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Cinnamic acid

Cinnamic acid is a naturally occuring organic compound found in various plants, including cinnamon and other aromatic herbs.
It is a white crystalline substance with a characteristic cinnamony odor.
Cinnamic acid has a diverse range of biological activities and is used in the synthesis of many pharmaceuticals, fragrances, and other chemical products.
It plays a role in plant defense mechanisms and has been studied for its potential antioxidant, anti-inflammatory, and antimicrobial properties.
Reserach into the applications and effects of cinnamic acid is an active area of scientific inquiry.

Most cited protocols related to «Cinnamic acid»

MALDI-TOF Mass Spectrometry Imaging

Cited 9 times

Cryosections of the tissues were cut in a cryo-microtome (Leica CM1900-UV) at a thickness of 10 μm and transferred onto conductive indium-tin-oxide-coated glass slides (Bruker Daltonik, Bremen, Germany). The sections were vacuum-dried in a desiccator for approximately 15 min then washed two times in 70% ethanol and once in 96% ethanol for 1 min each. The sections were then dried and stored under vacuum until the matrix was applied.
The sections were coated with matrix using an ImagePrep (Bruker Daltonik) according to the manufacturer's standard protocols. The brain and testis samples were coated with α-cyano-4-hydroxy-cinnamic acid (Bruker Daltonik), while the pancreas sample was coated with sinapinic acid (Bruker Daltonik).
All mass spectra were acquired in linear mode on autoflex or ultraflex instruments equipped with smartbeam (pancreas) or smartbeam II lasers (all other samples; Bruker Daltonik). For each pixel, 200 laser shots were accumulated at constant laser energy.

Deininger S.O., Cornett D.S., Paape R., Becker M., Pineau C., Rauser S., Walch A, & Wolski E. (2011). Normalization in MALDI-TOF imaging datasets of proteins: practical considerations. Analytical and Bioanalytical Chemistry, 401(1), 167-181.

Publication 2011

Brain cinnamic acid Cryoultramicrotomy Electric Conductivity Ethanol indium tin oxide Mass Spectrometry Microtomy Pancreas sinapinic acid Testis Tissues Vacuum

Phenylalanine Ammonia-Lyase Activity Assay

Cited 9 times

PAL activity was measured according to Zucker (1965 (link)), with some modifications. The cells were homogenized in an ice-cold mortar with 5 ml 0.05 M Tris–HCl buffer pH 8.0 containing 0.8 mM β-mercaptoethanol and 1 % w/v polyvinylpolypyrrolidone. The homogenate was centrifuged (18,000×g for 15 min at 4°C) and the supernatant was used to measure PAL activity. The enzyme reaction mixture consisted of 1 ml 0.05 M Tris–HCl buffer pH 8.0, 0.1 ml enzyme extract, 0.5 ml of 10 mM l-phenylalanine, and water to a total volume of 3 ml. After 1 h incubation at 37°C, the reaction was stopped by the addition of 0.1 ml 1 N HCl, and the absorbance was read at 290 nm on a NANODROP 2000C spectrophotometer (Thermo Scientific, Waltham, MA). The enzyme activity was expressed in units, each representing the amount of enzyme catalyzed for the formation of 1 μM of trans-cinnamic acid (ε = 9,000 M ml⁻¹) per min per milligram protein. The experiment was performed in duplicate with two flasks sampled for each repetition.

Sykłowska-Baranek K., Pietrosiuk A., Naliwajski M.R., Kawiak A., Jeziorek M., Wyderska S., Łojkowska E, & Chinou I. (2012). Effect of l-phenylalanine on PAL activity and production of naphthoquinone pigments in suspension cultures of Arnebia euchroma (Royle) Johnst. In Vitro Cellular & Developmental Biology, 48(5), 555-564.

