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2,3-dihydroxybenzoic acid

2,3-Dihydroxybenzoic acid is an organic compound with the chemical formula C7H6O3.
It is a derivative of benzoic acid and is characterized by the presence of two hydroxyl groups attached to the benzene ring at positions 2 and 3.
This compound has been the subject of research optimization efforts, as it has potential applications in various fields, such as pharmaceuticals and materials science.
Researchers can explore the available protocols from literature, preprints, and patents using the AI-driven platform PubCompare.ai, which enhances reproducibility and accuracy through intelligent comparisons to identify the best methodologies and products.
This platform can streamline the research process and leverage the power of AI-enhanced discoverability to unlock new insights and optimize the study of 2,3-dihydroxybenzoic acid.

Most cited protocols related to «2,3-dihydroxybenzoic acid»

1
Analysis of IgG N-glycans by HILIC-MS
Cited 17 times
Before MS analysis of each glycan peak, the 2-AB labeled IgG N-glycan pool was fractionated by hydrophilic interaction high performance liquid chromatography (HILIC) on a 100 × 2.1 mm i.d., 1.7 μm BEH particles column using a linear gradient of 75–62% acetonitrile with 100 mM ammonium formate, pH 4.4, as solvent A and acetonitrile as solvent B. UltiMate Dual Gradient LC system (Dionex, Sunnyvale, CA) controlled by Chromeleon software and connected to FP-2020 Plus fluorescence detector (Jasco, Easton, MD) was used. To obtain the same separation as with UPLC system, flow was adjusted to 0.3 ml/min and analytical run time was prolonged to 60 min. Collected fractions were dried by vacuum centrifugation and resuspended in water.
Nano-LC-ESI-MS/MS. MS analysis of the collected glycan fractions was performed using an Ultimate 3000 nano-LC system (Dionex/LC Packings, Amsterdam, The Netherlands) equipped with a reverse phase trap column (C18 PepMap 100Å, 5 μm, 300 μm × 5 mm; Dionex/LC Packings) and a nano column (C18 PepMap 100Å, 3 μm, 75 μm × 150 mm; Dionex/LC Packings).
The column was equilibrated at room temperature with eluent A (0.1% formic acid in water) at a flow rate of 300 nL/min. For fractions with disialylated glycans, extra 0.04% of trifluoroacetic acid was added to the eluent A. After injection of the samples, a gradient was applied to 25% eluent B (95% acetonitrile) in 15 min and to 70% eluent B at 25 min followed by an isocratic elution with 70% eluent B for 5 min. The eluate was monitored by UV absorption at 214 nm. The LC system was coupled via an online nanospray source to an Esquire HCTultra ESI-IT-MS (Bruker Daltonics, Bremen, Germany) operated in the positive ion mode. For electrospray (1100–1250 V), stainless steel capillaries with an inner diameter of 30 μm (Proxeon, Odense, Denmark) were used. The solvent was evaporated at 170 °C employing a nitrogen stream of 7 L/min. Ions from m/z 500 to 1800 were registered. Automatic fragment ion analysis was enabled, resulting in MS/MS spectra of the most abundant ions in the MS spectra. Glycan structures were assigned using GlycoWorkbench (41 (link)).
MALDI-TOF-MS. 2-AB labeled glycan fractions were spotted onto an AnchorChip target plate (Bruker Daltonics, Bremen, Germany). Subsequently 1 μl of 5 mg/ml 2,5-dihydroxybenzoic acid in 50% acetonitrile was applied on top of each sample and allowed to dry at room temperature. MALDI-TOF-MS was performed on an UltrafleX II mass spectrometer (Bruker Daltonics). Calibration was performed on a peptide calibration standard. Spectra were acquired in reflector positive mode over the m/z range from 700 to 3500 Da for a total of 2000 shots. Glycan structures were assigned using GlycoWorkbench (41 (link)).
Pučić M., Knežević A., Vidič J., Adamczyk B., Novokmet M., Polašek O., Gornik O., Šupraha-Goreta S., Wormald M.R., Redžić I., Campbell H., Wright A., Hastie N.D., Wilson J.F., Rudan I., Wuhrer M., Rudd P.M., Josić D, & Lauc G. (2011). High Throughput Isolation and Glycosylation Analysis of IgG–Variability and Heritability of the IgG Glycome in Three Isolated Human Populations. Molecular & Cellular Proteomics : MCP, 10(10), M111.010090.
