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Cell

Indispensable Cellular Techniques: Protocols for Advancing Groundbreaking Research

3T3 Cells
3 438 protocols
3T3 Cells: A Versatile Tool for Scientific Exploration

3T3 cells, derived from mouse embryonic fibroblasts, are a widely used cell line in a variety of scientific experiments.
Their ease of culture, stable growth characteristics, and well-documented behavior make them a reliable and versatile model system for studying cellular processes, testing drug candidates, and investigating wound healing and tissue engineering applications.
As a commonly employed cell line in cell biology, toxicology, and regenerative medicine research, 3T3 cells continue to play a crucial role in advancing our scientific understanding across multiple disciplines.
3T3-L1 Cells
10 333 protocols
3T3-L1 cells are a widely used in vitro model for studying adipocyte (fat cell) differentiation and function.
These mouse-derived fibroblast cells have the unique ability to undergo adipogenesis, making them a valuable tool for researchers investigating obesity, diabetes, and related metabolic disorders. 3T3-L1 cells are commonly employed in a variety of applications, including drug screening, signaling pathway analysis, and the evaluation of adipogenic and lipogenic factors, providing crucial insights into the complex mechanisms underlying adipocyte biology.
A549 Cells
39 662 protocols
A549 cells are a widely used human alveolar basal epithelial cell line derived from a lung adenocarcinoma.
These cells are highly relevant in various scientific experiments, particularly in the fields of respiratory biology, cancer research, and drug development.
Due to their ability to recapitulate key features of the human alveolar epithelium, A549 cells are commonly employed as a model system for studying lung physiology, pathogenesis of respiratory diseases, and evaluating the efficacy and safety of pharmaceutical compounds targeting the lungs.
Acinar Cell
1 720 protocols
Acinar cells are a crucial component in various scientific experiments and research protocols.
These specialized exocrine cells, found in organs like the pancreas and salivary glands, play a vital role in the production and secretion of essential enzymes, hormones, and other biomolecules.
Researchers often utilize acinar cell cultures or tissue samples to study cellular function, signaling pathways, and the impact of various stimuli or therapeutic agents on their behavior, making them a valuable model for exploring physiological processes and disease mechanisms.
Adipocytes
26 033 protocols
Adipocytes, or fat cells, play a crucial role in a wide range of scientific experiments.
As the primary storage site for excess energy in the form of triglycerides, these cells are highly relevant in studies exploring metabolism, obesity, and related metabolic disorders.
Researchers often utilize adipocytes to investigate processes such as lipogenesis, lipolysis, and adipokine secretion, which are essential for understanding the complex interplay between adipose tissue and overall health. [Keywords: Adipocytes, fat cells, metabolism, obesity, triglycerides, lipogenesis, lipolysis, adipokines, research protocols.]
Adipocytes, Brown
1 140 protocols
Adipocytes, brown (also known as brown fat cells or brown adipose tissue) are a specialized type of fat cell that play a crucial role in energy metabolism and thermogenesis.
These cells are of great interest in scientific research due to their potential applications in areas such as obesity, diabetes, and energy regulation.
Researchers commonly utilize Adipocytes, Brown in experiments exploring novel therapeutic interventions, metabolic processes, and the underlying mechanisms that govern energy homeostasis, making them a valuable tool for advancing our understanding of these important physiological and pathological conditions.
Adipose-Derived Mesenchymal Stem Cells
547 protocols
Adipose-Derived Mesenchymal Stem Cells (ADMSCs) are a versatile source of multipotent stem cells that can be readily isolated from adipose tissue.
These ADMSC-based protocols have gained significant attention in the scientific community due to their potential applications in a wide range of research areas, including tissue engineering, regenerative medicine, and cell-based therapies.
Researchers working with ADMSCs can leverage their capacity for self-renewal, multi-lineage differentiation, and immunomodulatory properties to explore novel therapeutic approaches, develop innovative cell culture techniques, and advance our understanding of stem cell biology.
Allogeneic Cells
1 241 protocols
Allogeneic cells, also known as allogenic cells, refer to cells derived from a genetically distinct individual of the same species.
