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Lidocaine

Lidocaine is a widely used local anesthetic and antiarrhythmic drug.
It works by blocking sodium channels, preventing the propagation of action potentials and reducing the excitability of nerves.
Lidocaine is commonly administered topically, intravenously, or as an injectable to provide pain relief and control cardiac arrhythmias.
Researching the optimal use of Lidocaine is crucial for various medical applications, from pain management to cardiac care.
PubCompare.ai is an AI-powered platform that can help streamline your Lidocaiine research by easily locating relevant protocols from literature, pre-prints, and patents, and providing AI-driven comparisons to identify the best protocols and products for your needs.
Take the guesswork out of your Lidocaine research with the help of PubCompare.ai's powerful tools.

Most cited protocols related to «Lidocaine»

1
Whole-cell Patch-clamp Electrophysiology
Cited 160 times
Data were obtained using conventional whole cell patch-clamp techniques.
Micropipette fabrication and data acquisition were as described previously for
undiseased donor heart[85] (link). Axopatch 200 amplifiers, Digidata 1200 converters,
and pClamp software were used (Axon Instruments/Molecular Devices). Experiments
were performed at 37°C.
The standard bath solution contained, in mM: NaCl 144,
NaH2PO4 0.33, KCl 4.0, CaCl2 1.8,
MgCl2 0.53, Glucose 5.5, and HEPES 5.0 at pH of 7.4, and pipette
solutions contained K-aspartate 100, KCl 25, K2ATP 5,
MgCl2 1, EGTA 10 and HEPES 5. The pH was adjusted to 7.2 by KOH
(+15−20 mM K+).
For L-type Ca2+ current measurement, the bath solution contained
in mM: tetraethylammonium chloride (TEA-Cl) 157, MgCl2 0.5, HEPES 10,
and 1 mM CaCl2, or BaCl2, or SrCl2 (pH 7.4 with
CsOH). The pipette solution contained (in mM) CsCl 125, TEA-Cl 20, MgATP 5,
creatine phosphate 3.6, EGTA 10, and HEPES 10 (pH 7.2 with CsOH).
For Na+/Ca2+ exchange current measurement, the
bath solution contained, (in mM): NaCl 135, CsCl 10, CaCl2 1, MgCl21, BaCl2 0.2, NaH2PO4 0.33, TEACl 10, HEPES 10,
glucose 10 and (in µM) ouabain 20, nisoldipine 1, lidocaine 50, pH 7.4.
The pipette solution contained (in mM): CsOH 140, aspartic acid 75, TEACl 20,
MgATP 5, HEPES 10, NaCl 20, EGTA 20, CaCl2 10 (pH 7.2 with CsOH).
O'Hara T., Virág L., Varró A, & Rudy Y. (2011). Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation. PLoS Computational Biology, 7(5), e1002061.
Publication 2011
Adenosine Triphosphate, Magnesium Salt Aspartate Aspartic Acid Axon barium chloride Bath Cells cesium chloride Egtazic Acid Glucose Heart HEPES Lidocaine Magnesium Chloride Medical Devices Nisoldipine Ouabain Phosphocreatine Sodium Chloride Tetraethylammonium Chloride Tissue Donors
2
Surgical Preparation for In Vivo Voltammetry
Cited 21 times
