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Ethylenediamine

Ethylenediamine is a colorless, flamma ble liquid with a pungent odor.
It is used as a building block in the synthesis of various organic compounds, including pharmaceuticals, pesticides, and industrial chemicals.
Ethylenediamine serves as a chelating agent, a corrosion inhibitor, and a curing agent for epoxy resins.
It can also be employed as a reagent in analytical chemistry and as a component in personal care products.
Ethylenediamine's diverse applications stem from its ability to form stable complexes with metal ions and its reactivity towards other functional groups.

Most cited protocols related to «Ethylenediamine»

1
Comprehensive Biomarker Profiling Protocol
Height and body weight were measured as described previously [26] (link), Sitting blood pressure was measured thrice over 10 min and the median value used in the statistical analysis. The status of smoking and drinking was self-reported using a questionnaire as described previously [27] , [28] (link). Two tubes (one containing ethylenediamine tetra-acetic acid (EDTA) and the other not containing an anticoagulant agent) were used for collecting blood samples after the patient had fasted. The collected samples were separated into plasma, serum and blood cells (including leukocytes) and stored at −80°C for the analysis of routine blood chemistry and DNA extraction. Samples were transported on dry ice at prearranged intervals to laboratories. We measured the serum concentration of total cholesterol, triglyceride, blood urea nitrogen (BUN), creatinine (Cr), LDL, HDL, uric acid and fasting glucose using equipment for chemical analysis (Dimension AR/AVL Clinical Chemistry System, Newark, NJ, USA) employed by the Clinical Laboratory Department of the First Affiliated Hospital of Xinjiang Medical University.
Xie X., Ma Y.T., Yang Y.N., Fu Z.Y., Li X.M., Huang D., Ma X., Chen B.D, & Liu F. (2010). Polymorphisms in the SAA1/2 Gene Are Associated with Carotid Intima Media Thickness in Healthy Han Chinese Subjects: The Cardiovascular Risk Survey. PLoS ONE, 5(11), e13997.
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Publication 2010
Acetic Acid Anticoagulants BLOOD Blood Cells Blood Chemical Analysis Blood Pressure Body Weight Cholesterol Clinical Laboratory Services Creatinine Dry Ice ethylenediamine Glucose Hematologic Tests Leukocytes Patients Plasma Serum Specimen Collection Tetragonopterus Triglycerides Urea Nitrogen, Blood Uric Acid
2
Surface Modification of Graphene Oxide for Cryo-EM

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Publication 2019
Amines Anabolism Biopharmaceuticals Epoxy Resins Ethanol Ethylenediamines Sulfoxide, Dimethyl
3
Subcultivating Intestinal Epithelial Cells

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Publication 2017
4
Plasma DNA Extraction Protocol
Whole blood (9 ml) was collected in routine ethylenediamine tetraacetic acid (EDTA) Vacutainer tubes (BD Biosciences, Heidelberg, Germany). To stabilize cell membranes and to impede cell lysis, 0.225 ml of a 10% neutral buffered solution containing formaldehyde (4% weight per volume) (Sigma-Aldrich, Vienna, Austria) was added immediately after blood withdrawal. Blood samples were gently inverted, stored at room temperature and further processed within 2 hr. Plasma was prepared according to Ref.22 (link). In brief, tubes were centrifuged at 200g for 10 min with the brake and acceleration powers set to zero, followed by a subsequent centrifugation step at 1600g for 10 min. The supernatant was collected, transferred to a new 15 ml tube and spun at 1600g for 10 min. The plasma was carefully aliquoted into new 2 ml Eppendorf tubes and stored at −80°C.
DNA was isolated from plasma samples using the QIAamp DNA Blood Mini Kit (Qiagen, Hilden, Germany) or the Qiagen Circulating Nucleic Acids Kit (CNA) (Qiagen, Hilden, Germany) according to the manufacturer's instructions. DNA was eluted in 30 μl of distilled water for Mini Kit extractions and in 100 µl for CNA Kit, respectively.
Heitzer E., Auer M., Hoffmann E.M., Pichler M., Gasch C., Ulz P., Lax S., Waldispuehl-Geigl J., Mauermann O., Mohan S., Pristauz G., Lackner C., Höfler G., Eisner F., Petru E., Sill H., Samonigg H., Pantel K., Riethdorf S., Bauernhofer T., Geigl J.B, & Speicher M.R. (2013). Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer. International Journal of Cancer. Journal International du Cancer, 133(2), 346-356.
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Publication 2013
Acceleration BLOOD Cell-Free Nucleic Acids Cells Centrifugation Edetic Acid Formalin Plasma Plasma Membrane
5
Preparation of Bovine Decellularized Extracellular Matrix

