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Tween 80

Tween 80 is a nonionic surfactant commonly used in pharmaceuticals, cosmetics, and biochemical applications.
It is derived from polyethoxylated sorbitan and oleic acid, and has a hydrophile-lipophile balance (HLB) value of 15, making it soluble in both aqueous and organic media.
Tween 80 is known for its ability to enhance the solubility, stability, and bioavailabilty of various drug formulations.
It is also utilized in cell culture media, protein purification, and as a emulsifier or detergent in a variety of research and industrial processes.
Tween 80 has a low toxicity profile and is generally considered safe for human use, though occassional skin irritation or allergic reactions may occur in some individuals.

Most cited protocols related to «Tween 80»

1
Genetic Manipulation and Melanoma Induction in Mice
Cited 77 times
BRafCA, Tyr::CreER and Ptenlox4-5 mice were genotyped as previously described 17 (link),20 (link),24 (link). Cre-mediated conversion of BRafCA to BRafVE and the deletion of exons 4 and 5 of Pten were assessed by PCR as previously described. Topical administration of 4-hydroxytamoxifen (4-HT) was performed by preparing a 25-50mg/ml (65-130mM) solution of 4-HT (70% Z-isomer, Sigma) in DMSO and applying enough solution to wet the right ear, right flank and tail with a small paint brush on post-natal days 2, 3, and 4. For localized melanoma induction on the back skin, adult (6-8 weeks of age) mice were treated topically with 1-2 μl of 1.9mg/ml (5mM) 4-HT at 6-8 weeks of age using a similar protocol. Generalized induction in adult mice was performed by intra-peritoneal injection of 1mg of tamoxifen/40g mouse on 3 consecutive days. In this case tamoxifen was prepared as a 10mg/ml suspension in peanut oil. PD352901 was dissolved in 0.5%(w/v) Hydroxy-propyl-methylcellulose, 0.2%(v/v) Tween 80 (Sigma) and administered to mice daily by oral gavage at a dose of 12.5mg/kg. Rapamycin (LC Laboratories, Woburn, MA) was suspended in 0.5%(w/v) methylcellulose and administered to mice daily by oral gavage at a dose of 7.5mg/kg. Control animals in the melanoma prevention studies were administered with the relevant solvent. Tissues were prepared for analysis as previously described 17 (link),20 (link)
Dankort D., Curley D.P., Cartlidge R.A., Nelson B., Karnezis A.N., Damsky WE J.r., You M.J., DePinho R.A., McMahon M, & Bosenberg M. (2009). BRafV600E cooperates with Pten silencing to elicit metastatic melanoma. Nature genetics, 41(5), 544-552.
Publication 2009
Administration, Topical Adult Animals Deletion Mutation Exons Familial Atypical Mole-Malignant Melanoma Syndrome hydroxytamoxifen Hypromellose Injections, Intraperitoneal Isomerism Melanoma Methylcellulose Mice, House Peanut Oil PTEN protein, human Sirolimus Solvents Sulfoxide, Dimethyl Tail Tamoxifen Tissues Tube Feeding Tween 80
2
Influenza Virus Plaque Assay Optimization
Cited 74 times
One hour after infecting the cell monolayers with 30–50 plaque forming units of the virus in 1 ml of maintenance medium without trypsin, we removed the virus inoculum, covered the cells with 3 ml of the different overlay media and incubated cultures at 35°C in 5% CO2 atmosphere. In the case of MC and Avicel overlays, care was taken not to disturb the plates during the incubation period in order to avoid formation of non-even plaques. After three days of incubation, we removed the overlays and fixed the cells. Agar overlay was removed using metal spatula; MC, Avicel, and liquid overlays were removed by suction. The cells were fixed with 4% paraformaldehyde solution in MEM for 30 min at 4°C and washed with PBS. All subsequent treatments of the cells were performed at room temperature. We permeabilized the cells and simultaneously blocked residual aldehyde groups by incubating the cells for 10–20 min with 1 ml/well of solution containing 0.5 % Triton-X-100 and 20 mM glycine in PBS. We