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Gadolinium DTPA

Gadolinium DTPA is a contrast agent used in magnetic resonance imaging (MRI) to enhance the visualization of various tissues and pathologies.
It consists of the gadolinium ion chelated with the diethylenetriaminepentaacetic acid (DTPA) ligand.
Gadolinium DTPA is widely utilized in clinical practice to assess a range of conditions, such as brain lesions, spinal cord abnormalities, and vascular diseases.
Its ability to alter the relaxation times of protons in the body allows for improved contrast and detai in MRI scans.
Researchers studying Gadolinium DTPA can leverge PubCompare.ai to optimize their research protocols, locaet relevant literature, and ensure reproducibility and accuracy in their work.

Most cited protocols related to «Gadolinium DTPA»

1
Multiparametric Evaluation of Cerebral Hemodynamics
Cited 32 times
MR experiments (3 Tesla, Siemens Medical Solutions, Erlangen, Germany) were performed on a total of 39 healthy subjects (age 31±7 years, range 19–48 years, 23 males and 16 females). The protocol was approved by Institutional Review Board. Informed written consent was obtained for each participant. The body coil was used for RF transmission and a head coil was used for receiving. Foam paddings were used to stabilize the head to minimize motion. The subjects were instructed not to fall asleep during the experiments (verified after the session), as the cerebral blood flow and venous oxygenation may change during sleep. Four effective TEs were used: 0ms, 40ms, 80ms and 160ms, corresponding to 0, 4, 8 and 16 refocusing pulses in the T2-preparation (τCPMG=10ms). Other Imaging parameters: FOV=230mm, matrix=64×64, single-shot EPI, slice thickness=5mm, TR=8000ms, TE=19ms, TI=1200ms, repetition=4, thickness of labeling slab = 50 mm, gap between labeling slab and imaging slice = 25 mm, scan duration 4 minutes and 16 seconds.
In a sub-group of healthy subjects (n=6), the intra-session reproducibility was evaluated by performing five TRUST MRI scans at approximately 10 minute intervals. The same slice locations and imaging parameters were used for the five scans.
In a sub-group of healthy subjects (n=5), TR dependence of the measurement was investigated by performing TRUST MRI using TR values of 1.5 seconds to 8 seconds at 0.5 second intervals (14 different TR values). All other parameters were identical as specified above. The durations for the scans depended on TR and varied from 48 seconds to 4 minutes and 16 seconds. In one subject, the TI dependence was investigated (with fixed TR) and the TI values varied from 200ms to 2600ms (13 different TI values). All other parameters were identical as specified above.
In two healthy subjects, hypercapnia challenge (by breathing through a plastic tube with 600ml of volume, thereby increasing the dead-space (25 (link))) was induced and TRUST MRI was performed before, during, and after the challenge. End-tidal CO2 (EtCO2) was monitored throughout the experiment and was compared to MRI results.
In three healthy subjects, TRUST MRI was performed before and after 200mg caffeine tablet ingestion (26 (link)). The pre-caffeine scan was first performed. Then, while still inside the head coil, the subject was instructed to open his or her mouth for the researcher to place one tablet inside, and a small amount of water was administered via a straw to assist with swallowing. The MRI table was then repositioned to the iso-center. Twenty minutes later, the post-caffeine TRUST scan was performed. During the twenty minute waiting time, other anatomical scans (e.g. T1-weigthed anatomical imaging) were performed.
In three subjects, TRUST MRI was performed before and after the intravenous administration of Gd-DTPA contrast agent (Magnevist, Berlex Laboratories, Wayne, NY) at standard dosage (0.1 mmol/kg). The post-contrast TRUST was performed approximately 6 minutes after the injection of the contrast agent so that the agent concentration remained relatively constant for the duration of the TRUST scan.
Lu H, & Ge Y. (2008). Quantitative evaluation of oxygenation in venous vessels using T2-Relaxation-Under-Spin-Tagging MRI. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 60(2), 357-363.
