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Methyl iodide

Methyl iodide (CH3I) is a highly reactive organic compound used in a variety of chemical syntheses and industrial processes.
It serves as a versatile alkylating agent, finding applications in the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
Methyl iodide is also used as a soil fumigant and as a laboratory reagent.
Researchers must carefully optimize protocols to ensure accurate and reproducible results when working with this potent substance.
PubCompare.ai can help identify the most effective and reliable methods from the scientific literature, pre-prints, and patents, leveraging AI-driven comparisons to enhance the quality of Methyl iodide studies.
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Most cited protocols related to «Methyl iodide»

Synthesis of TMAB-NHS Isotopic Tags

The overall reaction scheme is shown in Figure 1, and is described in detail below both in a standard protocol for chemists, as well as a less technical protocol intended for biochemists without formal training in organic chemistry. Additional notes on the synthesis are provided as supplemental information. All of the procedures involving organic solvents should be performed in a fume hood, and some of the reagents are especially toxic (methyl iodide and dicyclohexylcarbodiimide). Proper safety equipment should be used to handle these compounds and care should be taken to minimize exposure. The procedures described below are identical for all four isotopic tags; although the molecular weights and densities of the methyl iodide vary, the differences are so small as to be negligible. The use of CH₃I results in the production of D0-TMAB-NHS (Figure 2), which was previously referred to as H9-TMAB-NHS22 (link). The use of methyl iodide with 3 deuterium atoms in place of the hydrogen atoms (Cd₃I) produces D9-TMAB-NHS, as previously described 22 (link);23 (link). The two new labels are produced from CH₂dI and CHd₂I and result in the formation of D3-TMAB-NHS and D6-TMAB-NHS, respectively (Figure 2).

Morano C., Zhang X, & Fricker L.D. (2008). Multiple isotopic labels for quantitative mass spectrometry. Analytical chemistry, 80(23), 9298-9309.

Publication 2008

Deuterium Dicyclohexylcarbodiimide Isotopes methyl iodide Solvents Tritium

Arsenic Speciation in Urine Samples

The following commercial chemicals were used: ortho phosphoric acid (p.a., or TraceSELECT Ultra) from Fluka (Buchs, Switzerland); pyridine from Merck (Merck, Darmstadt, Germany); and hydrogen peroxide 30 % (p.a.), aqueous ammonia 25 % (suprapure), 65 % nitric acid (p.a.), and formic acid (p.a.) from Roth (Carl Roth, Karlsruhe, Germany). Chemicals were used without further purification except for the nitric acid which was distilled in a quartz sub-boiling distillation unit. Water used throughout was from a Milli-Q Academic water purification system (Millipore GmbH, Vienna, Austria) with a specific resistivity of 18.2 MΩ*cm.
Individual standard solutions (1000 ± 3 μg L⁻¹ in 2 % nitric acid) for total element determinations of As, Cd, Mo, Pb, Sb, Se, U, W, and Zn (in the urine samples) and Ge, In, and Lu (internal standards) were obtained from CPI International (Santa Rosa, CA, US). For arsenic speciation, stock solutions containing 1000 mg As L⁻¹ of each of the following species were prepared in water: arsenite (As(III) and arsenate (As(V)) prepared from NaAsO₂ and Na₂HAsO₄.7 H₂O, respectively, purchased from Merck (Darmstadt, Germany); dimethylarsinate (DMA) prepared from sodium dimethylarsinate purchased from Fluka (Buchs, Switzerland); methylarsonate (MA) prepared in-house from sodium arsenite and methyl iodide (Meyer reaction); and arsenobetaine (AB), as the bromide salt, prepared in-house following the method of Cannon et al.¹¹ The purity of the synthesized standards (MA and AB) was established by NMR and HPLC/mass spectrometry. Other arsenic standards (trimethylarsine oxide, arsenocholine, tetramethylarsonium ion, oxo and thio-dimethylarsinylethanol and oxo- and thio-dimethylarsinylacetic acid) were prepared as previously reported;^{12 ,13 (link)} these standards were used to check the identity of minor peaks which occasionally appeared in the chromatograms.
The certified reference materials for total element measurements were NIST 1643e, trace elements in water (National Institute of Standards & Technology, Gaithersburg, Maryland, US) certified for As, Cd, Mo, Pb, Sb, Se, & Zn; and NIES No. 18, human urine (National Institute for Environmental Studies, Tsukuba, Japan) certified for As, Se & Zn. In addition, Seronorm^™ control urine (Sero AS, Billingstad, Norway) and an in-house urine sample served as non-certified reference materials. The certified reference material for determining arsenic species was NIES No 18, human urine, certified for AB and DMA. Our in-house reference urine was used as a control for iAs, MA, DMA, and AB.

