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Remifentanil

Remifentanil is a short-acting, potent opioid analgesic used for anesthesia induction and maintenance.
It is rapidly metabolized by nonspecific esterases, resulting in a short duration of action and rapid recovery.
Remifentanil is commonly used in surgical procedures to provide pain relief and sedation.
However, its use requires careful monitoring due to the risk of respiratory depression and other adverse effects.
PubCompare.ai's powerful tool can help streamline Remifentanil research by enhancing reproducibility and accuracy, locating relevant protocols, and leveraging AI-driven comparisons to identify the best protocols and products.

Most cited protocols related to «Remifentanil»

1
Functional Neuroimaging of Pain and Analgesia
Cited 16 times
In all four studies, we applied thermal stimuli in randomized sequences of varying intensity (trials) to the left forearm of each participant during fMRI scanning. For imaging, we used a 1.5-T General Electric scanner in studies 1, 3, and 4 and a 3-T Phillips scanner in study 2.
Participants in study 1 underwent 12 trials at each of four intensities, which were calibrated for each person: innocuous warmth (defined with the use of self-report by the participant as level 1 on a 9-point visual-analogue scale [VAS], with a mean [±SD] temperature of 41.0±1.9°C) and three levels of painful heat (participant-defined levels 3, 5, and 7, with mean temperatures of 43.3±2.1°C, 45.4±1.71°C, and 47.1±0.98°C, respectively). Each trial consisted of a warning cue and anticipation period (8 seconds), stimulation (10 seconds), and a pain-recall and rating period (4 seconds), with periods of rest before and after recall.
Participants in study 2 underwent a total of 75 trials across six temperatures (44.3 to 49.3°C in 1°C increments). After each trial, participants judged whether the stimulus was painful. They subsequently judged nonpainful warmth on a 100-point VAS and pain intensity on a 100-point VAS. Ratings were coded from 0 to 99 for nonpain-ful events and from 100 to 200 for painful events.
Participants in study 3 underwent 32 trials, consisting of 8 trials with each of four stimulus types. We delivered noxious heat (46.6±1.7°C, denoted “painful”) and warmth that was near the pain threshold (39.9±2.8°C, denoted “warm”) at temperatures calibrated for each person. Each participant had recently experienced a romantic breakup and continued to feel intensely rejected. During scanning, participants viewed an image of their ex-partner (denoted as “rejecter” trials, which elicit social pain8 (link)) and an image of a close friend (denoted as “friend” trials).
Participants in study 4 received two intravenous infusions of remifentanil, a potent μ-opioid agonist, during fMRI scanning in two series of trials. In the open-infusion series, participants knew they received remifentanil, and in the hidden-infusion series, they were told that no drug was delivered, even though it had been administered. Remifentanil doses (mean dose, 0.043±0.01 μg per kilogram of body weight per minute) were individually calibrated before the session to elicit analgesia without sedation, and we estimated the brain concentration of the drug over time using a pharmacokinetic model.9 (link) We conducted 36 trials — 18 involving pain (mean temperature, 47.1±1.7°C) and 18 involving warmth (mean temperature, 41.2±2.6°C) — during each of the two infusion series. Drug infusion began partway through each series, after 6 trials, and ended after 24 trials. This design resulted in a continuously varying concentration of the drug over time during each infusion series.
Wager T.D., Atlas L.Y., Lindquist M.A., Roy M., Woo C.W, & Kross E. (2013). An fMRI-Based Neurologic Signature of Physical Pain. The New England journal of medicine, 368(15), 1388-1397.