Publication 2008
Caffeine Cell Respiration Cerebrovascular Circulation Contrast Media Ethics Committees, Research Females Gadolinium DTPA Head Healthy Volunteers Human Body Intravenous Infusion Magnevist Males MRI Scans Neoplasm Metastasis Oral Cavity Pulses Radionuclide Imaging Sleep Tablet Transmission, Communicable Disease Veins
2
Dynamic Contrast-Enhanced Liver MRI Protocol
Cited 19 times
DCE liver MRI was performed in six healthy volunteers (age 34.5±5.2 years) and seven patients (age 51±8.4 years) in axial orientation during free breathing using whole-body 3-T or 1.5-T scanners (MAGNETOM Verio / Avanto, Siemens AG, Erlangen, Germany) with a combination of body-matrix and spine coil elements with 12 channels in total. Data acquisition was initiated simultaneously with intravenous injection of 10 ml of gadopentate dimeglumine (Gd-DTPA) (Magnevist, Bayer Healthcare, Leverkusen) followed by a 20-ml saline flush, both injected at a rate of 2 ml/second. A radial stack-of-stars 3D Fast Low Angle SHot (FLASH) pulse sequence with golden-angle ordering was employed for the data acquisitions. Two-fold readout oversampling was applied to avoid spurious aliasing along the spokes. All partitions corresponding to one radial angle were acquired sequentially before moving to the next angle. The ordering scheme along kz was switched between linear (from kz=-kzmax/2 to kz=+kzmax/2) and centric out (starting at kz=0) depending on the number of slices, as done in most of the modern 3D gradient echo (GRE) sequences. Frequency-selective fat suppression was used and 60 initial calibration lines were acquired to correct system-dependent gradient-delay errors as described in (38 ). Relevant imaging parameters are listed in Table 1.
Feng L., Grimm R., Block K.T., Chandarana H., Kim S., Xu J., Axel L., Sodickson D.K, & Otazo R. (2013). Golden-Angle Radial Sparse Parallel MRI: Combination of Compressed Sensing, Parallel Imaging, and Golden-Angle Radial Sampling for Fast and Flexible Dynamic Volumetric MRI. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 72(3), 707-717.
Publication 2013
ECHO protocol Flushing Gadolinium DTPA Healthy Volunteers Human Body Liver Magnevist Patients Saline Solution Stars, Celestial Vertebral Column
3
Quantifying Myocardial Extracellular Volume with MRI
Cited 14 times
The ECV in the myocardium may be estimated from the concentration of extracellular contrast agent in the myocardium relative to the blood in a dynamic steady state [7 (link),9 (link),13 (link)].
ECV=1−hematocrit1T1myopost−1T1myopre1T1bloodpost−1T1bloodpre
since the change in relaxation rate ΔR1 (where R1 = 1/T1) between pre and post contrast is directly proportional to the Gd-DTPA concentration, ΔR1 = γ [Gd-DTPA] (γ = 4.5 L mmol-1 sec-1). A dynamic steady state exists for tissues which have a contrast exchange rate with the blood which is faster than the net clearance of contrast from the blood [7 (link)]. A dynamic steady state between the plasma and interstitium may be achieved by slow intravenous infusion [3 (link),9 (link)], or by imaging 15 min following an intravenous bolus administration [12 (link),13 (link)] for normally perfused myocardium, although 15 min may not be adequate for recently infarcted myocardium [16 (link)]. The bolus method was used in this study since it fits well with clinical workflow and permits conventional late enhancement imaging at the desired dose. The ECV formula (Eq [1 ]) implies that our myocardial ECV measurements include both the intra- and extravascular space, and is related to the estimate of extracellular extravascular volume fraction (Ve) [8 (link),12 (link)] which includes additional constant factors. The factor (1-hematocrit), which varies between individuals, represents the blood volume of distribution (blood ECV) and converts the equation from a partition coefficient calculation to a myocardial ECV.
Kellman P., Wilson J.R., Xue H., Ugander M, & Arai A.E. (2012). Extracellular volume fraction mapping in the myocardium, part 1: evaluation of an automated method. Journal of Cardiovascular Magnetic Resonance, 14(1), 63.
