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CD-271

CD-271, also known as nerve growth factor receptor (NGFR), is a cell surface receptor that plays a crucial role in the development and survival of nerve cells.
This receptor is expressed in various tissues, including the nervous system, and is involved in the signaling pathways that regulate neuronal differentiation, axon growth, and neuroprotection.
CD-271 is an important target for research in the fields of neuroscience, neurodegenerative disorders, and regenerative medicine.
The PubCompare.ai platform provides a powerful AI-driven tool to optimize CD-271 research protocols, enabling scientists to easily locate relevant protocols from literature, pre-prints, and patents, and leverage AI-comparisons to identify the best approaches for their studies.
This seamless optimization tool empowers researchers to accelerate their CD-271 research and drive breakthroughs in understanding the biology and therapeutic potential of this key receptor.

Most cited protocols related to «CD-271»

Isolation and Characterization of Bone-Resident MSCs

Cited 3 times

This research was undertaken after approval from the Leeds East National Research Ethic Committee and informed written consent was obtained from all patients and healthy donors enrolled in the study. Femoral heads were obtained from patients undergoing total hip arthroplasty for primary OA (n = 26). Healthy iliac crest (IC) bone (n = 11) and femoral heads from fragility neck of femur fracture (NFF) patients (n = 3) were used as controls. Iliac crest biopsies were collected from patients undergoing orthopaedic surgery for metal removal following previous fracture, who were otherwise healthy. All bone samples were collected and processed on the day of the surgery and are detailed in the Supplementary Table S1, available at Rheumatology online. Bone-resident MSCs were extracted by 4-h enzymatic digestion [8 (link)] and cell sorting [12 (link), 13 (link)]. Following digestion, the bone fragments were rigorously washed four times in large volumes of PBS using a method modified from Pathak et al. [14 (link)] to remove all residual cellular material from the bone surface. Osteocyte-enriched bone fragments were next homogenized in lysis buffer (guanidine isothiocyanate solution with 0.4% sodium citrate, 1% N-lauryl sarcosine and 0.5% β-mercaptoethanol) and RNA was precipitated with isopropanol and DNase treated (Invitrogen, Fisher Scientific, Leicestershire, UK). Total RNA from FACS-purified CD45^-CD271⁺ MSCs and control CD45⁺CD271^- haematopoietic-lineage cells [12 (link)] was extracted using the Single-Cell RNA Extraction kit (Norgen Biotek, Geneflow, Lichfield, UK) and on-column DNase (Applied Biosystems, Foster City, California, USA) treated. cDNA was synthesized using the High-Capacity cDNA Reverse Transcription Kit (Applied Biosystems, Foster City, California, USA). qPCR was performed on a QuantStudio7Flex Real-Time PCR System (Applied Biosystems) and gene expression levels normalized relative to housekeeping gene HPRT1. The TaqMan probes for the genes of interest are detailed in Supplementary Table S2, available at Rheumatology online, all from Thermo Fisher. To evaluate multipotentiality, FACS-purified CD45^-CD271⁺ were culture-expanded and differentiated towards osteogenic, adipogenic and chondrogenic lineages as described previously [8 (link), 12 (link)].

Ilas D.C., Churchman S.M., Baboolal T., Giannoudis P.V., Aderinto J., McGonagle D, & Jones E. (2019). The simultaneous analysis of mesenchymal stem cells and early osteocytes accumulation in osteoarthritic femoral head sclerotic bone. Rheumatology (Oxford, England), 58(10), 1777-1783.