All animal procedures presented in this paper followed the University of Washington Institutional Animal Care and Use Committee guidelines. Surgical preparation for in vivo voltammetry used aseptic technique. Male rats weighing between 300g and 350g (Charles River, CA) were anesthetized with isoflurane and placed in a stereotaxic frame. The scalp was swabbed with 10% povidone iodine, bathed with a mixture of lidocaine (0.5 mg/kg) and bupivicaine (0.5 mg/kg), and incised to expose the cranium. Holes were drilled and cleared of dura mater above the nucleus accumbens core (1.3-mm lateral and 1.3-mm rostral from bregma), the dorsolateral striatum (4.3-mm lateral and 1.2-mm rostral from bregma), and/or the nucleus accumbens shell (0.8-mm lateral and 1.2-mm rostral from bregma) for microsensors, above the midbrain (1.0-mm lateral and 5.2-mm caudal from bregma) for a stimulating electrode in some animals, and at convenient locations for a reference electrode and three anchor screws. The reference electrode and anchor screws were positioned and secured with cranioplastic cement, leaving the stimulating electrode and working electrode holes exposed. The microsensors were then attached to the voltammetric amplifier and lowered into the target recording regions (7.0-mm ventral of dura mater for nucleus accumbens, 4.0-mm ventral of dura mater for dorsolateral striatum). For animals in which a stimulating electrode was implanted, the voltammetric waveform was applied at 10 Hz and dopamine monitored. Next, the stimulating electrode (Plastics One, VA) was lowered 7.0 mm below dura mater and electrical stimulation (60 biphasic pulses, 60 Hz, ±120 µA, 2 ms/phase) was applied via an optically isolated, constant-current stimulator (A-M Systems, WA). If an evoked change in dopamine concentration was not observed at the working electrode, the stimulating electrode was positioned 0.2 mm more ventral. This was repeated until dopamine efflux was detected following stimulation. It was then lowered further in 0.1-mm increments until dopamine release was maximal. This is usually when the stimulating electrode is 8.4-mm ventral from dura mater. Finally, cranioplastic cement was applied to the part of the cranium that is still exposed to secure the stimulating electrode and microsensor(s).
Clark J.J., Sandberg S.G., Wanat M.J., Gan J.O., Horne E.A., Hart A.S., Akers C.A., Parker J.G., Willuhn I., Martinez V., Evans S.B., Stella N, & Phillips P.E. (2009). Chronic microsensors for longitudinal, subsecond dopamine detection in behaving animals. Nature methods, 7(2), 126-129.
Publication 2009
Animals Asepsis Bupivacaine Cranium Dental Cements Dopamine Dura Mater Institutional Animal Care and Use Committees Isoflurane Lidocaine Males Mesencephalon Neostriatum Nucleus Accumbens Operative Surgical Procedures Povidone Iodine Pulses Rattus Reading Frames Rivers Scalp Stimulations, Electric
3
Automated Chemical-Disease Relation Annotation
Cited 15 times
We performed manual annotation of all chemicals and diseases mentioned in the 1500 articles. For each entity occurrence, we not only annotated its text span but also assigned a relevant concept identifier from MeSH (22 ). As shown in Figure 1, three diseases mentioned in the abstract were highlighted by our automated tool for potential consideration by the MeSH annotators, along with three occurrences of the same chemical (Lidocaine).