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Publication 2012
BLOOD Blood Volume Fibrinogen Gadolinium DTPA Intravenous Infusion Myocardium Plasma Seizures Tissues Volumes, Packed Erythrocyte
4
Cardiac T1 Mapping with Motion Correction
Cited 14 times
Imaging experiments were performed on 1.5T clinical MRI systems (MAGNETOM Espree and MAGNETOM Avanto, Siemens AG Healthcare Sector, Erlangen, Germany) equipped with 32 receiver channels. All subjects were scanned at the National Heart, Lung and Blood Institute, Bethesda, Maryland, USA. This study was approved by the local Institutional Review Board, and written informed consent was given by all participants.
A total of 45 patients (23 men, 22 women; mean age 47.1±15.9 years) were imaged both before and after contrast injection. Typical sequence parameters are as following: inversion recovery prepared MOLLI with balanced SSFP readout, TR=2.4/TE=1.05ms, acquired matrix 192×126, reconstructed matrix size 192×144, flip angle 35°, in-plane spatial resolution 1.9×2.1mm2, rectangular FOV 360×270mm2, slice thickness 6mm, bandwidth 1000 Hz/pixel. 8 images were acquired with 11 heart beats using 2 inversions. All acquisitions were ECG-gated and breath-held.
For every patient, the MOLLI imaging was performed for at least 2 slices (mid-ventricular short axis and four chamber long axis views) for both pre- and post-contrast. The post-contrast acquisition was performed at approximated 15-20 minutes following the intravenous injection of Gd-DTPA at 0.15 mmol/kg dose. The entire data cohort consists of 180 MOLLI series (90/90 pre/post-contrast, 95/85 short/long axis).
The proposed workflow was implemented using C++. All computation was performed on a 64bit Window 7 workstation containing two quad-core Intel Xeon E5620 2.4GHz processers and 24GB RAM. Typical processing time of PSIR-MOCO and fitting was less than 5 seconds per slice, including initial motion correction, background phase removal, MOLLI image registration and pixel-wise PSIR T1 fitting. The computational time is measured by recording the processing time per MOLLI series and computing the mean and standard deviation for all series.
Xue H., Greiser A., Zuehlsdorff S., Jolly M.P., Guehring J., Arai A.E, & Kellman P. (2012). Phase-Sensitive Inversion Recovery for Myocardial T1 Mapping with Motion Correction and Parametric Fitting. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 69(5), 1408-1420.
Publication 2012
BLOOD Epistropheus Ethics Committees, Research Gadolinium DTPA Heart Heart Ventricle Inversion, Chromosome Lung Neoplasm Metastasis Patients Woman
5
Quantifying Cartilage Glycosaminoglycan via dGEMRIC
Cited 10 times
Several series of NMR spectroscopy experiments were performed to determine the relaxivity of Gd(DTPA)2− in solutions of skim-milk powder at the concentrations of 0%–40%. As discussed in several reports in literature (13 (link),33 (link)), these concentrations cover the approximate range of the macromolecular contents in most biological tissues (the solid content in cartilage is about 20%–35% (34 (link),35 (link))). R-values of 4.2 (mM sec)−1 was found in our experiment for saline at 7T and 25°C, which agrees with the relaxivity values found in literature (14 (link),29 (link),30 (link),33 (link)).
The μMRI T1-GAG imaging followed the well-documented dGEMRIC procedure in the literature (10 (link),11 (link),29 (link)–31 (link)). Briefly summarized, each cartilage block was T1-imaged before (T1before) and after (T1after) a 10-hour immersion in 1 mM solution of a commercially available Gd(DTPA)2− contrast agent (Magnevist, Berlex, NJ) at the room temperature ([H11015]25°C). The T1 im ages were converted to the Gd(DTPA)2− concentration image of cartilage and subsequently to the GAG concentration image of cartilage (30 (link)).
