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A Fibers

A Fibers: A type of nerve fiber that transmits sensory information from the periphery to the central nervous system.
These myelinated fibers have a relatively large diameter and conduct impulses rapidly, mediating the sense of touch and proprioception.
Researchers can leverage PubCompare.ai's cutting-edge protocol comparison tool to effortlessly locate the best protocols for studying A Fibers from literature, preprints, and patents, enabling more reproducible and accurate investigations that drive scientific breakthroughs.

Most cited protocols related to «A Fibers»

In additional to expert evaluation, T1-weighted images were used to conduct a qualitative comparison of the termination locations of the fiber tracks. The T1-weighted images were linearly registered to the DSI space by minimizing the mutual information. The T1-weighted images were then also segmented using SPM8 (Wellcome Trust Centre for Neuroimaging, UK), and the segmentation result was used to render the cortical surface. The tractography was overlapped by the rendered cortical surface to examine whether the termination locations of the fiber tracks were in good agreement with the gyral folding. The linear registration and cortical surface rendering were conducted using a built-in function provided by DSI Studio. The cortical surface was presented along with the fiber tracks to examine whether the termination locations of the tracks matched the gyral folding.
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Publication 2013
A Fibers Cortex, Cerebral Fibrosis

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Publication 2011
A Fibers Capillaries Carbon Cortex, Cerebral Rattus Urethane
AFQ uses a three-step procedure to identify 18 major fiber tracts in an individual's brain. The procedure is based on a combination of the methods described by Hua et al. [59] (link) and Zhang et al. [60] (link): (1) fiber tractography, (2) waypoint region-of-interest (ROI)-based fiber tract segmentation and (3) fiber tract refinement based on a probabilistic fiber tract atlas. Figure 8 depicts the AFQ analysis pipeline.
Step one, fiber tractography (Figure 8, panel 1): By default this step estimates fiber tracts using a deterministic streamlines tracking algorithm (STT) [8] (link), [9] (link) with a fourth-order Runge–Kutta path integration method and 1-mm fixed-step size. The tracking algorithm is seeded with a white matter mask defined as all the voxels with a fractional anisotropy (FA) value greater than 0.3. A continuous tensor field is estimated with trilinear interpolation of the tensor elements. Starting from initial seed points within the white matter mask, the path integration procedure traces streamlines in both directions along the principal diffusion axes. Individual streamline integration is terminated using two standard criteria: tracking is halted if (1) the FA estimated at the current position is below 0.2 and (2) the minimum angle between the last path segment and next step direction is greater than 30°. This tracking procedure produces a candidate database of fibers for the whole-brain that can then be segmented into anatomically defined fascicles. Note that this step can be done with different fiber orientation estimation methods (tensor, spherical harmonic etc.) and different tractography algorithms.
Step two, fiber tract segmentation (Figure 8, panel 2) is done based on the waypoint ROI procedure described in Wakana et al. [17] (link). In this procedure fibers are assigned to a particular fiber group if they pass through two waypoint ROIs that define the trajectory of the fascicle. The ROIs are defined in locations that isolate the central portion of the tract where the fibers are coherently bundled together and before they begin diverging towards cortex. Each waypoint ROI was drawn on a group-average DTI data set in MNI space based on the anatomical prescriptions defined in Wakana et al. [17] (link). The ROIs are transformed into an individual's native space based on an estimated non-linear transformation to the MNI template space [57] (link). This step is equivalent to the procedure described in Zhang et al. [60] (link), however we use a non-linear transformation instead of a linear transformation. This segmentation procedure defines which fibers are candidates for assignment to a particular fiber group.
Step three, fiber tract refinement (Figure 8, panel 3) is accomplished by comparing each candidate fiber to fiber tract probability maps [59] (link). Hua et al. [59] (link) created fiber tract probability maps of major fascicles by manually segmenting and coregistering each fiber groups for 28 healthy adult subjects, and calculating for each voxel the proportion of subjects with a given tract in that voxel. We transform the fiber tract probability maps into an individual's native space. Then candidate fibers for a particular fiber group are assigned scores based on the probability values of the voxels they pass through. Candidate fibers that take aberrant trajectories through regions of low probability are discarded. Each fiber in the resulting fiber group passes through the two waypoint ROIs that define the central trajectory of the fascicle and also conform to the shape of the tracts as defined by the fiber tract probability maps.
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Publication 2012
Adult A Fibers Anisotropy Brain Cortex, Cerebral Diffusion Epistropheus Fibrosis Healthy Volunteers Microtubule-Associated Proteins One-Step dentin bonding system Prescriptions White Matter
The waypoint ROIs used to identify the fiber groups are defined in planes that are marked by distinct anatomical features and these planes represent equivalent anatomical locations across subjects. The locations of the ROIs isolate the central trajectory of the fascicles. Even though the cortical endpoints of a fascicle typically vary across subjects, the central portion, bounded by the ROIs is generally consistent across individuals. In this report we quantify the diffusion properties of the fiber group along this central portion of the fascicle by clipping each fiber in the fiber group to the portion that spans between the two waypoint ROIs (Figure 8, panel 5) and resampling each fiber to 100 equally spaced nodes. The AFQ software includes options to calculate Tract Profiles for the full tract length or for the region between the defining ROIs. There are benefits to analyzing the full tract length however, it is important to recognize that the distal portions of the tract may not be in register across subjects. Analysis of the full Tract Profile may require additional coregistration procedures.
