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Indispensable Cellular Techniques: Protocols for Advancing Groundbreaking Research

Enterocytes
2 070 protocols
Enterocytes, the absorptive epithelial cells lining the small intestine, play a crucial role in various scientific experiments.
As a key component of the intestinal barrier, these cells are widely utilized to study nutrient absorption, drug permeability, and intestinal physiology.
Researchers often employ in vitro models involving enterocytes, such as Caco-2 cell lines, to investigate the mechanisms underlying intestinal transport, the effects of dietary compounds, and the potential for oral drug delivery, making them a valuable tool in the field of gastrointestinal research.
Eosinophil
16 204 protocols
Eosinophils, a type of white blood cell, play a crucial role in numerous scientific experiments and research protocols.
These granulocytes are often employed as key indicators of inflammatory processes, allergy responses, and certain disease states, making them invaluable in a wide range of experimental settings, from immunology and hematology to drug development and toxicology studies.
Researchers frequently utilize eosinophil counts, function assays, and isolation techniques to gain deeper insights into the underlying mechanisms of various physiological and pathological conditions, ultimately contributing to our understanding of human health and the advancement of scientific knowledge.
Epidermal Cells
4 955 protocols
Epidermal cells, the outermost layer of the skin, play a crucial role in a wide range of scientific experiments.
These keratinocytes serve as valuable models for studying skin biology, wound healing, and the effects of various compounds on the epidermis.
Researchers frequently utilize epidermal cell cultures, three-dimensional skin models, and in vivo approaches to investigate topics such as skin barrier function, inflammation, and the efficacy of dermatological treatments, making these cells an essential tool for a diverse range of scientific disciplines.
Epithelial Cells
58 913 protocols
Epithelial cells are a crucial component in many scientific experiments, serving as essential building blocks for various tissue models and in vitro systems.
As the primary cell type found lining organs, glands, and body cavities, epithelial cells are widely utilized in research protocols involving topics such as tissue engineering, drug delivery, and disease modeling.
Researchers often employ epithelial cell cultures to study cell-cell interactions, barrier function, and cellular responses to environmental stimuli, making them a valuable tool for advancing our understanding of physiological and pathological processes.
Epithelioid Cells
1 509 protocols
Epithelioid cells, a specialized type of macrophage, play a pivotal role in various scientific experiments and research applications.
These cells, characterized by their epithelial-like appearance and functional properties, are widely utilized in immunological studies, tissue engineering, and disease modeling.
Researchers often employ Epithelioid cells to investigate inflammatory responses, granuloma formation, and the intricate interactions between the immune system and other physiological processes, making them a crucial component in many experimental protocols across diverse scientific disciplines.
Erythroblasts
1 460 protocols
Erythroblasts, the precursor cells of red blood cells, play a vital role in various scientific experiments.
These immature red blood cells are commonly used in research protocols to study hematopoiesis, erythropoiesis, and related cellular processes.
Erythroblasts are particularly relevant in experiments investigating anemia, hemoglobin disorders, and the development and differentiation of the erythroid lineage, making them a valuable tool for researchers in the fields of hematology, cell biology, and regenerative medicine.
Erythrocytes
110 501 protocols
Erythrocytes, commonly known as red blood cells, play a crucial role in numerous scientific experiments and research protocols.
These specialized cells, responsible for oxygen transport throughout the body, are widely utilized in various biomedical applications, including hematological studies, drug screening, and membrane permeability assessments.
Researchers often employ erythrocytes as model systems to investigate cellular processes, assess the efficacy of therapeutic interventions, and explore the underlying mechanisms of various physiological and pathological conditions.
Erythroid Cells
1 373 protocols
Erythroid cells, also known as red blood cells or erythrocytes, are a crucial component in various scientific experiments and research protocols.
These specialized cells play a vital role in oxygen transport and are widely utilized as model systems in studies related to hematology, stem cell biology, and cellular metabolism.