The μMRI experiments were performed using a Bruker AVANCE II MRI console interfaced to a 7T/89 mm superconducting magnet, commercial microimaging accessory, and a home-built 4-mm solenoid coil. The tissue block was placed in the magnet at the magic angle, which minimizes the influence of the dipolar interactions (32 (link)). The echo time (TE) of the imaging sequence was 8.6 msec and the repetition time (TR) of the imaging experiment was 1.5 and 0.5 seconds for the before- and after-soaking experiments, respectively. The 1-mm-thick imaging slice was transversely located in the middle of the 10-mm-long specimen. The 2D in-plane pixel size was 13 μm. The measurement of 2D T1 images used the inversion-recovery pulse sequence with five inversion points (for the T1before, they were 0, 0.4, 1.1, 2.2, 4.0 sec; for the T1after, they were 0, 0.1, 0.3, 0.5, 1 sec), which allowed the calculation of T1 relaxation in the tissue through a single exponential equation on a pixel-by-pixel basis. (To save time, the repetition time TR in μMRI was less than 5T1. In this case, we used a modified T1 fitting function, Y = A(1 – B exp (-t/T1), where B is less than 2 when TR [H11021] 5T1.)
Xia Y., Zheng S, & Bidthanapally A. (2008). Depth-Dependent Profiles of Glycosaminoglycans in Articular Cartilage by μMRI and Histochemistry. Journal of magnetic resonance imaging : JMRI, 28(1), 151-157.
Publication 2008
A-A-1 antibiotic Biopharmaceuticals Cartilage Contrast Media ECHO protocol Gadolinium DTPA Magnevist Milk Neoplasm Metastasis Powder Pulse Rate Saline Solution Sequence Inversion Spectroscopy, Nuclear Magnetic Resonance Submersion Tissues

Most recents protocols related to «Gadolinium DTPA»

1
Multimodal Imaging Protocol for Chest Assessment
The examination was performed using a 3.0 T magnetic resonance scanner (Skyra; Siemens AG, Erlangen, Germany), which used a dedicated 16-channel phased-array coil. Patients underwent breathing training prior to examination to reduce respiratory motion artifacts. The following acquisition parameters were applied: coronal T2WI half-Fourier acquisition single-shot turbo spin echo (HASTE): rotation time (TR), 1,400 ms; echo time (TE), 87 ms; field of view (FOV), 400 mm × 400 mm; FOV, 1.3×1.3; slice thickness, 5 mm; slices, 24. Axial T2WI BLADE [which is also named periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER)]: TR, 3,000 ms; TE, 87 ms; FOV, 400 mm × 400 mm; FOV, 1.3×1.3; slice thickness, 5 mm; slices, 24. Axial T1WI three-dimensional volumetric interpolated breath-hold examination (VIBE-3D): TR, 4.11 ms; TE, 1.22 ms; FOV, 420 mm × 420 mm; FOV, 1.3×1.3; slice thickness, 3.5 mm. diffusion-weighted imaging (DWI): b value, 50,800 s/mm2; TR, 5,600 ms; TE, 72 ms; FOV, 400 mm × 400 mm; FOV, 1.6×1.6; slice thickness, 5 mm; and slices, 24. A dose of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) [Magnevist; 0.1 mmol/kg (0.2 mL/kg)] was injected as a quick bolus into the cubital vein at a rate of 3.0 mL/s by using a double-barrel high-pressure syringe. Allergy testing was performed before contrast injection to ensure patient safety. Radiomic features were extracted from chest axial T2WI.
The CT images were scanned using Toshiba (Tokyo, Japan), Philips (Amsterdam, Netherlands), and Siemens CT scanners. The default values of the scanners included tube voltage 120 kV and tube current 110–240 mA. After the real-time dynamic dose mapper was turned on, the relevant parameters included: collimation, 192 mm × 0.6 mm; TR, 0.25 s; pitch, 0.9; and slice thickness, 5 mm. The patient was asked to take a supine position, with both upper limbs naturally raised. The head was advanced first, and routine chest scan was performed at the end of the deep inspiration. The scan ranged from the thoracic inlet to the level 5 cm below the costophrenic angle. All CT images were reviewed with the lung window [window width, 1,500 Hounsfield units (HU); window level, −500 HU] and the mediastinal window (window width, 400 HU; window level, 45 HU), with the reconstructed slice thickness being 1 mm.
