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Transducers, Pressure

Transducers, Pressure: Devices that convert the energy of pressure or force into electrical energy.
They are used to measure pressure in fluids, solids, and gases, and find application in a wide range of scientific and engineering disciplines.
Pressure transducers often utilize piezoelectric, resistive, or capacitive elements to generate an electric signal proportional to the applied pressure.
Accurate measurement and comparison of pressure transducer performance is cricitcal for experimental reproducibility and optimization.

Most cited protocols related to «Transducers, Pressure»

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Publication 2013
Epistropheus Medical Devices Muscle Tissue Reading Frames Sus scrofa Tissues Transducers Transducers, Pressure Ultrasonics
After set duration of hypoxic or normoxic exposure, mice were weighed and anesthetized with Avertin (tribromoethanol) 0.375 mg/g body weight injected intraperitoneally. A tracheostomy was performed with a 22 gauge angiocatheter and secured in place with a 4.0 silk suture. Mice were ventilated with a Harvard Mini-Vent with a stroke volume of 325 µl and rate of 150 stroke/min. Anesthesia was maintained throughout with 1% isoflurane mixed with room air or 10% O2. After thoracotomy, a 25 gauge needle fitted to a pressure transducer was inserted into the right ventricle. Right ventricular systolic pressure (RVSP) was measured and continuously recorded on a Gould polygraph (model TA-400, Gould instruments, Cleveland, Ohio). Immediately after RVSP measurements were obtained, the mice were sacrificed.
An expanded Materials and Methods section is available in the online data supplement at http://circres.ahajournals.org and provides details of all materials, bone marrow transplantation, pulmonary vascular morphometry, Western blot, immunohistochemistry, immunofluorescence and statistical analyses.
Publication 2009
Anesthesia Blood Vessel Body Weight Bone Marrow Transplantation Cerebrovascular Accident Dietary Supplements Hypoxia Immunofluorescence Immunohistochemistry Isoflurane Lung Mus Needles Silk Stroke Volume Sutures Systolic Pressure Thoracotomy Tracheostomy Transducers, Pressure tribromoethanol Ventricles, Right Western Blot
Left ventricular pressure was measured by a micromanometer-tipped catheter (Millar) and a fluid-filled catheter connected to an external pressure transducer served as an absolute pressure reference. Brachial artery cuff pressure was measured. Myocardial strain was measured by STE in apical long-axis and two- and four-chamber views (frame rate 67 ± 7s−1), and 2D images with a narrow sector over the valves (frame rate 91 ± 23 s−1) were used to define opening and closure of the aortic and mitral valves. Pressure and strain data were recorded in a synchronized fashion and stored on the scanner for offline analysis. Echocardiography was performed immediately after the PET study. Patients with echocardiography images not amenable for speckle tracking were excluded prior to invasive pressure measurements (n = 2). An average of 16 ± 2 segments were analysed in each patient.
Publication 2012
Aorta Brachial Artery Catheters Echocardiography Epistropheus Left Ventricles Mitral Valve Myocardium Patients Pressure Reading Frames Strains Transducers, Pressure
Airway responsiveness was assessed as a change in airway function after challenge with aerosolized methacholine (MCh) via the airways. Anesthetized, tracheostomized mice were mechanically ventilated and lung function was assessed using methods similar to those described by Martin et al. (8 (link)). A four-way connector was attached to the tracheostomy tube, with two ports connected to the inspiratory and expiratory sides of a ventilator (model 683; Harvard Apparatus, South Natick, MA). Ventilation was achieved at 160 breaths/min and a tidal volume of 0.15 ml with a positive end–expiratory pressure of 2–4 cm H2O.
The Plexiglas chamber containing the mouse was continuous with a 1.0-liter glass bottle filled with copper gauze to stabilize the volume signal for thermal drift. Transpulmonary pressure was detected by a pressure transducer with one side connected to the fourth port of the four-way connector and the other side connected to a second port on the plethysmograph. Changes in lung volume were measured by detecting pressure changes in the plethysmographic chamber through a port in the connecting tube with a pressure transducer and then referenced to a second copper gauze–filled 1.0-liter glass bottle. Flow was measured by digital differentiation of the volume signal. Lung resistance (Rl) and dynamic compliance (Cdyn) were continuously computed (Labview, National Instruments, TX) by fitting flow, volume, and pressure to an equation of motion.
Aerosolized agents were administered for 10 s with a tidal volume of 0.5 ml (9 (link)). From 20 s up to 3 min after each aerosol challenge, the data of Rl and Cdyn were continuously collected. Maximum values of Rl and minimum values of Cdyn were taken to express changes in murine airway function.
Publication 1997
Copper Exhaling Fingers Inhalation Lung Lung Volumes Mus Plethysmography Plexiglas Positive End-Expiratory Pressure Pressure Respiratory Physiology Tidal Volume Tracheostomy Transducers, Pressure
RH-PAT (Itamar) is a recently validated noninvasive method of assessing endothelial function. RH-PAT correlates with the more labor-intensive flow-mediated dilatation method (57 (link)) and endothelial function in other vascular beds (57 (link)). At least 50% of RH is dependent on endothelial NO production (24 (link)). Finger probes measure digital volume changes detected by a pressure transducer. PAT was measured before and after a 5-min ischemic stress, generating an RH-PAT index, normalized to the control arm (57 (link)). All studies were performed in a quiet air-conditioned room at 25°C after a 20-min equilibration time. In 10 patients with SM, tests were performed in a high dependency unit at similar temperatures. To internally validate endothelial function measurements, RH-PAT indices were repeated 0.5–0.75 h after initial measurements in 37 HC. The reproducibility coefficient was 0.59 (58 (link)), comparable with previous results (59 (link)) and those obtained with the flow-mediated dilatation method (51 (link)).
Publication 2007
Dilatation Endothelium Endothelium, Vascular Fingers Obstetric Labor Patients Transducers, Pressure