These cells are widely used in scientific research and medical applications, including cell therapy, tissue engineering, and organ transplantation.
Allogeneic cell-based protocols offer valuable insights into immune responses, tissue regeneration, and the potential for personalized treatments, making them a crucial tool in the arsenal of researchers exploring cellular and regenerative therapies.
Alveolar Epithelial Cells
2 885 protocols
Alveolar Epithelial Cells: A Vital Player in Respiratory Research

Alveolar epithelial cells (AECs) are a crucial component of the lung's alveolar structure, playing a pivotal role in gas exchange and pulmonary homeostasis.
These cells are extensively utilized in scientific experiments, particularly in the fields of respiratory biology, toxicology, and pharmaceutical development.
Researchers often employ AECs to investigate lung function, model diseases, and evaluate the efficacy and safety of respiratory therapeutics, making them a versatile and indispensable tool in various respiratory research protocols.
Amacrine Cells
595 protocols
Amacrine cells are a type of retinal interneuron that play a crucial role in visual information processing.
These cells are known to be involved in various visual functions, including light adaptation, motion detection, and contrast enhancement.
Researchers often study amacrine cells in the context of retinal physiology, neurobiology, and visual neuroscience, using techniques such as electrophysiology, immunohistochemistry, and imaging to investigate their structure, function, and connectivity within the retinal circuit.
Understanding the role of amacrine cells is essential for developing a comprehensive understanding of visual information processing and can have important implications for the diagnosis and treatment of retinal disorders.
Antibody-Secreting Cells
664 protocols
Antibody-Secreting Cells (ASCs) are a critical component in many immunological research protocols, playing a pivotal role in the study of humoral immune responses.
These specialized B cells, also known as plasma cells, are responsible for the secretion of antibodies, making them invaluable for investigating antibody production, antigen-specific immune responses, and vaccine efficacy.
ASCs are frequently utilized in a range of scientific experiments, including immunization studies, disease pathogenesis research, and the development of novel therapeutic antibodies.
Antigen-Presenting Cells
4 192 protocols
Antigen-Presenting Cells (APCs) are a crucial component in immunological research, playing a vital role in the activation and regulation of the adaptive immune response.
These specialized cells, which include dendritic cells, macrophages, and B cells, are responsible for capturing, processing, and presenting antigens to T cells, making them an essential tool in various scientific experiments.
Researchers commonly utilize APCs to study immune cell interactions, vaccine development, and the underlying mechanisms of autoimmune disorders, leveraging their unique capabilities to uncover valuable insights and advance scientific knowledge.
Astrocytes
35 500 protocols
Astrocytes, the star-shaped glial cells in the central nervous system, play a pivotal role in various scientific experiments.
These versatile cells are crucial for maintaining the homeostatic environment of the brain, modulating synaptic transmission, and supporting neuronal function.
Researchers often utilize astrocytes in studies related to neurodegenerative diseases, neuroinflammation, and neural development, making them an integral component of many experimental protocols in the fields of neuroscience, cell biology, and biomedical research.
Atypical Squamous Cells of Undetermined Significance
1 688 protocols
Atypical Squamous Cells of Undetermined Significance (ASCUS) is a cytological diagnosis that plays a crucial role in scientific research, particularly in the fields of gynecology and oncology.
This ambiguous classification of cervical cells is widely utilized in experimental protocols to investigate the underlying mechanisms and potential implications of this cytological abnormality.
Researchers often employ ASCUS as a starting point to explore the complex interplay between cellular changes, human papillomavirus (HPV) infection, and the development of precancerous or cancerous conditions, contributing to a deeper understanding of cervical cancer pathogenesis and the development of effective screening and prevention strategies.
Auditory Hair Cell
2 854 protocols
Auditory hair cells are the mechanoreceptors responsible for the initial transduction of sound waves into electrical signals in the inner ear.
As a fundamental component of the auditory system, these specialized cells are a critical focus in various scientific experiments investigating hearing, sound perception, and the underlying mechanisms of auditory function.
