The largest database of trusted experimental protocols
> Anatomy > Body Space or Junction > Metacarpophalangeal Joint

Metacarpophalangeal Joint

The Metacarpophalangeal Joint is the joint between the metacarpal bone and the proximal phalanx of each finger.
It allows for flexion, extension, abduction, and adduction of the fingers, enabling dexterous hand movements essential for many daily activities.
Proper understanding and evaluation of this joint is crucial for assessing hand function and diagnosing related musculoskeletal conditions.
PubCompare.ai's AI-driven protocol comparison tool can help researchers optimize their Metacarpophalangeal Joint studies by identifying the most effective products and methods from literature, preprints, and patents, enhancing reproducibility and accruacy.

Most cited protocols related to «Metacarpophalangeal Joint»

The initial step, performed during a 2-day exercise, aimed at evaluating intraobserver and interobserver reliability for scoring static images and scoring images acquired in real-time while scanning patients.
Reading static images (day 1). Static images, representing a broad range of different degrees of synovitis in the metacarpophalangeal (MCP), wrist, proximal interphalangeal (PIP) and metatarsophalangeal joints (MTP) of patients with RA attending the Rheumatology Department of Ambroise Paré Hospital in Boulogne-Billancourt (France) were anonymised by the convenor (MADA). Images were obtained using the preliminary OMERACT definition for synovitis which includes both GS (SH and effusion) and PD findings. Images were acquired according to the EULAR recommendations16 (link) with a longitudinal scan obtained using either a dorsal or volar (plantar) view. Seventeen musculoskeletal sonographers (from Denmark, France, Germany, Hungary, Ireland, Italy, Netherlands, Spain, UK and USA) simultaneously but independently scored the images, which were presented randomly presented with 60 s for evaluating each image. No patient information was made available. Participants were asked to score GS and PD using both a binary (presence/absence) and SQ grading from 0 to 3 (normal, minimal, moderate, severe), according to their own daily practice, on a preprinted data collection sheet.
Acquiring and reading images (day 2). A practical exercise was then conducted the following day scanning and scoring synovitis. Eight patients with RA17 (link) were recruited from the same Rheumatology Department each having only mild to moderate hand deformities in order to eliminate possible acquisition difficulties due to severe structural deformities including ankylosis. The study was conducted in accordance with the Declaration of Helsinki and each participant gave written informed consent. The examinations were performed on the same day, in the same room, using eight identical machines (Technos MPX - Esaote Biomedica, Genoa, Italy) equipped with a 10–14 MHz broadband linear array transducer. The machines were calibrated with identical Doppler settings (frequency of 10.1 MHz, pulse repetition frequency of 750 Hz and Doppler gain of 50–53 dB). In this way, the impact of machines on the results was minimised. Fourteen rheumatologists who participated on the first day, in step 1, participated on the second day; all were blinded to the clinical details of the patients (ie, presence or not of active disease). Each patient was assigned to one machine and the sonographers then rotated from one machine to the next in a predefined sequence with 10 min allocated for scanning and recording the findings on a standard score sheet. In each patient, the second to fifth MCP and second to fifth PIP joints were scanned bilaterally using a GS and PD longitudinal scan in the midline of the joint on both the dorsal and volar aspects. Sixteen MCP joints were scanned twice in order to assess the intraobserver reliability.
Full text: Click here
Publication 2017
Ankylosis Congenital Abnormality Hand Deformities Joints Mandibuloacral dysplasia with type A lipodystrophy Metacarpophalangeal Joint Metatarsophalangeal Joint Patients Physical Examination Pulse Rate Rheumatologist Synovitis Transducers Wrist
Laparotomy and sham surgeries were performed using aseptic procedures under halothane anesthesia using a previously described method developed as a model of human abdominal exploratory surgery (Martin et al., 2005 (link)). The abdominal region was shaved and thoroughly cleaned with 70% ethanol and surgical scrub. Approximately 0.5 cm below the lower right rib, a 3 cm vertical incision was made, penetrating the peritoneal cavity. Wearing sterile latex gloves, the surgeon inserted an index finger up to the second knuckle into the opening and vigorously manipulated the viscera and musculature. Approximately 10 cm of the intestine were then exteriorized and vigorously rubbed between the surgeon's thumb and index finger for 30 s. The intestines were then placed back into the peritoneal cavity. Sterile chromic gut sutures (3–0, chromic gut, 27 in., PS-2; Ethicon) were used to suture the peritoneal lining and abdominal muscle in two layers. The skin was closed with surgical staples. To prevent infection, the wound was dressed with Polysporin (Pfizer, Morris Plains, NJ). Sham-operated rats were anesthetized, and abdominal area was shaved and cleaned as described above. They remained on halothane for the same amount of time as their surgical counterpart (~25 min).