Researchers frequently employ erythroid cells to investigate cellular differentiation, hemoglobin production, and the effects of various treatments or genetic manipulations on red blood cell function, making them a valuable tool for advancing our understanding of both normal and pathological blood-related processes.
Eukaryotic Cells
8 427 protocols
Eukaryotic cells, with their complex and well-defined internal structures, are a fundamental component of numerous scientific experiments and research protocols.
These cells, which include those found in plants, animals, and fungi, are widely used in various applications, such as cell culture, gene expression studies, drug screening, and cellular assays.
Understanding the unique characteristics and functions of eukaryotic cells is crucial for researchers seeking to unravel the intricacies of biological processes, develop novel therapeutic strategies, and advance our understanding of the living world.
Feeder Cells
5 096 protocols
Feeder Cells: A Crucial Component in Scientific Experiments

Feeder cells, also known as "supporting cells," play a pivotal role in a wide range of scientific experiments, particularly in the field of stem cell research and cell culture protocols.
These specialized cells provide a nurturing microenvironment, offering essential growth factors and support structures that are crucial for the successful cultivation and maintenance of various cell types, including pluripotent stem cells and sensitive primary cell lines.
Researchers across diverse disciplines, from regenerative medicine to drug discovery, routinely employ feeder cells to create optimal conditions for their experimental models, highlighting their indispensable contribution to advancements in scientific knowledge and innovation.
Fibroblasts
110 491 protocols
Fibroblasts are a versatile cell type that play a crucial role in various scientific experiments.
As the most common connective tissue cells in the body, fibroblasts have become a valuable tool for researchers investigating wound healing, extracellular matrix production, and cellular signaling pathways.
From cell culture studies to tissue engineering applications, fibroblasts offer a wealth of opportunities for scientists to explore the underlying mechanisms of health and disease.
Researchers looking to incorporate fibroblasts into their experimental protocols can find a wealth of relevant information and best practices in the scientific literature.
Foam Cells
1 589 protocols
Foam Cells are a crucial component in various scientific experiments, particularly in the fields of cardiovascular research and atherosclerosis studies.
These lipid-laden macrophages play a central role in the development and progression of atherosclerotic plaques, making them a valuable model for investigating the underlying mechanisms of cardiovascular disease.
Foam Cells are widely utilized in protocols examining lipid metabolism, inflammatory pathways, and the efficacy of potential therapeutic interventions, providing valuable insights into the pathogenesis and management of atherosclerosis.
GABAergic Neurons
1 697 protocols
GABAergic neurons, a crucial subtype of inhibitory interneurons, play a pivotal role in regulating neural excitability and network activity within the central nervous system.
These GABA-producing cells are widely utilized in a variety of neuroscience research protocols, including studies on neuronal circuit dynamics, synaptic transmission, and the modulation of brain function.
Researchers often employ techniques like optogenetics, electrophysiology, and pharmacological manipulations to investigate the functional properties and contributions of GABAergic neurons in both physiological and pathological conditions, making them a valuable target for understanding brain biology and developing potential therapeutic interventions.
Gametes
4 416 protocols
Gametes, the specialized reproductive cells in multicellular organisms, play a crucial role in various scientific experiments and research protocols.
These haploid cells, containing half the normal chromosome set, are essential for processes like fertilization, genetic recombination, and the study of reproductive biology.
Researchers often utilize gametes, such as sperm and eggs, to investigate topics ranging from developmental biology and assisted reproductive technologies to evolutionary mechanisms and genetic engineering applications.
Gametophytes
913 protocols
Gametophytes, the haploid, multicellular reproductive structures of plants, play a crucial role in various scientific experiments and research protocols.
As the stage in the plant life cycle where genetic recombination occurs, gametophytes offer valuable insights into plant biology, development, and genetics.
Researchers frequently utilize gametophytes to investigate topics ranging from plant reproduction and evolution to environmental responses and stress tolerance, making them a versatile and essential component in a wide range of plant-based studies.
