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Oleylamine

Oleylamine is a long-chain unsaturated amine compound with the chemical formula CH₃(CH₂)₇CH=CH(CH₂)₈NH₂.
It is commonly used as a surfactant, dispersant, and emulsifier in various applications such as nanotechnology, pharmaceuticals, and cosmetics.
Oleylamine plays a crucial role in the synthesis and stabilization of nanoparticles, and it has been explored for its potential in drug delivery systems.
Researchers can optimize their oleylamine-related studies by utilizing PubCompare.ai, an AI-driven platform that helps identify the best protocols from literature, preprints, and patents, enhanceing reproducibility and accuracy.
This platform allows researchers to compare key details and find the optimal solution for their experiments.

Most cited protocols related to «Oleylamine»

The GS-nitroxide JP4-039 has been described in detail previously (17 (link)-21 (link)). JP4-039 (21 (link)) was formulated at final drug concentrations of 8 mg/ml in cationic mutilamellar liposomes termed F-15. F-15 is a unique form of multilamellar liposome (N,N-dioleylamine amido-L-glutamate), which was utilized as a solvent for JP4-039 in order to facilitate adherence of the drug to the esophageal mucosa. The drug is entrapped between lipid bilayers and allows slow release over time from the liposome particles. F-15 was cationically charged to facilitate surface coating and retention for esophageal mucosa. Its composition was: soy PC: Tween-80: N,N-dioleylamine amido-L-glutamate (4:1:1w/w) with a final drug concentration of 8 mg/ml in PBS. It has low toxicity to cultured mammalian cells (>0.5 mg/ml).
Soy phosphatidyl choline, Lissamine rhodamine-phycoerythrin were obtained from Avanti Polar Lipids (Alabaster, AL, USA); Tween-80, tert-boc-L-glutamic acid, oleylamine, dicyclohexylcarbodiimide, N-hydroxysuccinimide, trifluoroacidic acid were obtained from Sigma-Aldrich (St. Louis, MO, USA). Dulbecco's phospate-buffered saline (d-PBS) was obtained from Lonza (Walkersville, MD, USA). A cationic lipid, L-glutamic acid-1,5,-dioleyl amide [NH2-L-Glu(NHC18H36)2] was synthesized using a modified route as previously described (37 (link)), by coupling tert-boc-L-glutamic acid and oleylamine with dicyclohexylcarbodiimide and N-hydroxysuccinimide as the coupling agents, followed by use of trifluoroacidic acid as the deprotecting agent.
The lipid mixture (6 mg) and drug to be encapsulated (1 mg) were dissolved in 100 μl tert-butanol, frozen on dry ice, and lyophilized overnight into a cake. The next day, a 62.5 μl d-PBS was added to the lipid cake which was allowed to hydrate for 24 h at room temperature. Cationic liposomes were prepared from the hydrated lipid suspension by manual homogenization using a pair of custom-made tight-fit tube and pestle until a homogeneous consistency were reached. Finally, the liposome suspension was removed from the tube and another 62.5 μl d-PBS was used to rinse the tube and pestle and the wash solution was combined with the liposome suspension. Thus, 1 mg JP4-039 was formulated in 225 μl volumes. The final particle sizes were measured by a laser dynamic scattering method (NP-4 Particle Sizer, Beckman Coutler, Inc., Brea, CA, USA) and found to be in the range of 200-300 nm with a mean of ~255 nm in diameter. Each mouse received an intraesophageal injection of 110 μls of F15 formulation containing 400 μg JP4-039. To determine whether Tween-80 was required for effective uptake, an identical formulation (F14) without Tween-80 was tested.
Publication 2010
Acids Alabaster Amides Cations Cultured Cells Dicyclohexylcarbodiimide Dry Ice Esophageal Mucosa Freezing Glutamate Glutamic Acid JP4-039 Lecithin Lipid Bilayers Lipids Liposomes Mammals Mice, House N-hydroxysuccinimide nitroxyl oleylamine Pharmaceutical Preparations Phycoerythrin Retention (Psychology) Rhodamine Saline Solution Solvents tert-Butyl Alcohol TERT protein, human Tween 80
The oleic acid (OA)/oleylamine (OLA)-stabilized CdSe/CdS-core/shell-QDs were synthesized according to a modified synthesis described by Carbone et al., Nightingale et al. and Chen et al.65 (link)–67 (link) which is described in detail in the Supplementary Information (SI).