Scheer J., Findenig S., Goessler W., Francesconi K.A., Howard B., Umans J.G., Pollak J., Tellez-Plaza M., Silbergeld E.K., Guallar E, & Navas-Acien A. (2012). Arsenic species and selected metals in human urine: validation of HPLC/ICPMS and ICPMS procedures for a long-term population-based epidemiological study. Analytical methods : advancing methods and applications, 4(2), 406-413.

Publication 2012

Acids Ammonia arsenate Arsenic arsenite arsenobetaine arsenocholine Bromides Cacodylate Distillation formic acid High-Performance Liquid Chromatographies Homo sapiens Mass Spectrometry methylarsonate methyl iodide Nitric acid Peroxide, Hydrogen Phosphoric Acids pyridine Quartz Rosa Sodium sodium arsenite Sodium Chloride tetramethylarsonium Trace Elements trimethylarsine oxide Urine

Synthesis and Characterization of Hydrazine-Derived Compounds

Chemical synthesis of potential inhibitors. Reagents and solvents were from Aldrich, Alfa Aesar or Acros. Reactions were monitored by TLC, which was performed on precoated aluminum-backed plates (Merck, silica 60 F254). Melting points were determined using a Leica Galen III hot-stage melting point apparatus and microscope. Infrared spectra were recorded from Nujol mulls between sodium chloride discs, on a Bruker Tensor 27 FT-IR spectrometer. NMR spectra were acquired using a Bruker DPX500 NMR spectrometer. Chemical shifts (δ) are given in ppm, and the multiplicities are given as singlet (s), doublet (d), triplet (t), quartet (q), multiplet (m), broad (br). Coupling constants J are given in Hz (± 0.5 Hz). High resolution mass spectra (HRMS) were recorded using a Bruker MicroTOF spectrometer. The purity of all compounds synthesized were ≥95% as determined by analytical reverse-phase HPLC (Ultimate 3000). Daminozide (Alar^™) and compound 28 are commercially available. The synthesis and characterisation of compounds 22²⁵, 25^{26 (link)}, 27²⁷, 36²⁸, 37²⁹ and 38^{26 (link)} has been reported. The synthesis of compounds 31-35, 39-41 and ¹³C NMR spectra for 22, 23, 24, 26, 31-35 are given in the Supporting Information.
4-(2,2,2-Trimethylhydrazinyl)-4-oxobutanoate 22. The synthesis of compound 22 was as reported²⁵, thus reaction of daminozide (500mg, 3.1 mmol) with methyl iodide (700mg, 0.31 mL, 5.0 mmol) gave 22 as a white solid (75% yield), mp: 137-138 °C (lit.1 137-138.5 °C); ¹H NMR (500 MHz, MeOD): δ 2.40 (t, J = 6.5 Hz, 2H), 2.51 (t, J = 6.5 Hz, 2H), 3.56 (s, 9H); ¹³C NMR (125 MHz, MeOD): δ 28.5, 29.1, 56.1, 170.4, 173.4; IR (neat) υ/cm⁻¹: 3405, 3312, 1729, 1693; HRMS (m/z): [M]+ calcd. for C₇H₁₅N₂O₃, 175.1077; found, 175.1081.
General procedure for the coupling of hydrazine to succinic anhydride. To a stirred solution of the appropriate hydrazine (1 equiv.) in acetonitrile (5 mL) was added dropwise a solution of succinic anhydride (200 mg, 2.0 mmol, 1 equiv.) in acetonitrile (5 mL). The mixture was stirred at room temperature for 24 h, after which the solvent was evaporated in vacuo and the resulting crude purified using semipreparative reverse-phase HPLC, performed on a phenomenex C18 column (150 mm × 4.6 mm). Separation was achieved using a linear gradient of solvent A (water + 0.1% CF₃CO₂H) and solvent B (acetonitrile + 0.1% CF₃CO₂H), eluting at a flow rate of 1 mL/min and monitoring at 220 nm: 0% B to 40% B over 30 min.
