> Chemicals & Drugs > Chemical Viewed Structurally > Borohydrides

← Borates

Cations →

Borohydrides

Q: What are Borohydrides and what makes them useful?

Borohydrides are a class of chemical compounds that contain the borohydride ion (BH4-), which is a powerful reducing agent. These compounds exhibit unique properties and versatile reactivity, making them valuable tools for researchers in fields like organic chemistry, medicinal chemistry, and materials science. Borohydrides are extensively used in organic synthesis and other applications due to their ability to selectively reduce a wide range of functional groups.

Q: What are some common types or variations of Borohydrides?

The most common types of Borohydrides include Sodium Borohydride (NaBH4), Lithium Borohydride (LiBH4), and Potassium Borohydride (KBH4). These compounds differ in their solubility, reactivity, and selectivity, allowing researchers to choose the most appropriate Borohydride for their specific application.

Q: What are some of the challenges in using Borohydrides?

One of the main challanges in using Borohydrides is their sensitivity to moisture and acidic conditions, which can lead to the decomposition of the compounds and the release of hydrogen gas. Researchers must take precautions to handle Borohydrides in a dry, inert atmosphere to ensure optimal performance and safety.

Q: How can PubCompare.ai help with Borohydride research?

PubCompare.ai allows researchers to screen protocol literature more efficiently and leverage AI to pinpoint critical insights. The platform's AI-driven analysis can help researchers identify the most effective protocols related to Borohydrides for their specific research goals, highlighting key differences in protocol effectiveness and enabling them to choose the best option for reproducibility and accuarcy.

Borohydrides are a class of chemical compounds containing the borohydride ion (BH4-), which is a powerful reducing agent used extensively in organic synthesis and other applications.
These compounds exhibit unique properties and versatile reactivity, making them valuable tools for researchers in fields like organic chemistry, medicinal chemistry, and materials science.
PubCompare.ai can help optimize your borohydride research by locating the best protocols from literature, preprints, and patents using AI-driven comparisons to enhance reproducibility and accuracy.
Identify the most effective borohydride products and procedures with PubCompare.ai's powerul toos.

Most cited protocols related to «Borohydrides»

Synthesis of Lignin Model Compounds

Model compounds were prepared and their NMR spectra were acquired in DMSO to enable the assignments made in a previous paper.² Coniferyl alcohol and sinapyl alcohol were prepared from commercially available coniferaldehyde and sinapaldehyde using borohydride exchange resin.^{105 (link)}p-Coumaryl alcohol was synthesized from p-coumaric acid.¹⁰⁶ Coniferyl alcohol dimers were synthesized from in vitro radical coupling reactions using MnO₂ in dioxane :H₂O (1 : 1, v/v).¹⁰⁷ Sinapyl alcohol dimers were prepared using FeCl₃·6H₂O in dioxane :H₂O (5 : 2, v/v).¹⁰⁸p-Coumaryl alcohol dimers were synthesized with horseradish peroxidase with hydrogen peroxide in acetone :water (1 : 10, v/v) or with FeCl₃·6H₂O in acetone: H₂O (5 : 1, v/v). Each metallic oxidative radical reaction was stirred for 1 to 4 h, and the metal salts were filtered off through a silica gel bed in fine sintered glass filters. The peroxidase reactions were conducted for about 15 h. Reaction solutions were poured into EtOAc, and washed with satd. aqueous NH₄Cl. EtOAc extracts were dried over anhydrous MgSO₄, and concentrated under reduced pressure. Model dimers were separated on preparative TLC plates with CHCl₃–MeOH (10 : 1, v/v). The fully authenticated NMR data for model compounds will be deposited in the “NMR Database of lignin and cell wall model compounds” available via the internet.⁴⁸

Kim H, & Ralph J. (2009). Solution-state 2D NMR of ball-milled plant cell wall gels in DMSO-d6/pyridine-d5. Organic & biomolecular chemistry, 8(3), 576-591.