Publication 2022
Anabolism Oleic Acid oleylamine
Binary CdSe and CdS and ternary CdSeS alloyed cores were synthesized from a non-injection heat-up synthesis using a cadmium carboxylate (cadmium behenate or cadmium myristate), SeO2, and elemental S as precursors and 1-octadecene (ODE) as solvent. In a typical synthesis, CdSexS1−x (0 ≤ x ≤ 1) QDs were synthesized by mixing Cd behenate (0.2 mmol), SeO2 (0.2x mmol), and S (0.2(1−x) mmol) in ODE (4 mL) at room temperature and heating to ∼230°C at a rate of ∼20°C/min. The temperature was maintained at 230°C for ∼15 min and the reaction was quenched by decreasing the temperature to ∼100°C and diluting with chloroform (10 mL) containing oleylamine (OLA; 0.6 mL) and oleic acid (1 mL). Finally, a mixture of acetone and methanol was added to precipitate the pure cores. Alloyed HgCdSe(S) cores were prepared via mercury cation exchange on CdSe(S) cores. Typically, CdSe cores dispersed in oleylamine were heated to 50–150°C and mixed with mercury octanethiolate (Cd:Hg = 1:2) to induce cation exchange. After a desired amount of redshift was observed in the absorption spectrum, the reaction was quenched by precipitating the particles with a mixture of acetone and methanol. Details on the chemicals and synthetic parameters for cores with different sizes and compositions are provided in Supplementary Notes 1 and 2
Publication 2015
1-octadecene Acetone Anabolism Cadmium Chloroform Methanol Myristate Oleic Acid oleylamine Solvents
Synthesis of Ag3PO4 nanocrystals: Ag3PO4 nanocrystals were synthesized with reported methods with minor adjustments [6] . In brief, 8.5 g of AgNO3 and 32 mL of oleylamine were dispersed in 150 mL of toluene and stirred for about 2 h at room temperature. After AgNO3 was fully dissolved, an ethanol solution containing 50 mL of ethanol, 2 mL of H2O, 2.84 mL of H3PO4 was added into the above solution. The solution tuned into yellow colloid quickly. After reaction for 30 mins at room temperature, Ag3PO4 nanocrystals were precipitated by adding ethanol, and washed several times with toluene and ethanol. The dark-yellow precipitate was dried in an oven.
Characterization of Ag3PO4 nanocrystals: The phase structure of the as-synthesized products were characterized using X-ray diffraction (XRD, Bruker D8 ADVANCE) with Cu-Kα radiation (λ = 1.5406 Å) at a scanning rate of 6° min−1. The morphology and size of the products were examined by a transmission electron microscope (TEM, JEOL JEM-2100) with an accelerating voltage of 200 kV. The Ag3PO4 product dispersed in ethanol was dropped onto a holey copper grid covered with an amorphous carbon film for the TEM examination.
Surface modification for Ag3PO4 nanocrystals: Before property investigation, the obtained Ag3PO4 nanocrystals were firstly treated through usual ligand exchange route [54] (link) to transfer it to being hydrophilic state. Briefly, about 50 mg of Ag3PO4 nanocrystals were dispersed into the mixture of hexane (35 mL), distilled water (15 mL), and ethanol (30 mL) through magnetic stirring. Then, 6-amino caproic acid (0.13 g) and equivalent molar NH3·H2O in 5 mL of distilled water was added into the above system. After that, the mixture was heated to 70°C and kept at that temperature for 4 h. The nanocrystals were then collected by centrifugation and washed with water. Through this process, the hydrophobic Ag3PO4 nanocrystals were transformed into hydrophilic state, which can be dispersed in water.
