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Nitroglycerin

Nitroglycerin is a potent vasodilator used in the treatment of angina pectoris, heart failure, and other cardiovascular conditions.
It acts by relaxing vascular smooth muscle, leading to decreased peripheral vascular resistance and improved blood flow.
Nitroglycerin can be administered sublingually, transdermally, or intravenously, and its effects are typically rapid in onset but short-lived.
Careful dosing is required to avoid adverse effects such as headache, hypotension, and methemoglobinemia.
Nitroglycerin research is an important area of study, with researchers using advanced techniques like AI-driven protocols to ensure exceptional reproducibility and accuracy.
PubCompare.ai offers a cutting-edge solution for finding the best Nitroglycerin research protocols and products from literature, preprints, and patents, helping to take Nitroglycerin experiments to new heights.

Most cited protocols related to «Nitroglycerin»

1
MASALA Study Eligibility Criteria
Cited 60 times
To be eligible for the MASALA study participants had to have (1) South Asian ancestry defined by having at least 3 grandparents born in one of the following countries: India, Pakistan, Bangladesh, Nepal, or Sri Lanka; and (2) age between 40 and 79 years; (3) ability to speak and/or read English, Hindi or Urdu. A pilot study called the Metabolic syndrome and Atherosclerosis in South Asians Living in America (NIH grant #K23 HL080026) had similar eligibility criteria and methods as this larger study. The 150 participants enrolled in the pilot study were eligible to enroll in the current MASALA study.
We used identical exclusion criteria to MESA12 (link) which included having a physician diagnosed heart attack, stroke or transient ischemic attack, heart failure, angina, use of nitroglycerin, or those with a history of cardiovascular procedures such as coronary artery bypass graft surgery, angioplasty, valve replacement, pacemaker or defibrillator implantation, or any surgery on the heart or arteries. Those with current atrial fibrillation or in active treatment for cancer were excluded. Those with life expectancy < 5 years due to a serious medical illness, impaired cognitive ability as judged by the reviewer, plans to move out of the study region in the next 5 years, or those living in a nursing home or on a waiting list were also excluded. Due to CT scanner limitations, those weighing over 300 lbs. were excluded.
Kanaya A.M., Kandula N., Herrington D., Budoff M.J., Hulley S., Vittinghoff E, & Liu K. (2013). Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study: Objectives, Methods, and Cohort Description. Clinical Cardiology, 36(12), 713-720.
Publication 2013
Angina Pectoris Angioplasty Arteries Asian Persons Atherosclerosis Atrial Fibrillation Cardiovascular System CAT SCANNERS X RAY Cerebrovascular Accident Childbirth Cognition Congestive Heart Failure Coronary Artery Bypass Surgery Defibrillators Eligibility Determination Grandparent Infantile Neuroaxonal Dystrophy Malignant Neoplasms Metabolic Syndrome X Myocardial Infarction Nitroglycerin Ovum Implantation Pacemaker, Artificial Cardiac Physicians South Asian People Surgical Procedure, Cardiac Transient Ischemic Attack
2
Nitroglycerin-Induced Hyperalgesia in Mice
Cited 38 times

