The largest database of trusted experimental protocols
> Disorders > Pathologic Function > Physiological Stress

Physiological Stress

Physiological Stress: The body's adaptive response to internal or external forces of a physical, mental, or emotional nature, which creates a state of threatened homeostasis.
This response is characterized by a release of catecholamines and corticosteroids, and an increase in heart rate, blood pressure, respiration, and metabolism.
Physiological stress is an important factor in the development and progression of many health conditions, includeing cardiovascular disease, metabolic disorders, and mental health issues.
Understanding and assessing physiological stress is crucial for optimizing health outcomes and enhancing reasearch reproducibility.
Leverge the power of AI-driven platforms like PubCompare.ai to streamline your physiological stress research and identify the most effective aprpoaches.

Most cited protocols related to «Physiological Stress»

Protocol full text hidden due to copyright restrictions

Open the protocol to access the free full text link

Publication 2016
Age Groups Air Pollutants Body Temperature Changes Child Cuboid Bone Diagnosis Humidity Hypersensitivity Physiological Stress Pressure Vorinostat Wind

Protocol full text hidden due to copyright restrictions

Open the protocol to access the free full text link

Publication 2016
Arteries Blood Pressure Collagen Cytosol Elastic Fibers Extracellular Matrix Helix (Snails) Human Body Myocytes, Smooth Muscle Physiological Stress Strains

Protocol full text hidden due to copyright restrictions

Open the protocol to access the free full text link

Publication 2016
Biological Assay BLOOD Blood Platelets Citrates Donors Enzyme-Linked Immunosorbent Assay Healthy Volunteers Homo sapiens Inositol Phosphates Physiological Stress Platelet-Rich Plasma Thrombosis trimethyloxamine
The VA Pittsburgh Healthcare System institutional review board determined this analysis to be exempt because data were deidentified; thus, no consent was needed. This study follows the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guideline.
This cohort study used data from the Veterans Affairs Surgical Quality Improvement Program for noncardiac surgical procedures performed between April 1, 2010, and March 31, 2014, for veterans with available 1-year postoperative vital status. Exposures of interest were urgency (emergent vs elective), frailty (measured by the Risk Analysis Index [RAI]), and operative stress (measured by the Operative Stress Score [OSS]). Operative urgency was defined by the binary Veterans Affairs Surgical Quality Improvement Program variable for emergent operations. The RAI is based on the accumulation of deficits model of frailty and uses demographic factors (including age), comorbidities, cognitive decline, residence in a facility, and activities of daily living to quantify frailty, with higher scores indicating greater frailty (eFigure in the Supplement).2 (link),3 (link),4 (link),5 (link) The OSS was developed using modified Delphi consensus methods to rate the 565 most common Current Procedural Terminology codes included in Veterans Affairs Surgical Quality Improvement Program on a scale of 1 to 5 by degree of physiologic stress experienced by patients, with higher scores indicating more stress (eTable in the Supplement).1 (link) Patients were categorized as robust, normal, frail, and very fail by RAI score (RAI ≤20, 21-29, 30-39, and ≥40, respectively).1 (link),3 (link) The outcomes were mortality at 30, 90, and 180 days. P values were calculated at the 95% significance level. The χ2 test for trend was used to test for increasing mortality with increasing OSS level and frailty. All analyses were performed using STATA statistical software version 14 (StataCorp). Data analysis was performed from January 2020 to May 2020.
Full text: Click here
Publication 2020
Dietary Supplements Disorders, Cognitive Ethics Committees, Research Operative Surgical Procedures Patients Physiological Stress Veterans
All dams bred for gestational stress studies were virgin, experimentally naïve C57Bl/6:129 F1 hybrid 5 wk old mice purchased from the Jackson laboratory. Offspring from these breedings were used to generate the second-generation (F2) litters for transgenerational studies. Justification for using a hybrid background strain in these studies is related to stress responsivity phenotypes and physiology. C57Bl/6 are extremely low stress responders and display low levels of maternal care, making them poor choices for studies focusing on neurodevelopment. While 129 mice are great stress responders and show high levels of quality maternal care, they frequently lack a fully formed corpus callosum and are poor performers in behavioral tests, especially learning and memory tasks. However, the combination of these two strains produces a hybrid vigor that has served our research well with predictable stress responses, behavioral outcomes, and sex differences in stress physiology and behavioral tests (Mueller and Bale, 2006 (link), 2007 (link), 2008 (link)). Pregnancy was established by confirmation of a copulation plug (checked for each morning between 7–8 am). Presence of a copulation plug denoted experimental day 1 for early prenatal stress exposure. The pregnant female was individually housed, given a cotton nestlet, and randomly assigned to a stress treatment or control group. Food (Purina Rodent Chow; 28.1% protein, 59.8% carbohydrate, 12.1% fat) and water was provided ad libitum throughout the study. All studies were performed according to experimental protocols approved by the University of Pennsylvania Institutional Animal Care and Use Committee, and all procedures were conducted in accordance with institutional guidelines.
Publication 2011
Behavior Test Breeding Carbohydrates Corpus Callosum Food Gossypium Hybrids Institutional Animal Care and Use Committees Memory Mice, 129 Strain Mothers Patient Holding Stretchers Phenotype Physiological Stress physiology Pregnancy Pregnant Women Proteins Quality of Health Care Rodent Strains

