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Sutures

Sutures are medical devices used to close and repair wounds, incisions, and surgical procedures.
They consist of threads or filaments, natural or synthetic, that are used to stitch together tissue.
Sutures play a crucial role in wound management, promoting healing and minimizing the risk of infection or complications.
Researchers and clinicinas must carefully select the most effective suture techniques to optimize patient outcomes.
PubComapre.ai is an AI-powered platform that helps locate the best suture protocols from the literature, preprints, and patents, ensuring reproducibility and research accuracy.

Most cited protocols related to «Sutures»

Sparse Labeling of Cortical Neurons for Imaging

Constructs used to produce AAV included pGP-AAV-syn-GCaMP-WPRE and the Cre recombinase-activated construct pGP-AAV-syn-flex-GCaMP-WPRE. Virus was injected slowly (30 nL in 5 minutes) at a depth of 250 μm into the primary visual cortex (two sites, 2.5 and 2.9 mm lateral from the lambda suture). For population imaging and electrophysiology (Fig 2-3), AAV2/1-syn-GCaMP-WPRE virus (titer: ∼10^{11 (link)} -10^{12 (link)} genomes/mL) was injected into the visual cortex of C57BL/6J mice (1.5-2 months old)^{6 (link)}. For dendritic imaging (Fig 4, 5 and 6a-f), sparse labeling was achieved by injecting a mixture of diluted AAV2/1-syn-Cre particles (titer: ∼10^{12 (link)} genomes/mL, diluted 8000-20,000 fold in PBS) and high titer, Cre-dependent GCaMP6s virus (∼8×10^{11 (link)} genomes/mL). This produces strong GCaMP6 expression in a small subset of neurons (∼3-5 cells in a 250 μm × 250 μm × 250 μm volume), defined by Cre expression^{56 (link)}. Both pyramidal (Fig. 4-5) and GABAergic (Fig. 6) neurons were labeled using this approach, but they could be distinguished based on the presence or absence of dendritic spines. Post hoc immunolabeling further identified the imaged cells. For specific labeling of parvalbumin interneurons (Fig. 6g and Supplementary Fig. 12), Cre-dependent GCaMP6s AAV was injected into the visual cortex of PV-IRES-Cre mice^{57 (link)}. Individual somata (Supplementary Fig. 12) and dendritic segments could be recognized (Fig. 6 g, h, total length of imaged dendrite: 2.86 mm), but the high labeling density made it difficult to track individual dendrites over long distances.

Chen T.W., Wardill T.J., Sun Y., Pulver S.R., Renninger S.L., Baohan A., Schreiter E.R., Kerr R.A., Orger M.B., Jayaraman V., Looger L.L., Svoboda K, & Kim D.S. (2013). Ultra-sensitive fluorescent proteins for imaging neuronal activity. Nature, 499(7458), 295-300.

Publication 2013

Cells Cre recombinase Dendrites Dendritic Spines Genome Internal Ribosome Entry Sites Interneurons Mice, Inbred C57BL Neurons Parvalbumins Striate Cortex Sutures TCL1B protein, human Virus Visual Cortex

Cranial Window Implantation for Chronic Imaging in Mice

After 2-4 weeks of expression, mice were anesthetized using isoflurane (3% for induction, 1.5-2% during surgery) and a circular craniotomy (2-3 mm diameter) was made above V1 (centered 2.7 mm lateral from the lambda suture). For acute experiments, the craniotomy was covered with agarose (1-1.3 %), and a round glass coverslip (Warner Instruments; 5mm diameter; #1 thickness) was cemented to the skull to reduce motion of the exposed brain. A custom titanium head post was fixed to the skull using black dental cement (Contemporary Ortho-Jet). For simultaneous imaging and cell-attached recording, the exposed brain was covered with ∼1 mm thick agarose (1.3%) without a coverslip. For chronic imaging experiments, the imaging window was constructed from two layers of microscope coverglass^{6 (link)}. A larger piece (Fisher, #1 thickness) was attached to the bone and a smaller insert (#2 thickness) was fitted snugly into the craniotomy. Imaging experiments were started ∼1-2 weeks after chronic window implantation.