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Publication 2013
Animals Central Nervous System Ethanol Hypersensitivity Injections, Intraperitoneal Intrathecal Injection Lumbar Region Mice, House Needles Nitroglycerin Normal Saline Pharmaceutical Preparations Propylene Glycol Sumatriptan Topiramate
3
HIV-1 Viral Suppression and Mesalamine
Cited 8 times
Enrolled subjects on continuous suppressive ART were randomized to receive either mesalamine or matching placebo for 12 weeks, followed by a 12 week crossover period on the alternative arm. The primary outcome was the change in the percent activated (CD38+ HLA-DR+) CD8+ T cells at week 12. Consenting subjects also participated in a serial rectal biopsy sub-study to evaluate the effects of mesalamine in the GALT.
Subjects were recruited from the University of California, San Francisco [UCSF] between February, 2011 and June, 2012 with the last date of follow-up occurring in December, 2012. Chronically HIV-infected adults maintaining plasma HIV RNA levels below the limit of detection of the locally available clinical threshold for ≥1 year on stable ART and with persistent CD4+ T cell counts <350 cells/mm3 were eligible. Detectable episodes of viremia <500 copies/ml were allowed in the prior year if they were flanked by confirmed undetectable values. Patients were ineligible if they experienced an increase in CD4+ T cell count >100 cells/mm3 in the last year; reported <90% adherence to ART; had any serious acute illness in the preceding 3 months; were pregnant or breastfeeding; or had any of the following laboratory abnormalities: absolute neutrophil count <1,000 cells/mm3, platelet count <50,000 cells/mm3, hemoglobin <8 mg/dL, creatinine clearance <40 mL/minute, or serum transaminases >2.5x the upper limit of normal. For the endothelial function studies, as nitroglycerin is administered, any Viagra-like drug within 72 hours of the study was prohibited. Changes in doses of lipid lowering medication or anti-hypertensive medication were also not permitted less than 90 days prior to study entry or during the study.
The study was approved by the institutional review board at UCSF and all subjects provided written informed consent (IRB #: 10–010123; Clinical Trials #: NCT01090102). The protocol for this trial and supporting checklist are available as S1 Protocol and S1 CONSORT Checklist.
Somsouk M., Dunham R.M., Cohen M., Albright R., Abdel-Mohsen M., Liegler T., Lifson J., Piatak M., Gorelick R., Huang Y., Wu Y., Hsue P.Y., Martin J.N., Deeks S.G., McCune J.M, & Hunt P.W. (2014). The Immunologic Effects of Mesalamine in Treated HIV-Infected Individuals with Incomplete CD4+ T Cell Recovery: A Randomized Crossover Trial. PLoS ONE, 9(12), e116306.
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Publication 2014
Adult Antihypertensive Agents Biopsy CD4 Positive T Lymphocytes CD8-Positive T-Lymphocytes Cells Congenital Abnormality Creatinine Endothelium Hemoglobin HLA-DR Antigens Lipids Mesalamine Neutrophil Nitroglycerin Patients Pharmaceutical Preparations Placebos Plasma Platelet Counts, Blood Rectum Serum Transaminases Viagra Viremia
4
MESA Subclinical Atherosclerosis Protocol
Cited 7 times
MESA is a prospective cohort study investigating subclinical atherosclerosis in 6814 individuals aged 45–84 years without known clinical CVD at baseline. Women made up 53% of the cohort and four ethnic groups were represented; 38% Caucasian, 28% African American, 22% Hispanic, and 12% Chinese. The cohort was recruited and initially examined from 2000–2002 at six field centers: Baltimore, MD; Chicago, IL; Los Angeles, CA; New York, NY; St Paul, MN; and Winston-Salem, NC. Individuals were excluded if they had clinical CVD, including physician-diagnosed myocardial infarction, angina, stroke, transient ischemic attack, or heart failure, use of nitroglycerin, current atrial fibrillation, or had undergone a procedure related to CVD. A detailed description of the study design, recruitment methods, examination components, and data collection has been published9 (link).
After the MESA study began an ancillary study measured AAC and CAC at the same examination in a random sample of MESA participants, recruited during follow-up visits between August 2002 and September 2005 from five of the six MESA field centers: those above with the exception of Baltimore, MD. Of 2202 MESA participants recruited, 2172 agreed to participate, and 1990 satisfied eligibility criteria. 1974 participants had complete CT scanning of their abdominal aorta. Further details about the MESA study design have been published elsewhere and are available on at www.mesa-nhlbi.org.
Criqui M., Kamineni A., Allison M., Ix J., Carr J., Cushman M., Detrano R., Post W, & Wong N. (2010). Risk Factor Differences for Aortic vs. Coronary Calcified Atherosclerosis: the Multi-Ethnic Study of Atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology, 30(11), 2289-2296.
Publication 2010
African American Angina Pectoris Aortas, Abdominal Atherosclerosis Atrial Fibrillation Caucasoid Races Cerebrovascular Accident Chinese Congestive Heart Failure Eligibility Determination Ethnic Groups Hispanics Myocardial Infarction Nitroglycerin Physicians Transient Ischemic Attack Woman
5
Coronary CT Angiography Protocol
Cited 7 times