Publication 2012
Abdomen Abdominal Muscles Anesthesia Asepsis Ethanol Fingers Halothane Homo sapiens Infection Intestines Laparotomy Latex Metacarpophalangeal Joint Operative Surgical Procedures Peritoneal Cavity Peritoneum Polysporin Rattus norvegicus Skin Staple, Surgical Sterility, Reproductive Surgeons Surgical Scrubbing Sutures Thumb Viscera Wounds
Subjects’ Monofilament and Two-Point Discrimination scores for the index and thumb fingertips were compared with and without noise. Specifically, sensory scores without noise were recorded at the beginning (pre) and end (post) of the testing session. Sensory scores for the pre and post test were compared to ensure no learning effect and no residual effect of noise after the exposure during the one day testing session. In between the pre and post sensory tests without noise, sensory scores with noise were recorded while subthreshold vibrotactile noise was applied to four different locations at three noise intensities. The subthreshold vibrotactile noise was turned on immediately before each sensory test and was turned off immediately after each sensory test (lasting approximately 1 minute each). The testing session lasted for approximately two hours for each subject.
Subthreshold vibrotactile noise was white noise bandwidth filtered at 0 to 500 Hz, applied with a C-3 Tactor (Engineering Acoustics, Inc. Casselberry, Florida). Due to the characteristics of the C-3 Tactor, the vibration amplitude could have been larger for 100-300 Hz which includes the sensitive range of the Pacinian corpuscles. The noise was applied to one of four locations in the paretic upper limb (Figure 1): 1) dorsal hand approximately 2 cm proximal to the index finger knuckle; 2) dorsal hand approximately 2 cm proximal to the thumb knuckle; 3) dorsal wrist, medial to the radial styloid process; and 4) volar wrist, medial to the radial styloid process. These locations were arbitrarily chosen with the intention of developing a future wearable rehabilitation device for stroke survivors. Since the long-term goal of the research is to improve dexterity and grip control, noise locations that would interfere with gripping, such as the fingertip or palm, were avoided. Presentation of noise locations was block randomized.
Noise intensities were set to 40%, 60%, or 80% of the sensory thresholds specific for each location. The order of testing different noise intensities was randomized within each location block. To determine the sensory threshold, the noise intensity was increased and decreased until the subject was barely able to distinguish between an “off” and an “on” presentation of the vibrotactile noise (i.e., the method of ascending and descending limits [22 (link)]). Subjects’ mean sensory threshold occurred when the Tactor was driven by current of 0.17 A peak-to-peak (Table 1). There is a linear relationship between the current and amplitude of the vibration. According to the data sheet from the manufacturer, 0.17 A peak-to-peak corresponds to a maximum amplitude of 260 μm. Subthreshold noise intensities were chosen not only so that subjects could not distinguish between trials with and without noise [21 (link)], but also because suprathreshold noise has been shown to degrade performance [23 (link)].
The Monofilament and Two-Point Discrimination Tests were administered using standard testing measures. For the Monofilament score, beginning with the baseline 2.83 Monofilament (indicating the threshold for “normal sensing”), the Monofilament was applied to the fingertip at least three times and the smallest Monofilament for which the subjects responded “yes” and could identify the correct finger that was touched marked the score [29 ]. The Two-Point Discrimination test was conducted so that subjects were asked to respond either “one” for a single point and “two” for two points separated by a small distance [29 ]. One and two point stimuli were alternated randomly. The smallest distance where the subjects responded correctly three consecutive times to identifying two separated points was used for their Two-Point Discrimination score. A score of 2.83 [30 ] and 5 mm [31 (link)] was considered normal for the Monofilament test and Two-Point Discrimination tests, respectively.