immuno-stained virus-infected cells by incubating for 1 hr with monoclonal antibodies specific for the influenza A virus nucleoprotein (kindly provided by Dr. Alexander Klimov at Centers for Disease Control, USA) followed by 1 hr incubation with peroxidase-labeled anti-mouse antibodies (DAKO, Denmark) and 30 min incubation with precipitate-forming peroxidase substrates. Solution of 10% normal horse serum and 0.05% Tween-80 in PBS was used for the preparation of working dilutions of immuno-reagents. We washed the cells after the primary and secondary antibodies by incubating them three times for 3–5 min with 0.05% Tween-80 in PBS. As peroxidase substrates, we employed either ready to use True Blue™ (KPL) or solution of aminoethylcarbazole (AEC, Sigma) (0.4 mg/ml) prepared in 0.05 M sodium acetate buffer, pH 5.5 and containing 0.03% H2O2. Stained plates were washed with tap water to stop the reaction and dried. In the case of True Blue staining, which is relatively unstable in water solutions, plates were dried inverted in order to minimize bleaching. Stained plates were scanned on a flat bed scanner and the data were acquired by Adobe Photoshop 7.0 software.
As an alternative to immuno-staining, in some experiments we revealed plaques as areas of destroyed cells. To this end, after removing the overlays, we stained the cells with 1% crystal violet solution in 20% methanol in water.
Matrosovich M., Matrosovich T., Garten W, & Klenk H.D. (2006). New low-viscosity overlay medium for viral plaque assays. Virology Journal, 3, 63.
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Publication 2006
Agar Aldehydes Anti-Antibodies Antibodies Atmosphere Avicel Buffers Dental Plaque Equus caballus Glycine Metals Methanol Monoclonal Antibodies Mus NP protein, Influenza A virus paraform Peroxidase Peroxide, Hydrogen Senile Plaques Serum Sodium Acetate Suction Drainage Technique, Dilution Triton X-100 true blue Trypsin Tween 80 Violet, Gentian Virus
3
Mycobacterium tuberculosis Strain H37Rv
Cited 34 times
MTB H37Rv was used for all experiments with the single exception of one experiment performed in M. smegmatis (Supplementary Fig. 21). This MTB strain was fully sequenced by the Broad Institute (GI:397671778). For Chip-Seq, cells were cultured in Middle brook 7H9 with ADC (Difco), 0.05% Tween 80, and 50 µg ml−1 hygromycin B at 37 °C with constant agitation and induced with 100 ng ml−1 anhydrotetracycline (ATc) during mid-log-phase growth, and ChIP was performed using a protocol optimized for mycobacteria and related Actinomycetes. For the hypoxia and re-aeration time-course, bacilli were cultured in bacteriostatic oxygen-limited conditions (1% aerobic O2 tension) for seven days, followed by re-aeration. Bacteria were cultured in Sauton’s medium without detergent or exogenous lipid source. Profiling samples were collected as described in the Supplementary Text. All data available at http://TBDB.org. Expression data also available at GEO (accession number GSE43466).
Galagan J.E., Minch K., Peterson M., Lyubetskaya A., Azizi E., Sweet L., Gomes A., Rustad T., Dolganov G., Glotova I., Abeel T., Mahwinney C., Kennedy A.D., Allard R., Brabant W., Krueger A., Jaini S., Honda B., Yu W.H., Hickey M.J., Zucker J., Garay C., Weiner B., Sisk P., Stolte C., Winkler J.K., Van de Peer Y., Iazzetti P., Camacho D., Dreyfuss J., Liu Y., Dorhoi A., Mollenkopf H.J., Drogaris P., Lamontagne J., Zhou Y., Piquenot J., Park S.T., Raman S., Kaufmann S.H., Mohney R.P., Chelsky D., Moody D.B., Sherman D.R, & Schoolnik G.K. (2013). The Mycobacterium tuberculosis regulatory network and hypoxia. Nature, 499(7457), 178-183.
Publication 2013
Actinomycetes anhydrotetracycline Bacteria Bacteria, Aerobic Cells Chromatin Immunoprecipitation Sequencing Culture Media Detergents DNA Chips Hygromycin B Hypoxia Lacticaseibacillus casei Lipids Mycobacterium Strains Tween 80
4
Mycobacterial and E. coli Culture Conditions
Cited 32 times

