A virtual reality system was designed using an air-supported spherical treadmill for head-restrained mice19 (link) in combination with a projection-based visual display system20 (link), in which a toroidal screen presented an image from a projector via an angular amplification mirror21 (link). Custom software to control the virtual reality system was developed based on the Quake2 game engine. Rotations of the spherical treadmill, measured by an optical computer mouse, were used to update the visual display. Water-scheduled C57BL/6J mice (8–12 weeks old) were trained using operant conditioning to run from end-to-end of a virtual linear track (180 cm long) to obtain water rewards. For electrophysiology measurements, a small craniotomy (~0.5 mm diameter) was made centered over dorsal hippocampus (2.2 mm caudal, 1.7 lateral to bregma). The craniotomy was sealed with silicone grease and then covered with silicone elastomer to allow recordings across multiple days. Extracellular recordings were made using a glass electrode (filled with 0.5 M NaCl, ~2.5 MΩ pipette resistance) mounted on a micromanipulator positioned behind the mouse. Whole cell recordings were obtained using standard blind patch methods. Patch pipettes were pulled with a long taper (~100 μm diameter at 1 mm from the tip), to minimize damage to the overlying cortical tissue, and were mounted on a micromanipulator positioned outside the field of view. Firing rate maps were calculated for 80 spatial bins along the virtual track as the number of spikes in a bin divided by the time spent in that bin. Changes in baseline membrane potential in the place field were measured from membrane potential traces excluding spikes. Theta oscillations were analyzed following band-pass filtering (6–10 Hz) of the membrane potential recording using a linear phase finite impulse response filter.
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Silicones
Silicones
Silicones are a class of synthetic polymers composed of silicon, oxygen, and organic moieties.
These versatile materials have a wide range of applications, including use in personal care products, medical devices, and industrial coatings.
Silicones demonstrate unique properties such as thermal stability, water repellency, and low surface tension.
The diverse chemistries and structures of silicones allow for tailoring their characteristics to meet specific requirements.
Reserach in this field focuses on developing novel silicone-based materials and optimizing their performance for various end uses.
Discover how PubCompare.ai's AI-powered platform can enhance your slicones research by easily locating protocols from the literature and leveraging AI-driven comparisons to identify the most accurate and reproducible approaches.
These versatile materials have a wide range of applications, including use in personal care products, medical devices, and industrial coatings.
Silicones demonstrate unique properties such as thermal stability, water repellency, and low surface tension.
The diverse chemistries and structures of silicones allow for tailoring their characteristics to meet specific requirements.
Reserach in this field focuses on developing novel silicone-based materials and optimizing their performance for various end uses.
Discover how PubCompare.ai's AI-powered platform can enhance your slicones research by easily locating protocols from the literature and leveraging AI-driven comparisons to identify the most accurate and reproducible approaches.
Most cited protocols related to «Silicones»
Cortex, Cerebral
Craniotomy
Head
Membrane Potentials
Mice, Inbred C57BL
Microtubule-Associated Proteins
Mus
Seahorses
Silicone Elastomers
Silicones
Sodium Chloride
Strains
Tissues
Visually Impaired Persons
Buffers
Electron Microscopy
Microscopy
RBBP8 protein, human
Silicones
Submersion
Tissues
Optical fiber bundles were purchased from Schott North America (Southbridge, MA). Non-reinforced gloss silicone sheeting was obtained from Specialty Manufacturing (Saginaw, MI). Hydrochloric acid, anhydrous ethanol, and molecular biology grade Tween-20 were all from Sigma-Aldrich (Saint Louis, MO). 2.7-μm-diam. carboxyl-terminated magnetic beads were purchased from Varian, Inc. (Lake Forest, CA). Monoclonal anti-human TNF-α capture antibody, polyclonal anti-human TNF-α detection antibody, and recombinant human TNF-α were purchased from R&D Systems (Minneapolis, MN). Monoclonal anti-PSA capture antibody, monoclonal anti-PSA detection antibody, and purified PSA were purchased from BiosPacific (Emeryville, CA); the detection antibody was biotinylated using standard methods. 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC), N-hydroxysulfosuccinimide (NHS), and SuperBlock® T-20 Blocking Buffer were purchased from Thermo Scientific (Rockford, IL). Purified DNA was purchased from Integrated DNA Technologies (Coralville, IA). Streptavidin-β-galactosidase (SβG) was conjugated in house using standard protocols. Resorufin-β-D-galactopyranoside (RGP) was purchased from Invitrogen (Carlsbad, CA). The fiber polisher and polishing consumables were purchased from Allied High Tech Products (Rancho Dominguez, CA).