Publication 2013
Body Weight Brain Electricity Feelings fMRI Forearm Friend Intravenous Infusion Management, Pain Mental Recall Neoplasm Metastasis Opioids Pain Pharmaceutical Preparations Remifentanil Sedatives Severity, Pain Visual Analog Pain Scale
2
In Vivo Porcine Anesthesia and Euthanasia Protocol
Cited 11 times
All experiments were performed in vivo. Ethical approval
was obtained from The University of Auckland Animal Ethics Committee and the
International Guiding Principles for Biomedical Research Involving Animals were
followed. Sixteen white cross-breed weaner pigs were employed, of either sex and
of mean weight 36.7 ± 0.5 kg. The pigs were fasted then subjected to
general anesthesia that was induced with Zoletil (Tiletamine HCl 50 mg
mL−1 and Zolazepam HCl 50 mg mL−1),
and maintained with Isoflurane (2.5–5% with an oxygen flow of
400 mL within a closed circuit anesthetic system). A possible alternative
regimen of remifentanil/propofol has been found to be associated with pyloric
spasm in pigs and therefore was not considered.6 (link)A femoral artery was cannulated and vital signs were continuously
monitored including heart rate and blood pressure. Rectal and intra-abdominal
temperatures were also monitored, and these were kept in the normal
physiological range (38.5–39.5 °C) by continuous use of a
heating pad and the additional use of a heat lamp when necessary. A midline or
bilateral subcostal laparotomy was performed depending on the gastric region of
experimental interest, the latter incision being more suitable for
investigations of the proximal stomach. At the conclusion of the experiments,
the animals were euthanized with a bolus injection of 50 mL of magnesium sulfate
while still under anesthesia.
Egbuji J.U., O’Grady G., Du P., Cheng L.K., Lammers W.J., Windsor J.A, & Pullan A.J. (2010). Origin, propagation and regional characteristics of porcine gastric slow wave activity determined by high-resolution mapping. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 22(10), e292-e300.
Publication 2010
Anesthesia Anesthetics Animal Ethics Committees Animals Blood Pressure Femoral Artery Isoflurane Laparotomy Magnesium Oxygen Propofol Rate, Heart Rectum Remifentanil Signs, Vital Stomach Sus scrofa Tiletamine Zolazepam Zoletil
3
Awake Brain Tumor Surgery Protocol
Cited 9 times
The study protocol and informed consent documents were approved by the Ethics Committee of Verona University Hospital. All patients provided their informed consent prior to entering the study. The study population was seven patients (4 males and 3 females; mean age, 54±19.9 years; range, 36–85) undergoing brain tumor surgery for: glioma (n = 4); meningioma (n = 1); and cavernous angioma (n = 2) (Table 1). Since patient guidance is essential and each step of the stimulation procedure is announced, the patients were awake after craniotomy. Anesthesia was induced with bolus doses of propofol 0.8 mg Kg−1h−1, remifentanil 0.01 gamma Kg−1 min−1 totally endovenous and 5 mg midazolam (benzodizepine) as co-adjuvant. The craniotomy was performed while the patient was under local anesthesia. During cortical mapping the propopofol was suspended and the remifentanil was maintained at 0.01 gamma Kg−1min−1. As the patients were carefully examined and asked about sensation, feelings, or movements, they had to be awake and cooperative with a full level of consciousness. After tumor surgery, propofol was increased from 0.8 mg Kg−1h−1to 1.5 mg Kg−1h−1and remifentanil from 0.01 gamma Kg−1 min−1to 0.04 gamma Kg−1 min−1.
Formaggio E., Storti S.F., Tramontano V., Casarin A., Bertoldo A., Fiaschi A., Talacchi A., Sala F., Toffolo G.M, & Manganotti P. (2013). Frequency and time-frequency analysis of intraoperative ECoG during awake brain stimulation. Frontiers in Neuroengineering, 6, 1.
