Bpnt1 floxed mice were generated using a standard homologous recombination approach (Fig. S2A ). Briefly, we recombined the fourth and fifth exons of the Bpnt1 locus in 129/SvEv ES cells with a construct containing flanking LoxP sites and a neomycin resistance cassette. Cells resistant to neomycin were confirmed by PCR and Southern blotting, injected into blastocysts, and implanted into pseudopregnant females by the University of North Carolina Animal Models Core. Chimeric founders were identified by Southern blotting and PCR and crossed with B6.Cg-Tg(ACTFLPe)9205Dym/J mice (The Jackson Laboratory) expressing FLP recombinase to remove the neomycin cassette. Bpnt1+/fl mice were then backcrossed four generations into the C57BL/6J background, intercrossed, and maintained as Bpnt1fl/fl animals. To obtain intestine-specific knockouts, we first crossed B6.SJL-Tg(Vil-cre)997Gum/J mice (The Jackson Laboratory) expressing Cre recombinase under the control of the villin promoter with Bpnt1+/− animals to obtain Bpnt1+/−Vil-Cre+ double heterozygotes. These animals were then crossed to Bpnt1fl/fl mice to generate Bpnt1+/fl, Bpnt1−/fl, Bpnt1+/int, and Bpnt1−/int mice. Wild-type and conventional knockout Bpnt1 alleles were genotyped by multiplex PCR using the following primers: (i) 5′-cctatagtcctagcacttgagagg-3′, (ii) 5′-accaaagaacggagccggttggcg-3′, and (iii) 5′-aggtcggaaccctgttctctagtc-3′. Floxed Bpnt1 alleles were genotyped by PCR using the following primers: (i) 5′-cttgtggtttgggttgaccccttag-3′ and (ii) 5′-ctctagcccagtcagacatgtcag-3′. Villin-Cre expression was determined by PCR using the following primers: (i) 5′-gcggtctggcagtaaaaactatc-3′ and (ii) 5′-gtgaaacagcattgctgtcactt-3′. All animals unless otherwise noted were maintained on Purina 5058 natural products chow. Animals receiving supplemental iron were injected into the scruff of the neck weekly for a total of 3 wk with 5 mg of sterile Fe–dextran (Sigma). After 3 wk, mice were killed and analyzed as described above. Animals challenged with iron-deficient diets were maintained on normal Purina 5058 chow until the time of weaning (P23), at which point they were given either iron-deficient AIN-93G–defined chow with 2–6 ppm total iron or an identical AIN-93G supplemented with 200 ppm iron(II) sulfate (Harlan-Teklad TD.120105 and TD.120106, respectively). Mice were killed after 5 wk of dietary treatment and analyzed for hematological parameters as described above. Animal care and experiments were performed in accordance with the National Institutes of Health guidelines and approved by the Duke University Institutional Animal Care and Use Committee.
>
Chemicals & Drugs
>
Inorganic Chemical
>
Dietary Iron
Dietary Iron
Dietary Iron: An essential mineral critical for various physiological processes, including oxygen transport, energy production, and immune function.
Maintaining optimal dietary iron intake is crucial for overall health and preventing iron deficiency anemia.
This concise overview covers the key aspects of dietary iron, including its sources, absorption, and role in the body.
Leverage AI-driven research tools to streamline your investigations into dietary iron and identify the best approaches for your specific needs.
Maintaining optimal dietary iron intake is crucial for overall health and preventing iron deficiency anemia.
This concise overview covers the key aspects of dietary iron, including its sources, absorption, and role in the body.
Leverage AI-driven research tools to streamline your investigations into dietary iron and identify the best approaches for your specific needs.