4-(2-Methylhydrazinyl)-4-oxobutanoic acid 23. Compound 23 is a colourless oil (63% yield), ¹H NMR (500 MHz, DMSO-d6): δ 2.35 (t, J = 7.0 Hz, 2H), 2.68 (t, J = 7.0 Hz, 2H), 2.98 (s, 3H), 4.76 (s, 1H), 7.74 (s, 1H); ¹³C NMR (125 MHz, DMSO-d6): δ 28.3, 29.1, 170.1, 173.6; IR (neat) υ/cm⁻¹: 33 3219, 3057, 1708, 1632; HRMS (m/z): [M+Na]+ calcd. for C₅H₁₀N₂NaO₃, 169.0584; found, 169.0577.
4-Hydrazinyl-4-oxobutanoic acid 24. Compound 24 is a colourless oil (87% yield), ¹H NMR (500 MHz, DMSO-d6): δ 2.34 (t, J = 7.0 Hz, 2H), 2.60 (t, J = 7.0 Hz, 2H), 5.86 (s, 1H), 8.99 (s, 1H); ¹³C NMR (125 MHz, DMSO-d6): δ 28.2, 29.1, 170.8, 173.9; IR (neat) υ/cm⁻¹: 3303, 3290, 3199, 1712, 1624; HRMS (m/z): [M-H]- calcd. for C₄H₇N₂O₃, 131.0462; found, 131.0468.
4-Oxo-4-(1,2,2-trimethylhydrazinyl)butanoic acid 26. Compound 26 is a white solid (56% yield), mp: 97-98 °C, ¹H NMR (500 MHz, DMSO-d6): δ 2.37 (t, J = 7.0 Hz, 2H), 2.66 (t, J = 7.0 Hz, 2H), 2.74 (s, 3H), 11.98 (s, 1H); ¹³C NMR (125 MHz, DMSO-d6): δ 28.2, 29.8, 43.4, 48.7, 173.5, 175.0; IR (neat) υ/cm⁻¹: 2958, 1723, 1615; HRMS (m/z): [M+Na]+ calcd. for C₇H₁₄N₂NaO₃, 197.0897; found, 197.0895.
4-((Dimethylamino)oxy)-4-oxobutanoic acid 29. N,N-Dimethylhydroxylamine (39 mg, 0.63 mmol, 1.1 equiv. ) was added to a solution of 4-(tert-butoxy)-4-oxobutanoic acid (100 mg, 0.57 mmol, 1 equiv.), hydroxybenzotriazole (100 mg, 0.74 mmol, 1.3 equiv.), 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide ( 140 mg, 0.74 mmol, 1.3 equiv.) and diisopropylethylamine ( 0.2 mL, 1.14 mmol, 2.0 equiv.) in CH₂Cl₂ (10 mL). The reaction was stirred at room temperature overnight, washed with water, HCl 1N, brine, dried on MgSO₄. The organic phase was evaporated in vacuo and purified by chromatography (MeOH/CH₂Cl₂ 0.5/9.5) to obtain 110 mg of tert-butyl 4((dimethylamino)oxy)-4-oxobutanoate (90% yield). CF₃CO₂H (0.04 ml, 0.37 mmol, 4 equiv.) was added to a solution of tert-butyl 4((dimethylamino)oxy)-4-oxobutanoate (20 mg, 0.09 mmol, 1 equiv.) in CH₂Cl₂ (1.5 ml). The reaction was stirred at room temperature for 4h and evaporated in vacuo to give 14 mg of 29 (yield 95%). ¹H NMR (500 MHz, CD₃OD) δ 2.59 (s, 6H), 2.57 (s, 4H); ¹³C NMR (500 MHz, CD₃OD) δ 176.2, 172.0, 48.5, 29.9; IR (neat) 3341, 2485,1717, 1120, 1026, 975 cm⁻¹; HRMS (m/z):[M+]calcd. for C₆H₁₁NO₄ 161.0688; found 161.0923.
N‘1, N‘1, N‘4, N‘4-Tetramethylsuccinohydrazide 30. A solution of succinic acid (100 mg, 0.85 mmol, 1 equiv.), hydroxybenzotriazole (350 mg, 2.11 mmol, 2.3 equiv.), 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (421 mg, 2.11 mmol, 2.3 equiv.), diisopropylethylamine (0.6 mL, 3.4 mmol, 4 equiv.) and 1,1-dimethylhydrazine (0.16 mL, 2.04 mmol, 2.2 equiv.) in CH₂Cl₂ (20 mL) was stirred at room temperature overnight. CH₂Cl₂ (10 mL) was added and the reaction mixture was washed with water, a saturated solution of NaHCO₃, brine and dried on MgSO₄. The organic phase was evaporated in vacuo and purified by chromatography (MeOH/ CH₂Cl₂ 1/9) to give 77 mg of 30 (45% yield). ¹H NMR (500 MHz, CD₃OD) δ 2.87 (s, 6H), 2.65 (s, 2H); ¹³C NMR (500 MHz, CD₃OD) δ 178.2, 43.8, 27.6; IR (neat) 3356, 2485, 2071, 1695, 1120, 1027, 974 cm⁻¹; HRMS (m/z):[(M-2CH3)⁻]calcd. for C₆H₁₄N₄O₂, 174.1117; found, 174.1022.