Publication 2012

2-Mercaptoethanol Cells cinnamic acid Cold Temperature enzyme activity Enzymes Phenylalanine polyvinylpolypyrrolidone Proteins Tromethamine

MALDI-MS Analysis of DNA Adducts

Cited 7 times

Calf thymus DNA, 2´-deoxycytidine-5´-monophosphate, disodium salt (dCMP), hydroquinone, p-benzoquinone, nuclease P1, ferric chloride, triethylammonium acetate buffer (TEAA, 1M), 2-N-(morpholino)ethanesulfonic acid (MES), 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC), α-cyano-4-hydroxy-cinnamic acid (CCA), and ammonium citrate (dibasic) were from Sigma-Aldrich (St. Louis, MO). 5-Methyl-2´-deoxycytidine-5´-monophosphate, disodium salt (mdCMP) was a gift from Affymetrix (Cleveland, Ohio). Phosphodiesterase I was from Worthington (Lakewood, NJ). BIOMAX-5 Ultrafree MC centrifugal filter devices were from Millipore (Billerica, MA). Propanesulfonic acid silica was from J. T. Baker (Phillipsburg, NJ). Microcentrifuge tubes, pipetter tips, and HPLC grade acetonitrile (ACN) were from Fisher Scientific (Pittsburgh, PA). The OASIS columns were from Waters (Milford, MA). All materials were used as received. Benzoylhistamine (BH), benzoylhistamine-d₄ (BH(d₄), where the ethylene moiety is tetradeuteriated), and p-bromo-benzoylhistamine (Br-BH) were synthesized as described.⁹Hydroquinone was reacted in the presence of ferric chloride with calf thymus DNA as described.^{10 (link)} Our method for measuring DNA adducts, described before,^{8 (link),9} is summarized here. The digestion of the modified DNA to nucleotides was done with nuclease P1 at pH 5.5 followed with phosphodiesterase I at pH 9, 3 hours at 45 °C for both. The sample was purified with an OASIS column (186000383, Waters) and dried. The labeling reaction was performed by adding 3.5 μL of 12 mM BH (6 mM BH and 6 mM BH(d₄)), or 12 mM Br-BH, and 3.5 μL of 80 mM EDC in 0.01 M MES buffer at pH 6, to the dried OASIS collection vial, and then, after mixing, the sample was kept at room temperature in the dark for 3 hours. The sample was separated on a capillary HPLC column (PepMap 180 μm I.D×150 mm, Dionex, Sunnyvale, CA) using a gradient flow from 3% to 60 % ACN in 40 min at 2.2 μL/min. A droplet was collected onto a MALDI plate every 20 sec with a Probot Fraction Collector (Dionex, Sunnyvale, CA). CCA matrix (0.5 μL, 5 mg/mL in ACN:water, 50:50, v/v, with 2.5 mM of ammonium citrate, dibasic) was deposited onto each dried spot, followed by air-drying for 5 min. Analysis was done on a Voyager DE STR MALDI-TOF-MS or a Model 5800 MALDI-TOF/TOF-MS (AB SCIEX, Foster City, CA) in a negative ion mode with a delay time of 150 ns. Each sample well was surveyed to find a “sweet spot”, and then 400 laser pulses were averaged to generate a spectrum. MS/MS was performed with a medium pressure of air and a mass resolution window of 400 with the metastable-ion suppressor on.
p-Benzoquinone was reacted with dCMP or mdCMP as described.^{13 (link)} The nucleotide (8 mg of dCMP or 8.3 mg of mdCMP, 0.023 mmol) and p-benzoquinone (16 mg, 0.15 mmol) were allowed to react in 1 mL of 0.1 M sodium acetate buffer (pH 5) at 37 °C. After 17 h, the diluted reaction mixture (1:100 in water) was mixed with CCA matrix in a 1:5 ratio and subjected to MALDI-TOF-MS in a negative ion mode. Also, MS/MS in a positive ion mode was performed on the protonated modified nucleobase formed in MALDI ion source. Further, a combined sample (1 μL of each diluted reaction mixture) was labeled with Br-BH and subjected to MALDI analysis directly.

Wang P., Gao J., Li G., Shimelis O, & Giese R.W. (2012). Nontargeted Analysis of DNA Adducts by Mass-Tag MS: Reaction of p-Benzoquinone with DNA. Chemical research in toxicology, 25(12), 2737-2743.