M. smegmatis mc2155 [72] (link), M. tuberculosis H37Rv and Escherichia coli NEB-10β (New England Biolabs UK Ltd) were used in this work. M. smegmatis and M. tuberculosis were grown on Middlebrook 7H11 agar medium (BD Diagnostics) supplemented with 0.5% glycerol and 10% oleic acid albumin-dextrose-catalase (OADC) (BD Diagnostics). When required, filter-sterilised luciferin was added at a final concentration of 0.157 mM. Liquid cultures of M. smegmatis and M. tuberculosis were grown either in Middlebrook 7H9 broth (BD Diagnostics) containing 0.05% Tween 80 (Sigma) and 10% albumin-dextrose-catalase (ADC) enrichment (BD Diagnostics), or (for M. smegmatis Gluc assays) in Luria-Bertani (LB) medium with 0.05% Tween. LB medium was preferred for the Gluc assays because the background of coelenterazine was 100 times lower in that medium than in 7H9 broth. LB medium was used for culturing E. coli. All the strains were grown at 37°C. The following antibiotics were added when appropriate: ampicillin [100 µg ml−1 (Sigma)], hygromycin B [150 µg ml−1 (Invitrogen)] and kanamycin [25 µg ml−1, for mycobacteria, 50 µg ml−1 for E. coli (Sigma)].
Andreu N., Zelmer A., Fletcher T., Elkington P.T., Ward T.H., Ripoll J., Parish T., Bancroft G.J., Schaible U., Robertson B.D, & Wiles S. (2010). Optimisation of Bioluminescent Reporters for Use with Mycobacteria. PLoS ONE, 5(5), e10777.
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Publication 2010
Agar Albumins Ampicillin Antibiotics, Antitubercular Biological Assay Catalase coelenterazine Diagnosis Escherichia coli Glucose Glycerin Hygromycin B Kanamycin Luciferins Mycobacterium Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv Oleic Acid Strains Tween 80 Tweens
5
Mosquito Saliva Titers and CHIKV Detection
Cited 27 times
Twenty females were used every 1–2 days until day 14 pi. Females were chilled, and wings and legs were removed and discarded. Proboscis was inserted into 1 µL micropipette (microcaps®, Drummond Scientific Company, PA, USA) filled with 1 µL of Fetal Bovine Serum (FBS). One µL of 1% pilocarpine, an analogue of the acetylcholine, prepared in PBS at 0.1% Tween 80, was applied on the thorax to stimulate salivation. After 45 min, medium containing the saliva was expelled under pressure into 1.5 mL tubes containing 29 µL of DMEM (Dulbecco's modified Eagle's medium) supplemented with 10% FBS. These 30 µL were added, diluted or undiluted, to monolayers of Vero cells to detect infectious particles by the plaque assay technique. Cells were incubated for 3 days at 37°C under an overlay consisting of DMEM 2×, 2% FBS, antibiotics and 1% Indubiose (IBF Biotechnics). Plaques were counted after staining with a solution of crystal violet (0.2% in 10% formaldehyde and 20% ethanol). The titer of infectious particles per saliva was expressed as PFU/mL. One assay was achieved for each mosquito species.
In addition to collection and titration of saliva, 5 females at different days pi were tested for the presence of CHIKV on head squashes to evaluate the relation between the presence of CHIKV in saliva and head squashes positive by IFA.
Dubrulle M., Mousson L., Moutailler S., Vazeille M, & Failloux A.B. (2009). Chikungunya Virus and Aedes Mosquitoes: Saliva Is Infectious as soon as Two Days after Oral Infection. PLoS ONE, 4(6), e5895.
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Publication 2009
Acetylcholine Antibiotics Biological Assay Cells Chest Cucurbita Culicidae Dental Plaque Ethanol Females Fetal Bovine Serum Formaldehyde Head Infection Leg Pilocarpine Pressure Saliva Salivation Senile Plaques Titrimetry Tween 80 Vero Cells Violet, Gentian

Most recents protocols related to «Tween 80»

1
Microwave-Assisted Decontamination of Bacillus Spores
Not available on PMC !

Example 2

Thuricide BT Caterpillar Control (Southern Ag) was used as the source of viable Bacillus thuringiensis spores (6 million spores/mg). A dilution series was produced from Thuricide BT to show that the material is viable and could be readily cultured on Petrifilm plates. Three DEE chemical compositions were evaluated: (1) about 0.06 M copper (II) chloride in water, (2) about 1 wt.-% surfactant and about 10 wt.-% PCSR in water, and (3) about 1 wt.-% surfactant and about 1 wt.-% PCSR in water. OxiClean was used as the PCSR and Tween 80 as the surfactant. During testing of each DEE composition, the DEE composition was added to the spores to yield a 1:100 dilution of spores and exposed to 2.45 GHz microwave radiation for about 10 s. After exposure, the cells were centrifuged and washed to remove the DEE composition and then plated on Petrifilm and cultured for 24 h at 30° C. When using each of the three DEE compositions shown above, the decontamination method destroyed BT spores at 6-7 log kill levels and demonstrated the efficacy of bleach-free treatments.