Peroxidase-like catalytic activity of Ag3PO4 nanocrystals: The peroxidase-like activity of freshly treated Ag3PO4 nanocrystals was determined by measuring the formation of a blue charge-transfer complex of diamine from TMB at 652 nm (ε = 39000 M−1 cm−1). The TMB oxidation activity measurement, unless otherwise specified, was conducted in sodium acetate buffer (pH 4.0) in the presence of Ag3PO4 nanocrystals (2 mg mL−1) with 0.3 mM of TMB and 3.6 mM of H2O2. The reaction proceeded at 25°C with time of 30 min.
pH Measurements: The activity of the Ag3PO4 nanocrystals at different pH values was performed using the same conditions as above, except different buffer compositions (with different concentration ratios of HAc to NaAc) for different pH values were employed. The reaction was carried out with 2 mg mL−1 of Ag3PO4 nanocrystals to which TMB (0.3 mM) and H2O2 (3.6 mM) were added. The pH of the different buffers was adjusted by using a pH meter.
Determination of kinetic parameters: The steady-state kinetics were performed by varying one of the concentrations of Ag3PO4 nanocrystals (0–4 mg mL−1), H2O2 (0.35–7 mM), or TMB (0–0.45 mM) at a time. The reaction was carried out in acetate buffer (pH 4.0) for 30 min and monitored by measuring the absorbency at 652 nm. The kinetic curves were adjusted according to the Michaelis-Menten model.
Publication 2014
6-Aminocaproic Acid Acetate Buffers Carbon Centrifugation Colloids Copper enzyme activity Ethanol Hexanes Kinetics Ligands Molar oleylamine Peroxidase Peroxide, Hydrogen Radiation Sodium Acetate Toluene Transmission Electron Microscopy Trypan Blue X-Ray Diffraction
For CSS QD synthesis InAs QDs were synthesized using (TMGe)3As or (TMSi)3As as a precursor and purified as described above. The diameter and the concentration of the synthesized particles in solution was determined by using a sizing curve46 (link). Based on QD size a rough estimate of shell precursor material that is necessary to grow a certain amount of shell monolayers was calculated5 (link). However, as InAs QDs do not exhibit a perfectly spherical shape the actual amount of deposited shell material per shell monolayer was found to slightly vary from the calculated values. The shell growth process was monitored by taking frequent aliquots throughout the growth process to determine absorption and fluorescence spectra, as well as QY values such that the final emission peak could be tuned to the desired wavelength. In a typical reaction, purified InAs QDs (96 nmoles, diameter of 4.7 nm, PL emission at 1,039 nm) in hexanes were transferred to a mixture of octadecene (3 ml) and oleylamine (3 ml) in a four neck flask. The mixture of octadecene and oleylamine was previously degassed at 115 °C for at least 1 h. The solution was switched to vacuum to remove the hexanes for 30 min at room temperature and another 10 min at 110 °C. Subsequently, the solution was heated to 280 °C for the shell growth. As soon as the mixture reached 240 °C, shell precursor injection was started using 0.05 M shell precursor solutions in octadecene. Cd(Ol)2 (111 μmoles) and TOPSe (111 μmoles) were added over the course of 67 min (injection speed 2 ml h−1). InAsCdSe CS QDs were purified using the above described procedure (however using acetone and methanol as non-solvents) and stored in hexanes. In contrast to bare InAs cores, the InAs core-shell QDs were not transferred to a glovebox but stored in air. The size was measured to be 5.1 nm (TEM) and the QDs exhibited a PL peak at 1,296 nm. The resulting InAsCdSe (roughly 86 nmoles, 10% loss through aliquots and purification) were redispersed in octadecene (3 ml) and oleylamine (3 ml), and degassed at room temperature for 30 min and at 100 °C for 10 min. To that solution 3 ml of a 0.05 M Cd(Ol)2 and 3 ml of a 0.045 M sulfur solution in octadecene were added (150 μmoles Cd and 135 μmoles S) at 240 °C within 1 h. The final QD diameter was determined to be 6.9 nm (TEM) with a PL emission at 1,307 nm.
