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Articaine

Articaine is a local anesthetic commonly used in dentistry and oral surgery.
It is a potent amide-type anesthetic that provides rapid onset and long-lasting numbing effects.
PubCompare.ai helps researchers optimize their Articaine research by using AI-driven protocol comparisons to locate the best reproducible and accurate Articaine protocols from literature, pre-prrnts, and patents.
This tool enhances research by offering intelligent analysis and comparison tools to support Articaine-related studies.

Most cited protocols related to «Articaine»

The surgical preparation included dental polishing 10 days before, 2 g of amoxicillin 1 h before, and 1 min preceding the beginning of the sinus lift procedure mouthwash with chlorhexidine 0.2%.
All surgeries were performed by the same surgeon, preceded by local anaesthesia (Articaine 4 mg/mL + 0.01 mg/L Artinibsa™, Barcelona, Spain), followed by an incision on the maxillary crest, with two accessory vertical incisions. The detachment and elevation of the flap were performed in total thickness exposing the lateral bone wall of the maxillary sinus [10 (link)].
A lateral oval shape osteotomy was performed with a piezoelectric instrument (NSK VarioSurg™, Tokyo, Japan) or with a spherical diamond tip (NSK™, Tokyo, Japan). The Schneider’s membrane was carefully lifted through proper curettes (Hu-Friedy®, Chicago, IL, USA). Following the Schneider’s membrane elevation, a randomised opaque sealed sterilized envelope containing the assignment code was opened: (1). test with a cortico-medullar porcine xenograft Osteobiol Mp3® (Tecnoss™, Torino, Italy, granulometry between 600–1000 µm with 10% collagen of type I and III) [29 (link),30 (link)]; and (2). control with harvest of intraoral autologous bone graft.
Autologous bone was collected from mandible body or mental symphysis and particulate with a bone mill (ACE™, Pearl St. Brockton, MA, USA). Sinus cavities were filled up to the desired height. The lateral osteotomy was then covered with a collagen membrane (Osteobiol by Tecnoss™, Torino, Italy) and the flaps were sutured with polyamide 4.0 (Supramida™, B Braun, Melsungen, Germany).
The postoperative protocol comprised: Amoxicillin 1 g for a week; chlorhexidine gel 0.2% for 2 weeks; Ibuprofen 400 mg, if pain; soft diet for 2 weeks; ice application within the first 48 h. Additionally, the patients should avoid blowing their noses and using straws; sneezing with their mouth opened; and using any superior removable prosthesis. The sutures were removed after 10 days.
Six months after surgical intervention, a new computer tomography (CT) was made, patients were inquired about treatment preferences and the second surgical stage was performed by the same surgeon under local anaesthesia administration, while the incision and the elevation of the flap were performed in total thickness. The bone collection was performed on both regenerated sides before the use of the first drill of the implant system. The procedure was carried on trans alveolar in the implant sites, with a trephine with an internal diameter of 2 mm and a total diameter of 3 mm (Hager & Meisinger™, Neuss, Germany). Samples were immediately immersed in flasks containing buffered formaldehyde. After bone sample collection, submerged dental implants (Osseo Speed TX™, Astra Tech™, Mölndal, Sweden) were placed following the manufacturer’s recommendations. The flaps were sutured with polyamide 4.0 suture (Supramida™, B Braun™, Melsungen, Germany). After ten days, the sutures were removed, and eventual postoperative complications were clinically evaluated and registered.
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Publication 2021
Amoxicillin Articaine Bones Bone Transplantation Chlorhexidine Collagen Collagen Type I Crista Ampullaris Dental Caries Diamond Diet Drill Formaldehyde Heterografts Human Body Ibuprofen Implant, Dental Limb Prosthesis Local Anesthesia Mandible Maxilla Medulla Oblongata Mouthwashes Nose Nylons Operative Surgical Procedures Oral Cavity osteobiol Osteotomy Pain Patients Pigs Postoperative Complications Respiratory Diaphragm Sinuses, Nasal Specimen Collection Surgeons Surgical Flaps Sutures Tissue, Membrane Tomography Transverse Sinuses
A total of 90 patients with an impacted lower third molar that required surgical removal for the first time were selected. The patients chosen for the study were healthy (ASA I) or had mild systemic disease without functional limitation (ASA II). All patients underwent surgical extraction of impacted lower third molar. Patients excluded from the study were those who could not attend the scheduled appointments, had a limited intelligence quotient, some psychological disorder or mental condition and had difficulties in language comprehension. The exclusion criteria ensured that only the patients that had no difficulties in understanding and following through with the study were selected.
The study was designed according to CONSORT guidelines for randomized clinical trials and was approved by the Research Ethics Committee (CEIC) of the Dental Clinic of the University of Barcelona, Spain (8 (link)). All patients were treated in the Hospital Odontològic de Bellvitge, University of Barcelona, Spain. The incorporation of each subject in the study was decided before knowing the assigned group. Patients were randomly assigned to one of the following three study groups (sequence generated by www.randomization.com).
• Verbal: postoperative instructions were given verbally together with a prescription sheet of the postoperative medication.
• Written: the usual postoperative instructions were given verbally and written, as well as the postoperative medication.
• Additional information: instructions and postoperative medication were given both verbally and written, and additional written information about the postoperative period was also provided ( Table 1, Table 2).
Postoperative information provided to written and additional information groups after the surgical extraction of third molars. Information provided to the group of additional information only. Patients were interviewed about their adherence to the instructions one week after the surgery, at the time of suture removal. They were requested about the compliment of the instructions given, number of days that medication and recommendations were followed and the reason of abandon ( Table 3).