Publication 2009

Acetone Borohydrides Cell Wall Chloroform coniferaldehyde coniferyl alcohol Coumaric Acids dioxane Ethanol Horseradish Peroxidase Lignin Metals p-coumaryl alcohol Peroxidase Peroxide, Hydrogen Pressure Resins, Plant Salts Silica Gel sinapaldehyde sinapyl alcohol Sulfate, Magnesium Sulfoxide, Dimethyl

Tissue Microarray Immunohistochemistry Protocol

The tissue microarray block was sliced into 5-μm sections that were affixed to slides and dried. Slides were dewaxed four times in xylene, twice in isopropanol, and rehydrated using graded ethanol. The slides were washed and permabilized using Phosphate Buffered Saline (PBS, Fisher Scientific, Waltham, MA) containing 0.1% Triton X-100. Epitope retrieval was performed by heating the slides in Na-citrate buffer (100 mM, pH 6.0) at < 100°C in a domestic vegetable steamer for 30 minutes, followed by cooling slowly to bench temperature. After washing in PBS, endogenous peroxidase activity was eliminated using mild conditions: 1.8% H₂O₂ for 5 minutes, 1% Periodate for 5 minutes, 0.02% NaBH₄ for 2 minutes [71]. The slides were blocked using Serum-Free Protein Block (Dako North America, Inc., Carpinteria, CA, USA) and incubated with primary antibodies overnight at room temperature, at 1:100 dilution. After washing in PBS, the HiDefTM HRP-polymer system (Cell Marque, Rocklin, CA, USA) was used to functionalize with peroxidase, and visualization was performed using the Dako DAB chromogen kit according to manufacturer's guidelines. Slides used for quantification were treated with DAPI and visualized using fluorescence microscopy to identify non-necrotic areas of the tumors. Additional slides were also incubated with hematoxylin/100 mM LiOH to render the nuclei blue for visualization of cells using transmission microscopy.
Glioma cells and NHA were fixed in ice-cold 4% PFA and were washed/permeabilized with 0.1% Triton X-100 in PBS and treated with Dako protein blocking solution. Levels of ketones/aldehyde were measured using ARP/borohydride (Invitrogen/Molecular Probes, Eugene, OR, USA) and visualized using fluorescein isothiocyanate conjugated with egg white avidin (FITC-avidin) as previously described [72].

Sharpe M.A, & Baskin D.S. (2015). Monoamine oxidase B levels are highly expressed in human gliomas and are correlated with the expression of HiF-1α and with transcription factors Sp1 and Sp3. Oncotarget, 7(3), 3379-3393.

Full text: Click here

Publication 2015

Aldehydes Antibodies azo rubin S Borohydrides Buffers Cells Citrates Cold Temperature DAPI Egg White Epitopes Ethanol fluorescein isothiocyante avidin Glioma Hematoxylin Isopropyl Alcohol Ketones Locus Coeruleus metaperiodate Microarray Analysis Microscopy Microscopy, Fluorescence Molecular Probes Necrosis Neoplasms Peroxidase Peroxide, Hydrogen Phosphates Polymers Proteins Saline Solution Serum Proteins Technique, Dilution Tissues Transmission, Communicable Disease Triton X-100 Vegetables Xylene

Isolation and Analysis of T. forsythia S-layer O-glycans

S-layer O-glycans were isolated from T. forsythia mutant cells following a published protocol (Posch et al., 2011 (link)). Briefly, S-layer glycoproteins were excised from Coomassie Brilliant Blue R-250-stained SDS-PA gels and O-glycans were released from the protein backbone by in-gel reductive β-elimination followed by removal of excess of salt using a 25-mg HyperSep Hypercarb SPE cartridge (Thermo Scientific). Borohydride-reduced O-glycans were analyzed by PGC-ESI-MS/MS as described recently (Hypercarb, 0.32 × 150 mm, particle size 5 μm) (Stadlmann et al., 2008 (link)). Detection was done by an ESI-Q-TOF Global Ultima from Micromass (Waters, USA). Data were evaluated using MassLynx 4.0 software. MS/MS experiments were performed at 30% collision energy using CID with argon gas. Slices from the SDS-polyacrylamide gel without sample application were treated in the same way as described for the O-glycan samples and acquired MS spectra were used as a negative control.

