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Venous Thrombosis

Venous thrombosis is a serious medical condition where a blood clot forms in a vein, often in the leg or pelvis.
This can lead to complications like swelling, pain, and potentially life-threatening pulmonary embolism if the clot travels to the lungs.
Accurate diagnosis and effective treatment are crucial for managing venous thrombosis and preventing long-term consequences.
Researchers can leverage PubCompare.ai's AI-driven platform to streamline their studies, locate the best protocols, and identify the most effective approaches, enhancing reproducability and research accuracy in this important field of medicine.

Most cited protocols related to «Venous Thrombosis»

The baseline questionnaire (Q_0) included 554 questions about a wide array of characteristics: socio-demographic (e.g. sex, age and marital status), anthropometric (e.g. weight and height, weight gain in the past five years), lifestyle and health-related habits (e.g. smoking status, physical activity), diet (e.g. energy and alcohol intakes), employment status (e.g. employed/unemployed and working hours/week), obstetric history for women (e.g. pregnancy) and medical history (e.g. prevalence of chronic diseases and medication use). Total energy and alcohol intakes were ascertained through a semi-quantitative food frequency questionnaire (136 food items) previously validated in Spain [26 (link)]. Physical activity was collected through a validated questionnaire that included information about 17 activities such as walking, running, cycling, swimming, judo, soccer, skiing or sailing. To quantify the volume of activity during leisure time, an activity metabolic equivalent (MET) index was computed by assigning a multiple of resting metabolic rate (MET score) to each activity [27 (link)], and the time spent in each of the activities was multiplied by the MET score specific to each activity, and then summed the overall activities obtaining a value of overall weekly MET-hours. Leisure time physical activity estimated with the questionnaire was previously validated by our group using a tri-axial accelerometer as the gold standard. Physical activity during leisure time (estimated as MET-h/week) derived from the questionnaire moderately correlated with Kcal/day assessed through the accelerometer (Spearman's rho = 0.507, 95% CI: 0.232 – 0.707, p < 0.001) [28 (link)].
Participants were classified as having cardiovascular disease at baseline or at follow-up if they reported at least one of the following conditions: myocardial infarction, stroke, atrial fibrillation, paroxysmal tachycardia, coronary artery bypass grafting or other revascularization procedures, heart failure, aortic aneurism, pulmonary embolism, or peripheral venous thrombosis. Information regarding cancer both at baseline and during follow-up was also collected.
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Publication 2009
Aortic Aneurysm Atrial Fibrillation Cardiovascular Diseases Cerebrovascular Accident Congestive Heart Failure Diet Disease, Chronic Food Gold Malignant Neoplasms Metabolic Equivalent Myocardial Infarction Pharmaceutical Preparations Physical Examination Pregnancy Pulmonary Embolism Resting Metabolic Rate Tachycardia, Paroxysmal Venous Thrombosis Woman
This model provides a total stasis environment and results in the most severe vein wall reaction to thrombosis of the models discussed.8 (link),17 (link),20 (link),23 Studies in rats suggest that after IVC ligation a combination of stasis-induced vein wall injury and enhanced tissue factor expression in endothelial cells and leukocytes produce thrombosis.42 (link) In this model, mice are anesthetized and a midline laparotomy is performed. The small bowel is exteriorized and placed on a moistened gauze pad to the animal’s left. The infrarenal IVC is identified and all side branches are ligated with nonreactive 7-0 Prolene suture. Posterior venous branches are cauterized.23 A 7-0 Prolene suture is tied down on the IVC, caudal to the left renal vein. This model has been widely used by our group for the study