saving data loaded from a URL, GenomeView uses an http-post to send the data with changes back. This can be used in conjunction with a web service that handles this post to set up a gene curation platform. Because GenomeView can readily load data from a web server, it is straightforward to integrate GenomeView in existing websites as a visualization front-end. The full specification on how to implement the integration and further instructions to interact with existing data is described in detail in the manual on the website (http://genomeview.org/content/integration).
Abeel T., Van Parys T., Saeys Y., Galagan J, & Van de Peer Y. (2011). GenomeView: a next-generation genome browser. Nucleic Acids Research, 40(2), e12.
Publication 2011
DNA Library Genes Gomphosis Sequence Analysis

Most recents protocols related to «Gomphosis»

1
Arthroplasty Dislocation Risk Factors
We calculated the cumulative incidence of dislocation using the Aalen–Johnson Estimator (competing risk analysis) with death and implant removal as competing risks. Results were reported as the point estimate with the 95% confidence interval (CI). We defined dislocation as a displacement of the femoral head from the joint socket. We included only the first dislocation when calculating the cumulative incidence of dislocation, after which we censored the patients. The cumulative incidence of dislocation was calculated for the entire cohort and stratified by type of articulating surface (regular THA, HA, CL, and DM) and by MBR. We restricted the analysis to the first surgery in the observation period for patients with bilateral surgery to avoid dependency issues (10 (link)). The difference between groups was assessed with Gray’s test. We analyzed the influence of age, sex, ASA score (1–2 vs. 3–4), Karnofsky Performance Status score (≥ 70 vs. < 70), MBR, and type of articulation on the risk of dislocation using cause-specific Cox proportional hazards regression. We checked the proportional hazard assumption by evaluating the Schoenfeld residuals for each variable and found that the proportional hazard assumption was not violated. We calculated the overall survival and survival stratified by articulation type and MBR using the Kaplan–Meier estimate for cumulative survival. The difference between the survival curves stratified by articulation type and MBR was evaluated with the log-rank test. R version 4.2 (R Foundation for Statistical Computing, Vienna, Austria) was used for the statistical analysis.
ILJAZI A., SØRENSEN M.S., LADEGAARD T.H., OVERGAARD S, & PETERSEN M.M. (2023). Dislocation rate after hip arthroplasty due to metastatic bone disease: a retrospective cohort study evaluating the postoperative dislocation risk across different articulating solutions. Acta Orthopaedica, 94, 107-114.
Publication 2023
Femur Heads Gomphosis Joint Dislocations Joints Operative Surgical Procedures Patients
2
Alveolar Bone Height Classification for Implant Placement
ABH is important in achieving primary stability vertically and is measured from the crestal bone to the maxillary sinus floor through the radiograph. The result will determine the indication for socket lifting.(Fig. 1) Classification of ABH is as follows:
• Grade A: ABH>8.0 mm; sufficient to contain the fixture in the vertical dimension and does not require socket lifting.
• Grade B: 6.0 mm≤ABH≤8.0 mm; may or may not require socket lifting, socket lifting is required for a longer implant.
• Grade C: ABH<6.0 mm; insufficient ABH, socket lifting is mandatory.
Mustakim K.R., Eo M.Y., Lee J.Y., Myoung H., Seo M.H, & Kim S.M. (2023). Guidance and rationale for the immediate implant placement in the maxillary molar. Journal of the Korean Association of Oral and Maxillofacial Surgeons, 49(1), 30-42.
Publication 2023
Bones Gomphosis Maxillary Sinus X-Rays, Diagnostic
3
Immediate Implant Placement in Extraction Sockets
After obtaining informed consent, surgery was performed under local anesthesia using 2% lidocaine with 1:100,000 epinephrine. Atraumatic tooth extraction was performed without flap elevation, and a diamond bur was used to separate the roots to preserve the interradicular septum and the buccal bone. The socket was debrided thoroughly using a surgical curette and sterile saline irrigation.
For Grade C cases, the socket was tapped using a blunt sinus osteotome with a proper force to elevate the sinus floor.(Fig. 5) We chose the length and the diameter of SLA implants based on the bone height and width measurements. The fixture was placed in the mid-point of the interradicular septum parallel to the central fossa line of the adjacent teeth and lower than the lowest extraction margin.(Fig. 2, 4) In the Grade A Type III case, the wide diameter Anyone (Megagen, Seoul, Korea) bone level implant (6.5 mm×8.5 mm) was used to occupy most of the extraction socket.(Fig. 7) The primary stability of the implant was confirmed. In the Grade A Type II case, bone grafting was performed using particulate allogeneic bone Oragraft (LifeNet Health, Virginia Beach, VA, USA) to fill the gap between the fixture and the surrounding bone, followed by application of a resorbable collagen bilayer membrane, Bio-Gide (Geistlich, Princeton, NJ, USA).(Fig. 6) Sutures were placed with proper tension using 4-0 polyglactin 910 Vicryl (Johnson & Johnson, New Brunswick, NJ, USA) in cases without bone grafting to maintain the convexity of the buccal bone. Tension-free suturing using 4-0 polyglactin 910 Vicryl was performed in cases of bone grafting to fix the membrane.
Mustakim K.R., Eo M.Y., Lee J.Y., Myoung H., Seo M.H, & Kim S.M. (2023). Guidance and rationale for the immediate implant placement in the maxillary molar. Journal of the Korean Association of Oral and Maxillofacial Surgeons, 49(1), 30-42.
Publication 2023
Bio-Gide Bones Cheek Bone Collagen Diamond Epinephrine Gomphosis Lidocaine Local Anesthesia Operative Surgical Procedures OraGraft Osteotomy Plant Roots Polyglactin 910 Saline Solution Sinuses, Nasal Sterility, Reproductive Surgical Flaps Tissue, Membrane Tooth Tooth Extraction Venous Catheter, Central Vicryl
4
Implant Socket Morphology and Stability
To achieve lateral primary stability, the morphology of the socket plays an important role. Following the extraction procedure, the interradicular septum of the socket was confirmed clinically to determine the need for bone grafting or a wide-diameter implant (Fig. 1):
• Type I: Interradicular septum can support and integrate well with the implant. Bone grafting is not mandatory.
• Type II: Interradicular septum support for the implant is available but weak; bone grafting is required for primary stability of the implant fixture.
• Type III: The interradicular septum bone is absent to provide primary stability within the socket, and fixture stabilization only depends on the socket wall. In this type, a wide implant diameter can replace most of the extraction socket.
After applying the inclusion and exclusion criteria, the final group contained 26 patients. We presented eight representative cases each of ABH and interradicular septum type; two cases with Grade A Type I including one (Fig. 2) and two immediate implants (Fig. 3); one case with Grade B Type I (Fig. 4); three cases with Grade C Type I (two of which required reinstallation with and without sinus lifting) (Fig. 5); one case with Grade A Type II (Fig. 6); and one case with Grade A Type III.(Fig. 7)
Mustakim K.R., Eo M.Y., Lee J.Y., Myoung H., Seo M.H, & Kim S.M. (2023). Guidance and rationale for the immediate implant placement in the maxillary molar. Journal of the Korean Association of Oral and Maxillofacial Surgeons, 49(1), 30-42.
Publication 2023
Bones Debility Gomphosis Patients Sinuses, Nasal
5
Alveolar Socket Preservation Protocol
G*Power 3.1.9.2 software was used a priori to define sample size (Fig. 1 SI). This pilot study was designed for a two-tailed analysis with Student’s t-test or Wilcoxon signed rank test (depending on the normality of the results), with a confidence interval (statistical power) of 95% (1 − β = 0.95), with a probability of occurrence of a type 1 error of 5% (α = 0.05) and assuming an effect size dz of 2. The analysis determined that a total of 6 participants for each group were needed to meet aforementioned parameters for the primary endpoint of this study: the volume of bone formed after 6 months equals to the initial post-extraction alveolar volume. All of the participants underwent tooth extraction and socket preservation, with test and control group materials (parallel group design), for 6 months before implant placement.
The overall clinical study involved seven visits to the study facilities by each patient, as listed in Table 1. Postoperative clinical evaluations were performed after 3, 10, and 24 days to determine the presence of any complications such as infection, inflammation, wound dehiscence, or loss of graft material. After 6 months, clinical examinations were performed following implant placement. Afterwards, patients were still closely followed by the dentist over an extended period, however, with no relevance to this paper.

