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4-toluenesulfonic acid

4-Toluenesulfonic acid is a commonly used organic compound with a variety of applications in research and industry.
This sulfonic acid derivative of toluene is known for its ability to act as a catalyst, pH adjuster, and reagent in numerous chemical reactions and processes.
PubCompare.ai's AI-powered platform can help researchers easily locate protocols, preprints, and patents related to 4-toluenesulfonic acid, allowing them to optimize their workflow and make informed decisions.
By leveraging AI-driven comparisons, users can identify the best products and protocols for their specific needs, streamlining their research and experencing the future of scientific inquiry.

Most cited protocols related to «4-toluenesulfonic acid»

Synthesis of 3-Benzylidene-Chroman-4-one

Cited 4 times

To a solution of the chroman-4-one (6c) (71 mg, 0.34 mmol) in benzene (2 mL) was added isovanillin (62 mg, 0.41 mmol) and p-toluenesulfonic acid (7 mg, 0.03 mmol) at 0 °C. The reaction mixture was refluxed for 12 h. After cooling to room temperature, the reaction mixture was concentrated under reduced pressure. The residue was purified by flash column chromatography on silica gel (ethyl acetate : n-hexane = 1 : 1) to afford the 3-benzylidene-chroman-4-one (7c) (72 mg, 62%). ¹H-NMR (600 MHz, CDCl₃) δ 7.72 (s, 1H), 6.89-6.87 (m, 2H), 6.83 (d, 1H, J = 8.4Hz), 6.11 (s, 1H), 6.06 (s, 1H), 5.23 (s, 2H), 3.93 (s, 3H), 3.90 (s, 3H), 3.82 (s, 3H); ¹³C-NMR (150 MHz, CDCl₃) δ 179.5, 165.6, 164.6, 162.7, 147.4, 145.5, 135.7, 130.5, 128.3, 123.0, 115.8, 110.5, 107.3, 9305, 93.5, 67.6, 56.1, 56.0, 55.5; HRMS (EI): mass calcd for C₁₉H₁₈O₆ [M⁺], 342.1103; found, 342.1101.

Basavarajappa H.D., Lee B., Lee H., Sulaiman R.S., An H., Magaña C., Shadmand M., Vayl A., Rajashekhar G., Kim E.Y., Suh Y.G., Lee K., Seo S.Y, & Corson T.W. (2015). Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization. Journal of medicinal chemistry, 58(12), 5015-5027.

Publication 2015

1H NMR 4-toluenesulfonic acid Benzene Carbon-13 Magnetic Resonance Spectroscopy Chromans Chromatography ethyl acetate isovanillin n-hexane Pressure Silica Gel

Synthesis of mPEG-ABCPA-mPEG Macro-initiators

Cited 3 times

mPEG–ABCPA–mPEG
macro-initiators were synthesized through an esterification of mPEG
(molecular weight, 2.0 or 5.0 kDa) and ABCPA, using DCC as a coupling
reagent and 4-(dimethylamino)pyridinium 4-toluenesulfonate (DPTS,
which was made by separately dissolving DMAP and p-toluenesulfonic acid in tetrahydrofuran (THF) and mixing the two
solutions using a 1:1 molar equivalence) as a catalyst (Scheme 1).^{29 (link)} ABCPA (1 equiv), mPEG (2 equiv), and DPTS (0.3 equiv) (or 0.280
g of ABCPA, 10 g of mPEG, 0.094 g of DPTS) were dissolved in 50 mL
of dry dichloromethane (DCM) and put on ice. Next, 3 equiv of DCC
(0.619 g of DCC) were dissolved in 50 mL of DCM and dropwise added
to the mPEG solution under nitrogen atmosphere. After addition of
DCC, the ice bath was removed allowing the reaction mixture to reach
room temperature. After 16 h at room temperature, the reaction mixture
was filtered to remove the precipitated 1,3-dicyclohexyl urea and
the solvent was removed in vacuo. The product was dissolved in water,
stirred for 2 h, and dialyzed against water for 72 h at 4 °C.
The sample was freeze-dried to obtain a fluffy white product.
The product was analyzed by
GPC using a PSS PFG analytical linear
S column and PEGs of narrow molecular weights as calibration standards,
as described previously. Samples were prepared by dissolving approximately
5 mg of the MI in 1 mL of dimethylformamide (DMF) containing 10 mM
LiCl. Samples of 20 μL were injected, the eluent was DMF containing
10 mM LiCl, the elution rate was 0.7 mL/min, the temperature was 40
°C, and detection was done using a refractive index detector.^{30 (link)}The product was further analyzed by ¹H NMR spectroscopy
(20 mg product was dissolved in 700 μL CDCl₃). To
determine the unreacted mPEG-OH content, TAIC was added to the sample
and analyzed again after 20 min using ¹H NMR spectroscopy.
After reaction with TAIC, the signal of the methylene group neighboring
the terminal hydroxyl group shifts from 4.2 to 4.4 ppm and the amount
of unreacted mPEG-OH can subsequently be determined based on the peak
areas.^{31 (link),32 (link)}