Rose N.R., Woon E.C., Tumber A., Walport L.J., Chowdhury R., Li X.S., King O.N., Lejeune C., Ng S.S., Krojer T., Chan M.C., Rydzik A.M., Hopkinson R.J., Che K.H., Daniel M., Strain-Damerell C., Gileadi C., Kochan G., Leung I.K., Dunford J., Yeoh K.K., Ratcliffe P.J., Burgess-Brown N., von Delft F., Muller S., Marsden B., Brennan P.E., McDonough M.A., Oppermann U., Klose R.J., Schofield C.J, & Kawamura A. (2012). The Plant Growth Regulator Daminozide is a Selective Inhibitor of the Human KDM2/7 Histone Demethylases. Journal of medicinal chemistry, 55(14), 6639-6643.

Publication 2012

Fatty acid derivatization and LC-MS analysis

Chemicals, reagents, standards preparation, and fatty acids extraction from red blood cells (RBC) information is provided in supplemental notes in the Supporting Information. Both the FA standards and RBC samples underwent the same extraction, hydrolysis, and derivatization steps before LC–MS analysis. The derivatization procedure was modified from Johnson’s method.⁹ In brief, 150 μL of standard (0.1–100 μg/mL) and 20 μL of internal standard mixture were mixed and dried under nitrogen. To the dried residue was added 200 μL of oxalyl chloride (2 M in dichloromethane), and the mixture was incubated at 65 °C on a heating block for 5 min and then dried under nitrogen. To the residue was added 150 μL of dimethylaminoethanol, 3-picolylamine, or 3-pyridylcarbinol, respectively (1% in acetonitrile, v/v) to form the dimethylaminoethyl ester (FA-DMAE), 3-picolylamide (FA-PA), and 3-picolinyl ester (FA-PE) derivatives (Figure 1), respectively. The mixture was incubated at room temperature for 5 min, followed by drying under nitrogen to give the derivatized FAs. The FA-DMAE product was further converted to trimethylaminoethyl ester (FA-TMAE) by incubating with 150 μL of methyl iodide (50% in methanol, v/v) at room temperature for 5 min, followed by drying under nitrogen. The dried FAs derivatives were dissolved in 1000 μL of ethanol and further diluted up to 10-fold with ethanol prior to LC–MS analysis.

Li X, & Franke A.A. (2011). Improved LC–MS Method for the Determination of Fatty Acids in Red Blood Cells by LC–Orbitrap MS. Analytical chemistry, 83(8), 3192-3198.

