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> Disorders > Disease or Syndrome > Dissecting Aneurysms

Dissecting Aneurysms

Dissecting aneurysms are a type of arterial disorder characterized by the formation of a false lumen within the arterial wall, often resulting from a tear in the innermost layer.
This condition can lead to the separation of the arterial layers, posing a significant risk of rupture and life-threatening complications.
Understanding the underlying mechanisms and effective management strategies for dissecting aneurysms is crucial for improving patient outcomes.
PubCompare.ai's AI-driven platform can optimize research protocols, enhance reproducibility, and identify the best available protocols from literature, preprints, and patents, empowering researchers to advance the field of dissecting aneurysm research.

Most cited protocols related to «Dissecting Aneurysms»

1
Surgical Techniques for Aortic Root Repair in ATAAD

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Publication 2018
Adventitia Aorta Aortic Root Biopharmaceuticals Bites Connective Tissue Diseases Dacron Dissecting Aneurysms Dissection Feelings Grafts Heart Laceration Operative Surgical Procedures Patients Pigs Prolene Pseudoaneurysm Reconstructive Surgical Procedures Sinotubular Junction Sinus, Aortic Sinus, Coronary Surgeons Surgical Anastomoses Surgical Replantation Sutures Thrombus Tissues Tooth Root Toxins, Biological Tunica Intima Valves, Aortic
2
Aortic Stenosis Hemodynamics and Outcomes

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Publication 2020
Aorta Aortic Valve Insufficiency Cardiologists Coarctation, Aortic Dietary Supplements Dissecting Aneurysms Echocardiography Left Ventricles Mitral Valve Insufficiency Operative Surgical Procedures Patients Pharmaceutical Preparations Primary Health Care Prosthesis Stroke Volume Subvalvular Stenoses, Aortic Surgical Replantation Transcatheter Aortic Valve Replacement Valves, Aortic Valves, Surgical
3
Laparoscopic Surgical Skills Training Using Porcine Organs
The institutional review board approved the present study (No. 018-0257). As described above, we previously reported our wet-lab training using cadaveric porcine organs. Briefly, participants performed three tasks: Task 1: tissue dissection around the aorta, dividing encountered mesenteric vessels after applying a Hem-o-lok, Task 2: tissue dissection and division of the renal artery, and Task 3: renal parenchymal closure. We observed good construct validity based on Global Operative Assessment of Laparoscopic Skills (GOALS) and our original assessment sheet, by two blinded experts’ video reviews of all three tasks [1 ]. We used Task 1 and a modified Task 3 for the present Mocap analysis. Forty-five subjects voluntarily participated in the training. Written informed consent was obtained regarding the use of their data for research. The details of the present training tasks are described in the next paragraph. In all tasks, porcine cadaveric organs were placed in a box trainer (Endowork Pro®, Kyoto Kagaku, Japan, Fig. 1A, B). Porcine organs were purchased from a commercial vendor. Before the training, each task was explained by one of the authors (KE) using recorded movies. During the training, one of the four authors (TA, MH, JF, and NI) was a scopist, using a video system (VISERA Pro Video System Center OTV-S7Pro, Olympus, Japan, Fig. 1A) and zero-degree lens. If participants had problems with simulation, especially medical students, each step of the training task was verbally guided by the scopist. After the training session, completed questionnaires were collected, including demographic data and experience of laparoscopic surgeries. In Japan, the Endoscopic Surgical Skill Qualification (ESSQ) system was initiated in 2004, in which two double-blinded referees evaluate an unedited surgical movie [16 (link), 17 (link)], and this certification status was also ascertained. All training sessions were video-recorded, and the subjective mental workload was assessed by NASA Task Load Index after each training session for subsequent analysis.

