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Silicone Elastomers

Silicone Elastomers are a class of synthetic polymers known for their unique physical properties, including flexibility, durability, and resistance to heat and chemicals.
These materials are widely used in various industries, such as medical devices, automotive components, and consumer products.
The PubCompare.ai platform leverages AI-driven technology to optimize research protocols and enhance reproducibility for Silicone Elastomers, enabling researchers to easily locate protocols from literature, pre-prints, and patents, and use AI-driven comparisons to identify the best protocols and products.
This cutting-edge tool improves research efficiency and reliabilty, helping scientists to make more informed decisions and accelerate the development of innovative Silicone Elastomer-based solutions.
Seach Silicone Elastmers now to discover how PubCompare.ai can transform your research approach.

Most cited protocols related to «Silicone Elastomers»

1
Virtual Reality System for Head-Restrained Mouse Electrophysiology
Cited 71 times
A virtual reality system was designed using an air-supported spherical treadmill for head-restrained mice19 (link) in combination with a projection-based visual display system20 (link), in which a toroidal screen presented an image from a projector via an angular amplification mirror21 (link). Custom software to control the virtual reality system was developed based on the Quake2 game engine. Rotations of the spherical treadmill, measured by an optical computer mouse, were used to update the visual display. Water-scheduled C57BL/6J mice (8–12 weeks old) were trained using operant conditioning to run from end-to-end of a virtual linear track (180 cm long) to obtain water rewards. For electrophysiology measurements, a small craniotomy (~0.5 mm diameter) was made centered over dorsal hippocampus (2.2 mm caudal, 1.7 lateral to bregma). The craniotomy was sealed with silicone grease and then covered with silicone elastomer to allow recordings across multiple days. Extracellular recordings were made using a glass electrode (filled with 0.5 M NaCl, ~2.5 MΩ pipette resistance) mounted on a micromanipulator positioned behind the mouse. Whole cell recordings were obtained using standard blind patch methods. Patch pipettes were pulled with a long taper (~100 μm diameter at 1 mm from the tip), to minimize damage to the overlying cortical tissue, and were mounted on a micromanipulator positioned outside the field of view. Firing rate maps were calculated for 80 spatial bins along the virtual track as the number of spikes in a bin divided by the time spent in that bin. Changes in baseline membrane potential in the place field were measured from membrane potential traces excluding spikes. Theta oscillations were analyzed following band-pass filtering (6–10 Hz) of the membrane potential recording using a linear phase finite impulse response filter.
Harvey C.D., Collman F., Dombeck D.A, & Tank D.W. (2009). Intracellular dynamics of hippocampal place cells during virtual navigation. Nature, 461(7266), 941-946.
Publication 2009
Cortex, Cerebral Craniotomy Head Membrane Potentials Mice, Inbred C57BL Microtubule-Associated Proteins Mus Seahorses Silicone Elastomers Silicones Sodium Chloride Strains Tissues Visually Impaired Persons
2
Cerebral Ischemia Induction and Assessment
Cited 14 times