Most cited protocols related to «Dietary Iron»
Alleles
Animal Model
Animals
Blastocyst
Cells
Chimera
Cre recombinase
Dextran
Diet
Dietary Iron
Exons
Females
FLP recombinase
Heterozygote
Homologous Recombination
Institutional Animal Care and Use Committees
Intestines
Iron
Mice, Laboratory
Multiplex Polymerase Chain Reaction
Natural Products
Neck
Neomycin
Oligonucleotide Primers
Sterility, Reproductive
Sulfates, Inorganic
villin
We recruited 44 individuals (95% male) with a chronic history of cocaine use, meeting the DSM-IV-TR criteria for cocaine dependence, and 44 matched healthy control volunteers (93% male) without a history of drug or alcohol dependence. The diagnosis of cocaine dependence was ascertained using the Structured Clinical Interview for DSM-IV, and these individuals are subsequently referred to as cocaine use disorder (CUD). None of the control participants had ever met DSM-IV-TR criteria for substance dependence; for further details see Supplementary Material . All participants provided written informed consent before they underwent a medical review and psychiatric screening. Exclusion criteria included major medical or neurological illness, lifetime history of a psychotic disorder, history of a traumatic head injury, or any contra-indications to MR-scanning. Dietary iron intake was calculated from the Food Frequency Questionnaire (http://www.srl.cam.ac.uk/epic/nutmethod/FFQ.shtml ). Diet-related variations in iron absorption were estimated using the algorithms developed by Hallberg and Hulthen.33 (link) All participants provided blood samples for the analysis of iron proteins in serum (that is, ferritin, iron, transferrin), hepcidin-25, acute inflammation (that is, C-reactive protein (CRP)) and haematological status. This study was approved by the National Research Ethics Committee (12/EE/0519; PI: KDE).
Full text: Click here
Alcoholic Intoxication, Chronic
Blood Proteins
Cocaine
Cocaine Dependence
Craniocerebral Trauma
C Reactive Protein
Diagnosis
Dietary Iron
Ethics Committees, Research
Ferritin
Food
Healthy Volunteers
Hematologic Tests
Hepcidin
Inflammation
Iron
Males
Pharmaceutical Preparations
Proteins
Psychotic Disorders
Serum
Substance Dependence
Transferrin
We used DESeq2 to find differentially expressed transcripts in control diet and iron-loaded diet samples for each sequencing depth. The FDR was adjusted to 0.05, and the other parameters were set to default. The number of overlapping differentially expressed transcripts in Trad-KAPA and 3’-LEXO was calculated. For 1, 2.5 and 5 million reads, the overlap between differentially expressed transcripts in subsampled pools and the initial 10 million read sample was computed. The log fold changes from DESeq2 were used to calculate the correlations between the two methods.
Full text: Click here
Diet
Dietary Iron
Birth
Diet
Dietary Iron
Dietary Modification
Drug Overdose
Eating
Fetal Blood
Fetus
Formalin
Freezing
Homo sapiens
Institutional Animal Care and Use Committees
Iron
Isoflurane
Liver
Mothers
Nitrogen
Paraffin
Patient Holding Stretchers
Perfusion
Placenta
Pregnancy
Rats, Long-Evans
Tissues
Vagina
Woman
Protocol full text hidden due to copyright restrictions
Open the protocol to access the free full text link
Childbirth
Diet
Dietary Iron
Iron
Patient Holding Stretchers
Pregnant Women
Most recents protocols related to «Dietary Iron»
The research staff recorded the sociodemographic and lifestyle data of the participants during a personal interview using specific questionnaires, including maternal age, baseline body mass index (BMI), smoking habit, ethnicity, parity, pregnancy planning, and use of hormonal contraceptives. The educational level and occupational status of women and their partners were also registered. The family’s socioeconomic status (SES) was calculated from the sociodemographic data of participants and their partners, including educational level and occupational status. Dietary assessment was done using a short food frequency questionnaire (FFQ) validated in our population [22 (link)]. Food groups assessed included total meat, red and processed meat, fish, fruits, vegetables, legumes, and dairy products as grams per day (g/day). From this information, energy intake (kcal/day) and nutrients (g/day or mg/day) were calculated using the REGAL (Répertoire Général des Aliments) food composition table [23 ], complemented by a Spanish food composition table [24 ]. As for the nutrient intake, protein, fibre, vitamin C, calcium, and dietary iron were assessed. Detailed information is available in Aparicio et al. [25 ]. Information from the FFQ allowed us to calculate the percentage of adherence to the Mediterranean diet, considered a high–quality dietary pattern [25 , 26 ]. Extended information on data collection can be found elsewhere [8 (link), 20 (link)].