Most recents protocols related to «Transducers, Pressure»

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Example 6

ICP is monitored using a Samba 420 Sensor, pressure transducer, with a Samba 202 control unit (Harvard Apparatus, Holliston, MA). This ICP monitoring system consists of a 0.42 mm silicon sensor element mounted on an optical fiber. A 20-gauge syringe needle is implanted through the cisterna magna to a depth of ˜1 cm. The needle then acts as a guide for insertion of the Samba Sensor and the site of implantation and the open end of the needle are sealed with 100% silicone sealant. A baseline ICP reading is established followed by a water bolus IP injection (20% weight of animal) with or without Compound 1. ICP is monitored until the animal expires from the water load.

Adjusting for the slight rise in ICP observed in the animals when they are monitored without the water bolus injection (FIG. 9, No Water Toxicity), Compound 1 at 0.76 mg/kg reduces the relative rate of ICP rise by 36%, from 3.6×10−3 min−1 to 2.3×10−3 min−1 (n=6 mice/treatment, mean±SEM).

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Patent 2024
Acceptance and Commitment Therapy Animals Injections, Intraperitoneal Intracranial Pressure Magna, Cisterna Mice, Laboratory Needles Ovum Implantation Silicon Silicones Syringes Transducers, Pressure

Example 3

Preparations of full-thickness colonic segments (˜1.5 cm) were allowed to equilibrate in 37° C. Kreb's-jacketed organ baths with their distal ends opening to a pressure transducer and maintained under basal pressure of 5-cm column of vehicle (RL). The proximal end was closed during pressure recordings but opened to allow luminal infusion of vehicle or tryptamine in solution (100 μM, 1 mM and 3 mM; 10 minutes per treatment; n=5-7 mice).

Contractile frequency was not significantly different comparing tryptamine treatments with vehicle controls; however, there was a trend toward increased frequency in segments treated with luminal 1 mM tryptamine compared to controls (5.9±0.8 vs 4.1±0.6; P=0.15). Mean contractile amplitude and contractile magnitude, as measured by area under the curve, were also not significantly different between control (vehicle alone) and any of the tryptamine concentrations examined. Contractile duration, measured at half amplitude, was not significantly different between vehicle controls and any of the luminal tryptamine treatments.