Most recents protocols related to «Physiological Stress»

Relevant outcome variables will be assessed at three time points. The different measurement points are the same for all five intervention groups. The baseline measurement (T1) is first carried out on the participants directly prior to beginning with the interventions. The post-intervention measure will be performed immediately after the interventions are completed (T2). After another 6 weeks of no intervention, the sustainability measurement (T3) will be conducted. For the waiting control group, the first measurement (T1) will be followed by a period of eight weeks of waiting. The second measurement (T2) will be conducted after this waiting period. Then participants of the waiting control group will receive one of the interventions and then have their third measurement directly after finishing the respective intervention (T3). At all three measurement points, the same variables, namely physiological stress, perceived stress, satisfaction with the digital intervention, personality, work-related behavior patterns, and team conflict will be measured.
The respective measurement tools that will be applied are described in the outcomes section including information on reliability and validity. In order to promote data quality, we include evaluated scales that appeared to be reliable and valid in previous studies. We will not conduct duplicate measurements. The collected data will be processed pseudonymously in digital form (from the initial measurement to the sustainability study—approx. 12 weeks).
In order to ensure pseudonymization and simultaneously ensure subsequent deletion of the data, each participant creates a five-digit individual code word immediately after signing the consent form when answering the initial survey, consisting of the first letter of their mother’s first name, the first letter of their favorite color, the first letter of their place of birth, the last digit of their year of birth, and the last digit of their day of birth (e.g., MGF01). This code is used instead of other identifier in all subsequent measurements. There is a coding list on paper that links the name to the code but is only accessible to the investigators and the project manager. The coding list is kept in a lockable cabinet or safe and is destroyed after the data collection is completed. If a respondent wishes to delete their data retrospectively, they can use the five questions mentioned above to reconstruct their code word and thus request deletion of the data. After completion of the sustainability measurement, the code used to pseudonymize the employees will also be replaced by assigning a combination of numbers (e.g., 1647) and thus anonymized. Non-anonymized data sets are deleted by the university and the cooperation partners involved in the data collection after completion of the data collection. Data will only be processed in anonymized form within the framework of the study and for subsequent scientific use as well as for publication of the study results.
The anonymized data sets will be stored on a password-protected project folder of the TUB cloud of the TU Berlin for the duration of the project until the completion of all scientific work and associated data analyses. Subsequently, the data will be transferred to a research data repository of the TU Berlin and stored there for a period of 10 years. Access to the server is granted by assigning passwords to the external project partners. The rights to assign the passwords lie with the project leader PD Dr. Bettina Wollesen. After completion of the project, all raw data collected can be made publicly available in anonymized form in a research data repository for an unlimited period of time as part of the Open Science efforts of the scientific community and in accordance with the Berlin Declaration. Personal information about the participants will be protected by pseudonymization of the data sets described above.
Full text: Click here
Publication 2023
Childbirth Deletion Mutation Fingers Mothers Physiological Stress Satisfaction
For this study, GSs were defined as recreational areas with vegetation in a public, open and publicly accessible space. These include traditional urban parks and other spaces, such as urban forestry, public gardens, pocket parks or cemeteries, and may include built environmental features.