Diffusion properties are calculated at each node of each fiber using spline interpolation of the diffusion properties: fractional anisotropy FA, mean diffusivity (MD), radial diffusivity (RD) and axial diffusivity (AD). Properties are summarized at each node by taking a weighted average of the diffusion properties at that node on each fiber (Figure 8, panel 6). A fiber's contribution to the average is weighted by the probability that the fiber is a member of the fascicle. This probability is calculated based on the fiber's Mahalanobis distance from the fiber tract core. For example fibers traveling at the core of the fascicle are weighted heavily as these fibers are likely to represent a pure measurement of the tract. Further from the core of the tract diffusion measurements are likely to reflect a mix of white matter and gray matter or white matter and cerebral spinal fluid or white matter from other tracts. The admixing of multiple tissue types within a voxel is known as partial voluming and will bias diffusion measurements. Hence a fiber that diverges from the tract core will not contribute substantially to the tract summary. We summarize each fiber group with a vector of 100 values representing the diffusion properties sampled at equidistant locations along the central portion of the tract. We call this the Tract Profile.
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Publication 2012
A Fibers Anisotropy Cerebrospinal Fluid Cloning Vectors Cortex, Cerebral Diffusion Fibrosis Gray Matter Histocompatibility Testing White Matter
The set of ground truth long-range fiber bundles was designed to cover the whole human brain and features many of the relevant spatial configurations, such as crossing, kissing, twisting and fanning fibers, thus representing the morphology of the major known in vivo fiber bundles. The process to obtain these bundles consisted of three steps. First, a whole-brain global tractography was performed on a high-quality in vivo diffusion-weighted image. Then, 25 major long-range bundles were manually extracted from the resulting tractogram. In the third step, these bundles were refined to obtain smooth and well-defined bundles. Each of these steps is detailed in the following paragraphs.
We chose one of the diffusion-weighted data sets included in the Q3 data release of the HCP39 (link), subject 100307, to perform whole-brain global fiber tractography52 , 68 (link). Among other customizations, the HCP scanners are equipped with a set of high-end gradient coils, enabling diffusion encoding gradient strengths of 100 mT m−1. By comparison, most standard magnetic resonance scanners feature gradient strengths of about 30 to 40 mT m−1. This hardware setup allows the acquisition of data sets featuring exceptionally high resolutions (1.25 mm isotropic, 270 gradient directions) while maintaining an excellent SNR. All data sets were corrected for head motion, eddy currents and susceptibility distortions and are, in general, of very high quality69 –73 (link). Detailed information regarding the employed imaging protocols as well as the data sets themselves may be found on http://humanconnectome.org.
Global fiber tractography was performed using MITK Diffusion74 (link) with the following parameters: 900,000,000 iterations, a particle length of 1 mm, a particle width of 0.1 mm, and a particle weight of 0.002. Furthermore, we repeated the tractography six times and combined the resulting whole-brain tractograms into one large data set consisting of over five million streamlines. The selected parameters provided for a very high sensitivity of the tractography method. The specificity of the resulting tractogram was of lesser concern since the tracts of interest were extracted manually in the second step.
Bundle segmentation was performed by an expert radiologist using manually placed inclusion and exclusion regions of interest (ROI). We followed the concepts introduced in ref. 40 for the ROI placement and fiber extraction. Twenty-five bundles were extracted, covering association, projection, and commissural fibers across the whole brain (Fig. 1): CC, left and right cingulum (Cg), Fornix (Fx), anterior commissure (CA), left and right optic radiation (OR), posterior commissure (CP), left and right inferior cerebellar peduncle (ICP), middle cerebellar peduncle (MCP), left and right superior cerebellar peduncle (SCP), left and right parieto-occipital pontine tract (POPT), left and right cortico-spinal tract (CST), left and right frontopontine tracts (FPT), left and right ILF, left and right UF, and left and right SLF. As mentioned in the “Discussion” section, the IFOF, the MdLF, as well as the middle and inferior temporal projections of the AF were not included.
After manual extraction, the individual long-range bundles were further refined to serve as ground truth for the image simulation as also shown in Fig. 1. The original extracted tracts featured a large number of prematurely ending fibers and the individual streamlines were not smooth. To obtain smooth tracts without prematurely ending fibers, we simulated a diffusion-weighted image from each original tract individually using Fiberfox (www.mitk.org33). Since no complex fiber configurations, such as crossings, were present in the individual tract images and no artifacts were simulated, it was possible to obtain very smooth and complete tracts from these images with a simple tensor-based streamline tractography. Supplementary Fig. 7 illustrates the result of this refining procedure on the left CST.
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Publication 2017
A-002 A Fibers Brain Cerebellum Diffusion Eye Fibrosis Fornix, Brain Head Homo sapiens Hypersensitivity Magnetic Resonance Imaging MT 100 Peduncles, Middle Cerebellar Pons Radiologist Radiotherapy Susceptibility, Disease

