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Cell

Indispensable Cellular Techniques: Protocols for Advancing Groundbreaking Research

Pericytes
4 436 protocols
Pericytes are a specialized type of cells found in the walls of small blood vessels, including capillaries and venules.
These cells play a crucial role in the regulation of blood flow, maintenance of the blood-brain barrier, and modulation of the immune response.
Researchers often utilize pericytes in various scientific experiments, such as studies on angiogenesis, neurovascular coupling, and the pathogenesis of neurological disorders, making them a valuable target for investigating the intricacies of the vascular and neurological systems.
Peripheral Blood Stem Cells
1 280 protocols
Peripheral Blood Stem Cells (PBSCs) have become a crucial component in various scientific experiments and clinical applications.
These unique, multipotent cells, derived from the peripheral blood, offer remarkable potential for regenerative medicine, cell-based therapies, and disease modeling.
Researchers investigating hematopoiesis, stem cell biology, and cellular therapies often utilize PBSCs as a valuable resource, leveraging their versatility and accessibility to advance their projects and drive scientific discoveries forward.
Phagocytes
6 415 protocols
Phagocytes are crucial cellular components in various scientific experiments and research settings.
These specialized immune cells play a vital role in engulfing and digesting harmful pathogens, cellular debris, and foreign matter, making them a valuable tool for understanding immune system function, inflammation, and host-pathogen interactions.
Researchers frequently employ phagocytes, such as macrophages and neutrophils, in experimental protocols involving immune response analysis, drug screening, and the study of cellular processes, underscoring the importance of these cells in advancing our understanding of biological systems.
Photoreceptor Cells
5 876 protocols
Photoreceptor Cells play a crucial role in a wide range of scientific experiments, making them an essential component in many research protocols.
These specialized cells, responsible for the initial detection of light, have applications spanning from vision research and circadian rhythm studies to optical neuroscience and photobiology.
Researchers investigating topics such as phototransduction, retinal function, or light-sensitive signaling pathways often rely on the use of Photoreceptor Cells to gain valuable insights and advance their scientific understanding.
Place Cells
10 940 protocols
Place Cells are a type of neuron found in the hippocampus, a brain region crucial for spatial navigation and memory formation.
These specialized cells fire in response to an animal's location within its environment, serving as a neural representation of spatial information.
Place Cells have become an invaluable tool in neuroscience research, enabling scientists to study the neural mechanisms underlying cognitive processes like spatial learning, memory, and navigation, with applications ranging from studies of rodent behavior to investigations of human spatial cognition and disorders affecting spatial processing.
Plant Cells
2 428 protocols
Plant cells are the fundamental building blocks of plant life and a crucial component in a wide range of scientific experiments.
Understanding the structure and function of plant cells is essential for researchers investigating topics such as plant biology, agricultural science, and environmental studies.
From studying cell division and growth to analyzing plant responses to environmental stress, plant cell research protocols provide valuable insights that can drive advancements in fields ranging from food security to sustainable biofuel production.
Plasma Cells
8 830 protocols
Plasma cells play a crucial role in various scientific experiments, particularly in immunology and antibody research.
These terminally differentiated B cells are responsible for the production and secretion of large quantities of antibodies, making them a valuable tool for studying the humoral immune response.
Researchers commonly utilize plasma cells in applications such as monoclonal antibody generation, vaccine development, and the assessment of antigen-specific immune responses, making them an essential component in many experimental protocols aimed at advancing our understanding of the immune system.
Plasmacytoid Dendritic Cells
746 protocols
Plasmacytoid Dendritic Cells (pDCs) are a specialized subset of dendritic cells that play a crucial role in immune system regulation and antiviral responses.
Researchers often utilize pDCs in various experimental protocols, such as studies on type I interferon production, antigen presentation, and the modulation of T-cell and B-cell responses.
Understanding the unique functions and characteristics of pDCs is essential for developing novel immunotherapies, vaccine strategies, and disease-specific research involving these specialized immune cells.
