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Ginger root

Ginger root, the underground stem of the Zingiber officinale plant, is a versatile and widely studied herb with a rich history in traditional medicine.
This aromatic rhizome is known for its potential health benefits, including anti-inflammatory, antioxidant, and digestive properties.
Ginger root research has explored its applications in areas such as nausea and vomiting, pain management, and metabolic health.
With its diverse bioactive compounds, including gingerols, shogaols, and zingerone, ginger root continues to be a subject of intense scientific investigation.
Leveraging the power of PubCompare.ai, researchers can streamline their ginger root studies, identify optimal protocols, and enhance the reproducibility and accuracy of their findings.
Explore the vast potential of this remarkable botanical with the support of PubCompare.ai's AI-driven platform.

Most cited protocols related to «Ginger root»

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Publication 2010
Angelica Angelica sinensis root extract Apricot Cassia Cinnamomum cassia Cinnamon Coptis Coptis chinensis Coptis chinensis root Cortex, Cerebral Cytoplasmic Granules Ethanol Fruit Ganoderma ginger extract ginger root Ginseng huangbai Japanese Lingzhi Metals, Heavy Panax ginseng Pesticide Residues Phellodendron Plant Roots Powder
Capsules used for the study were provided by the Juice Plus Company/NSA LLC, Collierville, TN, USA and manufactured for Europe by Natural Alternatives International (NAI), Manno, Switzerland. The capsules contained powdered juice concentrate derived from 36 different fruits, vegetables, and berries including juice and pulp from different vegetal matrices, namely Juice PLUS+® Vineyard (a berry blend), Juice PLUS+® Fruit Blend and Juice PLUS+® Vegetable Blend, which were kindly supplied by the Juice PLUS+® company. In detail, the powder samples differed for their composition: Juice PLUS+® Vineyard (hereafter called “berry blend”) contained 750 mg of dried powder blend of juice and pulp from grapes and berries (45.7%) including Concord grape, blueberry, cranberry, blackberry, bilberry, raspberry, redcurrant, blackcurrant, elderberry, in varying proportions, besides green tea, ginger root, grape seed, artichoke leaf powder, cocoa powder, and pomegranate powder. Juice PLUS+® Fruit Blend (“fruit blend”) instead contained 750 mg of dried powder blend of juice and pulp (52%) of apple, orange, pineapple, cranberry, peach, acerola cherry, papaya, in varying proportions, beet root, date, and prune. Lastly, Juice PLUS+® Vegetable Blend (“vegetable blend”) contained 750 mg of dried powder blend of juice and pulp (60%) of carrot, parsley, beet, kale, broccoli, cabbage, tomato, and spinach, in varying proportions, as well as sugar beet, garlic powder, oat, and rice bran. Moreover, the fruit and the vegetable powders were enriched with vitamins C, and folic acid) and with a natural carotenoid and tocopherol blend. The berry blend powder was enriched with vitamins C and folic acid as well as with a natural tocopherol blend.
Publication 2017
Ascorbic Acid Beets Berries Beta vulgaris Bilberries Blackberries Black Currant Blueberries Broccoli Cabbage Capsule Carotenoids Carrots Cherry, Acerola Cocoa Powder Cranberry Cynara scolymus leaf Dental Pulp Elderberry Folic Acid Fruit Fruit Juices Garlic ginger root Grapes Green Tea Kale Oryza sativa Papaya Peach Petroselinum crispum Pineapple Plant Roots Powder Raspberries Spinach Tomatoes Vegetables Vitamin E
The DMBI is a Chinese Chan-based lifestyle intervention based on the Chanwuyi tradition (i.e., Zen, martial arts and healing) and the Chan medical principle. According to the Chan medical principle, majority of mental and physical health problems are due to the blockage of orifices (i.e., bodily openings) and stagnation of Qi and blood circulation, which are likely resulted from unhealthy living style and attitude. Thus, adoption of a healthy lifestyle and positive thinking is a key to unblock the orifices and smooth the Qi and blood circulation, so as to enhance health. Emphasizing integrative treatment of the mind and the body, the principle of DMBI is to enhance mental and physical health by changing daily dietary and exercise habits and to improve the psychological well-being by understanding the root of problems in accordance with Buddhist philosophy (Chan, 2010 , 2013 ).
