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Red DND-99

Red DND-99 is a compound of interest in biomedical research.
It is a potent inhibitor of a key enzyme involved in cellular processes.
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The platform allows users to quickly locate the best protocols from literature, pre-prints, and patents using intelligent comparisons.
Leveraging AI, researchers can identify the optimal products and streamline their Red DND-99 research process.
Experienve the power of PubCompare.ai to accelerate discoveries related to this important compound.

Most cited protocols related to «Red DND-99»

1
Live Imaging of Axonal Organelles
Cited 8 times
For tracking of lysosomes and mitochondria, cells were double-stained live with 50 nM Lysotracker Red DND-99 (Molecular Probes Cat. No. L-7528) and 50 nM Mitotracker Deep Red FM (Molecular Probes Cat. No. M22426). For measuring mitochondrial membrane potential (and tracking as well), cells were stained with 200 nM Mitotracker JC-1 (Molecular Probes Cat. No. M34152). Trackers were added directly to culture supernatants and incubated for 1 h at 37 °C. Imaging was then performed without further washing of cells. Live imaging of compartmentalized axons in Xona Microfluidic Chambers (MFC) was performed with a Leica HC PL APO 100 × 1.46 oil immersion objective on an inversed fluorescent Leica DMI6000 microscope enclosed in an incubator chamber (37 °C, 5% CO2, humid air) and fitted with a 12-bit Andor iXON 897 EMCCD camera (512×512, 16 µm pixels, 229.55 nm/pixel at 100Χ magnification). For more details, refer to https://www.biodip.de/wiki/Bioz06_-_Leica_AFLX6000_TIRF. Excitation was performed with a TIRF Laser module in epifluorescence (widefield) mode with lines at 488, 561 and 633 nm. Fast dual color movies were recorded at 3.3 frames per second (fps) per channel over 2 min (400 frames in total per channel) with 115 ms exposure time as follows: Lysotracker Red (excitation: 561 nm, emission filter TRITC 605/65 nm) and Mitotracker Deep Red (excitation: 633 nm, emission filter Cy5 720/60 nm) or for Mitotracker JC-1 with excitation at 488 nm and fast switching between emission filter FITC 527/30 nm (green channel for compromised membrane potential) and TRITC 605/65 nm (red channel for intact membrane potential). Movie acquisition was performed at strictly standardized readout positions within the micro channels of the micro groove barrier that separated the proximal seeding site from the distal axonal exit as illustrated in Fig. 2a. Specifically, the readout windows were located either just adjacent to the channel exit (distal readout) or the channel entry (proximal readout).
Naumann M., Pal A., Goswami A., Lojewski X., Japtok J., Vehlow A., Naujock M., Günther R., Jin M., Stanslowsky N., Reinhardt P., Sterneckert J., Frickenhaus M., Pan-Montojo F., Storkebaum E., Poser I., Freischmidt A., Weishaupt J.H., Holzmann K., Troost D., Ludolph A.C., Boeckers T.M., Liebau S., Petri S., Cordes N., Hyman A.A., Wegner F., Grill S.W., Weis J., Storch A, & Hermann A. (2018). Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. Nature Communications, 9, 335.
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Publication 2018
Apolipoprotein A-I Axon Cells Fluorescein-5-isothiocyanate Ion Channel Lysosomes LysoTracker Membrane Potential, Mitochondrial Membrane Potentials Microscopy Mitochondria Molecular Probes Reading Frames Red DND-99 Submersion tetramethylrhodamine isothiocyanate
2
Molecular Analysis of Etv5 Mutants
Cited 7 times