Publication 2013

Bones Brain Cells Craniotomy Cranium Dental Cements Head Isoflurane Microscopy Mus Operative Surgical Procedures Ovum Implantation Sepharose Sutures Titanium

Standardized Venation Terminology for Planthoppers

As elytra is used in Coleoptera, we used the term ‘tegmina’ (singular: tegmen) as a synonym to mention the more or less sclerified mesothoracic forewings, a convention in most of Hemiptera; they are usually covering the membranous metathoracic hind wings at repose.
The general venation schema for planthoppers is here provided based on a fulgoromorphan ground plan slightly modified from the one proposed by Shcherbakov (1996 ). Terminology is completed according to Bourgoin (1997 ) who recommended the use of areas (nodal cells, major vein areas) for the interpretation of veins and updated from Bourgoin and Szwedo (2008 ) and Szwedo and Żyła (2009 ), including the recent proposal of the CuA zigzag vein (=arculus auctorum, Emeljanov 1987 ) as autapomorphic for Paraneoptera (Nel et al. 2012 (link)).
The standardized terminology proposed is built upon the various major vein nomenclature systems used and upon homology-driven morphological interpretations concerning both extant and extinct taxa samples according to all major authors in these topics (Metcalf 1913 (link); Muir 1913 , 1923 ; Melichar 1923 ; Fennah 1944 ; Hamilton 1972 ; Emeljanov 1977 , 1987 ; Shcherbakov 1981 , 1996 ; Zelazny 1981 ; Kukalová-Peck 1983 (link); Chou et al. 1985 ; Anufriev and Emeljanov 1988 ; Dworakowska 1988 ; Bourgoin 1997 ; Zelazny and Webb 2011 ; Ding 2006 ; Nel et al. 2012 (link), 2013 (link); Gnezdilov 2013 (link)).
A corresponding terminology between these major systems is proposed (Table 1), and a definition is provided for each structure.Table 1

Corresponding terminologies between main vein system interpretations since Metcalf (1913 (link)), with the recommended standardized one (in bold)

Metcalf (1913 (link))

Sc + R + M

Sc + R

Sc (two branches)

M (typically 4 branched)

A3 s branch

Melichar (1923 )

Costal vein

Subcostal vein

Radius 1

Radius 2

Median vein

Cubitus

Clavus suture

Claval vein external branch

Claval vein internal branch

Scutellar + clavus sutural margins

Fennah (1944 )

Sc + R + M

Sc + R

R1, Rs

Cu1

Cu2

Pcu

Hamilton (1972 )

S + M

M (forks first in MA and MP)

P + E

Margin

Emeljanov (1977 )

S + M

Sc + R

R₁Sc + R₂

R₃

CuA

CuP

Pcu

Shcherbakov (1981 )

Sc + R + M

(Sc +) R

R₁

R₁a

CuA

CuP

Pcu

Chou et al. (1985 )

R + M

Clavus suture

Margin

Dworakowska (1988 )

Pc + CP

ScP + R + M

ScP + R + MA

ScP + RA

RP + MA

CuA

CuP

AP’

AP”

Ding (2006 )

Sc + R + M

Sc + R

Sc2

R₁

M (‘Rs, M₁, M₂, M₃′ = M₁, M₂, M₃, M₄)

Cu1 (‘Cu1a’ = CuA₁)

Cu2

IIA

Margin

Interpretation and recommended terminology

Pc + CP

ScP + R + M + CuA

ScP + R

ScP + RA

RP (+MA)

CuA (forks in CuA₁ and CuA₂)

CuP

Pcu

Bourgoin T., Wang R.R., Asche M., Hoch H., Soulier-Perkins A., Stroiński A., Yap S, & Szwedo J. (2014). From micropterism to hyperpterism: recognition strategy and standardized homology-driven terminology of the forewing venation patterns in planthoppers (Hemiptera: Fulgoromorpha). Zoomorphology, 134(1), 63-77.