Publication 2019

2-Mercaptoethanol Adipogenesis Biopsy Bones Buffers CD-271 Cells Chondrogenesis Degenerative Arthritides Deoxyribonuclease I Digestion DNA, Complementary Donors Enzymes Ethics Committees Femoral Neck Fractures Femur Heads Fracture, Bone Gene Expression Genes Genes, Housekeeping guanidine isothiocyanate Hematopoietic System Iliac Crest Isopropyl Alcohol Metals Orthopedic Surgical Procedures Osteocytes Osteogenesis Patients Reverse Transcription Sarcosine Sodium Citrate Surgery, Day Total Hip Arthroplasty

Multiparametric Flow Cytometry of Breast Cells

Cited 3 times

Breast epithelial cells were collected by trypsinization, stained using antibodies CD49f-APC (FAB13501A), AXL-APC (FAB154A) (R&D Systems), PROCR (CD201)-PE (130–105-256), EpCAM-PE (130–091-253), EpCAM-APC (130–091-254), EpCAM- VioBlue (130–097-324) (Miltenyi Biotech Inc.), CD271-APC (345108) (Biolegend), CD44-APC (559942), CD24-PE (555428) (BD Pharmingen), Pan-Cytokeratin-FITC (F3418) (Sigma Aldrich) and ALDEFLUOR (01700) (STEMCELL Technologies), and were acquired using a BD LSR II flow cytometer. Data were analyzed using CellQuest or FlowJo software. Forward and side scatter were used to ensure that only live cells were considered in the analysis. Gating was done using appropriate FITC (555573), PE (555749), APC (555576) (BD Pharmingen) and VioBlue (130–094-670) (Miltenyi Biotech) isotype control antibodies and only a representative isotype control for two fluorescent markers are shown.
For imaging flow cytometry, 500,000–1,000,000 cells per sample were stained with the following conjugated antibodies: 1:100 mouse anti-Vimentin Clone V9-Cy3, (C-9080, Sigma-Aldrich), and 1:20 mouse anti-CD324/E-Cadherin Clone 67A4-APC, (A15717, Molecular Probes). The nucleus was stained with 1:5000 Hoechst 33342 (H-3570, Molecular Probes). Cells were fixed and permeabilized using BD Cytofix/Cytoperm solution (51–2090KZ, BD Bioscience) for 20 minutes at 4°C. Blocking was done with 5% goat serum in 1X BD Perm/Wash solution (51–2091KZ, BD Bioscience) for 15 minutes at 4°C. Single color control samples and cocktail sample with all the antibodies were incubated for 30 minutes at 4°C in dark. Cells were washed twice for 5 minutes between each step with 1x BD Perm/Wash solution. The last step of washing was done twice with 1x PBS to eliminate the detergent from the cell suspension. Cells were transferred to the UltraClear boil proof microcentrifuge tubes (Inc-607-GMT, Dot Scientific). The stained cells were stored in 1% formalin in dark at 4°C. 5000 images were analyzed using ImageStream Data Exploration and Analysis Software (IDEAS). In-focus cells were evaluated after gating on live single cells based on an aspect ratio near 1 and a low area of the bright field.

Kumar B., Prasad M., Bhat-Nakshatri P., Anjanappa M., Kalra M., Marino N., Storniolo A.M., Rao X., Liu S., Wan J., Liu Y, & Nakshatri H. (2018). Normal breast-derived epithelial cells with luminal and intrinsic subtype-enriched gene expression document inter-individual differences in their differentiation cascade. Cancer research, 78(17), 5107-5123.

Publication 2018

Antibodies Breast Cadherins CD-271 CD44 protein, human CDH1 protein, human Cell Nucleus Cells Clone Cells Cytokeratin Detergents Endothelial Protein C Receptor Epithelial Cells Flow Cytometry Fluorescein-5-isothiocyanate Formalin Furuncles Goat HOE 33342 Immunoglobulin Isotypes ITGA6 protein, human Molecular Probes Mus PROCR protein, human Progressive Encephalomyelitis with Rigidity Serum Stem Cells TACSTD1 protein, human Vimentin