Questionnaire to assess the compliance of postoperative instructions following the surgical extraction of impacted lower third molars. Before surgery, patients completed the Corah Dental Anxiety Scale (9 (link)) and data about age, gender and educational level (Basic, High School / Vocational Training, University) was also collected. Postoperative instructions were given by one resident previously instructed to provide similar instructions according to the study group to which the patient belonged. All surgical interventions were carried out by second year residents of the Master of Oral Surgery and Implantology (Barcelona University) with a similar surgical technique. Patients did not receive any financial compensation for their participation in the study.
The extraction of the impacted lower third molars was performed under local anaesthesia with articaine 4% and epinephrine 1:100.000 (Artinibsa, Inibsa, Lliça de Vall, Spain). The surgical area and all materials were steriles. The surgeon lifted a full-thickness flap that was protected by a cheek retractor. Lingual flap retraction with a Freer periostotom was performed only when deemed necessary by the surgeon. A sterile hand piece at low speed (20,000 rpm) and irrigation with sterile distilled water was used to do the ostectomy and the dental sectioning of the third molar, if needed. The wound was sutured with silk 3-0 (Silkam®, Braun, Tuttlingen, Germany). The surgical technique was similar to that described by Leonard (10 (link)). The following postoperative medication was prescribed.
• Antibiotic (750 mg Amoxicilin. Clamoxyl® -GlaxoSmithKline, Madrid, Spain) orally one tablet every 8 hours for 7 days).
• A NSAID (600mg Ibuprofeno. Espidifen® - Zambon, Barcelona, Spain) orally every 8 hours for 5 days).
• An analgesic (575 mg Metamizol. Nolotil® (Boehringer Ingelheim, Barcelona, Spain) orally, every 8 hours as relief medication).
• Mouthwash (Chlorhexidine Lacer® to 0.12 % (Lacer, Barcelona, Spain), the mouthwash twice daily for 15 days).
All surgeons involved in the study were blinded for which group each patient belonged. Statistical analysis was done using SPSS 15.0 for Windows (SPSS v15.0, SPSS Inc. Chicago, USA, licensed from the University of Barcelona). Demographic data was analysed using Chi-square test and ANOVA test. Chi-square test was used to compare the compliance according to preoperative anxiety level, sociocultural level and how the postoperative instructions were provided. The significance level was set at p <0.05.
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Publication 2014
Analgesics Anti-Inflammatory Agents, Non-Steroidal Antibiotics Anxiety Articaine Cheek Chlorhexidine Dental Anxiety Dental Health Services Dipyrone Epinephrine Ethics Committees, Research Gender Glossoptosis Ibuprofen Local Anesthesia Mental Disorders Mouthwashes neuro-oncological ventral antigen 2, human Nolotil Operative Surgical Procedures Oral Surgical Procedures Patients Penamox Pharmaceutical Preparations Prescription Drugs Silk Sterility, Reproductive Surgeons Surgical Flaps Tablet Third Molars Wounds
The surgical approach was described in detail elsewhere [13 (link)]. Briefly, in both groups’ local anesthesia (4% articaine-hidrocloride with 0.0001% epinephrine - Ultracain DS Forte, Sanofi-Aventis, Paris, France), a midcrestal incision was placed on the keratinized mucosa with no. 15 blades (Aesculap, Braun AG, Tuttlingen, Germany). The midcrestal incision was continued intracrevicularly at the two adjacent teeth mesially and distally both buccally and orally with no. 15C blades. In case of posterior edentulism, the midcrestal incision line length was two-thirds of the entire surgical area, and one-third length was continued mesially to the neighboring two teeth. No vertical-releasing incisions were performed. A full-thickness buccal flap was reflected with elevators up to the MJ, followed by split-thickness mucosal flap preparation over the mucogingival line (MJ). Subsequently, the underlying periosteal layer was elevated from the bone surface. In the simultaneous group, 3.3-mm or 4.1-mm diameter bone level implants (Straumann AG, Basel, Switzerland) were placed in a prosthetically predefined position using surgical guides. No implants with 3.3-mm diameter were placed in molar positions. All implants were positioned supracrestally according to their preplanned prosthetic positions. A single-use disposable bone scraper (Safescraper, Osteogenics Biomedical, Lubbock, TX, USA) was used to harvest AP from the lateral surface of the adjacent alveolar ridge. Bone chips were mixed with BDX (Bio-Oss, Geistlich AG, Wolhusen, Switzerland) in a 1:1 ratio. The 1:1 mixture of AP + BDX was placed laterally and supracrestally to the alveolar ridge. A non-resorbable high-density PTFE (d-PTFE) membrane (Cytoplast, Osteogenics Biomedical, Lubbock, USA) was fixed with titanium pins (Frios Membrane Tacks, Dentsply, York, USA). Double-layer suturing was performed using 4-0 horizontal mattress sutures (Supramid, Braun AG, Tuttlingen, Germany) in order to cover the membrane with the periosteal layer, while 5-0 horizontal mattress and non-interrupted sutures (Supramid, Braun AG, Tuttlingen, Germany) were utilized to close the mucosal layer and to reach a tension-free wound closure. Sutures were removed after 14 days.
In the staged group, at 9 months, a split-thickness flap was elevated in the same way as described above. The titanium pins and the d-PTFE membrane were removed, and 3.3-mm or 4.1-mm diameter bone level implants (Straumann AG, Basel, Switzerland) were placed in a prosthetically predefined position using a surgical template (Fig. 1a–p). Also, in this group, no implants with 3.3-mm diameter were placed in molar positions. The flap was closed with horizontal mattress sutures and single interrupted sutures. Soft tissue augmentation was performed at the time of implant placement if the vertical dimension of the soft tissue thickness was less than 2 mm over the inserted implants. Two months later, in cases where less than 3-mm width of keratinized mucosa was present, palatal epithelialized free gingival grafts were harvested and placed. After another 2 months, implant uncovery was performed.