Absolute Alcohol
Antibodies, Anti-Idiotypic
Buffers
Carbodiimides
Etanercept
Fibrosis
Forests
GLB1 protein, human
Homo sapiens
Hydrochloric acid
Immunoglobulins
Monoclonal Antibodies
N-hydroxysulfosuccinimide
resorufin galactopyranoside
Silicones
Streptavidin
TNF protein, human
Tween 20
To determine if silicone wristbands
could sequester a wide range of organic compounds, a public query
was made to collect volunteers. Participants were instructed to wear
a wristband continuously for 30 days including bathing, sleeping,
or other activities. A total of 30 precleaned and dried wristbands
were placed inside three amber jars, and metal tongs were used by
participants as they took one or two wristbands to wear. A sign-out
sheet was used to track the number of wristbands a participant took
(1 or 2), but no surnames or personal information was asked or collected
during this initial demonstration. At the end of the 30 day period,
small (250 mL) amber jars were used to collect each individual wristband
and were stored at −20 °C until postdeployment cleaning
and extraction. In addition, three nondeployed wristbands were placed
inside amber jars at room temperature to serve as controls for potential
laboratory or processing contamination.
could sequester a wide range of organic compounds, a public query
was made to collect volunteers. Participants were instructed to wear
a wristband continuously for 30 days including bathing, sleeping,
or other activities. A total of 30 precleaned and dried wristbands
were placed inside three amber jars, and metal tongs were used by
participants as they took one or two wristbands to wear. A sign-out
sheet was used to track the number of wristbands a participant took
(1 or 2), but no surnames or personal information was asked or collected
during this initial demonstration. At the end of the 30 day period,
small (250 mL) amber jars were used to collect each individual wristband
and were stored at −20 °C until postdeployment cleaning
and extraction. In addition, three nondeployed wristbands were placed
inside amber jars at room temperature to serve as controls for potential
laboratory or processing contamination.
Amber
Metals
Organic Chemicals
Silicones
Voluntary Workers
All experimental and surgical procedures were performed in accordance with the experimental protocols (No. H24-2-203(4)) approved by the RIKEN ethics committee and the recommendations of the Weatherall report, "The use of non-human primates in research". Implantation surgery was performed under sodium pentobarbital anesthesia, and all efforts were made to minimize suffering. No animal was sacrificed in this study. Overall care was managed by the Division of Research Resource Center at RIKEN Brain Science Institute. The animal was housed in a large individual enclosure with other animals visible in the room, and maintained on a 12:12-h light:dark cycle. The animal was given food (PS-A; Oriental Yeast Co., Ltd., Tokyo, Japan) and water ad libitum, and also daily fruit/dry treats as a means of enrichment and novelty. The animal was occasionally provided toys in the cage. The in-house veterinary doctor checked the animal and updated daily feedings in order to maintain weight. We have attempted to offer as humane treatment of our subject as possible.