The intervention was conducted by a clinical psychologist who is familiar with the DMBI model. Throughout the 12 training sessions, the participants were taught the fundamental principles and techniques of DMBI, and their progress was closely monitored by the trainer. There were three intervention components: (1) Advise diet modification by reducing intake of food (e.g., ginger, garlic, green onions, spicy foods, eggs, meat, and fish) that generates excessive internal heat and adversely affects moods and physical health based on Chan medical principle; and consuming food that was good for health everyday (e.g., fresh vegetables, fruits, grains, beans, mushrooms, nuts, and root vegetables). (2) Practice Nei Gong, which is mind–body exercise, composing sets of breathing exercises and gentle and calm movement. For instance, rolling the hands slowly up and down between the chest and the abdomen, resting the hands on the abdomen while quietly observing the breathing. Regular practice of Nei Gong helps reducing stress, and improving overall physical health and the circulation of Qi and the blood. The basic principles and demonstration of Nei Gong have been elaborated on our website (www.chanwuyicenter.com) and in two published books (Chan, 2010 , 2013 ). The practice time was not fixed, and participants were instructed to practice the exercises until they felt warm and relaxed. (3) Improving psychological well-being by increasing awareness and sensitivity to how unrealistic desires (i.e., greed), anger, and obsession (i.e., unrealistic craving for something or somebody) affect mental and physical health, and modifying thought process to alleviate excessive desires, anger, and obsessions.
According to the log record of home practice, 60% participants abstained from or reduced their intake of the “not recommended” food, and 81% participants consumed at least three “recommended” food categories every day. Also, 95% participants practiced Nei Gong every day for an average of about 25 min per day.
Publication 2014
Abdominal Cavity Agaricales Anger Awareness BLOOD Breathing Exercises Cereals Chest Chinese Diet Dietary Modification Eating Eggs Feelings Fishes Food Fruit Garlic Human Body Hypersensitivity Lanugo Meat Mental Processes Mood Movement Nuts Obsessions Onions Physical Examination Plant Roots Psychologist Spices Teaching Vegetables Zingiber officinale
The ginger product used in this study was manufactured by Pure Encapsulations® (Sudbury, MA). Pure Encapsulation’s® ginger (Z. officinale) powder was processed using Good Manufacturing Procedures (GMP). Each capsule contained 250 mg dry extract of ginger root [10:1 (v/v) extraction solvent (ethanol 50 %): root] normalized to 15 mg (5%) of total gingerols. Based on high performance liquid chromatography (HPLC) analysis, a 250 mg capsule of ginger extract (from both batches) contained 5.38 mg (2.15%) 6-gingerol, 1.80 mg (0.72%) 8-gingerol, 4.19 mg (1.78%) 10-gingerol, and 0.92 mg (0.37%) 6-shogaol. Gingerol and shogaol content was verified by an independent laboratory using appropriate HPLC techniques (Integrated Biomolecule Corporation: Tucson, Arizona). The study was conducted using two batches (ZO/06006 and ZO/07006) of ginger powder extract, both of which were tested for gingerols and shogaol content.
The 2.0 g dose used in the study was chosen based on the highest tolerated amount of ginger extract in a phase I dose escalation study in healthy volunteers.28 (link) Also, 2.0 g of ginger extract is equivalent to 20 g of raw ginger root, which would be a large but not unreasonable amount to consume through the diet. Placebo consisted of lactose powder. Ginger powder and lactose were placed into identical opaque red capsules. Placebo and ginger capsules were assembled, stored and dispensed by the Investigational Drug Service of the University of Michigan (U of M IDS). The participants were instructed to take eight 250 mg capsules daily with food and to bring any unused capsules to the final (28 day) study visit.