Full text: Click here
Publication 2013
Acoustics Arecaceae Cardiac Arrest Cerebrovascular Accident Discrimination, Psychology Fingers Metacarpophalangeal Joint Pacinian Corpuscles Rehabilitation Survivors Thumb Upper Extremity Vibration Wrist Joint
Patients underwent bilateral PDUS examinations of metacarpophalangeal joints (MCPs) 2–5 at screening and baseline, and of 44 (22 paired) joints (MCPs 1–5, proximal interphalangeal joints (PIPs) 1–5, wrist, elbow, shoulder (glenohumeral), knee, ankle (tibiotalar), hind foot (talonavicular and calcaneocuboidal) and metatarsophalangeal joints (MTPs) 1–5) at baseline (day 1), and at weeks 1, 2, 4, 6, 8, 12, 16, 20 and 24. The PDUS examinations were performed at each site by an independent expert in musculoskeletal ultrasound who was blinded to the clinical evaluations. Medium-level to high-level ultrasound machines were used (Esaote Technos MPX, MyLab 70, Toshiba Aplio, GE Logic (series 5, 7, 9 and E 9) or Siemens Acuson Antares), employing high-frequency (12–18 MHz) transducers. Doppler parameters were adjusted according to the device used (range of pulse repetition frequency 400–800 Hz; Doppler frequency 7–11.1 MHz).8 (link)
The presence of hypoechoic synovial hyperplasia (SH) and joint effusion (JE), both assessed using greyscale, and of synovial vascularisation, assessed using power Doppler (PD), were scored using semiquantitative scales. The presence of synovitis (SH and PD, without JE) was scored for each joint according to the semiquantitative OMERACT-EULAR-US composite PDUS scale, giving a score of 0–3 for each joint. GLOESS was calculated for MCPs 2–5 of both hands and for the 22 paired joints, using the sum of the composite PDUS scores for all joints examined, giving a potential score of 0–24 for MCPs 2–5, and of 0–132 for the 22 paired joints. A new reduced, 9 paired joint set score (including both large and small joints: shoulder, elbow, wrist, MCP1, MCP4, PIP2, knee, MTP3 and MTP5) was also determined using principal component analysis and was found to adequately represent the comprehensive 22 paired joint GLOESS.8 (link)
Publication 2016
CCL2 protein, human Foot Hydrarthrosis Hyperplasia Joints Joints, Ankle Joints, Elbow Joints, Hand Knee Joint Medical Devices Metacarpophalangeal Joint Metatarsophalangeal Joint Pathologic Neovascularization Patients Physical Examination Pulse Rate Shoulder Synovitis Transducers Ultrasonics Wrist
PIA was induced in 8–11 week old rats by an intradermal injection of 100 μl pristane (2,6,10,14-tetramethylpentadecane, 95%, Acros Organics, Morris Plains, NJ, USA) at the dorsal side of the tail base if not stated otherwise. Adjuvant, oil-induced and collagen-induced arthritides were induced by intradermal injections of 100 μl IFA (Difco Laboratories, Detroit, MI, USA) containing 0.4 mg of Mycobacterium butyricum (Difco), 300 μl pure IFA, and 0.3 mg pepsin-digested collagen type II (CII) purified from rat chondrosarcoma [24 ], dissolved in 150 μl 0.1 M acetic acid and emulsified in an equal volume of IFA, respectively. Synthetic pristane was obtained from Sigma-Aldrich (P2870; St. Louis, MO, USA). Treated and non-treated rats or rats subjected to different immunization protocols were housed together in cages. The evaluation of clinical arthritis is described in detail in S1 Text. In brief, 1 point was given for each inflamed knuckle or toe and up to 5 points was given for an affected ankle (in total 15 points per paw, 60 points per rat). Scores were not given for deformations if not accompanied by erythema. The day of disease remission is defined here as the first of at least three consecutive scoring days with declining arthritis scores. The 'first relapse' (Table 1) is the first of at least three consecutive scoring days with increasing scores following a period of disease remission. The frequency of chronic arthritis is defined as the proportion of rats with a mean score of ≥5 or at least two days with scores >6 following day 60 after immunization.
