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Inulin

Inulin is a natural polyfructose found in many plants, particularly in roots and tubers.
It is a soluble dietary fiber that acts as a prebiotic, stimulating the growth of beneficial gut bacteria.
Inulin has been studied for its potential health benefits, including improved digestion, enhanced immune function, and reduced risk of chronic diseases like diabetes and obesity.
Researchers continue to explore the optimal uses of inulin in food, supplement, and therapeutic applications.
Experienve the future of inulin research today!

Most cited protocols related to «Inulin»

We recruited CKD patients (n=120) in outpatient department and healthy volunteers (n=31) from Seoul National University Hospital for the clinical study, 'Measurement of glomerular filtration rate and calculation of GFR estimates for Korean' granted by the Korean Society of Nephrology from April 2008 to February 2009. All of volunteers showed normal urinalysis and their systemic inulin clearances were greater than 60 mL/min/1.73 m2 (66.4-151.3 mL/min/1.73 m2). Inclusion criteria were as follows: 1) participants who agreed with the study and voluntarily signed on informed consent, 2) aged 18 yr or older. Exclusion criteria of this study were as follows: 1) rapid decline of renal function within 3 months, 2) edema or ascites, 3) proteinuria greater than 10 g/day or serum albumin less than 2.5 g/dL, 4) active infection, 5) coronary artery intervention i.e., coronary artery bypass graft (CABG) or percutaneous coronary intervention (PCI) within 1 yr (except stabilization after unstable angina or heart failure), 6) liver enzyme abnormality (serum AST/ALT greater than 2×upper normal range), 7) history of severe allergy like angioedema, 8) pregnant or lactating women, 9) gross hematuria, 10) oliguria less than 500 mL/day), 11) renal replacement therapy. This study was approved by the Institutional Review Board of Seoul National University Hospital (IRB No. 0701-006-193).
Publication 2010
Angina, Unstable Angioedema Ascites Congestive Heart Failure Coronary Artery Bypass Surgery Edema Enzymes Healthy Volunteers Hematuria Hypersensitivity Infection Inulin Kidney Koreans Liver Oliguria Outpatients Patients Percutaneous Coronary Intervention Renal Replacement Therapy Serum Serum Albumin Urinalysis Voluntary Workers Woman
We recruited adults aged over 18 years to sign informed consents from the Kaohsiung Medical University Hospital and the National Taiwan University Hospital. Subjects with acute renal failure, allergy to inulin, pregnancy, problems in voiding, amputation, congestive heart failure, cirrhosis with ascites, use of cimetidine or trimethoprim, oliguria, and those who had ever received any renal replacement therapy were excluded. Healthy volunteers were enrolled according to the percentage of age distribution in Taiwanese reported by the Ministry of the Interior of Taiwan. CKD was diagnosed and classified according to the K/DOQI clinical guidelines [1] (link). The ratio of the number of the CKD patients to healthy volunteers was approximately 2∶1 in this study.
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Publication 2014
Adult Amputation Ascites Cimetidine Congestive Heart Failure Healthy Volunteers Hypersensitivity Inulin Kidney Failure, Acute Liver Cirrhosis Oliguria Patients Pregnancy Renal Replacement Therapy Trimethoprim
These were carried out in a Beckman-Coulter AUC using the ProteomeLab control system at speeds and for durations selected with the aid of locally written software (SE_Speeds.xls). Radial scans were logged using Rayleigh fringe optics. Four initial and four final scans at equilibrium were logged and averaged. The final data set selected for analysis was obtained by subtraction of these two averaged data sets, removing any points near the meniscus or the cell base where evidence of re-distribution could be detected. This procedure (Ang and Rowe 2010 (link)) largely eliminates baseline gradients or other irregularities in the trace, and is superior to methods based upon use of a dummy cell. The baseline offset (E), defined as uniform in value over the selected radial interval, cannot however be eliminated in this way.
Corrected data sets have been analysed using the MultiSig programme, with a starting value for σI that should be in the region of, for choice slightly below, the expected mid-region of σ values. An initial fit using only two iterations is performed and the distribution of σ values inspected. If need be, the σI employed in the final 20-iteration fit is amended. The criterion for a ‘good’ value is that the final distribution of σ values should be wholly within the window (from 0.5σI to 4.48σI) used by the programme.
The precision of the final profile, which normally employs only 17 values for σ on the x axis, can be improved to a degree by carrying out the MultiSig fit two extra times, with two extra values for the starting value for σ producing a logarithmically interpolated set of 3 × 17 = 51 x values in the distribution. Only three iterations are now employed for each fit, to keep the total compute time manageable. An example of this modified MultiSig procedure is shown below (Fig. 3).
The radial-dependence programme MultiSig_radius is normally only employed on a system after it has been characterised using MultiSig. Thus the choice of initial σI value is trivial.
Solutions of chicory root inulin were prepared by direct dissolution of the powdered product (kindly donated by Kelloggs UK) into 90 % aqueous DMSO. Solute concentration was checked using a digital refractometer (Atago DD-5).
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Publication 2013
Cells Cichorium intybus Epistropheus Eye Fingers Inulin Meniscus Plant Roots Radionuclide Imaging Radius Sulfoxide, Dimethyl