of venous thrombosis.8 (link),17 (link),20 (link),21 (link) It provides reproducible thrombus weights beginning at 3 hours and extending to 21 days, for most mouse strains. It has proven valuable in the study of interactions between the vein wall and thrombus during the progression from acute to chronic inflammation and remodeling of the vein wall. Disadvantages include the lack of blood flow. A technical pitfall unique to this procedure is the potential to induce initial hypotension. However, compensation by vertebral veins is observed and the survival rate for this model is around 95%, based on our laboratory’s observations. In addition, the IVC cannot reopen because of the ligature. This model cannot reproduce the clinical scenario where a thrombus is nonocclusive, but it can mimic complete occlusion (Figure 2 and Table). As a guideline, data from our laboratories in C57BL/6 mice shows, approximate thrombus weights (IVC+thrombus at harvest), of 33 mg at day 2, 29 mg at day 6, and 18 mg at day 14.
Publication 2012
Animals Blood Circulation Dental Occlusion Disease Progression Endothelial Cells Inflammation Injuries Intestines, Small Laparotomy Leukocytes Ligation Ligature Mice, Inbred C57BL Mus Prolene Rattus norvegicus Strains Sutures Thromboplastin Thrombosis Thrombus Vein, Renal Veins Venous Thrombosis Vertebra
At each participating site, patients are screened by the site investigators and checked for eligibility (Table 1). All patients with objectively confirmed acute symptomatic or asymptomatic VTE (i.e. DVT, PE, or both). More recently, in an attempt to similarly understand the presentation, treatment pattern, and outcomes of other thrombotic conditions, RIETE has also started to enroll patients with superficial vein thrombosis, splanchnic vein thrombosis (i.e. thrombosis involves the mesenteric, splenic, or portal veins), retinal vein thrombosis, and cerebral vein thrombosis. At each participating center, every attempt is made to enroll consecutive patients and RIETE investigators are committed, by contract agreement, to enroll consecutive patients. Periodic audits of the sites have confirmed consecutiveness. Further, comparison against the Spanish Ministry of Health database has shown that patients in RIETE have similar characteristics to the data from all-comers with VTE in that database.(28 (link)) No duplicate entries are permitted and patients who are enrolled in blinded treatment trials are ineligible.
Methods of DVT diagnosis include contrast venography, ultrasonography, magnetic resonance, or rarely in the past, plethysmography (only 172 patients in the entire cohort). PE is diagnosed on the basis of pulmonary angiography, contrast-enhanced computed tomography (CT) of the chest (specifically CT pulmonary angiography), lung scintigraphy, or rarely on the basis of confirmed DVT in patients with signs and symptoms of PE.
RIETE, by design, does not currently enroll patients with intracardiac thrombi in the absence of VTE. As of June 30, 2017, a total of 72,107 valid patients with acute VTE have been enrolled in RIETE. Currently, RIETE has 179 participating sites from 24 countries and across 3 continents. There has been a growth, over time, in the number of involved sites and countries (Figure 2, Panels A and B).
Publication 2018
Angiography Cerebral Thrombosis Cerebral Vein Chest Computed Tomography Angiography Eligibility Determination Hispanic or Latino Lung Magnetic Resonance Imaging Mesentery Patients Phlebography Plethysmography Radionuclide Imaging Retinal Vein Thromboses Spleen Thrombosis Thrombus Ultrasonography Veins Veins, Portal Venous Thrombosis X-Ray Computed Tomography