Researchers often utilize auditory hair cells in protocols exploring areas such as ototoxicity, hair cell regeneration, and the development and testing of hearing-related therapies and interventions.
B-Lymphocytes
53 813 protocols
B-Lymphocytes, also known as B-cells, play a crucial role in the adaptive immune response and are frequently studied in scientific research.
These specialized white blood cells are responsible for producing antibodies, which recognize and neutralize foreign pathogens, making them a valuable target for various experimental protocols.
From investigating humoral immunity and vaccine development to understanding autoimmune disorders and cancer immunotherapy, B-Lymphocytes are a key component in a wide range of biomedical and immunological research applications.
Basophils
5 155 protocols
Basophils, a unique type of granulocyte, play a crucial role in various scientific experiments and research applications.
As the least abundant circulating white blood cells, basophils are increasingly recognized for their involvement in inflammatory responses, allergic reactions, and immune system regulation.
Researchers often utilize basophil-focused protocols to study the underlying mechanisms of these processes, paving the way for advancements in fields like immunology, allergy research, and drug development.
Blood Cells
26 131 protocols
Blood cells, also known as hematocytes, are essential components in various scientific experiments and research protocols.
These cellular elements, including red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes), play crucial roles in a wide range of applications, from immunological studies and drug development to disease diagnosis and monitoring.
Researchers across diverse fields, such as hematology, pathology, and pharmacology, frequently utilize blood cell analysis and manipulation techniques to gain valuable insights and advance their scientific endeavors.
Blood Platelets
56 982 protocols
Blood platelets, also known as thrombocytes, play a crucial role in the field of scientific research.
These small, disc-shaped cell fragments are instrumental in the process of blood clotting and are widely used in a variety of experimental protocols, including studies on hemostasis, thrombosis, and platelet function.
Researchers often utilize blood platelets to investigate their behavior, signaling pathways, and interactions with other blood components, making them a valuable tool in understanding the complex mechanisms underlying various cardiovascular and hematological disorders.
Bone Marrow Cells
30 557 protocols
Bone Marrow Cells (BMCs) play a crucial role in a wide range of scientific experiments, making them a valuable research tool for scientists across various fields.
These multipotent cells, derived from the bone marrow, can differentiate into a diverse array of cell types, including hematopoietic, mesenchymal, and endothelial cells, making them highly versatile in applications such as regenerative medicine, stem cell therapy, and tissue engineering.
Researchers studying bone marrow transplantation, cellular therapy, and the mechanisms of hematopoiesis and bone remodeling often rely on BMCs as a key component of their experimental protocols.
Bone Marrow Mesenchymal Stem Cells
1 689 protocols
Bone Marrow Mesenchymal Stem Cells (BM-MSCs) are a versatile and widely-used cell type in scientific research, known for their ability to differentiate into various cell lineages.
These multipotent stem cells, derived from the bone marrow, have become a valuable tool for researchers exploring regenerative medicine, tissue engineering, and cellular therapy applications.
BM-MSCs are commonly utilized in pre-clinical studies focused on areas such as bone and cartilage repair, wound healing, and the management of inflammatory and autoimmune disorders, making them a crucial component of many experimental protocols.
Bone Marrow Stromal Cells
1 700 protocols
Bone Marrow Stromal Cells (BMSCs) are a versatile population of multipotent progenitor cells found within the bone marrow niche, making them a valuable resource for a wide range of scientific research applications.
Widely used in cell and tissue engineering studies, BMSCs have demonstrated the capacity to differentiate into various cell lineages, including osteoblasts, chondrocytes, and adipocytes, making them an attractive choice for regenerative medicine, stem cell therapy, and tissue repair protocols.
Researchers across diverse fields, from immunology to oncology, frequently employ BMSCs as model systems to investigate cellular interactions, signaling pathways, and the potential therapeutic applications of this dynamic cell population.
Burst-Forming Units, Erythroid
975 protocols
Burst-Forming Units, Erythroid (BFU-E) are a crucial component in the study of erythropoiesis, the process of red blood cell production.
These hematopoietic progenitor cells are widely employed in scientific experiments exploring the regulation, differentiation, and maturation of the erythroid lineage.