Publication 2011

acetonitrile Deanol derivatives Erythrocytes Esters Ethanol Fatty Acids Hydrolysis Methanol Methylene Chloride methyl iodide Nicotinyl Alcohol Nitrogen oxalyl chloride Standard Preparations

Quantification of Plasma Carnitine and Derivatives

Matching CID spectra of an unknown plasma metabolite with identical retention time and mass-to-charge ratio (m/z) as authentic L-carnitine (m/z = 162) were obtained as described in Supplementary Methods. Concentrations of carnitine, TMA and TMAO isotopologues in mouse and human plasma samples were determined by stable isotope dilution LC/MS/MS in positive MRM mode using deuterated internal standards on an AB Sciex API 5000 triple quadrupole mass spectrometer (Applied Biosystems) as described in Supplementary Methods. In studies quantifying endogenous carnitine and ingested d3-carnitine, d9-carnitine was used as internal standard. D9-carnitine was prepared by dissolving 3-hydroxy-4-aminobutyric acid (Chem-Impex Intl.) in methanol and exhaustive reaction with d3-methyl iodide (Cambridge Isotope Labs) in the presence of potassium hydrogen carbonate. Further details regarding synthesis, purification and characterization of d9-carnitine can be found in Supplementary Methods.

Koeth R.A., Wang Z., Levison B.S., Buffa J.A., Org E., Sheehy B.T., Britt E.B., Fu X., Wu Y., Li L., Smith J.D., DiDonato J.A., Chen J., Li H., Wu G.D., Lewis J.D., Warrier M., Brown J.M., Krauss R.M., Tang W.H., Bushman F.D., Lusis A.J, & Hazen S.L. (2013). Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nature medicine, 19(5), 576-585.

Publication 2013

Aminobutyric Acid Anabolism Carnitine Homo sapiens Isotopes Methanol methyl iodide Mice, House Plasma potassium bicarbonate Retention (Psychology) Tandem Mass Spectrometry Technique, Dilution trimethyloxamine

Most recents protocols related to «Methyl iodide»

Dynamic Adsorption of Methyl Iodide

Dynamic adsorption experiments were executed utilizing a laboratory-scale fixed-bed reactor operating at a temperature of 150 °C. Specifically, 30 mg of adsorbent was loaded into a quartz column (4.6 mm I.D. × 200 mm) with silane-treated glass wool employed to occupy the interstitial void space. The column was subsequently activated at 150 °C for 6 h under a dry helium flow (10 mL/min). To evaluate performance under a partial pressure of 0.2 bar, a nitrogen carrier flow at a rate of 3 mL/min was directed through a CH₃I vapor generator, subsequently passing through the adsorbent-packed column at a linear velocity of 18 cm/min, corresponding to a residence time of approximately 5 s. The concentration of CH₃I in the effluent was continuously monitored using an online mass spectrometry (MS) system. The flow rate of CH₃I under these conditions was determined to be approximately 4.408 mg/min by trial and error.
To assess performance under a partial pressure of 0.01 bar, a nitrogen carrier flow at a rate of 0.3 mL/min was directed through the CH₃I vapor generator, subsequently combined with another dry nitrogen flow at a rate of 5.7 mL/min before passing through the adsorbent column. Under these conditions, the linear velocity was 36 cm/min, with a residence time of ~2.5 s. The flow rate of CH₃I under this configuration was approximately 0.426 mg/min. Experiments conducted under humid conditions (RH = 50%) at 0.01 bar involved mixing a nitrogen flow passing through the CH₃I vapor generator at a rate of 0.3 mL/min with a nitrogen flow passing through the water vapor generator at a rate of 3 mL/min, along with a dry nitrogen flow at a rate of 2.7 mL/min. The combined gas stream was then directed through the adsorbent column. Monitoring of CH₃I in the effluent was performed using an online MS system.
The adsorption capacities at breakthrough (Q_breakthrough) were determined using the following equation:

Q_{b r e a k t h r o u g h} = \frac{v \times t_{1 %}}{m} 1

Where v represents the flow rate of CH₃I (mg/min); t_1% (corresponding to C/C₀ = 1%, min) denotes the breakthrough point when the concentration of CH₃I in the effluent stream (C) reaches 1% of the initial concentration (C₀); m signifies the weight of the adsorbent (mg).

Pan T., Yang K., Dong X., Zuo S., Chen C., Li G., Emwas A.H., Zhang H, & Han Y. (2024). Strategies for high-temperature methyl iodide capture in azolate-based metal-organic frameworks. Nature Communications, 15, 2630.