Case presentation of patient no. 11, (case no. 13 - left mandible) from the staged group. a Baseline CBCT scan, parasagittal section: 2 months after tooth extraction, horizontovertical alveolar defect. b Baseline CBCT scan, frontal section: 2 months after tooth extraction, horizontovertical alveolar defect. c Clinical view of edentulous mandible. d Split-thickness flap preparation. e Bovine-derived xenograft (Geistlich Bio-Oss) and particulate autogenous bone graft. f Adaptation of non-resorbable membrane (Osteogenics Cytoplast) over the composite graft. g Membrane fixation using titanium pins. h Double-layer suturing: tension-free periosteal layer closure with horizontal mattress sutures. i Mucosal layer closure with horizontal mattress and non-interrupted sutures. j Wound healing 2 weeks after surgery. k Postoperative CBCT scan: 9 months after GBR parasagittal section: vertical bone gain. l Postoperative CBCT scan: 9 months after GBR, frontal section: vertical and horizontal bone gain. m Membrane removal at 9 months reentry. n Optimal amount of hard tissue for implant placement. o Guided implant placement (Straumann bone level). p Prosthetically driven implant positioning

In the simultaneous group, membranes and titanium pins were removed at 9 months after the first surgery, and the implants were only uncovered if an adequate peri-implant soft tissue width (i.e., at least 3 mm) surrounding the implants was present (Fig. 2 a–n). Soft tissue augmentation was performed at the time of membrane removal if the peri-implant soft tissue thickness (vertical dimension) was less than 2 mm. The above described reconstruction of keratinized tissues was performed 2 months before the second-stage surgery only in cases without an adequate width and thickness or absence of keratinized tissue.

Case presentation of patient no. 4 (case no. 5 - right mandible) from the simultaneous group. a Baseline CBCT scan, parasagittal section: horizontovertical alveolar defect. b Baseline CBCT scan, frontal section: horizontovertical alveolar defect. c Clinical view of edentulous mandible. d Split-thickness flap preparation. e Guided implant placement, supracrestally positioned implant (Straumann bone level). f Adaptation of non-resorbable membrane (Osteogenics Cytoplast) over the composite graft. g Membrane fixation using titanium pins. h Double-layer suturing. i Postoperative intraoral X-ray. j Healed alveolar ridge 9 months after simultaneous GBR. k Membrane removal at 9 months reentry. l, m, n Optimal amount of hard tissue; previously placed distal implant is covered with hard tissue, additional implant placed mesially

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Publication 2020
Acclimatization Articaine Autografts Bio-Oss Bones Bone Tissue Bos taurus Dentsply DNA Chips Epinephrine Gingiva Grafts Heterografts Local Anesthesia Mandible Molar Mucous Membrane Operative Surgical Procedures Patients Periosteum Polytetrafluoroethylene Radionuclide Imaging Reconstructive Surgical Procedures Ridge, Alveolar Supramid Surgical Flaps Tissue, Membrane Tissues Titanium Tooth Tooth Extraction Wounds X-Rays, Diagnostic
This controlled, randomized, prospective, and split-mouth study was performed at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry at Mahidol University in Bangkok, Thailand. Approval for the protocol of this study was granted by the Committee in the Ethics of Research in Human Dentistry and Pharmacy of Mahidol University, Institutional Review Board (Protocol No. MU-DT/PY-IRB 2015/021.0206).
Twenty-three patients meeting the eligibility criteria listed in Table 1 were enrolled in this study, and informed consent was obtained from each individual.
The patients had similar bilateral lower third molars, and we randomly divided them into two groups as follows:

In the study group, 1.7 ml of 4% lidocaine with 1:100,000 epinephrine was injected through the pterygomandibular space for the IAN block in the impacted lower third molar surgery.

In the comparative group, 1.7 ml of 4% articaine with 1:100,000 epinephrine was injected through the pterygomandibular space for the IAN block in the impacted lower third molar surgery.