Overall study procedures listed by order of accomplishment

Medical visitMain procedures
1st recruitment interviewThe candidate is invited to participate in the study; the anamnesis, inclusion, and exclusion criteria are reviewed; and if the candidate is eligible to participate, the information leaflet and declaration of consent are signed
2nd pre-surgical visitComputed tomography (CT). This visit could be done on the same day as the candidate’s recruitment interview or the same day as the surgical visit
3rd surgical interventionSurgery for tooth extraction, fill the alveolar socket with medical device and closure of the surgical wound
4th first check-up visit3 days post-surgery: check-up for visual examination of the extraction site and tissue condition
5th second check-up visit1 week after first check-up visit: check-up for visual examination of the extraction site and tissue condition, and for suture removal
6th third check-up visit2 weeks after second check-up visit: check-up for visual examination of the extraction site and tissue condition
7th pre-surgical visit6 months post-surgery: CT examination. This visit could be done few days before or on the same day as the surgical re-entry
8th surgical re-entry6 months post-surgery: collect bone sample and evaluate tissue condition, following implant placement
Machado A., Pereira I., Costa F., Brandão A., Pereira J.E., Maurício A.C., Santos J.D., Amaro I., Falacho R., Coelho R., Cruz N, & Gama M. (2023). Randomized clinical study of injectable dextrin-based hydrogel as a carrier of a synthetic bone substitute. Clinical Oral Investigations, 27(3), 979-994.
Publication 2023
Biologic Preservation Bones Dentist Gomphosis Grafts Immunologic Memory Infection Inflammation Medical Devices Operative Surgical Procedures Patients Physical Examination Student Sutures Tissues Tomography Tooth Extraction Wounds