Most recents protocols related to «A Fibers»

Example 2

In some applications, an infrasonic sensor is desired, with a frequency response fl that extends to an arbitrarily low frequency, such as a tenth of hundredth of a Hertz. Such a sensor might be useful for detecting fluid flows associated with movement of objects, acoustic impulses, and the like. Such an application works according to the same principles as the sonic sensor applications, though the length of individual runs of fibers might have to be greater.

In addition, the voltage response of the electrode output to movements is proportional to the velocity of the fiber, and therefore one would typically expect that the velocity of movement of fluid particles at infrasonic frequencies would low, leading to low output voltages. However, in some applications, the fluid movement is macroscopic, and therefore velocities may be appreciable. For example, in wake detection applications, the amplitude may be quite robust.

Generally, low frequency sound is detected by sensors which are sensitive to pressure such as infrasound microphones and microbarometers. As pressure is a scaler, multiple sensors should be used to identify the source location. Meanwhile, due to the long wave length of low frequency sound, multiple sensors have to be aligned far away to distinguish the pressure difference so as to identify the source location. As velocity is a vector, sensing sound flow can be beneficial to source localization. There is no available flow sensor that can detect infrasound flow in a broad frequency range with a flat frequency response currently. However, as discussed above, thin fibers can follow the medium (air, water) movement with high velocity transfer ratio (approximate to 1 when the fiber diameter is in the range of nanoscale), from zero Hertz to tens of thousands Hertz. If a fiber is thin enough, it can follow the medium (air, water) movement nearly exactly. This provides an approach to detect low frequency sound flow directly and effectively, with flat frequency response in a broad frequency range. This provides an approach to detect low frequency sound flow directly. The fiber motion due to the medium flow can be transduced by various principles such as electrodynamic sensing of the movement of a conductive fiber within a magnetic field, capacitive sensing, optical sensing and so on. Application example based on electromagnetic transduction is given. It can detect sound flow with flat frequency response in a broad frequency range.

For the infrasound detection, this can be used to detect manmade and natural events such as nuclear explosion, volcanic explosion, severe storm, chemical explosion. For the source localization and identification, the fiber flow sensor can be applied to form a ranging system and noise control to find and identify the low frequency source. For the low frequency flow sensing, this can also be used to detect air flow distribution in buildings and transportations such as airplanes, land vehicles, and seafaring vessels.

The infrasound pressure sensors are sensitive to various environmental parameters such as pressure, temperature, moisture. Limited by the diaphragm of the pressure sensor, there is resonance. The fiber flow sensor avoids the key mentioned disadvantages above. The advantages include, for example: Sensing sound flow has inherent benefit to applications which require direction information, such as source localization. The fiber flow sensor is much cheaper to manufacture than the sound pressure sensor. Mechanically, the fiber can follow the medium movement exactly in a broad frequency range, from infrasound to ultrasound. If the fiber movement is transduced to the electric signal proportionally, for example using electromagnetic transduction, the flow sensor will have a flat frequency response in a broad frequency range. As the flow sensor is not sensitive to the pressure, it has a large dynamic range. As the fiber motion is not sensitive to temperature, the sensor is robust to temperature variation. The fiber flow sensor is not sensitive to moisture. The size of the flow sensor is small (though parallel arrays of fibers may consume volume). The fiber flow sensor can respond to the infrasound instantly.