Tomek M.B., Neumann L., Nimeth I., Koerdt A., Andesner P., Messner P., Mach L., Potempa J.S, & Schäffer C. (2014). The S-layer proteins of Tannerella forsythia are secreted via a type IX secretion system that is decoupled from protein O-glycosylation. Molecular oral microbiology, 29(6), 307-320.

Publication 2014

Argon Borohydrides Cells Coomassie brilliant blue R Forsythia polyacrylamide gels Polysaccharides Proteins S-layer glycoproteins Sodium Chloride Tandem Mass Spectrometry Vertebral Column

Fabrication of Fe/Pd Nanoparticle-Embedded PVDF-PAA Membranes

Fe/Pd NPs were synthesized via ion exchange, borohydride reduction and palladium post coating procedure reported in our previous studies.^{22 , 28} PVDF-PAA membranes were soaked in NaCl (68.4 mM) solution for cation exchange. The ionized carboxyl groups chelated with Na⁺ while releasing H⁺. Therefore, NaOH was added to maintain the pH. After 12 h, the membranes were washed by deoxygenated water to remove the excess NaCl/NaOH inside the pores. They were then immersed in FeCl₂ solution (3.57 mM, pH=5.0–5.3) for a second ion exchange with N₂ protection (4 h). Na⁺ was replaced by Fe²⁺, forming the iron-carboxylate bonds. Fe²⁺ was immediately reduced to zero-valent iron NPs when soaking the membranes in NaBH₄ solution (26.4 mM). The post coating of Pd NPs on iron surface was achieved by soaking the PVDF-PAA-Fe membranes in K₂PdCl₄ solution (153 µM, ethanol:water=9:1 v/v) for 2 h. Pd²⁺ were reduced by Fe⁰, forming Pd⁰ and Fe²⁺. The membranes were washed with the deoxygenated water before use.

Gui M., Ormsbee L.E, & Bhattacharyya D. (2013). Reactive Functionalized Membranes for Polychlorinated Biphenyl Degradation. Industrial & engineering chemistry research, 52(31), 10430-10440.

Publication 2013

Borohydrides Ethanol Ion Exchange Iron Palladium polyvinylidene fluoride potassium palladium chloride Sodium Chloride Tissue, Membrane

CTC Isolation, Immunostaining, and PD-L1 Detection

Plasma was isolated from samples by centrifugation for 20 minutes at 300 ×g before CTC enrichment with anti-EpCAM coated magnetic beads (Appendix 1). The CTC capture process was carried out using anti-EpCAM beads in a modified protocol developed in our laboratory (31 (link)). Captured cells were immunostained with antibody cocktail containing three mixed pan-cytokeratin antibodies to ensure broad cytokeratin coverage, CD45, CD16, and CD66b antibodies to exclude hematopoietic cells and anti-PD-L1 antibody (28.8) to detect PD-L1 expression as detailed in Appendix 1.
In parallel, another blood sample was processed using the Parsortix system at 99-mbar through a 6.5-µm cassette (Figure 1). Enriched cells were harvested according to the manufacturer’s instructions and fixed for 10 minutes at room temperature with 4% paraformaldehyde (PFA). A total of 8–9 mL of blood was processed through each method. To increase the numbers of markers to be interrogated, such as EpCAM expression separate from cytokeratins, vimentin, and PD-L1 expression (29 (link)), we adapted the quenching and re-staining protocol described by Adams et al. (32 (link)). This protocol utilises borohydride to quench fluorescent signals after an initial round of immunostaining followed by a second round of staining for additional markers, allowing for multi-phenotype analysis of CTCs. The PD-L1 detection, quenching, and restaining methods were standardised using MCF7, MCF7 induced with IFN-γ, MDA-MB-231 cell lines spiked into white blood cells (WBCs) from healthy control donors as detailed in Appendix 1.

Acheampong E., Abed A., Morici M., Spencer I., Beasley A.B., Bowyer S., Asante D.B., Lomma C., Lin W., Millward M, & Gray E.S. (2022). Evaluation of PD-L1 expression on circulating tumour cells in small-cell lung cancer. Translational Lung Cancer Research, 11(3), 440-451.