US11872322B2. Microwave assisted methods and systems for surface decontamination (2024-01-16). Zeteo Tech, Inc. [US]. Inventors: Thomas McCreery [US], Wayne A. Bryden [US].
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Patent 2024
Bacillus thuringiensis Cells chemical composition Chlorides Copper Decontamination Microwaves Spores Surface-Active Agents Technique, Dilution Thuricide Tween 80
2
Microwave Inactivation of Penicillium roqueforti Spores
Not available on PMC !

Example 3

Penicillium roqueforti spores were suspended in water. Four DEE chemical compositions were evaluated: (1) 0.06 M copper (II) ions in water, (2) 1 wt.-% surfactant and 10 wt.-% PCSR, (3) 1 wt.-% surfactant and 1 wt.-% PCSR, and (4) 0.5 wt.-% bleach. OxiClean was used as the PCSR and Tween 80 as the surfactant. Clorox was used as bleach. Each DEE composition was added to 0.1 mg/ml suspension of mold spores and exposed to 2.45 GHz microwave for 10 s. After exposure, the cells were centrifuged, washed to remove the DEE chemicals and then plated on Petrifilm and cultured. With the DEE composition 0.06 M copper (II) ions in water and 1 wt.-% surfactant and 10 wt.-% sodium percarbonate, a 6-7 log reduction in P. roqueforti spores (6-7 log kill levels) was realized.

US11872322B2. Microwave assisted methods and systems for surface decontamination (2024-01-16). Zeteo Tech, Inc. [US]. Inventors: Thomas McCreery [US], Wayne A. Bryden [US].
Full text: Click here
Patent 2024
Cells chemical composition Clorox Copper Fungus, Filamentous Ions Microwaves Penicillium roqueforti sodium percarbonate Spores Surface-Active Agents Tween 80
3
Evaluating UBX1967 in Mouse OIR Model
Not available on PMC !

Example 6

The efficacy of model compound UBX1967 was studied in the mouse oxygen-induced retinopathy (OIR) model, which provides an in vivo model of retinopathy of prematurity (ROP) and diabetic retinopathy.

C57Bl/6 mouse pups and their CD1 foster mothers were exposed to a high oxygen environment (75% 02) from postnatal day 7 (P7) to P12. At P12, animals were injected intravitreally with 1 μl test compound (200, 20, or 2 uM) formulated in 1% DMSO, 10% Tween-80, 20% PEG-400, and returned to room air until P17. Eyes were enucleated at P17 and retinas dissected for either vascular staining or qRT-PCR. To determine avascular or neovascular area, retinas were flatmounted, and stained with isolectin B4 (IB4) diluted 1:100 in 1 mM CaCl2. For quantitative measurement of senesecence markers (e.g., Cdkn2a, Cdkn1a, 116, Vegfa), qPCR was performed. RNA was isolated and cDNA was generated by reverse-transcription, which was used for qRT-PCR of the selected transcripts.

FIGS. 9A and 9B show that intravitreal (IVT) administration UBX1967 resulted in statistically significant improvement in the degree of neovascularization and vaso-obliteration at all dose levels.

FIGS. 10A and 10B show the relative abundance of several transcripts associated with senescence (p16, pai1) and human disease (vegf). Treatment with UBX1967 resulted in a 58%, 35%, and 24% reduction in p16, pai1, and vegf, respectively. Senescence-associated β-galactosidase (SA-BGal) activity was reduced by 17% after administration of UBX1967.

These results show that a single ocular injection of UBX1967 can functionally inhibit pathogenic angiogenesis and promote vascular repair in this key OIR disease model. We believe that efficacy of UBX1967 in the OIR model is due to elimination of senescent cells and accompanying SASP that propagates senescence in retinal cells and promotes neovascularization of retinal vessels.