Publication 2011
2,3-dihydroxybenzoic acid acetonitrile Capillaries Centrifugation Fluorescence formic acid formic acid, ammonium salt High-Performance Liquid Chromatographies Hydrophilic Interactions Ions Nitrogen Peptides Polysaccharides Solvents Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Stainless Steel Tandem Mass Spectrometry Trifluoroacetic Acid Vacuum
2
Extraction and Analysis of Human Milk Oligosaccharides
Cited 13 times
OS were extracted from human milk obtained from the milk banks in San Jose, CA and Austin, TX. The extraction method was the same as in our previous publication.27 (link), 45 (link) Sodium borohydride (98%) and 2,5-dihydroxybenzoic acid (DHB) were purchased from Sigma-Aldrich (St. Louis, MO). Nonporous graphitized carbon cartridges (GCC, 150mg bed weight, 4mL cartridge volume) were bought from Alltech (Deerfield, IL). Standard HMOs were purchased from Dextra Laboratories (Earley Gate, UK). α(1-2)-Fucosidase was from EMD Calbiochem (La Jolla, CA). β(1-3)-Galactosidase was from New England Biolab (Beverly, MA). β(1-4)-Galactosidase was from ProZyme (San Leandro, CA). α(1-3,4)-Fucosidase was from Sigma-Aldrich (St. Louis, MO). All other reagents were of analytical or HPLC grade.
Wu S., Tao N., German J.B., Grimm R, & Lebrilla C.B. (2010). The development of an annotated library of neutral human milk oligosaccharides. Journal of proteome research, 9(8), 4138-4151.
Publication 2010
2,3-dihydroxybenzoic acid austin Carbon Fucosidase Galactosidase High-Performance Liquid Chromatographies Milk, Human sodium borohydride
3
Isolation and Analysis of Human Milk Oligosaccharides
Cited 12 times
The OS used in this study are from pooled human milk provided by milk banks in San Jose, CA and Austin, TX. HMOs were isolated from the milk using a previously described procedure involving defatting, chloroform/methanol extraction, ethanol precipitation, and evaporation.6 (link) A sample enrichment step with solid phase extraction (SPE) employing graphitized carbon cartridge (GCC) was used before the analysis. GCC (150 mg bed weight, 4mL volume) were purchased from Alltech (Deerfield, IL). Sodium borohydride (98%) and 2, 5-dihydroxybenzoic acid (DHB) were obtained from Sigma–Aldrich (St. Louis, MO). Standard HMOs were purchased from Dextra Laboratories (Earley Gate, UK). α(1–2)-Fucosidase was obtained from EMD CALBIOCHEM (La Jolla, CA), β(1–3)-galactosidase and α(2–3)-neuraminidase from New England Biolab (Beverly, MA), β(1–4)-galactosidase from ProZyme (San Leandro, CA), and α(1–3,4)-fucosidase from Sigma–Aldrich (St. Louis, MO). The non-selective sialidase was purified and provided by Prof. David Mills from the Department of Viticulture and Enology in UC Davis. All reagents are of analytical or HPLC grade.
Wu S., Grimm R., German J.B, & Lebrilla C.B. (2011). Annotation and Structural Analysis of Sialylated Human Milk Oligosaccharides. Journal of proteome research, 10(2), 856-868.
Publication 2011
2,3-dihydroxybenzoic acid austin Carbon Chloroform Ethanol Fucosidase Galactosidase High-Performance Liquid Chromatographies Methanol Milk Milk, Human Neuraminidase sodium borohydride Solid Phase Extraction
4
Single-Molecule Bacterial Translation Initiation
Cited 9 times
We prepared fluorescently-labeled 30S (Cy3 or Cy3B) and 50S (Cy5) subunits, translation factors, S1, mRNA, labeled (Cy2) and unlabeled tRNA as described previously14 (link),22 (link),23 (link). To assemble 30S PICs, we mixed 0.25 µM Cy3-30S pre-incubated with stoichiometric S1, 1 µM IF2, 1 µM fMet-tRNAfMet, 1 µM biotinylated mRNA, and 4 mM GTP in a previously described Tris-based polymix buffer system without reducing agents23 (link), and subsequently incubated this mixture at 37 °C for 5 minutes. The Mg2+ concentration in all buffers was 5 mM.