Bagheri M., Bresseleers J., Varela-Moreira A., Sandre O., Meeuwissen S.A., Schiffelers R.M., Metselaar J.M., van Nostrum C.F., van Hest J.C, & Hennink W.E. (2018). Effect of Formulation and Processing Parameters on the Size of mPEG-b-p(HPMA-Bz) Polymeric Micelles. Langmuir, 34(50), 15495-15506.

Publication 2018

1H NMR 4-(1-(4-azidobenzamidomethyl)ethenyl)-2-carboxypyrrolidin-3-ylacetic acid 4-toluenesulfonic acid Atmosphere Bath carbene Dimethylformamide diphenylthiosulfinate Esterification Freezing G 619 Hydroxyl Radical Methylene Chloride Molar monomethoxypolyethylene glycol Nitrogen Solvents Spectroscopy, Nuclear Magnetic Resonance Spectrum Analysis tetrahydrofuran Urea

Synthesis and Characterization of PEGylated Polymers

Cited 3 times

4-(Dimethylamino)pyridine
(DMAP), p-toluenesulfonic acid, 4,4-azobis(4-cyanopentanoic
acid)
(ABCPA), dl-1-amino-2-propanol, methacryloyl chloride, benzoyl
chloride, poly(ethylene glycol) methyl ether (mPEG) 2 kDa, N,N′-dicyclohexylcarbodiimide (DCC),
trichloroacetyl isocyanate (TAIC), bovine serum albumin, and pyrene
were obtained from Sigma-Aldrich (Darmstadt, Germany) and used without
further purification. mPEG 5 kDa was obtained from Polysciences (Warrington)
and dried in a vacuum oven overnight at 70 °C. EasiVial PEG standards
for gel permeation chromatography (GPC) analysis were obtained from
Agilent (Santa Clara). All solvents were purchased from commercial
suppliers and used as received.

Publication 2018

4-(1-(4-azidobenzamidomethyl)ethenyl)-2-carboxypyrrolidin-3-ylacetic acid 4-toluenesulfonic acid Dicyclohexylcarbodiimide ethylene glycol diethyl ether Gel Chromatography methacryloyl chloride monomethoxypolyethylene glycol Poly A Propanols pyridine Serum Albumin, Bovine Solvents trichloroacetyl isocyanate Vacuum

