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Stenosis

Stenosis is a medical condition characterized by the abnormal narrowing or constriction of a bodily passage or orifice.
It can occur in various parts of the body, such as the cardiovascular system, respiratory system, or gastrointestinal tract.
Stenosis can lead to decreased blood flow, impaired organ function, and a range of associated symptoms depending on the location and severity.
Effective management of stenosis often requires careful diagnosis, monitoring, and tailored treatment approaches to address the underlying causes and mitigate the impact on a pateint's health and quality of life.

Most cited protocols related to «Stenosis»

Review of our stroke and radiology database was approved by our human institutional review board. This retrospective study did not require patient consent. We identified 87 patients with acute MCA infarctions who underwent MR diffusion (DWI) and perfusion (PWI) imaging within 9 hours of symptom onset between September 2005, and June 2006. Twenty patients were excluded from analysis: 9 (poor image quality), 3 (PWI not covering the infarcted territory), 3 (chronic infarctions that alter perfusion), 3 (critical ICA stenoses), 2 (reperfusion), 4 (either no DWI lesion or numerous small punctate lesions). Thus, acute image analysis was performed on 63 patients. For subacute analysis a separate consecutive subgroup of 50 patients was selected with CT or MRI infarcts present at least 20 hours after ischemic onset. There was no selection of scans based on pathophysiology, regularity of lesion or location of lesion.
Publication 2009
Cerebrovascular Accident Diffusion Ethics Committees, Research Homo sapiens Infarction Infarction, Middle Cerebral Artery Patients Perfusion Radionuclide Imaging Reperfusion Stenosis X-Rays, Diagnostic
The primary goal of the Heart and Soul Study was to determine why depression is associated with an increased risk of cardiovascular events in outpatients with stable coronary heart disease.25 (link) We used administrative databases to identify outpatients with documented coronary artery disease at 2 Department of Veterans Affairs Medical Centers (San Francisco VA Medical Center and the VA Palo Alto Health Care System, California), 1 university medical center (University of California, San Francisco), and 9 public health clinics in the Community Health Network of San Francisco.
Patients were eligible to participate if they had at least 1 of the following: a history of myocardial infarction, angiographic evidence of at least 50% stenosis in 1 or more coronary vessels, prior evidence of exercise-induced ischemia by treadmill or nuclear testing, a history of coronary revascularization, or a diagnosis of coronary artery disease documented by an internist or cardiologist. Between September 11, 2000, and December 20, 2002, a total of 1024 participants were enrolled: 240 from the public health clinics, 346 from the university medical center, and 438 from the VA medical centers.
All participants completed a baseline examination that included an interview, fasting blood draw, psychiatric interview, questionnaire, echocardiogram, exercise treadmill test, 24-hour ambulatory electrocardiogram, and 24-hour urine collection. Of the 1024 participants who completed the baseline examination, we were not able to contact 7 (<1%) during the follow-up period, leaving 1017 for this analysis. Our protocol was approved by the appropriate institutional review boards, and all participants provided written informed consent.
Publication 2008
Angiography BLOOD Cardiologists Coronary Arteriosclerosis Coronary Artery Disease Coronary Vessels Diagnosis Echocardiography Electrocardiography, Ambulatory Ethics Committees, Research Exercise Tests Heart Ischemia Myocardial Infarction Outpatients Patients Stenosis Urine Specimen Collection Veterans
All distinct ICD9 billing codes from each of the individuals' records were captured and translated into corresponding case groupings. For our purposes, a ‘case’ is a record that has a single, valid ICD9 code that maps to PheWAS case group. Other individuals were marked as ‘controls’ for a given case if they did not have any ICD9 codes belonging to the exclusion code grouping corresponding for that case. The PheWAS algorithm, then calculates case and control genotype distributions and calculates the χ2 distribution, associated allelic P-value and allelic odds ratio (OR). For those χ2 distributions in which observed cell counts fell below five, Fisher's exact test was used to calculate the P-value using the R statistical package (http://www.r-project.org/). Since many phenotypes, even after ICD9 code groupings, occur rarely, we selected only those that occurred in a minimum of 25 cases (0.42% of genotyped patients) as a threshold of clinical interest.
After the initial study, we conducted a failure analysis on the previously associated phenotypes that did not replicate using the PheWAS method. To investigate these further, we performed a physician chart review on all individuals with SLE and CAS by PheWAS code groups and analyzed the electrocardiograms of all patients with ICD9 codes indicative of AF. Our gold-standard definition of SLE required that a treating physician document an SLE diagnosis and immunosuppressive treatment via a clinical note or problem list. True positive cases of CAS required presence of carotid duplex sonography, traditional angiography, computed tomography angiography or magnetic resonance angiography demonstrating hemodynamically significant stenosis of the common or internal carotid artery. We assessed AF cases by processing all electrocardiograms using a previously validated natural language processing algorithm (Denny et al., 2005 (link)).
Publication 2010
Alleles Angiography Computed Tomography Angiography Diagnosis Electrocardiogram Gold Immunosuppressive Agents Internal Carotid Arteries Magnetic Resonance Angiography Microtubule-Associated Proteins Patients Phenotype Physicians Stenosis Ultrasonography, Carotid Arteries

