Charcoal, Activated
This highly adsorbent material is created through thermal or chemical activation processes that increase its surface area and enhance its ability to trap and remove impurities.
Activated charcoal is commonly used in emergency settings to treat poisoning and drug overdoes, as well as in chronic conditions to manage gastrointestinal issues.
Reasearchers can leverage PubCompare.ai's AI-powered comparison tool to streamline their work on activated charcoal, easily locating and comparing protocols from literature, preprints, and patents to identify the best methodologies and products.
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Polyethylene glycol (PEG)-alginate was prepared by coupling PEG-amine (5 kDa, Laysan Bio) to the low molecular weight alginate (35 kDa) using carbodiimide chemistry with a similar procedure to the RGD coupling3 (link). In brief, 295 mg of PEG-amine was mixed with 50 mL of 10 mg/mL alginate in 0.1 M MES (2-(N-morpholino)ethanesulfonic acid, Sigma-Aldrich) buffer at pH 6.5. Then 242 mg of EDC (N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride, Sigma-Aldrich) and 137 mg of Sulfo-NHS (N-hydroxysulfosuccinimide, Thermo Fisher Scientific) were added into the solution. The reaction was carried out for 20 hours under constant stirring. The product was dialyzed against deionized water for 3 days (molecular weight cutoff of 10 kDa), filtered with activated charcoal, sterile filtered, and lyophilized. The structure of the PEG-alginate was confirmed with nuclear magnetic resonance (NMR) and gel permeation chromatography (GPC). Based on the change of molecular weight of alginate before and after PEG coupling (from 35 kDa to 45 kDa), an average of 2 PEG molecules were coupled to 1 alginate chain. This number was confirmed by 1H NMR spectroscopy (
Most recents protocols related to «Charcoal, Activated»
Example 2
A mixture obtained by mixing 100 parts by mass of granular coal pitch having a softening point of 280° C. as an organic material with 0.9 part by mass of tris(2,4-pentanedionato)iron(III) (metal species: Fe) was fed into a melt extruder, where it was melted and mixed at a melting temperature of 320° C., and spun at a discharge rate of 16 g/min to obtain a pitch fiber. The pitch fiber was subjected to an infusibilization treatment by heating for 54 minutes, to 354° C. from ambient temperature in the air at a rate of 1 to 30° C./minute, to obtain an infusibilized pitch fiber as an activated carbon precursor. The iron (Fe) content in the activated carbon precursor was 0.11% by mass.
The activated carbon precursor was activated by conducting a heat treatment at an atmospheric temperature of 950° C. for 40 minutes, while continuously introducing a gas having a CO2 concentration of 100% by volume into an activation furnace, to obtain an activated carbon of Example 2. In the activated carbon, the pore volume A of pores with a size of 1.0 nm or less was 0.396 cc/g, the pore volume B of pores with a size of 3.0 nm or more and 3.5 nm or less was 0.016 cc/g, the iron content was 0.251% by mass, and the average fiber diameter was 13.6 μm.
Granular coal pitch having a softening point of 280° C. as an organic material was fed into a melt extruder, where it was melted and mixed at a melting temperature of 320° C., and spun at a discharge rate of 20 g/min, to obtain a pitch fiber. The pitch fiber was subjected to an infusibilization treatment by heating for 54 minutes, to 354° C. from ambient temperature in the air at a rate of 1 to 30° C./minute, to obtain an infusibilized pitch fiber as an activated carbon precursor. The iron content in the activated carbon precursor was 0% by mass.
The activated carbon precursor was activated by conducting a heat treatment at an atmospheric temperature of 875° C. for 40 minutes, while continuously introducing a gas having an H2O concentration of 100% by volume into an activation furnace, to obtain an activated carbon of Comparative Example 2. In the activated carbon, the pore volume A of pores with a size of 1.0 nm or less was 0.401 cc/g, the pore volume B of pores with a size of 3.0 nm or more and 3.5 nm or less was 0.000 cc/g, the iron content was 0% by mass, and the average fiber diameter was 16.7 μm.