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Publication 2013
Amylopectin Bacteria Carbohydrates Culture Media, Conditioned Glucose Inulin levan Phosphates Saline Solution Sterility, Reproductive Vision Xylans
The average population intake aims (Joint WHO/FAO consultation, 2003 ) have served as the starting point for developing criteria to evaluate food products according to their nutrient content. However, the range of fat, salt, added sugar, fibre and other nutrients between foods and beverages is far too great to create one set of criteria for all food products. Thus, product grouping is needed (Scarborough et al., 2007 (link), 2010 (link)) to assure alignment with the aims of the International Choices Programme: to help consumers choose within a product group and to stimulate producers to improve the nutrient composition. This can only be achieved if criteria are separately set for different product groups—such as fats and beverages, rather than with a single set of criteria that compares foods across the food supply (Rayner et al., 2005 ; Drewnowski and Fulgoni, 2008 (link); Katz et al., 2010 (link)).
Nutrient criteria have been developed for trans-fatty acids, saturated fatty acids, sodium and added sugars, because high intakes of these nutrients negatively affect health. The nutrient definitions and related health risks are provided in Table 1. The focus is not only on limiting the intake of nutrients with a negative impact on health, but also on ensuring the intake of essential and beneficial nutrients. To achieve this, a distinction has been made between basic foods and discretionary foods. Basic food product groups were based on product group classifications from food-based dietary guidelines used in more than 20 countries worldwide (see legend to Table 2), which significantly contribute to the intake of essential and beneficial nutrients (for example, vitamins, minerals) and water. Discretionary product groups do not significantly contribute to the intake of beneficial nutrients. They are included because they are eaten frequently, are important sources of trans-fatty acids, saturated fatty acids, sodium, added sugar and energy, and therefore targets for product innovation.
An emphasis on healthy choices in basic product groups is encouraged by setting the criteria for discretionary foods at a more restrictive level than for basic foods. This is explained below. Table 2 (second column) provides an overview of all product groups.
Fibre was the subject of much debate. Indeed, manufacturers often add artificial or isolated fibres such as inulin as a ‘beneficial nutrient' to many foods. However, the effects on health of these isolated fibres are inconclusive (Cummings et al., 2009 (link)), and these purified fibres do not provide the micronutrients and phytochemicals that are present in sources of naturally occurring fibre, such as whole grains (Pascoe and Fulcher, 2008 ). The significance of this in terms of public health is great for countries such as Mexico, where tortillas represent around a quarter of the calories consumed (Popkin, 2008 ). Therefore, to promote fibre intake, a fibre criterion was added for relevant product groups. In line with the evidence, and to ensure sufficient micronutrient intake, the source of fibre must originate from the actual ingredients of the product group (for example, whole grain, vegetables).
Furthermore, as the Choices Programme aims to promote appropriate energy intake, an energy criterion has been defined for product groups that either substantially contribute to energy intake (for example, main courses and filled sandwiches) or for which a limited consumption is recommended (discretionary product groups): for example, sugar-sweetened beverages (Popkin et al., 2006 (link)).
Publication 2011
A Fibers Beverages Carbohydrates Eating Fats Fibrosis Food Inulin Joints Micronutrient Intake Micronutrients Minerals Nutrient Intake Nutrients Phytochemicals Saturated Fatty Acid Sodium Sodium Chloride, Dietary Sugar-Sweetened Beverages Sugars Trans Fatty Acids Vegetables Vitamins Whole Grains

Most recents protocols related to «Inulin»

Example 1

NAME OF COMPONENTmg/sachet
Probiotic Material:
Lactobacillus helveticus150 billion CFU/g73.333
Rosell 52
Bifidobacterium longum 50 billion CFU/g20.000
R175
Lactobacillus plantarum150 billion CFU/g20.000
Rosell 1012
Carrier material:
Magnesium oxide41.446
Magnesium gluconate341.297
Potassium citrate138.290
Zinc gluconate111.111
Glutathione20.000
Lactoferrin11.364
Copper citrate2.834
Inulin500.000
Fructose1291.125
Additional (optional) excipients
Sucralose4.000
Acesulfame K12.000
Flavouring150.000
Aerosil 20040.000
Colouring: E1242.200
Colouring: E1021.000
Anhydrous citric acid220.000

The formulation described above is prepared as follows: Lactobacillus Plantarum, Lactobacillus helveticus, Bifidobacterium longum, are mixed with inulin and blended at 32 rpm for approximately 10 min. Thereafter, fructose, magnesium gluconate, zinc gluconate, citric acid, flavor, potassium citrate, magnesium oxide, silicon dioxide, glutathione, potassium acesulfame, lactoferrine, and sucralose are added to the mixture and blended at 32 rpm for another 10 min.