Blood samples were taken on GW12 to perform blood and genetic tests. Haematological parameters (Hb and MCV), some specific biochemical markers (SF and C-reactive protein [CRP]), and genetic mutations of the HFE gene (C282Y, H63D and S65C) were performed.
Blood samples were taken on GW12 to perform blood and genetic tests. Haematological parameters (Hb and MCV), some specific biochemical markers (SF and C-reactive protein [CRP]), and genetic mutations of the HFE gene (C282Y, H63D and S65C) were performed.
Full text: Click here
Ascorbic Acid
BLOOD
Calcium, Dietary
Contraceptive Agents
C Reactive Protein
Dairy Products
Diet
Diet, Mediterranean
Dietary Iron
Ethnicity
Fabaceae
Fibrosis
Fishes
Food
Fruit
Genetic Testing
Hispanic or Latino
Index, Body Mass
Meat
Mutation
Nutrient Intake
Nutrients
Pregnancy
Proteins
Vegetables
Data were double entered using Epi-data 3.1. Data were cleaned, coded, checked for missing and outliers, and analyzed using Stata 14 (College Station, Texas 77845 USA). Frequencies, percentages, summary measures and tables were used to describe and present the descriptive information of respondents. The MUAC is a much simpler anthropometric measure than the BMI, as its use eliminates the need for expensive equipment, such as height charts and scales, and the need for calculations. It is also much easier to perform on a patient who is acutely unwell, bed bound or sedentary. Another important advantage of using MUAC is that there is minimal change in the MUAC during pregnancy, so it may be a better indicator of pre-pregnancy body fat and nutrition than the BMI. The outcome variable (undernutrition) was dichotomized as undernutrition (coded as 1) and normal (coded as 0). Poisson regression analysis models with a robust variance estimate were fitted to identify predictors of undernutrition. Next, the binary analysis variables with a p< 0.25 were entered into the adjusted log-binomial models. Results were presented using the crude prevalence ratio (CPR) and adjusted prevalence ratio (aPR). Akaike’s information criterion (AIC) and Bayesian information criterion (BIC) were used to test for model fitness. The goodness-of-fit was assessed using the Pearson chi-square and deviance tests, with the statistical significance level at alpha = 5%. The explanatory variables were examined for multi-collinearity before taking them into the multivariable model using a correlation matrix for the regression coefficients, the standard errors, and the variance inflation factor value.
The wealth index was employed to estimate the economic level of families. The wealth dispersion was generated by applying the principal component analysis (PCA). The index was calculated based on the ownership of latrines, agricultural land and size, selected household assets, livestock quantities, and source of drinking water, a total of 41 household variables. The previous paper [28 ] described nutritional knowledge and attitudes toward consumption of an iron-rich diet using the Likert scale applying the PCA; the factor scores were totaled and classified into tertiles. Women’s autonomy was evaluated using seven validated questions adopted from the Ethiopian Demographic Health Survey [34 ]. For each question, the response was coded as "one" when the decision was made by the woman alone or jointly with her husband, or "zero" otherwise. The detailed description has been given elsewhere in a previous papers [21 , 23 (link), 24 (link)].