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Publication 2009
Amputation Stumps Anesthesia Animals ARID1A protein, human Bears Blood Circulation Cerebral Ischemia Cerebrovascular Circulation Cranium External Carotid Arteries Internal Carotid Arteries Ischemia Isoflurane Locomotion Middle Cerebral Artery Mus Muscle Tissue Neck Operative Surgical Procedures Rectum Reperfusion Silicone Elastomers Sutures Tail Torso Upper Extremity Paresis
3
Qualitative Insights into the ASPIRE Trial
Cited 13 times
The ASPIRE trial design, population, procedures and primary findings have been previously published [16 (link),17 (link)]. Briefly, 2629 women were enrolled at 15 sites in Malawi, South Africa, Uganda and Zimbabwe, and were followed for at least 12 months from August 2012 to June 2015. Women were randomized (1 : 1 ratio) to receive a silicone elastomer matrix ring (outer diameter of 56 mm, cross-sectional diameter of 7.7 mm) containing 25 mg of dapivirine or a placebo ring. The qualitative component was conducted from February 2013 to June 2015 at six study sites, representing each trial country and three metropolitan areas of South Africa. A total of 214 ASPIRE trial participants were recruited into one of three interview modalities: single in-depth interview (IDI) or serial IDI (SIDI), or focus group discussion (FGD), with 280 interviews completed (Fig. 1). This combination of interview approaches was used to provide a variety of complementary perspectives. SIDI, used with randomly selected women and ‘special cases' chosen by site staff for their unique adherence experiences, allowed for exploration of temporal trends while building rapport between interviewer and interviewee. Single IDI were used to gather data from those who permanently discontinued ring use, most ofwhom were seroconverters. FGDs among randomly selected participants allowed for exploration of group norms and attitudes about ring use, as a complement to individual experiences.
Montgomery E.T., van der Straten A., Chitukuta M., Reddy K., Woeber K., Atujuna M., Bekker L.G., Etima J., Nakyanzi T., Mayo A.J., Katz A., Laborde N., Grossman C.I., Soto-Torres L., Palanee-Phillips T, & Baeten J.M. (2017). Acceptability and use of a dapivirine vaginal ring in a phase III trial. AIDS (London, England), 31(8), 1159-1167.
Publication 2017
A-214 Dapivirine Interviewers Placebos Silicone Elastomers Woman
4
Dapivirine Vaginal Ring for HIV Prevention
Cited 11 times
At enrollment, women were assigned in a 1:1 ratio, with the use of fixed-size block randomization, stratified according to site, to receive either a silicone elastomer vaginal matrix ring containing 25 mg of dapivirine or a placebo vaginal ring. Both the dapivirine and placebo rings were manufactured by QPharma under contract with the International Partnership for Microbicides. The dapivirine and placebo rings were indistinguishable, and with the exception of staff members at the central statistical and data management center, investigators and participants were unaware of the randomization assignments until completion of the trial. Women were taught how to insert and remove the vaginal ring and counseled to wear it for the entire month.
Women returned for monthly follow-up visits, which included HIV-1 serologic testing, safety monitoring, and individualized adherence counseling (Table S4 in the Supplementary Appendix). At each visit, a new ring was provided, and the ring that had been used during the previous month was collected. Women were tested monthly for pregnancy, and the study ring was withheld from women who became pregnant; they resumed use of the study ring when no longer pregnant or lactating. All participants received a package of HIV-1 prevention services, including counseling with respect to HIV-1 risk reduction, partner HIV-1 testing, treatment of sexually transmitted infections in participants and partners, and free condoms. (Details regarding the trial design are provided in the Supplementary Appendix.)
Baeten J.M., Palanee-Phillips T., Brown E.R., Schwartz K., Soto-Torres L.E., Govender V., Mgodi N.M., Kiweewa F.M., Nair G., Mhlanga F., Siva S., Bekker L.G., Jeenarain N., Gaffoor Z., Martinson F., Makanani B., Pather A., Naidoo L., Husnik M., Richardson B.A., Parikh U.M., Mellors J.W., Marzinke M.A., Hendrix C.W., van der Straten A., Ramjee G., Chirenje Z.M., Nakabiito C., Taha T.E., Jones J., Mayo A., Scheckter R., Berthiaume J., Livant E., Jacobson C., Ndase P., White R., Patterson K., Germuga D., Galaska B., Bunge K., Singh D., Szydlo D.W., Montgomery E.T., Mensch B.S., Torjesen K., Grossman C.I., Chakhtoura N., Nel A., Rosenberg Z., McGowan I, & Hillier S. (2016). Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women. The New England journal of medicine, 375(22), 2121-2132.
Publication 2016
Condoms Dapivirine HIV-1 Microbicides Placebos Pregnancy Safety Sexually Transmitted Diseases Silicone Elastomers Teaching Woman
5
Staging and Embryo Dissection
Cited 8 times

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Publication 2011
Dissection Embryo Hyperostosis, Diffuse Idiopathic Skeletal Silicone Elastomers Somites Streptococcal Infections

Most recents protocols related to «Silicone Elastomers»