Researchers often utilize BFU-E assays to investigate factors influencing erythroid development, such as the effects of cytokines, growth factors, and pharmacological agents, making them a valuable tool in hematological and stem cell research.
Caco-2 Cells
14 791 protocols
Caco-2 cells are a widely used in vitro model system derived from human colorectal adenocarcinoma cells.
These cells are particularly relevant for evaluating the intestinal permeability and absorption of various compounds, including drugs, nutrients, and other molecules, making them a valuable tool in pharmaceutical, nutraceutical, and toxicological research.
Caco-2 cells are commonly employed in studies related to drug development, formulation optimization, and the assessment of oral bioavailability, demonstrating their versatility and importance in the field of biomedical research.
Cancer Stem Cells
1 540 protocols
Cancer Stem Cells (CSCs) are a subpopulation of cells within tumors that possess the ability to self-renew, differentiate, and drive tumor initiation, progression, and recurrence.
Understanding the unique properties and behavior of CSCs is crucial for developing novel cancer therapies and improving patient outcomes.
Researchers commonly utilize CSC-focused protocols in areas such as drug screening, targeted therapy development, and the elucidation of the underlying molecular mechanisms that govern CSC biology, making this an essential area of study in the field of oncology.
Cancer-Associated Fibroblasts
1 047 protocols
Cancer-Associated Fibroblasts (CAFs) are an essential component of the tumor microenvironment, playing a crucial role in cancer progression and therapeutic response.
These specialized cells secrete growth factors, cytokines, and extracellular matrix proteins that can profoundly influence tumor growth, invasion, and angiogenesis.
Researchers often utilize CAFs in various experimental models, such as co-culture systems and in vivo xenograft studies, to investigate their impact on cancer cell behavior, evaluate novel therapeutic strategies, and unravel the complex signaling pathways that govern the interplay between CAFs and cancer cells.
CD4 Positive T Lymphocytes
59 905 protocols
CD4 Positive T Lymphocytes are a crucial subset of T cells that play a pivotal role in the adaptive immune response.
These helper T cells, known for their expression of the CD4 surface marker, are widely utilized in various scientific experiments, including studies on immune function, disease pathogenesis, and the development of immunotherapies.
Researchers often investigate the dynamics, phenotypic characteristics, and functional capacities of CD4 Positive T Lymphocytes to gain insights into the complex mechanisms underlying immune regulation and to explore their potential therapeutic applications.
CD8-Positive T-Lymphocytes
43 458 protocols
CD8-positive T-lymphocytes, also known as cytotoxic T cells, play a crucial role in cellular immunity and are widely used in various research protocols.
These specialized immune cells can recognize and eliminate virus-infected or cancerous cells, making them valuable tools for studying immune responses, vaccine development, and immunotherapies.
Researchers often employ techniques such as flow cytometry, cell sorting, and functional assays to isolate, characterize, and analyze CD8-positive T-lymphocytes, providing insights into their role in health, disease, and potential therapeutic interventions.
Cell Line, Transformed
2 811 protocols
Cell Line, Transformed" is a widely used research tool in the scientific community, offering invaluable insights across various experimental domains.
This immortalized cell line, derived from a transformed cell, is renowned for its ability to proliferate indefinitely, making it a versatile model for studying cellular processes, evaluating drug efficacy, and investigating disease mechanisms.
Researchers often employ "Cell Line, Transformed" in a broad range of applications, including cell biology, biochemistry, and cancer research, owing to its reliable and consistent performance in controlled laboratory settings.
Cell Line, Tumor
8 817 protocols
Cell Line, Tumor is a critical tool in scientific research, particularly in the fields of oncology, cell biology, and drug development.
This immortalized cell line, derived from a specific type of tumor, provides researchers with a standardized and reproducible model to investigate cancer mechanisms, test therapeutic interventions, and study cellular processes.
Cell Line, Tumor is widely employed in a variety of experimental settings, from studying tumor growth and metastasis to evaluating the efficacy and toxicity of potential anti-cancer drugs, making it a valuable resource for researchers seeking to advance our understanding and treatment of cancer.