The IAN block injections were performed by the same dentist on both sides, and the same surgeon operated on the impacted lower third molars.
Publication 2017
Articaine Dentist Eligibility Determination Epinephrine Faculty Homo sapiens Lidocaine Operative Surgical Procedures Oral Cavity Patients Surgeons Third Molars
A controlled randomized, prospective, split-mouth study was done at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, and approved by The Mahidol University Institutional Review Board (MU-IRB), with COA No. MU-DT/PY-IRB 2016/021.2303. This study involved 62 lower third molar operations in 31 patients, performed under local anesthesia (Table 1 and Fig. 1). The difficulty of lower third molar surgery was evaluated according to the Pell-Gregory classification [20 ].
The patients had similarly bilateral lower third molar, so we randomly divided each side into two groups. Thus, the study group received 8 mg of dexamethasone (4 mg/ml in 2 ml), injected preoperatively through the pterygomandibular space after local anesthesia, whereas the control group received 2 ml of normal saline, also injected preoperatively through the pterygomandibular space after local anesthesia.
Of the 31 patients who participated in this study, 11 were male (22 operations: 35.48%), 20 were female (40 operations: 64.51%) with mean age 22 (age range 16 to 32) years. The patients were blinded to the use of dexamethasone, and all procedures were performed by the same surgeon.
The standard surgical technique of lower third molars surgery was done under local anesthesia with 4% articaine hydrochloride with 1:100,000 epinephrine for inferior alveolar nerve block and long buccal nerve block. All the patients received amoxicillin (500 mg) at intervals of 8 hours for 7 days, and acetaminophen (500 mg) for pain every 6 hours as needed.
Publication 2016
Acetaminophen Amoxicillin Articaine Cardiac Arrest Cheek Dexamethasone Epinephrine Faculty Inferior Alveolar Nerves Local Anesthesia Males Nerve Block Normal Saline Operative Surgical Procedures Oral Cavity Pain Patients Surgeons Third Molars Woman

Most recents protocols related to «Articaine»