1
Molded Silicone Pressure Sensitive Adhesive
Not available on PMC !

Example 3

Moulded Silicone Pressure Sensitive Adhesive Body:

Dow Corning 7-9800 A&B (mixing ration between A and Bis 1:1 by weight) were used for production of a PDMS based adhesive body. A mould having a triangular shape (each side of the triangular mould having a distance of 300 mm, the center part having a thickness of 0.5 mm and the edge having a thickness of 0.1 mm) was used. The components were thoroughly mixed and applied on a 50 μm cover layer of silicone rubber lining in the female part of a triangular mould and a male mould part was placed on top, said part lined with a low density polyethylene release liner. The adhesive was cured in an oven at 100 degree C. for 15 minutes. After curing the adhesive was punched out of the mould and a dent in the centre of the adhesive body device for embedment of an electronic sensing system was punched out.

US11864916B2. Three-dimensional adhesive device having a microelectronic system embedded therein (2024-01-09). Braemar Manufacturing, LLC [US]. Inventors: Susanne Holm Faarbaek [DK], Karsten Hoppe [DK], Peter Boman Samuelsen [DK], Jens Branebjerg [DK].
Full text: Click here
Patent 2024
A 300 Dental Cavity Liner Females Fungus, Filamentous Human Body Males Polyethylene, Low-Density Pressure Silicone Elastomers Silicones
2
Silicone Rubber Base Preparation
Not available on PMC !

Example 5

Both end dimethylvinylsiloxy-capped dimethylpolysiloxane having an average DOP of 1,800, 65 parts, was mixed with 40 parts of fumed silica having a BET specific surface area of 300 m2/g (Aerosil 300 by Nippon Aerosil Co.), 8 parts of hexamethyldisilazane, 0.1 part of 1,3-divinyl-1,1,3,3-tetramethyldisilazane (vinyl content 0.0116 mol/g), and 2.0 parts of water at 25° C. for 30 minutes. The mixture was heated at 150° C., continuously stirred for 3 hours, and cooled, obtaining a silicone rubber base. This silicone rubber base had a very high viscosity and was difficult to handle, with any further study interrupted.

TABLE 1
Comparative
ExampleExample
12341234
Hardness,2221232521232017
Durometer
type A
Tear strength, 2024201720221224
kN/m
Surface feeltack-tack-tack-tack-tack-tack-tack-tacky
(finger touch)freefreefreefreefreefreefree

TABLE 2
Comparative
Hexane ExampleExample
extraction test12341234
Extractives during 16.516.916.917.225.511013.518.0
first 7 hr, mg/inch2
Extractives during  1.8 3.6 2.9 3.213.0 45 1.9 6.5
succeeding
2 hr, mg/inch2