Pluripotent Stem Cells
1 569 protocols
Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), have become invaluable tools in scientific research.
These versatile cells possess the remarkable ability to differentiate into a wide range of cell types, making them highly relevant for a variety of applications, such as disease modeling, drug screening, tissue engineering, and regenerative medicine.
Researchers often utilize protocols involving the culture, maintenance, and directed differentiation of PSCs to explore fundamental biology, develop novel therapies, and advance our understanding of human health and disease.
Podocytes
5 681 protocols
Podocytes are a specialized type of glomerular epithelial cells that play a crucial role in the filtration barrier of the kidney.
These highly complex cells are of great interest in nephrology research, as their structural and functional integrity is essential for maintaining proper kidney function.
Researchers often utilize podocyte-focused experiments to investigate the pathogenesis of various kidney diseases, evaluate the efficacy of potential therapeutic interventions, and gain deeper insights into the underlying mechanisms governing glomerular filtration and renal homeostasis.
Polar Bodies
2 853 protocols
Polar bodies are small, non-viable cells produced during the meiotic cell division of oocytes (egg cells) in many species.
They play a crucial role in the process of oocyte maturation and are often used as a valuable marker in various scientific experiments and research protocols.
Analyzing the presence, number, and morphology of polar bodies can provide insights into the developmental status of oocytes, making them a widely-used tool in areas such as assisted reproductive technologies, embryology, and stem cell research.
Pre-B Lymphocytes
1 341 protocols
Pre-B Lymphocytes are a crucial cell type in immunology research, serving as an intermediate stage in the development of mature B cells.
These immature B cells play a pivotal role in understanding B cell differentiation and the immune response, making them a valuable subject of study in a wide range of experimental protocols.
Researchers often investigate the properties, signaling pathways, and regulatory mechanisms of Pre-B Lymphocytes to gain insights into B cell ontogeny and the pathogenesis of B cell-related disorders.
Pro-B Lymphocytes
1 091 protocols
Pro-B Lymphocytes are a crucial cell type in immunological research, playing a pivotal role in the early stages of B-cell development.
These precursor B cells are often the subject of scientific experiments investigating hematopoiesis, B-cell differentiation, and immune system function.
Researchers frequently utilize pro-B lymphocyte cultures, flow cytometry, and gene expression analysis to study the mechanisms underlying B-cell maturation, antibody production, and immune responses, making this cell type a valuable tool in a wide range of immunology and hematology protocols.
Promyelocytes
593 protocols
Promyelocytes are a crucial early stage of myeloid cell development, playing a vital role in various scientific experiments.
As precursors to mature granulocytes, promyelocytes are often used in research protocols to study myelopoiesis, investigate cellular differentiation pathways, and analyze the effects of different stimuli on hematopoietic stem cell maturation.
Researchers frequently utilize promyelocyte cell lines or isolate primary promyelocytes from bone marrow or peripheral blood samples to uncover insights into immune system function, leukemogenesis, and the underlying mechanisms of myeloid disorders.
Protoplasts
11 579 protocols
Protoplasts are plant-derived cellular structures that have had their cell walls removed, revealing the underlying cell membrane and cytoplasm.
This unique preparation offers researchers a versatile tool for a range of scientific applications, from gene delivery and genetic engineering to the study of plant cell biology and biochemistry.
As a crucial component in many plant-based experimental protocols, understanding the properties and uses of protoplasts can be invaluable for researchers working in fields such as plant molecular biology, cell culture, and biotechnology.
Purkinje Cells
1 992 protocols
Purkinje cells, the distinctive and complex neurons found in the cerebellar cortex, have become a crucial subject of interest for neuroscience researchers.
These large, GABAergic cells play a vital role in the coordination of movement, motor learning, and sensory processing, making them a valuable target for studies exploring the neural mechanisms underlying various neurological and cognitive functions.