The surgical intervention was performed by a dentist with experience in oral surgery and implantology at Hospital da Luz Coimbra (Coimbra, Portugal). After CT and X-ray examination, the patient was anesthetized with Artinibsa (articaine + epinephrine at a dosage of 72 mg/1.8 mL + 0.009 mg/1.8 mL, Inibsa Laboratories, Barcelona, Spain). The indicated tooth was extracted, and alveolar curettage was performed for complete removal of injured tissue and tooth remains. DEXGEL Bone was applied using a syringe and sculpted with a spatula, filling the alveolar socket without exceeding alveolar crest. BL® was mixed with autologous blood previously extracted from the alveolar defect and applied with a spatula. Gum tissue was then sutured to end the process. Volunteers were prescribed with ibuprofen 600 mg (Brufen 600, Mylan, Lda., Lisboa, Portugal) from 12 to 12 h for 3 days and amoxicillin 1 g (Cipamox, Laboratórios Vitória, Amadora, Portugal) from 12 to 12 h for 8 days. In case of allergy, azithromycin 500 mg (Zithromax, Pfizer, NY, USA) was prescribed once daily for 3 days.
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Publication 2023
Allergic Reaction Amoxicillin Articaine Azithromycin BLOOD Bones Brufen Curettage Dentist Epinephrine Gomphosis Ibuprofen Operative Surgical Procedures Oral Surgical Procedures Patients Radiography Ridge, Alveolar Syringes Tissues Tooth Voluntary Workers Zithromax
Implant placements were performed by two residents of oral surgery under the supervision of two experienced specialists in oral surgery and prosthodontics. The MDI dimensions (10, 12, or 14 mm long and 2.0 or 2.5 mm wide; Dentium, Seoul, South Korea) were chosen after measurement of the available bone on CBCT scans. The flapless surgery was performed using the calibrated burs, a physiodispenser (W&H Implantmed, GmbH, Austria), and a saline solution for external drill cooling under local anesthesia (4% articaine or 3% mepivapacaine, 3M, Germany). The bone was prepared to a depth of one-half or two-thirds of implant length depending on the bone density (D3 or D2). The diameter of the drill for bone preparation was smaller than the width of the implant by 0.3–0.7 mm. The self-tapping insertion technique was used, first by a thumb wrench and finally the torque wrench. One MDI was inserted on each side of the edentulous ridge (two MDIs per a patient) in previous sites of the first premolars or canines, one or two tooth lengths distally from the patient’s last remaining tooth. The MDIs were placed parallel to each other and parallel to the planned path of a new RPD insertion. In cases when the insertion torque was ≥35 Ncm, the implants were loaded early (at 6–8 weeks), and in cases when the insertion torque was lower than 35 Ncm, the MDIs were loaded three months after insertion. The standard postsurgical instructions with a detailed written description of how to maintain oral hygiene were given to the participants.
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Publication 2023
Articaine Bicuspid Bone Density Bones Canis familiaris Drill Local Anesthesia Metered Dose Inhaler Operative Surgical Procedures Oral Surgical Procedures Patients Radionuclide Imaging Saline Solution Specialists Supervision Thumb Tooth Torque
The demographic information of the patient and the classification of mandibular third molar were recorded before surgery.
The surgeries were conducted by a standard technique. The surgical technique for both sides was similar due to similar classification of the three molars of each participant, but if any changes in the protocol such as additional anesthesia were needed in the first surgery, the assistant documented it so the same protocol was performed for the second surgery. If the modifications occurred in the second surgery, the treatment was completed however the data were not analyzed. Furthermore, the duration of surgery from the first incision to the last suture was recorded.
A 10% povidone-iodine solution (Betadaine®, Nanokimia, Yazd, Iran) were used to disinfect the surgical site before surgery. The 3.6 ml of 2% lidocaine with epinephrine 1:80,000 (Xylopen®, Exir, Tehran, Iran) and 1.8 ml of 4% articaine with 1:100,000 (Dentacaine®, Exir, Boroujerd, Iran) were injected for inferior alveolar, long buccal, and lingual nerve block. A scalpal incision followed by a mesial releasing incision was made by means of blade number 15 (Novacut®, China) according to the tooth position and the full-thickness flap was elevated through Molt periosteal elevator number 9. The osteotomy of bone around the impacted tooth was performed by round carbide bur (Dentsplay, Ballaigues, Switzerland) attached to a low-speed surgical handpiece (NSK, Tokyo, Japan) as needed. Then, the tooth was sectioned employing a fissure bur (Dentsplay, Ballaigues, Switzerland) under irrigation to preserve bone as much as possible.