Full text: Click here
Publication 2016
Acetic Acid Ankle Arthritis Arthritis, Collagen-Induced Chondrosarcoma Collagen Type II Erythema Intradermal Injection Menstruation Disturbances Metacarpophalangeal Joint Mycobacterium Pepsin A Pharmaceutical Adjuvants pristane Rattus norvegicus Relapse Tail Vaccination

Most recents protocols related to «Metacarpophalangeal Joint»

In order to quantify upper limb tremor for comparison, we collected two continuous tremor signals, which were tremor acceleration and EMG signals, respectively. Before experiment, the tremor type (postural tremor/resting tremor) to record of each subject was decided independently by a physician after patient's enrollment. The main principle of choosing the main tremor type is tremor intensity and stability. Intentional tremor was not considered in our research since it is difficult to standardize motion. For subjects whose main tremor type is resting tremor, we had them seated comfortably with arms fully supported on armrests and recorded their tremor. For the others, postural tremor was inspected with seated subject stretching the whole upper limb forward and maintaining the posture for some time (Zhang et al., 2018 (link)). Additional requirements in recording postural tremor included: (1) fingers closed, (2) palms facing downward, and (3) seated upright.
All data was recorded through a commercial device system named the Biometrics Datalog (Biometrics Inc., the USA), along with a three-axis accelerometer sensor and four surface EMG (sEMG) sensors. The accelerometer sensor was fixed onto the third knuckle of the middle finger on the more affected side. Four sEMG sensors were attached respectively onto the muscle bellies of the flexor carpi radialis (FCR), the flexor carpi ulnaris (FCU), the extensor carpi radialis (ECR) and the extensor carpi ulnaris (ECU). The data of tremor acceleration and EMG signals were both digitized into 1,000 Hz and simultaneously recorded. From each subject, we obtained a 5-min sequential data package comprising tremor acceleration and EMG signals.
Full text: Click here
Publication 2023
Acceleration Action Tremor Arecaceae Arm, Upper Continuous Tremor Epistropheus Fingers Medical Devices Metacarpophalangeal Joint Muscle Tissue Physicians Resting Tremor Static Tremor Surface Electromyography Tremor Tremor, Limb Upper Extremity Wrist
This study was performed in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of Children’s Hospital of Nanjing Medical University (Approval number: 202205087-1). The informed consent was obtained from the parents/guardians of all participants. Patients with Benson type 1 camptodactyly treated in our institute between January 2019 and January 2021 were retrospectively analyzed. The inclusion criteria involved (1) 5th digit flexion deformity present at birth, (2) age > 1 year, and (3) moderate-to-severe deformity. The exclusion criteria involved (1) Benson types II and III camptodactyly, (2) camptodactyly in association with a syndrome, and (3) acquired camptodactyly.
A total of 12 digits (5 on the right and 7 on the left) in 8 patients (7 male and 1 female) were involved. The mean age was 4.9 years (range 1–11 years). Among them, 3 digits were previously treated conservatively. Camptodactyly was determined using the Bouvier maneuver, which involved extending the PIP joint while flexing the metacarpophalangeal joint to assess for contracture of the flexor digitorum superficialis tendon. The mean total passive motion (TPM) was 32.5°. And total active motion (TAM) of the PIP joint was 22°.
Full text: Click here
Publication 2023
Camptodactyly 1 Child Childbirth Congenital Abnormality Contracture Ethics Committees, Clinical Fingers Joints Legal Guardians Males Metacarpophalangeal Joint Parent Passive Range of Motion Patients Syndrome Tendons Woman
Participants will undergo imaging by MSUS at baseline and 4, 12, 24, 36, and 52 weeks performed by one of the JCR-certified sonographers. A systematic multiplanar grayscale (GS) and power Doppler (PD) examination of each patient’s joints will be performed using a multifrequency linear transducer (12–24 MHz). Depending on which Doppler modality is the most sensitive on the individual machines, PD will be used. The Doppler settings will be adjusted at each hospital according to published recommendations [21 (link)]. During the study, no change in MSUS settings and no software upgrading will occur.