Photographs of the swine organ training model. A Swine aorta set in a dry box trainer. B Swine kidney set in a dry box trainer. C Task 1, a view of tissue dissection. D Task 1, a view of applying a Hem-o-lok. E Task 2, a view of needle driving. F Task 3, a view of making a knot

Ebina K., Abe T., Higuchi M., Furumido J., Iwahara N., Kon M., Hotta K., Komizunai S., Kurashima Y., Kikuchi H., Matsumoto R., Osawa T., Murai S., Tsujita T., Sase K., Chen X., Konno A, & Shinohara N. (2020). Motion analysis for better understanding of psychomotor skills in laparoscopy: objective assessment-based simulation training using animal organs. Surgical Endoscopy, 35(8), 4399-4416.
Publication 2020
Aorta Blood Vessel Dissecting Aneurysms Dissection Ethics Committees, Research Kidney Laparoscopy Lens, Crystalline Mesentery Mocap Needles Operative Surgical Procedures Pigs Renal Artery Students, Medical Surgical Endoscopy Surgical Procedures, Laparoscopic Tissues
4
Aortic Diameter Measurement and Dissection Detection
Aortic diameter measurements and dissection-flap recognition were obtained via ultrasound imaging at 40 MHz using the Vevo 770 ultrasound system (Visualsonics, Toronto) in a blind manner for each medication group. All ultrasound measurements of aortic diameters were performed by a single investigator and had an inter-measurement variation of less than 2%. Imaging was performed prior to Ang II infusion and on days 3, 7, 14, 21 and 28 thereafter. An AAA was defined as a ≥50% increase in aortic diameter or the presence of aortic dissection. Mice were daily monitored for mortality analysis. Dead mice were subjected to necropsy within 12 h to confirm presence or absence of aortic rupture.
Iida Y., Xu B., Schultz G.M., Chow V., White J.J., Sulaimon S., Hezi-Yamit A., Peterson S.R, & Dalman R.L. (2012). Efficacy and Mechanism of Angiotensin II Receptor Blocker Treatment in Experimental Abdominal Aortic Aneurysms. PLoS ONE, 7(12), e49642.
Publication 2012
Aorta Aortic Rupture Autopsy Dissecting Aneurysms Dissection Mus Pharmaceutical Preparations Surgical Flaps Ultrasonography Visually Impaired Persons
5
Surgical Repair for Acute Aortic Dissection
The general principles of aortic repair procedures are detailed in previous studies reported by this institute10 (link),11 (link). For uncomplicated ATAAD patients who were considered relatively stable, double arterial cannulation with antegrade cerebral perfusion (ACP) strategy was usually implemented. The right axillary and femoral arteries were cannulated with an 8-mm ring-reinforced polytetrafluoroethylene graft and connected with a Y-shape circuit. Following sternotomy, the right atrium was cannulated and cardiopulmonary bypass (CPB) with deep hypothermia was initiated. In general, the dissected aorta was replaced with a Dacron prosthetic graft based on the location of the entry tear and preoperative presentation. The proximal anastomosis was usually performed first, followed by open distal anastomosis under circulatory arrest. During circulatory arrest, the femoral arterial flow was temporarily suspended and selective ACP through the right axillary artery was used. Concomitant aortic root replacement with a composite Valsalva graft and frozen elephant trunk procedure with a covered stent graft were performed if the extent of aortic dissection involved the aortic root and descending thoracic aorta, respectively. After undergoing surgical repair for ATAAD, all patients were transferred to a specialized cardiovascular intensive care unit (ICU) for further treatment and observation. Without unstable haemodynamics, persistent arrhythmia, signs of organ malperfusion, or active bleeding, a ventilator-weaning protocol was initiated at 12–24 h post surgery. Renal replacement therapy was applied according to the Acute Kidney Injury Network criteria if acute renal failure developed after surgery12 (link).
Lin C.Y., See L.C., Tseng C.N., Wu M.Y., Han Y., Lu C.H, & Tsai F.C. (2020). Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience. Scientific Reports, 10, 14883.
Publication 2020
Aorta Aortic Root Arteries Atrium, Right Axilla Cannulation Cardiac Arrest Cardiac Arrhythmia Cardiopulmonary Bypass Cardiovascular System Cerebral Arteries Dacron Dissecting Aneurysms Elephants Femoral Artery Femur Freezing Grafts Hemodynamics Kidney Failure, Acute Laceration Operative Surgical Procedures Patients Perfusion Polytetrafluoroethylene Renal Replacement Therapy Stents Sternotomy Surgical Anastomoses Thoracic Aorta