Publication 2022

Antibodies Antibodies, Anti-Idiotypic BLOOD Borohydrides CD274 protein, human CEACAM8 protein, human Cells Centrifugation Combined Antibody Therapeutics Cytokeratin Donors Hematopoietic System Interferon Type II Leukocytes MCF-7 Cells MDA-MB-231 Cells paraform Phenotype Plasma TACSTD1 protein, human Vimentin

Most recents protocols related to «Borohydrides»

Measuring Cytosolic and Mitochondrial Ca2+ in Isolated RV Myocytes

Isolated RV myocytes from each heart were divided into aliquots for the different measurements carried out. For cytosolic Ca²⁺, cells were loaded with 10 µM Fura-2/AM (Invitrogen, Thermo Fisher Scientific, Waltham, MA, USA) dissolved in 20 µL dimethyl sulphoxide anhydrous (DMSO, ThermoFisher) with 20% pluronic Invitrogen (Scientific, Life Technologies NZ, Auckland, New Zealand) for 20 min at room temperature. Cells were then washed with 1 mM Ca²⁺ Tyrode’s solution for at least 10 min prior to imaging. Mitochondrial Ca²⁺ measurements were taken in cells loaded with di-hydroRhod-2 (dhRhod-2), as previously described [17 (link)]. Briefly, a single 50 µg vial of Rhod-2 indicator (Invitrogen, Scientific, Life Technologies NZ) was dissolved in DMSO and 20% pluronic in DMSO was added. The smallest possible amount of Na⁺ borohydride (reducing agent) was dissolved in 20 µL methanol, and 10 µL was added to the Rhod-2 vial. After 5–10 min, 1 mL of cell suspension was added to 5 µM dhRhod-2 and left for 1 h at 37 °C. Cells were then washed for at least 30 min prior to imaging.

Krstic A.M., Power A.S, & Ward M.L. (2023). Increased Mitochondrial Calcium Fluxes in Hypertrophic Right Ventricular Cardiomyocytes from a Rat Model of Pulmonary Artery Hypertension. Life, 13(2), 540.

Full text: Click here

Publication 2023

Borohydrides Cells Cytosol fura-2-am Methanol Mitochondrial Inheritance Myocytes, Cardiac Pluronics Reducing Agents rhod-2 Sulfoxide, Dimethyl

Synthesis of Functionalized Hydroxy-Terminated Polybutadiene

An amount of 5.0 g BR-900 rubber was dissolved in 100 mL THF, and 3-chloroperoxybenzoic tetrahydrofuran solution was added dropwise to carry out epoxidation for 1.5 h at 30 °C. Then, periodic acid–tetrahydrofuran was added for an oxidative cracking reaction for 2 h. Then, certain amounts of sodium bicarbonate and 2,6-ditertbutyl-4-methylphenol antioxidant were added, and the mixture was kept overnight. Then, sodium borohydride in 50 mL THF was added and reacted at 30 °C for 2 h. The excess sodium borohydride was quenched by adding deionized water at room temperature. Then, 10 g Na₂CO₃ was added under stirring for 1 h. The mixture solution was spin evaporated to obtain HTPB with a yield of 88.5%. ¹H-NMR (400 MHz, CDCl₃): δ (ppm): 1.94 (s, 2 H), 2.02 (t, 2 H), 3.72 (s, 2 H), 5.38 (t, 2 H); ¹³C-NMR (125 MHz, CDCl₃): δ (ppm): 27.2 (CH₂), 32.5 (CH₂), 62.6 (CH₂OH), 129.4 (CH), 142.3 (CHCH₂).
Before adding Na₂CO₃, 8 mL of concentrated hydrochloric acid was added dropwise to the mixture solution and reacted for 30 min. Then, 10 g Na₂CO₃ and a certain amount of functionalized acetylferrocene, which was prepared by refluxing acetylferrocene and p-phenylenediamine in methanol solution, were added and stirred for 1 h. The mixture solution was evaporated by spinning to obtain m-HTPB with a yield of 82.4%. ¹H-NMR (400 MHz, CDCl₃): δ (ppm): 1.43 (s, 3 H), 1.94 (s, 6 H), 2.02 (m, 2H), 3.72 (t, 2 H), 5.38 (t, 2 H); ¹³C-NMR (125 MHz, CDCl₃): δ (ppm): 20.00 (CH₃), 27.2 (CH₂), 32.5 (CH₂), 62.6 (CH₂OH), 69.67 (Cp), 129.4 (CH), 139.7 (C₆H₄N₂H₄), 142.3 (CHCH₂), 201.7 (CO).