The wealth index was employed to estimate the economic level of families. The wealth dispersion was generated by applying the principal component analysis (PCA). The index was calculated based on the ownership of latrines, agricultural land and size, selected household assets, livestock quantities, and source of drinking water, a total of 41 household variables. The previous paper [28 ] described nutritional knowledge and attitudes toward consumption of an iron-rich diet using the Likert scale applying the PCA; the factor scores were totaled and classified into tertiles. Women’s autonomy was evaluated using seven validated questions adopted from the Ethiopian Demographic Health Survey [34 ]. For each question, the response was coded as "one" when the decision was made by the woman alone or jointly with her husband, or "zero" otherwise. The detailed description has been given elsewhere in a previous papers [21 , 23 (link), 24 (link)].
Full text: Click here
Body Fat
Dietary Iron
Households
Husband
Livestock
Malnutrition
Patients
Pregnancy
Woman
The present study is a double-blind, randomized, parallel, placebo-controlled intervention study that has been carried out at two separate trial sites for non-anemic male and female endurance athletes. The reason for selecting different sites for male and female participants was simply based on the availability of the athletic subjects. However, each trial site followed a set recruitment strategy as per study protocols. Participants were asked to complete a health history form, and to be eligible, the following criteria had to be met: (i) no major illness, (ii) 20 years of age or over, (iii) no history of iron deficiency (hemoglobin:13.5–14.5 g/dL (for male); 11.5–12.5 g/dL (for female), (iv) no previous history of known fatigue-related pathology, (iv) not under any medication/taking any iron supplements, (v) no history of somatic, or sleep disorder, and (vi) reported to be regularly menstruating (female participants only). Exclusion criteria were: recent surgery, inflammation or pain (chronic or acute), smokers and having a high habitual consumption of caffeine (>100 mg/day) and alcohol (>20 g/day); pregnancy, and breastfeeding. Also, the researchers used an orthopedic questionnaire to confirm the athlete's eligibility to participate in the study.
Fifty-one healthy adult male athletes with regular exercise habits such as professional soccer and futsal player (Criacao Shinjuku, Tokyo, Japan) were recruited for this study. Participants were evaluated at Otsuma Women's University, Tokyo, Japan trial site-1 between October 2019 and November 2019 (average temperature: 18 °C; average humidity: 78%) in an intervention study to determine the influence of dietary iron supplements on fatigue, sweating, and lifestyle profiles of these professional male athletes. The study protocol was approved (No. 2019-035-2) by the Otsuma Women's University Life Science Research Ethics Committee. Also, forty-four healthy adult female athletes with sweating habits and hot yoga experience were evaluated at Nippon Sport Science University, Tokyo, Japan trial site-2 between October 2019 and November 2019 (average temperature: 17.3 °C; average humidity: 77.2%). Sweating habits indicate the fitness level of the athletes. The athletes who are very fit sweat more than their less-fit counterparts during a workout because they need to generate more heat to maximize their evaporative cooling capacity. The study was approved (No. 018-H040) by the Ethics Committee at the Nippon Sport Science University, Tokyo, Japan.
The study procedures were conducted according to the guidelines and ethical standards laid out in the Helsinki Declaration. Procedures were verbally explained to the participants and informed consent was signed by all participating athletes. All participants received detailed information on the purpose of the study (including health hazards, privacy protection, and data management). The study compliance was assured, and the fidelity of the informed intervention was checked.
Fifty-one healthy adult male athletes with regular exercise habits such as professional soccer and futsal player (Criacao Shinjuku, Tokyo, Japan) were recruited for this study. Participants were evaluated at Otsuma Women's University, Tokyo, Japan trial site-1 between October 2019 and November 2019 (average temperature: 18 °C; average humidity: 78%) in an intervention study to determine the influence of dietary iron supplements on fatigue, sweating, and lifestyle profiles of these professional male athletes. The study protocol was approved (No. 2019-035-2) by the Otsuma Women's University Life Science Research Ethics Committee. Also, forty-four healthy adult female athletes with sweating habits and hot yoga experience were evaluated at Nippon Sport Science University, Tokyo, Japan trial site-2 between October 2019 and November 2019 (average temperature: 17.3 °C; average humidity: 77.2%). Sweating habits indicate the fitness level of the athletes. The athletes who are very fit sweat more than their less-fit counterparts during a workout because they need to generate more heat to maximize their evaporative cooling capacity. The study was approved (No. 018-H040) by the Ethics Committee at the Nippon Sport Science University, Tokyo, Japan.