Publication 2012

Phytohormone Extraction from Medicago truncatula

Cited 6 times

Leaves of M. truncatula were excised and immediately submerged in liquid nitrogen before storage at −80 °C. For the extraction of phytohormones, the leaf tissues were first ground to a fine powder in the presence of liquid nitrogen by mortar and pestle and 100 mg transferred to a two mL microcentrifuge tube. The extraction and combined derivatisation proceeded as described by Villas-Bôas et al. (2003 (link)), with some modification. To the ground tissue, 20 µL of 20 µg mL⁻¹ deuterated cinnamic acid (CA-_d6; in methanol) was directly added and the sample suspended in 200 μL of a sodium hydroxide (1 % w/v) solution. Added to the suspension were 147 µL of methanol and 34 µL of pyridine, before vigorous mixing by vortex for 25–30 s. Methyl chloroformate (20 µL) was then added and the suspension vigorously mixed for 25–30 s. A second volume of methyl chloroformate (20 μL) was added and the samples again mixed for 25–30 s. Subsequently, chloroform (400 µL) was added, the sample mixed for 10 s and a 50 mM sodium bicarbonate solution (400 µL) added. Following further mixing for 10–15 s, the extract was separated into two phases by centrifugation for 30 s at 16,100×g. The lower organic layer containing the phytohormones was transferred by pipette to a fresh microcentrifuge tube, being careful not to disturb the layer of plant debris separating the aqueous and organic layers. Anhydrous sodium sulphate was then added until the crystalline sodium sulphate appeared dry upon further addition. One hundred microlitre of the water-free solution was transferred to a glass analytical vial for GC–MS analysis.

Rawlinson C., Kamphuis L.G., Gummer J.P., Singh K.B, & Trengove R.D. (2015). A rapid method for profiling of volatile and semi-volatile phytohormones using methyl chloroformate derivatisation and GC–MS. Metabolomics, 11(6), 1922-1933.

Publication 2015

Bicarbonate, Sodium Centrifugation Chloroform cinnamic acid Gas Chromatography-Mass Spectrometry Methanol methyl chloroformate Nitrogen Plant Growth Regulators Plant Leaves Plants Powder pyridine Sodium Hydroxide sodium sulfate Tissues

Mass Spectrometric Analysis of DNA Adducts

Cited 6 times

The Qiagen Blood & Cell Culture Maxi Kit was purchased from Qiagen (Valencia, CA). Nuclease P1, 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC), 2-N-(morpholino)ethanesulfonic acid (MES), α-cyano-4-hydroxy-cinnamic acid (CCA), ammonium citrate (dibasic), triethylammonium acetate buffer (TEAA, 1M), 5-hydroxymethyl-2′-deoxyuridine, thymidine-5′-monophosphate (TMP) and triethylammonium bicarbonate buffer (1M) were from Sigma (St. Louis, MO). Phosphodiesterase I was from Worthington (Lakewood, NJ). BIOMAX-5 Ultrafree MC centrifugal filter devices were from Millipore (Billerica, MA). Propanesulfonic acid silica was from J. T. Baker (Phillipsburg, NJ). Microcentrifuge tubes, pipetter tips, and HPLC grade acetonitrile (ACN) were from Fisher Scientific (Pittsburgh, PA). All materials were used as received. Human placenta from a smoker was obtained from the National Disease Research Interchange (Philadelphia, PA). Benzoylhistamine (BH) and d4-benzoylhistamine (d4-BH) were synthesized as described.¹² ThymineGlycolThymineDimer (0801215) was a gift from ZeptoMetrix (Buffalo, NY). CS Chem3D Pro software was from CambridgeSoft Corporation (Cambridge, MA).
DNA was isolated using a Qiagen Blood & Cell Culture Maxi Kit. Digestion of 25 μg of DNA to nucleotides was done with nuclease P1 at pH 5.5 followed with phosphodiesterase I at pH 9, 3 hours at 45 °C for both. The DNA digest was filtered with a Ultrafree-MC Biomax-5 Membrane 5 kDa filter.
Digested DNA (3 μg aliquot) was dried, and redissolved in 20 μL of 80 mM triethylammonium bicarbonate buffer for HPLC separation, using an XBridge C18 column (1×150 mm, 3.5 μm). The gradient flow rate was 30 μL/min, from 1% to 30 % ACN in 30 min, with 20 mM triethylammonium bicarbonate buffer at pH 8.5. Based on monitoring by absorbance, fractions were collected between the peaks for the four major normal nucleotides, and evaporated in a Speed Vac (Savant Instruments, Nassau-Suffolk, NY).
The labeling reaction was performed by adding 3.5 μL of 12 mM BH (d_o-BH) or d4-BH (6 mM BH and 6 mM d4-BH when isotopologue labeling with tag mixture was done), and 3.5 μL of 80 mM EDC, in 0.01 M MES buffer at pH 6, to the dried HPLC collection vial, and then, after mixing, the sample was kept at room temperature for 3 hours.
The residual BH tag and EDC were removed with an UltraMicroSpin Column (The Nest Group, Southborough, MA) packed with 55 μL of propyl sulfonic acid silica, followed by evaporation and then redissolving in 5 μL of TEAA buffer (0.02 M at pH 7, 3% methanol, 3% ACN). The sample was injected into a trapping column (PepMap C18, 300 μm ID × 5 mm) on a column switching module of a Micro-LC system (Dionex, Sunnyvale, CA) at a flow rate of 7 μL/min with 20 mM TEAA buffer containing 1% ACN for 4 min, then 2 min at 14 μL/min. Switching was then done onto a capillary column (180 μm I.D × 150 mm), which was gradient eluted from 3% to 60 % ACN in 40 min at 2.2 μL/min. A droplet was collected onto a MALDI plate every 20 sec with a Probot Micro Fraction Collector (Dionex, Sunnyvale, CA).
CCA matrix (0.5 μl, 5 mg/mL in ACN: water, 50:50, v/v, with 2.5 mM of ammonium citrate, dibasic) was deposited on each dried spot, followed by air-drying for 5 min. For calibration, a reference compound (e.g. 1,N⁶-etheno dAMP subjected to BH-labeling) can be included in the CCA matrix solution. Analysis was done on a Voyager DE STR MALDI-TOF-MS or a Model 5800 MALDI-TOF/TOF-MS (AB SCIEX, Foster City, CA) in a negative, reflectron mode with a delay time of 150 ns. Each sample well was surveyed to find “sweet spot”, and then 400 laser pulses were averaged to generate a spectrum. MS/MS was performed with a medium pressure of air and a mass resolution window of 400 with the metastable-suppresor on.