Annotation example shown in our annotation tool, PubTator.

As indicated above, we largely leveraged the previous annotation of chemical-disease relationships from the CTD-Pfizer dataset for 1400 of the 1500 articles with few changes: (i) we removed relations that required entities not found in abstracts; (ii) we removed relations that were not disease specific (e.g. ‘Drug-Related Side Effects and Adverse Reactions’ (D064420)); and (iii) we updated a few CTD relations due to the MeSH vocabulary changes (the CTD-Pfizer project was conducted in years 2011/12, and the MeSH vocabulary has changed since then).
We performed new manual annotation of chemical–disease relations for the remaining 100 articles in the test set. For the BioCreative V challenge task, the CID relations refer to two types of relationships between a chemical and a disease in CTD:

Putative mechanistic relation between a chemical and a disease indicates that the chemical may play a role in the etiology of the disease (e.g. exposure to chemical X causes lung cancer). Figure 1 shows an example of such a CTD curated relationship between Lidocaine and Heart Arrest (disease term for the synonym ‘asystole’ used by the authors in the abstract).

Biomarker relation between a chemical and a disease indicates that the chemical correlates with the disease (e.g. increased abundance in the brain of chemical X correlates with Alzheimer disease).

CTD curators used their standard curation process for CDR curation (23 (link)). Curation was limited to the title and abstract except in cases where reference to the full text was required for clarification; abstracts that required full-text curation were removed from the corpus. In addition to CDR curation, all observed interactions and relationships applicable to CTD were curated for each abstract. CTD triaged and/or curated 143 articles in conjunction with BioCreative V; the final 100 selected for inclusion in the Test Dataset represented abstract-only curation for CDRs.
Li J., Sun Y., Johnson R.J., Sciaky D., Wei C.H., Leaman R., Davis A.P., Mattingly C.J., Wiegers T.C, & Lu Z. (2016). BioCreative V CDR task corpus: a resource for chemical disease relation extraction. Database: The Journal of Biological Databases and Curation, 2016, baw068.
Publication 2016
Alzheimer's Disease Biological Markers Brain Cardiac Arrest Drug Reaction, Adverse Lidocaine Lung Cancer
4
Calcium Imaging and DREADD Surgeries in Mice
Cited 14 times
Mice were anesthetized with 1.5 to 2.0% isoflurane for surgical procedures and placed into a stereotactic frame (David Kopf Instruments, Tujunga, CA). Lidocaine (2%; Akorn, Lake Forest, IL) was applied to the sterilized incision site as an analgesic, while subcutaneous saline injections were administered throughout each surgical procedure to prevent dehydration. In addition, carprofen (5mg/kg) and dexamethasone (0.2mg/kg) were administered both during surgery and for 7 days post-surgery with amoxicillin.
For calcium imaging experiments, mice underwent two separate surgical procedures. First, mice were unilaterally microinjected with 500 nanoliters of AAV1.Syn.GCaMP6f.WPRE.SV40 virus at 50nl/min into the dorsal CA1 using the stereotactic coordinates: −2.1 mm posterior to bregma, 2.0 mm lateral to midline and −1.65 mm ventral to skull surface. Two weeks later, the microendoscope (a gradient refractive index lens) was implanted above the previous injection site. For the procedure, a 2.0mm diameter circular craniotomy was centered 0.5mm medial to the virus injection site. Artificial cerebrospinal fluid (ACSF) was repeatedly applied to the exposed tissue to prevent drying. The cortex directly below the craniotomy was aspirated with a 27-gauge blunt syringe needle attached to a vacuum pump. The microendoscope (0.25 pitch, 0.50 NA, 2.0mm in diameter and 4.79 in length, Grintech Gmbh) was slowly lowered with a stereotaxic arm above CA1 to a depth of 1.35mm ventral to the surface of the skull at the most posterior point of the craniotomy. Next, a skull screw was used to anchor the microendoscope to the skull. Both the microendoscope and skull screw were fixed with cyanoacrylate and dental cement. Kwik-Sil (World Precision Instruments) covered the microendoscope. Two weeks later, a small plastic baseplate was cemented onto the animal’s head atop the previously formed dental cement. Debris was removed from the exposed lens with ddH2O, lens paper and forceps. The microscope was placed on top of the baseplate and locked in a position in which the field of focus was in view, so that cells and visible landmarks, such as blood vessels, appeared sharp and in focus. Finally, a plastic cover was fit into the baseplate and secured by magnets.