The proper hemostasis was achieved in the socket and the soft tissue was sutured by a violet braided synthetic absorbable polyglycolate 3.0 suture and 3/8 circle reverse cutting needle (SUPABON, Tehran, Iran). The sutures were removed after 1 week. The postoperative consideration was given in a written form designed by the first therapist. The patients were advised to have soft food on the day of surgery and the next day. Patients were asked to use an ice pack in a 20-min sequence for 24 h but not more as it is of no effect. In addition, they were told to avoid brushing the surgical site or using mouthwash, or spitting on the surgery day. They were suggested to brush the day after surgery but be careful of the sutured site. 400 mg Ibuprofen (Gelofen®, Dana, Tabriz, Iran) every 6 h for 5 days was prescribed postoperatively to reduce pain.
If the patient experienced severe pain, he/she was permitted to take 325 mg acetaminophen-codeine but his/her data were excluded from the study.
Publication 2023
acetaminophen - codeine Anesthesia Articaine Bones Epinephrine Food Gomphosis Hemostasis Ibuprofen Impacted Tooth Lidocaine Mandible Molar Molting Mouthwashes Needles Nerve Block Operative Surgical Procedures Osteotomy Pain Patients Periosteum Povidone Iodine Surgery, Day Surgical Flaps Third Molars Tissues Tongue Tooth Viola
Before the surgery, we listened carefully to the patient’s requests and explained to them the risks and possible outcomes of the procedure. The procedures were performed under local anesthesia with articaine. The range of anesthesia is on both sides of the maxillary first molar or maxillary second molar, up to the root of the nasolabial fold. The dosage was adjusted according to intraoperative patient feedback. We performed an internal beveled incision of the gingiva on the buccal side. The incision is usually up to the top of the alveolar crest, on both sides of the maxillary first molar, and to a subperiosteal depth. Precise anatomical extent and target area of filling were individualized. We then flipped the mucoperiosteal flap and exposed the maxilla (Figure 1a). On each side of the filling area, 4–8 bleeding holes were prepared with a dental drill to facilitate subsequent bone regeneration (Figure 1b). According to the preoperative evaluation, we used different amounts of Bio-Oss bone powder for augmentation to suit the specific depression of each patient. Based on the biodegradability of the Bio-Oss bone powder and previous experience, a 10% overfill was performed (Figure 1c). After the Bio-Oss bone powder was laid on the maxilla, we covered the surface with the Bio-Gide collagen membrane and fixed it with titanium screws (Figure 1d). The filling position was confirmed and adjusted by CT before and after placing the drainage strips. The surgical site was washed with normal saline. Finally, we sutured oral mucosa with 4–0 absorbable sutures.
Perioperative management includes continuous antibiotic application (tinidazole + cephalosporins) for 5 days, revisit for 3 consecutive days after the operation, and instructions for patients to avoid compression of the surgical site and large positive and negative pressure in the oral cavity for 1 week following the operation. The drainage strips were removed on postoperative day 3, and the titanium screws were usually removed 6 months after the operation.
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Publication 2023
Anesthesia Antibiotics Articaine Bio-Gide Bio-Oss Bone Regeneration Bones Cephalosporins Collagen Dental Health Services Drainage Drill Education of Patients Gingiva Local Anesthesia Maxilla Molar Mucosa, Mouth Nasolabial Fold Normal Saline Oral Cavity Patients Powder Pressure Ridge, Alveolar Surgical Flaps Sutures Tinidazole Tissue, Membrane Titanium Tooth Root
All patients underwent the same pre- and post-surgical protocol. The local anesthesia was induced by infiltration of 2 mL of Articaine 4% (40 mg/mL) and 1:100,000 Adrenalin. Full thickness mucoperiosteal flaps were raised by means of an intrasulcular and two vertical incisions.
Figure 2 was chosen as representative of the lateral surgeries performed and to show the only implant different from Sinus-Plant ones, which was inserted as part of a bridge. In this particular case, where three contiguous implants with different RBH were present and for which a different surgical approach should be suggested, the surgeon decided to perform a lateral approach to insert all the implants.