US11865123B2. Methods of inhibiting pathological angiogenesis (2024-01-09). Unity Biotechnology, Inc. [US]. Inventors: Pam Tsuruda [US], Jill Hopkins [US], Harry Sweigard [US], Yan Poon [US], Jamie Dananberg [US], Daniel Marquess [US], Nathaniel David [US].
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Patent 2024
Aftercare angiogen Animal Model Animals beta-Galactosidase Blood Vessel Cardiac Arrest CDKN1A protein, human Cellular Senescence Diabetic Retinopathy DNA, Complementary Eye Figs Homo sapiens Isolectins Mice, Inbred C57BL Mothers Mus Oxygen pathogenesis Pathologic Neovascularization polyethylene glycol 400 Retina Retinal Diseases Retinal Neovascularization Retinal Vessels Retinopathy of Prematurity Reverse Transcription SERPINE1 protein, human Sulfoxide, Dimethyl Tween 80 TXN protein, human Vascular Diseases Vascular Endothelial Growth Factors Vision
4
Synthesis of Myc-Inhibitor-1 Prodrug
Not available on PMC !

Example 9

Myc-inhibitor-1 may be synthesized (FIG. 14) by reacting 4-ethyl benzaldehyde with rhodanine in the presence of a catalytic amount of Tween-80 in potassium carbonate solution at ambient temperature. The mixture may be neutralized with 5% HCl and the precipitant may be treated with saturated NaHSO3 and re-crystallized with aqueous ethanol. This rhodanine derivative may be reacted to piperidine-mono-tert Boc and formaldehyde. Deprotection of the tert Boc in presence of TFA may produce the Myc-inhibitor-1. Finally Myc-inhibitor-1 may undergo sodium cyano borohydride mediated reductive amination with ALDO (PC) in presence of catalytic amounts of TFA to produce the Myc-rhodanine prodrug.

US11872313B2. Prodrug compositions, prodrug nanoparticles, and methods of use thereof (2024-01-16). Washington University [US]. Inventors: Gregory M. Lanza [US], Dipanjan Pan [US].
Full text: Click here
Patent 2024
Amination Anabolism benzaldehyde Catalysis Ethanol Formaldehyde piperidine potassium carbonate Prodrugs Rhodanine sodium borohydride TERT protein, human Tween 80
5
Cultivation and Preparation of Bacterial Strains
Staphylococcus aureus (S. aureus) ATCC-6538 was cultured overnight at 37 °C in tryptic soy broth (TSB) in an orbital shaker (100–120 rpm). Escherichia coli (E. coli) 8099 and methicillin-resistant S. aureus (MRSA) (ATCC-44) were grown by the same procedure but substituting TSB with lysogeny broth (LB) and tryptic soy broth (TSB) with 5 mg/L tetracycline, respectively. Bacterial strains were grown to an initial concentration of 107–109 CFU (colony forming units)/mL. Cultures were pelleted via centrifugation (10,000 × g) for 10 min, the supernatant was decanted, and the bacteria were re-suspended in phosphate buffered saline (PBS; aqueous solution of 170 mM NaCl, 3.4 mM KCl, 10.0 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.2) containing 0.05% Tween-80.
Jiang C., Dejarnette S., Chen W., Scholle F., Wang Q, & Ghiladi R.A. (2023). Color-variable dual-dyed photodynamic antimicrobial polyethylene terephthalate (PET)/cotton blended fabrics. Photochemical & Photobiological Sciences.
Publication 2023
Bacteria Centrifugation Escherichia coli Lysogeny Methicillin-Resistant Staphylococcus aureus Phosphates Saline Solution Sodium Chloride Staphylococcus aureus Infection Strains Tetracycline tryptic soy broth Tween 80

Top products related to «Tween 80»