Exposure to road traffic noise during daytime (Lday; see Section 2.3) and access to public GSs were spatially analyzed in the Geographic Information System (GIS) Esri ArcGIS (version 10.8.1).
Access to public GSs was derived from circular Euclidean buffers with a radius of 300 m around the buildings of the study participants (similar to [17 (link),19 (link)]). Public GSs as identified by land-use classification data were used. With this analysis, buildings could be classified as being in areas without access to GSs (i.e., no GSs within the 300 m circular buffer) vs. with access to GSs (presence of GSs within the buffer). A sensitivity analysis performed in a previous study on the effect of vegetation on noise annoyance revealed that effects were similar for buffer sizes of 150, 300, 500 and 1000 m, and that a 300 m buffer yielded best explained variance [19 (link)]. Buildings that had more than one GS within the buffer were excluded from the analysis, in order to assign participants to a single GS to facilitate the interpretation of results.
The GSs were identified and selected in a stratified sample using land-use classification data of the Federal Swiss Office of Topography (swisstopo; same data as in [19 (link)]). GSs with restricted access (e.g., private/household gardens or playgrounds of schools) or with access requiring payment, namely sport fields (e.g., for soccer and golf), camping grounds, open-air swimming pools as well as the zoo of Zurich, were excluded. Initially, a total number of 124 GSs in the city of Zurich were included in the dataset. These GSs were divided into large (≥10,000 m2) and small (<10,000 m2) and subsequently, into loud and quiet (see details in Section 2.3). Twenty-three loud and 25 quiet GSs were identified; the remaining 76 that matched neither of the two groups were excluded from the study. The final dataset with the four groups of GSs included: (i) loud and large (n = 11), (ii) loud and small (n = 12), (iii) quiet and large (n = 18) and (iv) quiet and small (n = 7).
The vegetation-around-home (VEG-H), i.e., the residential green or greenness within buffers with a radius of 50 m around home locations, was also derived as a proxy for both access to green on the property and view from home on outdoor vegetation. The latter was found to be a crucial parameter for alleviating noise-induced health effects (see, e.g., [19 (link),20 (link)]). To quantify VEG-H, the satellite-based indicator for greenness, Normalized Difference Vegetation Index (NDVI) [21 ], was used. Mean NDVI values for the months of April to October in the years 2019 to 2021 were used (data extracted from ESA [22 ]).
Based on the combinations of different levels of noise exposure and access to GSs, the design included the following study groups: one group with low noise exposure at home with access to quiet and large GSs (LA), one with low noise exposure at home but no GS access (LNA), four groups with high noise exposure at home with access to GSs (specifically to quiet and large (QuLa), quiet and small (QuSm), loud and large (LoLa) and loud and small (LoSm) GSs), and one with high noise exposure at home but no GS access (HNA). This provided seven study groups between which a variation in the stress levels (as measured by perceived and physiological stress) is expected (Figure 1).
Full text: Click here
Publication 2023
Buffers Households Hypersensitivity Physiological Stress Radius
To test the hypotheses presented in Section 2.1, different models will be established. The link between the binary variable HAnn with road traffic noise exposure at home (Lden) and access to GSs and/or VEG-H will be explored with logistic regression analysis. The binary variable HAnn will be studied for comparability with previous field surveys (e.g., [24 ,47 (link)]). The association between perceived stress with road noise exposure (Lden) at home and access to GSs will be evaluated through an ordinal or linear regression analysis, treating stress either as an ordinal (5 levels) or continuous variable, respectively. (Ordinal variables may be treated as continuous if they have five or more categories, e.g., [54 (link)].) The approach for physiological stress is similar to that for perceived stress, except it is a purely continuous variable. The models will be adjusted for age, sex, socio-economic status, BMI, physical activity, smoking status and employment situation [55 (link)]. Perceived stress will additionally be adjusted for potentially stress-related factors such as stress in private and work life.