Articular synovitis will be assessed by MSUS on dorsal views of 22 joints: bilateral wrist joints, 1st–5th metacarpophalangeal joints, interphalangeal joints, and 2nd–5th proximal interphalangeal joints. GS grade semiquantitatively scores the degree of synovial hypertrophy of each joint as within normal limits (grade 0), minimal (grade 1), moderate (grade 2), or severe (grade 3). In addition, PD grade semiquantitatively scores the degree of synovial PD signal of each joint as within the normal range (grade 0), minimal (grade 1), moderate (grade 2), and severe (grade 3) [22 (link), 23 (link)]. The sum of the GS or PD scores is considered to be the total GS or PD scores, respectively. We will also assess the Outcome Measures in Rheumatology (OMERACT)-EULAR combined PDUS score (i.e., the combined PD score) and Global OMERACT-EULAR Synovitis Score [22 (link), 23 (link)]. The combined PD score is combined with synovial hypertrophy shown by GS and PD [22 (link), 23 (link)].
Full text: Click here
Publication 2023
Joints Maple Syrup Urine Disease Metacarpophalangeal Joint Physical Examination Synovial Hypertrophy Synovitis Transducers Wrist Joint
Hyperspectral imaging technique for the non-invasive, bedside measurement of tissue oxygenation, hemoglobin and water content is based on the specific light reflection and absorption of different compounds such as oxy-/deoxyhemoglobin and water. The TIVITA® Tissue System (Diaspective Vision GmbH, Am Salzhaff, Germany), a CE-certified and validated class I medical device, was used for HSI measurements. The camera system was applied following the operating instructions and European medical device regulation. The physical principles of the measurement, technical specifications, and algorithms of the HSI camera system have been described in detail by Holmer et al. (11 ). A measurement procedure requires only a few seconds and allows the calculation of the following parameters from specified wavelength ranges (6 (link), 11 ):
Tissue oxygenation is indicated in percent (0–100%), NIR, THI, and TWI are indicated in predefined arbitrary units (0–100). The parameters are displayed to the operator as color-coded images in addition to the RGB-image (Figure 1). Areas with high values (50–100) are shown in shades from red to yellow, whereas areas with low values (0–50) are presented in green to blue shades. HSI measurements were performed on the right hand, using the analysis software circular regions of interest with a diameter of 70 units were defined in palm area (the circle crossing the metacarpophalangeal joint 3–4) while the diameter used for the fingertips 2–5 measured only 13 units. The mean of the four values was therefrom calculated. The treating physicians had no access to the HSI measurement results to avoid an influence on clinical therapy.
Full text: Click here
Publication 2023
Arecaceae Cell Respiration deoxyhemoglobin Europeans Hemoglobin Light Medical Devices Metacarpophalangeal Joint Neoplasm Metastasis Physical Examination Physicians Reflex Therapeutics Tissues Vision
Outcome measures will be gathered at baseline and weeks 3, 5 and 8 after the commencement of treatment (Table 1).
The primary outcome measure will be passive PIPJ extension. Passive PIPJ extension will be assessed in a standardised way as described by American Society of Hand Therapists (ASHT) [18 ]. Assessment of Passive Range of Motion (PROM) with a goniometer has been shown to be consistently reliable when standardised methods are implemented [18 ].
Secondary outcome measures for this study will include AROM and PROM of other joints, grip strength, oedema, pain level, function and treatment adherence will be captured.
AROM of all the joints of the injured digit including the Metacarpal Phalangeal Joint (MCPJ), PIPJ and DIPJ. This will be compared to the contralateral uninjured digit and will be undertaken using a single goniometer. In addition to AROM, Total Action Motion will be calculated and compared to the uninjured contralateral digit as per the ASHT guidelines [18 ].
PROM of all the joints of the injured digit will be compared to the contralateral uninjured digit and will be undertaken using a single goniometer. PROM can provide information about a joint’s capacity for motion [19 ] and ensure the home exercise program is tailored specifically to the patients’ impairments. In addition, Total Passive Motion will be calculated and compared to the uninjured contralateral digit [18 ].