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Publication 2013
Anesthesia Angioma, Cavernous Brain Neoplasms Consciousness Cortex, Cerebral Craniotomy Ethics Committees, Clinical Feelings Females Gamma Rays Glioma Local Anesthesia Males Meningioma Midazolam Movement Neoplasms Operative Surgical Procedures Patients Pharmaceutical Adjuvants Propofol Remifentanil
4
DBS Electrode Implantation in Globus Pallidus
Cited 8 times
In all patients, bilateral DBS electrodes were implanted in a single operation. All patients had normal brain magnetic resonance imaging (MRI). As reported elsewhere in detail (Moll et al., 2009 (link)), surgical planning comprised the delineation of a reference line connecting anterior and posterior commissure in T1-weighted MRIs as well as a direct visualization of the surgical target region on MRIs fused with stereotactic computerized tomography scans for indirect and individual targeting, respectively. All procedures and collection of recordings during DBS surgery were approved by the local ethics committee and all patients gave their written and informed consent. In all patients, the posteroventral lateral aspect of the GPi was targeted 20–22 mm lateral to the midline, 2–3 mm anterior to the mid-commissural point and 3 mm below the commissural plane. Approach angles of the planned trajectories were 25 ± 11° in the sagittal and 10 ± 5° in the frontal plane. Microelectrode-guided stereotactic implantation of DBS electrodes encompassed recordings from up to five parallel tracks (mean number of recording tracks for mapping, 4 ± 1, Micro Guide, Alpha Omega Inc., Nazareth, Israel). The used recording configuration (“BenGun”) consisted of four outer tracks arranged in a concentric array around a central trajectory aiming at the target. In all but one patient (case 10), the “BenGun” was turned 45° in respect to the standard “cross-like” configuration, taking into account the elongated morphology of the globus pallidus. Typically, antero- and postero-medial trajectories were used in addition to the central electrode—in some cases together with an additional anterolateral track. Microelectrodes (Alpha Omega Neuroprobe, Alpha Omega Inc., Nazareth, Israel) were simultaneously advanced in steps of 100–500 μm. Average tip impedance was 660 ± 290 kΩ at 1000 Hz. Recordings were started 16 ± 4 mm above the radioanatomically defined target level. In the LA group, vigilance level was continuously monitored and all patients were awake and co-operative throughout the whole recording procedure. During recordings, patients were asked to lie as still as possible with their eyes closed. Only “movement-free” recordings of spontaneous activity that were made before or after the assessment of sensorimotor responses by passive or active movements, were included in the present study. In the GA group, anaesthesia was induced with an intravenous bolus of 2 mg/kg propofol. Intravenous anaesthesia was then maintained with 4.1 ± 1.3 mg/kg/h propofol in combination with 0.2 ± 0.04 μ g/kg/min remifentanil. GA patients were ventilated via an endotracheal tube with an oxygen-air mixture and anaesthetic depth and adequacy were carefully monitored throughout the whole operation by an experienced anaesthesiologist. In contrast to LA surgeries, during which some of the patients experienced involuntary muscle spasms of their neck muscles, no spontaneous movements or signs of dystonia occurred during surgery in GA.
Moll C.K., Galindo-Leon E., Sharott A., Gulberti A., Buhmann C., Koeppen J.A., Biermann M., Bäumer T., Zittel S., Westphal M., Gerloff C., Hamel W., Münchau A, & Engel A.K. (2014). Asymmetric pallidal neuronal activity in patients with cervical dystonia. Frontiers in Systems Neuroscience, 8, 15.
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Publication 2014
Anesthesia Anesthesia, Intravenous Anesthesiologist Anesthetics Brain Dystonia Disorders Eye Globus Pallidus Magnetic Resonance Imaging Microelectrodes Movement Neck Muscles Operative Surgical Procedures Ovum Implantation Oxygen Patients Propofol Radionuclide Imaging Regional Ethics Committees Remifentanil Smooth Muscles Spasm Wakefulness X-Ray Computed Tomography
5
Pediatric Sedation and Analgesia Potency Comparison
Cited 7 times

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Publication 2011
Analgesics Analgesics, Opioid Benzodiazepines Body Weight Clonazepam Codeine Phosphate Critical Illness Diazepam Ethnicity Fentanyl Citrate Hydrochloride, Methadone Hydromorphone Hydrochloride Lorazepam Management, Pain Mechanical Ventilation Midazolam Morphine Opioids Oxycodone Patient Discharge Patients Psychotropic Drugs Remifentanil Sedatives Sulfate, Morphine