Publication 2011
8-gingerol 10-gingerol Capsule Diet Ethanol Food ginger extract gingerol ginger root Healthy Volunteers High-Performance Liquid Chromatographies Investigational New Drugs Lactose Placebos Plant Roots Powder shogaol Solvents Zingiber officinale
The ginger product used in this study was manufactured by Pure Encapsulations® (Sudbury, MA). Pure Encapsulation’s® ginger (Z. officinale) powder is processed using Good Manufacturing Procedures (GMP). Each capsule contained 250 mg dry extract of ginger root [10:1 (v/v) extraction solvent (ethanol 50 %):root] standardized to 15 mg (5%) of total gingerols. Based on HPLC analysis a 250 mg capsule of ginger extract contained 5.38 mg (2.15%) 6-gingerol, 1.80 mg (0.72%) 8-gingerol, 4.19 mg (1.78%) 10-gingerol, and 0.92 mg (0.37%) 6-shogaol. Gingerol content was verified by an independent laboratory using appropriate HPLC techniques (Integrated Biomolocule Corporation: Tucson, Arizona). The entire study was conducted using a single batch of ginger powder extract to optimize product consistency. β-17-estradiol acetate, and the enzymes β-glucuronidase (Type IX-A from E.coli) and sulfatase (Type H-1 from Helix pomatia), were purchased from Sigma- Aldrich Inc (St. Louis, MO). Sodium phosphate and sodium acetate (ACS certified) were purchased from Fisher Scientific (Fair Lawn, NJ). Six, 8, and 10-gingerols and 6-shogaol were purchased from Chromadex (Santa Ana, CA, USA) (Fig. 1). Standards were found to be >95% pure per HPLC analysis. Pelargonic acid vanillylamide (PAV), the internal standard, was obtained from Sigma (St. Louis, MO, USA) and is ≥ 97% pure. Acetonitrile, methanol, hexane and de-ionized water were all HPLC grade (Burdick & Jackson, Muskegon, MI, USA). HPLC grade ethyl acetate and ammonium acetate were purchased from Fisher Scientific (Pittsburgh, PA, USA). HPLC grade acetic acid was obtained from J.T. Baker (Phillipsburg, NJ, USA).
Publication 2008
8-gingerol 10-gingerol Acetate Acetic Acid acetonitrile ammonium acetate beta-Glucuronidase Capsule Enzymes Escherichia coli Estradiol Ethanol ethyl acetate ginger extract gingerol Helix (Snails) Hexanes High-Performance Liquid Chromatographies Methanol pelargonic acid vanillylamide Plant Roots Powder shogaol Sodium Acetate sodium phosphate Solvents Sulfatases Zingiber officinale

Most recents protocols related to «Ginger root»

The fresh, ginger (Z. officinale)
roots were collected from Nopha district Ilu Abba Boor Zone, Oromia,
Ethiopia. The collected and dried ginger roots were pulverized to
fine dust by using an electric grinder and preserved in plastic containers.
The extracts of ginger root powder were prepared by mixing 10 g with
100 mL of 70% acetone under vigorous stirring for 15 min, kept for
48 h at room temperature, and filtered through Whatman No.1 filter
paper. The extract was heated at 70 °C for 20 min to remove acetone
and then cooled at room temperature. Then the filtrate was stored
in a refrigerator at 4 °C in order to be used for further experiments.44 (link),45 (link)
Publication 2024
Ginger roots were purchased from a local grocery store and maintained in a refrigerator till use. One hundred grams ginger roots were homogenized, and the juice was collected through 3 layers chess cloth filtering, followed by centrifugation and 0.2 μm filter sterilization. After freeze-drying, ginger root powders were completely dissolved in 750 μL DMSO. Finally, the solution was reconstituted to 75 mL with cell culture media, followed by 0.2 μm filter sterilization. The sterile ginger root juice was used for total phenol content measurement and cell culture treatments. The phenolic content in the ginger juice was measured using the Folin-Ciocalteu assay as previously reported, expressed as gallic acid equivalent.14 (link)
Publication 2024
Not available on PMC !
Ginger (Zīngiber officināle) is a perennial herb 0.5-1 m tall, with a creeping, nodular, cylindrical, pale yellow or reddish root. The leaves are dark green, grow from the root and are 17 cm long, narrow, pointed, bilobed and covered with scales. The leaves are in a row, and the leaf sheaths are arranged one above the other. The flower stem is thinner than the leaf stem, usually about 12 cm tall, covered with outer leaves.