Lentiviral TCR Construct Transduction

Cited 3 times

TCR constructs were subcloned into a pCCLc-MND-based lentiviral vector in the format TCRα-F2A-TCRβ-P2A-Myc271. Myc271 is a novel chimeric transduction marker comprising the transmembrane and truncated extracellular domains of CD271(LNGFR) fused to an extracellular cMyc epitope tag. Lentiviral vectors were prepared from 293T producer cells. One day prior to transfection, 1 x 10⁶ 293T cells/well were plated on 6-well plates. In 100 μL PBS, added 1 μg TCR lentivector, 1 μg pCMV-R8.2 (gag-pol helper plasmid), 0.2 μg pCAGGS-VSVG (pseudotyping helper plasmid), and 6.6 μL polyethyleneimine transfection reagent (Sigma) and incubated for 10 min. Fresh 2 mL media was replaced on plated 293T, and then transfection mix was added to cells. 48 hr following transfection, Jurkat T cells (10 (Johnson et al., 2009 (link)) cells/well in 250 μLC10) were added on a 24-well plate and 250 μL filtered (0.45 μm) viral supernatant was added to cells to initiate transduction. After 60–72 hr of transduction, Jurkats were assayed for TCR surface expression and function. To test for surface expression, cells were rinsed and stained with fluorescent antibodies and pMHC multimers in FACS buffer, and analyzed by flow cytometry. Dead cells were excluded from analysis using 7-AAD. To test for function, unselected Jurkat T cells were co-incubated in a 96-well plate at a 1:1 ratio with K562 cells stably expressing control or cognate peptide-MHC single chain trimers. After 48 hr of coincubation, the supernatant was tested for secreted interleukin-2 with a commercial ELISA kit according to the manufacturer’s protocol (BD, Franklin Lakes, NJ).

Bethune M.T., Gee M.H., Bunse M., Lee M.S., Gschweng E.H., Pagadala M.S., Zhou J., Cheng D., Heath J.R., Kohn D.B., Kuhns M.S., Uckert W, & Baltimore D. (2016). Domain-swapped T cell receptors improve the safety of TCR gene therapy. eLife, 5, e19095.

Publication 2016

7-aminoactinomycin D Antigen T Cell Receptor, beta Chain Buffers CD-271 Cells Chimera Cloning Vectors Enzyme-Linked Immunosorbent Assay Epitopes Flow Cytometry Fluorescent Antibody Technique HEK293 Cells Interleukin-2 Jurkat Cells K562 Cells Peptides Plasmids Polyethyleneimine Transfection

Quantifying Mesenchymal Stem Cell Proliferation

Cited 3 times

A CFU‐F assay was performed as described previously 11, with a minor modification using methylene blue, before scoring was performed in a blinded manner. MSC expansion was used to measure MSC proliferation rates and to produce a sufficient number of cells for trilineage differentiation assays and gene expression analysis. MSCs were expanded in StemMACS MSC Expansion Media after preenrichment using CD271 MACSelect MicroBeads (both from Miltenyi Biotec), and culture population doublings were calculated as previously described 20. MSCs from the bone of healthy controls and patients with OP were expanded similarly following their enzymatic release from bone 11.

Campbell T.M., Churchman S.M., Gomez A., McGonagle D., Conaghan P.G., Ponchel F, & Jones E. (2016). Mesenchymal Stem Cell Alterations in Bone Marrow Lesions in Patients With Hip Osteoarthritis. Arthritis & Rheumatology (Hoboken, N.j.), 68(7), 1648-1659.

Publication 2016

Biological Assay Bones CD-271 Enzymes Gene Expression Profiling Methylene Blue Microspheres Patients

Caspase-3/7 Activity Assay for CD271+ MSCs

Cited 2 times

Protocol full text hidden due to copyright restrictions

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Publication 2021

Biological Assay Caspase-7 Caspase 3 CD-271 Cells Colorimetry Mus Serum Streptomycin

Most recents protocols related to «CD-271»