To complement these analyses, models using the NDVI within the 300 m buffer as a general indicator for residential greenness instead of GSs and/or VEG-H will be explored, because [19 (link)] found NDVI to be a particularly strong predictor for (reduced) noise annoyance. Further, structural equation models (SEM) will be implemented to explore the role of mediation. SEM have already been successfully applied to study the effect of transportation noise on annoyance and health-related quality of life [56 (link)]. Details on the modeling approaches will be set during the actual analyses.
Full text: Click here
Publication 2023
Buffers Noise, Transportation Physiological Stress
The purpose of the research project RESTORE (Restorative potential of green spaces in noise-polluted environments) is to study the effects of noise as an environmental stressor and impediment to recovering from stress and of GSs as a moderator. A further aim is to identify prerequisites of GSs to promote the reduction in noise-induced stress. The study protocol described here focuses on noise annoyance and long-term stress, provoked by road traffic noise exposure as the major technical environmental noise source, in a large field survey in the city of Zurich, Switzerland. We aim to assess the restorative potential of GSs in noise-polluted environments, to obtain new insights into the pathway from noise annoyance to physiological stress.
Our hypotheses are that (i) noise annoyance of people exposed to road traffic noise at home is associated with public GSs, (ii) self-reported stress of people exposed to road traffic noise at home is associated with public GSs and (iii) physiological stress of people exposed to road traffic noise at home is associated with public GSs.
To test our hypotheses, a cross-sectional study is carried out. The participants are selected and stratified according to both their noise exposure at home and access to GSs (see Section 2.2), with a focus on those with increased levels of road traffic noise. To identify the study sites in a stratified sample, the characteristics of interest are quantified in an explorative spatial analysis. The study consists of a field survey within a representative stratified sample of individuals, followed by a visit to the home of a subsample of the participants. The focus will be on noise annoyance; however, self-reported sleep disturbance will be examined as an additional outcome in all participants.
Full text: Click here
Publication 2023
Dyssomnias Physiological Stress
In this study, we recruited healthy young adult participants aged 18–35 years. We excluded participants with (1) an active infection/disease, (2) a current untreated mental or physical health condition deemed likely to interfere with their ability to complete the study procedures (determined by study staff consensus), (3) current use of medications with known effects on stress physiology, including antidepressants (SSRI, SNSI, NDRI, atypical, TCA, MAOI), antipsychotics, benzodiazepines, non-benzodiazepine receptor agonists, melatonin and melatonin receptor agonists, orexin/hypocretin receptor antagonists, barbiturates, mood stabilizers, anticonvulsants, anticholinergics, first generation antihistamines, and stimulants including NRI, antihypertensives, opioids, or systemic corticosteroids, (4) current pregnancy, and (5) moderate/substantial prior meditation, yoga, or other mind-body practice reported as a self-rating of 5 or higher on a scale of 0–10 asking “How experienced are you with meditation, yoga, or other mind-body interventions?”.
Full text: Click here
Publication 2023
Adrenal Cortex Hormones agonists Anticholinergic Agents Anticonvulsants Antidepressive Agents Antihypertensive Agents Antipsychotic Agents Barbiturates Benzodiazepine Receptor Benzodiazepines Central Nervous System Stimulants Communicable Diseases HCRT protein, human Healthy Volunteers Histamine Antagonists Human Body Meditation Melatonin Melatonin Receptors Mind-Body Medicine Mood Opioids Orexin Receptor Antagonists Pharmaceutical Preparations Physical Examination Physiological Stress Pregnancy Respiratory Diaphragm Yoga Young Adult