Researchers often utilize Purkinje cell-specific techniques, such as immunohistochemistry, electrophysiology, and optogenetics, to investigate their structure, function, and connectivity within the broader cerebellar network, with applications ranging from understanding fundamental principles of neural circuit organization to developing therapeutic interventions for neurological disorders.
Pyramidal Cells
9 270 protocols
Pyramidal cells are a crucial neuronal subtype found in the cerebral cortex, hippocampus, and other brain regions.
These distinctive, pyramid-shaped neurons play a central role in various scientific experiments, particularly in the fields of neuroscience, neurophysiology, and neuroanatomy.
Researchers frequently utilize pyramidal cells as model systems to investigate neuronal structure, function, synaptic plasticity, and the underlying mechanisms of cognitive processes, such as memory formation, information processing, and neural circuit dynamics.
RAW 264.7 Cells
29 250 protocols
RAW 264.7 Cells: A Versatile Tool in Scientific Exploration.
RAW 264.7 cells, a murine macrophage cell line, are a widely used in vitro model in immunological and inflammatory research.
Owing to their rapid growth, ease of maintenance, and well-characterized responses to various stimuli, RAW 264.7 cells have become a go-to choice for investigating mechanisms of immune function, cytokine production, and the effects of potential therapeutic compounds on macrophage biology.
Regulatory T-Lymphocytes
9 326 protocols
Regulatory T-Lymphocytes (Tregs) are a specialized subpopulation of T cells that play a crucial role in maintaining immune homeostasis and preventing autoimmune disorders.
These cells are pivotal in modulating immune responses and have become a subject of intense research interest in various scientific fields, including immunology, oncology, and transplantation biology.
Researchers commonly utilize Tregs in experimental protocols to investigate their mechanisms of action, study their role in disease pathogenesis, and develop novel therapeutic strategies that harness their immunoregulatory properties.
Reticulocytes
5 264 protocols
Reticulocytes are immature red blood cells that play a crucial role in various scientific experiments and research protocols.
As a key indicator of erythropoiesis (red blood cell production), reticulocyte counts are commonly used to assess the body's response to anemia, monitor the effectiveness of treatments, and evaluate the impact of interventions on the hematopoietic system.
Researchers across disciplines, from hematology and oncology to sports science and toxicology, frequently incorporate reticulocyte analysis into their experimental designs to gain insights into the dynamic processes of red blood cell production and turnover.
Retinal Cone
44 542 protocols
Retinal Cones are a crucial component of the human visual system, playing a vital role in color vision and day-time visual acuity.
These specialized photoreceptor cells are commonly utilized in various scientific experiments, ranging from studies on visual perception and color processing to investigations of retinal function and disease.
Researchers across disciplines, from neuroscience and ophthalmology to biology and vision science, frequently incorporate the analysis of retinal cones in their experimental protocols to better understand the complexities of the human visual system and its underlying mechanisms.
Retinal Ganglion Cells
1 499 protocols
Retinal Ganglion Cells (RGCs) are a critical component of the visual system, as they serve as the primary output neurons of the retina.
These specialized cells play a pivotal role in various scientific experiments, particularly in the fields of neuroscience, ophthalmology, and vision research.
RGCs are commonly used to study neural signaling, visual processing, and the impact of various treatments or interventions on the visual pathway, making them a valuable tool for researchers exploring the intricacies of the visual system.
Rod Photoreceptors
11 700 protocols
Rod photoreceptors are a crucial component of the visual system, responsible for mediating low-light and peripheral vision.
In scientific experiments, rod photoreceptors are often studied to understand their role in various visual processes, such as dark adaptation, night vision, and retinal function.
Researchers commonly employ techniques like electroretinography, calcium imaging, and optogenetics to investigate the properties and behaviors of rod photoreceptors, which have wide-ranging applications in fields like ophthalmology, neuroscience, and vision research.