US11866583B2. Addition-curable liquid silicone rubber composition and molded silicone-rubber object (2024-01-09). SHIN-ETSU CHEMICAL CO., LTD. [JP]. Inventors: Nobu Kato [JP].
Full text: Click here
Patent 2024
1,3-butadiene A 300 Aerosil dimethicone Feelings Fingers hexamethyldisilazane n-hexane Polyvinyl Chloride Silicon Dioxide Silicone Elastomers Tears Touch Viscosity
3
In Vivo Calcium Imaging of Sensory Neurons
Adult mice expressing GCaMP3 (6–12 weeks, male and female) were anesthetized using ketamine (KETAVET; Zoetis; 100 mg/kg), xylazine (Rompun; Bayer; 15 mg/kg), and acepromazine (Elanco; 2.5 mg/kg). Depth of anesthesia was confirmed by pedal reflex and breathing rate. Animals were maintained at a constant body temperature of 37°C using a heated mat (VetTech). Lateral laminectomy was performed at spinal level L3–5. In brief, the skin was incised longitudinally, and the paravertebral muscles were cut to expose the vertebral column. Transverse and superior articular processes of the vertebrae were removed using OmniDrill 35 (WPI) and microdissection scissors. To obtain a clear image of the sensory neuron cell bodies in the ipsilateral dorsal root ganglion (DRG), the dura mater and the arachnoid membranes were carefully opened using microdissection forceps. Artificial spinal fluid (values are in mm: 120 NaCl, 3 KCl, 1.1 CaCl2, 10 glucose, 0.6 NaH2PO4, 0.8 MgSO4, and 18 NaHCO3, pH 7.4 with NaOH) was constantly perfused over the exposed DRG during the procedure to maintain tissue integrity. The animal was mounted onto a custom-made clamp attached to the vertebral column, rostral to the laminectomy. The trunk of the animal was slightly elevated to minimize interference caused by respiration. The DRG was isolated by coating with silicone elastomer.
Images were acquired using a Leica SP8 confocal microscope. A 10× dry, 0.4-N.A. objective with 2.2 mm working distanced was used, with image magnification of 0.75–3× optical zoom. GCaMP3 was excited using a 488 nm laser line (3–10% laser power). GCaMP was detected using a hybrid detector (60% gain). 512 × 512-pixel images were captured at a frame rate of 1.55 Hz, bidirectional scan speed of 800 Hz, and pixel dwell time of 2.44 μs.
Noxious and innocuous stimuli were applied to the left hindpaw, ipsilateral to the exposed DRG. For thermal stimuli, the ventral side of the paw was immersed with ice-water (nominally 0°C), acetone (100%) or water heated to 55°C using a Pasteur pipette. For delivery of precise temperature stimuli, a Peltier-controlled thermode (Medoc) was used. For mechanical stimuli, a pinch with serrated forceps was used. An interval of at least 30 s separated each stimulus application.
Iseppon F., Luiz A.P., Linley J.E, & Wood J.N. (2023). Pregabalin Silences Oxaliplatin-Activated Sensory Neurons to Relieve Cold Allodynia. eNeuro, 10(2), ENEURO.0395-22.2022.
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Publication 2023
Acepromazine Acetone Adult Anesthesia Animals Arachnoid Maters Bicarbonate, Sodium Body Image Cell Body Cell Respiration Cells Cerebrospinal Fluid Dura Mater Females Foot Forceps Ganglia, Spinal Glucose Hybrids Ice Joints Ketamine Laminectomy Males Mice, House Microdissection Microscopy, Confocal Muscle Tissue Obstetric Delivery Radionuclide Imaging Reading Frames Reflex Respiratory Rate Rompun Sensory Receptor Cells Silicone Elastomers Skin Sodium Chloride Sulfate, Magnesium Tissue, Membrane Tissues Vertebra Vertebral Column Vision Xylazine