Most recents protocols related to «Remifentanil»

1
Standardized Anesthesia and Multimodal Analgesia Protocols
In Yuan et al study,[29 (link)] patients received standardized general anesthesia and basic analgesic protocol. Intraoperatively, all patients received general anesthesia which was induced by sufentanil 0.5 μg/kg, midazolam 0.04 mg/kg, propofol 1 to 2 mg/kg, and Cisatracurium 2 μg/kg intravenously, followed by continuous intravenous infusion of remifentanil 0.1 to 0.3 μg/(kg·min), propofol 2 to 5 mg/(kg·hr) and inhalation of sevoflurane to maintain anesthesia. Since postoperative day 1, the protocol of oral celecoxib restarted till postoperative 3 weeks when the patients came back to the hospital for taking out the stitches. In Yadeau et al 2016 study,[6 (link)] patients received a standardized anesthetic and multimodal analgesic protocol. In Yadeau et al 2022 study,[28 (link)] patients received a standard intraoperative and postoperative multimodal anesthetic protocol: a spinal-epidural (subarachnoid mepivacaine, 45–60 mg); adductor canal block (ultrasound-guided; 15 cc bupivacaine, 0.25%, with 2 mg preservative-free dexamethasone). For postoperative pain management, patients were scheduled to receive the study medication once daily for 14 days; 4 doses of 1000 mg IV acetaminophen every 6 hours followed by 1000 mg oral acetaminophen every 8 hours; 4 doses of 15 mg IV ketorolac followed by 15 mg meloxicam every 24 hours; and 5 to 10 mg oral oxycodone was given as needed for pain. Patients could have pain medications adjusted as indicated. In Koh et al study,[12 (link)] all patients had a postoperative intravenous patient-controlled anesthesia (PCA) pump that administered 1 mL of a 100-mL mixture containing 2000 mg of fentanyl on demand. In Kim et al study,[27 ] all patients received intravenous PCA encompassing delivery of 1 mL of a 100 mL solution containing 2000 µg of fentanyl postoperatively. In Ho et al study,[26 (link)] patients were routinely offered a single shot spinal anesthesia consisting of an intrathecal dose of bupivacaine 10 to 12.5 mg with fentanyl 10 mg. After surgery, pain treatment consisted of PCA with intravenous injection of morphine. The settings were 1 mg bolus, 5 minutes lockout time, and a maximum hourly limit of 8 mg. All patients were also given acetaminophen 1 g 6 hourly.
Zhang L.K., Li Q., Fang Y.F, & Qi J.W. (2023). Effect of duloxetine on pain relief after total knee arthroplasty: A meta-analysis of randomized controlled trials. Medicine, 102(10), e33101.
Publication 2023
Acetaminophen Analgesics Anesthesia Anesthesia, Intravenous Anesthetics Bupivacaine Cardiac Arrest Celecoxib cisatracurium Dexamethasone Fentanyl General Anesthesia Inhalation Intravenous Infusion Ketorolac Management, Pain Meloxicam Mepivacaine Midazolam Morphine Multimodal Imaging Obstetric Delivery Operative Surgical Procedures Oxycodone Pain Pain, Postoperative Patients Pharmaceutical Preparations Pharmaceutical Preservatives Propofol Pulp Canals Remifentanil Sevoflurane Spinal Anesthesia Subarachnoid Space Sufentanil Ultrasonography
2
Anesthetic Considerations for Deep Brain Stimulation
The anesthetic method was determined mainly according to the patients' preferences. Whereas, patients who were incapable of enduring awake DBS, including those with extreme anxiety, reduced cooperation, severe convulsions and difficult breathing, were operated under GA. We also showed reasons for the patients who were operated under GA in Supplementary Table 1. According to the anesthetic method applied, patients were assigned to LA group and GA group. In LA group, patients received local scalp anesthesia with 0.5% ropivacaine and kept conscious without sedation during MER and electrode implantation. In GA group, patients were administered a bolus of 2 mg/kg BW propofol and 1 mg/kg BW remifentanil for induction. Then, anesthesia was maintained at 2 mg/kg BW propofol and 1 mg/kg BW remifentanil by a target-controlled infusion (TCI) system. Bispectral index (BIS) was applied to monitor the depth of anesthesia. The infusion of anesthetics was adjusted before MER and BIS was maintained at 40–60 to ensure the recognition of STN signals.
Qian K., Wang J., Rao J., Zhang P., Sun Y., Hu W., Hao J., Jiang X, & Fu P. (2023). Intraoperative microelectrode recording under general anesthesia guided subthalamic nucleus deep brain stimulation for Parkinson's disease: One institution's experience. Frontiers in Neurology, 14, 1117681.