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Patent 2024
Bath Colon Mus Muscle Contraction Phenobarbital Pressure Transducers, Pressure Tryptamines
Animals were anesthetized with 3–4% isoflurane and placed on controlled heating pads. Right ventricular systolic pressure (RVSP) was measured by advancing a 2F curve tip pressure transducer catheter (SPR-513, Millar Instruments) into the right ventricle (RV) via the right jugular vein under 1.5–2% isoflurane anesthesia. En-bloc heart and lungs were collected, and lungs were perfused with physiological saline via the right ventricular outflow tract to flush blood cells from the pulmonary circulation. RV hypertrophy was assessed by calculating Fulton’s index, the weight ratio of the RV free wall to the combined left ventricle (LV) + septum [RV/(LV + S)].
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Publication 2023
Anesthesia Animals Blood Cells Catheters Flushing Heart Block Isoflurane Jugular Vein Left Ventricles Lung physiology Pulmonary Circulation Right Ventricular Hypertrophy Saline Solution Systolic Pressure Transducers, Pressure Ventricles, Right Ventricular Septum
A closed-loop circulatory flow system was designed that included a centrifugal pump (Cole-Parmer, IL, United States), reservoir, flow meter and ultrasonic flow probes, and pressure transducers as shown in Figures 1A,B. The flow loop was connected to the cerebrovascular model, which was placed in the supine orientation. The inlet and outlet flow rates and pressures were monitored using ultrasonic flow probes (Transonic Systems, Inc., Millis, MA) and pressure transducers (Merit Medical, South Jordan, UT), respectively. The pressure transducers were connected to an analog data acquisition module (DAQ, National Instruments, Texas, United States) and recorded using LabVIEW software (National Instruments, Texas, United States).
Similar to Riley et al. (26 (link)), the working fluid consisted of a mixture of water (60% by weight) and glycerol (40% by weight) to obtain a density and dynamic viscosity that is representative of blood (1.09 ± 0.03 g/ml and 3.98 ± 0.14 cP, respectively) at an operating temperature of 22.2°C. Experiments were performed using a steady inlet flow rate of 5.17 ± 0.078 L/min, corresponding to a Reynolds number (Re) in the inlet tube of approximately 3890. This inlet flow rate was chosen to correspond to a representative mean physiological cardiac output of an adult. An extended tube of 900 mm in length was attached to the model inlet such that the flow entering the model inlet was fully developed. To study the effect of a stroke condition on the mean arterial pressure and flow rate in the cerebral arteries, nylon spherical clots of three different sizes (3.15 mm, 4.75 mm, and 6.38 mm in diameter) were manually inserted into the right MCA (RMCA) to completely block the vessel and the corresponding flow through outlet 4, as depicted in Figure 1C.
Three separate experiments were performed for both conditions (normal and stroke) to measure the flow rate and pressure at the inlet and various outlets in order to provide boundary conditions for the CFD simulations and for validation. Because the fluid heats up as it is continuously pumped through the flow loop, we waited for 30 min to allow for the fluid temperature to reach a steady state (22.2°C) before measuring the flow rate and pressure. Importantly, the viscosity of the fluid was tuned to account for the effect of this temperature rise, so as to obtain the desired value of 3.98 cP at the steady-state operating temperature. The regional distribution of the flow rate was tuned to match available literature data (30 (link), 31 (link)) by adjusting clamps downstream of the pressure and flow rate measurement sites. This yielded a regional flow distribution such that 73.2% of the flow passed through the descending aorta and 26.8% of the flow was distributed to the remaining arteries stemming from the aortic arch. The flow rates to individual arteries were also tuned to match that reported in the literature (30 (link), 31 (link)), which are summarized in Table 1.
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Publication 2023
A 078 Adult Arch of the Aorta Arteries BLOOD Blood Vessel Cardiac Arrest Cardiac Output Cardiovascular System Cerebral Arteries Cerebrovascular Accident Clotrimazole Descending Aorta Flowmeters Glycerin Nylons physiology Pressure Simulation Training Transducers, Pressure Ultrasonics Viscosity
BaPWV and cfPWV were measured by trained technicians using automated measuring equipment and following standardized protocols. BaPWV was measured using an automatic waveform analyzer (BP‐203RPE III, Colin‐Omron, Co., Ltd., Tokyo, Japan) based on a standard protocol. The subjects were in the supine position, and 4 cuffs were wrapped around the bilateral brachia and ankles and then connected to a plethysmographic sensor and oscillometric pressure sensor. The pulse waveform was recorded after resting for at least 5 min. BaPWV was measured on both the left and right sides, and the highest measured value was used for analysis.
The cfPWV was measured using an automated system (Pulse Pen, DiaTecne, Milan, Italy) with the patient in the supine position for 10 min. The right carotid and femoral waveforms were acquired simultaneously with two pressure‐sensitive transducers, and the transit time of the pulse was calculated using the system software. The distance between the two arterial sites was measured on the body using a tape measure, and the PWV values were calculated as distance divided by time (m/s).
Publication 2023
Ankle Arm, Upper Arteries Carotid Arteries Femur Oscillometry Patients Pressure Pulse Rate Transducers, Pressure