For aged DREADD experiments, mice were bilaterally microinjected with 700 nanoliters of Lentivirus CaMK2.hM3Dq.T2A.EGFP/dTomato virus at 100nl/min into the dorsal CA1 using the stereotactic coordinates: −1.80 mm posterior to bregma, +/−1.50 mm lateral to midline, −1.60 mm ventral to skull surface; −2.50 mm posterior to bregma, +/−2.00 mm lateral to midline, −1.70 mm ventral to skull surface.
Cai D.J., Aharoni D., Shuman T., Shobe J., Biane J., Song W., Wei B., Veshkini M., La-Vu M., Lou J., Flores S., Kim I., Sano Y., Zhou M., Baumgaertel K., Lavi A., Kamata M., Tuszynski M., Mayford M., Golshani P, & Silva A.J. (2016). A shared neural ensemble links distinct contextual memories encoded close in time. Nature, 534(7605), 115-118.
Publication 2016
Amoxicillin Analgesics Animals Blood Vessel Calcium, Dietary carprofen Cells Cerebrospinal Fluid Cortex, Cerebral Craniotomy Cranium Cyanoacrylates Dehydration Dental Cements Dexamethasone Forceps Forests Head Isoflurane Lens, Crystalline Lentivirinae Lidocaine Microscopy Mus Needles Operative Surgical Procedures Reading Frames Saline Solution Simian virus 40 Subcutaneous Injections Syringes Tissues Vacuum Virus
5
Unilateral Viral Transduction in Mice
Cited 14 times
For experiments investigating general transduction efficiency three to seven mice were used per serotype and brain region (Figure 1). Animals were deeply anesthetized with a mixture of ketamine and medetomidine (KM; 2.5 mg ketamine-HCl and 0.02 mg medetomidine-HCl/25 g mouse weight) injected intraperitoneally, and positioned in a stereotaxic frame (Kopf Instruments, Tujunga, CA; Stereotaxic System Kopf 1900). A local anaesthetic (lidocaine) was applied subcutaneously before exposure of the skull. Small holes were drilled into the skull and injections were performed unilaterally using a thin glass pipette with 80 nl of virus solution (titer: 9.6 * 1011 viral genomes (VG)/ml in PBS) at a flow rate of 20 nl/min (World Precision Instruments, Sarasota, FL; Nanoliter 2000 Injector). Glass pipettes (World Precision Instruments, Sarasota, FL; Glass Capillaries for Nanoliter 2000; Order# 4878) had been pulled with a long taper and the tip was cut to a diameter of 20-40µm. After the injection, the pipette was left in place for 3 minutes, before being slowly withdrawn. Coordinates for injections were (in mm: caudal, lateral, and ventral to bregma): striatum (0.9, 1.5, 3.2), hippocampus (-1.9, 1.6, 1.6), cortex (-2.9, 4.25, 2.5). After surgery, anesthesia was neutralized with 0.02 ml atipamezole. Mice were monitored daily and intraperitoneal injections of carprofen (0.2 ml of 0.5 mg/ml stock) were applied on the first days after surgery.
For injections of LPS (Escherichia coli 0127:B8, Sigma-Aldrich, Germany; Figure 4A), mice were anesthetized with 1-2 vol% isoflurane in oxygen and two µl of LPS dissolved in saline (5 µg/µl) were infused at a flow rate of 0.2 µl/min into the striatum (coordinates (in mm) relative to bregma: 0.5, 2.0, -3.5). The cannula was left in place for further 5 minutes before being removed.
In the experiments investigating retrograde transport (Figures 5, 6), three mice were unilaterally injected with 250 nl of a 4:1 mixture of rAAV5 solution (titer s.a.) and cholera toxin subunit B-alexa fluor 555 conjugate (Invitrogen, C-22843; 1 mg/ml in PBS) into the hippocampus (same coordinates as above). Surgery, pharmacology, and injection were carried out as above.
When analyzing the time-course of expression (Figure 7 and Figure S4), mice received 80 nl injections into the striatum (titer: 1.01 * 1012 VG/ml; same coordinates as above). One hemisphere was injected with either a (self-complementing) scGFP/scCherry and the other hemisphere was injected with either a (single strand) ssCherry/ssGFP virus solution. Surgery, pharmacology, and injection as above.
Aschauer D.F., Kreuz S, & Rumpel S. (2013). Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain. PLoS ONE, 8(9), e76310.
Publication 2013
Alexa Fluor 555 Anesthesia Animals atipamezole Brain Cannula Capillaries carprofen Cholera Cortex, Cerebral Cranium Escherichia coli Injections, Intraperitoneal Isoflurane Ketamine Ketamine Hydrochloride Lidocaine Local Anesthesia Medetomidine Mice, House Operative Surgical Procedures Oxygen Protein Subunits Reading Frames Saline Solution Seahorses Striatum, Corpus Toxins, Chimeric Viral Genome Virus