At the top there are spike-shaped inflorescences, and in the axils of the leaves there are flowers. Lateral inflorescences, the edges are light yellow, the top may have a white tip. The calyx is tubular (3 corollas grown together).
The inflorescence consists of three incompletely separated yellow petals, oval in shape, tapering towards the tip, the posterior calyx is wider when viewed from the side, and bent over the pistil. Lips are almost round, about 12 mm in diameter, wide, light purple or red purple, spotted and have a cream or yellow base. The side lobes are not completely separated from the middle lobes. Anthers are single, cream-colored, and the appendage at the tip of the anther is dark purple in color. The mother seed consists of three leaves that grow together. This type of plant does not yield when grown under normal conditions. The horn is propagated by root development [2] .
The great famous medicine scientist Hakim Abu Ali ibn Sina wrote in his work "The Laws of Medicine" that it is necessary to add ginger to the ointments used in the treatment of many diseases. Ginger is recommended for consumption by sick and healthy people. In medicine, ginger root is recommended to be used as the main active agent in more than 25 different diseases in complex therapy. Ginger is scientifically called singibera, which means "horned root" and is widely used as a "universal medicine". Ginger contains complex minerals, vitamins, all types of amino acids necessary for human life: calcium, sodium, phosphorus, zinc, iron, magnesium, vitamins A, B1, B 2 , C, nicotinic acid and essential oils. Treatment with ginger is indicated in most diseases. In particular, it is recognized as an antiviral agent for colds. In the treatment of colds, ginger has antiviral, mucolytic, antiinflammatory, antibacterial, antihistaminic, expectorant properties [3;4] .
The chemical composition of the root of ginger, the main components that provide its pharmacological activity are essential oil and phenolic compounds, that is, gingerol and shogaol. Essential oils are 1-4%. More than 100 components have been identified in ginger, of which sesquiterpenes (50% of the total amount) -α-and β-zingiberenes, curcumens, βsesquiphelandrene, β-bisabolene, α-and β-farnesenes, zingiberol and others are the main ones. The main root contains a small amount of monoterpenes -geraniol (9%), linalool (1%), borneol, geranial, geraniacetate, isoborneols, which give a characteristic smell.
Essential oil also contains aldehydes, alcohols, ketones and alkanes. The region where it is grown has a significant effect on the composition and amount of essential oil in ginger.
Gingerols are the non-volatile phenolic compounds in ginger root that give it its bitter taste. The main of them is gingerol-6, gingerol-8 and gingerol-10 in smaller amounts. During drying and storage, gingerols are partially dehydrated to shogaols, respectively, which can then be transformed into paradol, gingerdiones, gingerdiols, and gingerdiol acetates.
Also, ginger root contains amino acids, proteins, lipids (6-8%), proteolytic enzymes, vitamins, tannins, sterols, starch (up to 50%), monosaccharides, inorganic substances. Vitamins are represented by ascorbic acid, niacin, thiamin, riboflavin and a small amount of retinoid and tocopherols.
The characteristics of spices belonging to the ginger family, their biological value have been studied. A commodity price is given for bread and flour confectionery products made with the addition of turmeric and ginger.
Thus, the authors concluded that the introduction of plant supplements containing iodine into newly developed recipes of bread and flour confectionery products does not impair their consumption characteristics and, at the same time, remains an additional source of iodine in food products.
For the first time, the composition of capsules containing the dry extract of medicinal ginger, which dissolves quickly, was developed by the author, theoretically and research-based. In this study, a medicinal preparation in the form of capsules was obtained based on dry extracts of medicinal ginger. Antioxidant, antitoxic, analgesic and hepatoprotective effects of ginger have been studied. The amount of essential oils, including gingerol and shogaol, in the extract and finished product was determined by the high-performance liquid chromatography method [5;6] .
Experimental studies show that the consumption of ginger root improves salivation.
The article discusses the results of a spectrophotometric study of accumulation of flavonoids in the weakly polar fraction of ginger root fruit (Zingiber officinale Roscoe) in the system of immiscible solvents (aqueous solution of ethanol -rapeseed oil) through two-phase extraction. The role of a polar extractor has been shown to optimize the process of extracting biologically active substances from primary raw materials.