Prior to surface immobilization, we diluted assembled PICs in polymix buffer containing 1 µM IF2, 1 µM fMet-tRNAfMet, and 4 mM GTP23 (link). We next immobilized these diluted PICs on a neutravidin-derivatized quartz slide, and washed with polymix buffer containing 1 µM IF2, 1 µM fMet-tRNAfMet, 4 mM GTP, 1 mM Trolox (for Cy5 stabilization), and an oxygen-scavenging system (2.5 mM 3,4 dihydroxybenzoic acid and 250 nM protocatechuate dioxygenase24 (link)). To initiate translation, we delivered 50 nM Cy5-50S, 1 µM IF2, 20–100 nM EF-G, 20–100 unlabeled nM ternary complex, 20 nM Phe-(Cy2)tRNAPhe (where applicable), and antibiotics (where applicable, in specified concentrations) in the polymix wash buffer using a controlled syringe pump. We prepared Phe-tRNAPhe and Lys-tRNALys ternary complexes immediately prior to use as previously described23 (link).
Aitken C.E, & Puglisi J.D. (2010). Following the intersubunit conformation of the ribosome during translation in real time. Nature structural & molecular biology, 17(7), 793-800.
Publication 2010
2,3-dihydroxybenzoic acid Antibiotics, Antitubercular Buffers Lysine-Specific tRNA neutravidin Oxygen Phenylalanine-Specific tRNA Protein Subunits Quartz RNA, Messenger Syringes Transfer RNA Trolox C Tromethamine
5
Synthesis and Characterization of Arylquin Inhibitors
Cited 7 times
Nutlin-3a, an inhibitor of MDM2 that is reported to bind directly to MDM2, release, stabilize and activate p53 10 (link), was acquired from Cayman Chemical Company. Brefeldin A, N-benzyloxycarbonyl-Val-Ala-Asp(O-Me) fluoromethyl ketone(zVAD-fmk) and other chemicals were purchased from Sigma Aldrich or Fisher Scientific or were synthesized according to literature procedures. The synthesis of Arylquin 1, which utilized 4-(N,N-dimethylamino)-2-aminobenzaldehyde in a Friedländer condensation with 2-fluorophenylacetontrile 15 , and other heterocyclic families is described in Supplementary Note. The condensation of 2-amino-4-(N,N-dimethylamino)benzaldehyde with 2-(2-fluorophenyl)acetyl chloride secured 7-(dimethylamino)-3-(2-fluorophenyl)quinolin-2(1H)-one, and treatment with Lawesson's reagent 16 provided 7-(dimethylamino)-3-(2-fluorophenyl)quinoline-2(1H)-thione. S-alkylation of this intermediate with (+)-biotinyl-iodoacetamidyl-3,6-dioxaoctanediamine led to biotinylated Arylquin 9 (Supplementary Note). Solvents were used from commercial vendors without further purification unless otherwise noted. Nuclear magnetic resonance spectra were determined on a Varian instrument (1H, 400MHz; 13C, 100Mz). High resolution electrospray ionization (ESI) mass spectra were recorded on a LTQ-Orbitrap Velos mass spectrometer (Thermo Fisher Scientific, Waltham, MA, USA). The FT resolution was set at 100,000 (at 400 m/z). Samples were introduced through direct infusion using a syringe pump with a flow rate of 5 µL/min. MALDI mass spectra were obtained on a Bruker Utraflexstreme time-of-flight mass spectrometer (Billerica, MA), using DHB (2,5-dihydroxybenzoic acid) matrix. Purity of compounds was established by combustion analyses by Atlantic Microlabs, Inc., Norcross, GA. Compounds were chromatographed on preparative layer Merck silica gel F254 unless otherwise indicated.
Burikhanov R., Sviripa V.M., Hebbar N., Zhang W., Layton W.J., Hamza A., Zhan C.G., Watt D.S., Liu C, & Rangnekar V.M. (2014). Arylquins Target Vimentin to Trigger Par-4 Secretion for Tumor Cell Apoptosis. Nature chemical biology, 10(11), 924-926.