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Publication 2013
Acclimatization Acids Bone Matrix Bones Bos taurus Cancellous Bone Cells Chloroform Cytoplasmic Granules Edetic Acid Enzymes Freezing Lipids Methanol Penicillin V Powder Streptomycin Trypsin Vacuum

Most recents protocols related to «Ethylenediamine»

1
Orange Peel Fluorescence Intensity
Different dosages of ethylenediamine will greatly affect the fluorescence intensity of the system. The dosage of ethylenediamine was added as 1.00, 2.00, 3.00, 4.00, and 5.00 mL, 4.00 g of orange peel was added, and the reaction was carried out at 180 °C for 3 hours. The fluorescence intensity was measured.
Han L., Guo Y., Zhang H., Wang Z., Zhang F., Wang Y., Li X., Wang Y, & Ye J. (2024). Preparation of carbon quantum dot fluorescent probe from waste fruit peel and its use for the detection of dopamine. RSC Advances, 14(3), 1813-1821.
Publication 2024
2
Synthesis and Characterization of CD-Au Nanohybrid
Not available on PMC !
50 mL of 0.2 mg mL -1 carbon dot (CDs) aqueous colloidal dispersion was diluted with 50 mL of ultrapure water and degassed at 0 °C for 1 h with Ar flow in a two-neck round bottom flask before the pH was modified to 4 by adding 0.1 M HCl. As the next step, 159.6 mg of (N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride) -EDC hydrochloride, and subsequently, 143.8 mg of N-hydroxysuccinimide were added. The reaction mixture was magnetically stirred for 1 h in the ice bath. Ethylenediamine (5.56 mL) was poured, and the reaction was continued for 1 h under ice and overnight at room temperature, maintaining the inert atmosphere (Fig. 1). The reaction mixture was purified by dialysis (MWCO = 14 kDa) using deionized water for two days, changing the water every 2-8 h obtaining a light-yellow CD-ethylenediamine (CD-E) dispersion of about 0.1 mg mL -1 . The concentration of CD-E was quantified by weighing the residue obtained from solvent evaporation. ) was added to an aqueous dispersion of CD-ethylenediamine (100 mL, 0.1 mg mL -1 ) under vigorous stirring. The mixture was irradiated with a blue (420-430 nm) LED for 310 min and left under stirring overnight in the darkness (Fig. 2). The crude was purified by filtration to remove larger aggregates and subsequent centrifugation (1 h, 8500 RCF). The supernatant was discarded because only unreacted CDs were present according to UV/Vis absorption and fluorescence spectra, while the precipitate was collected, washed two times with ultrapure water, and sonicated for 2 h. CD-Au nanohybrid was stored at RT in ultrapure water dispersion, appreciating at least 2 months of stability, and was characterized without further purification. All the reaction steps and the reaction kinetics were monitored via UV/Vis absorption spectroscopy.
Nocito G., Zribi R., Chelly M., Pulvirenti L., Nicotra G., Bongiorno C., Arrigo A., Fazio B., Neri G., Nastasi F, & Conoci S. (2024). Photochemical synthesis, characterization, and electrochemical sensing properties of CD-AuNP nanohybrids. Nanoscale, 16(7).