Multiparameter Flow Cytometry of Chondrocyte and Stromal Markers

Cells in suspension were stained for 30 min at 4 °C in the dark with the following antibodies: chondrocyte (CD44-PE Vio770 clone REA690, CD73-PE clone REA804, CD90-FITC clone REA897, CD105-PerCP Vio700 clone REA794) markers, hemato/endothelial (CD31-PerCP Vio700 clone REA730, CD34-FITC clone AC136, CD45-PE Vio770 clone REA747) markers and bone marrow mesenchymal stromal cell (CD271-PE clone REA844) markers (all from Miltenyi Biotec, Bergisch Gladbach, Germany). After the cell wash with FACS buffer (phosphate buffer, 5% FBS, 0.1% sodium azide), cells were detected by flow cytometry using a CytoFLEX flow cytometer (Beckman Coulter, Fullerton, CA, USA). The following antibody combinations were used: CD73/90/105/44 and CD34/271/31/45 (FITC, PE, PC5 and PC7 channels, respectively, for both combinations).

Ragni E., De Luca P., Valli F., Zagra L, & de Girolamo L. (2023). Inflammatory Treatment Used to Mimic Osteoarthritis and Patients’ Synovial Fluid Have Divergent Molecular Impact on Chondrocytes In Vitro. International Journal of Molecular Sciences, 24(3), 2625.

Publication 2023

Antibodies Bone Marrow Stromal Cells Buffers CD-271 CD44 protein, human Cells Chondrocyte Clone Cells Endothelium Flow Cytometry Fluorescein-5-isothiocyanate Immunoglobulins Mesenchyma NT5E protein, human Phosphates Sodium Azide Thy-1 Antigens

Identification and Sorting of Epidermal Progenitors

Each sample was transferred to a collection tube and resuspended in PBS/1% BSA/5mM EDTA. Fluorescently tagged antibodies were added at concentrations presented in Table 3 and incubated for 30 min on ice. Labeled cells were washed three times with PBS to remove unbound antibody and resuspended in flow buffer (PBS with 2% BSA, 1 mM EDTA, and 1 μg/mL DAPI). Cells were sorted on a BD FacsAria III. LEps were defined as CD133+ /CD271− cells, and MEps were defined as CD133−/CD271+ cells, with DAPI + cells discarded. Compared to cells from standard 2-D cultures, postconfluent cells exhibit marked autofluorescence.

Todhunter M.E., Miyano M., Carlson E.G., Hinz S, & LaBarge M.A. (2023). Sustained postconfluent culture of human mammary epithelial cells enriches for luminal and c-Kit+ subtypes. Breast Cancer Research : BCR, 25, 6.

Publication 2023

Antibodies Buffers CD-271 Cells CTSL protein, human DAPI Edetic Acid Immunoglobulins LEP protein, human

Characterization of Glioblastoma Cell Populations

Patient-derived GBM cells (U3034MG, U3088MG, and U3031MG)
or glioma cells (GCs) were grown in 6-well plates (50,000 cells/well),
coated with poly-l-ornithine (15 μg/mL) and laminin
(10 μg/mL), and grown to a confluency of 80%. Cells were expanded
in medium containing neurobasal, DMEM:F12 glutamax, media supplements,
and EGF and FGF (10 μg/mL, 1:1000) every 72 h. The plates were
incubated with p-HTMI (stock solution of 1 mg/mL in deionized water,
diluted 1:500) for 10 min, then incubated with Accutase for 7 min,
and resuspended in cell culture medium. Cells were spun down at 1500
rpm for 5 min. Further, they were incubated with binding buffer (BSA,
0.5 M EDTA, and PBS) (100 μL/sample) and CD133-APC (130-090-826
Mitenyi Biotec) (10 μL/sample), incubated for 10 min at 4 °C,
and washed with PBS prior to FACS analysis. Cells were incubated with
CD44 (45-0441 eBioscience) diluted in binding buffer and used at a
concentration of 1:10,000. The same antibody conditions as CD133 were
used for CD44 i.e. 100 μL of binding buffer, incubated for 10
min at 4 °C, and washed with PBS prior to FACS analysis. Cells
were also double stained for p-HTMI and CD271 (560834 BD Pharmingen),
5 μL/sample with the same antibody conditions as CD133. U-87MG
cells were expanded as previously described^{26 (link)} and incubated with the same conditions of p-HTMI and CD133 and CD44
as described for GCs. To verify cell necrosis, lysis buffer was added
with 5 μL of PI per sample, and for cell apoptosis, cells were
incubated with 100 μL of 1X annexin V binding buffer and 5 μL
of APC annexin V per sample (561012 BD Pharmingen) and incubated for
15 min. The analysis was carried out on an FACS LSRII flow cytometer
equipped with FACSDiva software. Patient tissue collection and use
were in accordance with ethical permit EPN Uppsala 2007/353 and its
addendum Oct. 28, 2013.