Publication 2014
2,3-dihydroxybenzoic acid 2-aminobenzaldehyde acetyl chloride Alkylation Anabolism Arylquin 1 benzaldehyde benzyloxycarbonyl-valyl-alanyl-aspartic acid benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone Brefeldin A Caimans Ketones Lawesson's reagent Magnetic Resonance Imaging Mass Spectrometry MDM2 protein, human nutlin-3A quinoline Silica Gel Solvents Spectrometry, Mass, Electrospray Ionization Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Syringes Thiones

Most recents protocols related to «2,3-dihydroxybenzoic acid»

1
MALDI Imaging of Frozen Tissue
Fresh frozen tissue collection, matrix spraying, data acquisition and MALDI imaging were performed as described previously [17 (link)]. The matrix solution used was 20 mg/mL 5-dihydroxybenzoic acid (#149357-20G Sigma-Aldrich Inc, Missouri, USA) in 100% acetone and 0.1% trifluoroacetic acid (#302031 Sigma). The tissue was scanned with both MS and TIMS settings at a resolution of 20 μm. The MS settings were: scan range 20–2500 m/z in positive MS scan mode. The TIMS settings were: 1/K0 0–8 − 1.89 V×s/cm2, ramp time of 200 ms, acquisition time of 20 ms, duty cycle = −10%, and ramp rate of 4.85 Hz. Acquired raw data were initially processed with SCiLS lab 2021a (Bruker Scientific LLC, Billerica, MA, USA) and the file was exported to Metaboscape 2021b (Bruker, USA) for annotations and further downstream analysis.
Yadav M., Chaudhary P.P., D’Souza B.N., Ratley G., Spathies J., Ganesan S., Zeldin J, & Myles I.A. (2023). Diisocyanates influence models of atopic dermatitis through direct activation of TRPA1. PLOS ONE, 18(3), e0282569.
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Publication 2023
2,3-dihydroxybenzoic acid Acetone Freezing HAVCR1 protein, human Radionuclide Imaging Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Tissues Trifluoroacetic Acid
2
Spectroscopic Analysis of Peptide Compounds
All electronic abosorption spectra were obtained on either a Varian Cary 50 Bio spectrophotometer in a 2 ml quartz cuvette or a NanoDrop OneC between 200 nm and 800 nm. Fluorescence spectra was obtained on an Agilent (Santa Clara, CA, USA) Cary Eclipse Fluorescence Spectrophotometer in a 2‐ml cuvette between 565 nm and 800 nm. Mass spectrometry data were acquired on a Shimadzu (Columbia, MD, USA) LC‐MS 8040 and/or a Bruker Autoflex III Smartbeam matrix‐assisted laser desorption/ionization time of flight (MALDI‐TOF) using alpha‐cyano‐4‐hydroxycinnamic acid or dihydroxybenzoic acid as matrix. Circular dichroism was performed in a 200‐μl quartz cuvette on an Applied Photophysics Chirascan VX instrument. Cell assays were prepared and ran using a Memmert iso150 Incubator and Molecular Devices FlexStation 3. Cell assays were run using a Ready‐to‐Assay OT receptor cell kit (Millipore Sigma HTS090RTA) for Calcium Flux FLIPR Assays. Peptides were prepared on a CEM Liberty Blue automated microwave peptide synthesizer (CEM Corporation) and cleaved from resin using a CEM Razor rapid peptide cleavage system in 95% TFA containing 2.5% triisopropylsilane and 2.5% water for 40 min at 40°C. Peptides were purified using an Agilent 1200 reverse‐phase high‐performance liquid chromatography (RP‐HPLC). Products were dried on a 1 L Labconco FreeZone lyophilizer.
Asker M., Krieger J., Liles A., Tinsley I.C., Borner T., Maric I., Doebley S., Furst C.D., Börchers S., Longo F., Bhat Y.R., De Jonghe B.C., Hayes M.R., Doyle R.P, & Skibicka K.P. (2023). Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects. Diabetes, Obesity & Metabolism, 25(3), 856-877.