4
Silicone Elastomers for Dexamethasone Delivery
To prepare silicone elastomers, the MED-4735 kit from NuSil Technology was used (Carpinteria, CA, USA). The following drugs were studied: dexamethasone (three batches with similar particle sizes in the lower micrometer range, but exhibiting different polymorphic forms: Batch 1: Form A, Batches 2 and 3: blends of Forms A and B) and dexamethasone sodium phosphate (dexamethasone phosphate) (Discovery Fine Chemicals, Dorset, UK). Acetonitrile was used as a solvent (HPLC grade; Fisher Scientific, Illkirch, France). For the preparation of artificial perilymph, the following compounds were used: potassium chloride, sodium chloride, calcium chloride dihydrate, magnesium sulfate tetrahydrate and 4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid (HEPES) (HEPES Pufferan) (Carl Roth, Lauterbourg, France).
Rongthong T., Qnouch A., Maue Gehrke M., Paccou L., Oliveira P., Danede F., Verin J., Vincent C., Willart J.F., Siepmann F, & Siepmann J. (2023). Silicone matrices for controlled dexamethasone release: toward a better understanding of the underlying mass transport mechanisms. Regenerative Biomaterials, 10, rbad008.
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Publication 2023
acetonitrile Calcium Chloride Dihydrate Dexamethasone dexamethasone phosphate dexamethasone sodium phosphate ethane sulfonate HEPES High-Performance Liquid Chromatographies Neutrophil Perilymph Pharmaceutical Preparations Piperazine Potassium Chloride Silicone Elastomers Sodium Chloride Solvents Sulfate, Magnesium
5
Monitoring Deltamethrin Dispersal in Aquatic Ecosystems
The delousing at site 1 took place in the pens
during 3 days in early spring in 2020, and a total of 27 L of Alpha
Max was used, which corresponds to 270 g of deltamethrin for the full
treatment. The site had not been treated with deltamethrin since 2017.35 PAS made of AlteSil silicone rubber sheets
(thickness: 0.5 mm, purchased from Altec, UK) were spiked with performance
reference compounds (PRCs; details in the SI) prior to deployment. These non-naturally occurring compounds are
used to estimate in situ contaminant exchange kinetics
between water and silicone rubber. The samplers (A–E) were
deployed 3 days before delousing, 15–120 m from the deloused
pens at 3–5 m and 10–14 m depth at five sampling sites
(n = 10). PAS were collected 3 days after the delousing
ended (Table S2). Sampler A, situated inside
a deloused pen, was lost, but samplers B–E were recovered and
stored frozen in tin containers until analyses. Surface sediment samples
(n = 10) were collected 5 weeks after the last delousing
event at distances 0–500 m from the pens at 70–130 m
depth with a Van Veen grab, and the 0–1 cm top layer was transferred
to preburned (450 °C) glasses and kept frozen until analyses
(Table S2). Only grabs with an undisturbed
surface were approved for sampling.
Arnberg M., Refseth G.H., Allan I.J., Benedetti M., Regoli F., Tassara L., Sagerup K., Drivdal M., Nøst O.A., Evenset A, & Carlsson P. (2023). Acute and Sublethal Effects of Deltamethrin Discharges from the Aquaculture Industry on Northern Shrimp (Pandalus borealis Krøyer, 1838): Dispersal Modeling and Field Investigations. Environmental Science & Technology, 57(9), 3602-3611.
Full text: Click here
Publication 2023
AT 130 decamethrin Eyeglasses Freezing Silicone Elastomers