Ilkhanizadeh S., Gracias A., Åslund A.K., Bäck M., Simon R., Kavanagh E., Migliori B., Neofytou C., Nelander S., Westermark B., Uhrbom L., Forsberg-Nilsson K., Konradsson P., Teixeira A.I., Uhlén P., Joseph B., Hermanson O, & Nilsson K.P. (2023). Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative. ACS Applied Bio Materials, 6(9), 3790-3797.

Publication 2023

accutase Annexin A5 Apoptosis Buffers CD-271 CD44 protein, human Cell Culture Techniques Cells Culture Media Dietary Supplements Edetic Acid Glioma Immunoglobulins Laminin Necrosis Patients polyornithine

Multicolor Flow Cytometry for Cellular Profiling

Flow cytometry was performed with LSRFortessa (Becton–Dickinson). In detail, 2 × 10⁶ cells each were stained in three different multicolor panels, comprised of markers for HSPCs and endothelial progenitor cells (EPCs), immune cell subsets and MSCs and their precursors, followed by RBC lysis (BD Pharm Lyse™ Lysing Buffer, BD Biosciences, Heidelberg, Germany).
For detection and quantification of HSPCs and EPCs, cells were stained with 7-AAD viability dye (BioLegend, San Diego, CA, USA) and the following antibodies (all from BioLegend, unless otherwise noted): anti-CD14-APC-Cy7 (63D3), anti-CD31-Brilliant Violet 605™ (WM59), anti-CD34-Alexa Fluor® 700 (581), anti-CD45-V500 (HI30, BD Horizon™), anti-CD117-Alexa Fluor® 488 (104D2), anti-CD133-Brilliant Violet 421™ (clone 7), and anti-CD309-PE (7D4-6).
For analysis of immune cell subsets, cells were stained with 7-AAD viability dye and the following antibodies (all from BioLegend): anti-CD3-Pacific Blue (HIT3a), anti-CD4-Alexa Fluor® 700 (SK3), anti-CD8-Brilliant Violet 510™ (SK1), anti-CD11b-PE-Cy7 (LM2), anti-CD14-APC-Cy7 (63D3), anti-CD19-PE (HIB19), anti-CD45-FITC (HI30), anti-CD56-Alexa Fluor® 647 (5.1H11), anti-CD183-Brilliant Violet 605™ (G025H7), and anti-CD194-PE-Dazzle™ 594 (L291H4).
MSCs and their precursors were detected in the BM aspirates by staining with 7-AAD viability dye and the following antibodies (all from BioLegend, unless otherwise noted): anti-CD29-APC-Cy7 (TS2/16), anti-CD34-Alexa Fluor® 700 (581), anti-CD45-FITC (HI30), anti-CD73-Brilliant Violet 605™ (AD2), anti-CD90-PE-Cy7 (5E10, BD Horizon™), anti-CD105-PE-CF594 (266, BD Horizon™), anti-CD119-PE (GIR-208), anti-CD146-Brilliant Violet 510™ (P1H12), and anti-CD271-BV421 (C40-1457, BD Horizon™).
Flow cytometry data were analyzed using FCS Express 6 Flow Software (De Novo Software, Pasadena, CA, USA). The percentages of viable cells of each cell type were converted to cell count per milliliter processed BM.