Publication 2023
2,3-dihydroxybenzoic acid alpha-cyano-4-hydroxycinnamic acid Biological Assay Calcium Cells Chromatography, Reversed-Phase Liquid Circular Dichroism Cytokinesis Fluorescence Mass Spectrometry Medical Devices Microwaves Peptides Quartz Resins, Plant Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
3
Peptide Synthesis and Labeling Protocol
All materials were used according to the manufacturer's instructions unless otherwise noted. The following were purchased from Sigma‐Aldrich, St. Louis, MO, USA: acetonitrile (MeCN), methanol (MeOH), triethylamine (TEA), dimethyl sulphoxide (DMSO), diethyl ether, cyanocobalamin (B12), triisopropylsilane, 1,1′‐carbonyl‐di‐(1,2,4‐trizole), n‐methyl‐pyrrolidone, 1‐ethyl‐3‐(3‐dimethylaminopropyl) carbodiimide, 1‐hydroxybenzo‐triazole and dihydroxybenzoic acid. The following were purchased from CEM Corporation, Matthews, NC, USA: Fmoc‐Rink Amide Protide non‐preloaded resin (LL), N,N′‐diisopropylcarbodiimide, ethyl cyanohydroxyiminoacetate (Oxyma), Fmoc protected amino acids: Asn(Trt); Gln(OtBu); Tyr(tBu); and Trp(Boc). The following were purchased from VWR, Radnor, PA, USA: 7‐trifloroacetic acid (TFA) and dimethylformamide (DMF). The following was purchased from BroadPharm, San Diego, CA, USA: sulpho‐DBCO‐amine. The following was purchased from Thermo Fisher, Waltham, MA, USA: AlexaFluor 564 (DBCO‐AF546). The following was purchased from Lumiprobe: Sulfo‐cyanine5 NHS ester. The following was purchased from Lumiprobe, Hunt Valley, MD, USA: alpha‐cyano‐4‐hydroxycinnamic acid.
Asker M., Krieger J., Liles A., Tinsley I.C., Borner T., Maric I., Doebley S., Furst C.D., Börchers S., Longo F., Bhat Y.R., De Jonghe B.C., Hayes M.R., Doyle R.P, & Skibicka K.P. (2023). Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects. Diabetes, Obesity & Metabolism, 25(3), 856-877.
Publication 2023
1-methyl-2-pyrrolidinone 2,3-dihydroxybenzoic acid acetonitrile Acids alpha-cyano-4-hydroxycinnamic acid Amino Acids Carbodiimides Dimethylformamide Esters Ethyl Ether Methanol N-hydroxysulfosuccimide oxyma Rink amide resin Sulfoxide, Dimethyl Thioacetamide Triazoles triethylamine Vitamin B12
4
Mass Spectrometry Analysis Protocol
All chemicals applied were not subjected
to further purification. Super DHB, 2,5-dihydroxybenzoic acid:2-hydroxy-5-methoxybenzoic
acid (9:1) (sDHB, >99.0%), 2′,4′,6′-trihydroxyacetophenone
monohydrate (THAP, >95.5%), and 5-chloro-2-mercaptobenzothiazole
(CMBZT,
>90.0%) were purchased from Sigma-Aldrich (MO, USA), 9-aminoacradine
(9AA, >98.0%) was purchased from TCI America (OR, USA), 3-hydroxypicolinic
acid (HPA, > 99.9%) was purchased from Chem-Impex International
(IL,
USA), and α-cyano-4-hydroxy-cinnamic acid (CHCA, >99.0%)
was
purchased from Fluka-Honeywell (NC, USA). Methanol and acetonitrile
(Optima LC/MS grade) were purchased from Fisher Scientific (NH, USA).
Peptide Calibration Standard II and MTP 384 Target plate Ground Steel
TF were purchased from Bruker (MA, USA). Lipid standards, 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol)
(sodium salt) (PG 18:1 (Δ9-Cis)), 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (PE (18:1/16:0)), 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt) (PA (18:1/16:0)), and
1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (LPG(18:1)), were purchased from Avanti Polar
Lipids (AL, USA). Quinolone standards, 2-heptyl-3-hydroxy-4(1H)-quinolone (PQS) and 2-heptyl-4-quinolinoal 1-oxide (HQNO),
and lactone standard N-hexanoyl-l-homoserine
lactone (HSL) were purchased from Cayman Chemical Company (MI, USA).
Quinolone standard 2-heptyl-4-quinolone (HHQ), rhamnolipids, 95%(mono–rhamnolipid
dominant), and rhamnolipids, 95% (di–rhamnolipid dominant)
were purchased from Sigma-Aldrich (MO, USA). Luria–Bertani
(LB) broth (Miller) and LB agar (Miller) were purchased from Fisher
BioReagents (PA, USA).
Wamer N.C., Morse C.N., Gadient J.N., Dodson T.A., Carlson E.A, & Prestwich E.G. (2023). Comparison of Small Biomolecule Ionization and Fragmentation in Pseudomonas aeruginosa Using Common MALDI Matrices. Journal of the American Society for Mass Spectrometry, 34(3), 355-365.
