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Hemangioma

Hemangioma is a common vascular anomaly characterized by the proliferation of endothelial cells, forming a benign tumor-like growth.
These lesions can occur in various parts of the body, including the skin, mucous membranes, and internal organs.
Hemangiomas typically appear in infancy and often undergo spontaneous involution over time.
Understanding the pathogenesis and clinical management of hemangiomas is crucial for healthcare professionals, as these lesions can cause cosmetic concerns, functional impairments, or even life-threatening complications in some cases.
Researching the latest advancements in hemangioma treatment, including the use of pharmacological agents and surgical interventions, is essential for providing optimal patient care.
The PubCompare.ai platform can streamline this process by helping researchers identify the most reliable and up-to-date protocols from the literature, preprints, and patents, ultimately enhancing the quality and reproducibility of hemangioma-related studies.

Most cited protocols related to «Hemangioma»

Asynchronous QCT was performed in baseline CT, a technique that provides results comparable to conventional QCT [26 (link)]. Attenuation values in HU were manually sampled with tools of the institutional picture archiving and communication system software (Sectra IDS7, Sectra AB) and transformed into volumetric BMD with conversion equations calculated by asynchronous calibration. An experienced radiologist placed a circular region of interest in trabecular bone of lumbar vertebrae L1 to L4, as previously described [27 ], using on-the-fly calculated midsagittal stacks of 15-mm thickness. Sampled HU was averaged over assessed vertebrae, omitting fractured vertebra or those with apparent alterations of the trabecular bone due to degeneration or hemangioma.
HU-to-BMD conversion equations were calculated by linear regression, in three scanners (Philips Brilliance 64, iCT 256, and Siemens Somatom Definition AS+) based on measurements of density-reference phantoms (QRM) in dedicated scans with the same tube voltage and scanner settings as in clinical routine acquisitions, and in two already decommissioned scanners (Siemens Somatom Definition AS and Sensation Cardiac 64) based on retrospective measurements of a density-reference phantom (Osteo Phantom, Siemens Healthineers), which had been included in the scanner couch during clinical CT scans for a certain period of time in the past (Fig. 2). Retrospective measurements of the Siemens Osteo phantom and a second calibration phantom (Mindways Software) were performed in CT exams, which were randomly selected from the institutional database in 2-month intervals over the entire time period when phantoms were present. Thereby, long-term scanner stability was evaluated in three scanners (Philips iCT 256, Siemens Somaton Definition AS, and Sensation Cardiac 64). Conversion equations and long-term stability measures are shown in Table 4. A BMD correction offset for contrast-enhanced CT scans with arterial (− 8.6 mg/cm3) and portal venous contrast phase (− 15.8 mg/cm3) was added based on previous investigations [28 (link)]. Osteoporosis was defined as BMD < 80 mg/cm3 and osteopenia as 80 ≤ BMD ≤ 120 mg/cm3 [29 ].

Routine CT scan of a 63-year-old female patient for follow-up purpose after metastatic gastric cancer and liver transplant with administration of oral and intravenous contrast medium in portal venous phase. For two MDCT scanners (Siemens Somatom Definition AS [in this example] and Sensation Cardiac 64), retrospective measurements of an in-plane calibration phantom present underneath patients during routine scans were used for asynchronous calibration and evaluation of long-term scanner stability