Publication 2014

Beetles Cells Conferences Corns Extinction, Psychological Hemiptera Maritally Unattached Ribs Sutures Tegmentum Mesencephali Tissue, Membrane Veins

Murine Ischemia-Reperfusion Injury Protocol

This I/R injury procedure in mice is essentially the same as the procedure for inducing MI except that a slipknot is tied around the LCA 2-3 mm from its origin with a 6-0 silk suture as shown in Fig. 2A. The heart is then quickly placed back into the thoracic space followed by manual evacuation of air and the skin closing (Fig. 2B). The internal needle end of slipknot suture is cut as short as possible and the other end of the suture is approximately 0.8 cm long and remains outside of the chest (Fig. 2C). After 30 min of ischemia, the slipknot is released by pulling the long end of slipknot suture smoothly and gently until a feeling of release is sensed at which time the myocardium begins reperfusing. This outside-the-skin suture knot releasing method should only be attempted by the experienced surgeon. Alternatively, the mouse can be re-anesthetized with 2% isoflurane inhalation, the chest reopened, and the slipknot released by pulling the long end of slipknot suture smoothly and gently, and then following manual evacuation of the pneumothorax and chest closure. As above for the MI model, ventilation is recommended until times are fast enough to do this procedure without ventilation.

Gao E., Lei Y.H., Shang X., Huang Z.M., Zuo L., Boucher M., Fan Q., Chuprun J.K., Ma X.L, & Koch W.J. (2010). A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse. Circulation research, 107(12), 1445-1453.

Publication 2010

Chest Heart Inhalation Injuries Ischemia Isoflurane Mice, Laboratory Myocardium Needles Pneumothorax Silk Skin Surgeons Sutures

Comprehensive Analysis of Surgical Complications at a University Hospital

Over the 6‑month period covering April 2010 to September 2010, all patients admitted to one of our patient wards at the Division of General Surgery, Department of Surgery, Medical University of Vienna were included in this study.
The Division of General Surgery in our university hospital consists of the following teams and specializations: colorectal surgery, hepatobiliary surgery, endocrine surgery, upper gastrointestinal (GI) surgery (esophageal and stomach surgery), bariatric surgery, breast surgery, and pancreatic surgery.
The patient data were extracted by reviewing all discharge letters from that period taken from the digital archives.
Overall, 517 patients were admitted over this period, some repeatedly, leading to a total of 817 admissions. These 517 patients underwent 463 operations. The complications of these operations were then rated according to the Clavien-Dindo classification (Table 1). For easier use, the suffix “d” for permanent disability was not drawn upon.Table 1

Clavien-Dindo classification

Grade	Definition
Grade I	Any deviation from the normal postoperative course without the need for pharmacological treatment, or surgical, endoscopic, and radiological interventions.Allowed therapeutic regimens are: drugs as antiemetics, antipyretics, analgetics, diuretics and electrolytes, and physiotherapy. This grade also includes wound infections opened at the bedside
Grade II	Requiring pharmacological treatment with drugs other than such allowed for grade I complications.Blood transfusions and total parenteral nutrition are also included
Grade III	Requiring surgical, endoscopic, or radiological intervention
Grade IIIa	Intervention not under general anesthesia
Grade IIIb	Intervention under general anesthesia
Grade IV	Life-threatening complication (including central nervous system complications) requiring IC/ICU management
Grade IVa	Single organ dysfunction (including dialysis)
Grade IVb	Multiorgan dysfunction
Grade V	Death of a patient

According to Dindo et al. [6 (link)]

IC intermediate care, ICU intensive care unit

The operations were sorted according to the complexity ranking (eight groups) in the accounting system of the Austrian Chamber of Physicians (Table 2; [8 ]).Table 2

Operation groups (complexity according to the Austrian Chamber of Physicians)

Operation group	Examples
I	Abscess incisions, secondary sutures, proctoscopy, skin biopsy
II	Excisions of atheromas, fibromas, lipomas, incisions of anal abscesses
III	Toe amputation, small lymph node extirpation, thoracic drainage, colonoscopy
IV	Tracheotomy, appendectomy, hernia operation, colostomy, gastrostomy, ERCP
V	Gastroenterostomy, interventions for recurrent hernia, Cimino fistula, radical varicose vein stripping
VI	Strumectomy, cholecystectomy, splenectomy, hemicolectomy, reduction mammoplasty
VII	Partial pancreatectomy, subtotal colectomy, subsegmental and large liver resections
VIII	Esophageal resection, open surgery of aortic aneurysms, organ transplantation

Bolliger M., Kroehnert J.A., Molineus F., Kandioler D., Schindl M, & Riss P. (2018). Experiences with the standardized classification of surgical complications (Clavien-Dindo) in general surgery patients. European Surgery, 50(6), 256-261.