Publication 2016
Acetone Anabolism Fluorescence Hexanes indium arsenide Methanol Neck oleylamine Solvents Sulfur Vacuum

Most recents protocols related to «Oleylamine»

Molybdenum(V) chloride (95%), cobalt (ii)
chloride (97%), bis(trimethylsilyl)sulfide (a.k.a.,
hexamethyldisilathiane, synthesis grade), oleylamine (70%, technical
grade), oleic acid (90%, technical grade), 1-ODE (90%, technical grade),
cyclohexane (≥99%, ACS reagent grade), hexane (95%, anhydrous),
methanol (99.8% anhydrous), thiophene (≥99%), and n-decane (≥99%, synthesis grade) were purchased from Sigma-Aldrich.
Acetone (99.8%, extra dry) and 1,2,3,4-tetrahydronaphthalene (a.k.a.
tetralin, TCI America, ≥ 97%) were purchased from VWR. All
chemicals were used without further purification with the exception
of oleylamine and 1-ODE, which were each separately degassed for 1
h by cycling between nitrogen flow and vacuum on a Schlenk line at
80 °C prior to use.
Publication 2024
Gold (Au, Sigma-Aldrich, St. Louis, MI, USA, 99.99+%)-coated silicon (Si) substrates were prepared by physical vapor deposition on a Kurt J. Lesker PVD75 system (Lesker Company, Jefferson Hills, PA, USA). To enhance the interaction between Au and Si, a 10 nm adhesive layer of titanium (Ti, Sigma-Aldrich, 99.99%) was first deposited on Si, with a deposition rate of 0.5 Å/s. Then, a 100 nm Au layer was deposited onto the Ti-Si substrate with a deposition rate of 1.0 Å/s. The obtained Au substrate was analyzed by atomic force microscopy (AFM) on a Park NX20 atomic force microscopy.
Surfactant-encapsulated Pt nanoparticles were synthesized by a chemical reduction method [39 (link)]. In a typical synthesis, 2.5 mg chloroplatinic acid hexahydrate (H2PtCl6·6H2O, Sigma-Aldrich, ACS reagent) and 20.0 mg hexadecyltrimethylammonium bromide (CTAB, Sigma-Aldrich, BioXtra, >99%) were mixed in 4.5 mL deionized (DI) water. The solution was heated to 50 °C under constant stirring (400 rpm) for 2 h. Then, 3.0 mg sodium borohydride (NaBH4, Sigma-Aldrich, ReagentPlus, 99%) was dissolved in 0.5 mL ice-cooled DI water and added dropwise into the solution. The resulting mixture was stirred for another 12 h at 50 °C. The Pt nanoparticles were purified by discarding the precipitate following centrifugation at 3000 rpm for 30 min. The procedure was repeated four times.
To obtain oleylamine-encapsulated Pt nanoparticles, CTAB encapsulated Pt nanoparticles were collected by centrifugation at 13,000 rpm for 30 min. The resulting precipitate was washed with DI water twice and redispersed in oleylamine (Sigma-Aldrich, >98% primary amine)-water solution (0.8 mL oleylamine in 1 mL DI water). The suspension in a closed container was heated to 50 °C and stirred for 12 h. The obtained oleyamine encapsulated Pt nanoparticles were washed three times with methanol (anhydrous, Sigma-Aldrich, 99.8%) and then redispersed in 0.5 mL toluene (anhydrous, Sigma-Aldrich, 99.8%).
The solution was slowly dropped onto a water subphase on a Langmuir-Blodget trough to produce a monolayer of oleylamine-encapsulated Pt nanoparticles. After evaporation of the toluene for 1 h, the film was compressed until a surface tension of 15 mN·m−1 was achieved. The resulting film was then aged for 30 min before being transferred to an Au-coated Si substrate via a pull-out method.
Publication 2024
Nickel(II) acetylacetonate (Ni(acac)2, 90%), Dioctyl ether (99%), trioctylphosphine (90%), oleylamine (70%) and low-density polyethylene were purchased from Sigma-Aldrich (St. Louis, MO, USA). Zeolite HY (zeolite Y modified with hydrogen) was purchased from Thermo Scientific (Waltham, MA, USA).