Neural and behavioral recordings were performed by employing a multi-dimensional recording technique [13 (link)]. Chronically implanted, customized multichannel ECoG electrode arrays (Unique Medical, Japan) were used for neural recording [13 (link)]. Electrodes were made of 3-mm diameter platinum discs that were dimpled at the center after being exposed to an insulating silicone sheet 0.8 mm in diameter. The array was implanted in the subdural space in 4 adult macaque monkeys（M1-M3 are Macaca fuscata and M4 is Macaca mulatta). One hundred and twenty-eight channel ECoG electrodes with an interelectrode distance of 5 mm were implanted in the left hemisphere, continuously covering over the frontal, parietal, temporal, and occipital lobes (Figure 1A and S1 ). Additionally the electrodes of Monkey M1 covered the medial frontal and parietal walls and the electrodes of Monkey M2 covered the medial frontal and occipital walls. Reference electrodes were made of rectangular platinum plates placed in the subdural space between the ECoG array and dura mater. Lastly, ground electrodes were placed in the epidural space (See 13 (link) for the detailed method). Parts of the dataset are shared in the public server Neurotycho.org (http://neurotycho.org/
Neural and behavioral recordings were performed by employing a multi-dimensional recording technique [13 (link)]. Chronically implanted, customized multichannel ECoG electrode arrays (Unique Medical, Japan) were used for neural recording [13 (link)]. Electrodes were made of 3-mm diameter platinum discs that were dimpled at the center after being exposed to an insulating silicone sheet 0.8 mm in diameter. The array was implanted in the subdural space in 4 adult macaque monkeys（M1-M3 are Macaca fuscata and M4 is Macaca mulatta). One hundred and twenty-eight channel ECoG electrodes with an interelectrode distance of 5 mm were implanted in the left hemisphere, continuously covering over the frontal, parietal, temporal, and occipital lobes (
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Adult
Anesthesia
Animals
Asian Persons
Brain
Dura Mater
Electrocorticography
Ethics Committees
Food
Fruit
Homo sapiens
Japanese Monkeys
Macaca
Macaca mulatta
Monkeys
Nervousness
Occipital Lobe
Operative Surgical Procedures
Ovum Implantation
Pentobarbital Sodium
Physicians
Platinum
Primates
Silicones
Spaces, Epidural
Subdural Space
Yeast, Dried
Most recents protocols related to «Silicones»
Example 3
Moulded Silicone Pressure Sensitive Adhesive Body:
Dow Corning 7-9800 A&B (mixing ration between A and Bis 1:1 by weight) were used for production of a PDMS based adhesive body. A mould having a triangular shape (each side of the triangular mould having a distance of 300 mm, the center part having a thickness of 0.5 mm and the edge having a thickness of 0.1 mm) was used. The components were thoroughly mixed and applied on a 50 μm cover layer of silicone rubber lining in the female part of a triangular mould and a male mould part was placed on top, said part lined with a low density polyethylene release liner. The adhesive was cured in an oven at 100 degree C. for 15 minutes. After curing the adhesive was punched out of the mould and a dent in the centre of the adhesive body device for embedment of an electronic sensing system was punched out.
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A 300
Dental Cavity Liner
Females
Fungus, Filamentous
Human Body
Males
Polyethylene, Low-Density
Pressure
Silicone Elastomers
Silicones
Example 6
ICP is monitored using a Samba 420 Sensor, pressure transducer, with a Samba 202 control unit (Harvard Apparatus, Holliston, MA). This ICP monitoring system consists of a 0.42 mm silicon sensor element mounted on an optical fiber. A 20-gauge syringe needle is implanted through the cisterna magna to a depth of ˜1 cm. The needle then acts as a guide for insertion of the Samba Sensor and the site of implantation and the open end of the needle are sealed with 100% silicone sealant. A baseline ICP reading is established followed by a water bolus IP injection (20% weight of animal) with or without Compound 1. ICP is monitored until the animal expires from the water load.