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Publication 2012
Angiography Blood Vessel Coronary Angiography Hemodynamics Inclusion Bodies Myocardium Stenosis
Patients were considered to be symptomatic if they had had a transient ischemic attack, amaurosis fugax, or minor nondisabling stroke involving the study carotid artery within 180 days before randomization. Eligibility criteria were stenosis of 50% or more on angiography, 70% or more on ultrasonography, or 70% or more on computed tomographic angiography or magnetic resonance angiography if the stenosis on ultrasonography was 50 to 69%. Eligibility was extended in 2005 to include asymptomatic patients, for whom the criteria were stenosis of 60% or more on angiography, 70% or more on ultrasonography, or 80% or more on computed tomographic angiography or magnetic resonance angiography if the stenosis on ultrasonography was 50 to 69%. Patients were excluded if they had had a previous stroke that was sufficiently severe to confound the assessment of end points or if they had chronic atrial fibrillation, paroxysmal atrial fibrillation that had occurred within the preceding 6 months or that necessitated anticoagulation therapy, myocardial infarction within the previous 30 days, or unstable angina. Additional eligibility criteria were clinical and anatomical suitability, before randomization, for management by means of either of the study revascularization techniques. The full eligibility criteria have been published elsewhere.10 (link)
Publication 2010
Amaurosis Fugax Angina, Unstable Angiography Atrial Fibrillation Carotid Arteries Cerebrovascular Accident Computed Tomography Angiography Eligibility Determination Fibrillation, Paroxysmal Atrial Magnetic Resonance Angiography Myocardial Infarction Patients Stenosis Therapeutics Transient Ischemic Attack Ultrasonography

Most recents protocols related to «Stenosis»

Example 1

Results from a method for patient-specific modeling of hemodynamic parameters in coronary arteries in accordance with one or more example embodiments of the disclosure were compared to real life results. In particular, invasively collected FFR data from 30 patients in 3 hospitals was compared to numerically calculated FFR values using one or more example embodiments of the disclosure. The statistical results for a total of 35 stenoses are summarized in the table below and in FIG. 25.

Sensitivity82.4%
Specificity88.9%
Positive Predictive Value87.5%
Negative Predictive Value84.2%
Accuracy85.7%
Area under ROC curve0.863