Publication 2024
The measurements were performed with a Cary 630 FTIR from Agilent Technologies. Oleylamine and oleic acid were mixed with hydrazine in a glass vial and a drop of this mixture was casted onto the device sample holder. In case of the ligands
Publication 2024
CdSe/CdS-core/shell-NPLs with a shell thickness of 4.5 ML, surface stabilized with oleic acid and oleylamine, were synthesized according to a procedure adapted from Tessier et al. Abécassis et al. Miethe et al. and Rossinelli et al.48 (link)–51 (link) The NPL synthesis is detailed in the SI.
Publication 2024

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Oleylamine is a chemical compound used as a surfactant, emulsifier, and lubricant in various industrial applications. It is a long-chain aliphatic amine with a hydrocarbon backbone and an amino group at one end. Oleylamine is commonly used in the formulation of lubricants, coatings, and personal care products.
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Oleic acid is a long-chain monounsaturated fatty acid commonly used in various laboratory applications. It is a colorless to light-yellow liquid with a characteristic odor. Oleic acid is widely utilized as a component in various laboratory reagents and formulations, often serving as a surfactant or emulsifier.
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1-octadecene is a linear alkene with the molecular formula C18H36. It is a colorless, oily liquid that is commonly used as a chemical intermediate in various industrial and laboratory applications.
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Toluene is a colorless, flammable liquid with a distinctive aromatic odor. It is a common organic solvent used in various industrial and laboratory applications. Toluene has a chemical formula of C6H5CH3 and is derived from the distillation of petroleum.
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Hexane is a colorless, flammable liquid used in various laboratory applications. It is a saturated hydrocarbon with the chemical formula C6H14. Hexane is commonly used as a solvent, extraction agent, and cleaning agent in scientific and industrial settings.
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Ethanol is a clear, colorless liquid chemical compound commonly used in laboratory settings. It is a key component in various scientific applications, serving as a solvent, disinfectant, and fuel source. Ethanol has a molecular formula of C2H6O and a range of industrial and research uses.
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Oleylamine is a long-chain, unsaturated primary amine compound. It is a colorless to pale-yellow liquid with a characteristic amine odor. Oleylamine is commonly used as a surfactant and emulsifier in various applications, including the synthesis of nanoparticles and the formulation of lubricants and personal care products.
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Octadecene is a long-chain hydrocarbon compound with the chemical formula CH3(CH2)16CH=CH2. It is a colorless, oily liquid at room temperature. Octadecene is commonly used as a chemical intermediate in various industrial applications.
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Cesium carbonate is an inorganic compound with the chemical formula Cs2CO3. It is a white, crystalline solid that is soluble in water and commonly used in various laboratory applications.
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1,2-hexadecanediol is a chemical compound used in various industrial and laboratory applications. It is a long-chain diol with the chemical formula C16H34O2. This product is commonly used as a reagent, intermediate, or additive in various chemical processes and formulations.

More about "Oleylamine"

Oleylamine is a long-chain unsaturated amine compound with the chemical formula CH₃(CH₂)₇CH=CH(CH₂)₈NH₂.
It is also known as octadecenylamine, n-octadecylamine, or cis-9-octadecenylamine.
This versatile molecule is commonly employed as a surfactant, dispersant, and emulsifier in a variety of applications, including nanotechnology, pharmaceuticals, and cosmetics.
Oleylamine plays a crucial role in the synthesis and stabilization of nanoparticles, making it an important component in nanomaterial research and development.
Its ability to interact with and stabilize nanoparticles has been leveraged in drug delivery systems, where it can enhance the bioavailability and targeting of therapeutic agents.
Researchers can optimize their oleylamine-related studies by utilizing PubCompare.ai, an AI-driven platform that helps identify the best protocols from literature, preprints, and patents.
This enhances the reproducibility and accuracy of their experiments.
PubCompare.ai allows researchers to compare key details, such as reaction conditions, reagents (e.g., Oleic acid, 1-octadecene, Toluene, Hexane, Ethanol, Octadecene, Cesium carbonate, 1,2-hexadecanediol), and characterization methods, to find the optimal solution for their specific needs.
By taking advantage of this powerful tool, researchers can streamline their oleylamine-related studies, leading to more efficient and effective research outcomes.
Whether you're working on nanoparticle synthesis, drug delivery systems, or other applications involving oleylamine, PubCompare.ai can help you navigate the available literature and protocols to achieve your research goals.