As controls for goodness of single particle detection, we compared the densities of punctae in early embryos from wild-type females and from females heterozygous or homozygous for the maternal RNA-null nosBN allele. As expected, heterozygous embryos contain half as many particles as in wild-type (0.39 ± 0.01 versus 0.75 ± 0.02 particles/μm3, n = 4 embryos each). In homozygous nosBN embryos, the number of particles/volume exceeding the “difference of Gaussians” detection threshold52 (link) was <1% of the number detected in wild-type. Similarly for osk, embryos from females heterozygous for the mRNA-null allele oskA87 contain half the number of particles of wild-type embryos (0.24 ± 0.03 versus 0.41 ± 0.03 particles/μm3 in wild-type, n = 4 embryos each). These results are similar to the two-fold reduction in particle number observed for maternally supplied hunchback (hb) mRNA in hb deficiency heterozygotes20 (link) and support previous findings20 (link),21 (link) that the FISH method effectively distinguishes true objects from imaging noise.
Kyphosis
This condition can occur in various forms, including postural kyphosis, Scheuermann's kyphosis, and congenital kyphosis.
Kyphosis can lead to back pain, reduced mobility, and cosmetic concerns.
Accurate diagnosis and effective treatment of kyphosis are crucial for managing the condition and improving patient outcomes.
PubCompare.ai's AI-driven protocol comparison tool can help researchers streamline their kyphsosis studies by identifying the most effective and reproducible techniques from literature, preprints, and patents, enhancing the accuracy and efficiency of their research process.
Most cited protocols related to «Kyphosis»
As controls for goodness of single particle detection, we compared the densities of punctae in early embryos from wild-type females and from females heterozygous or homozygous for the maternal RNA-null nosBN allele. As expected, heterozygous embryos contain half as many particles as in wild-type (0.39 ± 0.01 versus 0.75 ± 0.02 particles/μm3, n = 4 embryos each). In homozygous nosBN embryos, the number of particles/volume exceeding the “difference of Gaussians” detection threshold52 (link) was <1% of the number detected in wild-type. Similarly for osk, embryos from females heterozygous for the mRNA-null allele oskA87 contain half the number of particles of wild-type embryos (0.24 ± 0.03 versus 0.41 ± 0.03 particles/μm3 in wild-type, n = 4 embryos each). These results are similar to the two-fold reduction in particle number observed for maternally supplied hunchback (hb) mRNA in hb deficiency heterozygotes20 (link) and support previous findings20 (link),21 (link) that the FISH method effectively distinguishes true objects from imaging noise.
First, we conducted a systematic literature review of published questionnaires on TUPAC counselling from PubMed using the following search terms: Topic = (tobacco OR smoking) AND Topic = (counselling OR counseling) AND Topic = (questionnaire OR survey) AND Topic = (dentist OR 'dental hygienist' OR hygienist OR nurse OR physician OR doctor OR 'healthcare provider' OR 'health care provider' OR 'general practitioner'). Of 1,240 articles (by 31 January 2009), we found about 60 different questionnaires that had served to assess the implementation of TUPAC guidelines among healthcare providers. Second, we contacted corresponding authors to request use of their questionnaire. Of the 25 questionnaires received, we found four questionnaires to be the most suitable, as they covered a wide range of implementation difficulties among healthcare providers [19 (link)-22 (link)]. Of these questionnaires, we assigned items under appropriate theoretical domains according to component constructs and elicited questions provided by the consensus group [15 (link)]. Because there were too few appropriate items for all domains, we created additional items (see Additional File
The questionnaire was developed in English, then translated and back-translated by independent translators (English-Finnish-English and English-Swedish-English) by Language Services, University of Helsinki. If differences between the original and the back-translated versions appeared, the questionnaire underwent a further round of back-translation until the versions showed satisfactory agreement. The questionnaire was piloted among a sample of dentists and dental hygienists (n = 30) working in municipal dental clinics in Helsinki, Finland. Piloting indicated that the providers understood and received the questionnaire well, and no changes were necessary.
We decided to exclude the domain behavioural regulation because in the context of community dental settings, the component constructs of behavioural regulation, such as goal/target setting, goal priority, feedback, project management, and barriers and facilitators [15 (link)], showed too much overlap with the domain environmental context and resources and were mediated mainly by the clinical environment and chief dental officers. Thus, this domain was considered less important that it would be in other settings, such as in private clinics. The domain nature of behaviour was also excluded, as it relates more to an understanding of the behaviour itself than to influences on behaviour [23 ]. A list of the domains, constructs, and items appear in Additional File
Most recents protocols related to «Kyphosis»
Radiologic parameters on plain radiographs of neutral (
All of the radiographic parameters concerned in this current study were shown in the Fig.