Yuan B., Wang G., Tian W., Zhou L, & Li C. (2023). Fabrication of Hydroxy-Terminated Polybutadiene with Piezoelectric Property by Functionalized Branch Chain Modification. Molecules, 28(4), 1810.

Full text: Click here

Publication 2023

1-acetylferrocene 1H NMR 4-phenylenediamine Antioxidants Bicarbonate, Sodium Borohydrides Carbon-13 Magnetic Resonance Spectroscopy cresol Hydrochloric acid Hypernatremia Methanol Periodic Acid Rubber sodium borohydride tetrahydrofuran

Chestnut Shell-Derived Green Synthesis of Silver Nanoparticles

Chestnut shells were crushed with a pulverizer and the obtained powder was collected after passing through a 45 mesh sieve. A total of 5 g chestnut shell powder was placed into a round-bottom flask, and 100 mL 40% ethanol was added. The flask was then transferred into an ultrasonic microwave reactor. The extraction was maintained for 10 min under the condition of 360 W power, and then the extract was collected. The supernatant (~65 mL) of the extract was collected after centrifugation at 5000 r/min for 10 min. Following this, 20 mL of the supernatant was diluted to 40 mL with ultra-pure water and used for the following synthesis.
In a typical synthesis experiment, 40 mL of the diluted chestnut-shell-extract solution was mixed with 0.4 mL 5% AgNO₃ solution. The solution’s pH was adjusted to 9.0 with the concentrated ammonia. After further stirring, 40 mL of solution was put into a Teflon-lined autoclave (50 mL), then the reactor placed into the oven and maintained at 140 °C for 4 h [14 (link),17 (link)]. The produced solution was collected after the reaction for the following characterization. In this study, different synthesis conditions (pH ranging from 5.0 to 11.0 and ratio of the reactants ranging from 1:4 to 4:1 of the typical experimental conditions) have been investigated.
In order to compare with the results of functionalized chestnut-shell-extract Ag nanoparticles, Ag nanoparticles (AgNPs) were also synthesized by a sodium borohydride (NaBH₄) reduction method [19 (link)], and can be regarded as nonfunctionalized AgNPs. The excess sodium borohydride can efficiently reduce silver nitrate to produce AgNPs. In a typical reaction, 10 mL of silver nitrate (1.0 mM) was gradually dropped into 30 mL of sodium borohydride solution (2.0 mM, chilled in an ice bath) over 3 min under rigorous stirring.

Shao K., Sun J., Lin Y., Zhi H., Wang X., Fu Y., Xu J, & Liu Z. (2023). Green Synthesis and Antimicrobial Study on Functionalized Chestnut-Shell-Extract Ag Nanoparticles. Antibiotics, 12(2), 201.

Full text: Click here

Publication 2023

Ammonia Anabolism Bath Borohydrides Centrifugation Ethanol Hypernatremia Microwaves Muscle Rigidity Powder Silver Nitrate sodium borohydride Teflon Training Programs Ultrasonics

Biosugar to Sorbitol Conversion

Protocol full text hidden due to copyright restrictions

Open the protocol to access the free full text link

Publication 2023

Borohydrides Catalysis Glucose High-Performance Liquid Chromatographies Hydrogenation Hypernatremia sodium borohydride Sorbitol

4-NP to 4-AP Reduction on NPs and NCs

The 4-NP to 4-AP reduction procedures on the surface of NPs and NCs were adapted from a recent study.^{18 (link)} To give a rich yellow color, 1.10 mL of 0.01 M (1.1 × 10⁻⁴ M) 4-NP was mixed with 0.38 g/100 mL (0.1 M) of excess sodium borohydride (NaBH₄). In this case, NaBH₄ was used to reduce 4-NP to the 4-nitrophenolate ion. After adding 10 mg of the catalyst to the mixture, a UV-vis spectrophotometer (P9 UV/Visible double-beam spectrophotometer) was used to track the conversion of 4-NP to 4-AP.