Example 6
A mixture obtained by mixing 100 parts by mass of granular coal pitch having a softening point of 280° C. as an organic material with 0.3 part by mass of tris(acetylacetonato)yttrium was fed into a melt extruder, where it was melted and mixed at a melting temperature of 320° C., and spun at a discharge rate of 20 g/min to obtain a pitch fiber. The pitch fiber was subjected to an infusibilization treatment by heating for 54 minutes, to 354° C. from ambient temperature in the air at a rate of 1 to 30° C./minute, to obtain an infusibilized pitch fiber as an activated carbon precursor. The yttrium content in the activated carbon precursor was 0.06% by mass.
The activated carbon precursor was activated by conducting a heat treatment at an atmospheric temperature of 950° C. for 60 minutes, while continuously introducing a gas having a CO2 concentration of 100% by volume into an activation furnace, to obtain an activated carbon of Comparative Example 6. In the activated carbon, the pore volume A of pores with a size of 1.0 nm or less was 0.429 cc/g, the pore volume B of pores with a size of 3.0 nm or more and 3.5 nm or less was 0.000 cc/g, the yttrium content was 0.15% by mass, and the fiber diameter was 18.2 μm.
Example 1
General Treatment Regimen
Surgical treatment of a wound may be required before starting therapy. The wound area is opened as completely as possible. General surgical debridement is performed. Avital tissue and bone parts are removed if necessary. This serves as a first reduction of the germ load and prepares the wound bed. After sufficient hemostasis has been achieved, a first dressing (activated carbon NPWT) can be applied.
The combination therapy according to the invention is usually carried out in the outpatient department. Thanks to this less painful procedure, analgesics or even anesthesia standby can generally be dispensed with. Dressing changes are carried out under sterile conditions (sterile gloves, work surfaces, face masks). For this reason, two people are optimally required to carry out this therapy quickly and safely.
The significance of the model coefficients was validated using multiple linear regression, where the determination coefficients R2 were calculated for each model coefficient by omitting the term from the overall model. A minimum value for R2 of 0.80 is required to mark a good fit28 . In addition, a t-test was performed to assess the significance of the model coefficients, which were displayed as error bars in the bar charts. If the error bar exceeds the zero line, the model coefficient is considered insignificant and was discarded to avoid overfitting. All parameters were recalculated subsequently. An overview of the discarded model coefficients for each response and the corresponding determination coefficients is given in Table
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More about "Charcoal, Activated"
This material is created through thermal or chemical activation processes, which increase its surface area and enhance its ability to trap and remove impurities.
Activated charcoal has a long history of use in medical and industrial settings.
In emergency situations, it is commonly used to treat poisoning and drug overdoses by adsorbing toxins and preventing their absorption in the gastrointestinal tract.
It is also used to manage chronic gastrointestinal issues, such as diarrhea, gas, and bloating.
Beyond its medical applications, activated charcoal is used in water and air purification, as well as in the removal of contaminants from various liquids and gases.
Researchers can leverage the power of PubCompare.ai's AI-driven protocol comparison tool to streamline their work on activated charcoal, easily locating and comparing protocols from literature, preprints, and patents to identify the best methodologies and products.
The production of activated charcoal typically involves the use of materials such as hydrochloric acid, sodium hydroxide, ethanol, DMSO, NaCl, PVDF, methanol, and potassium hydroxide, among others.
These substances play a crucial role in the activation and modification of the charcoal to enhance its adsorptive properties and performance.
By utilizing PubCompare.ai's advanced tools, researchers can optimize their investigations on activated charcoal, making data-driven decisions and streamlining their research efforts.
The availability of AI-powered insights and the ability to compare protocols from various sources can be invaluable in advancing the understanding and applications of this versatile material.