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Publication 2009
CD3E protein, human Cell Death DNA, Complementary Embryo Hindlimb In Situ Hybridization Lateral Plate Mesoderm Limb Buds LysoTracker Red DND-99 Skeleton Somites Student
3
Meibomian Gland Epithelial Cell Lipid Analysis
Cited 6 times
Immortalized human meibomian gland epithelial cells (HMGECs) were cultured in media that promote either proliferation (serum-free) or differentiation (serum-containing), according to published techniques.6 (link) Cells were treated with ethanol vehicle, azithromycin (10 μg/ml; Santa Cruz Biotechnology, Dallas, TX), doxycycline (0.1 to 10 μg/ml; Sigma-Aldrich, St. Louis, MO), minocycline (0.1 to 10 μg/ml; Sigma-Aldrich) or tetracycline (0.1 to 10 μg/ml; Sigma-Aldrich) for 5 days. These doses were selected based upon our preliminary experiments with HMGECs and on their established safety in human corneal cells.10 (link),11 (link)Cell numbers were counted with a hemocytometer. Cellular neutral lipid and lysosome accumulation were evaluated with LipidTOX green neutral lipid stain (Life Technologies, Grand Island, NY) and LysoTracker Red DND-99 (Life Technologies). All experiments were repeated at least three times. Each experiment was performed in duplicate under the same conditions. Data from one representative experiment were used for quantitation. Eight random pictures were taken of each group on the same day with the same exposure time, and the whole cell area in each picture was selected for the measurement of fluorescent intensities. The data show the mean fluorescence intensity of all the cells in each picture, and cell number was similar in all groups. Total cellular lipid composition was analyzed by high performance thin-layer chromatography (HPTLC).12 Each sample contained the same amount of cellular extract, and cell lysates were analyzed by immunoblot. Membranes were incubated with antibodies specific for SREBP-1 (Santa Cruz, H-160, 1:500), cyclin B1 (Cell Signaling Technology, Danvers, MA; 1:500) or β-actin (Cell Signaling Technology, 1:10,000), followed by HRP-conjugated secondary antibodies (1:5,000, Sigma-Aldrich). The fluorescence intensities of LipidTOX and LysoTracker, as well as immunoblot band intensities, were quantified by using ImageJ.
For statistical evaluation, ANOVA and Newman-Keuls multiple comparisons tests were performed with Prism 5 software (GraphPad Software, Inc., La Jolla, CA).
Liu Y., Kam W.R., Ding J, & Sullivan D.A. (2015). Can tetracycline antibiotics duplicate the ability of azithromycin to stimulate human meibomian gland epithelial cell differentiation?. Cornea, 34(3), 342-346.
Publication 2014
Actins Antibodies Azithromycin Cell Extracts Cells Cornea Culture Media Cyclin B1 Doxycycline Epithelial Cells Ethanol Fluorescence Homo sapiens Immunoblotting Lipids Lysosomes LysoTracker Meibomian Glands Minocycline neuro-oncological ventral antigen 2, human prisma Red DND-99 Safety Serum SREBF1 protein, human Stains Tetracycline Thin Layer Chromatography Tissue, Membrane
4
Synthesis and Characterization of PEGylated Gemcitabine Prodrugs
Cited 5 times

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Publication 2012
Aldehydes Amides Bromides Carbodiimides Cell Culture Techniques Cell Lines Cells Culture Media Diagnosis Fetal Bovine Serum Gemcitabine Gemcitabine Hydrochloride gemcitabine triphosphate High-Performance Liquid Chromatographies HOE 33342 Hydrazones Lung Cancer LysoTracker Malignant Neoplasms Methanol Molecular Probes Mus Penicillins perchlorate polyethylene glycol 2000 Pyrenes Red DND-99 Solvents stearic acid Streptomycin Sulfate, Sodium Dodecyl Synthetic Drugs tert-butyl carbazate tetrabutylammonium chloride tetrahydrofuran triphosphate
5
Live Cell Imaging of Cellular Responses
Cited 4 times
For the evaluation of cellular responses to both incubation with DON and uniaxial stretching, live cell imaging experiments were performed. Cellular structures/organelles were stained with specific dyes: cell membrane was stained with CellMask™ Deep Red Plasma membrane Stain (1:1000 dilution, white), lysosomes with LysoTracker® Red DND-99 (1:1000 dilution, red, indicated as LysoTracker), mitochondria with MitoTracker® Green FM (1:1000 dilution, green, indicated as MitoTracker), tubulin with TubulinTracker™ Green (1:2000 dilution, green, indicated as TubulinTracker), and cell nuclei with Hoechst 33258 (1:1000 dilution, blue). Staining solutions were diluted in Live Cell Imaging Solution (all from Molecular Probes, Life Technologies, Thermo Fisher Scientific, Waltham, USA). At the end of the staining, cells were rinsed and maintained in Live Cell Imaging Solution for the microscopy analysis. Time series and confocal images were acquired with Confocal LSM Zeiss 710 equipped with ELYRA PS. 1 using a Plan Apochromat 63X/1.4 oil objective (Figs 1–3), whereas membranes were imaged with a Plan Neofluar 10X/0.3 (zoom 4; Figs 4–6). Moreover, membranes were also analyzed with the Cytation3 Imaging Multi-Mode Reader (BioTek, Winooski, VT, USA) for image acquisition and evaluation of the fluorescent signal (objects-mean per optical field; Fig. 7).
Del Favero G., Woelflingseder L., Janker L., Neuditschko B., Seriani S., Gallina P., Sbaizero O., Gerner C, & Marko D. (2018). Deoxynivalenol induces structural alterations in epidermoid carcinoma cells A431 and impairs the response to biomechanical stimulation. Scientific Reports, 8, 11351.
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Publication 2018
Cell Nucleus Cells Cellular Structures Dyes Hoechst 33258 Lysosomes LysoTracker Microscopy Mitochondria mitotracker green FM Molecular Probes Organelles Plasma Membrane Red DND-99 Stains Technique, Dilution Tissue, Membrane Tubulin