Publication 2024
3
Synthesis of Fluorinated Schiff Base Ligand
Not available on PMC !
532 µmol (145 mg) meso-1,2-bis(3-methoxyphenyl)ethylenediamine (II) and 1.27 mmol (178 mg) of 5-fluorosalicylaldehyde; Yield 99% (0.527 mmol, 272 mg); melting point (mp): 159 °C. 1 H NMR (400 MHz, Chloroform-d) δ 12.81 (s, 2H, OH), 8.03 (s, 2H, HC=N), 7.22 (t, J = 7.9 Hz, 2H), 7.01 (ddd, J = 9.1, 8.1, 3.1 Hz, 2H), 6.92 to 6.84 (m, 4H), 6.84 to 6.75 (m, 6H), 4.70 (s, 2H, CH), 3.73 (s, 6H, OCH 3 ). 13
Bernkop-Schnürch A.D., Huber K., Clauser A., Cziferszky M., Leitner D., Talasz H., Hermann M., Hohloch S., Gust R, & Kircher B. (2024). Design, synthesis, and biological evaluation of novel halogenated chlorido[N,N'-bis(salicylidene)-1,2-bis(3-methoxyphenyl)ethylenediamine]iron(III) complexes as anticancer agents. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.
Publication 2024
4
Synthesis of meso-1,2-bis(3-methoxyphenyl)ethylenediamine
Not available on PMC !
Synthesis of meso-1,2-bis(3-methoxyphenyl)ethylenediamine (II) (step 1) 6.193 mmol (1.513 g) of meso-1,2-bis(2-hydroxyphenyl)ethylenediamine (I) and 14.21 mmol (1.935 g) 3methoxybenzaldehyde were stirred in acetonitrile anhydrous (MeCN) under reflux for 12 h to obtain after recrystallization a colourless powder. Yield: 5.129 mmol (1.397 g), 93%. This intermediate was suspended in 50 ml MeCN and 12.5 ml 37% HCl (ratio 4:1) and stirred under reflux for 5 h. After cooling overnight, the formed precipitate was collected via filtration and washed with MeCN and dried in vacuo. Yield: 3.43 mmol (0.935 g), 88%, colourless powder.
Bernkop-Schnürch A.D., Huber K., Clauser A., Cziferszky M., Leitner D., Talasz H., Hermann M., Hohloch S., Gust R, & Kircher B. (2024). Design, synthesis, and biological evaluation of novel halogenated chlorido[N,N'-bis(salicylidene)-1,2-bis(3-methoxyphenyl)ethylenediamine]iron(III) complexes as anticancer agents. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.
Publication 2024
5
Synthesis and Characterization of Iron(III) Complexes
Not available on PMC !
Briefly, a mixture of 1 equiv. substituted meso-1,2-bis(3-methoxyphenyl)ethylenediamine ligands L1-L3 and 1 equiv. iron(III) chloride anhydrous was dissolved in ethanol anhydrous (EtOH, 7 mL). Quickly the solution turned dark and the reaction was allowed to complete for 2 h under reflux conditions. The precipitate was recrystallized in EtOH and dried in vacuo. All synthesized complexes were characterized and the purity was verified based on HPLC, confirming purity > 99% (Table S2). The spectra and the HPLC chromatograms are given in the supplementary information (Figures S16-S28).
Bernkop-Schnürch A.D., Huber K., Clauser A., Cziferszky M., Leitner D., Talasz H., Hermann M., Hohloch S., Gust R, & Kircher B. (2024). Design, synthesis, and biological evaluation of novel halogenated chlorido[N,N'-bis(salicylidene)-1,2-bis(3-methoxyphenyl)ethylenediamine]iron(III) complexes as anticancer agents. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.
Publication 2024