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PowerLab is a data acquisition system designed for recording and analyzing physiological signals. It provides a platform for connecting various sensors and transducers to a computer, allowing researchers and clinicians to capture and analyze biological data.
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The PowerLab system is a versatile data acquisition hardware platform designed for laboratory research and teaching applications. It offers a range of input channels and signal conditioning options to accommodate a variety of experimental setups. The PowerLab system is capable of recording and analyzing various physiological signals, enabling researchers to capture and study relevant data for their studies.
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LabChart 7 is a data acquisition and analysis software designed for recording, visualizing, and analyzing physiological signals. It provides a user-friendly interface for capturing data from various types of laboratory equipment and sensors. LabChart 7 offers tools for real-time display, analysis, and offline processing of the acquired data.
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The MP150 is a data acquisition system designed for recording physiological signals. It offers high-resolution data capture and features multiple input channels to accommodate a variety of sensor types. The MP150 is capable of acquiring and analyzing data from various biological and physical measurements.
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LabChart is a data acquisition and analysis software developed by ADInstruments. It allows users to record, display, and analyze physiological data from various instruments and sensors. The software provides a user-friendly interface for real-time data monitoring, signal processing, and visualization.
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LabVIEW is a software development environment for creating and deploying measurement and control systems. It utilizes a graphical programming language to design, test, and deploy virtual instruments on a variety of hardware platforms.
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A pressure transducer is a device that converts a pressure measurement into an electrical signal. It is used to monitor and record pressure in various applications.
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The PowerLab 8/30 is a high-performance data acquisition system designed for life science research. It features eight differential analog input channels and can sample data at up to 200 kHz per channel. The PowerLab 8/30 is capable of recording a wide range of physiological signals and is compatible with a variety of transducers and electrodes.
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The MLT0380 is a Muscle Transducer designed to measure the force generated by small muscle tissue samples. It features a force range of 0-2000 mN and a frequency response of DC to 1 kHz. The transducer is constructed with a compact and lightweight design for use in physiological research applications.

More about "Transducers, Pressure"

Pressure transducers, also known as force-to-electricity converters or displacement-to-electricity converters, are essential devices used to measure pressure in fluids, solids, and gases.
These instruments convert the energy of pressure or force into an electrical signal, enabling accurate measurements across a wide range of scientific and engineering applications.
Pressure transducers often utilize piezoelectric, resistive, or capacitive elements to generate an electric signal proportional to the applied pressure.
This principle is crucial for ensuring experimental reproducibility and optimization, as accurate measurement and comparison of pressure transducer performance is critical.
When conducting pressure-related experiments, researchers may utilize various data acquisition systems, such as the PowerLab system, MP150, or LabChart software.
These tools, often integrated with LabVIEW, provide a comprehensive platform for recording, analyzing, and interpreting pressure data from transducers.
The PowerLab data acquisition system, for example, is a versatile platform that can be paired with a wide range of pressure transducers, including the MLT0380.
The LabChart 7 software, in turn, allows users to seamlessly capture, visualize, and analyze pressure data, facilitating the optimization of experimental protocols and enhancing the overall research process.
By leveraging the insights gained from the MeSH term description and the provided metadescription, researchers can explore the nuances of pressure transducers, their applications, and the supporting tools and software available to enhance the accuracy, reproducibility, and efficiency of their experiments.