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Publication 2024

Automated Radiosynthesis of [11C]CH3I

[¹¹C]CH₄ was produced from a methane target via the ¹⁴N(p, α)¹¹C nuclear reaction in a cyclotron. The target was filled with nitrogen gas mixed with 10% hydrogen and bombarded for 2–5 min at 35 µA. [¹¹C]CH₃I was synthesized using the TracerMaker module with in-target-produced [¹¹C]CH₄ as previously reported [30 (link)]. After the production of [¹¹C]CH₃I (~3–5.5 GBq), it was transferred through a separate line directly connected to the iMiDEV™ radiosynthesizer. The flow rate of [¹¹C]CH₃I was set at 8 mL/min [24 (link)].

Mallapura H., Tanguy L., Mahfuz S., Bylund L., Långström B., Halldin C, & Nag S. (2024). Advancements in Microfluidic Cassette-Based iMiDEV™ Technology for Production of L-[11C]Methionine and [11C]Choline. Pharmaceuticals, 17(2), 250.

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Publication 2024

Synthesis of Substituted Acetamides

A mixture of 1 (3.95 g, 10 mmol), methyl iodide (0.7 mL, 10 mmol), ethyl chloroacetate (1 mL, 10 mmol), 2-chloroacetamide (0.93 g, 10 mmol), chloroacetonitrile (0.8 mL, 10 mmol)or N-aryl-2-chloroacetamide 2a–e (10 mmol), and sodium acetate trihydrate (1.50 g, 11 mmol) in ethanol (100 mL) was refluxed for one hour. The reaction mixture was then allowed to stand at room temperature overnight. After that the precipitate was collected and recrystallized from ethanol as colorless crystals of title compounds 3, 4, 5, 6, and 7a–e respectively.

Sayed E.M., Bakhite E.A., Hassanien R., Farhan N., Aly H.F., Morsy S.G, & Hassan N.A. (2024). Novel tetrahydroisoquinolines as DHFR and CDK2 inhibitors: synthesis, characterization, anticancer activity and antioxidant properties. BMC Chemistry, 18(1), 34.

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Publication 2024

Quaternization of Poly(4-vinylpyridine)

P4VP was quaternized according
to an adapted procedure from Sadman and co-workers.^{39 (link)} To obtain QP4VP, 4.00 g (38 mmol) of P4VP was dissolved
in 40 mL of DMSO before 10.8 g (76 mmol, 2 equiv) of MeI was added
dropwise, and the reaction was stirred for 4 h at room temperature.
Excess MeI was first removed by bubbling the solution with nitrogen
before precipitation was performed in acetone, and the polymer was
redissolved in water. QP4VP was retrieved after freeze-drying and
with high yield, i.e., quaternization ≥99%, 9.06 g (yield 96%)
(Figure S6).

van Westerveld L., Pelras T., Hofman A.H., Loos K., Kamperman M, & Es Sayed J. (2024). Effect of Polyelectrolyte Charge Density on the Linear Viscoelastic Behavior and Processing of Complex Coacervate Adhesives. Macromolecules, 57(2), 652-663.

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Publication 2024

Fabrication of Perovskite Solar Cells

F-doped tin oxide (FTO) glass substrate (8 Ω per square) was purchased from Suzhou Shangyang Solar Energy Technology Co. Ltd. Formamidine hydroiodate (FAI), methyl ammonium iodide (MAI), cesium iodide (CsI), methyl ammonium chloride (MACl), and 2,2′,7,7′-tetrakis(N,N-di-p-methoxyphenylamine)-9,9′-spirobifluorene (spiro-MeOTAD) were purchased from Liaoning Optimum New Energy Technology Co. Ltd. Lead iodide (PbI₂), lead bromide (PbBr₂), and isopropanol (IPA) were purchased from TCI. Phenethylmethoxy iodide (PEAI), bistrifluoromethanesulfonimide lithium salt (Li-TFSI), 4-tert-butylpyridine (t-BP), and tris(2-(1H-pyrazol-1-yl)-4-tert-butylpyridine)-cobalt(III)-tris(bis-(trifluoromethylsulfonyl)imide) (FK-209) were purchased from Xi’an Yuri Solar Co. Ltd. Titanium tetrachloride (TiCl₄), dimethylformamide (DMF), dimethyl sulfoxide (DMSO), acetonitrile (ACN), and chlorobenzene (CB) were purchased from Sigma-Aldrich.