Indole-3-propylamine Condensation Synthesis

Cited 3 times

p-Toluenesulfonic acid (0.11 g, 0.57 mmol) was added to a flask charged with 3-(1H-indol-3-yl)-propylamine^{15 (link)} (0.10 g, 0.57 mmol) and 5-chloroisatin (0.12 g, 0.63 mmol) in absolute ethanol (5 mL) and heated to 100 °C. After 15 h, the reaction mixture was cooled to room temperature and concentrated in vacuo. The residue was dissolved in ethyl acetate and washed with 0.5 M NaOH and saturated aqueous NaCl. The organic layer was separated and dried over Na₂SO₄, filtered, and concentrated in vacuo. The residue was purified by flash chromatography to provide 6 as an orange solid (17 mg, 9%). ¹H NMR (300 MHz, DMSO-d₆): δ 10.56 (s, 1H), 10.10 (s, 1H), 7.46 (dd, J = 7.0, 1.5 Hz, 1H), 7.32 (dd, J = 8.4, 2.2 Hz, 1H), 7.15 (m, 2H), 7.00 (dd, J = 6.9, 1.5 Hz, 1H), 6.97 (dd, J = 6.9, 1.8 Hz, 1H), 6.93 (d, J = 8.4 Hz, 1H), 3.47 (m, 2H), 3.02 (m, 3H), 1.98 (m, 2H). MS (ESI) m/z 338.0 (M + H)⁺.

Yeung B.K., Zou B., Rottmann M., Lakshminarayana S.B., Ang S.H., Leong S.Y., Tan J., Wong J., Keller-Maerki S., Fischli C., Goh A., Schmitt E.K., Krastel P., Francotte E., Kuhen K., Plouffe D., Henson K., Wagner T., Winzeler E.A., Petersen F., Brun R., Dartois V., Diagana T.T, & Keller T.H. (2010). Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria. Journal of Medicinal Chemistry, 53(14), 5155-5164.

Publication 2010

1H NMR 4-toluenesulfonic acid Chromatography Ethanol ethyl acetate Sodium Chloride Sulfoxide, Dimethyl Z 338

Synthesis of 3-Benzylidene-Chroman-4-One

Cited 2 times

To a solution of the chroman-4-one (6b) (238 mg, 1.0 mmol) in benzene (25 mL) was added isovanillin (170 mg, 1.1 mmol) and p-toluenesulfonic acid (20 mg, 0.1 mmol) at 0 °C. The reaction mixture was refluxed for 12 h. After cooling to room temperature, the reaction mixture was concentrated under reduced pressure. The residue was purified by flash column chromatography on silica gel (ethyl acetate / n-hexane = 1 : 1) to afford the 3-benzylidene-chroman-4-one (7b) (215 mg, 58%). ¹H-NMR (600 MHz, CDCl₃) δ 7.74 (s, 1H), 6.91-6.84 (m, 3H), 6.26 (s, 1H), 5.67 (s, 1H), 5.24 (d, 2H, J = 1.8 Hz); 3.98 (s, 3H), 3.94 (s, 3H), 3.88 (s, 3H), 3.83 (s, 3H); ¹³C-NMR (150 MHz, CDCl₃) δ 179.5, 159.3, 159.1, 154.7, 147.5, 145.5, 137.8, 136.2, 130.1, 128.1, 123.2, 115.7, 110.5, 96.1, 67.6, 61.6, 61.3, 60.3, 60.3, 56.0, 55.9; HRMS (EI): mass calcd for C₂₀H₂₀O₇ [M⁺], 372.1209; found, 372.1208.

Publication 2015

1H NMR 4-toluenesulfonic acid Benzene Carbon-13 Magnetic Resonance Spectroscopy Chromans Chromatography ethyl acetate isovanillin n-hexane Pressure Silica Gel

Most recents protocols related to «4-toluenesulfonic acid»

Brønsted Acidic Carbon Materials Synthesis

Brønsted acidic carbon materials were synthesized by one-step hydrothermal carbonization using the procedure reported by Xiao and coworkers with a little modification.⁵⁸ The mixture of the d-glucose (10 g), citric acid monohydrate (4 g, 20 mmol), Brønsted acid (p-toluenesulfonic acid (TsOH), sulfuric acid (H₂SO₄) or hydrochloric acid (HCl), 10 mmol), and 80 mL distilled water was charged in a 100 mL Teflon-lined stainless-steel autoclave. The mixture was heated at 180 °C for 4 h in an oven. Black carbonaceous materials were obtained by filtration and washed several times with distilled water and followed by methanol, and then dried at 80 °C for 6 h. Three samples were prepared through this procedure including C–TsOH, C–H₂SO_4, and C–HCl, which had synthesized yields per 100 g of d-glucose of 36.3, 38.1, and 34.5 wt%, respectively.