Top products related to «Silicone Elastomers»

1
Sylgard 184 silicone elastomer kit by Dow
Sourced in United States, Germany, Belgium, China, United Kingdom
Sylgard 184 Silicone Elastomer Kit is a two-part silicone-based polymer system that can be used to create flexible, durable, and customizable elastomeric components. It consists of a base compound and a curing agent that, when combined, undergo a cross-linking reaction to form the final silicone material.
2
Sylgard 184 by Dow
Sourced in United States, Germany, China, Australia, United Kingdom, Belgium, Japan, Canada, India, France
Sylgard 184 is a two-part silicone elastomer system. It is composed of a siloxane polymer and a curing agent. When mixed, the components crosslink to form a flexible, transparent, and durable silicone rubber. The core function of Sylgard 184 is to provide a versatile material for a wide range of applications, including molding, encapsulation, and coating.
3
Sylgard 184 silicone elastomer by Dow
Sourced in United States, China, Germany
Sylgard 184 Silicone Elastomer is a two-part, platinum-catalyzed silicone encapsulant. It is a versatile material that can be used for a variety of applications, such as potting, molding, and coating. The product is composed of a base and a curing agent that, when mixed, undergo a curing process to form a flexible, durable silicone material.
4
Sylgard 184 silicone elastomer base by Dow
Sourced in United States
Sylgard 184 silicone elastomer base is a two-part, addition-cure silicone elastomer system. It is a viscous, colorless liquid that cures at room temperature to form a flexible, transparent elastomer.
5
Ecoflex 00 30 by Smooth-On
Sourced in United States
Ecoflex 00-30 is a soft, platinum-catalyzed silicone rubber that features a Shore 00-30 hardness. It is a two-part, room temperature vulcanizing (RTV) liquid silicone system.
6
Fetal bovine serum (fbs) by Thermo Fisher Scientific
Sourced in United States, China, United Kingdom, Germany, Australia, Japan, Canada, Italy, France, Switzerland, New Zealand, Brazil, Belgium, India, Spain, Israel, Austria, Poland, Ireland, Sweden, Macao, Netherlands, Denmark, Cameroon, Singapore, Portugal, Argentina, Holy See (Vatican City State), Morocco, Uruguay, Mexico, Thailand, Sao Tome and Principe, Hungary, Panama, Hong Kong, Norway, United Arab Emirates, Czechia, Russian Federation, Chile, Moldova, Republic of, Gabon, Palestine, State of, Saudi Arabia, Senegal
Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
7
Microfil mv 122 by Flow Tech
Sourced in United States
The Microfil MV-122 is a laboratory instrument designed for filtration applications. It is capable of filtering liquids through a variety of membrane types and pore sizes. The device provides precise control over the filtration process, allowing for accurate and reproducible results.
8
Sodium chloride (nacl) by Merck Group
Sourced in United States, Germany, United Kingdom, India, Italy, France, Spain, China, Canada, Sao Tome and Principe, Poland, Belgium, Australia, Switzerland, Macao, Denmark, Ireland, Brazil, Japan, Hungary, Sweden, Netherlands, Czechia, Portugal, Israel, Singapore, Norway, Cameroon, Malaysia, Greece, Austria, Chile, Indonesia
NaCl is a chemical compound commonly known as sodium chloride. It is a white, crystalline solid that is widely used in various industries, including pharmaceutical and laboratory settings. NaCl's core function is to serve as a basic, inorganic salt that can be used for a variety of applications in the lab environment.
9
Su 8 photoresist by MicroChem
Sourced in United States, Japan, Morocco
SU-8 is a negative, epoxy-based photoresist designed for microfabrication applications. It is a high-contrast, chemically amplified resist that is sensitive to near-UV and UV light. SU-8 is commonly used for the creation of high-aspect-ratio microstructures and has a wide range of applications in fields such as microelectronics, microfluidics, and MEMS.
10
Bovine serum albumin (bsa) by Merck Group
Sourced in United States, Germany, United Kingdom, China, Italy, Japan, France, Sao Tome and Principe, Canada, Macao, Spain, Switzerland, Australia, India, Israel, Belgium, Poland, Sweden, Denmark, Ireland, Hungary, Netherlands, Czechia, Brazil, Austria, Singapore, Portugal, Panama, Chile, Senegal, Morocco, Slovenia, New Zealand, Finland, Thailand, Uruguay, Argentina, Saudi Arabia, Romania, Greece, Mexico
Bovine serum albumin (BSA) is a common laboratory reagent derived from bovine blood plasma. It is a protein that serves as a stabilizer and blocking agent in various biochemical and immunological applications. BSA is widely used to maintain the activity and solubility of enzymes, proteins, and other biomolecules in experimental settings.

More about "Silicone Elastomers"

Silicone elastomers are a class of synthetic polymers known for their exceptional physical properties, including flexibility, durability, and resistance to heat and chemicals.
These materials are widely used in various industries, such as medical devices, automotive components, and consumer products.
The Sylgard 184 Silicone Elastomer Kit is a popular example, containing a two-part silicone elastomer that can be easily molded and cured.
Silicone elastomers are composed of silicon, oxygen, and organic groups, which give them their unique characteristics.
They are often used in applications that require a combination of mechanical, thermal, and chemical stability, such as gaskets, seals, and insulations.
The Ecoflex 00-30 is another type of silicone elastomer that is known for its softness and stretchability, making it suitable for applications like soft robotics and wearable electronics.
Beyond their industrial uses, silicone elastomers have also found applications in biomedical research.
For example, Microfil MV-122 is a silicone-based material used to create microfluidic devices, while SU-8 photoresist is a silicone-based polymer used in the fabrication of microelectromechanical systems (MEMS).
Additionally, silicone elastomers can be used in cell culture applications, where they are often combined with materials like bovine serum albumin (BSA) to create a suitable microenvironment for cell growth and differentiation.
The PubCompare.ai platform leverages AI-driven technology to optimize research protocols and enhance reproducibility for silicone elastomers.
This cutting-edge tool helps researchers easily locate protocols from literature, pre-prints, and patents, and use AI-driven comparisons to identify the best protocols and products.
By improving research efficiency and reliability, PubCompare.ai enables scientists to make more informed decisions and accelerate the development of innovative silicone elastomer-based solutions.