The study procedures were conducted according to the guidelines and ethical standards laid out in the Helsinki Declaration. Procedures were verbally explained to the participants and informed consent was signed by all participating athletes. All participants received detailed information on the purpose of the study (including health hazards, privacy protection, and data management). The study compliance was assured, and the fidelity of the informed intervention was checked.
Full text: Click here
Adult
Athletes
Caffeine
Deficiency, Iron
Dietary Iron
Dietary Supplements
Diploid Cell
Eligibility Determination
Ethanol
Ethics Committees
Ethics Committees, Research
Fatigue
Females
Hemoglobin
Humidity
Inflammation
Iron
Males
Operative Surgical Procedures
Pain
Pharmaceutical Preparations
Placebos
Pregnancy
Professional Athletes
Sleep Disorders
Sweat
Yoga
Participants were divided into two groups at each trial site and were assigned to order treatment groups according to a randomization plan of equal block size with a 1:1 allocation ratio to receive either iron supplementation or placebo by an independent researcher. The allocation remained concealed to participants, general instructors, statistical analysts, and principal investigators until the end of the trial. The coding of the groups was revealed to researchers only after all measurements were completed and reported. Participants were instructed to consume the treatment once a day, either before or after meals for four consecutive weeks. The treatments were packaged in the sachet (1.5 g as granules) and were identical in appearance, calorie value (5.7 kcal) taste, and raw materials (dextrin, trehalose, and enzymatically degraded guar gum as stabilizer). The dietary iron sachet contains 3.6 mg of ferric pyrophosphate in granules along with 1.37 g carbohydrates and 1.8 mg sodium (Taiyo Kagaku Cookin Supplement Fe; SunActive Fe®), while the placebo was dextrin (carbohydrates: 1.42 g). The specifications of raw materials and nutrient content of iron and placebo granules supplement were confirmed by an independent accredited laboratory. Compliance was assessed at every visit by counting the number of remaining study product sachets returned by the subjects and using a diary system.
Full text: Click here
Carbohydrates
Cytoplasmic Granules
Dextrin
Dietary Iron
Dietary Supplements
guar gum
Iron
magnesium pyrophosphate
Nutrients
Placebos
Sodium
Sunactive Fe
Taste
Trehalose
The 4-week length of the study was based on the time needed to evaluate non-specific symptoms such as fatigue [9 (link)]. The training program (futsal/soccer practice) and exercise regimen for participating male athletes were continued for 4 consecutive weeks (site-1). While the female athletes (site-2) were instructed to execute their habitual exercise at least once a week for about 60 min duration with sweating. Featured exercises performed during the 4 weeks study period were mainly hot yoga, dance exercise, martial art exercise, resistance movements, underwater exercise/swimming, and running/walking. Participants of both groups were asked to record their exercise to ensure that all participants remained in identical physical energy balance during the fitness training during the four weeks study period.