Nguyen T.H., Phan H.B., Nguyen T.H., Tran K.N., Nguyen L.H., Doan T.L, & Tran P.H. (2023). Conversion of cellulose into valuable chemicals using sulfonated amorphous carbon in 1-ethyl-3-methylimidazolium chloride. RSC Advances, 13(11), 7257-7266.

Publication 2023

4-toluenesulfonic acid Acids Carbon Citric Acid Monohydrate Filtration Glucose Hydrochloric acid Methanol Stainless Steel Sulfuric Acids Teflon

Comprehensive Biomass Conversion Protocol

d-Glucose monohydrate (>99%), cellulose (>99%), HMF (>99%), DFF (>99%), FA (>99), LA (>99%), Fur (>99%), FDCA (>99%), choline chloride (>99%), citric acid monohydrate (>99%), oxalic acid dihydrate (>99%), malonic acid (>99%), fumaric acid (>99%), adipic acid (>99%), [EMIM]Cl (98%), p-toluenesulfonic acid (>99%), sulfuric acid (98%), hydrochloric acid (36%), THF (>99%) were obtained from Sigma-Aldrich. All chemical substances were used without any further purification.

Publication 2023

4-toluenesulfonic acid Adipic Acids Cellulose Choline Chloride Citric Acid Monohydrate fumaric acid Hydrochloric acid malonic acid Monohydrate, Glucose Oxalic Acids Sulfuric Acids

Biomass Pretreatment and Conversion

All reagents were analytically pure and were used immediately upon receipt. Glucose (99%), xylose (99%), tetrahydrofuran (99%), pyridine (99%), glutaraldehyde (50%), epichlorohydrin (98%), hexanediamine (99%), diphenylmethane diisocyanate (98%), and p-toluenesulfonic acid (99%) were purchased from Innochem (Shanghai, China). Dichloromethane (99%), lithium bromide (99%), furfural (99%), and phosphoric acid (75 wt%~80 wt%) were purchased from Aladdin^® Chemicals (Shanghai, China); hydrochloric acid (37 wt%), acetone (99%), and ethanol (99%) were purchased from China National Pharmaceutical Group Corporation (Beijing, China). 5-hydroxymethylfurfural (HMF) was purchased from Bidepharm (Shanghai, China). Eucalyptus and masson pine (40–80 mesh) were provided by Qingshan Paper Co., Ltd. (Sanming, China), and the straw (40–80 mesh) was obtained from the State Key Laboratory of Bio-based Materials and Green Paper of Qilu University of Technology (Jinan, China).

Huang L., Sun W., Shuai L., Luo X, & Liu J. (2023). Lignocelluloses-Based Furan-Acetone Adducts as Wood Adhesives for Plywood Production. Polymers, 15(4), 996.

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Publication 2023

4,4'-diphenylmethane diisocyanate 4-toluenesulfonic acid 5-hydroxymethylfurfural Acetone Epichlorohydrin Ethanol Eucalyptus Furaldehyde Glucose Glutaral Hydrochloric acid lithium bromide Methylene Chloride Pharmaceutical Preparations Phosphoric Acids Pinus pyridine tetrahydrofuran Xylose