1
Tween 80 by Merck Group
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Tween 80 is a non-ionic surfactant and emulsifier. It is a viscous, yellow liquid that is commonly used in laboratory settings to solubilize and stabilize various compounds and formulations.
2
Dimethyl sulfoxide (dmso) by Merck Group
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DMSO is a versatile organic solvent commonly used in laboratory settings. It has a high boiling point, low viscosity, and the ability to dissolve a wide range of polar and non-polar compounds. DMSO's core function is as a solvent, allowing for the effective dissolution and handling of various chemical substances during research and experimentation.
3
Methanol by Merck Group
Sourced in Germany, United States, Italy, India, United Kingdom, China, France, Poland, Spain, Switzerland, Australia, Canada, Sao Tome and Principe, Brazil, Ireland, Japan, Belgium, Portugal, Singapore, Macao, Malaysia, Czechia, Mexico, Indonesia, Chile, Denmark, Sweden, Bulgaria, Netherlands, Finland, Hungary, Austria, Israel, Norway, Egypt, Argentina, Greece, Kenya, Thailand, Pakistan
Methanol is a clear, colorless, and flammable liquid that is widely used in various industrial and laboratory applications. It serves as a solvent, fuel, and chemical intermediate. Methanol has a simple chemical formula of CH3OH and a boiling point of 64.7°C. It is a versatile compound that is widely used in the production of other chemicals, as well as in the fuel industry.
4
Glycerol by Merck Group
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Glycerol is a colorless, odorless, and viscous liquid used in various laboratory applications. It is a basic chemical compound with the molecular formula C₃H₈O₃. Glycerol is commonly used as a solvent, humectant, and stabilizer in many laboratory procedures.
5
Middlebrook 7h9 broth by BD
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Middlebrook 7H9 broth is a type of culture media used for the growth and maintenance of mycobacteria, such as Mycobacterium tuberculosis. It provides essential nutrients and growth factors required by these bacteria.
6
Tween 80 by Thermo Fisher Scientific
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Tween 80 is a non-ionic surfactant commonly used in laboratory applications. It functions as a dispersing agent, emulsifier, and wetting agent.
7
Ethanol by Merck Group
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Ethanol is a clear, colorless liquid chemical compound commonly used in laboratory settings. It is a key component in various scientific applications, serving as a solvent, disinfectant, and fuel source. Ethanol has a molecular formula of C2H6O and a range of industrial and research uses.
8
Span 80 by Merck Group
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Span 80 is a non-ionic surfactant. It is a viscous, colorless liquid. Span 80 is commonly used as an emulsifier, wetting agent, and dispersing agent in various industrial applications.
9
Fetal bovine serum (fbs) by Thermo Fisher Scientific
Sourced in United States, China, United Kingdom, Germany, Australia, Japan, Canada, Italy, France, Switzerland, New Zealand, Brazil, Belgium, India, Spain, Israel, Austria, Poland, Ireland, Sweden, Macao, Netherlands, Denmark, Cameroon, Singapore, Portugal, Argentina, Holy See (Vatican City State), Morocco, Uruguay, Mexico, Thailand, Sao Tome and Principe, Hungary, Panama, Hong Kong, Norway, United Arab Emirates, Czechia, Russian Federation, Chile, Moldova, Republic of, Gabon, Palestine, State of, Saudi Arabia, Senegal
Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
10
Acetonitrile by Merck Group
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Acetonitrile is a colorless, volatile, flammable liquid. It is a commonly used solvent in various analytical and chemical applications, including liquid chromatography, gas chromatography, and other laboratory procedures. Acetonitrile is known for its high polarity and ability to dissolve a wide range of organic compounds.

More about "Tween 80"

Tween 80, also known as polyoxyethylene (20) sorbitan monooleate or polysorbate 80, is a widely used nonionic surfactant with a versatile range of applications in the pharmaceutical, cosmetic, and biochemical industries.
Derived from polyethoxylated sorbitan and oleic acid, it possesses a hydrophile-lipophile balance (HLB) value of 15, allowing it to be soluble in both aqueous and organic media.
Tween 80's ability to enhance the solubility, stability, and bioavailability of various drug formulations makes it a valuable excipient in drug delivery systems.
It is commonly used in cell culture media, protein purification processes, and as an emulsifier or detergent in numerous research and industrial applications.
Comparable nonionic surfactants like Span 80 and DMSO are also utilized for similar purposes.
In addition to its pharmaceutical and biochemical applications, Tween 80 finds use in cosmetic formulations, where it can act as a solubilizer, emulsifier, or wetting agent.
Its low toxicity profile and generally good safety for human use, although occassional skin irritation or allergic reactions may occur in some individuals, contribute to its widespread adoption.
When working with Tween 80, it is important to consider its compatibility and potential interactions with other commonly used solvents and reagents, such as methanol, ethanol, glycerol, and acetonitrile.
Carefully selecting the appropriate Tween 80 products and optimizing protocols, as facilitated by tools like PubCompare.ai, can help ensure the reproducibility and accuracy of your research involving this versatile surfactant.