This retrospective analysis was approved by the Institutional Review Board at BCH. The clinical imaging database at BCH was retrospectively reviewed for this analysis from 01 January 2008 until 24 February 2016. All MRI examinations that included brain imaging of participants aged 0–32 years at the time of imaging were included for further analysis. Examinations deemed to be of low quality (because of excessive participant motion, large metal artefact from a subject’s dental hardware, lack of a T1 structural imaging volume providing diagnostically useful axial, sagittal, and coronal oriented images, etc.) were excluded from the study. Examinations and medical records that were inaccessible because of technical reasons were excluded. Healthy subjects were retrospectively identified from routine clinical imaging by including subjects with a normal MRI examination as assessed by a BCH radiologist and whose medical records provide no indication of any substantive neurological problems (subjects with any known neurodevelopmental disorder were excluded such as autism, cerebral palsy, attention deficit hyperactivity disorder, epilepsy, neurofibromatosis, developmental delay, tuberous sclerosis complex, hemiplegia, hallucinations, any brain tumor, bipolar disorder, obsessive compulsive disorder, abnormal psychological factors, meningitis, encephalopathy, postconcussion syndrome, learning disabilities, abnormal EEG examination, paresthesia, Bardet–Biedl syndrome, Waardenburg syndrome, cerebral venous thrombosis, demyelination, etc.). Participants with any type of cancer (including outside the central nervous system) were excluded to avoid neurological data with altered growth trajectories caused by common treatments such as chemotherapy. This yielded 993 examinations (395 male, 598 female) from 988 participants. A joint histogram demonstrating the age distributions for both the male and female healthy participants are provided in Figure 1.
Publication 2017
Autistic Disorder Bardet-Biedl Syndrome Bipolar Disorder Brain Brain Neoplasms Central Nervous System Cerebral Palsy Cerebral Thrombosis Cerebral Vein Demyelination Dental Equipment Disorder, Attention Deficit-Hyperactivity Encephalopathies Epilepsy Ethics Committees, Research Hallucinations Healthy Volunteers Hemiplegia Joints Learning Disabilities Males Malignant Neoplasms Meningitis Metals Neurodevelopmental Disorders nf1 Gene Obsessive-Compulsive Disorder Paresthesia Pharmacotherapy Physical Examination Post-Concussion Syndrome Psychological Factors Radiologist Thrombosis Tuberous Sclerosis Veins Venous Thrombosis Waardenburg Syndrome Woman
Mice were anesthetized by intraperitoneal injection as described previously (Massberg et al., 2002 (link)). A median laparotomy was performed and the IVC was exposed by atraumatic surgery. We positioned a space holder (FloppyR II Guide Wire 0.014 in [0.36 mm]; Guidant Corporation) on the outside of the vessel and we placed a permanent narrowing ligature (8.0 monofil polypropylene filament, Premilene; Braun) exactly below the left renal vein. Subsequently, the wire was removed to avoid complete vessel occlusion. Side branches were not ligated or manipulated. Flow velocity was determined immediately after the flow restriction (Cap-Image 7.1). Because we wanted to rule out endothelial injury as a trigger for venous thrombosis, all mice with bleedings or any injury of the IVC during surgery were excluded from further analysis. There was no difference in the exclusion rate across the different experimental groups. After the procedure, a subset of animals was investigated by intravital microscopy. In the remainder, the median laparotomy was immediately sutured by a 7.0 polypropylene suture (Ethicon). For weight measurement, the vessel was excised just below the renal veins and proximal to the confluence of the common iliac veins. After the restriction procedure the blood flow velocity was reduced by ∼80% (Fig. 1 B). The shear stress was 0.144 dyne/cm2 ± 0.02 SEM before the flow restriction and 0.072 dyne/cm2 ± 0.017 SEM after the procedure in the IVC close to the site of ligation. Sham experiments consisted of preparation of the IVC and placement of the filament under the vessel without ligation.
Publication 2012
Animals Blood Flow Velocity Blood Vessel Cytoskeletal Filaments Dental Occlusion Endothelium Hemorrhage Iliac Vein Injections, Intraperitoneal Injuries Intravital Microscopy Laparotomy Ligation Ligature Mice, House Operative Surgical Procedures Polypropylenes Precipitating Factors Sutures TRAF3 protein, human Vein, Renal Venous Thrombosis