Most recents protocols related to «Lidocaine»

1
Lidocaine Preservative-Free Intranasal Formulation
Not available on PMC !

Example 6

A lidocaine preservative free intranasal formulation with combination of other drugs is prepared using the ingredients set forth in Table 4 for Examples 6-8.

TABLE 4
Example 6Example 7Example 8
Compositionmg/spraymg/spraymg/spray
Lidocaine101010
Epinephrine——0.01
Meloxicam15——
Ketamine—15
Citric acid monohydrate   3.503.253.0
Purified WaterQsQsQs

The formulation is prepared as follows: Add citric acid monohydrate to purified water while stirring and mix till a clear solution is observed. Add lidocaine base or salt, combination drug and other optional excipients while stirring and mix for 30 minutes till a clear solution is formed. Filter the clear solution using sterile 0.2 micron pore size filter and fill the solution in a glass bottle aseptically and tightly crimp metered dose mechanical pump.

US11857520B2. Therapeutic composition of intranasal lidocaine (2024-01-02). Nortic Holdings Inc. [US]. Inventors: S. George Kottayil [US], Amresh Kumar [US], Prasanna Sunthankar [US], Vimal Kavuru [US], Kamalkishore Pati [US].
Patent 2024
Citric Acid Monohydrate Drug Combinations Epinephrine Excipients Ketamine Lidocaine Meloxicam Pharmaceutical Preservatives Sodium Chloride Sterility, Reproductive
2
Surgical Techniques for Eyelid Skin Cancer Removal
Anesthesiologists used neuroleptic sedation for each patient with a combination of ketamine, midazolam, fentanyl and propofol. The surgeon used loupes with a 3.3X magnification and a headlight. The tumour was assessed, measured (Figure 1A), and marked with standard four millimetre surgical margins for BCC and seven millimeter surgical margins for melanoma in situ (MIS). The width of the excised area was documented. The donor tissue width was estimated and marked (Figure 1B). The donor lid was then stretched horizontally, ensuring that the secondary defect could undergo direct closure. One drop of topical anesthesia was placed in each eye and the operative site was prepared with controlled use of chlorhexidine to limit the risk of corneal toxicity. The surgeon performed subcutaneous infiltration of the tumor and donor sites using lidocaine 2% with epinephrine 1:100,000; 2 ml or less per eyelid. All tissue was handled with 0.5 mm toothed forceps to preserve its architecture and integrity.
McDonald H.M., McDonald K.A, & McDonald H. (2023). The free bilamellar autograft (FBA) procedure: A comprehensive case series of an alternative surgical approach to reconstruction of large eyelid defects. Frontiers in Surgery, 10, 1038952.
Publication 2023
Anesthesiologist Antipsychotic Agents Chlorhexidine Cornea Epinephrine Eyelids Fentanyl Forceps Ketamine Lidocaine Melanoma Midazolam Neoplasms Patients Propofol Sedatives Surgeons Surgical Margins Tissue Donors Tissues Topical Anesthetics
3
Minimally Invasive Surgical Techniques for Lumbar Decompression
Cited 1 time
For the PTED group, the surgical procedure (based on the L4–L5 segment of DLS) was performed following methods reported in the literature [18 (link)]. The following steps were performed: (1) part of the superior articular process (SAP) of L5 was removed. A soft pillow was placed under the patients' waist, while the patient was in the lateral decubitus position with their knee and hip flexed. The incision was located 8–12 cm from the midline horizontally and 1–3 cm above the iliac on the side with leg pain. The mixed local anesthetic, which consisted of 30 mL 1:200,000 epinephrine and 20 mL 2% lidocaine, was only used in PTED group. After 5 mL of the mixed anesthetic was inserted into the skin at the entry point, 20 mL was inserted into the trajectory, 15 mL was inserted into the articular process, and 10 mL was inserted into the foramen. Then, 0.8–1.0 cm of skin and the subcutaneous fascia were incised. Drills were used to resect the ventral osteophytes on the SAP. The PTED system (Hoogland Spine Products, Germany) was inserted (Fig. 1). (2) Parts of the ipsilateral ligamentum flavum, perineural scar, and extruded lumbar disc material were completely resected with endoscopic forceps (Fig. 2). (3) The superior endplate of the L5 vertebral body was removed by endoscopic micro punches and a bone knife. Therefore, 270-degree decompression of the traversing nerve root was achieved (Fig. 3). The drainage tube was placed after hemostasis was reached.

Fluoroscopic views. A, B The drill was inserted to resect the LF and the ventral osteophytes on the SAP. C, D The working cannula was placed

Endoscopic views. A Endoscopic view of the hypertrophic posterior longitudinal ligament, extruded disc material, and perineural scar. B–G After the endoscopic instruments were used to carefully remove the vertebral body, ventral decompression of the traversing nerve root (L5) was completed. H The dura mater was torn

Illustrations of the 270-degree PTED. A, B Specific pathologic features of LRS-DLS. C, D Final view of the nerve 270-degree decompression status and the restoration of the lateral recess

