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Amino Acid

Unravel the Fundamental Building Blocks: Amino Acid Protocols for Groundbreaking Research

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)
3 179 protocols
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000), commonly referred to as DSPE-mPEG2000, is a widely used lipid-based compound in scientific research and experimentation.
This amphiphilic molecule is particularly relevant for drug delivery, liposome formulation, and nanoparticle development due to its unique properties, such as its ability to enhance the solubility, stability, and circulation time of various therapeutic agents.
DSPE-mPEG2000 has become an indispensable tool for researchers working on innovative drug delivery systems, nanomedicine, and other cutting-edge biomedical applications.
1-Phosphatidylinositol 3-Kinase
2 226 protocols
1-Phosphatidylinositol 3-Kinase (PI3K) is a critical enzyme that plays a central role in various cellular processes, including cell growth, proliferation, and survival.
Researchers frequently utilize PI3K in their experimental protocols to investigate signal transduction pathways, cell signaling mechanisms, and the development and progression of diseases such as cancer, diabetes, and neurological disorders.
Understanding the function and regulation of PI3K is essential for developing targeted therapies and uncovering potential therapeutic targets, making it a valuable tool in the field of biomedical research.
14-3-3 Proteins
3 061 protocols
14-3-3 Proteins are a family of highly conserved regulatory proteins that play a crucial role in numerous cellular processes.
These versatile proteins are commonly utilized in a wide range of scientific experiments, including signal transduction studies, cell cycle regulation analysis, and protein-protein interaction investigations.
Researchers often employ 14-3-3 Proteins in various applications, such as immunoprecipitation, pull-down assays, and Western blotting, to uncover the mechanisms underlying complex biological pathways and cellular functions.
167-A
1 854 protocols
167-A" is a widely used chemical compound in various scientific experiments and research protocols.
This versatile molecule has garnered attention for its diverse applications, ranging from cell signaling studies to drug discovery processes.
Researchers across various disciplines, including biochemistry, pharmacology, and molecular biology, routinely incorporate 167-A into their experimental designs to investigate a wide range of biological phenomena, making it a valuable tool in the scientific community.
2',3'-Cyclic-Nucleotide Phosphodiesterases
969 protocols
2',3'-Cyclic-Nucleotide Phosphodiesterases (CNPDs) are a class of enzymes that play a crucial role in cellular signaling and regulation.
These enzymes are responsible for the hydrolysis of cyclic nucleotides, such as cAMP and cGMP, which are important second messengers in various biological processes.
Researchers often utilize CNPDs in a wide range of scientific experiments, from investigating signal transduction pathways to developing therapeutic interventions targeting these enzymes.
Understanding the function and regulation of CNPDs is essential for researchers exploring topics related to cell signaling, neuroscience, and drug discovery.
2-(N-cyclohexylamino)ethanesulfonic acid
1 547 protocols
2-(N-cyclohexylamino)ethanesulfonic acid, commonly referred to as CHES, is a widely used buffer compound in a variety of scientific experiments and research protocols.
This zwitterionic, biological buffer is particularly useful for maintaining optimal pH conditions in biochemical, cell-based, and enzyme-catalyzed reactions, making it a valuable tool for researchers studying protein structure, enzyme kinetics, and cellular processes.
Due to its versatility and effectiveness in a wide range of applications, CHES is a staple in many scientific laboratories, enabling researchers to precisely control the pH of their experimental systems and obtain reliable, reproducible results.
2-5A-dependent ribonuclease
1 551 protocols
2-5A-dependent ribonuclease (2-5A RNase) is a crucial enzyme that plays a vital role in various scientific experiments and research applications.
This enzyme is known for its ability to selectively degrade RNA, making it a valuable tool in molecular biology, gene expression studies, and RNA interference (RNAi) techniques.
Researchers often employ 2-5A RNase to investigate RNA dynamics, regulate gene expression, and develop novel therapeutic approaches targeting specific RNA molecules, making it a versatile and indispendable component in many research protocols.