Adjusting for the slight rise in ICP observed in the animals when they are monitored without the water bolus injection (
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Acceptance and Commitment Therapy
Animals
Injections, Intraperitoneal
Intracranial Pressure
Magna, Cisterna
Mice, Laboratory
Needles
Ovum Implantation
Silicon
Silicones
Syringes
Transducers, Pressure
Example 3
A primer composition is prepared using Citronellol polymer, according to the following table (percent values shown are w/w):
The primer composition is prepared heating the propylene glycol to 70-75° C. in a beaker, then slowly adding the silica dimethyl silylate with stirring to form a uniform gel. The Citronellol polymer is then added with stirring, followed by cooling the mixture. The preservative is then added after the mixture has cooled below 40° C. The resulting product is uniform gel with a velvet-like feel after application to the skin. Compared to a similar commercial silicone-based primer, the present primer provides a smoother and more glowy appearance on the skin.
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citronellol
Emollients
Feelings
Oligonucleotide Primers
Pharmaceutical Preservatives
phenoxyethanol
Polymers
Propylene Glycol
Silicon Dioxide
Silicones
Skin
Example 1
30 parts of (A) an amino-modified silicone (Si-1), 5 parts of (B) the nonionic surfactant (N-4), and 65 parts of ion-exchanged water were stirred well, and then emulsified using a homogenizer, to prepare an aqueous liquid of a carbon fiber precursor treatment agent having a solid concentration of 35% in Example 1.
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Carbon Fiber
Silicones
Surface-Active Agents
Example 1
The respective ingredients shown in Table 1 were used and added to a beaker such that blending ratios are 29.97% of a sulfur-containing ester compound (A-1a), 0.03% of a sulfur-containing ester compound (A-1b), 45% of a modified silicone (C-1), and 25% of a surfactant (L-1). These were mixed well by stirring. While continuing to stir, ion exchanged water was added gradually to achieve a solids concentration of 25% and thereby prepare a 25% aqueous liquid of a carbon fiber precursor treatment agent of Example 1.
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A-A-1 antibiotic
Carbon Fiber
Silicones
Sulfuric Acid Esters
Surface-Active Agents
Top products related to «Silicones»
Sourced in United States, Germany, China, Australia, United Kingdom, Belgium, Japan, Canada, India, France
Sylgard 184 is a two-part silicone elastomer system. It is composed of a siloxane polymer and a curing agent. When mixed, the components crosslink to form a flexible, transparent, and durable silicone rubber. The core function of Sylgard 184 is to provide a versatile material for a wide range of applications, including molding, encapsulation, and coating.
Sourced in United States, Sao Tome and Principe, Japan, Germany, Canada, Sweden, Italy, United Kingdom
Tegaderm is a transparent wound dressing made by 3M. It is a sterile, semi-permeable film that allows for the passage of water vapor and oxygen while preventing the entry of microorganisms. Tegaderm serves as a protective barrier for wounds and incisions.
Sourced in United States, China, United Kingdom, Germany, Australia, Japan, Canada, Italy, France, Switzerland, New Zealand, Brazil, Belgium, India, Spain, Israel, Austria, Poland, Ireland, Sweden, Macao, Netherlands, Denmark, Cameroon, Singapore, Portugal, Argentina, Holy See (Vatican City State), Morocco, Uruguay, Mexico, Thailand, Sao Tome and Principe, Hungary, Panama, Hong Kong, Norway, United Arab Emirates, Czechia, Russian Federation, Chile, Moldova, Republic of, Gabon, Palestine, State of, Saudi Arabia, Senegal
Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
Sourced in United States
Ecoflex 00-30 is a soft, platinum-catalyzed silicone rubber that features a Shore 00-30 hardness. It is a two-part, room temperature vulcanizing (RTV) liquid silicone system.
DC 255 silicone resin is a liquid, heat-curable material formulated for use as a binder, coating, or sealant. It is designed to provide thermal and electrical insulation properties. The resin has a clear, colorless appearance.
Sourced in Germany
Silicone culture inserts are a type of lab equipment used for cell culture applications. They provide a platform for cells to grow and proliferate in a controlled environment. The inserts are made of silicone material and offer a stable and uniform surface for cell attachment and growth.