Publication 2018

Amputation Antiemetics Antipyretics Anus Aortic Aneurysm Appendectomy Atheroma Bariatric Surgery Blood Transfusion Central Nervous System Cholecystectomy Colectomy Colostomy Dialysis Disabled Persons Diuretics Drainage Electrolytes Endocrine Surgical Procedures Fibroma Fingers Fistula Gastrointestinal Surgical Procedure Gastrostomy Hemicolectomy Hepatectomy Hernia Intensive Care Lipoma Lymph Node Excision Operative Surgical Procedures Organ Transplantation Pancreas Pancreatectomy Parenteral Nutrition, Total Patient Discharge Patients Pharmaceutical Preparations Pharmacotherapy Physicians Proctoscopy Skin Splenectomy Stomach Surgical Endoscopy Surgical Wound Sutures Therapeutics Therapy, Physical Thoracic Surgical Procedures Treatment Protocols Upper Gastrointestinal Tract Varices Wound Infection X-Rays, Diagnostic

Most recents protocols related to «Sutures»

Secure Medical Device Fixation

Not available on PMC !

Example 4

In operation, the medical device (1) may be tethered to the surrounding tissue, such as connective tissue or muscle to prevent an undesired shifting of the medical device (1). A suture (56) may be attached to the balloon (5) and the membrane-covered port (55) or to a projecting tab (57) and tied to the surrounding tissue.

US11864952B2. Tissue expander (2024-01-09). None [US]. Inventors: Hakim Said [US].

Patent 2024

Connective Tissue Medical Devices Muscle Tissue Sutures Tissue, Membrane Tissue Expansion Devices Tissues

Chitosan Biomaterial Characterization

Not available on PMC !

Example 6

FIG. 13 shows the in vitro degradation of the acetyl-chitosan, butyryl-chitosan and Na₂CO₃treated chitosan film when exposed to 100 μg/ml of lysosome in phosphate buffered saline (PBS). Both acetyl-chitosan and butyryl-chitosan resisted degradation and maintained mass longer than Na₂CO₃treated chitosan film.

FIG. 14 shows the ultimate suture pullout load for acetyl-chitosan, butyryl-chitosan and regenerated (deacylated) chitosan when wet or dry.

FIG. 15 shows the weight gain or swelling after exposure to a hydrophilic solvent of Na₂CO₃treated chitosan film, acetyl-chitosan, butyryl-chitosan and regenerated (deacylated) chitosan. The stabilized electrospun chitosan fiber membranes show good cytocompatibility, structural stability, suggesting future exploration in tissue engineering applications.

US11878088B2. Chitosan nanofiber compositions, compositions comprising modified chitosan, and methods of use (2024-01-23). The University of Memphis Research Foundation [US]. Inventors: Joel D. Bumgardner [US], Hengjie Su [US], Tomoko Fujiwara [US], Daniel G. Abebe [US], Kwei-Yu Liu [US].

Patent 2024

Chitosan Fibrosis Lysosomes Phosphates Saline Solution Solvents Sutures Tissue, Membrane

Chitosan-based Biomaterials Characterization

Not available on PMC !

Example 10

FIG. 25 shows the ultimate suture pullout load for acetyl-chitosan, butyryl-chitosan, chitosan powder and Na₂CO₃chitosan when wet or dry.

FIG. 26 shows the weight gain or swelling after exposure to a hydrophilic solvent of chitosan power, acetyl-chitosan, butyryl-chitosan, regenerated (deacylated) chitosan and Na₂CO₃treated chitosan. The butyryl-chitosan and the regenerated electrospun chitosan nanofibers show good cytocompatibility, structural stability, suggesting future exploration in tissue engineering applications.

FIG. 27 shows x-ray diffraction of chitosan power, Na₂CO₃treated chitosan fibers, as-spun chitosan and acetyl-chitosan.