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Publication 2023
Anesthesia Anesthetics Anxiety Conscious Sedation Local Anesthesia Ovum Implantation Patients Propofol Remifentanil Ropivacaine Scalp Seizures
3
Multimodal Pain Management for Postoperative Care
All patients were consecutively recruited on the day before surgery. After written informed consent was obtained, baseline questionnaires were completed. Follow-ups after surgery for pain evaluation were performed on postoperative days (POD) 1, 3, 7, 14, 21, and 30 and monthly thereafter until pain resolution was reached or up to 6 months after surgery; the sessions were conducted by face-to-face interviews during the hospital stay or telephone interviews after discharge. Loss to follow-up was defined as the patient not being contacted during two consecutive follow-ups.
A standard perioperative pain management protocol was performed. Multimodal analgesia during surgery included the following: 1) corticosteroids, such as intravenous injection of methylprednisolone 40–80 mg before induction; 2) continuous infusion of dexmedetomidine at a rate of 0.4–0.6 μg/kg/h until incision closure; 3) short-acting opioids, including intermittent intravenous injection of sufentanil with a total dose of 0.5–1.0 μg/kg and continuous infusion of remifentanil 0.1–0.2 μg/kg/min until the end of surgery; and 4) flurbiprofen 100 mg or parecoxib 40 mg intravenously administered before the end of surgery when no contraindication presented. At the end of surgery, patient-controlled intravenous analgesia (PCIA) with sufentanil was provided to each patient for at least 72 hours. The PCIA device was initially set to deliver sufentanil at a rate of 2 μg/hour (solution 1 μg/ml) and a bolus of sufentanil 3 μg on request with a lockout time of 15 minutes. Background infusion was stopped if the worst pain score was <= 3 or opioid-related side effects (such as nausea and vomiting and dizziness) were reported during follow-ups. If severe opioid-related side effects persisted despite pharmacological treatment, PCIA was stopped at the request of the patient.
In wards, nonsteroidal anti-inflammatory drugs or COX-2 inhibitors were used as needed based on the surgeons’ preference. If patients reported pain with neuropathic characteristics, such as numbness and burning, gabapentin was added. Immediate-release oxycodone (5 mg) or tramadol (100 mg) was administered orally for rescue analgesia. Oral sustained-release oxycodone (5 mg every 12 hours) or a transdermal fentanyl patch (25 μg/hour for 72 hours) was provided for persistent severe pain after cessation of PCIA. Pain consultations were held when necessary.
Zhang Q., Wu Y., Hong S, & Feng Y. (2023). Trajectory of worst pain within the first two weeks following pelvic and sacral tumor surgery and long-term outcome: a pilot observational prospective cohort study. BMC Anesthesiology, 23, 73.
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Publication 2023
Adrenal Cortex Hormones Analgesics, Opioid Anti-Inflammatory Agents, Non-Steroidal ARID1A protein, human Cyclooxygenase 2 Inhibitors Dexmedetomidine Face Fentanyl Flurbiprofen Gabapentin Management, Pain Medical Devices Methylprednisolone Multimodal Imaging Nausea Neuralgia Operative Surgical Procedures Opioids Oxycodone Pain Pain Measurement parecoxib Patient-Controlled Analgesia Patients Pharmacotherapy Remifentanil Sufentanil Surgeons Tramadol Transdermal Patch
4
Evaluating Analgesic Efficacy in Rat Pain Models
Each experiment was performed on a separate cohort of rats. For experiments
examining carrageenan effects using the Hargreaves and HET methods, data were
analysed separately for the left (carrageenan-treated) and right (control)
hindpaw. For experiments involving the remifentanil withdrawal pain model,
threshold values from both hindpaws of each rat were averaged, since this model
was previously shown to induce generalized mechanical
hypersensitivity.24 (link) Statistical analyses were
performed with GraphPad Prism (GraphPad Software, USA). For all experiments, a
two-way ANOVA was used to determine the significance of the session × treatment
interaction. Significant interactions were followed-up by Sidak’s multiple
comparisons tests, which were used to detect significant differences between
baseline and test sessions, and between conditions during the test session. In
experiments comparing the efficacy of morphine doses in alleviating the effects
of carrageenan treatment, the carrageenan effect was calculated as the
difference between baseline and test sessions for the carrageenan-treated
hindpaw. Effects sizes were calculated for the vehicle, 1 mg/kg, and 3 mg/kg
groups; since the 0.5 mg/kg group was similar to the vehicle group in all tests
(see Results), it was not included in this analysis. A one-way ANOVA, followed
by Sidak’s multiple comparisons test, was used to compare between effect sizes
for each test (Hargreaves, RTPA, and HET) separately. All data are reported as
mean ± SEM, and p values <0.05 are considered statistically
significant.