Most recents protocols related to «Dissecting Aneurysms»

1
Cross-sectional study of Shanghai population
The study subjects (n = 13,750) were enrolled through cluster multistage and random sampling to community population from several districts of Shanghai in China in this cross-sectional study. The participants aged more than 18 years old were investigated in each center from May to September in 2016. Exclusion criteria included history of aortic dissection, history of amputation surgery, atrial fibrillation, mental disorder or lack of compliance. After the subjects with incomplete data or exclusion criteria were removed, there were totally 13,144 participants left (Fig. 1).

Flow chart of subjects enrollment

The study complied with the Declaration of Helsinki. It was also approved by the ethics committee of Shanghai Jiao Tong University and informed consent was obtained from all the participants prior to enrollment.
Wang Y., Guo X., Zhang Y., Zhang R, & Li J. (2023). Different associations of general and abdominal obesity with upper and lower extremity artery disease among a community population in China. Nutrition & Metabolism, 20, 14.
Publication 2023
Amputation Atrial Fibrillation Dissecting Aneurysms Ethics Committees Mental Disorders
2
Aortic Dissection Complications Protocol
A bibliometric literature search was performed online using the Web of Science Core Collection (WoSCC) on May 27, 2022, with the time span for publication set to 1991 to 2022. Three Medical Subject Headings terms were used for the search. Term A was “aortic dissection,” Term B was “complication,” and Term C was “postoperative.” The search criteria for the included publications were the following: TS = (aortic dissection) AND TS = (complication) AND TS = (postoperative). Among the types of documents included were original research articles and reviews (including meta-analysis) written in English. The exclusion criteria were as follows: repeated published literature; and non-English literature. A total of 1242 articles were included in the study, and the literature was exported and saved. All records and references were formatted and stored as plain text files in.txt format.
Feng D., Huang S., Wang Q., Lang X., Liu Y, & Zhang K. (2023). Hotspots and development frontiers of postoperative complications of AD: Bibliometric analysis – a review. Medicine, 102(10), e33160.
Publication 2023
Dissecting Aneurysms
3
Observational Study of Idiopathic Aortic Dissection
The prospective cohort study was reported in line with Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) (4 (link)). The study was approved by the Institutional Review Board (KY-Q-2021-073-01), with informed consent not required due to its observational nature.
All consecutive patients admitted to the Guangdong Provincial People’s Hospital (Guangdong, China) from January 2016 to April 2021 were enrolled and followed up prospectively. Anthropometric, radiologic, laboratory, and operative data were manually accrued from individual electronic medical records and hospital charts. If there were missing values, we would check with the patient or relatives by phone. Computed Tomography Angiography (CTA) was used to confirm IAAD, demonstrating dissected intimal flap and double-lumen aorta below the diaphragm, with or without visible entry tear. Hypertension was diagnosed according to medical history as blood pressure measured at 140/90 mmHg or higher. Diameter was measured perpendicular to the centerline at the different levels in an outer-to-outer manner, and the maximum was noted. The thrombosis status of false lumen was classified as complete thrombosis (CT), partial thrombosis (PT, concurrent presence of both flow and thrombus), and patency (P) proposed by Tsai et al. (5 (link)). Accidental identification of IAAD indicated that the disease was diagnosed by chance such as routinely physical examination or undergoing imaging not specifically for aortic disease. Those patients usually had no symptoms and the aortic dissection was in chronic phase (6 (link)).
There was a lack of recognized protocol for the optimal management of IAAD. Patients were treated either conservatively with best medical therapy (BMT), or aggressively with OS or EVAR, based on attending surgeon’s judgment and patients’ preference. All-cause death was taken as the primary endpoint and surgical intervention for BMT cohort as the secondary endpoint. Patients were followed up either with clinical visits or phone calls.
Wu J., Wu Y., Li F., Zhuang D., Cheng Y., Chen Z., Yang J., Liu J., Li X., Fan R, & Sun T. (2023). Natural history of isolated abdominal aortic dissection: A prospective cohort study. Frontiers in Cardiovascular Medicine, 10, 1002832.
Publication 2023
Accidents Aorta Aortic Diseases Blood Pressure Computed Tomography Angiography Dissecting Aneurysms Ethics Committees, Research High Blood Pressures Patients Physical Examination Respiratory Diaphragm Surgeons Surgical Flaps Tears Therapeutics Thrombosis Thrombus Tunica Intima
4
Aortic Diameter Monitoring in Mice
A high-resolution Vevo 2100 microimaging system (Visualsonic) was used to measure the aortic diameter in each group of mice on days 0 and 28. A suprarenal aortic diameter increase of ≥50% or the occurrence of aortic dissection (AD) in the mice was considered aneurysmal. Furthermore, the survival ratios were monitored daily, and a Softron BP-2010 Series system (a non-invasive tail-cuff system) was used to measure the systolic blood pressure on days 0 and 28.
Xiao J., Wei Z., Yang C., Dai S., Wang X, & Shang Y. (2023). The gut microbiota in experimental abdominal aortic aneurysm. Frontiers in Cardiovascular Medicine, 10, 1051648.
Publication 2023
Aneurysm Aorta Dissecting Aneurysms Mus Systolic Pressure Tail
5
Postoperative Delirium in Aortic Dissection
(I) Type of study: study on influencing factors of postoperative delirium in patients with acute type A aortic dissection; (II) subjects: patients with acute type A aortic dissection diagnosed according to cardiovascular imaging technology, who developed delirium after surgery and survived during postoperative hospitalization; (III) outcomes: the data in the included literatures are complete and may have extractable or converted risk factors.
Wang S., Wang T., Zhao C, & Lin D. (2023). Systematic review and meta-analysis of the risk factors for postoperative delirium in patients with acute type A aortic dissection. Journal of Thoracic Disease, 15(2), 668-678.
Publication 2023
Cardiovascular System Delirium Dissecting Aneurysms Emergence Delirium Hospitalization Operative Surgical Procedures Patients