26S proteasome
839 protocols
The 26S proteasome is a large, multi-subunit protein complex that plays a crucial role in the degradation of ubiquitinated proteins within eukaryotic cells.
This essential cellular machinery is a common target of investigation in a wide range of scientific experiments, including studies on protein turnover, cellular quality control, and the regulation of signal transduction pathways.
Researchers frequently utilize protocols involving the isolation, purification, and functional analysis of the 26S proteasome to better understand its diverse biological functions and potential implications in disease processes.
3'-nuclease
1 138 protocols
3'-nuclease, a crucial enzyme in molecular biology, plays a pivotal role in various scientific experiments.
This 3'-to-5' exonuclease activity is widely utilized in DNA sequencing, RNA processing, and DNA repair protocols, making it an indispensable tool for researchers studying gene expression, genomics, and nucleic acid metabolism.
Understanding the mechanisms and applications of 3'-nuclease is essential for designing effective experimental procedures and advancing our understanding of fundamental biological processes.
3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent
546 protocols
3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent (HMG-CoA reductase) is a crucial enzyme that plays a vital role in the cholesterol biosynthesis pathway.
This NADP-dependent enzyme catalyzes the rate-limiting step in the mevalonate pathway, making it a prime target for research related to lipid metabolism, cardiovascular diseases, and pharmacological interventions.
Researchers commonly employ HMG-CoA reductase assays, inhibitor screening, and expression studies to explore its regulatory mechanisms, potential therapeutic applications, and its overall importance in cellular processes.
3-nitrotyrosine
3 198 protocols
3-nitrotyrosine is a widely used biomarker in oxidative stress research.
This nitrated amino acid serves as an indicator of nitric oxide-mediated protein modifications, often associated with various pathological conditions, such as inflammation, neurodegeneration, and cardiovascular diseases.
The detection and quantification of 3-nitrotyrosine levels in biological samples, using techniques like ELISA, mass spectrometry, or immunohistochemistry, provide valuable insights into the oxidative environment and can inform the development of targeted therapeutic strategies.
5-Hydroxytryptophan
574 protocols
5-Hydroxytryptophan (5-HTP) is a widely studied compound in the field of neuroscience and pharmacology.
As a precursor to the neurotransmitter serotonin, 5-HTP has gained considerable attention for its potential applications in various scientific experiments, particularly those focused on mood regulation, sleep, and cognitive function.
Researchers often utilize 5-HTP in protocols aimed at exploring its effects on neurological and physiological processes, making it a valuable tool in the development of new therapeutic interventions and the understanding of the complex mechanisms underlying human behavior and well-being.
6-Aminocaproic Acid
1 848 protocols
6-Aminocaproic Acid (6-ACA) is a versatile compound with a wide range of applications in scientific research.
As a fibrinolytic inhibitor, 6-ACA plays a crucial role in various experimental protocols, particularly in studies involving blood coagulation, thrombosis, and hemostasis.
Researchers commonly utilize 6-Aminocaproic Acid to investigate the mechanisms of blood clot formation, assess the efficacy of anticoagulant therapies, and explore its potential as a therapeutic agent in conditions characterized by excessive bleeding or thrombotic events.
6-Phosphofructokinase
545 protocols
6-Phosphofructokinase (6PFK) is a critical enzyme in the glycolytic pathway, playing a pivotal role in the regulation of cellular energy metabolism.
This enzyme catalyzes the irreversible phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate, a key step in the conversion of glucose to ATP.
Researchers often utilize 6PFK assays and inhibition studies to investigate metabolic processes, signal transduction pathways, and the impact of various pharmacological agents on cellular bioenergetics in a wide range of experimental models, including cell culture, tissue samples, and animal studies.
A 144
2 082 protocols
A 144 is a widely-used compound in scientific research, particularly in the fields of neuroscience, pharmacology, and cell biology.
This versatile molecule has numerous applications, including as a receptor agonist, signal transduction modulator, and tool for investigating cellular pathways.
Researchers often employ A 144 in various experimental settings, such as in vitro studies, animal models, and drug discovery pipelines, to elucidate the underlying mechanisms of physiological and pathological processes.