Wang P., Fisher D., Rao A, & Giese R.W. (2012). Nontargeted Nucleotide Analysis Based on Benzoylhistamine Labeling-MALDI-TOF/TOF-MS: Discovery of Putative 6-Oxo-Thymine in DNA. Analytical Chemistry, 84(8), 3811-3819.

Publication 2012

Most recents protocols related to «Cinnamic acid»

Cinnamic Acid Promotes Hair Growth

To investigate the effects of cinnamic acid on hair growth, DP cells (5 × 10³ cells) and epithelial cells (5 × 10³ cells) were suspended in 0.2 mL advanced Dulbecco's Modified Eagle Medium/Nutrient Mixture F-12 (DMEM/F-12; Thermo Fisher Scientific) containing 2% (v/v) Matrigel (Corning Inc.) and seeded into the wells of a non-cell-adhesive round-bottom 96-well plate (Primesurface^® 96U plate; Sumitomo Bakelite Co., Ltd., Japan). DMEM/F-12 medium was supplemented with 10 μM cinnamic acid for 4–10 days after seeding. Then, 0.1 mL of the spent medium was replaced with fresh medium every 2 days. Hair sprout lengths were observed using an all-in-one fluorescence microscope (BZ-X810; Keyence).

Kageyama T., Seo J., Yan L, & Fukuda J. (2024). Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation. Scientific Reports, 14, 4709.

Publication 2024

Biofilm Inhibition by Cinnamic Acid

Not available on PMC !

The biofilm formation was evaluated in various clinical samples of Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus (pathogenic bacteria isolated from Ramadi Teaching hospitals) using a microtiter plate (MTP) assay. First, 200 μl of a 0.5 McFarland bacterial suspension was added to each well of a 96-well microtiter plate. After the bacterial culture was diluted and added to the wells, 20 μL of cinnamic acid solutions were added. The concentrations of the cinnamic acid solutions were half and one-quarter of these acids' minimum inhibitory concentrations (MICs). The plates were incubated for 24 hours at 37°C. After incubation, the plates were washed twice with phosphate-buffered saline to remove non-adherent cells, if any. The wells were then stained with a 0.1% v/ v crystal violet solution. After the dye was solubilized in 33% v/v acetic acid, the optical density (OD) of each well was measured at 630 nm using a microtiter plate reader (Tutar et al. 2016) . Each assay was performed thrice, and wells containing no cinnamic or gallic acids were used as positive controls for biofilm formation. This means that these wells were expected to form biofilms, and their OD readings were compared to the OD readings of the wells containing cinnamic or gallic acids. The calculation of the biofilm reduction percentage was carried out using the following formula : [(Ac -As) / Ac] * 100 ……..Eq. 1 Where Ac = OD630 value of the positive control wells; As = OD630 value of the wells treated with cinnamic acid (Shao et al. 2015) .