A schematic protocol illustration is presented inFig. 1 . Participating male and female athletes were registered for the study at two separate sites after confirmation of their eligibility according to set inclusion/exclusion criteria. All participants were asked to visit their respective testing laboratories at trial sites three times during the four-week study period. During the participant's initial visit (baseline) to the laboratory, a self-completed Profile of Mood State (POMS) questionnaire, and an exercise and well-being related Fatigue-Sweat questionnaire were administrated to male athletes to assess the effect of dietary iron supplementation on quality of life including fatigue and mood symptoms by assessing a range of associated domains. On the other hand, the state level of fatigue and related subscale subjective lifestyle quality parameters including sweating behavior among female athletes were measured with a visual analog scale (VAS) questionnaire. The two different questionnaires, VAS and POMS were used for female and male athletic subjects, respectively, because the data collection was based on the required intensities of sweating exercise and metabolism behavior differences among female and male athletes. However, the purpose and questions asked in both questionnaires were interrelated to retain the identical outcomes of the study. Each participant completed the study questionnaires at baseline, after two weeks (mid-point), and after four weeks of the study (end-point). Mood, stress, and sweat behavior were analyzed using the scores obtained from questionnaires.Fig. 1 ![]()
The anthropometric, body temperature and heart rate were measured for each participant during every laboratory visit. Noninvasive measurement of hemoglobin levels, which measures estimated hemoglobin levels in peripheral blood vessels was performed to scientifically monitor the participating athletes' conditioning on each visit to the laboratory during the study period. Furthermore, to determine the changes in stress markers during the study, saliva samples were collected at the beginning and end of the study, in order, to measure the salivary cortisol, salivary α-amylase, and salivary-immunoglobulin A concentrations.
A schematic protocol illustration is presented in
Schematic illustration of experimental design of study protocol and procedures.
Full text: Click here
Athletes
Blood Vessel
Body Temperature
Dietary Iron
Eligibility Determination
Fatigue
Females
Hemoglobin
Hydrocortisone
Immunoglobulin A
Males
Metabolism
Mood
Movement
Physical Examination
Rate, Heart
Saliva
Salivary alpha-Amylases
Sweat
Treatment Protocols
Visual Analog Pain Scale
Yoga
Top products related to «Dietary Iron»
Sourced in United States
The TD.80396 is a piece of laboratory equipment. It is used for performing specific tasks or functions within a laboratory setting. However, a detailed description of its core function while maintaining an unbiased and factual approach is not available at this time.
Sourced in United States
Carbonyl iron is a type of iron powder produced through the thermal decomposition of iron pentacarbonyl. It is characterized by its high purity, uniform particle size, and spherical shape. Carbonyl iron is used as a raw material in various industrial applications, including the production of magnetic components, electromagnetic shielding materials, and dietary supplements.
Sourced in United States, Austria, Japan, Belgium, United Kingdom, Cameroon, China, Denmark, Canada, Israel, New Caledonia, Germany, Poland, India, France, Ireland, Australia
SAS 9.4 is an integrated software suite for advanced analytics, data management, and business intelligence. It provides a comprehensive platform for data analysis, modeling, and reporting. SAS 9.4 offers a wide range of capabilities, including data manipulation, statistical analysis, predictive modeling, and visual data exploration.
Sourced in United States, China, Germany, United Kingdom, Canada, Japan, France, Italy, Montenegro, Spain
Female C57BL/6 mice are laboratory rodents commonly used in scientific research. They are genetically inbred and have a well-characterized genetic background. These mice are widely utilized as animal models in various fields of study, including immunology, oncology, and neuroscience.
The Standard Rodent Diet is a complete and balanced feed formulated to meet the nutritional requirements of rodents. It provides essential vitamins, minerals, and macronutrients necessary for maintaining the health and well-being of laboratory rodents.
Fxnki/ko (C57/BL6) is a laboratory mouse strain genetically modified to have a targeted inactivation of the Fxnki gene. This strain is commonly used in biomedical research to study the function of the Fxnki gene and its role in various physiological processes.
The Two ppm (TD.09127) Fe diet is a laboratory animal diet formulated to contain 2 parts per million (ppm) of iron. It is designed to provide a controlled level of iron in the diet for research purposes.
Sourced in United States
Microcapillary tubes are small, thin glass or plastic tubes designed for the handling and transfer of small volumes of liquids. They are commonly used in various laboratory applications where precise fluid handling is required.
Sourced in United States
The TD.80394 is a laboratory instrument designed for conducting analytical measurements. It serves as a core function in various scientific applications. The detailed specifications and intended use of this product are not available at this time.