Top products related to «Ethylenediamine»

1
Ethylenediamine by Merck Group
Sourced in United States, Germany, United Kingdom, Canada, Spain, Italy, Switzerland, China, Czechia, India
Ethylenediamine is a colorless, flammable liquid with a characteristic ammonia-like odor. It is commonly used as a building block for the synthesis of various chemical compounds in laboratory settings.
2
Fetal bovine serum (fbs) by Thermo Fisher Scientific
Sourced in United States, China, United Kingdom, Germany, Australia, Japan, Canada, Italy, France, Switzerland, New Zealand, Brazil, Belgium, India, Spain, Israel, Austria, Poland, Ireland, Sweden, Macao, Netherlands, Denmark, Cameroon, Singapore, Portugal, Argentina, Holy See (Vatican City State), Morocco, Uruguay, Mexico, Thailand, Sao Tome and Principe, Hungary, Panama, Hong Kong, Norway, United Arab Emirates, Czechia, Russian Federation, Chile, Moldova, Republic of, Gabon, Palestine, State of, Saudi Arabia, Senegal
Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
3
Sulfanilamide by Merck Group
Sourced in United States, Germany, India, Sao Tome and Principe, United Kingdom, Japan, Portugal, Australia, Switzerland, Spain
Sulfanilamide is a chemical compound used in laboratory settings. It is a white, crystalline powder with a melting point of 165-167°C. Sulfanilamide is a sulfonamide drug that has been used as a bacteriostatic agent. Its core function is to inhibit the growth and reproduction of certain bacteria.
4
N 1 naphthyl ethylenediamine dihydrochloride by Merck Group
Sourced in United States, Germany, India, China
N-(1-naphthyl) ethylenediamine dihydrochloride is a chemical compound used as a reagent in various analytical and laboratory applications. It functions as a colorimetric agent, producing a colored reaction when combined with certain analytes. The core purpose of this product is to facilitate specific detection and quantification procedures in a laboratory setting.
5
Dimethyl sulfoxide (dmso) by Merck Group
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DMSO is a versatile organic solvent commonly used in laboratory settings. It has a high boiling point, low viscosity, and the ability to dissolve a wide range of polar and non-polar compounds. DMSO's core function is as a solvent, allowing for the effective dissolution and handling of various chemical substances during research and experimentation.
6
Bovine serum albumin (bsa) by Merck Group
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Bovine serum albumin (BSA) is a common laboratory reagent derived from bovine blood plasma. It is a protein that serves as a stabilizer and blocking agent in various biochemical and immunological applications. BSA is widely used to maintain the activity and solubility of enzymes, proteins, and other biomolecules in experimental settings.
7
Ethylenediaminetetraacetic acid by Merck Group
Sourced in United States, Germany, India, United Kingdom, Italy, Australia, Spain, Sao Tome and Principe, Switzerland, France, China, Portugal, Macao, Japan, Czechia, Denmark
Ethylenediaminetetraacetic acid (EDTA) is a chemical compound commonly used in scientific and laboratory settings. It functions as a chelating agent, capable of forming stable complexes with metal ions. EDTA is primarily used for the analysis and separation of various metal ions in samples.
8
Hydrochloric acid (hcl) by Merck Group
Sourced in Germany, United States, United Kingdom, India, Italy, France, Spain, Australia, China, Poland, Switzerland, Canada, Ireland, Japan, Singapore, Sao Tome and Principe, Malaysia, Brazil, Hungary, Chile, Belgium, Denmark, Macao, Mexico, Sweden, Indonesia, Romania, Czechia, Egypt, Austria, Portugal, Netherlands, Greece, Panama, Kenya, Finland, Israel, Hong Kong, New Zealand, Norway
Hydrochloric acid is a commonly used laboratory reagent. It is a clear, colorless, and highly corrosive liquid with a pungent odor. Hydrochloric acid is an aqueous solution of hydrogen chloride gas.
9
Sodium hydroxide (naoh) by Merck Group
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Sodium hydroxide is a chemical compound with the formula NaOH. It is a white, odorless, crystalline solid that is highly soluble in water and is a strong base. It is commonly used in various laboratory applications as a reagent.
10
Phosphoric acid by Merck Group
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Phosphoric acid is a chemical compound with the formula H3PO4. It is a colorless, odorless, and viscous liquid that is commonly used in various industrial and laboratory applications.

More about "Ethylenediamine"

Ethylenediamine, also known as 1,2-diaminoethane or EDA, is a colorless, flammable liquid with a pungent odor.
It is a versatile chemical used in the synthesis of various organic compounds, including pharmaceuticals, pesticides, and industrial chemicals.
Ethylenediamine serves as a chelating agent, a corrosion inhibitor, and a curing agent for epoxy resins.
It can also be employed as a reagent in analytical chemistry and as a component in personal care products.
The diverse applications of Ethylenediamine stem from its ability to form stable complexes with metal ions and its reactivity towards other functional groups.
It is commonly used in the production of pharmaceuticals, such as Sulfanilamide, a sulfonamide antibiotic, and N-(1-naphthyl) ethylenediamine dihydrochloride, a reagent used in analytical chemistry.
Ethylenediamine is also utilized in the preparation of various industrial chemicals, including DMSO (Dimethyl sulfoxide), a widely used solvent, and Ethylenediaminetetraacetic acid (EDTA), a chelating agent.
Additionally, it can be found in personal care products, such as Bovine serum albumin (BSA), which is used in cell culture media.
The handling and storage of Ethylenediamine require caution, as it is a flammable liquid.
Proper safety protocols, including the use of personal protective equipment (PPE) and proper ventilation, should be followed when working with this chemical.
Its reactivity with acids, such as Hydrochloric acid and Phosphoric acid, as well as its interactions with bases, like Sodium hydroxide, should also be considered when using Ethylenediamine in research or industrial applications.