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Publication 2019
Administration, Oral Arteries Cancellous Bone Gastric Cancer Heart Hemangioma Liver Transplantations Microscopy, Phase-Contrast Multidetector Computed Tomography Neoplasm Metastasis Osteopenia Osteoporosis Patients Radiologist Radionuclide Imaging Spinal Fractures Stomach Veins, Portal Vertebra Vertebrae, Lumbar Woman X-Ray Computed Tomography
Three radiologists, all with >10 years of experience in
musculoskeletal MRI, independently evaluated the images. The first
observer to open the MRI examination saved a mark on the lowest lumbar
disc level. All observers reported this level as L5/S1. First, MCs
were rated on T1/T2, blinded to other sequences. Later the observers
rated STIR findings and decided whether any increased STIR signal was
related to an MC visible on T1/T2. The observers were blinded to
clinical outcome but knew that patients were preliminarily eligible
for the trial. To align their understanding of procedures and rating
criteria, the observers rated and discussed MCs and STIR findings in a
pilot study (32 MRIs not included in the main study).
On T1/T2, we defined MCs as signal changes in the vertebral bone marrow
extending from the endplate, and based rating criteria for MC type and
size on prior work (10 ,11 (link),38 (link),45 (link)) (Table 2). Only T1/T2
findings defined MC types I, II and III, not STIR findings. Not
recorded as MCs were: (i) changes separated from the endplate; (ii)
roundly shaped fatty changes abutting the endplate with a smaller base
than height (more likely focal fatty marrow or hemangiomas); and (iii)
changes extending through the endplate (Schmorl’s hernias).
On STIR, we defined MC-related signal increase as visible increase
compared to normal vertebral bone marrow, formed and located as an MC
and/or located in or abutting a region with MC on T1/T2 (and not
located in a likely hemangioma). MC-related STIR signal increase was
evaluated for presence, height, anteroposterior (AP) extent, volume,
and maximum intensity (Table 2). STIR signal
decrease was not evaluated. STIR signal intensity was measured in the
region with most intense MC-related STIR signal, in the cerebrospinal
fluid (CSF) and in normal vertebral body marrow (Table 2,
Fig. 1).
The measurements were made in circular regions of interest available
in our PACS with size 25 mm2 (used for most intense
MC-related STIR signal and CSF) and 44 mm2 (used for normal
vertebral body marrow) (Fig. 1). Care was taken to
avoid surrounding structures, e.g. intervertebral discs, nerve roots,
central vertebral vein. Intensity of CSF varied between levels and was
measured at the same disc level as the MC-related STIR signal. Maximum
intensity of the MC-related STIR signal (“Stir”) in % points on a
scale from normal vertebral body intensity (“Body,” 0%) to CSF
intensity (“CSF,” 100%) was calculated as ((Stir – Body)/(CSF –
Body)) × 100.
Publication 2020
Atrial Premature Complexes Bone Marrow Hemangioma Hernia Human Body Intervertebral Disc Magnetic Resonance Imaging Marrow Nervousness Patients Plant Roots Radiologist Veins Vertebra Vertebral Body
Patients answered each question by themselves. This study included patients with cervical myelopathy secondary to cervical disc herniation, spondylosis, ossification of the posterior longitudinal ligament, calcification of the ligament flavum, spinal cord tumor, and developmental spinal canal stenosis. Patients with the following disorders were excluded: cervical spondylotic amyotrophy, cervical radiculopathy, disorders of the upper cervical spine such as atlantoaxial subluxation, spinal tumor, vascular lesions of the cervical spinal cord, cervical hemangioma, syringomyelia, multiple sclerosis, motor neuron disease, myelitis, and spinal cord injury. Patients with disturbances of the central nervous system such as cerebral infarction, combined cervical and thoracic spine lesions, orthopedic disorders other than cervical myelopathy, and cognitive disorders, and patients who could not complete the questionnaire because of defects of the arm, fingers, or foot, were also excluded. Patients whose condition resulted from occupational accidents, traffic accidents, or injuries were excluded.
The investigation period was 4 weeks from the start of the present study at each institution. All patients were asked to participate in the survey and were told that the questionnaire would be used to develop a new JOA score. Only patients who agreed to join the study answered the questionnaire.
Publication 2007
Blood Vessel Calcinosis Central Nervous System Cerebral Infarction Cervix Diseases Cognition Disorders Fingers Foot Hemangioma Injuries Intervertebral Disk Displacement Joint Subluxations Ligaments, Flaval Motor Neuron Disease Multiple Sclerosis Muscular Atrophy Musculoskeletal Diseases Myelitis Neck Occupational Accident Ossification of Posterior Longitudinal Ligament Patients Pulp Canals Radiculopathy, Cervical Spinal Cord Diseases Spinal Cord Injuries Spinal Cord Neoplasms Spinal Cords, Cervical Spinal Diseases Spinal Stenosis Spondylosis Spondylosis, Cervical Syringomyelia Traffic Accidents Vertebral Column