Hogri R., Baltov B., Drdla-Schutting R., Mussetto V., Raphael H., Trofimova L, & Sandkühler J. (2023). Probing pain aversion in rats with the “Heat Escape Threshold” paradigm. Molecular Pain, 19, 17448069231156657.
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Publication 2023
Alteplase Carrageenan Morphine neuro-oncological ventral antigen 2, human Pain prisma Remifentanil
5
Anesthetic Management for Thoracic Surgery
All patients received general anesthesia, either alone or in combined with regional nerve block (including paravertebral nerve block, epidural anesthesia, and intercostal nerve block.) according to the type of surgery. Patients underwent lobectomy or sublobectomy according to surgeon’s comprehensive evaluation based on patient’s condition.
Anesthesia induction used propofol and/or etomidate, sufentanil, and rocuronium or cisatracurium. Anesthesia maintenance used sevoflurane or propofol combined with remifentanil or sufentanil. Rocuronium or cisatracurium was used to maintain muscle relaxation. Supplemental drugs such as flurbiprofen axetil were administered when necessary. The aim was to maintain BIS 40-60, blood pressure within 20% of baseline, and temperature 36-37°C.
Double-lumen endotracheal tube of sizes Ch33-39 was used for lung isolation according to patient height. The ventilation mode was volume control mode with 6-8 ml/kg of tidal volume (TV) during two-lung ventilation and 5-6 ml/kg during one-lung ventilation (OLA), and 0-5 cmH2O of positive end-expiratory pressure (PEEP), and 12-20 breaths/min of respiratory rates. The aim was to maintain PETCO2 35-45 mmHg and SpO2 ≥92%. At the end of anesthesia, neostigmine was used to antagonize muscular relaxant before extubation.
Fluid infusion was administrated with crystalloid at a rate of 4–6 mL/kg-1h-1. Colloids or blood product was used according to anesthesiologist’s comprehensive evaluation based on patient’s condition. Patient-controlled intravenous analgesia was used after surgery for postoperative analgesia to maintain numeric rating scales (NRS) ≤ 3 scores.
Jin F., Liu W., Qiao X., Shi J., Xin R, & Jia H.Q. (2023). Nomogram prediction model of postoperative pneumonia in patients with lung cancer: A retrospective cohort study. Frontiers in Oncology, 13, 1114302.
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Publication 2023
Anesthesia Anesthesiologist BLOOD Blood Pressure cisatracurium Colloids Epidural Anesthesia Etomidate flurbiprofen axetil General Anesthesia isolation Lung Management, Pain Muscle Tissue Neostigmine Nerve Block One-Lung Ventilation Operative Surgical Procedures Patient-Controlled Analgesia Patients Pharmaceutical Preparations Positive End-Expiratory Pressure Propofol Relaxations, Muscle Remifentanil Respiratory Rate Rocuronium Saturation of Peripheral Oxygen Sevoflurane Solutions, Crystalloid Sufentanil Surgeons Tidal Volume Tracheal Extubation

Top products related to «Remifentanil»

1
Ultiva by GlaxoSmithKline
Sourced in United Kingdom, Sweden, Belgium
Ultiva is a sterile, white to off-white, lyophilized powder for intravenous administration. Its active ingredient is remifentanil hydrochloride, a rapid-acting, potent opioid analgesic. Ultiva is indicated for the induction and maintenance of anesthesia and for the reduction of postoperative pain.
2
Remifentanil by GlaxoSmithKline
Sourced in United Kingdom, United States
Remifentanil is a synthetic opioid analgesic medication used in anesthesia and pain management. It is a potent, ultra-short-acting drug that can be administered as an infusion or bolus injection. The core function of Remifentanil is to provide rapid-onset, controllable pain relief during medical procedures or in critical care settings.
3
Ultiva by Johnson & Johnson
Sourced in Japan
Ultiva is a lab equipment product manufactured by Johnson & Johnson. It is a powerful intravenous anesthetic agent used for the induction and maintenance of general anesthesia.