Almawla S.O.G., Dali L., Ragheb Y.M., Edan A.I., Ahmed M.M., Abdulkareem A.H., & Waheeb A.A. (2024). Antibacterial and antibiofilm activity of cinnamic acid against Multidrug-resistant bacteria isolated from Ramadi Teaching hospitals, Iraq. Journal of Applied and Natural Science, 16(1), 356-363.

Publication 2024

Cinnamic Acid Effects on DP Cell Culture

DP cells (2 × 10⁴ cells) were suspended in 0.5 mL DPCGM medium supplemented with 0, 50, 100, 500, 1000, or 2000 μg/mL Cinnamic acid (WAKO, Japan), and seeded into the wells of a 24-well cell culture plate (Corning Inc., Corning, NY, USA). Cells were counted using a cell counter (Chemometec, Denmark) after 3 min of trypsin–EDTA treatment. Gene expression in DP cells was assessed using real-time reverse transcription-polymerase chain reaction (RT-PCR) after 3 days of culture.

Publication 2024

HPLC Analysis of Polyphenolic Compounds

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Publication 2024

Metabolomic Profiling of Cinnamic Acid Derivatives

The raw MS data (wiff.scan files) were converted to MzXML files using ProteoWizard MSConvert^{74 (link)}. Peak picking and peak grouping were conducted by using R package XCMS v3.20.0^{75 (link)}. Annotation of adducts and calculating hypothetical masses for the group were performed with R package CAMERA (Collection of Algorithms of MEtabolite pRofile Annotation) v3.1-5^{76 (link)}. In the extracted ion features, only the variables with > 50% of nonzero measurement values in at least one group were kept. Identification of cinnamic acid and derivatives was performed by comparing high-accuracy m/z value using MS/MS spectra with an in-house cinnamic acid and derivatives database established with available standards.
After normalization for total peak area intensity, clustering analysis of metabolites were performed with R package ComplexHeatmap^{77 (link)}. A principal coordinates analysis (PCoA) of Bray-Curtis distances was performed using R package vegan, and a pairwise Adonis test and PERMANOVA (999 permutations) were performed using R package amplicon. Analysis of differential intensity of total peak areas was performed using Tukey’s HSD test. Features were visualized by using ggplot2.

Su P., Kang H., Peng Q., Wicaksono W.A., Berg G., Liu Z., Ma J., Zhang D., Cernava T, & Liu Y. (2024). Microbiome homeostasis on rice leaves is regulated by a precursor molecule of lignin biosynthesis. Nature Communications, 15, 23.

Publication 2024

Top products related to «Cinnamic acid»

Cinnamic acid by Merck Group

Sourced in United States, Germany, United Kingdom, China, Italy, Portugal, Switzerland, India, Sao Tome and Principe

Cinnamic acid is a naturally occurring organic compound. It is a white crystalline solid with a sweet, aromatic odor. Cinnamic acid is commonly used as a starting material in the synthesis of various organic compounds and as a chemical building block in the pharmaceutical and cosmetic industries.

Caffeic acid by Merck Group

Sourced in United States, Germany, Italy, France, Poland, Spain, China, United Kingdom, Australia, Sao Tome and Principe, Switzerland, India, Ireland, Canada, Macao, Brazil, Austria, Mexico, Czechia, Portugal

Caffeic acid is a phenolic compound commonly found in various plants. It serves as a laboratory standard for the identification and quantification of similar phenolic compounds using analytical techniques such as high-performance liquid chromatography (HPLC) and spectrophotometry.

Gallic acid by Merck Group

Sourced in United States, Germany, Italy, Spain, France, India, China, Poland, Australia, United Kingdom, Sao Tome and Principe, Brazil, Chile, Ireland, Canada, Singapore, Switzerland, Malaysia, Portugal, Mexico, Hungary, New Zealand, Belgium, Czechia, Macao, Hong Kong, Sweden, Argentina, Cameroon, Japan, Slovakia, Serbia

Gallic acid is a naturally occurring organic compound that can be used as a laboratory reagent. It is a white to light tan crystalline solid with the chemical formula C6H2(OH)3COOH. Gallic acid is commonly used in various analytical and research applications.