Epah J., Spohn G., Preiß K., Müller M.M., Dörr J., Bauer R., Daqiq-Mirdad S., Schwäble J., Bernas S.N., Schmidt A.H., Seifried E, & Schäfer R. (2023). Small volume bone marrow aspirates with high progenitor cell concentrations maximize cell therapy dose manufacture and substantially reduce donor hemoglobin loss. BMC Medicine, 21, 360.

Publication 2023

7-aminoactinomycin D alexa fluor 488 Alexa Fluor 647 Antibodies Buffers CD-271 Cells Clone Cells CXCR3 protein, human Endothelial Progenitor Cells Flow Cytometry Fluorescein-5-isothiocyanate ITGAM protein, human Muromonab-CD3 NT5E protein, human Thy-1 Antigens vascular endothelial growth factor receptor-2, human Viola

Large-Scale CD4+ T Cell Expansion and Cryopreservation

Protocol full text hidden due to copyright restrictions

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Publication 2023

Bioreactors CD-271 CD4 Positive T Lymphocytes Cells Electroporation Freezing Leukapheresis Males Microspheres Nitrogen Prodigy Saline Solution Sulfoxide, Dimethyl Wolves

Top products related to «CD-271»

Facscalibur by BD

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The FACSCalibur is a flow cytometry system designed for multi-parameter analysis of cells and other particles. It features a blue (488 nm) and a red (635 nm) laser for excitation of fluorescent dyes. The instrument is capable of detecting forward scatter, side scatter, and up to four fluorescent parameters simultaneously.

Bovine serum albumin (bsa) by Merck Group

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Bovine serum albumin (BSA) is a common laboratory reagent derived from bovine blood plasma. It is a protein that serves as a stabilizer and blocking agent in various biochemical and immunological applications. BSA is widely used to maintain the activity and solubility of enzymes, proteins, and other biomolecules in experimental settings.

Cd271 by BD

Sourced in United States

The CD271 is a laboratory equipment product that measures the expression of the CD271 antigen, also known as the low-affinity nerve growth factor receptor (LNGFR). It is a cell surface receptor that is involved in various cellular processes. The CD271 product provides researchers with a tool to study the expression and function of this important cell surface marker.

Cd271 pe by Miltenyi Biotec

Sourced in Germany

CD271-PE is a fluorescent-labeled antibody used for the detection and identification of cells expressing the CD271 antigen, also known as the low-affinity nerve growth factor receptor (LNGFR) or p75 neurotrophin receptor (p75NTR). It can be used in flow cytometry applications for the analysis of cell populations.

Cd271 by Miltenyi Biotec

Sourced in United Kingdom

CD271, also known as the low-affinity nerve growth factor receptor (LNGFR), is a cell surface marker that can be used to identify and isolate specific cell populations. It is a transmembrane glycoprotein that plays a role in the regulation of cell growth, survival, and differentiation. This product can be used for flow cytometry, cell sorting, and other applications where the identification and isolation of CD271-positive cells is required.

Cd73 pe by BD

Sourced in United States, Germany, United Kingdom, France

CD73-PE is a fluorochrome-conjugated antibody that binds to the CD73 protein. CD73 is an enzyme involved in the conversion of extracellular adenosine monophosphate to adenosine. This product can be used for the identification and analysis of cells expressing CD73 using flow cytometry.

Facsaria 3 by BD

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The FACSAria III is a high-performance cell sorter designed for advanced flow cytometry applications. It features a robust and flexible optical system, enabling precise cell sorting and analysis. The core function of the FACSAria III is to provide users with the ability to sort and analyze complex cell samples with high accuracy and efficiency.

Cd271 apc by Miltenyi Biotec

Sourced in Germany, United Kingdom

CD271-APC is a fluorochrome-conjugated antibody specific for the CD271 (p75 NGFR) cell surface marker. CD271 is expressed on various cell types, including nerve cells and their progenitors. The APC (allophycocyanin) fluorochrome allows for detection of CD271-positive cells using flow cytometry or other fluorescence-based applications.