Wang X., Wang M., Zhang Z., Wei D., Cai S., Li Y., Zhang R., Zhang L., Zhang R., Zhu C., Huang X., Gao F., Gao P., Wang Y, & Huang W. (2024). De Novo Design of Spiro-Type Hole-Transporting Material: Anisotropic Regulation Toward Efficient and Stable Perovskite Solar Cells. Research, 7, 0332.

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Publication 2024

Top products related to «Methyl iodide»

Dimethyl sulfoxide (dmso) by Merck Group

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Propidium iodide by Merck Group

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Propidium iodide is a fluorescent dye used in flow cytometry to stain and quantify DNA content in cells. It binds to DNA by intercalating between the bases. Propidium iodide is commonly used to distinguish viable from non-viable cells.

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Potassium iodide is a chemical compound that is commonly used in laboratory settings. It is a white, crystalline solid that is soluble in water and has a wide range of applications in various industries, including pharmaceuticals, photography, and water treatment. The core function of potassium iodide is to serve as a source of iodide ions, which are essential for various chemical reactions and processes.

Acetonitrile by Merck Group

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Acetonitrile is a colorless, volatile, flammable liquid. It is a commonly used solvent in various analytical and chemical applications, including liquid chromatography, gas chromatography, and other laboratory procedures. Acetonitrile is known for its high polarity and ability to dissolve a wide range of organic compounds.

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Methanol is a clear, colorless, and flammable liquid that is widely used in various industrial and laboratory applications. It serves as a solvent, fuel, and chemical intermediate. Methanol has a simple chemical formula of CH3OH and a boiling point of 64.7°C. It is a versatile compound that is widely used in the production of other chemicals, as well as in the fuel industry.

What are some common challenges researchers face when working with Methyl iodide?

Methyl iodide is a highly reactive and potent substance, which can present several challenges for researchers. Proper safety protocols must be followed to handle it, as exposure can be hazardous. Additionally, achieving accurate and reproducible results when using Methyl iodide in experiments can be difficult, as slight variations in protocols can lead to significant differences in outcomes. Carefully optimizing experimental procedures is crucial to ensure reliable and consistent data.

How can PubCompare.ai help researchers working with Methyl iodide?

PubCompare.ai is a powerful tool that can assist researchers in optimizing their Methyl iodide studies. The platform allows you to efficiently screen protocol literature, leveraging AI to pinpoint critical insights. By comparing Methyl iodide protocols from the scientific literature, pre-prints, and patents, PubCompare.ai can help you identify the most effective and reliable methods for your specific research goals. The AI-driven analysis can highlight key differences in protocol effectiveness, enabling you to choose the best option for reproducibility and accuracy in your Methyl iodide experiments.

Are there different types or variations of Methyl iodide?

Yes, there are several variations and applications of Methyl iodide. In addition to its use as a chemical reagent, Methyl iodide is also employed as a soil fumigant, which involves injecting the compound into the soil to control pests and pathogens. Morever, Methyl iodide finds applications in the production of pharmaceuticals, agrochemicals, and other specialty chemicals, where it serves as a versatile alkylating agent. Depending on the specific research or industrial application, the required purity, handling, and safety protocols for Methyl iodide may vary.

What are some common applications of Methyl iodide?

Methyl iodide has a wide range of applications in the chemical and pharmaceutical industries. It is commonly used as a reagent in organic synthesis, partcularly in the production of pharmaceuticals and agrochemicals. Methyl iodide also serves as a soil fumigant, helping to control pests and pathogens in agricultural settings. Additionally, it is employed as a labortory reagent for a variety of experements and analytical procedures. The versitility of Methyl iodide makes it an important chemical for many industrial and research applications.

More about "Methyl iodide"

DMSO, Propidium iodide, Methyl iodide, Sodium hydroxide, FBS, Chlorobenzene, Potassium iodide, Acetonitrile, Methanol