Preparation of Adhesive-Bonded Poplar Plywood

Preparation of adhesive: Initially, the adducts were vacuum dried at 50 °C for 24 h and then ground into a powder with a quartz mortar. About 10–20 g of the adducts was weighed with the addition of acetone (about 50% mass of the adduct) for dissolving the adduct. The mixture was stirred evenly to form a gel. Next, hydrochloric acid (HCl), phosphoric acid (PA), or p-toluenesulfonic acid (p-TsOH) was added as a curing agent, and the loading of the curing agent was about 2–15% of the mass of the adduct. Hexamethylene diamine (EDA), glutaraldehyde (GA), epichlorohydrin (ECH), or diphenylmethane diisocyanate (MDI) was added as cross-linking agents during the preparation process, and the amount of the added cross-linking agent was about 3–9% of the adhesive mass. After the addition of all additives, the mixture was fully stirred and then coated on the surface of the veneers.
Preparation of three-layer poplar plywood: The poplar veneer was cut into several sheets with a size of 100 mm × 300 mm × 1.6 mm, and the moisture content of the veneers were between 8% and 15%. The grain of each layer was perpendicularly oriented with its adjacent layer. The adhesives were evenly coated on the two sides of the middle-layer veneer (Figure 2) by a rubber brush with a glue sizing of 270 g/m². Prior to hot-pressing, the coated wood veneers were placed in an oven and treated at 80 °C for 8 h to remove excess acetone and prevent glue penetration. Then the three-layer poplar plywood was pressed by a laboratory-scale hot-presser (KS100H, Kesheng Industrial, Dongguan, China) at 120–200 °C for 5–20 min.

Huang L., Sun W., Shuai L., Luo X, & Liu J. (2023). Lignocelluloses-Based Furan-Acetone Adducts as Wood Adhesives for Plywood Production. Polymers, 15(4), 996.

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Publication 2023

4,4'-diphenylmethane diisocyanate 4-toluenesulfonic acid Acetone Cereals Cyclohexane Diamines Epichlorohydrin Glutaral Hydrochloric acid phosphoric acid Populus Powder Quartz Rubber Vacuum

Synthesizing Functional Polymeric Materials

All reagents used in this study were purchased from Sigma-Aldrich (Saint Quentin Fallavier, France) unless otherwise noted. 2,2-bis(hydroxymethyl)propionic acid (bis-MPA, 98%), p-toluenesulfonic acid monohydrate (PTSA.H₂O, >98.5%), 4-(dimethylamino)pyridine (DMAP, 99%), Dowex^®50WX8 hydrogen form (50–100 mesh), ethyl chloroformate (97%), 8-diazabicyclo[5.4.0]undec-7-ene (DBU, 98%), benzoic acid (99.5%), acetone (99.9%), dichloromethane (DCM, 99.5%), tetrahydrofuran (THF, 99.9%), diethyl ether (99%), methanol (CH₃OH, 99.8%), water (HPLC grade), N,N-dimethyl formamide (DMF, 99.9%), diethyl (3-bromopropyl)phosphonate (95%), copper(I) bromide (CuBr, 98%), N,N,N′,N″,N″-pentamethyldiethylenetriamine (PMDETA, 99%), sodium azide (NaN₃, 99%), and dimethyl (2-hydroxyethyl)phosphonate (95%) were purchased from Acros Organics (Geel, Belgium). 2,2-dimethoxypropane (>98%), N,N’-dicyclohexyldicarbodiimide (DCC, >98%), and triethylamine (TEA, >99%) were purchased from TCI (Zwijndrecht, Belgium). Benzyl alcohol (BnOH, 99%, Alfa Aesar, Karlsruhe, Germany) and dialysis membrane (Standard RC, 3500 Da, Spectrum Laboratories, Racho Dominguez, CA, USA) were used as received. 1-(3,5-bis(trifluoromethyl)phenyl)-3-cyclohexylthiourea (TU) and 5-methyl-5-propargylxycarbonyl-1,3-dioxane-2-one (MPC) were synthesized according to the literature procedures [19 (link),20 (link),21 (link)].

Ho H.T., Nguyen N.H., Rollet M., Phan T.N, & Gigmes D. (2023). Phosphonate-Functionalized Polycarbonates Synthesis through Ring-Opening Polymerization and Alternative Approaches. Polymers, 15(4), 955.