Grip strength will be assessed using a standardised Jamar Dynamometer and adopting a standardised testing procedure as per the ASHT guidelines [19 ]. A single score of maximum effort will be recorded for the injured and uninjured side [20 (link)].
Oedema will be assessed using standardised testing procedure as described by ASHT guidelines. A standardised tape measure will be used to take a circumferential measurement of the PIPJ [21 ] and compared to the contralateral uninjured side.
Pain will be assessed using a Numerical Rating Scale. The patient will be asked to rate their pain between ‘0' and ‘10', with ‘0' describing ‘no pain’ and ‘10’ used to describe ‘worst pain imaginable’. Pain will also be assessed using the pain section of the Patient Rated Wrist and Hand Evaluation (PRWHE), which has been demonstrated to be a valid and reliable assessment of patient rated function and disability and complements the Numerical Rating Scale to assess pain in a holistic way [22 ].
Function will be assessed using the PRWHE, which has been shown to have good levels of evidence for validity, reliability [23 ] and responsiveness to trauma [24 (link)]. Return to work/everyday activities status will be determined by asking the patient if they have returned to their pre-injury roles, modified role or not at all. The adverse impact of hand injuries on return to work and everyday activities have been reported in the literature [25 (link)].
Adherence to treatment will be assessed via a questionnaire developed based on the work of SandfordBarlow [26 (link)]. The questionnaire asks the same key questions regarding adherence to treatment such as, if the splint has been removed, how often it may have been removed and why it may have removed but adapted slightly to reflect the different diagnostic group. This will be measured at the three-week assessment point, after this stage, patients will cease wearing the orthosis/buddy loop full time and commence a weaning process.
Full text: Click here
Publication 2023
BAD protein, human Bones of Fingers Braces Complement System Proteins Diagnosis Disabled Persons Edema Fingers Hand Injuries Injuries Joints Joints, Finger Metacarpophalangeal Joint Pain Measurement Passive Range of Motion Patients Splints Wounds and Injuries Wrist

Top products related to «Metacarpophalangeal Joint»

Sourced in United States, United Kingdom, Germany, China, France, Canada, Japan, Australia, Switzerland, Italy, Israel, Belgium, Austria, Spain, Brazil, Netherlands, Gabon, Denmark, Poland, Ireland, New Zealand, Sweden, Argentina, India, Macao, Uruguay, Portugal, Holy See (Vatican City State), Czechia, Singapore, Panama, Thailand, Moldova, Republic of, Finland, Morocco
Penicillin is a type of antibiotic used in laboratory settings. It is a broad-spectrum antimicrobial agent effective against a variety of bacteria. Penicillin functions by disrupting the bacterial cell wall, leading to cell death.
Sourced in United States, United Kingdom, Germany, China, France, Canada, Australia, Japan, Switzerland, Italy, Belgium, Israel, Austria, Spain, Netherlands, Poland, Brazil, Denmark, Argentina, Sweden, New Zealand, Ireland, India, Gabon, Macao, Portugal, Czechia, Singapore, Norway, Thailand, Uruguay, Moldova, Republic of, Finland, Panama
Streptomycin is a broad-spectrum antibiotic used in laboratory settings. It functions as a protein synthesis inhibitor, targeting the 30S subunit of bacterial ribosomes, which plays a crucial role in the translation of genetic information into proteins. Streptomycin is commonly used in microbiological research and applications that require selective inhibition of bacterial growth.
Sourced in United States, United Kingdom, Germany, Canada, Japan, Sweden, Austria, Morocco, Switzerland, Australia, Belgium, Italy, Netherlands, China, France, Denmark, Norway, Hungary, Malaysia, Israel, Finland, Spain
MATLAB is a high-performance programming language and numerical computing environment used for scientific and engineering calculations, data analysis, and visualization. It provides a comprehensive set of tools for solving complex mathematical and computational problems.