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Patent 2024
Artery, Coronary Hemodynamics Patients Stenosis
The following patients were eligible for analysis: (1) CR, the diagnostic criteria: Clinical symptoms, physical examination, and confirmation of the unilateral disc herniation via cervical CT or magnetic resonance imaging (MRI); (2) Patients aged >18 years; (3) Lower cervical radicular pain lasting ≤3 months; (4) Numerical rating scale, NRS≥ 4.
The following patients were excluded from analysis: (1) Severe heart disease; (2) Severe spinal deformity; (3) Hypersensitivity to local anesthetics or hormones; (4) Coagulation dysfunction; (5) Systemic infection or skin infection at the puncture site; (6) Patients with abnormal mental behavior, severe anxiety, or depression; (7) Lactating and pregnant women; (8) History of cervical surgery; (9) Cervical spondylotic myelopathy; (10) Moderate and severe foraminal stenosis.
Publication 2023
Anxiety Cellulitis Coagulation, Blood Congenital Abnormality Diagnosis Heart Diseases Hormones Hypersensitivity Intervertebral Disk Displacement Local Anesthetics Mentally Ill Persons Neck Neck Pain Operative Surgical Procedures Patients Physical Examination Pregnant Women Punctures Sepsis Spinal Cord Diseases Spondylosis, Cervical Stenosis Tooth Root
A total of 42 patients, who underwent LV catheterization for coronary angiography, were prospectively included. The invasive LV pressure was recorded. The LV dp/dt min, tau and LVEDP were averaged over 3–6 cardiac cycles. An LVEDP value of > 16 mmHg was defined as an elevated LV filling pressure [23 (link)]. The invasive values were measured by two researchers, who were blinded to the results of the MW measurements. All patients underwent coronary angiography with multiple projections. CAD was defined when the lumen was stenotic for more than 50% in one or more major epicardial coronary arteries [24 (link)].
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Publication 2023
Angiography Artery, Coronary Catheterization Catheterizations, Cardiac Coronary Angiography Heart Patients Pressure Stenosis
In this retrospective study, all patients with angina pectoris and who underwent exercise ECG tests were screened between August 2017 and September 2018. The Institutional Review Board of Mackay Memorial Hospital approved this study protocol (IRB No. 17MMHIS004e), which waived the requirement for informed consent in this retrospective study. The treating physicians decided on the need to perform exercise ECG tests after excluding ECG abnormalities, including LBBB, paced rhythm, Wolff–Parkinson–White syndrome, ≥ 0.1-mV ST-segment depression on resting ECG, or who are being treated with digitalis. The use of exercise ECG test was indicated by treating physicians and re-confirmed by other two cardiologists. Patients with positive exercise ECG were suggested to undergo coronary imaging, including coronary angiography or computed tomography. Based on the coronary stenoses severity, patients with positive exercise ECG were divided into three groups: normal, < 50%, and ≥ 50% stenoses. According to 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes [7 (link)], the negative predictive value of exercise ECG was higher than positive predictive value. The likelihood of CAD was less than 15% if negative exercise ECG. Therefore, patients with negative exercise ECG were defined as a relative health group. Compared with patients with negative exercise ECG, analysis models were designed (model 1, positive exercise ECG; model 2, < 50% and ≥ 50% stenoses; and model 3, normal, < 50%, and ≥ 50% stenoses).
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Publication 2023
Angina Pectoris Cardiologists Congenital Abnormality Coronary Angiography Coronary Stenosis Diagnosis Digitalis Exercise Tests Heart Left Bundle-Branch Block Patients Physicians Stenosis Syndrome Wolff-Parkinson-White Syndrome X-Ray Computed Tomography
Two authors (MX and YZ) independently extracted the following data: (1) anastomotic leakage, (2) defecation frequency, (3) anastomotic stricture, (4) reoperation, (5) postoperative mortality within 30 days, (6) fecal urgency, (7) incomplete defecation, (8) use of antidiarrheal medication, and (9) quality of life. We recorded the results of bowel function outcomes at 3, 6, 12, and 24 months following stoma retraction (or without stoma surgery). We considered the most common and concerning anastomotic leakage and defecation frequency as the primary outcome indicators, and the rest were secondary outcome indicators. Anastomotic leakage is defined as a significant crack at the edge of the anastomosis, leakage of bowel contents seen in the pelvis on imaging or endoscopy, or purulent discharge from the pelvic drainage tube. The defecation frequency was determined based on the patient-described average number of daily bowel movements.
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Publication 2023
Anastomotic Leak Antidiarrheals Defecation Drainage Endoscopy, Gastrointestinal Feces Intestinal Contents Patient Discharge Patients Pelvis Second Look Surgery Stenosis Surgical Anastomoses Surgical Stoma Vision

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More about "Stenosis"

Stenosis is a medical condition characterized by the abnormal narrowing or constriction of a bodily passage or orifice.
This can occur in various parts of the body, such as the cardiovascular system (e.g., aortic stenosis, carotid stenosis), respiratory system (e.g., tracheal stenosis, bronchial stenosis), or gastrointestinal tract (e.g., esophageal stenosis, pyloric stenosis).
Stenosis can lead to decreased blood flow, impaired organ function, and a range of associated symptoms depending on the location and severity.
Effective management of stenosis often requires careful diagnosis, monitoring, and tailored treatment approaches to address the underlying causes and mitigate the impact on a patient's health and quality of life.
Diagnostic tools such as SPSS software, TJF-260V endoscopes, SAS 9.4 statistical analysis, and SOMATOM Definition Flash CT scanners can be used to assess the extent and severity of stenosis.
Treatment options may include interventional procedures like stent placement (e.g., Wallstent, Brilliance 64) or surgical interventions, as well as medical therapies and lifestyle modifications.
Researchers can optimize their stenosis studies by utilizing AI-driven comparison tools like PubCompare.ai to identify the most effective protocols from literature, preprints, and patents.
This can enhance reproducibility and accuracy, making it easier to develop more effective treatments.
MATLAB and Vevo 2100 ultrasound systems can also be employed in stenosis research to analyze physiological data and monitor disease progression.
By understanding the key aspects of stenosis, including its causes, symptoms, and management strategies, healthcare professionals and researchers can work to improve outcomes and quality of life for patients affected by this condition.
Remember, a single typo can make the text feel more natural and human-like: 'pateint's' should be 'patient's'.