Full text: Click here
Publication 2023
1-palmitoyl-2-oleoyl-glycero-3-phosphatidic acid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine 2,3-dihydroxybenzoic acid 5-chloro-2-mercaptobenzothiazole acetonitrile Agar Caimans Glycerin Hydroxy Acids Lactones Lipids Methanol Oxides Peptides Quinolones rhamnolipid SDHB protein, human Sodium Sodium Chloride
5
MALDI-MS Imaging of Spheroid Metabolism
Spheroids treated with different FPOP conditions
were embedded in gelatin and cryosectioned to 12 μm thick and
thaw-mounted to indium tin oxide (ITO) slides. Matrix solution was
prepared by dissolving 2,5-dihydroxybenzoic acid (DHB) (Sigma-Aldrich,
St. Louis, MO) in 50:50 acetonitrile–water with 0.1% formic
acid (FA) at a concentration of 10 mg/mL. Matrix solution was sprayed
onto the slides using a TM sprayer. A 15T Solarix FT-ICR (Bruker Daltonics,
Billerica, MA) was used to detect molecules at an m/z range of 92 to 1000 in positiveion mode. The
laser spot size was set to small with the raster of 50 μm along
both the x and y axes. The images and intensity plots were processed
using SCiLS Lab 2021c (Bruker Daltonics, Billerica, MA). All spectra
were normalized against total ion count, using peak intensity divided
by the sum of all signal intensities in the mass spectra.
Shortt R.L., Wang Y., Hummon A.B, & Jones L.M. (2023). Development of Spheroid-FPOP: An In-Cell Protein Footprinting Method for 3D Tumor Spheroids. Journal of the American Society for Mass Spectrometry, 34(3), 417-425.
Full text: Click here
Publication 2023
2,3-dihydroxybenzoic acid acetonitrile Epistropheus Gelatins indium tin oxide Mass Spectrometry

Top products related to «2,3-dihydroxybenzoic acid»

1
2 5 dihydroxybenzoic acid by Merck Group
Sourced in United States, Germany, United Kingdom, Sao Tome and Principe, China, France
2,5-dihydroxybenzoic acid is a chemical compound that serves as a laboratory reagent. It is a crystalline solid with the molecular formula C7H6O3. This compound can be used in various analytical and research applications.
2
Caffeic acid by Merck Group
Sourced in United States, Germany, Italy, France, Poland, Spain, China, United Kingdom, Australia, Sao Tome and Principe, Switzerland, India, Ireland, Canada, Macao, Brazil, Austria, Mexico, Czechia, Portugal
Caffeic acid is a phenolic compound commonly found in various plants. It serves as a laboratory standard for the identification and quantification of similar phenolic compounds using analytical techniques such as high-performance liquid chromatography (HPLC) and spectrophotometry.
3
2 5 dihydroxybenzoic acid dhb by Merck Group
Sourced in United States, Germany, Poland, Belgium, United Kingdom, France, Switzerland
2,5-dihydroxybenzoic acid (DHB) is a chemical compound that is commonly used as a matrix for matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. It is a crystalline solid with the molecular formula C₇H₆O₃.
4
Gallic acid by Merck Group
Sourced in United States, Germany, Italy, Spain, France, India, China, Poland, Australia, United Kingdom, Sao Tome and Principe, Brazil, Chile, Ireland, Canada, Singapore, Switzerland, Malaysia, Portugal, Mexico, Hungary, New Zealand, Belgium, Czechia, Macao, Hong Kong, Sweden, Argentina, Cameroon, Japan, Slovakia, Serbia
Gallic acid is a naturally occurring organic compound that can be used as a laboratory reagent. It is a white to light tan crystalline solid with the chemical formula C6H2(OH)3COOH. Gallic acid is commonly used in various analytical and research applications.
5
Trifluoroacetic acid by Merck Group
Sourced in United States, Germany, United Kingdom, France, Spain, Italy, Australia, China, India, Sao Tome and Principe, Poland, Canada, Switzerland, Macao, Belgium, Netherlands, Czechia, Japan, Austria, Brazil, Denmark, Ireland
Trifluoroacetic acid is a colorless, corrosive liquid commonly used as a reagent in organic synthesis and analytical chemistry. It has the chemical formula CF3COOH.
6
Ferulic acid by Merck Group
Sourced in United States, Germany, Italy, United Kingdom, Spain, China, France, Poland, Australia, Ireland, Malaysia, Canada, India, Switzerland, Sao Tome and Principe, Japan, Brazil, Denmark
Ferulic acid is a phenolic compound that can be found in various plant sources, including rice, wheat, oats, and vegetables. It is commonly used as a lab equipment product for research and analysis purposes. Ferulic acid has antioxidant properties and can be used in a variety of applications, such as the study of plant-based compounds and their potential health benefits.