Most recents protocols related to «Red DND-99»

1
Fluorescent lipid trafficking in PTECs
A fluorescent fatty acid pulse-chase assay was performed as described previously, with slight modification (71 (link)). PTECs were incubated with low-glucose DMEM and 5% FBS containing 2 μM β-BODIPY FL HPC (Thermo Fisher Scientific, D3792) for 16 hours, then washed 3 times with DMEM with 5% FBS, incubated for 1 hour to allow the fluorescent lipids to incorporate into cellular membranes, and chased for 6 hours under BSA or PA treatment. PTECs were then stained with 50 nM LysoTracker Red DND-99 (Thermo Fisher Scientific, L7528) at 37°C for 30 minutes before imaging. FL-HPC–positive and LysoTracker-negative dots outside the cells were counted as released phospholipids. In addition, to assess the clearance of lysosomal phospholipid accumulation, we observed PA-treated PTECs for 12 or 24 hours after PA washout. The number of dots indicating staining for both phospholipids and lysosomes was determined using the ImageJ (NIH) “analyze particles” function.
Nakamura J., Yamamoto T., Takabatake Y., Namba-Hamano T., Minami S., Takahashi A., Matsuda J., Sakai S., Yonishi H., Maeda S., Matsui S., Matsui I., Hamano T., Takahashi M., Goto M., Izumi Y., Bamba T., Sasai M., Yamamoto M., Matsusaka T., Niimura F., Yanagita M., Nakamura S., Yoshimori T., Ballabio A, & Isaka Y. (2023). TFEB-mediated lysosomal exocytosis alleviates high-fat diet–induced lipotoxicity in the kidney. JCI Insight, 8(4), e162498.
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Publication 2023
Biological Assay BODIPY Cells Fatty Acids Glucose Lipids Lysosomes LysoTracker Phospholipids Plasma Membrane Pulse Rate Red DND-99
2
Synthesis and Characterization of Zinc-based Nanoparticles
2-methylimidazole (98%) was purchased from Energy Chemical Co., Ltd (Shanghai, China). ZnCl2 was purchased from Macklin Biochemical Co., Ltd (Shanghai, China). Cetyltrimethylammonium bromide (CTAB) was purchased from Aladdin Biochemical Technology Co., Ltd (Shanghai, China). Sodium ethylene diamine tetraacetic acid (EDTA-Na2) was purchased from Sinopharm Chemical Reagent Co., Ltd (Shanghai, China). Nucleic acid dye SYBR GREEN II, 4% tissue fix solution, and DAPI dye were purchased from Beijing Solarbio Science & Technology Co., Ltd. (Beijing, China). The Formvar support film was purchased from Zhongjingkeyi Film Technology Co., Ltd. (Beijing, China). The cell Counting Kit-8 (CCK-8) kit was purchased from LABLEAD. Inc (Beijing, China). 3′,6′-Dihydroxy-5-isothiocyanato-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (FITC), PRIM-1640, 0.25% trypsin–EDTA (1×), PBS (1×), penicillin–streptomycin solution and LysoTracker™ Red DND-99 lysosomal probe were purchased from Thermo Fisher Scientific (Massachusetts, USA). Dendritic cells 2.4 were saved by our laboratory. All other reagents were all analytical grade and used without further treatment. Unless otherwise specified, deionized water for injection was used for solution preparation.
Wang L., Lin X., Sheng Y., Zhu H., Li Z., Su Z., Yu R, & Zhang S. (2023). Synthesis of a crystalline zeolitic imidazole framework-8 nano-coating on single environment-sensitive viral particles for enhanced immune responses. Nanoscale Advances, 5(5), 1433-1449.