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Publication 2023

1,3,6,8-pyrene tetrasulfonate 4-toluenesulfonic acid Acetone Benzoic Acid Benzyl Alcohol Bromides Copper Dialysis Dimethylformamide dioxane Dowex ethyl chloroformate Ethyl Ether High-Performance Liquid Chromatographies Hydrogen Methanol Methylene Chloride Phosphonates propionic acid pyridine Sodium Azide tetrahydrofuran Tissue, Membrane triethylamine

Top products related to «4-toluenesulfonic acid»

P toluenesulfonic acid by Merck Group

Sourced in United States, Germany, Italy, United Kingdom

P-toluenesulfonic acid is a crystalline organic compound that serves as a common laboratory reagent. It is a white, crystalline solid that is soluble in water and other polar solvents. Its primary function is as an acid catalyst in various chemical reactions and processes.

P toluenesulfonic acid monohydrate by Merck Group

Sourced in United States, Germany

P-toluenesulfonic acid monohydrate is a chemical compound used in various laboratory applications. It is a white crystalline solid with the chemical formula CH3C6H4SO3H·H2O. The compound serves as a catalyst, pH adjuster, and reagent in chemical synthesis and analysis procedures.

P toluenesulfonic acid by Thermo Fisher Scientific

Sourced in United Kingdom, United States

P-toluenesulfonic acid is a chemical compound that is commonly used as a catalyst in various chemical reactions. It is a white crystalline solid with a mild aromatic odor. The compound is soluble in water, alcohols, and other organic solvents.

Toluene by Merck Group

Sourced in United States, Germany, Italy, United Kingdom, India, Spain, Japan, Poland, France, Switzerland, Belgium, Canada, Portugal, China, Sweden, Singapore, Indonesia, Australia, Mexico, Brazil, Czechia

Toluene is a colorless, flammable liquid with a distinctive aromatic odor. It is a common organic solvent used in various industrial and laboratory applications. Toluene has a chemical formula of C6H5CH3 and is derived from the distillation of petroleum.

Methanol by Merck Group

Sourced in Germany, United States, Italy, India, United Kingdom, China, France, Poland, Spain, Switzerland, Australia, Canada, Sao Tome and Principe, Brazil, Ireland, Japan, Belgium, Portugal, Singapore, Macao, Malaysia, Czechia, Mexico, Indonesia, Chile, Denmark, Sweden, Bulgaria, Netherlands, Finland, Hungary, Austria, Israel, Norway, Egypt, Argentina, Greece, Kenya, Thailand, Pakistan

Methanol is a clear, colorless, and flammable liquid that is widely used in various industrial and laboratory applications. It serves as a solvent, fuel, and chemical intermediate. Methanol has a simple chemical formula of CH3OH and a boiling point of 64.7°C. It is a versatile compound that is widely used in the production of other chemicals, as well as in the fuel industry.

P toluenesulfonic acid by Sinopharm

Sourced in China

P-toluenesulfonic acid is a chemical compound that serves as a key laboratory reagent. It functions as a catalyst, proton donor, and drying agent in various chemical processes and reactions.

Dimethyl sulfoxide (dmso) by Merck Group

Sourced in United States, Germany, United Kingdom, China, Italy, Sao Tome and Principe, France, Macao, India, Canada, Switzerland, Japan, Australia, Spain, Poland, Belgium, Brazil, Czechia, Portugal, Austria, Denmark, Israel, Sweden, Ireland, Hungary, Mexico, Netherlands, Singapore, Indonesia, Slovakia, Cameroon, Norway, Thailand, Chile, Finland, Malaysia, Latvia, New Zealand, Hong Kong, Pakistan, Uruguay, Bangladesh

DMSO is a versatile organic solvent commonly used in laboratory settings. It has a high boiling point, low viscosity, and the ability to dissolve a wide range of polar and non-polar compounds. DMSO's core function is as a solvent, allowing for the effective dissolution and handling of various chemical substances during research and experimentation.