Satellite Cell, Muscle
2 418 protocols
Satellite cells are a crucial component in muscle biology research, serving as the primary stem cell population responsible for muscle regeneration and growth.
These quiescent cells, found in close association with mature muscle fibers, can be activated in response to various stimuli, such as muscle injury or exercise, and subsequently proliferate and differentiate to repair or expand the muscle tissue.
Analyzing the behavior and functions of satellite cells is central to understanding muscle development, adaptation, and the underlying mechanisms of muscle-related diseases and disorders, making them a valuable target for a wide range of scientific experiments and clinical applications.
Schwann Cells
2 642 protocols
Schwann Cells are a critical component in the peripheral nervous system, playing a vital role in the support and maintenance of nerve fibers.
As a key cell type in various neuroscience and regenerative medicine research protocols, Schwann Cells are commonly utilized for studying nerve regeneration, myelination, and the development of neurodegenerative disease models.
Researchers frequently employ Schwann Cell cultures, co-culture systems, and in vivo models to explore a wide range of applications, from understanding the cellular mechanisms underlying nerve function to developing innovative therapies for neurological disorders.
Sertoli Cells
1 791 protocols
Sertoli Cells: Crucial Regulators in Reproductive Research
Sertoli cells play a pivotal role in male reproductive biology, making them a crucial component in various scientific experiments.
As the "nurse" cells of the testes, Sertoli cells support and nurture germ cells, influencing spermatogenesis and maintaining the blood-testis barrier.
Researchers commonly utilize Sertoli cell cultures, tissue samples, and in vivo models to investigate topics ranging from male infertility and testicular function to the development and differentiation of the male reproductive system.
Sf21 Cells
1 230 protocols
Sf21 Cells, derived from the ovarian cells of the fall armyworm Spodoptera frugiperda, are a widely used tool in molecular biology and biotechnology research.
These insect-derived cells are particularly valuable for the expression and production of recombinant proteins, as they offer efficient post-translational modifications, high protein yields, and ease of culture compared to other eukaryotic cell lines.
Sf21 Cells are commonly employed in various applications, including protein engineering, vaccine development, and the study of virus-host interactions, making them an essential component of many scientific protocols and experiments.
Sf9 Cells
8 926 protocols
Sf9 cells, a commonly used insect cell line derived from the ovarian tissue of the fall armyworm (Spodoptera frugiperda), have become a versatile tool in the world of scientific research.
These cells are widely employed for the expression of recombinant proteins, making them a crucial component in numerous experimental protocols, including protein production, vaccine development, and baculovirus-mediated gene delivery systems.
Sf9 cells' ability to perform post-translational modifications, coupled with their relatively easy maintenance and scalable culture, have solidified their position as a preferred choice for researchers exploring various applications in the fields of molecular biology, biochemistry, and biotechnology.
Skeletal Myocytes
11 195 protocols
Skeletal myocytes, the contractile cells that make up our skeletal muscles, are a fundamental component in numerous scientific experiments.
These highly specialized cells play a crucial role in the study of muscle physiology, neuromuscular function, and cellular metabolism, making them a valuable model system for researchers investigating topics such as muscle development, exercise performance, and muscular disorders.
Skeletal myocytes are widely used in various experimental protocols, including cell culture-based assays, tissue engineering, and animal studies, to elucidate the underlying mechanisms governing muscle structure, function, and adaptation.
Somatostatin-Secreting Cells
21 492 protocols
Somatostatin-Secreting Cells: Versatile Regulators in Scientific Investigations

Somatostatin-secreting cells, also known as delta cells, play a crucial role in various scientific experiments, making them a valuable subject of study.
These specialized cells are known for their ability to secrete the peptide hormone somatostatin, which acts as a regulator of growth hormone, insulin, and other endocrine functions.
Researchers commonly utilize Somatostatin-Secreting Cells in studies related to hormone regulation, metabolic processes, and the development of targeted therapies for conditions like acromegaly, diabetes, and neuroendocrine tumors.