For the MIS-TLIF group, the surgical procedure was performed in accordance with methods reported in the literature [19 (link)]. After successful general anesthesia with tracheal intubation, the patient was placed in a prone position with chest and hip pads, and the L4–L5 intervertebral space was marked with X-ray fluoroscopy. The skin and subcutaneous fascia were cut; a trans-muscular surgical corridor was created with two micro-laminectomy retractors docking on the facet joint complex. After exposing the bony structure, part of the lamina and inferior articular process of L4 and the upper L5 articular process were removed with the rongeur on the ipsilateral side, and the hypertrophic ligamentum flavum was peeled backward. If MRI showed contralateral lateral recess stenosis, then predecompression was performed on the contralateral side. After decompression on the dorsal side, the nucleus pulposus and endplate cartilage were removed with forceps. An appropriate cage (Medtronic) filled with autograft from laminectomy was placed in the center of the intervertebral space via the Kambin’s triangle area. After adequate hemostasis was achieved, two drainage tubes were placed and removed when the drainage volume was < 50 mL/d.
Postoperatively, patients was treated with oral nonsteroidal anti-inflammatory drugs and antibiotics for 3 days. All patients were encouraged to perform straight leg raising 1 day postoperatively, and moderate off-bed activity with a brace 2–3 days postoperatively. On the third postoperative day, patients were allowed to go home if their lower extremity pain symptoms were effectively relieved with no evidence of infection. The patient demographics and perioperative outcomes were compared. The VAS score, ODI, and modified Macnab criteria were used to evaluate the clinical outcomes [20 (link)].
Li Y., Cheng X, & Chen B. (2023). Comparison of 270-degree percutaneous transforaminal endoscopic decompression under local anesthesia and minimally invasive transforaminal lumbar interbody fusion in the treatment of geriatric lateral recess stenosis associated with degenerative lumbar spondylolisthesis. Journal of Orthopaedic Surgery and Research, 18, 183.
Publication 2023
Anesthetics Anti-Inflammatory Agents, Non-Steroidal Antibiotics Bones Braces Cannula Cartilage Chest Cicatrix Decompression Drainage Drill Dura Mater Endoscopy Epinephrine Facet Joint Fascia Fluoroscopy Forceps General Anesthesia Hemostasis Hypertrophy Ilium Infection Intubation, Intratracheal Joints Knee Laminectomy Lidocaine Ligaments, Flaval Local Anesthetics Lower Extremity Lumbar Region Muscle Tissue Nervousness Nucleus Pulposus Operative Surgical Procedures Osteophyte Pain Patients Posterior Longitudinal Ligaments Skin Stenosis Tooth Root Transplantation, Autologous Ventral Roots Vertebral Body Vertebral Column X-Rays, Diagnostic
4
Minimally Invasive Breast Mass Excision
All minimally invasive surgical procedures were conducted using a vacuum-assisted Mammotome biopsy system (Devicor Medical Products, Inc.) with the following components: 8G Mammotome rotary cutter, control handle, vacuum suction pump and associated software (Mammotome EX SCMSW5). While undergoing routine sterilization, the patient was placed in a supine or semi-lateral position with their ipsilateral arm lifted up and then draped with a surgical towel. A moderate anesthetic (local anesthesia, 1% lidocaine ≤200 mg.) was administered subcutaneously and underneath the posterior breast space in the surgical area. A ~3-mm incision was made in the predetermined location, which allowed for the proper insertion of the 8G Mammotome needle. The needle was placed underneath the deep surface of the breast mass by US guidance at an appropriate angle so that the breast mass was just inside the groove of the needle (Fig. 1). Repeated rotary cutting was performed to remove the aspirated lesion tissue until no residual lesions were detected in the US images. After completion of the resection, hemostasis was performed in the surgical area to stop bleeding. Compression bandages were applied to all patients for 72 h following the procedure.