Facsaria 2 by BD

Sourced in United States, Germany, United Kingdom, Japan, Belgium, China, Canada, Italy, France, South Sudan, Singapore, Australia, Denmark, Uruguay

The FACSAria II is a high-performance cell sorter produced by BD. It is designed for precision cell sorting and analysis. The system utilizes flow cytometry technology to rapidly identify and separate different cell populations within a sample.

Facsdiva software by BD

Sourced in United States, Germany, United Kingdom, France, Canada, Belgium, Australia, Italy, Spain, Switzerland, China, Netherlands, Finland, Japan, Jersey, Lao People's Democratic Republic

FACSDiva software is a user-friendly flow cytometry analysis and data management platform. It provides intuitive tools for data acquisition, analysis, and reporting. The software enables researchers to efficiently process and interpret flow cytometry data.

What is CD-271 and what is its significance in research?

How can PubCompare.ai help with CD-271 research?

PubCompare.ai allows you to screen protocol literature more efficiently and leverage AI to pinpoint critical insights. The platform can help researchers identify the most effective protocols related to CD-271 for their specific research goals. The platform's AI-driven analysis can highlight key differences in protocol effectiveness, enabling you to choose the best option for reproducibility and accuaracy.

What are some common usage challenges with CD-271 research?

One of the key challenges in CD-271 research is identifying the most effective and reliable protocols from the vast amount of available literature, pre-prints, and patents. Researchers need to compare various protocols to determine the best approach for their specific research goals, which can be time-consuming and complex. PubCompare.ai helps overcome this by providing an AI-driven platform that can quickly identify the most relevant and effective protocols, enabling researchers to make informed decisions and accelerate their CD-271 studies.

Are there different variations or types of CD-271 that researchers should be aware of?

Yes, there are different forms or variants of CD-271 that may be relevant for specific research applications. For example, some studies may focus on the full-length receptor, while others may investigate truncated or modified versions of CD-271. Understanding these variations and their potential impacts on research outcomes is important, and PubCompare.ai can help researchers navigate the complexities by providing AI-driven insights on the most suitable protocols for their particular CD-271 targets.

What are some specific applications of CD-271 research?

CD-271 research has a wide range of applications, including: 1. Neurodegenerative disorders: Investigating the role of CD-271 in the pathogenesis and potential treatment of neurodegenerative diseases, such as Alzheimer's, Parkinson's, and Huntington's. 2. Nerve regeneration: Exploring the use of CD-271 in promoting axon growth and nerve repair, with potential applications in spinal cord injury and peripheral nerve damage. 3. Stem cell research: Studying the involvement of CD-271 in the differentiation and survival of neural stem cells, which could lead to advancements in regenerative medicine. 4. Cancer research: Investigating the role of CD-271 in certain types of cancer, such as neuroblastoma, and its potential as a therapeutic target.

More about "CD-271"

Discover the power of PubCompare.ai, the AI-driven platform that optimizes your nerve growth factor receptor (NGFR) research protocols.
Also known as CD-271, this cell surface receptor plays a crucial role in the development and survival of nerve cells, and is expressed in various tissues, including the nervous system.
It is involved in the signaling pathways that regulate neuronal differentiation, axon growth, and neuroprotection, making it an important target for research in the fields of neuroscience, neurodegenerative disorders, and regenerative medicine.
Easily locate relevant protocols from literature, pre-prints, and patents, and leverage AI-driven comparisons to identify the best approaches for your CD-271 studies.
This seamless optimization tool empowers researchers to accelerate their NGFR research and drive breakthroughs in understanding the biology and therapeutic potential of this key receptor.
Explore the FACSCalibur and FACSAria III flow cytometry systems, as well as the FACSAria II and FACSDiva software, to analyze and sort cells expressing CD271 and CD73.
Utilize bovine serum albumin (BSA) to optimize your cell staining and sorting protocols.
Experience the power of PubCompare.ai and unlock new possibilities in your CD271-related research.