Note that a flow sensor is, or would be, sensitive to wind. The sensor may also respond to inertial perturbances. For example, the pressure in the space will be responsive to acceleration of the frame. This will cause bulk fluid flows of a compressible fluid (e.g., a gas), resulting in signal output due to motion of the sensor, even without external waves. This can be advantages and disadvantages depends on the detailed applications. For example, it can be used to detect flow distribution in the buildings. If used to detect infrasound, the wind influence be overcome by using an effective wind noise reduction approach.

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Patent 2024
Acceleration Acoustics A Fibers Blast Injuries Blood Vessel Cloning Vectors Dietary Fiber Electric Conductivity Electricity Electromagnetics Fibrosis Magnetic Fields Movement Pressure Reading Frames Sound Sound Waves Toxic Epidermal Necrolysis Ultrasonics Vaginal Diaphragm Vibration Water Movements Wind

Example 1

In this example, calcium carbonate crystallization (CaCO3) is used to deposit calcium carbonate on synthetic fibers. Calcium carbonate crystals were formed by mixing a CaCl2) solution and a NaCO3 solution and adding the mixture to a suspension of BAROLIFT® fibers. The resulting precipitated calcium carbonate on the fibers was in the form of discrete calcite crystals that were sparsely distributed about the outer surface of the fibers.

The shear thinning behavior of the resulting fiber additives was tested against that of untreated BAROLIFT® fibers. Both types of fibers were added to BARAZAN® D PLUS™ (viscosifier/suspension agent, available from Halliburton Energy Services, Inc.) in a concentration of 1.2 wt. %, and the shear viscosity for each solution was tested at different shear rates. The viscosity profile was obtained using a coaxial cylinder geometry (bob-cup) on an MCR501 rheometer (available from Anton Paar). FIG. 2 is a plot 200 illustrating the shear viscosity 202 in pascal seconds (Pa·s) of each of the tested fluids taken as a function of shear rate (1/seconds) 204. A first trace 206 represents the measurements taken for the solution with untreated fibers, while a second trace 208 represents the measurements taken for the solution with the treated fibers (fibers with calcium carbonate grown thereon). As illustrated, the shear viscosity for the treated fibers 208 is higher than that for the untreated fibers 206 across a wide range of shear rates. These results indicate that the fiber additives with calcium carbonate coated thereon experience increased interactions between the fibers, thereby improving the shear thinning behavior of the suspension by preventing fiber alignment in shear.

Example 2

In this example, calcium carbonate crystallization (CaCO3) is used to deposit calcium carbonate on synthetic fibers after an acid treatment is performed on the fibers. The acid treatment increases the population of calcium carbonate crystals formed on the outer surface of the fibers. A suspension of BAROLIFT® fibers was treated with 1M NaOH solution for 2 hours. Then, calcium carbonate crystals were formed on the fiber surface by mixing a CaCl2 solution and a NaCO3 solution and adding the mixture to the fibers. The resulting precipitated calcium carbonate on the fibers was in the form of discrete calcite crystals that were more concentrated on the outer surface of the fibers, as compared to the fiber additives of Example 1.

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Patent 2024
Acids A Fibers Calcite Carbonate, Calcium Crystallization Fibrosis Viscosity
Not available on PMC !

Example 4

A verification study for dry content levels of the fibre composition of the invention is presented herein.

The physical-mechanical properties of the body, also referred to as volume-to-mass ratio, (cm3/g), tensile index (Nm/g), bursting index (KPam2/g) and tear index (mNm2/g) for different dry content (%) were analyzed.

The results obtained in this study are portrayed in FIGS. 34, 35, 36 and 37.

Through the results, it was concluded that there was a significant body, also referred to as volume-to-mass ratio, gain after 30% dry content and a loss of tensile strength after 30% dry content. Additionally, it was observed that the dry content did not significantly affect the tear strength. Regarding the bursting rate, no significant changes were observed between the dry content levels of 10, 20, 30, and 50%. Therefore, it is clear that redispersibility was achieved up to a maximum of 50% dry content.