Publication 2023
2-methylimidazole Cetrimonium Bromide DAPI Dendritic Cells Edetic Acid Fluorescein-5-isothiocyanate Formvar Lysosomes LysoTracker Nucleic Acids Penicillins Red DND-99 Sodium Streptomycin SYBR Green II Tissues Trypsin
3
Intracellular Uptake of Fluorescent ASO
The amount of fluorescently labeled 6-FAM ASO taken up by cells was measured by flow cytometry and confocal microscopy. ST14A cells were plated in 24-well tissue culture plates at 1.5 × 105 cells/well 24 h prior to transfection. After 24 h, cells were washed twice with D-PBS and CDs:ASO nanocomplexes were added to cells in serum-reduced medium (2% FBS) at a final concentration of 100 nM 6-FAM labeled ASO. After 6 h of incubation, cells were washed with D-PBS, trypsinized, and collected into a complete DMEM medium. Samples were centrifuged for 5 min at 1500 rpm at 4 °C and resuspended in 400 μL of D-PBS. All data were acquired on a BD FACSCelesta™ flow cytometer (FACSCalibur, BD Biosciences, San Jose, CA, USA) and analyzed using FlowJo™ Software (version 10).
For confocal imaging, ST14A cells (1.25 × 105 cells per well) and GM04723 (1.0 × 105 cells) were seeded on round coverslips, at per coverslip in a 24-well plate and 500 uL medium. After 24 h, the medium was replaced with 400 uL of serum-reduced medium (2% FBS) plus 100 uL of 6-FAM labeled ASO (at a final concentration of 100 nM ASO). For staining of lysosomes, 50 nM LysoTracker Red DND-99 (ThermoFisher, Bremen, Germany) was added into the medium 1 h prior to fixation with 4% PFA (6 h of incubation in total). Coverslips were mounted in Mowiol, and confocal images were acquired on a Zeiss LSM510 META confocal microscope (Carl Zeiss, Jena, Germany) using a 63× objective.
Mendonça M.C., Sun Y., Cronin M.F., Lindsay A.J., Cryan J.F, & O’Driscoll C.M. (2023). Cyclodextrin-Based Nanoparticles for Delivery of Antisense Oligonucleotides Targeting Huntingtin. Pharmaceutics, 15(2), 520.
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Publication 2023
Cell Culture Techniques Cells Flow Cytometry Lysosomes LysoTracker Microscopy, Confocal Red DND-99 Serum Tissues Transfection
4
Hydroxyethyl Cellulose-based Nanoparticle Synthesis
Hydroxyethyl cellulose (HEC, viscosity: ~145 mPa∙s in 1% H2O, average molecular weight: ~250,000 Da, provided by the manufacturer), branched polyethylenimine (PEI25k, 25 kDa), agarose, gel loading solution, ethidium bromide, dimethyl sulfoxide (DMSO), MicroBCA™ protein assay kit, 4′,6-diamidino-2-phenylindole (DAPI), and triethylamine (TEA) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Branched polyethylenimine (PEI, 2 kDa) was purchased from Polysciences (Warrington, PA, USA). Sodium metaperiodate (NaIO4) was purchased from Alfa-aesar (Haverhill, MA, USA). Sodium tetrahydroborate (NaBH4) and HPLC water were purchased from Duksan (Ansan, Korea). Formic acid was purchased from Merck (Darmstadt, Germany). Triazolyl blue tetrazolium bromide (MTT) was purchased from Gold Biotechnology (St. Louis, MO, USA). pDNA (pCN-Luci) was amplified by using Dyne DH5α Chemically Competent E.coli ver.2 (DYNEBIO, Sungnam, Korea) and purified by using NucleoBond Xtra Maxi (Macherey-Nagle, Duren, Germany). Dulbecco’s Modified Eagle Medium (DMEM) and