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Publication 2014
Adult Biopsy Cells Hemangioma Immunohistochemistry Patients Skin

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Publication 2013
Autopsy Cancer of Liver Cholelithiasis Ethics Committees, Research Females Freezing Hemangioma Hepatectomy Homo sapiens Liver Males Patients RNA, Messenger Tissues

Most recents protocols related to «Hemangioma»

The diagnosis of anal fistula is based on the German S3 guidelines: anal abscess and fistula (23 (link)). All patients were diagnosed with anal fistula by anal finger examination, anoscope examination, radiographic examination (including rectal endoluminal ultrasound, pelvic CT, or MRI), or intraoperative probe/methylene blue staining, and the number of internal orifices was counted by these techniques. The diagnostic criteria for T2DM were based on the latest Chinese guidelines for the prevention and treatment of T2DM set by the Chinese Diabetes Society (24 (link), 25 (link)). And the diagnosis was assigned by an endocrinologist. Relevant data were collected on the cases, including demographic characteristics, clinical features, laboratory and ancillary tests at admission, anal fistula-related information (e.g., previous surgical history, anal fistula types, number of internal orifices, etc.), pre- and post-surgical treatments, and surgical modalities. Non-healing (refractory) group refers to trauma that cannot be repaired in time with conventional therapy or wounds that can not achieve functional recovery and anatomical integrity (26 (link)). The last routine dressing change time in the outpatient clinic was collected as the outcome indicator. Judged by the specialist anorectologist and the definition of the relevant literature, patients were divided into the non-healing (refractory) group or healing group according to whether its recovery period is longer than 35 days (27 (link)–29 (link)).
Among the underlying diseases, hypertensive disease and non-alcoholic fatty liver diseases are listed independently. Chronic cardiovascular diseases included coronary atherosclerotic heart disease and lacunar cerebral infarction. Chronic lung diseases included tuberculosis, chronic obstructive pulmonary disease, and chronic pulmonary heart disease. Chronic liver diseases included chronic viral hepatitis B, cirrhosis of the liver, hepatic hemangioma, etc.
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Publication 2023
Abscess Anal Fistula Anus Cardiovascular Diseases Cardiovascular System Chinese Chronic Obstructive Airway Disease Coronary Arteriosclerosis Cor Pulmonale Diabetes Mellitus Diagnosis Disease, Chronic Endocrinologists Fingers Fistula Heart Hemangioma Hepatitis B, Chronic High Blood Pressures Hospital Admission Tests Liver Liver Cirrhosis Liver Diseases Lung Lung Diseases Methylene Blue Non-alcoholic Fatty Liver Disease Operative Surgical Procedures Patients Pelvis Recovery of Function Rectum Stroke, Lacunar Therapeutics Tuberculosis Ultrasonics Wounds Wounds and Injuries X-Rays, Diagnostic
All procedures and protocols were conducted in accordance with the principles of Helsinki Declaration, written informed consent was obtained from all participants in accordance with standard operative procedures. The study was approved by the Clinical Hospital Center Zemun- Belgrade by the number of approval 8946.
The present study was an observational cohort study of 60 patients who were prospectively recruited and divided into two groups. Patients were hospitalized at the Department of Neurosurgery at Clinical Hospital Center Zemun between 2020 and 2021 and were operated with surgical indications of lumbar disc herniation (LDH) and lumbar spinal stenosis (LSS). All patients fulfilled the following criteria: 1. Age > 18 years, 2. No previous surgery on spine, 3. Diagnosis was verified by magnetic resonance imaging. Patients with history of osteoporosis, immunosuppression, chronic corticosteroid use, intravenous drug use, fever of unknown origin, history of malignancy, unexplained weight loss, or progressive/disabling symptoms were excluded from the study. All patients were operated by one neurosurgeon (V. A.). The LF samples were obtained from the 60 patients randomized in 2 groups. The first group underwent micro-discectomy for LDH and included LF samples from 30 patients (LDH group). The second group underwent decompressive surgery without instrumented fusion for LSS and included LF samples from 30 patients (LSS group). In the patients with multisegmental stenosis, samples were taken from the radiologically determined site of greatest stenosis. While every effort was made to remove the LF en-bloc, in the majority of cases, the LF was removed piecemeal.
Demographic and clinical data were obtained using a pre-prepared questionnaire as well as data from medical history. Morphological/radiological data were obtained by measuring specific parameters on magnetic resonance imaging—T2 sequences, performed by two experienced radiologists, after several repeated measurements. The examined morphological/radiological parameters measured on the sagittal image projection of the lumbosacral spine region were presence of Schmorl's nodes, vertebral body hemangioma, spondylolisthesis, and value of lumbar lordosis angle. Other measurements were performed at the axial image section where the degree of discal herniation or spinal stenosis were most prominent and included: interfacet distance, thickness of LF on both sides, dural laterolateral (LL) diameter and anteroposterior (AP) diameter of dural sac, average facet joint angle, and dural sac surface. The scoliosis angle was also determined using the standard Cobbs method on the coronary sections of spine magnetic resonance imaging of the patients30 (link). Spondylolisthesis was determined as a percentage of vertebral body slippage. Lumbar lordosis angle was also determined using the standard Cobbs method30 (link). The determination of the other mentioned parameters is shown in Fig. 2.