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Patent 2024
acesulfame potassium Aerosil Bifidobacterium longum Citric Acid Citric Acid, Anhydrous Copper Excipients Flavor Enhancers Fructose gluconate Glutathione Inulin Lactobacillus Lactobacillus helveticus Lactobacillus plantarum Lactoferrin Magnesium magnesium gluconate Minerals Oxide, Magnesium Oxides Potassium Citrate Prebiotics Probiotics Salts Silicon Dioxide sucralose zinc gluconate
Response surface methodology (RSM) was used to determine the effect of the three independent variables, that is, the addition amount of chaff dietary fiber(A), the addition amount of soybean hull dietary fiber (B), and the addition amount of inulin (C).
Seventeen treatments were conducted based on the Box-Behnken design (BBD). Each run was done in triplicate. The designed response surface tests are presented in Table 1.
According to the preliminary experiment based on RSM, the optimum condition of the three dietary fibers was determined and was used in the following experiments, which was 1.40% chaff dietary fiber, 1.42% soybean hull dietary fiber, and 3.24% inulin, respectively.
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Publication 2023
Dietary Fiber Inulin Soybeans
The MP was dissolved (0.6 mol/L NaCl,50 mmol/L NaH2SO4/Na2HSO4, pH 6.2) in the extract to adjust the protein concentration to 40 mg/mL. Different dietary fibers were added, respectively, homogenized at a low speed for 30 s by a homogenizer (FSH-2, Mengte, Changzhou, Jiangsu, China), and placed in a constant temperature water bath, which was gradually heated from room temperature to 75°C at a rate of 1°C/min and kept in the 75°C water bath for 10 min before being quickly removed and cooled in ice for 30 min, and finally stored overnight in a 4°C refrigerator for backup. All samples were equilibrated at room temperature for 30 min before testing.
According to the optimal proportion of the composite dietary fiber in the low-fat recombinant meat product obtained by the response surface method. Hull dietary fiber 1.40%, soybean hull dietary fiber 1.42%, inulin 3.24%, the experimental groups were divided into five groups: the control group (T0); added 6.06% chaff dietary fiber (T1); added 6.06% soybean hull dietary fiber (T2); added 6.06% inulin (T3); added 1.40% chaff dietary fiber +1.42% soybean hull dietary fiber +3.24 % inulin (T4).
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Publication 2023
Bath Dietary Fiber Fat-Restricted Diet Inulin Meat Products Proteins Sodium Chloride Soybeans
Fluorescein isothiocyanate (FITC)–inulin (150 mg) was dissolved in 0.9% NaCl (3 ml) at 75°C and dialyzed in 0.9% NaCl (1000 ml) at 25°C for 24 hours. Dialyzed FITC-inulin (3.74 μl/g body weight) was intravenously injected into living C57BL/6 mice at t = 8, 12, 16, 24, and 48 hours after treatment with CDDP-treated (20 mg/kg body weight) or saline-treated (0.2 ml) mice. Blood (approximately 20 μl) was collected via orbital at 3, 7, 10, 15, 35, 55, and 75 min after injection of FITC-inulin and then centrifuged for 20 min at 3500 rpm. The serum sample (10 μl) was diluted with Hepes buffer (40 μl, 500 mM, pH 7.4), and fluorescence was measured using a SpectraMax with excitation at 485 nm and emission at 538 nm. Serum fluorescence data were presented as a two-component exponential decay curve using nonlinear regression. GFR was calculated according to the equation: GFR = I/(A/α + B/β), where I is the amount of FITC-inulin delivered by the bolus injection, A and B are the y intercept values of the two decay rates, and α and β are the decay constants for the distribution and elimination phases, respectively.
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Publication 2023
Aftercare BLOOD Body Weight Buffers Cisplatin Fluorescein Fluorescence HEPES Inulin Isothiocyanates Mice, House Mice, Inbred C57BL Normal Saline Saline Solution Serum
To study the clearance of 14C-inulin from the rat brain, we consider 3 model variations.
We first assume that the bulk flow of fluid in the interstitial space is negligible and transport occurs only due to diffusion in the interstitial space. Hence, we use Eq (1). Clearance of 14C-inulin occurs at the brain surface and is modelled by appropriate boundary conditions described below. This scenario is represented by Test case 1 on Fig 1.
Secondly, we consider a clearance of 14C-inulin due to the glymphatic system. Hence, we use System (3) with |J| = 4 compartments: ECS, PVS around arteries, PVS around capillaries, and PVS around veins. Test case 2 in Fig 1 depicts this scenario. CSF is assumed to flow from the PVS around arteries to the PVS around capillaries or in the ECS. From the PVS around capillaries, CSF flows to the ECS or the PVS around veins. From the ECS, CSF may be reabsorbed in the PVS around veins or capillaries. Clearance from the brain may occur at the brain surface from the ECS, the PVS around veins and the PVS around arteries.
Thirdly, we add the effect of blood vasculature. Indeed, cerebral blood vessels are not impermeable, and some fluid could leak from them to the other structures [38 (link)]. This case is depicted by Test case 3 in Fig 1.
For the sake of clarity, in the following, we refer to these 3 applications of our modelling framework as
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Publication 2023
Arteries BLOOD Blood Vessel Brain Capillaries Dietary Fiber Diffusion Glymphatic System Inulin Veins