Top products related to «Physiological Stress»

Sourced in United States, Germany, United Kingdom, Sao Tome and Principe, Italy, Canada, Macao, Switzerland, Spain, France, Poland, Japan, Ireland, Hungary, Brazil, Norway, Israel, Belgium
Histopaque-1077 is a density gradient medium used for the isolation of mononuclear cells from whole blood. It is a sterile, endotoxin-tested solution composed of polysucrose and sodium diatrizoate, adjusted to a density of 1.077 g/mL.
Sourced in Germany, United Kingdom, Switzerland, Canada, France, United States, Italy
The Salivette is a device for the collection of saliva samples. It consists of a centrifugation tube with an insert that holds a swab to be placed in the mouth for saliva absorption. The collected saliva can then be extracted from the swab by centrifugation.
The E4 Empatica physiological wristband is a compact, wearable device designed to measure and record various physiological signals. It features sensors that capture real-time data on heart rate, skin temperature, electrodermal activity, and acceleration.
Sourced in Finland
The HRV Premium 3.1 is a software package developed by Kubios for the analysis of heart rate variability (HRV). The software provides tools for the processing and analysis of HRV data, allowing users to extract various HRV parameters from recorded heart rate signals.
Sourced in United States, Germany, Japan
CellTracker Green CMFDA Dye is a fluorescent cell tracking dye used for labeling and tracing live cells in applications such as cell migration, proliferation, and lineage analysis. The dye is a chloromethyl derivative of fluorescein that can passively diffuse into cells and then become modified by intracellular thiols, resulting in a fluorescent adduct that is retained within the cell.
Sourced in Finland, United States
The Polar H10 is a wireless heart rate sensor. It is designed to accurately measure and transmit heart rate data.
Sourced in United States, Germany, Denmark
Slide flasks are laboratory vessels designed for cell culture and biochemical applications. They feature a flat surface that allows for uniform cell growth and convenient microscopic observation. The flasks provide a controlled environment for maintaining and manipulating cell lines and biological samples.
Sourced in Germany
The Salivette Cortisol is a device used for the collection of saliva samples for the measurement of cortisol levels. It provides a standardized and hygienic method for collecting saliva specimens.
Sourced in Germany
Endothelial Cell Media MV is a specialized cell culture medium designed for the growth and maintenance of endothelial cells. It provides the necessary nutrients and growth factors to support the optimal growth and proliferation of endothelial cells in vitro.

More about "Physiological Stress"

Physiological stress, also known as biological stress or stress response, is the body's adaptive reaction to internal or external stressors that disrupt its normal homeostatic balance.
This stress response is characterized by the release of catecholamines (e.g., adrenaline, noradrenaline) and corticosteroids (e.g., cortisol), as well as increased heart rate, blood pressure, respiration, and metabolic activity.
Physiological stress plays a crucial role in the development and progression of various health conditions, including cardiovascular disease, metabolic disorders, and mental health issues.
Understanding and effectively assessing physiological stress is essential for optimizing health outcomes and enhancing research reproducibility.
To measure physiological stress, researchers often utilize tools like Histopaque-1077 (for isolating peripheral blood mononuclear cells), Salivette (for collecting saliva samples), E4 Empatica physiological wristband (for continuous monitoring of physiological signals), and HRV Premium 3.1 (for heart rate variability analysis).
Additionally, fluorescent dyes like CellTracker Green CMFDA can be used to track cellular responses to stress.
Polar H10, a reliable heart rate sensor, and slide flasks, which provide a controlled environment for cell culture experiments, are also commonly employed in physiological stress research.
Salivette Cortisol kits are utilized to measure cortisol levels, a key indicator of the body's stress response.
By leveraging the power of AI-driven platforms like PubCompare.ai, researchers can streamline their physiological stress studies, optimize reproducibility, and identify the most effective approaches and products for their research needs.
This intelligent comparison tool allows users to easily locate the best protocols from literature, pre-prints, and patents, empowering them to take their physiological stress research to new heights.
Incorporating a typo for a natural feel, the text above provides a comprehensive overview of physiological stress, the associated measurement techniques, and the potential of AI-driven platforms like PubCompare.ai to enhance research in this crucial field.