Most recents protocols related to «Venous Thrombosis»

The inclusion criteria for this meta-analysis were as follows: Study design: randomized controlled trials (RCTs) comparing the effects of quantified versus willful grip exercises in PICC patients; Research population: patients with indwelling PICCs; Interventions: the experimental group underwent quantified grip exercises by designed nursing care plans, the control group underwent grip exercises at their own willingness; Observation indicators: The main indicators are the incidence of venous thrombosis and venous hemodynamics, and the secondary indicators are the infection rate associated to PICC. Venous thrombosis and venous blood flow velocity were examined with Doppler color ultrasound. The maximum venous blood flow velocity refers to the maximum blood flow velocity per second in the blood vessel. The exclusion criteria for this meta-analysis were: Replicated publications; Literature reports for which the full-text could not be obtained or the data could not be extracted.
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Publication 2023
Blood Flow Velocity Blood Vessel Grasp Hemodynamics Infection Nursing Care Plans Patients Ultrasounds, Doppler Veins Venous Thrombosis Volition
The 2 researchers searched the associated studies by combinations of search terms and keywords. The search terms used in this meta-analysis were as follows: (“fist exercise” OR “ball-holding sport” OR “handgrip exercise” OR “quantitative physical intervention” OR “functional exercise”) AND (“PICC” OR “peripherally inserted central catheter” OR “PICC-related VT” OR “venous thrombosis” OR “catheter-related thrombosis.” Databases searched in this meta-analysis included PubMed, CINAHL and Cochrane Library, China Biomedical Literature Database, China national knowledge infrastructure, Wanfang and Weipu databases. The retrieval limit was from the establishment of the database to August 31, 2022.
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Publication 2023
Catheters cDNA Library Physical Examination Thrombosis Venous Thrombosis

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Publication 2023
Anemia Asthma Atrial Fibrillation Cardiac Arrhythmia Cardiomyopathies Cardiovascular Diseases Cerebrovascular Accident Chronic Obstructive Airway Disease Congestive Heart Failure Deep Vein Thrombosis Dementia Disease, Chronic Gout Hemorrhage Index, Body Mass Lipid Metabolism Disorders Malignant Neoplasms Myocardial Infarction Obesity Pulmonary Embolism Subarachnoid Hemorrhage Transient Ischemic Attack Venous Thrombosis
Details on on-site ICU physician coverage, the Tele-ICU staffing, and daily tasks of the Tele-ICU team are showed in Fig. 1. The Tele-ICU system (eCareManager® 4.1, Philips, U.S.A) used in the study supports the decision-making process by patient information centralization and real-time physiological severity evaluation based on automatic analysis (Fig. 2). The Tele-ICU staff consists of a board-certified intensivist, specially trained nurses, and a clerical assistant to the doctor. One nurse is responsible for up to 50 patients. A support center nurse is stationed 24/7. Daily Tele-ICU team tasks involve communication with on-site staff and patients using a secured audio–video system on demand and proactive survey of high risk or physiologically worsening patients to prevent unfavorable events. Venous thrombosis prophylaxis, stress ulcer prophylaxis, medication dosing appropriateness such as catecholamines, vasopressor, analgesics and sedatives, recommendation of early mobilization, early enteral feeding, and sepsis management were included in the tasks. Because the role of Tele-ICU is severity evaluation and advice in this study, the Tele-ICU physicians do not order instead of the on-site physician and only record the contents of the consultation. In addition, as the Tele-ICU physicians expertise in respiratory care and lung protective ventilation, they performed scheduled and/or on demand respiratory round. Tele-ICU physicians are given full authority of bed placement and transfer in university hospital ICU.

Details on on-site ICU physician coverage, the Tele-ICU staffing, and daily tasks of the Tele-ICU of Showa University Hospital

Outlines of the Tele-ICU system used in the study. BGA blood gas analysis, GCS Glasgow Coma Scale, RASS Richmond agitation–sedation scale, ICDSC Intensive Care Delirium Screening Checklist, CAM–ICU Confusion Assessment Method for the ICU, NMBA neuromuscular blocking agent, ECMO extracorporeal membrane oxygenation, IABP intra-aortic balloon pumping, VAD ventricular assist device, RRT renal replacement therapy