Sourced in United States, Germany, United Kingdom, China, Canada, France, Japan, Australia, Switzerland, Israel, Italy, Belgium, Austria, Spain, Gabon, Ireland, New Zealand, Sweden, Netherlands, Denmark, Brazil, Macao, India, Singapore, Poland, Argentina, Cameroon, Uruguay, Morocco, Panama, Colombia, Holy See (Vatican City State), Hungary, Norway, Portugal, Mexico, Thailand, Palestine, State of, Finland, Moldova, Republic of, Jamaica, Czechia
Penicillin/streptomycin is a commonly used antibiotic solution for cell culture applications. It contains a combination of penicillin and streptomycin, which are broad-spectrum antibiotics that inhibit the growth of both Gram-positive and Gram-negative bacteria.
Sourced in Germany
Silicone inserts are a type of laboratory equipment designed to provide a reliable and consistent seal for various applications. They are made of high-quality silicone material and offer a durable and flexible solution for sealing vessels, tubes, and other laboratory equipment.
Sourced in United States
The MiniMuffs are a compact and portable noise-reduction system designed for use in medical and laboratory settings. The product's core function is to provide a controlled acoustic environment to protect sensitive hearing during procedures or examinations.
Sourced in Germany
The 2-well silicone inserts are a laboratory equipment designed to create two separate culture areas within a single well. They are made of silicone material and can be used in a variety of cell culture applications.
More about "Silicones"
Silicones are a diverse class of synthetic polymers composed of silicon, oxygen, and various organic moieties.
These versatile materials, also known as polysiloxanes, have a wide range of applications in personal care products, medical devices, industrial coatings, and beyond.
Key characteristics of silicones include thermal stability, water repellency, and low surface tension.
Researchers in this field focus on developing novel silicone-based materials and optimizing their performance for specific end uses.
Silicones can be tailored through diverse chemistries and structures to meet a variety of requirements.
For example, Sylgard 184 is a popular two-part silicone elastomer used for microfluidic devices and cell culture applications, while Tegaderm is a silicone-based wound dressing.
Silicone culture inserts and 2-well silicone inserts are utilized in cell culture research, often in conjunction with fetal bovine serum (FBS) and penicillin/streptomycin antibiotics.
Ecoflex 00-30 is a soft, platinum-catalyzed silicone rubber, and DC 255 silicone resin offers unique properties for industrial coatings and sealants.
Advances in silicone research, enabled by tools like PubCompare.ai's AI-powered platform, allow scientists to easily locate relevant protocols from the literature, pre-prints, and patents, and leverage AI-driven comparisons to identify the most accurate and reproducible approaches.
This can help improve research outcomes and accelerate innovation in the diverse and ever-evolving field of silicones.
These versatile materials, also known as polysiloxanes, have a wide range of applications in personal care products, medical devices, industrial coatings, and beyond.
Key characteristics of silicones include thermal stability, water repellency, and low surface tension.
Researchers in this field focus on developing novel silicone-based materials and optimizing their performance for specific end uses.
Silicones can be tailored through diverse chemistries and structures to meet a variety of requirements.
For example, Sylgard 184 is a popular two-part silicone elastomer used for microfluidic devices and cell culture applications, while Tegaderm is a silicone-based wound dressing.
Silicone culture inserts and 2-well silicone inserts are utilized in cell culture research, often in conjunction with fetal bovine serum (FBS) and penicillin/streptomycin antibiotics.
Ecoflex 00-30 is a soft, platinum-catalyzed silicone rubber, and DC 255 silicone resin offers unique properties for industrial coatings and sealants.
Advances in silicone research, enabled by tools like PubCompare.ai's AI-powered platform, allow scientists to easily locate relevant protocols from the literature, pre-prints, and patents, and leverage AI-driven comparisons to identify the most accurate and reproducible approaches.
This can help improve research outcomes and accelerate innovation in the diverse and ever-evolving field of silicones.