Yang M., Shi L., Huang T., Li G., Shao H., Shen Y., Zhu J, & Ni B. (2023). Value of contrast-enhanced magnetic resonance imaging-T2WI-based radiomic features in distinguishing lung adenocarcinoma from lung squamous cell carcinoma with solid components >8 mm. Journal of Thoracic Disease, 15(2), 635-648.
Publication 2023
Allergic Reaction CAT SCANNERS X RAY Chest Diffusion ECHO protocol Forearm Gadolinium DTPA Head Inhalation Lung Magnevist Mediastinum Nuclear Magnetic Resonance Patients Patient Safety Pressure Radionuclide Imaging Reconstructive Surgical Procedures Respiratory Rate Syringes Upper Extremity Veins
2
Dynamic Contrast-Enhanced MRI Protocol
MRI images were acquired with a 3.0 Tesla scanner (primary cohort: Signa HDxt or Discovery MR750; validation cohort: Signa HDxt, both from GE, Waukesha, WI, USA). Detailed MRI parameters are provided in supplemental Appendix S1. Dynamic contrast-enhanced scans were collected in the arterial phase (AP), portal venous phase (PVP), and equilibration phase (EP) at 14-20 s, 45-60 s, and 150-180 s, respectively, after injecting 0.1 mmol/kg Gd-DTPA.
Yang L., Wang M., Zhu Y., Zhang J., Pan J., Zhao Y., Sun K, & Chen F. (2023). Corona enhancement combined with microvascular invasion for prognosis prediction of macrotrabecular-massive hepatocellular carcinoma subtype. Frontiers in Oncology, 13, 1138848.
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Publication 2023
Arteries Gadolinium DTPA Radionuclide Imaging Veins, Portal
3
Multimodal Brain MRI Protocol

Protocol full text hidden due to copyright restrictions

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Publication 2023
Brain ECHO protocol Gadolinium Gadolinium DTPA Pentetic Acid Radionuclide Imaging
4
Spinal Cord Gd-DTPA Clearance Dynamics
The SD rats fasted for 12 h, drank water, and were in the prone position. Spontaneous breathing was maintained under sevoflurane inhalation anesthesia, with sevoflurane 2 l/min + oxygen 2 l/min inhalations. The body temperature was kept at 36.5–37.5 °C during imaging. All imaging protocols were performed on a 3.0 T MRI instrument (750Discover, General Electric Company, GE) and the animal special coil (eight-channel rat coil for GE). After scanning the basic value of the rat spinal cord, 25 μl 7.5% Magnevist (Gd-DTPA, Gadolinium-diethylenetriamine Penta-acetic acid, 469. 01 mg/ml, MW 938 Da, Bayer, Leverkusen, Germany) was slowly injected into the subarachnoid space of rats at L4–5 spaces in 5 min. After the injection, the puncture needle stayed in position for 3 min. Then, the scan was performed immediately. Scanning was performed before intrathecal injection of Gd-DTPA and 15, 30, 60, 90, 120, 150, 180, and 300 min after Gd-DTPA injection. During the absence of a scan, the rats were allowed to wake up, drank water freely, and were kept warm. The signal value was measured by the RadiAnt DICOM software (64bit, Version 2021.1, Medixant, Poznan, Poland). The spinal clearance rate equals the spinal cord signal difference (peak value minus 6th-hour signal intensity) divided by time.
Xu C., Wang F., Su C., Guo X., Li J, & Lin J. (2023). Restoration of aquaporin-4 polarization in the spinal glymphatic system by metformin in rats with painful diabetic neuropathy. Neuroreport, 34(3), 190-197.