4
Orchestra base primea by Fresenius
Sourced in France, Germany
The Orchestra Base Primea is a laboratory equipment product offered by Fresenius. It is designed to perform essential functions within a laboratory setting. The core function of this product is to provide a reliable and versatile platform for various laboratory tasks, but a detailed description cannot be provided while maintaining an unbiased and purely factual approach.
5
Sedline by Masimo
Sourced in United States
SedLine is a patient brain function monitoring system that provides key data about a patient's brain activity during surgical procedures. It uses advanced signal processing to continuously measure and display brain activity throughout the perioperative period.
6
Propofol by Fresenius
Sourced in Germany, Austria, China, United States, United Kingdom, Belgium, Sweden, Israel
Propofol is a pharmaceutical product used as a general anesthetic and sedative. It is a sterile, nonpyrogenic injectable emulsion that contains the active ingredient propofol and other inactive ingredients. Propofol is administered intravenously and is used to induce and maintain general anesthesia, as well as for sedation in intensive care unit (ICU) settings.
7
Remifentanil by Merck Group
Sourced in Belgium, United States
Remifentanil is a synthetic opioid analgesic used as a general anesthetic and sedative. It is a potent, ultra-short-acting, and selective μ-opioid receptor agonist. Remifentanil is primarily used in hospital and clinical settings, administered intravenously, to provide pain relief and sedation during surgical procedures.
8
Intellivue mp50 by Philips
Sourced in Germany, United States, Netherlands
The IntelliVue MP50 is a patient monitor that provides comprehensive physiological data monitoring. It is designed to measure and display a variety of patient vital signs, such as heart rate, blood pressure, and oxygen saturation. The monitor is intended for use in healthcare settings, such as hospitals and clinics, to support patient care and monitoring.
9
Dimethyl sulfoxide (dmso) by Merck Group
Sourced in United States, Germany, United Kingdom, China, Italy, Sao Tome and Principe, France, Macao, India, Canada, Switzerland, Japan, Australia, Spain, Poland, Belgium, Brazil, Czechia, Portugal, Austria, Denmark, Israel, Sweden, Ireland, Hungary, Mexico, Netherlands, Singapore, Indonesia, Slovakia, Cameroon, Norway, Thailand, Chile, Finland, Malaysia, Latvia, New Zealand, Hong Kong, Pakistan, Uruguay, Bangladesh
DMSO is a versatile organic solvent commonly used in laboratory settings. It has a high boiling point, low viscosity, and the ability to dissolve a wide range of polar and non-polar compounds. DMSO's core function is as a solvent, allowing for the effective dissolution and handling of various chemical substances during research and experimentation.
10
Diprivan by AstraZeneca
Sourced in United Kingdom, Italy, Japan, China, Turkiye
Diprivan is a laboratory equipment product manufactured by AstraZeneca. It is an intravenous anesthetic agent primarily used for the induction and maintenance of general anesthesia. The core function of Diprivan is to provide a controlled and safe administration of anesthesia in clinical settings.

More about "Remifentanil"

Remifentanil is a short-acting, potent opioid analgesic that is commonly used in surgical procedures to provide pain relief and sedation.
It is rapidly metabolized by nonspecific esterases, resulting in a short duration of action and rapid recovery.
Remifentanil, also known by its brand name Ultiva, is often used for anesthesia induction and maintenance.
The use of Remifentanil requires careful monitoring due to the risk of respiratory depression and other adverse effects.
PubCompare.ai's powerful tool can help streamline Remifentanil research by enhancing reproducibility and accuracy, locating relevant protocols from literature, pre-prints, and patents, and leveraging AI-driven comparisons to identify the best protocols and products.
Remifentanil is commonly used in conjunction with other anesthetic agents, such as Propofol (Diprivan) and sedatives like SedLine.
The Orchestra Base Primea system is a powerful tool that can be used to administer and monitor the administration of Remifentanil and other anesthetic agents.
By utilizing the insights and tools provided by PubCompare.ai, researchers can optimize their Remifentanil studies, improve the accuracy and reproducibility of their findings, and streamline the research process.
This can lead to more efficient and effective Remifentanil research, ultimately benefiting healthcare professionals and patients.