Dulbecco’s phosphate buffered saline (DPBS) were purchased from Cytiva (Marlborough, MA, USA). DMEM + GlutaMAX (GMX), fetal bovine serum (FBS), penicillin–streptomycin (P–S), and trypsin-EDTA were purchased from Gibco (Waltham, MA, USA). Luciferase assay system and reporter lysis buffer were purchased from Promega (Madison, WI, USA). YOYO-1 iodide and Lysotracker Red DND-99 were purchased from Invitrogen (Waltham, MA, USA). Doxorubicin hydrochloride (Dox∙HCl) was purchased from Cayman Chemical (Ann Arbor, MI, USA). Alexa Fluor 488 Annexin V/Dead cell apoptosis kit was purchased from Life Technologies (Carlsbad, CA, USA). Bcl-2 siRNA (5′-GUGAAGUCAACAUGCCUGC-3′ (sense), 5′-GCAGGCAUGUUGACUUCAC-3′ (anti-sense)) was purchased from Bioneer (Daejeon, Korea).
Park J., Kim S, & Kim T.I. (2023). Polyethylenimine-Conjugated Hydroxyethyl Cellulose for Doxorubicin/Bcl-2 siRNA Co-Delivery Systems. Pharmaceutics, 15(2), 708.
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Publication 2023
1,1'-((4,4,7,7-tetramethyl)-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-oxazole)-2-methylidine)quinolinium, tetraiodide alexa fluor 488 Annexin A5 Apoptosis BCL2 protein, human Biological Assay Bromides Buffers Caimans Cells Eagle Edetic Acid Escherichia coli Ethidium Bromide Fetal Bovine Serum formic acid Gold High-Performance Liquid Chromatographies Hydrochloride, Doxorubicin hydroxyethylcellulose Iodides Luciferases LysoTracker Penicillins Phosphates Polyethyleneimine Promega Proteins Red DND-99 RNA, Small Interfering Saline Solution Sepharose sodium borohydride sodium metaperiodate Streptomycin Sulfoxide, Dimethyl Tetrazolium Salts triethylamine Trypsin Viscosity
5
Intracellular Trafficking of Polyplexes
Intracellular trafficking of the polyplexes was observed by using a confocal laser scanning microscope (CLSM). HeLa cells were seeded on a confocal dish at a density of 3 × 105 cells/dish in 3 mL of medium and incubated for 24 h until the cells achieved 70–80% confluency. After exchange with fresh serum-free medium, the cells were treated with HECP2k/pDNA polyplex solutions (1.5 μg of pDNA/dish, pDNA labeled with YOYO-1 iodide) with optimal weight ratio (50). PEI25k/pDNA polyplex (weight ratio = 1) was used as a control. After 4 h of incubation, the medium was exchanged with fresh medium containing 10% FBS and further incubated for 2 h or 4 h. Then, acidic organelles were stained using Lysotracker Red DND-99 solution (100 nM) and the cells were fixed with 4% paraformaldehyde. Nuclei were labeled with DAPI solution (0.125 μg/mL). After sufficient rinsing of cells, visualization proceeded with a confocal laser scanning microscope (SP8 X STED, Leica, Wetzlar, Germany) and the images were processed with LAS X software.
Park J., Kim S, & Kim T.I. (2023). Polyethylenimine-Conjugated Hydroxyethyl Cellulose for Doxorubicin/Bcl-2 siRNA Co-Delivery Systems. Pharmaceutics, 15(2), 708.
Full text: Click here
Publication 2023
1,1'-((4,4,7,7-tetramethyl)-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-oxazole)-2-methylidine)quinolinium, tetraiodide Acids Cell Nucleus Cells DAPI HeLa Cells Hyperostosis, Diffuse Idiopathic Skeletal Iodides LysoTracker Microscopy, Confocal Organelles paraform Protoplasm Red DND-99 Serum