Publication 2023
Acetic Acid Anesthesia, Inhalation Animals Body Temperature diethylenetriamine Electricity Gadolinium Gadolinium DTPA Inhalation Intrathecal Injection Magnevist Metabolic Clearance Rate Needles Oxygen Punctures Radionuclide Imaging Rattus Sevoflurane Spinal Cord Subarachnoid Space Tetranitrate, Pentaerythritol
5
Multimodal Imaging Evaluation of Paranasal Sinus Disorders
CT examinations were carried out using GE Light speed 16-slice and Siemens SOMATOM Definition 40-slice spiral CT scanners. Axial and coronal plain scanning and enhanced axial venous scanning were performed. Scanning parameters: tube current: 300mA; tube voltage: 120kV; matrix: 512x512; layer thickness: 3mm; window width: 250HU; and window level: 50HU. MR examinations were conducted using Siemens 1.5T, GE 3.0T magnetic resonance scanners, and quadrature head coil. Axial and coronal plain scanning, and enhanced axial, coronal and sagittal scanning were performed. Scanning parameters: T1WI: TR=230, TE=2.30; T2WI: TR=2800, TE=82.12; STIR sequences in coronal positions: TR=3200, TE=2.70; matrix: 256x256, layer thickness: 4mm, and interval: 1mm. Contrast-enhanced CT and MR scanning were respectively administered with the contrast agents of non-ionic iodine (ioversol, iohexol, dosage of 1.5ml/kg, flow rate of 3ml/s) and Gd-DTPA (dosage of 0.1mmol/kg, flow rate of 2ml/s) intravenously injected through the cubital vein with high-pressure syringe. The scanning range of CT and MR: the axial scanning was from the upper edge of the frontal sinus to the lower edge of the second cervical vertebra, while the coronal scanning was from the frontal sinus to the posterior edge of the sphenoid sinus, and the sagittal scanning covered the whole nasal cavity and paranasal sinuses.
Xiang J.Y., Huang X.S., Feng N., Zheng X.Z., Rao Q.P., Xue L.M., Ma L.Y., Chen Y, & Xu J.X. (2023). A diagnostic scoring model of ENKTCL in the nose-Waldeyer’s ring based on logistic regression: Differential diagnosis from DLBCL. Frontiers in Oncology, 13, 1065440.
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Publication 2023
CAT SCANNERS X RAY Contrast Media Epistropheus Frontal Sinus Gadolinium DTPA Head Iodine Iohexol ioversol Light Nasal Cavity Physical Examination Pressure Sinuses, Nasal Sphenoid Sinus Syringes Veins

Top products related to «Gadolinium DTPA»

1
Magnevist by Bayer
Sourced in Germany, United States, Japan, China, United Kingdom, Jersey, Canada, Ireland
Magnevist is a gadolinium-based contrast agent used in magnetic resonance imaging (MRI) procedures. It is designed to enhance the visualization of internal body structures and improve the diagnostic capabilities of MRI scans.
2
Gd dtpa by Bayer
Sourced in Germany
Gd-DTPA is a paramagnetic contrast agent used in magnetic resonance imaging (MRI) procedures. It contains the element gadolinium (Gd) chelated with the organic compound diethylenetriaminepentaacetic acid (DTPA). Gd-DTPA enhances the contrast of images in MRI scans by altering the magnetic properties of nearby water molecules, allowing for improved visualization of tissues and structures within the body.
3
Omniscan by GE Healthcare
Sourced in United States, Ireland, United Kingdom, Germany, China, Norway, France
Omniscan is a contrast agent used in magnetic resonance imaging (MRI) procedures. It is designed to enhance the visibility of certain structures or abnormalities within the body during the imaging process. Omniscan is administered intravenously prior to the MRI scan.
4
Discovery mr750 by GE Healthcare
Sourced in United States, Germany, United Kingdom, Netherlands
The Discovery MR750 is a magnetic resonance imaging (MRI) system developed by GE Healthcare. It is designed to provide high-quality imaging for a variety of clinical applications.