Abebe B., Kefale B, & Leku D.T. (2023). Synthesis of copper–silver–zinc oxide nanocomposites for 4-nitrophenol reduction: doping and heterojunction. RSC Advances, 13(7), 4523-4529.

Publication 2023

Borohydrides Hypernatremia sodium borohydride

Top products related to «Borohydrides»

Nabh4 by Merck Group

Sourced in United States, Germany, India, China, France, United Kingdom, Poland, Canada, Sao Tome and Principe, Ireland, Spain

NaBH4 is a reducing agent commonly used in organic synthesis. It is a white crystalline solid that reacts with various functional groups to facilitate reduction reactions. The core function of NaBH4 is to serve as a source of hydride ions for the selective reduction of carbonyl compounds, such as aldehydes and ketones, to alcohols.

Sodium hydroxide (naoh) by Merck Group

Sourced in Germany, United States, India, United Kingdom, Italy, China, Spain, France, Australia, Canada, Poland, Switzerland, Singapore, Belgium, Sao Tome and Principe, Ireland, Sweden, Brazil, Israel, Mexico, Macao, Chile, Japan, Hungary, Malaysia, Denmark, Portugal, Indonesia, Netherlands, Czechia, Finland, Austria, Romania, Pakistan, Cameroon, Egypt, Greece, Bulgaria, Norway, Colombia, New Zealand, Lithuania

Sodium hydroxide is a chemical compound with the formula NaOH. It is a white, odorless, crystalline solid that is highly soluble in water and is a strong base. It is commonly used in various laboratory applications as a reagent.

Wheat arabinoxylan by Megazyme

Sourced in Ireland

Wheat arabinoxylan is a polysaccharide extracted from the cell walls of wheat. It is a complex heteropolysaccharide composed of a backbone of xylose units with arabinosyl side chains. This product is suitable for use in research applications involving the study of plant cell wall components.

Konjac glucomannan by Megazyme

Sourced in Ireland

Konjac glucomannan is a water-soluble dietary fiber derived from the roots of the konjac plant. It is a neutral polysaccharide composed of glucose and mannose units. Konjac glucomannan is commonly used as a thickening and gelling agent in food and pharmaceutical applications.

Ethanol by Merck Group

Sourced in Germany, United States, United Kingdom, Italy, India, France, China, Australia, Spain, Canada, Switzerland, Japan, Brazil, Poland, Sao Tome and Principe, Singapore, Chile, Malaysia, Belgium, Macao, Mexico, Ireland, Sweden, Indonesia, Pakistan, Romania, Czechia, Denmark, Hungary, Egypt, Israel, Portugal, Taiwan, Province of China, Austria, Thailand

Ethanol is a clear, colorless liquid chemical compound commonly used in laboratory settings. It is a key component in various scientific applications, serving as a solvent, disinfectant, and fuel source. Ethanol has a molecular formula of C2H6O and a range of industrial and research uses.

D 7000 series by Hitachi

Sourced in United States, Japan

The Hitachi D-7000 Series is a line of analytical laboratory equipment. It is designed to perform a variety of analytical tasks within a laboratory setting. The core function of the D-7000 Series is to provide precision measurement and data analysis capabilities for laboratory researchers and technicians.

Glutaraldehyde by Merck Group

Sourced in United States, Germany, United Kingdom, Italy, Switzerland, India, China, Sao Tome and Principe, France, Canada, Japan, Spain, Belgium, Poland, Ireland, Israel, Singapore, Macao, Brazil, Sweden, Czechia, Australia

Glutaraldehyde is a chemical compound used as a fixative and disinfectant in various laboratory applications. It serves as a cross-linking agent, primarily used to preserve biological samples for analysis.