A 145
1 624 protocols
A 145 is a widely studied compound in scientific research, particularly in the fields of pharmacology, neuroscience, and cell biology.
This versatile molecule has been employed in a variety of experimental settings, from investigating its effects on cellular signaling pathways to evaluating its potential therapeutic applications.
Researchers often utilize A 145 in protocols designed to elucidate its mechanisms of action, explore its interactions with other biomolecules, and assess its impacts on physiological processes, making it a valuable tool in the arsenal of scientific investigation.
A 336
618 protocols
A 336" is a widely used compound in scientific research, particularly in the fields of pharmacology, neuroscience, and cell biology.
This small molecule has proven to be a valuable tool in various experimental settings, serving as a selective inhibitor of a specific target or pathway.
Researchers often employ A 336 to investigate the mechanisms underlying cellular processes, drug-target interactions, and the modulation of signaling cascades, making it a versatile and indispensable component in many research protocols.
A 338
553 protocols
A 338" is a widely used compound in scientific research, particularly in the fields of pharmacology, neuroscience, and cellular biology.
As a selective agonist for the adenosine A3 receptor, A 338 has proven valuable in investigating the role of this receptor subtype in various physiological and pathological processes, such as inflammation, neuroprotection, and cancer.
Researchers frequently employ A 338 in experimental models to elucidate the underlying mechanisms and potential therapeutic applications related to the adenosine A3 receptor, making it a crucial tool in advancing our understanding of these complex biological systems.
A protein, mouse
334 786 protocols
A protein, mouse" is a critical tool in various scientific experiments, particularly in the fields of molecular biology, genetics, and developmental biology.
This versatile protein is widely used to study gene expression, signaling pathways, and cellular processes in a mammalian model system.
Researchers often employ "A protein, mouse" to investigate the underlying mechanisms of disease development, the effects of drug candidates, and the dynamics of cellular interactions, making it a valuable resource for a wide range of scientific inquiries.
A-A-1 antibiotic
29 405 protocols
A-A-1 antibiotic is a widely used compound in various scientific experiments due to its potent antimicrobial properties.
Researchers often utilize A-A-1 antibiotic in cell culture studies, antimicrobial resistance testing, and investigations of bacterial pathogenesis, making it a crucial tool in the field of microbiology and related disciplines.
Its versatility and effectiveness have made A-A-1 antibiotic a popular choice for researchers seeking to maintain sterile conditions, assess antimicrobial susceptibility, or explore the mechanisms underlying bacterial infections and responses.
Abatacept
1 399 protocols
Abatacept, a novel immunomodulatory agent, has gained significant attention in the scientific community for its potential applications in a wide range of research areas.
As a selective T-cell costimulation modulator, Abatacept has demonstrated efficacy in regulating immune responses, making it a valuable tool for researchers studying autoimmune disorders, transplantation, and inflammatory conditions.
Its unique mechanism of action and proven safety profile have led to its increasing use in preclinical and clinical research protocols, providing researchers with a robust and reliable therapeutic option to explore novel treatment strategies.
ABCA1 protein, human
3 382 protocols
The ABCA1 protein, human is a key player in the regulation of cellular cholesterol homeostasis and has garnered significant interest in the scientific community.
As a critical component of the reverse cholesterol transport pathway, the ABCA1 protein is widely studied in various research applications, including investigations of lipid metabolism, cardiovascular disease, and the development of therapeutic interventions targeting cholesterol imbalances.
Researchers often utilize ABCA1 protein, human in experimental protocols exploring cellular cholesterol efflux, lipid signaling pathways, and the molecular mechanisms underlying cholesterol regulation, making it a valuable tool for researchers in the fields of biochemistry, cell biology, and translational medicine.
ABCB1 protein, human
3 569 protocols
ABCB1 protein, also known as P-glycoprotein (P-gp), is a crucial multidrug efflux transporter expressed in various human tissues.
Its primary function is to regulate drug absorption, distribution, and elimination, making it a central player in pharmacokinetics and pharmacodynamics.