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Publication 2009
Adrenergic beta-Antagonists Artery, Coronary CAT SCANNERS X RAY Contrast Media Heart Inhalation Metoprolol Nitroglycerin Patients Radionuclide Imaging Rate, Heart Reconstructive Surgical Procedures Systolic Pressure Visipaque

Most recents protocols related to «Nitroglycerin»

1
Nitroglycerin-Induced Migraine Alleviation
Not available on PMC !

Example 6

A 42-year-old male subject ingested 5 mg (2 capsules) of sustained release nitroglycerin (Supranitrin, GAP. A.E., Greece) and developed a migraine 30 minutes later. The migraine continued for over two hours. After a 3-day washout period, the subject ingested 5 mg (2 capsules) of sustained release nitroglycerin with 200 mg elemental magnesium powder (60-200 mesh size). Although the subject felt lightheaded after ingesting the combination of sustained release nitroglycerin and elemental magnesium, he did not develop a migraine from ingestion of the nitroglycerin.

US11865139B2. Method of treating migraines and headaches (2024-01-09). ThermoLife International, LLC [US]. Inventors: Ronald Kramer [US], Alexandros Nikolaidis [GR].
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Patent 2024
Capsule Feelings Headache Magnesium Males Migraine Disorders Nitroglycerin Powder
2
Measuring Vascular Endothelial Function
Flow-mediated vasodilation was measured as endothelium-dependent vasodilation of vascular response to reactive hyperemia in the brachial artery by using an automated edge detection system (UNEXEF18G, UNEX Co, Nagoya, Japan) (26 (link)). NID was measured in vascular response to nitroglycerine as endothelium-independent vasodilation, as previously reported (26 (link)). This study was conducted with a methodological approach to FMD, following the recommendations proposed by Thijssen et al. (27 (link)). Additional details can be found in the Supplementary material.
Kishimoto S., Oda N., Maruhashi T., Tanigawa S., Mizobuchi A., Yusoff F.M., Fujita A., Uchiki T., Kajikawa M., Yoshimura K., Yamaji T., Harada T., Hashimoto Y., Nakano Y., Hirota S., Yoshinaga S., Goto C., Nakashima A, & Higashi Y. (2023). Effect of exposure to radiation caused by an atomic bomb on endothelial function in atomic bomb survivors. Frontiers in Cardiovascular Medicine, 10, 1122794.
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Publication 2023
Blood Vessel Brachial Artery Conditioning, Classical Endothelium Nitroglycerin Reactive Hyperemia Vasodilation
3
Cardiac CT Imaging for Plaque Analysis
Non-contrast cardiac CT and coronary CT angiography were performed using a 256-slice CT scanner (Brilliance iCT; Philips Healthcare, Best, The Netherlands). Prior to CT, participants were given 50 to 75 mg of metoprolol orally if heart rate was >60 beats/min, and 0.4 mg of nitroglycerin sublingually unless contraindicated.
Non-contrast cardiac CT was performed for coronary calcium scoring and EF evaluation using the following parameters: slice thickness 2.5 mm, matrix 512 × 512, field-of-view 250 mm, scan voltage 120 kV and prospective electrocardiographic-gating. CT angiography was performed for coronary plaque analysis using 370 mg/mL of iopamidol (Bracco Imaging, Milan, Italy) at a flow rate of 5 mL/s. Images were reconstructed using a hybrid iterative reconstruction algorithm (Philips iDose; Philips Healthcare, level 3).
Sadouni M., Duquet-Armand M., Alkeddeh M.G., El-Far M., Larouche-Anctil E., Tremblay C., Baril J.G., Trottier B., Chartrand-Lefebvre C, & Durand M. (2023). Epicardial fat density, coronary artery disease and inflammation in people living with HIV. Medicine, 102(9), e32980.
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Publication 2023
Calcium, Dietary CAT SCANNERS X RAY Computed Tomography Angiography Coronary Angiography Dental Plaque Electrocardiography Heart Hybrids idose Iopamidol Metoprolol Nitroglycerin Radionuclide Imaging Rate, Heart Reconstructive Surgical Procedures