Larch arabinogalactan by Megazyme

Sourced in Ireland

Larch arabinogalactan is a natural, high-molecular-weight polysaccharide derived from the wood of the larch tree. It is a linear polymer composed of galactose and arabinose residues. Larch arabinogalactan is a soluble fiber with a complex molecular structure.

Carob galactomannan by Megazyme

Sourced in Ireland

Carob galactomannan is a polysaccharide extracted from the endosperm of the carob tree (Ceratonia siliqua). It is a water-soluble gum with a high molecular weight and a ratio of galactose to mannose typically between 1:3 and 1:4. Carob galactomannan is commonly used as a thickening, stabilizing, and gelling agent in various food, pharmaceutical, and industrial applications.

Sodium borohydride by Merck Group

Sourced in United States, Germany, Italy, France, Spain, United Kingdom, China, Canada, India, Poland, Sao Tome and Principe, Australia, Mexico, Ireland, Netherlands, Japan, Singapore, Sweden, Pakistan

Sodium borohydride is a reducing agent commonly used in organic synthesis and analytical chemistry. It is a white, crystalline solid that reacts with water to produce hydrogen gas. Sodium borohydride is frequently employed in the reduction of carbonyl compounds, such as aldehydes and ketones, to alcohols. Its primary function is to facilitate chemical transformations in a laboratory setting.

What are Borohydrides and what makes them useful?

Borohydrides are a class of chemical compounds that contain the borohydride ion (BH4-), which is a powerful reducing agent. These compounds exhibit unique properties and versatile reactivity, making them valuable tools for researchers in fields like organic chemistry, medicinal chemistry, and materials science. Borohydrides are extensively used in organic synthesis and other applications due to their ability to selectively reduce a wide range of functional groups.

What are some common types or variations of Borohydrides?

What are some of the challenges in using Borohydrides?

How can PubCompare.ai help with Borohydride research?

PubCompare.ai allows researchers to screen protocol literature more efficiently and leverage AI to pinpoint critical insights. The platform's AI-driven analysis can help researchers identify the most effective protocols related to Borohydrides for their specific research goals, highlighting key differences in protocol effectiveness and enabling them to choose the best option for reproducibility and accuarcy.

More about "Borohydrides"

Borohydrides are a versatile class of chemical compounds that contain the borohydride ion (BH4-), a powerful reducing agent widely used in organic synthesis and various applications.
These compounds exhibit unique properties and diverse reactivity, making them invaluable tools for researchers in fields like organic chemistry, medicinal chemistry, and materials science.
Sodium borohydride (NaBH4) is a commonly used borohydride compound, known for its ability to reduce a variety of functional groups, such as aldehydes, ketones, and esters.
It is often employed in the synthesis of alcohols, ethers, and other organic intermediates.
Beyond its reducing capabilities, borohydrides can also be used as reducing agents in the preparation of nanoparticles, metal hydrides, and other functional materials.
The applications of borohydrides extend beyond synthetic chemistry.
They have been explored in the development of fuel cells, hydrogen storage, and as additives in the production of wheat arabinoxylan, konjac glucomannan, and other polysaccharide-based materials.
Borohydrides can also be used in the crosslinking of biopolymers, such as larch arabinogalactan and carob galactomannan, for the creation of hydrogels and other biomaterials.
Optimizing borohydride research can be a complex undertaking, as the selection of the appropriate borohydride product and experimental protocol is crucial for achieving desired outcomes.
PubCompare.ai, a powerful AI-driven platform, can assist researchers in this endeavor by locating the best protocols from the literature, preprints, and patents, thereby enhancing the reproducibility and accuracy of their borohydride-related experiments.
With PubCompare.ai's tools, researchers can identify the most effective borohydride products and procedures, streamlining their research and unlocking new possibilities in organic synthesis, materials science, and beyond.
Whether you're working with sodium borohydride, exploring the versatility of borohydrides in organic reactions, or developing novel borohydride-based materials, PubCompare.ai can be a valuable resource to optimize your research and drive scientific progress.