The lateral window technique for the sinus augmentation was performed by using a 1:200,000 rotary handpiece and a 2 mm round diamond bur [24 (link)]. Then, the bony window was overturned into the sinus and the membrane was elevated. The integrity of the Schneiderian membrane was ensured by covering it with a resorbable membrane (Cytoplast, RTM Collagen Membrane), and, later, the bone substitute was inserted into the sinus. As listed in Table 3, different grafting materials were used in this study, and another resorbable membrane (Cytoplast) covered the lateral bony wall. At the end, the flaps were sutured.
In both the sinus augmentation techniques, a 2 mm pilot drill was used to perforate the alveolar crest and then, twist drills of increasing diameters of the Sinus Oralplant drill kit were employed to enlarge the diameter of the osteotomy. Even the osteotomy drills presented a bunt apex to preserve the Schneiderian membrane during the preparation procedure. In performing the elevation techniques, the surgeon preferred to not involve the use of osteotomes that can fracture the internal cortex, but he rather used techniques that consumed the internal cortex, such as Ferdinando Cosci’s technique [25 (link)] or the VERSAH osseodensifying approach, conceived in 2013 by Huwais S. [26 (link)].
The Insertion Torque values (IT) were measured during the implant placement with a surgical dynamometric wrench ratchet, according to the implant system protocol [27 ,28 (link)]. In all surgeries, IT values >25 Ncm were found, and so a one-stage sinus augmentation has been performed. As a result, 3-, 4-, 5- and 6-mm length prefabricated healing abutments were placed. The dimension of such abutments was selected according to the thickness of the keratinized mucosa. Figure 3 shows a Cone-Beam Computed Tomography (CBCT) scan (NewTom Giano HR, Cefla, Imola, Italy) performed immediately post-surgery. Sutures were removed 10 days after surgery.
All the patients were advised to follow a soft diet for at least 4 weeks and to undergo antimicrobial prophylaxis with Amoxicillin 825 mg and Clavulanic Acid 125 mg (Augmentin, GlaxoSmithKline, England) twice daily for 6 days, starting on the morning of the surgery. Ketoprofen 80 mg (OKI, Dompé, Italy) was prescribed as analgesic, twice daily for 3–4 days, as needed. Sixty days after surgery, periapical x-rays were taken only to check if the osseointegration process has become established; then, provisional or definitive crowns were placed 6 months after the procedure. 6 months after surgery, the technicians created temporary bridges, cemented in the case of 2 or more implants (24 patients and 25 bridges), with silicone impression material with pick-up abutments on prefabricated cylindrical abutments screwed to 25 N. After 7 months from the procedure, the abutments were tightened (40 N), and, finally, the dental impressions were recorded using a custom trays and polyvinylsiloxane impression material. The definitive metal (cobalt-chrome)/ceramic crowns were fixed with provisional cement (TempBond: Kerr Corp. Orange, CA, USA) approximately 8 months after the implant insertion. For multiple contiguous implants, the crowns were fabricated from metal-ceramic and then splinted. The single prosthetic crowns were made in lithium-disilicate material. All final restorations were placed in full occlusion and first checked with a 20-micron thickness articulated paper and then, with an 8-micron thickness Shimstock foil (Almore International; Portland, OR, USA). All the patients were recalled for a professional cleaning treatment by a dental hygienist every 3 months.
Study data were recorded before surgery, immediately after surgery, and after 12 and 36 months during the maintenance regimen, using the paralleling technique to take periapical digital x-rays. The peri-implant bone level changes were considered as variation of the distance between the implant-abutment junction and the highest coronal point of the supporting bone. Measurements were recorded in the mesial and distal areas of the implant and then, averaged.
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Publication 2023
Amoxicillin Analgesics Articaine Augmentin Bones Bone Substitutes Clavulanic Acid Cobalt-Chromium Alloys Collagen Cone-Beam Computed Tomography Cortex, Cerebral Crowns Dental Cements Dental Impression Technique Dental Occlusion Diamond Diet Digital Radiography Drill Epinephrine Fracture, Bone Frontal Bone Hygienist, Dental Ketoprofen lithia disilicate Local Anesthesia Material, Dental Impression Metals Microbicides Mucous Membrane Operative Surgical Procedures Osseointegration Osteotomy Patients Plants Radionuclide Imaging Ridge, Alveolar Schneiderian Membrane Silicones Sinuses, Nasal Surgeons Surgical Flaps Sutures Temp-Bond Tissue, Membrane Torque Transverse Sinuses Treatment Protocols vinyl polysiloxane X-Rays, Diagnostic