Gastrin-Secreting Cells
9 161 protocols
Gastrin-secreting cells, also known as G-cells, play a crucial role in the regulation of gastric acid secretion.
These specialized cells, located primarily in the antrum of the stomach, are an essential part of many research protocols exploring the mechanisms of digestive function and gastrointestinal disorders.
Researchers often utilize G-cell models to investigate the impact of various stimuli, such as nutrients, hormones, and pharmacological agents, on gastrin release and its downstream effects on stomach acid production, providing valuable insights into the complex processes of nutrient absorption and digestive health.
Germ Cells
20 800 protocols
Germ cells are the specialized cells responsible for the transmission of genetic information from one generation to the next.
These cells play a crucial role in various scientific experiments, including assisted reproductive technologies, stem cell research, and developmental biology studies.
Researchers often utilize germ cell-based protocols to investigate topics such as gamete formation, fertilization, and early embryonic development, making them a valuable tool for both fundamental and applied scientific research.
Germ Line
21 848 protocols
Germ line, the genetic material passed down from parents to offspring, plays a crucial role in scientific experiments and research.
Understanding the germ line is essential for studies involving heredity, genetic modifications, and the investigation of inherited traits and disorders.
Researchers commonly utilize germ line analysis techniques, such as genome sequencing and transgenic models, to explore fundamental biological processes, develop novel therapies, and advance our understanding of human and animal genetics.
Giant Cells
2 943 protocols
Giant Cells, also known as multinucleated cells, are a unique and fascinating cell type that have gained significant attention in the scientific community.
These specialized cells, which can contain multiple nuclei within a single cytoplasm, play crucial roles in various biological processes, making them a valuable subject of study in numerous research applications.
From tissue regeneration and immune response analysis to disease modeling and drug development, the investigation of Giant Cells has become an integral part of many scientific protocols, offering researchers valuable insights into complex cellular mechanisms and their potential therapeutic implications.
Goblet Cells
4 796 protocols
Goblet Cells: Versatile Gatekeepers in Scientific Exploration
Goblet cells, known for their essential role in mucus production, have become a crucial focus in various scientific experiments.
These specialized epithelial cells serve as valuable models for investigating mucosal barrier function, immune responses, and the pathogenesis of various respiratory and gastrointestinal disorders.
Researchers frequently employ goblet cell analysis, quantification, and manipulation techniques to elucidate the mechanisms underlying health and disease processes, making them a widely-utilized tool in both basic and translational research.
Granulocyte
11 275 protocols
Granulocytes, a type of white blood cell, play a crucial role in immune response and inflammation.
These specialized cells, which include neutrophils, eosinophils, and basophils, are widely used in scientific experiments to study various aspects of the immune system, from cell signaling to phagocytic activity.
Granulocytes are particularly relevant in immunology, hematology, and cell biology research, where they are commonly employed to investigate topics such as host-pathogen interactions, cell-mediated immunity, and the mechanisms of inflammatory disorders.
Granulocyte-Macrophage Colony Forming Units
557 protocols
Granulocyte-Macrophage Colony Forming Units (GM-CFU) are a crucial tool in hematology and stem cell research.
These in vitro assays measure the ability of hematopoietic progenitor cells to differentiate into granulocytes and macrophages, providing valuable insights into the development and function of the myeloid lineage.
GM-CFU assays are widely used to evaluate the potency of stem cell populations, test the effects of growth factors or small molecules on myeloid differentiation, and investigate the impact of genetic or environmental factors on hematopoiesis, making them an indispensable technique in a range of scientific experiments.
Granulosa Cell
3 776 protocols
Granulosa cells are a crucial component in scientific research, particularly in studies related to reproductive biology and endocrinology.
These somatic cells, which surround the oocyte (egg) within the ovarian follicle, play a vital role in the regulation of ovarian function and steroidogenesis.
Researchers frequently utilize granulosa cells in a wide range of applications, including in vitro fertilization (IVF) studies, hormone receptor analysis, and the investigation of ovarian pathologies such as polycystic ovary syndrome (PCOS).