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Patent 2024
A Fibers Debility Fibrosis Figs Human Body Physical Processes Tears
The bleached
pulp was oxidized at 1 wt % consistency, at pH 10, with 5 mmol of
NaClO as the spent oxidizer, and with 0.1 g of NaBr and 0.016 g of
TEMPO per gram of fiber as co-catalysts, as described in previous
works.30 (link),31 (link) The carboxyl content of the oxidized pulp,
once thoroughly washed with distilled water, accounted for 0.73 ±
0.01 mmol −COOH g–1, as estimated by Davidson’s
methylene blue adsorption method.32 (link) Its
intrinsic viscosity, measured by the capillary viscometer procedure
(TAPPI T 230 om-08),33 was 2.37 dL g–1. From the Mark–Houwink parameters for cellulose
in copper(II) ethylenediamine, as reported elsewhere,34 (link),35 (link) this corresponds to a degree of polymerization of 390.
Fibrillation
was carried out in a high-pressure homogenizer, NS1001L PANDA 2 K-GEA
(GEA Niro Soavi, Parma, Italy). A suspension of oxidized fibers was
passed three times at 300 bar, three times at 600 bar, and three times
at 900 bar. A 0.1 wt %, suspension of the resulting CNFs exhibited
transmittance at 600 nm of 68%.
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Publication 2023
Adsorption A Fibers Capillaries Copper Dental Pulp Ethylenediamines Fibrosis Polymerization Pressure Viscosity
Animals were implanted with an optic cannula (φ400 µm, 0.39 NA; F0618S04B2P, Kyocera) above the LC unilaterally (tip at 5.6 mm posterior and 0.9 mm lateral to the bregma, and 3.0 mm ventral from the brain surface). One day after the surgery, animals were habituated to experimenters’ hands for 30 s twice per day for at least 1 week. After animals were habituated, a fiber cannula of an animal was connected with an optic fiber cable (φ400 µm, 0.39 NA; M98L01, Thorlabs) with an interconnect (ADAL3, Thorlabs), attached to a light source (M470F3, Thorlabs). The animal was placed in one side of a two-chamber cage (11 cm in width, 13 cm in depth, and 14 cm in height/chamber) with different floor textures (metal mesh and smooth) and wall appearance (black–white stripes and white) and allowed to explore both sides of the chamber for 10 min (baseline ‘OFF’ session). Animal behavior was monitored by a USB camera (ELP-USBFHD05MT-KL36IR, Ailipu Technology). The position of the nose was identified by Deeplabcut-live49 (link) with a pre-trained dataset. After the baseline session, the animal was replaced into the home cage, and the duration in each chamber was instantly analyzed. A chamber in which the animal stayed for a longer duration was defined as the preferred chamber. The animal was then placed in the preferred chamber, and allowed to explore the two-chamber cage for 10 min (RT-PPT ‘ON’ session). During the RT-PPT session, continuous light illumination (470 nm, 50–60 µW at the tip of an optic cannula) was delivered while the animal’s nose was in the chamber opposite to the preferred chamber (i.e., non-preferred chamber). Light illumination was controlled via microcontrollers (Arduino Uno R3) and synchronized red LED light, which was not observable from the subject animal, was shown to the camera. After recording, the recorded videos were analyzed with Deeplabcut50 (link), 51 (link) offline and the time spent in each chamber was calculated.
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Publication 2023
A Fibers Animals Brain Cannula Eye Light Lighting Metals Nose Surgery, Day

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More about "A Fibers"

A Fibers, also known as Type Ia fibers or large myelinated fibers, are a type of nerve fiber that transmit sensory information from the periphery to the central nervous system.
These fibers have a relatively large diameter and are myelinated, enabling them to conduct impulses rapidly.
They are responsible for mediating the sense of touch and proprioception, providing us with the ability to feel and perceive the position and movement of our body parts.
Researchers can utilize a variety of tools and techniques to study A Fibers, including MATLAB for data analysis, USB2000 and USB4000 for spectroscopic measurements, Fiber Analyzers for fiber characterization, QE65000 for low-light detection, and LabVIEW for instrument control and automation.
Additionally, the Rose Bengal stain can be used to visualize A Fibers, while the Eclipse Ti microscope and PM100D power meter can aid in detailed observation and measurement.
To enhance the reproducibility and accuracy of A Fibers research, researchers can leverage the cutting-edge protocol comparison tool offered by PubCompare.ai.
This AI-driven platform empowers users to effortlessly locate the best protocols from literature, preprints, and patents, ensuring that their investigations are based on the most reliable and up-to-date methodologies.
By utilizing PubCompare.ai's protocol comparison tool, researchers can make informed decisions and drive scientific breakthroughs in the study of A Fibers.
The S-4800 scanning electron microscope can also be employed to examine the intricate structure and morphology of A Fibers, providing valuable insights into their anatomy and function.
By combining these advanced tools and techniques, researchers can gain a deeper understanding of the role of A Fibers in the sensory and proprioceptive systems, and unlock new avenues for therapeutic interventions and scientific discoveries.