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Trios 3 is a high-precision intraoral scanner designed for dental professionals. It captures detailed 3D images of teeth and oral structures with accuracy and efficiency.
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Rompun is a veterinary drug used as a sedative and analgesic for animals. It contains the active ingredient xylazine hydrochloride. Rompun is designed to induce a state of sedation and pain relief in animals during medical procedures or transportation.

More about "Articaine"

Articaine is a powerful local anesthetic widely used in dentistry and oral surgery.
It belongs to the amide class of anesthetics, providing a rapid onset and long-lasting numbing effect.
Septanest, Ubistesin forte, Ultracain DS Forte, Ubistesin, Ultracain D, and Scandonest are some brand names associated with articaine.
The anesthetic works by blocking the transmission of pain signals from the site of injection to the brain.
Phosphoric acid and Ketalar are related compounds that may be used in conjunction with articaine in certain dental procedures.
PubCompare.ai is a tool that helps researchers optimize their articaine-related studies by using AI-driven protocol comparisons to identify the most reproducible and accurate protocols from literature, preprints, and patents.
This enhances research by offering intelligent analysis and comparison tools to support articaine-related investigations.
Trios 3 is a digital dental impression system that may be used in conjunction with articaine-based procedures.
Rompun is an animal sedative that shares some similarities with articaine in its anesthetic properties.
By leveraging the insights gained from MeSH term descriptions and metadescriptions, researchers can enhance their understanding and utilization of articaine in various dental and oral surgery applications.