5
Gadovist by Bayer
Sourced in Germany, United States, Japan, Canada, Switzerland, United Kingdom, France, Spain
Gadovist is a contrast agent used in magnetic resonance imaging (MRI) procedures. It contains the active ingredient gadobutrol, which enhances the visibility of certain structures within the body during the MRI scan.
6
Magnetom avanto by Siemens
Sourced in Germany, United States, France
The Magnetom Avanto is a magnetic resonance imaging (MRI) system developed by Siemens. It is designed to provide high-quality imaging for a variety of clinical applications. The Magnetom Avanto utilizes a strong magnetic field and radio waves to generate detailed images of the body's internal structures.
7
Signa hdxt by GE Healthcare
Sourced in United States, United Kingdom, Germany, Japan, France
The Signa HDxt is a magnetic resonance imaging (MRI) system developed by GE Healthcare. It is designed to provide high-quality, high-resolution medical images for diagnostic purposes. The core function of the Signa HDxt is to generate detailed images of the body's internal structures using strong magnetic fields and radio waves.
8
Matlab by MathWorks
Sourced in United States, United Kingdom, Germany, Canada, Japan, Sweden, Austria, Morocco, Switzerland, Australia, Belgium, Italy, Netherlands, China, France, Denmark, Norway, Hungary, Malaysia, Israel, Finland, Spain
MATLAB is a high-performance programming language and numerical computing environment used for scientific and engineering calculations, data analysis, and visualization. It provides a comprehensive set of tools for solving complex mathematical and computational problems.
9
Magnetom trio by Siemens
Sourced in Germany, United States, United Kingdom
The Magnetom Trio is a magnetic resonance imaging (MRI) system manufactured by Siemens. It is designed to produce high-quality images of the body's internal structures. The Magnetom Trio uses a powerful superconducting magnet to generate a strong magnetic field, which, in combination with radio waves, allows for the detailed visualization of the body's anatomy and physiology.
10
Multihance by Bracco
Sourced in Italy, Germany, United States, China
MultiHance is a contrast agent used in magnetic resonance imaging (MRI) procedures. It is a paramagnetic agent that enhances the visualization of internal body structures during the MRI scan. The core function of MultiHance is to improve the contrast between different tissues, allowing for better detection and evaluation of potential abnormalities.

More about "Gadolinium DTPA"

Gadolinium DTPA (Gd-DTPA) is a contrast agent widely used in magnetic resonance imaging (MRI) to enhance the visualization of various tissues and pathologies.
It consists of the gadolinium (Gd) ion chelated with the diethylenetriaminepentaacetic acid (DTPA) ligand.
Gadolinium DTPA is a powerful diagnostic tool, utilized in clinical practice to assess a range of conditions, such as brain lesions, spinal cord abnormalities, and vascular diseases.
Its ability to alter the relaxation times of protons in the body allows for improved contrast and detail in MRI scans, making it a crucial component of many imaging procedures.
Researchers studying Gadolinium DTPA can leverage advanced tools like PubCompare.ai to optimize their research protocols, locate relevant literature, and ensure reproducibility and accuracy in their work.
This AI-powered platform helps researchers compare protocols from various sources, including published literature, preprints, and patents, to identify the most effective and reliable approaches.
Other commercially available Gd-DTPA formulations, such as Magnevist, Omniscan, and MultiHance, are also widely used in clinical practice.
These contrast agents share similar properties and applications, but may have slight variations in their chemical composition or pharmacokinetic profiles.
Advanced MRI scanners, like the Discovery MR750, Magnetom Avanto, Signa HDxt, and Magnetom Trio, often incorporate Gadolinium DTPA-based contrast agents to enhance the quality and diagnostic value of their images.
Researchers can utilize software tools like MATLAB to analyze and process MRI data, including Gadolinium DTPA-enhanced scans, to extract valuable insights and drive their investigations forward.
By leveraging the insights and capabilities of Gadolinium DTPA, researchers can make informed decisions, ensure the reproducibility of their work, and ultimately contribute to advancements in medical imaging and patient care.