Measurement of (A) ligamentous interfacet distance, (B) anteroposterior diameter of dural sac, (C) laterolateral diameter of dural sac, (D) thickness of LF on both sides, (E) average facet joint angle measured according to formula: (a + b)/2, (F) dural sac surface.

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Publication 2023
Adrenal Cortex Hormones Diagnosis Diskectomy Facet Joint Fever of Unknown Origin Heart Hemangioma Immunosuppression Intervertebral Disk Displacement Laminectomy Ligaments Lordosis Lumbar Region Lumbosacral Region Malignant Neoplasms Neurosurgeon Neurosurgical Procedures Operative Surgical Procedures Osteoporosis Patients Pharmaceutical Preparations Radiologist Scoliosis Spinal Stenosis Spondylolisthesis Stenosis Vertebral Body Vertebral Column X-Rays, Diagnostic
This retrospective study was reviewed and approved by the institutional review board. All the patients enrolled in this study were recruited from two independent institutions: the Second Affiliated Hospital of Zhejiang University, from February 2009 to June 2020, and Tianjin Medical University Eye Hospital, from December 2017 to May 2018. The inclusion criteria were as follows: (1) histopathological diagnosis of hemangioma or lymphoma based on the excised tissues from the orbital lesions and (2) patients with non–contrast-enhanced CT images before surgery. The exclusion criteria were: (1) patients with unclear histopathological results; (2) poor CT image quality or without CT images in axial view; and (3) history of eye or orbital surgery, trauma, radiation treatment, or other orbital therapy.
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Publication 2023
Diagnosis Ethics Committees, Research Hemangioma Lymphoma Operative Surgical Procedures Patients Radiotherapy Therapeutics Tissues Wounds and Injuries
Matched peripheral blood and tumor-free liver samples were obtained from patients at the Asklepios Hospital Barmbek (AKB) undergoing extended liver resection due to liver metastases following colorectal cancer, liver adenoma, cholangiocellular carcinoma or hemangioma (n=17), and at the University Medical Center Hamburg-Eppendorf (UKE) from patients undergoing liver transplantation (n=17) due to end-stage liver disease. Human control peripheral blood samples were obtained from 13 healthy individuals. Furthermore, residual amounts of anonymized peripheral blood samples (buffy coats) from 12 randomly-selected healthy blood donors recruited at the Institute for Transfusion Medicine at the UKE were used. All blood donors gave their general written consent to use their blood samples for scientific studies. The anonymized use of buffy coats complied with a vote by the ethics committee of the German Medical Association. Study protocols (PV4898, PV4081, and PV4780) were approved by the ethics committee of the medical association of Hamburg, and all study participants provided written informed consent. The demographics and clinical characteristics of study participants are summarized in Tables 1, 2.
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Publication 2023
BLOOD Cholangiocarcinoma Colorectal Carcinoma Donor, Blood End Stage Liver Disease Ethics Committees Hemangioma Hepatectomy Hepatocellular Adenoma Homo sapiens Liver Transplantations Neoplasm Metastasis Neoplasms, Liver Patients
A total of 59 paraffin-embedded liver sections, including samples from 18 HCs to 41 patients with PBC, were obtained from Xiangya Hospital (Changsha, Hunan, China) between February 2017 and September 2022. Patients with PBC were diagnosed by experienced physicians based on levels of serum alkaline phosphatase (ALP), status of serum AMAs, and histological evaluation of biopsied liver tissue. The histological sections were evaluated by experienced hepatopathologists in a blinded fashion and the stages of PBC, degree of fibrosis, and bile duct loss in each sample were scored using the Ludwig (Ludwig et al., 1978 (link)) and Nakanuma systems (Nakanuma et al., 2010 (link)). The control liver sections were obtained from normal liver tissues without unusual histological features, such as hepatic hemangioma, and nontumoral parts of livers complicated with a liver tumor. The detailed clinical characteristics of the enrolled patients are listed in Supplementary Table S1.
This study was approved by the Ethics Review Board of Xiangya Hospital Central South University (No. 20221025). Written informed consent was obtained from all participants.
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Publication 2023
Alkaline Phosphatase Duct, Bile Fibrosis Hemangioma Liver Neoplasms, Liver Paraffin Embedding Patients Physicians Serum Tissues