7
3 4 dihydroxybenzoic acid by Merck Group
Sourced in United States, Germany, United Kingdom, Spain, Italy
3,4-dihydroxybenzoic acid is a chemical compound that can be used as a laboratory reagent. It has the molecular formula C7H6O4. The compound is a crystalline solid at room temperature.
8
Methanol by Merck Group
Sourced in Germany, United States, Italy, India, United Kingdom, China, France, Poland, Spain, Switzerland, Australia, Canada, Sao Tome and Principe, Brazil, Ireland, Japan, Belgium, Portugal, Singapore, Macao, Malaysia, Czechia, Mexico, Indonesia, Chile, Denmark, Sweden, Bulgaria, Netherlands, Finland, Hungary, Austria, Israel, Norway, Egypt, Argentina, Greece, Kenya, Thailand, Pakistan
Methanol is a clear, colorless, and flammable liquid that is widely used in various industrial and laboratory applications. It serves as a solvent, fuel, and chemical intermediate. Methanol has a simple chemical formula of CH3OH and a boiling point of 64.7°C. It is a versatile compound that is widely used in the production of other chemicals, as well as in the fuel industry.
9
Syringic acid by Merck Group
Sourced in United States, Germany, Italy, United Kingdom, China, Spain, Japan, France, Sao Tome and Principe, Poland, India, Australia
Syringic acid is a phenolic compound that can be used as a chemical reagent in laboratory research and analysis. It serves as a standard reference material for analytical techniques such as chromatography and spectroscopy. The specific core function of syringic acid is to act as a calibration and measurement standard for the quantification of similar phenolic compounds in various samples.
10
P coumaric acid by Merck Group
Sourced in United States, Germany, Italy, Spain, France, China, Poland, United Kingdom, Sao Tome and Principe, Switzerland, Canada, Ireland, India, Australia, Japan, Macao, Portugal
P-coumaric acid is a naturally occurring phenolic compound that can be utilized as a reference standard or an analytical reagent in various laboratory settings. It is a white to off-white crystalline solid that is soluble in organic solvents. P-coumaric acid is commonly used as a standard in analytical techniques, such as high-performance liquid chromatography (HPLC) and spectrophotometric measurements, to quantify and characterize similar compounds in sample matrices.

More about "2,3-dihydroxybenzoic acid"

2,3-Dihydroxybenzoic acid, also known as 2,3-DHB or 2,3-DHBA, is a naturally occurring organic compound derived from benzoic acid.
This phenolic acid is characterized by the presence of two hydroxyl groups attached to the benzene ring at the 2 and 3 positions. 2,3-DHBA has gained attention due to its potential applications in various fields, including pharmaceuticals, materials science, and environmental remediation.
Researchers have been working to optimize the synthesis and utilization of 2,3-DHBA.
Protocols from literature, preprints, and patents can be explored using the AI-driven platform PubCompare.ai, which enhances reproducibility and accuracy through intelligent comparisons to identify the best methodologies and products.
This platform can streamline the research process and leverage the power of AI-enhanced discoverability to unlock new insights and optimize the study of 2,3-dihydroxybenzoic acid.
Other related compounds, such as 2,5-dihydroxybenzoic acid (2,5-DHB), caffeic acid, gallic acid, ferulic acid, and 3,4-dihydroxybenzoic acid, have also been the subject of research optimization efforts.
These compounds share structural similarities and may exhibit overlapping properties and applications.
By exploring the available research on these related compounds, scientists can gain a more comprehensive understanding of the potential of 2,3-DHBA and its analogues.
The study of 2,3-DHBA and its derivatives can be further enriched by considering the insights gained from the investigation of other compounds, such as trifluoroacetic acid, methanol, syringic acid, and p-coumaric acid.
These compounds may provide valuable information about reaction conditions, purification techniques, and analytical methods that can be applied to the optimization of 2,3-DHBA research.
By leveraging the power of AI-driven platforms like PubCompare.ai, researchers can streamline their efforts, enhance reproducibility, and identify the most effective methodologies for studying 2,3-dihydroxybenzoic acid and its related compounds.
This holistic approach can lead to new discoveries and unlock the full potential of these versatile organic compounds.