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More about "Dissecting Aneurysms"

Dissecting aneurysms, also known as aortic dissections, are a serious and life-threatening type of arterial disorder characterized by the formation of a false lumen or channel within the arterial wall.
This condition typically arises from a tear or disruption in the innermost layer of the artery, allowing blood to flow between the layers and separate them.
Aortic dissections can have devastating consequences, including the risk of rupture and catastrophic bleeding, which can lead to severe complications and even death.
Understanding the underlying mechanisms, risk factors, and effective management strategies for dissecting aneurysms is crucial for improving patient outcomes.
Researchers and clinicians utilize a variety of tools and techniques to study and manage dissecting aneurysms, such as Spot Vital Signs LXi for monitoring vital signs, Collagenase type I for enzymatic tissue digestion, Crenolanib for targeted drug therapy, HumanHT-12 V4.0 expression beadchip for gene expression analysis, Image-Pro Plus for digital image processing, TD.88137 for statistical analysis, SPSS Statistics version 21 for advanced data analysis, and the Human Genome U133 Plus 2.0 Array for comprehensive genomic profiling.
Imaging modalities like the Somatom Definition CT scanner also play a critical role in the diagnosis and monitoring of dissecting aneurysms.
By leveraging these advanced technologies and research methods, scientists and healthcare providers can gain deeper insights into the mechanisms and management of this complex condition, ultimately working to improve patient outcomes and reduce the burden of dissecting aneurysms.
PubCompare.ai's AI-driven platform can further optimize the research process by enhancing protocol reproducibility, identifying the best available protocols from literature, preprints, and patents, and empowering researchers to advance the field of dissecting aneurysm research.
With its cutting-edge technology, PubCompare.ai can help researchers and clinicians streamline their efforts and make meaningful progress in understanding and treating this serious arterial disorder.