4
Nitroglycerine and Metoprolol for Cardiac Examination
All patients provided a written informed consent before participating in the study. Heart rate and blood pressure were measured at rest before the examination. Patients with a heart rate of > 70 bpm were given metoprolol (Betaloc, 25-100 mg). These patients were randomly assigned into two groups (groups A1 and A2) at a ratio of 2:1. Before the examination, these patients were administered with 0.5 mg nitroglycerine tablets.
Hu X.L., Huang P.K., Zhang M., Chen J, & Xiao M.Q. (2023). Effects of combining multiple dose reduction techniques on coronary computed tomography angiography. World Journal of Radiology, 15(2), 32-41.
Publication 2023
Betaloc Blood Pressure Metoprolol Nitroglycerin Patients Rate, Heart
5
Interactive Virtual Simulation Software
We developed the IVS software in Unity 3D using the C# programming language [13 ]. The IVS software requires 2 monitors to be connected to the computer. One monitor displays a dashboard of buttons that are used by the facilitator to control the simulation content displayed on the second monitor. The dashboard is viewed only by the facilitator, and the second monitor displaying the content is viewed by the students. Each button on the dashboard corresponds to one piece of multimedia content, such as a video clip, image, or text. When a button is clicked on the dashboard, the corresponding content is displayed on the students’ monitor. The dashboard enables content to be displayed on the students’ monitor seamlessly and in any order. The multimedia content is imported into the software before the simulation. The software stores the content information and button data (eg, labels, colors, and order) in csv files. These files can be modified to assign content to buttons and to change the layout and design of the dashboard. During the simulation, the facilitator provides students with a Scenario, Background, Assessment, and Recommendation (SBAR) and asks them to describe the steps of the patient care. As the students describe their patient care, the facilitator displays the associated multimedia content on the students’ screen. For example, if students explain that they want to administer nitroglycerin medication, the facilitator will play the video clip of a nurse administering the medication. If students want to review the patient’s electrocardiogram, the facilitator will display an image of the electrocardiogram. When a button is clicked, the data are written to a log that the facilitator can later review to evaluate students’ performance.
The IVS software can be used to conduct a simulation locally or remotely. In a remote simulation, the facilitator connects with students via a videoconferencing application. The facilitator then uses the screen sharing feature to allow students to view the monitor displaying the simulation content, whereas the other monitor displaying the dashboard remains visible only to the facilitator. In this study, the simulation was controlled locally without the use of a videoconferencing application or the internet. In a previous study, we used the IVS software to conduct a remote simulation over Zoom [12 (link),14 ]. We found that streaming videos over Zoom caused a reduction in the frame rate, and the videos lagged on the students’ screens. Many students reported that the lagging videos were distracting to their learning experiences [12 (link)]. In this study, the simulation was conducted locally without the internet to eliminate this factor, allowing us to focus exclusively on interactivity.
Musa D., Gonzalez L., Penney H, & Daher S. (2023). Technology Acceptance and Authenticity in Interactive Simulation: Experimental Study. JMIR Medical Education, 9, e40040.
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Publication 2023
Clip Electrocardiogram Nitroglycerin Nurses Patients Pharmaceutical Preparations Reading Frames Student