Sourced in United States, China, United Kingdom, Germany, France, Australia, Canada, Japan, Italy, Switzerland, Belgium, Austria, Spain, Israel, New Zealand, Ireland, Denmark, India, Poland, Sweden, Argentina, Netherlands, Brazil, Macao, Singapore, Sao Tome and Principe, Cameroon, Hong Kong, Portugal, Morocco, Hungary, Finland, Puerto Rico, Holy See (Vatican City State), Gabon, Bulgaria, Norway, Jamaica
DMEM (Dulbecco's Modified Eagle's Medium) is a cell culture medium formulated to support the growth and maintenance of a variety of cell types, including mammalian cells. It provides essential nutrients, amino acids, vitamins, and other components necessary for cell proliferation and survival in an in vitro environment.
Sourced in United States, China, United Kingdom, Germany, Australia, Japan, Canada, Italy, France, Switzerland, New Zealand, Brazil, Belgium, India, Spain, Israel, Austria, Poland, Ireland, Sweden, Macao, Netherlands, Denmark, Cameroon, Singapore, Portugal, Argentina, Holy See (Vatican City State), Morocco, Uruguay, Mexico, Thailand, Sao Tome and Principe, Hungary, Panama, Hong Kong, Norway, United Arab Emirates, Czechia, Russian Federation, Chile, Moldova, Republic of, Gabon, Palestine, State of, Saudi Arabia, Senegal
Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
Sourced in United States, United Kingdom, Jersey, Germany, Japan, Switzerland, Canada, Australia, France
Collagenase type II is an enzyme used in cell and tissue culture applications. It is responsible for the breakdown of collagen, a structural protein found in the extracellular matrix. This enzyme is commonly used to facilitate the dissociation of cells from tissues during cell isolation and harvesting procedures.
Sourced in United States, China, United Kingdom, Germany, Canada, France, Australia, Japan, India, Spain, Switzerland, Israel, Italy, Belgium, Austria, New Zealand, Brazil, Argentina, Denmark, Ireland, Singapore, Egypt
Dulbecco's modified Eagle's medium (DMEM) is a cell culture medium commonly used for the in vitro cultivation of various cell types. It provides a balanced salt solution, amino acids, vitamins, and other nutrients required for cell growth and maintenance.
Sourced in United States, Germany, United Kingdom, France, China, Switzerland, Australia, Austria, Italy, Japan, Canada, Belgium, Brazil, Spain, New Zealand, Netherlands, Denmark, Israel, Sweden, Ireland, Poland, Holy See (Vatican City State), Bulgaria, Argentina, Hungary, Macao
Fetal calf serum is a nutrient-rich cell culture supplement derived from the blood of bovine fetuses. It provides a complex mixture of proteins, growth factors, and other components that support the growth and proliferation of cells in in vitro cell culture systems.
Sourced in United States
Sodium persulfate (SPS) is an inorganic chemical compound with the formula Na2S2O8. It is a white crystalline solid that functions as an oxidizing agent and initiator in various chemical processes.
Chondrex offers a set of 5 monoclonal antibodies. These antibodies are laboratory tools used to detect and quantify specific target molecules in research applications.

More about "Metacarpophalangeal Joint"

The Metacarpophalangeal Joint (MCP), also known as the knuckle joint, is a critical component of hand function.
This joint, located between the metacarpal bone and the proximal phalanx of each finger, enables a wide range of dexterous movements essential for daily activities.
Proper understanding and evaluation of the MCP joint is crucial for assessing overall hand function and diagnosing related musculoskeletal conditions.
The MCP joint allows for flexion, extension, abduction, and adduction of the fingers, granting us the ability to grasp, pinch, and manipulate objects with precision.
Understanding the anatomy and biomechanics of the MCP joint is vital for fields such as orthopedics, physical therapy, and occupational therapy.
Researchers studying the MCP joint may utilize techniques like Penicillin, Streptomycin, MATLAB, DMEM, FBS, Collagenase type II, and monoclonal antibodies to investigate joint function, pathologies, and potential treatments.
PubCompare.ai's AI-driven protocol comparison tool can help optimize MCP joint research by identifying the most effective products, methods, and protocols from the literature, preprints, and patents.
This can enhance the reproducibility and accuracy of MCP joint studies, ultimately advancing our understanding and management of hand function and related musculoskeletal conditions.
Whether you're a researcher, clinician, or healthcare professional, PubCompare.ai can be a valuable resource for your Metacarpophalangeal Joint studies.