Publication 2024
A total of 432 day-old male broiler chicks (Ross 708 strain) were completely randomized to six dietary treatment groups. Each treatment contained six replicate pens, each with twelve chicks allocated to each pen. The trial lasted for 42 days (6 weeks). Treatment 1 (CON) consisted of chicks fed unmedicated corn–soybean meal (SBM). Treatment 2 (MX) consisted of chicks given unmedicated corn–SBM basal with bacitracin methylene disalicylate (BMD) added at 0.055 g/kg diet. Treatment 3 (GRE-1), treatment 4 (GRE-2), treatment 5 (GRE-3), and treatment 6 (GRE-4) consisted of chicks given unmedicated corn–SBM basal with dietary ginger root extract added at 0.375%, 0.75%, 1.5%, and 3% levels of the diet, respectively. Ginger root extract was purchased commercially from Sabinsa Corporation, East Windsor, NJ. The chicks spent their first 21 days in a battery cage and were later moved to a floor enclosure with a nipple drinker line, a hanging feeder, and clean, new litter. Diets (Table 1 and Table 2) used in experiments were designed so as to adhere to, meet, or slightly exceed nutrient requirements recommended in the Aviagen 2022 Ross broiler nutrition specification handbook. Starter diets were supplied as crumble from day 1 to day 21, and grower diets were fed as pellets from day 22 to day 42 of the experiment. During the 42-day trial, the birds had free access to food and water.
Publication 2024
Ginger root capsule extract (GRCE) (Solaray, Park City, UT, USA) was purchased from a local pharmacy, as a food supplement sold in 250 mg capsules. As stated in the pamphlet, the capsules contain ginger (Zingiber officinale) (root extract) (guaranteed 12.5 mg (5%) gingerols). We had already reported the GRCE phytochemical analysis and toxicity evaluation in our previous paper [21 (link)]. The phytochemical analysis revealed that 10-gingerol (525.418 μg/mL), 6-gingerol (443.182 μg/mL), 8-gingerol (360.897 μg/mL), 6-shogaol (369.816 μg/mL), and 1-Dehydro-6-gingerdione (304.115 μg/mL) were the main compounds of GRCE [21 (link)]. Injectable diclofenac sodium and saline solution (0.9%) were also purchased from a local pharmacy in Cluj-Napoca.
Publication 2024

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More about "Ginger root"

Ginger (Zingiber officinale) is a versatile and widely studied rhizome (underground stem) with a rich history in traditional medicine.
This aromatic botanical is known for its potential health benefits, including anti-inflammatory, antioxidant, and digestive properties.
Ginger research has explored its applications in areas such as nausea, vomiting, pain management, and metabolic health.
Ginger contains a diverse array of bioactive compounds, including gingerols, shogaols, and zingerone, which continue to be the subject of intense scientific investigation.
To streamline ginger research and enhance reproducibility, researchers can leverage the power of AI-driven platforms like PubCompare.ai.
This tool can help identify optimal protocols from literature, preprints, and patents, while providing AI-driven comparisons to guide the selection of the most effective approaches.
Ginger's potential health benefits extend beyond its anti-inflammatory and digestive properties.
Studies have also explored its impact on cholesterol levels, with compounds like cholesterol/cholesterol ester-glo playing a role in these investigations.
Additionally, ginger research has utilized techniques like intracellular lipid staining assays (Steatosis Colorimetric Assay Kit) and TRIzol reagent to analyze its effects on lipid metabolism and gene expression.
To ensure the accuracy and reliability of ginger research, researchers may employ high-quality filtration materials, such as Whatman No. 1 filter paper and the Milli-Q Integral Water Purification System, to maintain the integrity of their samples and reagents.
The use of specialized equipment, like a hybridization oven, can also play a crucial role in the experimental protocols.
By leveraging the insights gained from ginger's rich history, diverse bioactive compounds, and cutting-edge research tools, scientists can continue to unravel the full potential of this remarkable botanical and advance our understanding of its therapeutic applications.
With the support of AI-driven platforms like PubCompare.ai, ginger research can reach new heights, driving innovation and improving human health.