US BI-RADS classification. Breast mass classification was based on the latest edition of the US BI-RADS recommendations of the ACR (8 ). Two physicians with >10 years of breast US experience determined the US BI-RADS classification. If the analysis results were inconsistent, the two physicians discussed the results together until a consensus was reached. According to the US BI-RADS management recommendations, category 3 lesions should have a short (6-month) follow-up interval or continued surveillance, while category 4 lesions require biopsy for tissue diagnosis. As there is a marked difference in the treatment of category 3 and 4 lesions by clinicians, category 3 lesions were defined as benign and lesions of category 4 and above were defined as malignant in the present study.
Wang H., Wang Q., Zhang Y, & Peng Y. (2023). Value of ultrasound BI‑RADS classification in preoperative evaluation of the ultrasound‑guided Mammotome‑assisted minimally invasive resection of breast masses: A retrospective analysis. Experimental and Therapeutic Medicine, 25(4), 143.
Publication 2023
Anesthetics Biopsy Breast Compression Bandages Diagnosis Hemostasis Lidocaine Local Anesthesia Minimally Invasive Surgical Procedures Needles Operative Surgical Procedures Patients Physicians RRAD protein, human Sterilization Suction Drainage Tissues Vacuum
5
Latent Myofascial Trigger Point Injection Protocol
The drugs used for latent MTrPs injection containing vitamin B12 (JinYao Corp, Tianjin City, China; 2 ml:1 mg), 2% lidocaine injection (ZhaoHui Corp, Shanghai City, China; 5 ml:100 mg), and compound betamethasone injection (MSD Merck Sharp & Dohme AG, Switzerland; 1 ml: 5 mg betamethasone dipropionate and 2 mg betamethasone sodium phosphate) were diluted to 20 ml with 0.9% saline for a single injection. Injection of latent MTrPs was performed using needle 25 (0.5 mm × 36 mm) and a 20 ml syringe (We Go Corp, Weihai City, China).
The latent MTrPs were mainly found in the sternoclavicular joint, sternocleidomastoid, medial or lateral pterygoid muscles, and splenius capitis muscles by palpation (Figure 1). However, it was difficult to palpate when some trigger points were hidden in muscles, and the final therapeutic effects depend on the accuracy of palpated points (16 (link)). Accurate signs of latent MTrPs can be confirmed by the patient showing “jumping signs,” which may include head retraction, fascial (or forehead) wrinkles, verbal responses, or local twitch responses (LTRs) (11 (link), 12 (link)). Palpation and injection of latent MTrPs were performed according to Travell and Simons’ “Trigger Point Manual” (17 ).
Liu Q., Zhang W., Tian T., Liu Y., Bai H., Hu Q, & Qi F. (2023). Latent myofascial trigger points injection therapy for adult cough variant asthma: A randomized controlled trial. Frontiers in Medicine, 10, 937377.
Publication 2023
Betamethasone betamethasone dipropionate betamethasone sodium phosphate Cobalamins Fascia Feelings Forehead Head Lidocaine MM 36 Muscle Tissue Needles Normal Saline Palpation Patients Pharmaceutical Preparations Pterygoid Muscles Splenius Sternoclavicular Joint Syringes Therapeutic Effect Trigger Point