Top products related to «Inulin»

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Inulin is a type of carbohydrate that is commonly used in laboratory settings. It is a soluble dietary fiber that is extracted from various plant sources, such as chicory root. Inulin serves as a prebiotic, supporting the growth of beneficial gut bacteria.
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FITC-inulin is a fluorescein isothiocyanate (FITC) labeled inulin molecule. Inulin is a naturally occurring polysaccharide that is commonly used as a marker for glomerular filtration rate (GFR) measurement. The FITC label allows for the detection and quantification of inulin through fluorescence-based methods.
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Sucrose is a disaccharide composed of glucose and fructose. It is commonly used as a laboratory reagent for various applications, serving as a standard reference substance and control material in analytical procedures.
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Bovine serum albumin (BSA) is a common laboratory reagent derived from bovine blood plasma. It is a protein that serves as a stabilizer and blocking agent in various biochemical and immunological applications. BSA is widely used to maintain the activity and solubility of enzymes, proteins, and other biomolecules in experimental settings.
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Fructose is a type of monosaccharide sugar that is commonly used in laboratory settings. It is a naturally occurring carbohydrate found in fruits, honey, and certain vegetables. Fructose serves as a key component in various experimental and analytical procedures, particularly in the fields of biochemistry, food science, and nutrition research.
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Acetic acid is a colorless, vinegar-like liquid chemical compound. It is a commonly used laboratory reagent with the molecular formula CH3COOH. Acetic acid serves as a solvent, a pH adjuster, and a reactant in various chemical processes.
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D-glucose is a type of monosaccharide, a simple sugar that serves as the primary source of energy for many organisms. It is a colorless, crystalline solid that is soluble in water and other polar solvents. D-glucose is a naturally occurring compound and is a key component of various biological processes.
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Gallic acid is a naturally occurring organic compound that can be used as a laboratory reagent. It is a white to light tan crystalline solid with the chemical formula C6H2(OH)3COOH. Gallic acid is commonly used in various analytical and research applications.
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α-amylase is an enzyme commonly used in laboratory settings. It functions by catalyzing the hydrolysis of starch, glycogen, and related polysaccharides into smaller carbohydrate units such as maltose and glucose.
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Sodium hydroxide is a chemical compound with the formula NaOH. It is a white, odorless, crystalline solid that is highly soluble in water and is a strong base. It is commonly used in various laboratory applications as a reagent.

More about "Inulin"

Inulin is a versatile and fascinating polysaccharide found in many plants, particularly in the roots and tubers of certain species.
This soluble dietary fiber is known for its prebiotic properties, meaning it stimulates the growth of beneficial gut bacteria.
Researchers have been studying inulin extensively for its potential health benefits, including improved digestion, enhanced immune function, and reduced risk of chronic conditions like diabetes and obesity.
Inulin is closely related to other carbohydrates like sucrose, fructose, and D-glucose, and it can be modified through processes like hydrolysis, acetylation, and enzymatic reactions to create a variety of useful derivatives.
FITC-inulin, for example, is a fluorescently labeled form of inulin that is often used in research to track and quantify its movement and absorption in the body.
Beyond its nutritional and therapeutic applications, inulin has also been explored for its potential use in food processing and formulation.
Its ability to enhance texture, stability, and mouthfeel in various products has made it a valuable ingredient for food manufacturers.
The future of inulin research is particularly exciting, with scientists continuing to explore novel ways to harness its unique properties.
From developing new extraction and purification methods to investigating its synergistic effects with other compounds, the potential of this remarkable polysaccharide is yet to be fully realized.
Experienve the future of inulin research today!