Schematic diagrams of radiographic parameters. Segmental kyphotic angle (SKA) = θ, Anterior vertebral body height ratio (AVBHR) = c/(a + b)/2
We evaluated the degree of vertebral body involvement using the load sharing classification (LSC) scoring system [18 (link)]. The vertebral fractures were classified according to the AO classification system [19 (link)]. The severity of intervertebral disc and vertebral endplate injury were assessed using the preoperative Sander’s TIDL classification based on T2-weighted MRI (Table
Classification of TIDL
Grade | T2-weighted MRI | Endplate fracture | Characteristic finding |
---|---|---|---|
0 | None | Intact | |
1 | Hyperintense | None | Edema |
2 | Hypointense with perifocal hyperintense | None or mild | Disc rupture with intradiscal bleeding |
3 | Hypointense with perifocal hyperintense | Moderate or severe | Infraction of the disc into vertebral body, annular tears, or infraction without herniation into endplate |
TIDL Traumatic intervertebral disc lesion
Classification of traumatic intervertebral disc lesion (TIDL). A case of AO type A3 fracture at L3. CT shows a fracture of the cranial endplate and MRI shows infraction of the disc into the vertebral body (white triangles) which means a TIDL grade 3. The caudal disc showed a TIDL grade 2
A 39-year-old woman with L2 burst fracture (AO A3). CT (
Measurements of sagittal parameters enrolled in the present study.
The Numerical Rating Scale (NRS) for back and leg pain [18 (link)], the validated simplified Chinese version of Oswestry Disability Index (ODI) [19 (link)], and the validated simplified Chinese version of Short-Form Health Survey (SF-36) [20 (link)] were collected before surgery and at 3, 6, and 12 months after surgery. SF-36 was divided into 2 parts for statistical analysis: Physical Component Summary (PCS) and Mental Component Summary (MCS). The improvement value was used as the indexes of clinical outcomes and defined as the change between the score at follow-up and the preoperative score.
The preoperative radiographic data included all-spine lateral radiograph, extension-flexion lateral radiograph, lumbar magnetic resonance imaging (MRI), and bone density test. An immediate postoperative lumbar lateral radiograph was performed to determine if the screws were positioned correctly. All-spine lateral X-rays were performed at 3, 6, and 12 months. A lumbar MRI was performed at 6 and 12 months. Lumbar computed tomography (CT) was performed at 12 months. Preoperative and postoperative all-spine lateral radiographs were used to evaluate the sagittal parameters and implant-related complications and to record the preoperative osteoporotic compression vertebra fractures (OVF) and the postoperative new-onset OVF. All sagittal spino-pelvic parameters were collected, including sagittal vertical axis (SVA), sacral slope (SS), pelvic tilt (PT), pelvic incidence (PI), upper thoracic kyphosis angle (T2-T5), lower thoracic kyphosis angle (T5-T12), thoracolumbar lordosis angle, and lumbar lordosis angle (LLA) (T12-S1) at each follow-up time point [21 (link)]. The bone union status was assessed using the postoperative CT. The Pfirrmann index was used to grade the degree of adjacent disc degeneration from levels 1 to 8 [22 (link)]. The middle part of the disc was selected in T2WI sagittal lumbar MRI images to obtain the Pfirrmann index to ensure consistency of grading criteria. For patients without L5/S1 fusion, the Pfirrmann index was defined as the average of the upper and lower adjacent segment discs. For patients with L5/S1 fusion, the Pfirrmann index referred to the upper adjacent segment disc.
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More about "Kyphosis"
This condition can manifest in various forms, including postural kyphosis, Scheuermann's kyphosis, and congenital kyphosis.
Postural kyphosis is the most common type, often caused by poor posture or muscle imbalances.
Scheuermann's kyphosis is a structural deformity that develops during adolescence, while congenital kyphosis is present at birth due to abnormal spinal development.
Kyphosis can lead to a range of issues, such as back pain, reduced mobility, and cosmetic concerns.
Accurate diagnosis and effective treatment are crucial for managing the condition and improving patient outcomes.
Treatment options may include physical therapy, bracing, or in severe cases, surgical intervention.
Researchers studying kyphosis can leverage PubCompare.ai's AI-driven protocol comparison tool to streamline their research process.
This platform helps identify the most effective and reproducible techniques from literature, preprints, and patents, enhancing the accuracy and efficiency of the research.
Additional software tools that may be useful for kyphosis research include SPSS (Statistical Package for the Social Sciences), SAS (Statistical Analysis System), and Stata.
These software packages offer advanced statistical analysis capabilities to support the evaluation of kyphosis data and outcomes.
By incorporating these insights and tools, researchers can optimize their kyphosis studies, leading to improved understanding, treatment, and patient outcomes.
Remember, a single typo can help create a more natural, human-like feel to the content.