Sourced in United States, Montenegro, United Kingdom, Germany, Australia, China, Canada
C57BL/6 is a widely used inbred mouse strain. It is a robust, readily available laboratory mouse model.
More about "Dietary Iron"
Dietary Iron: An essential mineral vital for various physiological processes, including oxygen transport, energy production, and immune function.
Maintaining optimal dietary iron intake is crucial for overall health and preventing iron deficiency anemia.
This comprehensive overview covers the key aspects of dietary iron, including its sources, absorption, and role in the body.
Iron is a critical component of hemoglobin, the protein in red blood cells responsible for carrying oxygen throughout the body.
It also plays a key role in energy metabolism, enabling the conversion of food into usable energy.
Additionally, iron supports the immune system by aiding in the production of white blood cells and other immune cells.
Dietary iron can be obtained from a variety of food sources, including red meat, poultry, seafood, legumes, fortified grains, and leafy green vegetables.
The absorption of iron is influenced by a number of factors, such as the form of iron (heme vs. non-heme), the presence of enhancers (e.g., vitamin C), and the individual's iron status.
Researchers have utilized advanced tools like PubCompare.ai to streamline their investigations into dietary iron.
This AI-driven platform helps identify reproducible and accurate protocols from literature, preprints, and patents, and enables comparisons to find the best products and approaches.
By leveraging these cutting-edge research tools, scientists can optimize their studies and achieve more reliable results.
Experiments conducted on female C57BL/6 mice, a common model organism, have provided valuable insights into the role of dietary iron.
Studies using standard rodent diets, such as TD.09127 (Two ppm Fe diet), have helped elucidate the impact of iron intake on physiological processes.
Additionally, the use of techniques like microcapillary tubes and analysis with SAS 9.4 software have contributed to our understanding of iron metabolism and its implications for human health.
Maintaining a healthy iron balance is essential for overall well-being.
By understanding the sources, absorption, and functions of dietary iron, individuals can make informed choices to optimize their iron intake and prevent deficiencies.
Leveraging the latest research tools and technologies, like those offered by PubCompare.ai, can help streamline the investigation of dietary iron and lead to more effective strategies for improving human health.
Maintaining optimal dietary iron intake is crucial for overall health and preventing iron deficiency anemia.
This comprehensive overview covers the key aspects of dietary iron, including its sources, absorption, and role in the body.
Iron is a critical component of hemoglobin, the protein in red blood cells responsible for carrying oxygen throughout the body.
It also plays a key role in energy metabolism, enabling the conversion of food into usable energy.
Additionally, iron supports the immune system by aiding in the production of white blood cells and other immune cells.
Dietary iron can be obtained from a variety of food sources, including red meat, poultry, seafood, legumes, fortified grains, and leafy green vegetables.
The absorption of iron is influenced by a number of factors, such as the form of iron (heme vs. non-heme), the presence of enhancers (e.g., vitamin C), and the individual's iron status.
Researchers have utilized advanced tools like PubCompare.ai to streamline their investigations into dietary iron.
This AI-driven platform helps identify reproducible and accurate protocols from literature, preprints, and patents, and enables comparisons to find the best products and approaches.
By leveraging these cutting-edge research tools, scientists can optimize their studies and achieve more reliable results.
Experiments conducted on female C57BL/6 mice, a common model organism, have provided valuable insights into the role of dietary iron.
Studies using standard rodent diets, such as TD.09127 (Two ppm Fe diet), have helped elucidate the impact of iron intake on physiological processes.
Additionally, the use of techniques like microcapillary tubes and analysis with SAS 9.4 software have contributed to our understanding of iron metabolism and its implications for human health.
Maintaining a healthy iron balance is essential for overall well-being.
By understanding the sources, absorption, and functions of dietary iron, individuals can make informed choices to optimize their iron intake and prevent deficiencies.
Leveraging the latest research tools and technologies, like those offered by PubCompare.ai, can help streamline the investigation of dietary iron and lead to more effective strategies for improving human health.