Top products related to «Hemangioma»

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More about "Hemangioma"

Hemangiomas are a common type of vascular anomaly characterized by the proliferation of endothelial cells, forming a benign tumor-like growth.
These lesions can occur in various parts of the body, including the skin, mucous membranes, and internal organs.
Hemangiomas typically appear in infancy and often undergo spontaneous involution over time.
Understanding the pathogenesis and clinical management of hemangiomas is crucial for healthcare professionals, as these lesions can cause cosmetic concerns, functional impairments, or even life-threatening complications in some cases.
Researching the latest advancements in hemangioma treatment, including the use of pharmacological agents and surgical interventions, is essential for providing optimal patient care.
The PubCompare.ai platform can streamline this process by helping researchers identify the most reliable and up-to-date protocols from the literature, preprints, and patents, ultimately enhancing the quality and reproducibility of hemangioma-related studies.
This AI-driven platform utilizes cutting-edge technology to assist researchers in locating the best protocols, improving the efficiency and accuracy of their work.
When studying hemangiomas, researchers may employ various techniques and materials, such as FBS (Fetal Bovine Serum), DMEM (Dulbecco's Modified Eagle Medium), Image-Pro Plus 6.0 software, TRIzol reagent for RNA extraction, Endothelial Cell Growth Medium-2 (EGM-2) for cell culture, Matrigel for in vitro angiogenesis assays, Isolectin B4 (lectin) (Alexa Fluor 594 – I21413) for vascular staining, Penicillin/streptomycin for cell culture, and SAS 9.4 for statistical analysis.
These tools and materials are commonly used in hemangioma research to ensure reliable and reproducible results.
By utilizing the PubCompare.ai platform and incorporating the latest advancements in hemangioma research, healthcare professionals can enhance their understanding of this condition and provide more effective treatment options for patients.
Whether the goal is to address cosmetic concerns, manage functional impairments, or prevent life-threatening complications, the insights gained through comprehensive research can make a significant difference in the lives of those affected by hemangiomas.