For analysis of LFP signals, a total of 35 mice were used, 13 for the EE-OLD group, 10 for the SC-OLD group, 6 for the EE-YOUNG group and 6 for the SC-YOUNG group. For comparing the results of Fourier analysis (Figure 3 and Figure S1 ), Three-Way ANOVA followed by Holm-Sidak post-hoc test was used, with factors “rearing” (with levels EE and SC), “age” (with levels AGED and YOUNG) and “cortical area” (with levels A1 and V1). For comparing the results of Cross correlation analysis (Figure 4 and Figure S2 ), Two-Way ANOVA followed by Holm-Sidak post-hoc test was used.
For Western blots on vGluT-1 and vGAT (Figure5 ), a total of 26 mice were used, 12 for the EE-OLD group, 9 for SC-OLD group and 5 for the SC-YOUNG group. Statistical significance was assessed using One-Way ANOVA followed by Tukey post-hoc test.
For Western blots on amyoid-β oligomers and neprilysin (Figures6 , 7 ), a total of 36 mice were used, 22 for the EE-OLD group and 14 for the SC-OLD group. Statistical significance was assessed using Student's t-test.
All the analyses have been performed using the SigmaPlot 12 software (SyStat Software, USA).
Data are presented as mean ± s.e.m.
For Western blots on vGluT-1 and vGAT (Figure
For Western blots on amyoid-β oligomers and neprilysin (Figures
All the analyses have been performed using the SigmaPlot 12 software (SyStat Software, USA).
Data are presented as mean ± s.e.m.
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