Patent 2024

Chitosan Powder Solvents Sutures X-Ray Diffraction

Mechanical Bowel Preparation and Anastomotic Techniques

We routinely performed mechanical bowel preparation 1 day before surgery regardless of anastomotic technique. In the ECA group, the mobilized bowel was extracted through a commercial wound protector following a further incision that continued through the previous periumbilical incision (Fig. 1A). An ECA was performed in an end-to-side manner using a circular stapler, side-to-side using a linear stapler or end-to-end with hand-sewn technique. In the ICA group, the transverse mesocolon and small bowel mesentery were divided using a surgical energy device. Subsequently, the transverse colon and terminal ileum were transected using laparoscopic staplers (Fig. 1B). We placed gauze under the anastomotic site to minimize the spread of bowel content into the abdominal cavity during the ICA. Enterotomy and colostomy were performed, and a linear stapler was used to create an isoperistaltic, side-to-side anastomosis. After stapling for anastomosis, sufficient irrigation and suction were performed. The stapler insertion site was closed with continuous stitches using V-Loc sutures (Covidien). The specimen was extracted through a periumbilical or Pfannenstiel incision.

Kim S., Bae S.U., Jeong W.K., Baek S.K, & Son Y.G. (2023). Effect of intracorporeal anastomosis on postoperative ileus after laparoscopic right colectomy. Annals of Surgical Treatment and Research, 104(3), 156-163.

Publication 2023

Abdominal Cavity Colostomy Ileum Intestinal Contents Intestines Intestines, Small Laparoscopy Medical Devices Mesentery Mesocolon Operative Surgical Procedures Suction Drainage Surgery, Day Surgical Anastomoses Sutures Transverse Colon Wounds

Comparison of Absorbable Skin Stapling vs Handstitching for Mastectomy Skin Closure

There was no difference in surgical procedure between the ASS group and HS group except for skin closure. For the ASS group, we used Insorb (Incisive Surgical, Inc.), which is a brand name of absorbable subcuticular skin stapler. First, the operator grasps both edges of the skin together with a tooth forceps using 1 hand, while the other hand holds the stapler. After locating the nose of the stapler underneath the grasped tissue, the operator fires the staple. This process is repeated along the incision till the opposite end, and staples are placed at about 7-mm intervals. Fig. 2 shows a mastectomy field from our center in which an ASS was being applied. For the HS group, interrupted subcuticular suture was done using Monosyn (B. Braun). First-generation cephalosporin was injected once on the day of the operation as a prophylactic antibiotic into every patient, and no additional antibiotics were used postoperatively. Only for the patients in whom SSI was detected was an additional third-generation cephalosporin plus metronidazole used empirically; or in cases of positive culture from the wound, other proper antibiotics were administered according to the result of the culture.

Lee J., Lee J.E., Ryu J.M., Kim S.W., Nam S.J, & Yu J.H. (2023). The use of absorbable skin stapler in mastectomy does not increase the rate of surgical site infection. Annals of Surgical Treatment and Research, 104(3), 137-143.

Publication 2023

Antibiotics Antibiotics, Antitubercular Cephalosporins Condoms Fires Forceps Mastectomy Metronidazole Nose Operative Surgical Procedures Patients Skin Staple, Surgical Surgery, Day Sutures Tissues Tooth Wounds

Top products related to «Sutures»

Rompun by Bayer

Sourced in Germany, France, United States, United Kingdom, Canada, Italy, Brazil, Belgium, Cameroon, Switzerland, Spain, Australia, Ireland, Sweden, Portugal, Netherlands, Austria, Denmark, New Zealand

Rompun is a veterinary drug used as a sedative and analgesic for animals. It contains the active ingredient xylazine hydrochloride. Rompun is designed to induce a state of sedation and pain relief in animals during medical procedures or transportation.

Vicryl by Johnson & Johnson

Sourced in United States, Germany, Brazil, France, Australia, Italy

Vicryl is a sterile, absorbable surgical suture material composed of a copolymer of glycolic acid and lactic acid. It is designed for use in general soft tissue approximation and/or ligation, including use in ophthalmic procedures.

Pentobarbital sodium by Merck Group

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Pentobarbital sodium is a laboratory chemical compound. It is a barbiturate drug that acts as a central nervous system depressant. Pentobarbital sodium is commonly used in research and scientific applications.