Ferulic acid by Merck Group

Sourced in United States, Germany, Italy, United Kingdom, Spain, China, France, Poland, Australia, Ireland, Malaysia, Canada, India, Switzerland, Sao Tome and Principe, Japan, Brazil, Denmark

Ferulic acid is a phenolic compound that can be found in various plant sources, including rice, wheat, oats, and vegetables. It is commonly used as a lab equipment product for research and analysis purposes. Ferulic acid has antioxidant properties and can be used in a variety of applications, such as the study of plant-based compounds and their potential health benefits.

P coumaric acid by Merck Group

Sourced in United States, Germany, Italy, Spain, France, China, Poland, United Kingdom, Sao Tome and Principe, Switzerland, Canada, Ireland, India, Australia, Japan, Macao, Portugal

P-coumaric acid is a naturally occurring phenolic compound that can be utilized as a reference standard or an analytical reagent in various laboratory settings. It is a white to off-white crystalline solid that is soluble in organic solvents. P-coumaric acid is commonly used as a standard in analytical techniques, such as high-performance liquid chromatography (HPLC) and spectrophotometric measurements, to quantify and characterize similar compounds in sample matrices.

Quercetin by Merck Group

Sourced in United States, Germany, Italy, India, Spain, United Kingdom, France, Poland, China, Sao Tome and Principe, Australia, Brazil, Macao, Switzerland, Canada, Chile, Japan, Singapore, Ireland, Mexico, Portugal, Sweden, Malaysia, Hungary

Quercetin is a natural compound found in various plants, including fruits and vegetables. It is a type of flavonoid with antioxidant properties. Quercetin is often used as a reference standard in analytical procedures and research applications.

Chlorogenic acid by Merck Group

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Chlorogenic acid is a compound found in various plants, including coffee beans. It is a type of polyphenol and is commonly used in laboratory settings for research purposes.

Trans cinnamic acid by Merck Group

Sourced in United States, Germany, Sao Tome and Principe, Italy, Australia

Trans-cinnamic acid is a naturally occurring organic compound that serves as a key intermediate in the production of various chemical compounds. It is characterized by its carboxylic acid functional group and a trans-configured alkene. Trans-cinnamic acid is utilized as a starting material or precursor in the synthesis of various pharmaceuticals, flavors, and fragrances.

Catechin by Merck Group

Sourced in United States, Germany, Italy, France, Australia, India, Spain, United Kingdom, China, Poland, Sao Tome and Principe, Japan, Portugal, Canada, Switzerland, Brazil, Malaysia, Singapore, Macao, Belgium, Ireland, Mexico, Hungary

Catechin is a natural polyphenolic compound found in various plants, including green tea. It functions as an antioxidant, with the ability to scavenge free radicals and protect cells from oxidative stress.

Vanillic acid by Merck Group

Sourced in United States, Germany, Italy, United Kingdom, Spain, China, France, Australia, Poland, India, Mexico, Singapore, Sao Tome and Principe, Canada

Vanillic acid is a chemical compound that is commonly used in laboratory settings. It is a white, crystalline solid with a characteristic vanilla-like odor. Vanillic acid is often used as a reference standard in analytical methods and as a precursor in the synthesis of other chemical compounds.

More about "Cinnamic acid"

Cinnamic acid is a naturally occurring organic compound found in various plants, including cinnamon, other aromatic herbs, and various other botanical sources.
It is a white crystalline substance with a distinctive cinnamony aroma.
Cinnamic acid has a diverse range of biological activities and is utilized in the synthesis of numerous pharmaceuticals, fragrances, and other chemical products.
Cinnamic acid plays a role in plant defense mechanisms and has been studied for its potential antioxidant, anti-inflammatory, and antimicrobial properties.
Research into the applications and effects of cinnamic acid, as well as related compounds like caffeic acid, gallic acid, ferulic acid, p-coumaric acid, quercetin, chlorogenic acid, trans-cinnamic acid, catechin, and vanillic acid, is an active area of scientific inquiry.
PubCompare.ai can help optimize cinnamic acid research by locating relevant protocols from literature, preprints, and patents, and leveraging AI-driven comparisons to identify the best protocols and products, enhancing reproducibility and accureacy in cinnamic acid studies.