Top products related to «Nitroglycerin»

1
Somatom force by Siemens
Sourced in Germany, United States, Japan
The SOMATOM Force is a high-performance computed tomography (CT) system developed by Siemens. It is designed to deliver fast, precise, and efficient imaging capabilities for a wide range of clinical applications. The SOMATOM Force features advanced technologies that enable high-quality imaging while minimizing radiation exposure.
2
Brilliance ict by Philips
Sourced in United States, Netherlands, Germany, Japan, Israel
The Brilliance iCT is a computed tomography (CT) imaging system developed by Philips. It is designed to capture high-quality, three-dimensional images of the body for medical diagnostic purposes. The Brilliance iCT utilizes advanced imaging technology to provide detailed visualization of anatomical structures, enabling healthcare professionals to make informed decisions about patient care.
3
Somatom definition flash by Siemens
Sourced in Germany, United States, Japan, Netherlands, United Kingdom
The SOMATOM Definition Flash is a computed tomography (CT) scanner developed by Siemens. It is designed to provide high-quality imaging for a wide range of medical applications. The SOMATOM Definition Flash utilizes advanced technology to capture detailed images of the body, enabling medical professionals to make accurate diagnoses and inform treatment decisions.
4
Iomeron 400 by Bracco
Sourced in Italy, Germany, United Kingdom
Iomeron 400 is a non-ionic iodinated contrast medium used for medical imaging procedures. It is designed to enhance the visibility of internal structures during diagnostic imaging tests.
5
Somatom definition by Siemens
Sourced in Germany, United States, Japan, Netherlands
The Somatom Definition is a computed tomography (CT) scanner developed by Siemens. It is a diagnostic imaging device that uses X-rays to create detailed cross-sectional images of the body.
6
Aquilion one by Toshiba
Sourced in Japan, Germany, United States
The Aquilion ONE is a computed tomography (CT) scanner developed by Toshiba. It is capable of performing whole-body scans in a single rotation, allowing for faster and more comprehensive imaging. The Aquilion ONE utilizes advanced technology to capture high-quality images, but a detailed description of its core function is not available without extrapolation or interpretation.
7
Brilliance 64 by Philips
Sourced in United States, Netherlands, Germany, Japan, United Kingdom
The Philips Brilliance 64 is a computed tomography (CT) imaging system designed for medical diagnostic purposes. It features a 64-slice detector configuration, enabling rapid data acquisition and high-resolution imaging. The Brilliance 64 provides detailed anatomical information to support clinical decision-making for a variety of medical applications.
8
Atlantis sr pro by Boston Scientific
Sourced in United States
The Atlantis SR Pro is a lab equipment product designed for research and development purposes. It serves as a platform for performing various scientific experiments and analyses. The core function of the Atlantis SR Pro is to provide a controlled and stable environment for conducting these research activities.
9
Nitroglycerin by Merck Group
Sourced in United States
Nitroglycerin is a chemical compound used as a reagent in analytical and synthetic laboratory applications. It functions as an oxidizing agent and is commonly employed in various chemical reactions and analytical procedures.
10
Ultravist 370 by Bayer
Sourced in Germany, United States, Italy, United Kingdom, Switzerland
Ultravist 370 is a non-ionic, water-soluble contrast medium used for radiographic examinations. It contains the active ingredient iopromide and has a concentration of 370 mg iodine per milliliter.

More about "Nitroglycerin"

Glyceryl trinitrate, GTN, Angina pectoris, Heart failure, Vasodilation, Peripheral vascular resistance, Sublingual, Transdermal, Intravenous, Headache, Hypotension, Methemoglobinemia, PubCompare.ai, SOMATOM Force, Brilliance iCT, SOMATOM Definition Flash, Iomeron 400, Somatom Definition, Aquilion ONE, Brilliance 64, Atlantis SR Pro, Ultravist 370