Prolene by Johnson & Johnson

Sourced in United States, Germany

Prolene is a surgical suture material manufactured by Johnson & Johnson. It is a monofilament, nonabsorbable suture made of polypropylene. Prolene is designed for use in general soft tissue approximation and/or ligation, including use in cardiovascular, ophthalmic, and neurological procedures.

Ethilon by Johnson & Johnson

Sourced in United States, Germany, United Kingdom

Ethilon is a monofilament suture material manufactured by Johnson & Johnson. It is made from nylon and is designed for use in general soft tissue approximation and/or ligation.

Isoflurane by Abbott

Sourced in United States, United Kingdom, Germany, Japan, Switzerland, Canada, Israel, Sweden, China, France, Brazil, Australia, Cameroon, Spain, Belgium

Isoflurane is an inhaled anesthetic agent used to induce and maintain general anesthesia in medical and veterinary settings. It is a clear, colorless, and volatile liquid. Isoflurane functions as a potent and effective anesthetic by depressing the central nervous system, resulting in unconsciousness, analgesia, and muscle relaxation.

C57bl 6j mice by Jackson ImmunoResearch

Sourced in United States, Montenegro, Japan, Canada, United Kingdom, Germany, Macao, Switzerland, China

C57BL/6J mice are a widely used inbred mouse strain. They are a commonly used model organism in biomedical research.

Stereotaxic frame by Kopf Instruments

Sourced in United States, Germany, Italy

The Stereotaxic frame is a laboratory instrument used to immobilize and position the head of a subject, typically an animal, during surgical or experimental procedures. It provides a secure and reproducible method for aligning the subject's head in a three-dimensional coordinate system to enable precise targeting of specific brain regions.

Xylazine by Bayer

Sourced in Germany, France, Japan, United States, Brazil, Spain, Canada, Switzerland, Cameroon, Australia, United Kingdom

Xylazine is a pharmaceutical product used as a sedative and analgesic in veterinary medicine. It is a central alpha-2 adrenergic agonist that produces a calming effect and pain relief in animals. Xylazine is used to facilitate handling, examination, and minor surgical procedures in various animal species.

Zoletil by Virbac

Sourced in France, United States, Italy, Australia, Germany, China, Thailand, Cameroon, United Kingdom, Netherlands, New Zealand

Zoletil is a general anesthetic and analgesic used in veterinary medicine. It is a combination of two active compounds, tiletamine and zolazepam, that work together to induce a state of deep sedation and pain relief in animals. The product is administered by injection and is commonly used for a variety of veterinary procedures, including surgery, diagnostic imaging, and minor treatments. Zoletil is intended for use under the supervision of licensed veterinary professionals.

What are the main types of sutures available?

Sutures come in a variety of materials, including natural fibers like silk or catgut, as well as synthetic materials like nylon, polypropylene, and polyester. Each type has unique properties that make them suitable for different applications. For example, absorbable sutures like catgut are ideal for internal wound closure, while non-absorbable sutures like nylon are better for external wounds. Researchers and clinicians must carefully select the right suture type to optimize patient outcomes.

How can I ensure I'm using the most effective suture technique for my research?

PubCompare.ai can help you identify the optimal suture protocols for your specific research goals. The platform's AI-powered analysis can screen the literature, preprints, and patents to pinpoint critical insights on suture effectiveness. By leveraging PubCompare.ai, you can more efficiently compare suture techniques and choose the best option to ensure reproducibility and accuracy in your research.

What are some common challenges with using sutures?

Some common challenges with using sutures include the risk of infection, tissue damage, and improper wound healing. Factors like suture material, tensile strength, and knot security can all impact the success of a suture procedure. Researchers must be diligent in selecting the right suture type and technique to minimize these risks and optimize patient outcomes. PubCompare.ai can help you navigte these challeges by providing data-driven insights on the most effective suture protocols.

How can PubCompare.ai help me find the best suture protocols for my research?

PubCompare.ai allows you to more efficiently screen the literature on suture protocols and leverage AI to pinpoint critical insights. The platform's intelligent comparisons can help you identify the most effective suture techniques for your specific research goals, enabling you to choose the best option for reproducibility and accuracy. By using PubCompare.ai, you can unleash the full potential of your research on sutures and ensure you're using the most optimal protocols.

Sutures

Most cited protocols related to «Sutures»

Most recents protocols related to «Sutures»

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