Ethanol by Merck Group

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Ethanol is a clear, colorless liquid chemical compound commonly used in laboratory settings. It is a key component in various scientific applications, serving as a solvent, disinfectant, and fuel source. Ethanol has a molecular formula of C2H6O and a range of industrial and research uses.

N n dimethylformamide (dmf) by Merck Group

Sourced in United States, Germany, United Kingdom, China, Italy, Canada, India, Australia, Japan, Spain, Singapore, Sao Tome and Principe, Poland, France, Switzerland, Macao, Chile, Belgium, Czechia, Hungary, Netherlands

N,N-dimethylformamide is a clear, colorless liquid organic compound with the chemical formula (CH3)2NC(O)H. It is a common laboratory solvent used in various chemical reactions and processes.

Dichloromethane by Merck Group

Sourced in Germany, United States, United Kingdom, Italy, India, France, Spain, China, Australia, Poland, Sweden, Sao Tome and Principe, Switzerland, Belgium, Denmark, Canada, Macao, Brazil, Portugal, Pakistan, Singapore, Ireland, Czechia, Mexico

Dichloromethane is a clear, colorless, and volatile liquid commonly used as a laboratory solvent. It has a molecular formula of CH2Cl2 and a molar mass of 84.93 g/mol. Dichloromethane is known for its high solvent power and low boiling point, making it suitable for various laboratory applications where a versatile and efficient solvent is required.

What are the common uses and applications of 4-toluenesulfonic acid?

4-Toluenesulfonic acid is a versatile organic compound with a wide range of applications in research and industry. It is commonly used as a catalyst, pH adjuster, and reagent in various chemical reactions and processes. The sulfonic acid group gives 4-toluenesulfonic acid unique properties that make it useful for applications such as organic synthesis, polymer chemistry, and analytical methods.

How can I find the best protocols and products related to 4-toluenesulfonic acid for my research?

PubCompare.ai's AI-powered platform can help you streamline your research on 4-toluenesulfonic acid. The platform allows you to efficiently screen protocol literature, leveraging AI to pinpoint critical insights. PubCompare.ai's AI-driven analysis can help you identify the most effective protocols related to 4-toluenesulfonic acid for your specific research goals, enabling you to choose the best option for reproducibility and accuracy. With PubCompare.ai, you can make informed decisions and optimize your workflow when working with this versatile organic compound.

Are there different variations or types of 4-toluenesulfonic acid I should be aware of?

Yes, there are several variations of 4-toluenesulfonic acid that you may encounter. The most common forms include the anhydrous powder, aqueous solutions, and hydrated crystals. Each form may have slightly different properties and applications, so it's important to carefully select the appropriate version for your specific needs. PubCompare.ai's platform can help you compare the different product options and choose the best one for your research.

What are some common challenges or considerations when working with 4-toluenesulfonic acid?

When working with 4-toluenesulfonic acid, it's important to be mindful of its corrosive nature and to handle it with appropriate safety precautions. The sulfonic acid group can be irritating to the skin and eyes, so proper personal protective equipment (PPE) is essential. Additionally, 4-toluenesulfonic acid is hygroscopic, meaning it can readily absorb moisture from the air, which can affect its purity and reactivity. Proper storage and handling techniques are crucial to ensure the reliability and reproducibility of your experiments. PubCompare.ai's platform can provide guidance on best practices and help you identify the most suitable protocols and products for your research needs.

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4-toluenesulfonic acid, p-toluenesulfonic acid, tosylic acid, p-TSA, toluene, methanol, DMSO, ethanol, N,N-dimethylformamide, dichloromethane, catalyst, pH adjuster, reagent, chemical reactions, protocols, preprints, patents, research, industry, AI-powered comparisons, workflow optimization, scientific inquiry