Grid Cells
10 957 protocols
Grid Cells: A Fundamental Component in Spatial Navigation Research

Grid cells, located in the entorhinal cortex, play a crucial role in the neural representation of spatial information, forming a hexagonal grid-like pattern that aids in the animal's ability to navigate its environment.
Researchers studying spatial cognition and memory often utilize grid cell recordings as a key experimental approach, as these unique neuronal representations provide valuable insights into the brain's mechanisms for encoding and processing spatial data.
The investigation of grid cell properties and their interaction with other spatial coding systems, such as place cells, has become a central focus in the field of cognitive neuroscience and has numerous applications in understanding the neural basis of spatial navigation and memory.
HaCaT Cells
9 893 protocols
HaCaT cells, a well-established immortalized human keratinocyte cell line, have become a widely used model system in various scientific disciplines, including dermatology, cell biology, and toxicology research.
As a standardized and well-characterized human skin cell line, HaCaT cells offer researchers a reliable and reproducible platform to investigate skin-related processes, such as barrier function, wound healing, and the effects of topical compounds or environmental stressors.
The versatility and ease of use of HaCaT cells make them a valuable tool for researchers seeking to develop and validate experimental protocols involving human skin cell-based in vitro models.
Haploid Cell
940 protocols
Haploid cells play a crucial role in various scientific experiments and research protocols.
These cells, containing a single set of chromosomes, are widely used in areas such as genetics, cell biology, and biotechnology.
From analyzing meiosis and studying genetic inheritance to developing haploid cell lines for genetic manipulation, the applications of haploid cells are diverse and essential for advancing our understanding of fundamental biological processes.
HCT116 Cells
19 452 protocols
HCT116 Cells: A Versatile Model in Cancer Research

HCT116 cells, a widely used human colorectal carcinoma cell line, have become a pivotal tool in cancer research and drug development.
Derived from a male patient with colorectal carcinoma, these cells possess a unique genetic profile and exhibit characteristics akin to various cancer hallmarks, making them a valuable in vitro model for studying cellular signaling pathways, evaluating anticancer drug efficacy, and investigating novel therapeutic strategies.
HCT116 cells are commonly employed in a range of scientific experiments, from cell proliferation assays and apoptosis analyses to three-dimensional (3D) cell culture and xenograft studies, providing researchers with a reliable and clinically relevant platform to advance our understanding of colorectal cancer.
HEK293 Cells
125 806 protocols
HEK293 cells are a widely used human embryonic kidney cell line that has become a workhorse in scientific research.
These versatile cells are renowned for their ability to express recombinant proteins, making them a popular choice for studying gene expression, protein function, and drug development applications.
Researchers frequently leverage the HEK293 cell system to investigate a diverse range of biological processes, from cell signaling and receptor trafficking to viral infection and vaccine development.
HeLa Cells
100 170 protocols
HeLa cells, derived from the cervical cancer cells of Henrietta Lacks, are one of the most widely used and studied cell lines in scientific research.
Due to their robust growth, immortality, and consistent genetic profile, HeLa cells have become an essential tool for a wide range of scientific experiments, from drug development and testing to the study of cellular mechanisms and disease modeling.
Researchers across various fields, including cell biology, pharmacology, and cancer research, rely on HeLa cells to provide reliable and reproducible data, making them a cornerstone of many experimental protocols.
Helper-Inducer T-Lymphocyte
3 248 protocols
Helper-Inducer T-Lymphocytes, also known as CD4+ T cells, play a crucial role in coordinating and orchestrating immune responses in a wide range of scientific experiments.
These T-cell subsets are instrumental in activating and supporting other immune cells, making them a valuable tool for researchers studying topics such as immunology, inflammation, and infectious disease.
Incorporating Helper-Inducer T-Lymphocytes into experimental protocols can provide valuable insights into the complex dynamics of the immune system and offer potential avenues for therapeutic interventions.