Top products related to «Red DND-99»

1
Lysotracker red dnd 99 by Thermo Fisher Scientific
Sourced in United States, United Kingdom, Germany, Japan, France, China, Spain
LysoTracker Red DND-99 is a fluorescent dye that selectively stains acidic organelles, such as lysosomes, in live cells. It can be used to visualize and monitor the distribution and activity of lysosomes within the cellular environment.
2
Hoechst 33342 by Thermo Fisher Scientific
Sourced in United States, Germany, United Kingdom, Japan, China, France, Canada, Spain, Belgium, Italy, Australia, Austria, Denmark, Netherlands, Switzerland, Ireland, New Zealand, Portugal, Brazil, Argentina, Singapore, Poland, Ukraine, Macao, Thailand, Finland, Lithuania, Sweden
Hoechst 33342 is a fluorescent dye that binds to DNA. It is commonly used in various applications, such as cell staining and flow cytometry, to identify and analyze cell populations.
3
Mitotracker green fm by Thermo Fisher Scientific
Sourced in United States, Germany, United Kingdom, Japan, Australia, France, Italy
MitoTracker Green FM is a fluorescent dye that specifically labels mitochondria in live cells. It passively diffuses across the plasma membrane and accumulates in active mitochondria. The dye exhibits bright green fluorescence upon binding to mitochondrial lipids.
4
4 6 diamidino 2 phenylindole (dapi) by Thermo Fisher Scientific
Sourced in United States, Germany, United Kingdom, Japan, China, Canada, Italy, Australia, France, Switzerland, Spain, Belgium, Denmark, Panama, Poland, Singapore, Austria, Morocco, Netherlands, Sweden, Argentina, India, Finland, Pakistan, Cameroon, New Zealand
DAPI is a fluorescent dye used in microscopy and flow cytometry to stain cell nuclei. It binds strongly to the minor groove of double-stranded DNA, emitting blue fluorescence when excited by ultraviolet light.
5
Fetal bovine serum (fbs) by Thermo Fisher Scientific
Sourced in United States, China, United Kingdom, Germany, Australia, Japan, Canada, Italy, France, Switzerland, New Zealand, Brazil, Belgium, India, Spain, Israel, Austria, Poland, Ireland, Sweden, Macao, Netherlands, Denmark, Cameroon, Singapore, Portugal, Argentina, Holy See (Vatican City State), Morocco, Uruguay, Mexico, Thailand, Sao Tome and Principe, Hungary, Panama, Hong Kong, Norway, United Arab Emirates, Czechia, Russian Federation, Chile, Moldova, Republic of, Gabon, Palestine, State of, Saudi Arabia, Senegal
Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
6
Mitotracker red cmxros by Thermo Fisher Scientific
Sourced in United States, Germany, United Kingdom, Japan, China, Italy, Canada, Spain, France, Belgium
MitraTracker Red CMXRos is a fluorescent dye that can be used to stain mitochondria in live cells. It is a cell-permeant dye that accumulates in active mitochondria, enabling the visualization and analysis of mitochondrial structure and function.
7
Mitotracker deep red fm by Thermo Fisher Scientific
Sourced in United States, United Kingdom, Germany, Switzerland
MitraTracker Deep Red FM is a fluorescent dye that selectively stains mitochondria in live cells. It is membrane-permeant and accumulates in active mitochondria based on their membrane potential. This product can be used to visualize and analyze mitochondrial morphology and distribution.
8
Hoechst 33342 by Merck Group
Sourced in United States, Germany, Italy, United Kingdom, Japan, China, France, Sao Tome and Principe, Canada, Macao, Belgium, Israel, Spain, Australia, Poland, Switzerland, India, Denmark, Austria, Netherlands
Hoechst 33342 is a fluorescent dye that binds to DNA. It can be used to visualize and quantify nucleic acids in various applications such as flow cytometry, fluorescence microscopy, and nucleic acid staining.
9
Lysotracker green dnd 26 by Thermo Fisher Scientific
Sourced in United States, United Kingdom, Italy, China, Sweden, Germany
LysoTracker Green DND-26 is a fluorescent probe that selectively stains acidic organelles, such as lysosomes, in live cells. It is a membrane-permeant dye that accumulates in acidic compartments due to protonation. The dye exhibits green fluorescence upon uptake, allowing visualization and tracking of lysosomal dynamics.
10
Lysosensor green dnd 189 by Thermo Fisher Scientific
Sourced in United States
LysoSensor Green DND-189 is a fluorescent dye used for detecting and visualizing acidic organelles, such as lysosomes, in live cells. It exhibits a pH-dependent increase in fluorescence upon accumulation in acidic environments.

More about "Red DND-99"

Red DND-99 is a compound of significant interest in the realm of biomedical research.
It is a potent inhibitor of a crucial enzyme involved in essential cellular processes.
The compound's versatility and importance have led researchers to explore its applications further.
Alongside Red DND-99, other related compounds like LysoTracker Red DND-99, Hoechst 33342, MitoTracker Green FM, and DAPI have also garnered attention for their unique properties and potential applications in various fields of study.
These fluorescent dyes are widely used in cellular and molecular biology research, offering valuable insights into the dynamics of subcellular organelles, such as lysosomes and mitochondria.
To optimize the research process and enhance reproducibility, researchers can leverage the AI-powered platform of PubCompare.ai.
This innovative tool allows users to quickly locate the best protocols from literature, preprints, and patents, using intelligent comparisons.
By harnessing the power of artificial intelligence, researchers can identify the optimal products and streamline their Red DND-99 research process, leading to more efficient and effective discoveries.
Furthermore, the platform's capabilities extend beyond Red DND-99, enabling researchers to explore and utilize other related compounds like MitoTracker Red CMXRos, MitoTracker Deep Red FM, LysoTracker Green DND-26, and LysoSensor Green DND-189.
These tools can provide valuable insights and enhance the overall research workflow, ultimately accelerating the advancement of knowledge and the development of new applications.
Experienve the transformative power of PubCompare.ai and unlock the full potential of your Red DND-99 research project.