Top products related to «Gomphosis»

1
Binocular light microscope by Olympus
Sourced in Japan
The Binocular Light Microscope is a laboratory equipment designed to provide high-magnification visual observation of small samples. It utilizes a system of lenses to magnify and illuminate the subject, allowing for detailed examination of microscopic structures.
2
Bio gide by Geistlich Pharma
Sourced in Switzerland, United States
Bio-Gide is a collagen membrane product designed for dental and oral surgery applications. It is a biodegradable and native collagen matrix made from highly purified porcine collagen. Bio-Gide provides a scaffold for tissue regeneration.
3
Bio oss collagen by Geistlich Pharma
Sourced in Switzerland
Bio-Oss® Collagen is a bone grafting material composed of natural cortico-cancellous bone mineral and type I collagen. It is intended for use in dental and maxillofacial procedures to support bone regeneration.
4
Flipcutter by Arthrex
Sourced in United States
The FlipCutter is a surgical instrument used in arthroscopic procedures. It features a rotational and flipping mechanism that allows for accurate and controlled tissue cutting. The device is designed to facilitate precise tissue removal and shaping during joint procedures.
5
Matlab by MathWorks
Sourced in United States, United Kingdom, Germany, Canada, Japan, Sweden, Austria, Morocco, Switzerland, Australia, Belgium, Italy, Netherlands, China, France, Denmark, Norway, Hungary, Malaysia, Israel, Finland, Spain
MATLAB is a high-performance programming language and numerical computing environment used for scientific and engineering calculations, data analysis, and visualization. It provides a comprehensive set of tools for solving complex mathematical and computational problems.
6
Bio oss by Geistlich Pharma
Sourced in Switzerland, Germany, Italy, United States
Bio-Oss is a bone substitute material derived from bovine bone. It is a porous and natural mineral scaffold that provides a framework for new bone formation.
7
Rm2255 by Leica
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The RM2255 is a rotary microtome designed for sectioning a wide range of paraffin-embedded tissue samples. It features a vertical specimen feed with a stroke of 70 mm and a section thickness range of 0.5 to 100 μm. The RM2255 is equipped with a precision feed mechanism and a high-quality steel knife holder for consistent and accurate sectioning.
8
Skyscan 1076 by Bruker
Sourced in Belgium, United States, Germany
The SkyScan 1076 is a high-resolution in vivo micro-CT scanner designed for small animal imaging. It provides non-invasive, three-dimensional imaging of the internal structure of small samples with a high level of detail.
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Microxct 200 by Zeiss
Sourced in United Kingdom
The MicroXCT-200 is a high-resolution X-ray microscope system designed for non-destructive 3D imaging and analysis of a wide range of materials and samples. It provides high-quality, high-resolution 3D data without the need for complex sample preparation.
10
Teflon coated silver wire by A-M Systems
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Teflon-coated silver wire is a type of lab equipment designed for use in various scientific and industrial applications. The wire is made of silver and coated with a layer of Teflon, a durable and non-stick material. The core function of this product is to provide a conductive and corrosion-resistant material that can be used in a variety of laboratory settings.

More about "Gomphosis"

Gomphosis, a specialized type of fibrous joint, refers to the secure attachment of teeth to the alveolar bone in the jaw.
This anatomical feature plays a crucial role in the function and stability of the dentition, enabling chewing and other oral activities.
Researchers investigating Gomphosis may utilize PubCompare.ai's AI-driven protocol comparison tool to identify the best protocols from literature, pre-prints, and patents, optimizing their studies for accuracy and reproducibility.
Gomphosis, also known as a desmostosis or ginglymus joint, allows for a degree of tooth movement while firmly anchoring the teeth in place.
This specialized articulation is essential for the proper functioning of the dentition.
Researchers studying Gomphosis may employ various tools and techniques, such as binocular light microscopy, Bio-Gide and Bio-Oss Collagen membranes, FlipCutter devices, MATLAB software, Bio-Oss bone grafting material, RM2255 microCT scanners, SkyScan 1076 microtomographs, and MicroXCT-200 imaging systems.
The use of Teflon-coated silver wire may also be relevant in some Gomphosis-related investigations.
By utilizing PubCompare.ai's AI-powered protocol comparison tool, researchers can identify the optimal solutions and best practices for their Gomphosis studies, enhancing the accuracy and reproducibility of their findings.
This AI-assisted approach can prove invaluable in advancing our understanding of this crucial anatomical feature and its role in oral health and function.