Researchers often utilize ABCB1 protein in experimental settings to investigate drug-drug interactions, evaluate the impact of genetic polymorphisms on drug responses, and develop strategies to modulate drug bioavailability and resistance, particularly in the fields of oncology, neurology, and personalized medicine.
ABCC1 protein, human
902 protocols
ABCC1 protein, also known as multidrug resistance-associated protein 1 (MRP1), is a critical component in various scientific experiments.
As a member of the ATP-binding cassette (ABC) transporter family, ABCC1 plays a pivotal role in the regulation of cellular efflux and drug resistance mechanisms, making it a valuable target for research in fields such as oncology, pharmacology, and toxicology.
Researchers often utilize ABCC1 protein, human in experimental protocols to investigate drug transport, explore therapeutic strategies, and understand the underlying mechanisms of multidrug resistance, crucial for advancing scientific knowledge and developing effective treatments.
ABCG1 protein, human
935 protocols
ABCG1 protein, human, is a crucial regulator of cellular cholesterol homeostasis and plays a significant role in the transport of cholesterol and other lipids.
This ATP-binding cassette (ABC) transporter is commonly utilized in research protocols involving the investigation of lipid metabolism, atherosclerosis, and related cardiovascular diseases.
Researchers frequently employ ABCG1 protein, human, in experimental settings such as cell-based assays, gene expression studies, and animal models to better understand its influence on cholesterol efflux, lipid regulation, and its potential as a therapeutic target.
ABI1 protein, human
3 717 protocols
ABI1 protein, human, is a crucial regulator of signal transduction pathways and is widely studied in various scientific experiments.
As a key component in abscisic acid (ABA) signaling, the ABI1 protein plays a vital role in plant stress response mechanisms, making it a valuable target for research on abiotic stress tolerance.
Researchers commonly utilize recombinant ABI1 protein, human, in cellular and molecular biology studies, including protein-protein interaction assays, enzyme activity analyses, and the development of ABA-responsive biosensors for agricultural and environmental applications.
ABI2 protein, human
1 225 protocols
ABI2 (Abl-interactor 2) protein is a key regulator of cell signaling pathways and is highly expressed in various human tissues.
This multifunctional protein plays a crucial role in processes like cell migration, actin cytoskeleton organization, and cell-cell adhesion, making it a valuable target for scientific research.
Protocols involving the analysis of ABI2 protein expression, localization, and interaction partners are widely used in cell biology, cancer research, and neuroscience studies to better understand its functional implications in human health and disease.
Ac-aspartyl-glutamyl-valyl-aspartyl-aminomethylcoumarin
810 protocols
Ac-aspartyl-glutamyl-valyl-aspartyl-aminomethylcoumarin, or AGVD-AMC, is a fluorogenic substrate commonly used in protease activity assays.
This tetrapeptide is specifically cleaved by caspases, a family of cysteine proteases involved in apoptosis and inflammation.
AGVD-AMC is a versatile tool for measuring caspase activity in cell-based experiments, enabling researchers to investigate the role of these enzymes in various biological processes and disease models.
ACACA protein, human
1 472 protocols
ACACA protein, human, is a crucial enzyme involved in the regulation of fatty acid biosynthesis, making it a valuable target for a wide range of scientific investigations.
This multifunctional protein plays a pivotal role in cellular energy metabolism and has been extensively studied in various research applications, including disease modeling, drug discovery, and metabolic pathway analysis.
Researchers commonly utilize ACACA protein, human, in experimental protocols focused on lipid homeostasis, metabolic disorders, and the development of novel therapeutics targeting energy-related pathways.
Accutase
20 744 protocols
Accutase is a versatile cell detachment solution widely used in cell biology research.
This enzyme-based reagent effectively dissociates adherent cells from culture surfaces, making it a crucial tool for various experimental procedures, such as cell passaging, cell counting, and cell-based assays.
Researchers commonly employ Accutase to maintain the viability and functionality of delicate cell types, including stem cells, primary cells, and sensitive cell lines, making it a valuable asset in stem cell research, regenerative medicine, and beyond.