Top products related to «Lidocaine»

1
Lidocaine by Merck Group
Sourced in United States, United Kingdom, Germany, Canada, China
Lidocaine is a local anesthetic and antiarrhythmic drug used in the medical field. It is a synthetic compound that works by blocking sodium channels in the body, effectively numbing or anesthetizing the affected area. Lidocaine is commonly used to reduce pain and discomfort during various medical procedures.
2
Lidocaine by AstraZeneca
Sourced in Japan, Sweden, United Kingdom, United States, Germany
Lidocaine is a local anesthetic medication used to numb a specific area of the body. It works by blocking the signals that tell the brain about pain in that area.
3
Rompun by Bayer
Sourced in Germany, France, United States, United Kingdom, Canada, Italy, Brazil, Belgium, Cameroon, Switzerland, Spain, Australia, Ireland, Sweden, Portugal, Netherlands, Austria, Denmark, New Zealand
Rompun is a veterinary drug used as a sedative and analgesic for animals. It contains the active ingredient xylazine hydrochloride. Rompun is designed to induce a state of sedation and pain relief in animals during medical procedures or transportation.
4
Scaa 104 by ANPEL
Sourced in China
The SCAA-104 is a laboratory instrument used for the analysis and quantification of various chemical compounds. It is designed to perform specific analytical tasks, but its detailed functionality and intended use are not provided in this response.
5
Xylocaine by AstraZeneca
Sourced in United Kingdom, Sweden, Japan, Germany, Belgium, United States, Australia
Xylocaine is a local anesthetic solution that is used to induce numbness or loss of sensation in a specific area of the body. It contains the active ingredient lidocaine, which works by blocking the transmission of pain signals from the treated area to the brain.
6
Fetal bovine serum (fbs) by Thermo Fisher Scientific
Sourced in United States, China, United Kingdom, Germany, Australia, Japan, Canada, Italy, France, Switzerland, New Zealand, Brazil, Belgium, India, Spain, Israel, Austria, Poland, Ireland, Sweden, Macao, Netherlands, Denmark, Cameroon, Singapore, Portugal, Argentina, Holy See (Vatican City State), Morocco, Uruguay, Mexico, Thailand, Sao Tome and Principe, Hungary, Panama, Hong Kong, Norway, United Arab Emirates, Czechia, Russian Federation, Chile, Moldova, Republic of, Gabon, Palestine, State of, Saudi Arabia, Senegal
Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
7
Dulbecco modified eagle medium (dmem) by Thermo Fisher Scientific
Sourced in United States, China, United Kingdom, Germany, France, Australia, Canada, Japan, Italy, Switzerland, Belgium, Austria, Spain, Israel, New Zealand, Ireland, Denmark, India, Poland, Sweden, Argentina, Netherlands, Brazil, Macao, Singapore, Sao Tome and Principe, Cameroon, Hong Kong, Portugal, Morocco, Hungary, Finland, Puerto Rico, Holy See (Vatican City State), Gabon, Bulgaria, Norway, Jamaica
DMEM (Dulbecco's Modified Eagle's Medium) is a cell culture medium formulated to support the growth and maintenance of a variety of cell types, including mammalian cells. It provides essential nutrients, amino acids, vitamins, and other components necessary for cell proliferation and survival in an in vitro environment.
8
Stereotaxic frame by Kopf Instruments
Sourced in United States, Germany, Italy
The Stereotaxic frame is a laboratory instrument used to immobilize and position the head of a subject, typically an animal, during surgical or experimental procedures. It provides a secure and reproducible method for aligning the subject's head in a three-dimensional coordinate system to enable precise targeting of specific brain regions.
9
Rnalater by Thermo Fisher Scientific
Sourced in United States, United Kingdom, Germany, Japan, Lithuania, Italy, Australia, Canada, Denmark, China, New Zealand, Spain, Belgium, France, Sweden, Switzerland, Brazil, Austria, Ireland, India, Netherlands, Portugal, Jamaica
RNAlater is a RNA stabilization solution developed by Thermo Fisher Scientific. It is designed to protect RNA from degradation during sample collection, storage, and transportation. RNAlater stabilizes the RNA in tissues and cells, allowing for efficient RNA extraction and analysis.
10
Dimethyl sulfoxide (dmso) by Merck Group
Sourced in United States, Germany, United Kingdom, China, Italy, Sao Tome and Principe, France, Macao, India, Canada, Switzerland, Japan, Australia, Spain, Poland, Belgium, Brazil, Czechia, Portugal, Austria, Denmark, Israel, Sweden, Ireland, Hungary, Mexico, Netherlands, Singapore, Indonesia, Slovakia, Cameroon, Norway, Thailand, Chile, Finland, Malaysia, Latvia, New Zealand, Hong Kong, Pakistan, Uruguay, Bangladesh
DMSO is a versatile organic solvent commonly used in laboratory settings. It has a high boiling point, low viscosity, and the ability to dissolve a wide range of polar and non-polar compounds. DMSO's core function is as a solvent, allowing for the effective dissolution and handling of various chemical substances during research and experimentation.

More about "Lidocaine"

Lidocaine is a widely used local anesthetic and antiarrhythmic drug that works by blocking sodium channels, preventing the propagation of action potentials and reducing the excitability of nerves.
It is commonly administered topically, intravenously, or as an injectable to provide pain relief and control cardiac arrhythmias.
Researching the optimal use of this versatile medication is crucial for various medical applications, from pain management to cardiac care.
Synonyms and related terms for Lidocaine include Xylocaine, SCAA-104, and the veterinary anesthetic Rompun.
Other key subtopics and terms to consider in Lidocaine research include FBS (fetal bovine serum), DMEM (Dulbecco's Modified Eagle Medium), stereotaxic frames for precise drug delivery, RNAlater for RNA preservation, and DMSO (dimethyl sulfoxide) as a common solvent.
PubCompare.ai is an AI-powered platform that can streamlane your Lidocaine research by easily locating relevant protocols from literature, pre-prints, and patents, and providing AI-driven comparisons to identify the best protocols and products for your needs.
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