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Publication 2023
Analgesics Artificial Ventricle Blood Gas Analysis Catecholamines Clergy Delirium Early Mobilization Extracorporeal Membrane Oxygenation Intensive Care Neuromuscular Blocking Agents Nurses Patients Pharmaceutical Preparations Physicians physiology ras Oncogene Renal Replacement Therapy Respiratory Rate Sedatives Septicemia Tele-Intensive Care Ulcer Vasoconstrictor Agents Venous Thrombosis
PSC is progressive biliary fibrosis affecting intra and/or extrahepatic bile ducts[12 (link)] and diagnosed by laboratory tests [(cholestasis, Antineutrophil cytoplasmic antibodies (ANCA)], radiology [abdominal ultrasonography (US), abdominal computed tomography (CT), endoscopic retrograde cholangiopancreatography (ERCP), or magnetic resonance cholangiopancreatography (MRCP)], and liver biopsy. Primary biliary cholangitis (PBC) is characterized by the loss of small and medium-sized bile ducts on liver biopsy, elevated anti-mitochondrial antibodies, and altered gamma-glutamyl transferase and alkaline phosphatase (ALP) levels[13 (link)]. Non-alcoholic fatty liver disease (NAFLD) is characterized by fat storage in ≥ 5% of hepatic steatosis in the absence of concomitant liver disease (chronic viral hepatitis), use of steatosis-inducing medications (amiodarone or tamoxifen), autoimmune hepatitis, hemochromatosis, Wilson's disease, or excessive alcohol consumption[14 (link)]. Diagnosis of NAFLD was made by liver biopsies or US[15 (link)], and the severity score was previously stated[16 (link)]. Autoimmune hepatitis diagnosis based on the International Autoimmune Hepatitis Group criteria with a score of > 15 points consisting of demographic, histologic, and laboratory markers, including antinuclear antibodies with a titer of at least 1:40 and liver histology[17 (link)]. An aseptic liver abscess is diagnosed based on IBD history, US, and CT[18 (link)]. Ultrasound, colour Doppler, and/or CT scans were used to detect portal vein thrombosis.
Publication 2023
Abdomen Alkaline Phosphatase Amiodarone Anti-Antibodies Antibodies, Antinuclear Antineutrophil Cytoplasmic Antibodies Asepsis Autoimmune Chronic Hepatitis Bile Bile Ducts, Extrahepatic Biopsy Cholangiopancreatography, Magnetic Resonance Cholestasis Duct, Bile Endoscopic Retrograde Cholangiopancreatography Fatty Liver Fibrosis gamma-Glutamyl Transpeptidase Hemochromatosis Hepatic Duct Hepatitis, Chronic Hepatolenticular Degeneration Liver Liver Abscess Liver Diseases Mitochondria Non-alcoholic Fatty Liver Disease Pharmaceutical Preparations Primary Biliary Cholangitis Radiography Radionuclide Imaging Steatohepatitis Tamoxifen Thrombosis Ultrasonography Veins, Portal Venous Thrombosis X-Ray Computed Tomography

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More about "Venous Thrombosis"

Venous thrombosis, also known as deep vein thrombosis (DVT), is a serious medical condition where a blood clot (thrombus) forms in a vein, often in the leg or pelvis.
This can lead to complications such as swelling, pain, and potentially life-threatening pulmonary embolism if the clot travels to the lungs.
Accurate diagnosis and effective treatment are crucial for managing venous thrombosis and preventing long-term consequences.
Researchers can leverage PubCompare.ai's AI-driven platform to streamline their studies on venous thrombosis.
The platform helps researchers locate the best protocols from literature, preprints, and patents, using AI-driven comparisons to identify the most effective approaches.
This can enhance the reproducibility and accuracy of research in this important field of medicine.
PubCompare.ai's platform can assist researchers in various ways, such as: - Identifying the most relevant and reliable protocols for diagnosing and treating venous thrombosis, including techniques like Lipiodol, SAS version 9.4, SAS v9.4, C57BL/6 mice, SPSS Statistics, Vivid 7 Dimension'06, SAS 9.4, Acuson S2000, and Aquilion ONE. - Comparing the effectiveness of different approaches and interventions to manage venous thrombosis, enabling researchers to make informed decisions and optimize their research. - Enhancing the reproducibility of studies by providing a standardized and AI-driven platform for protocol selection and comparison. - Improving the overall accuracy and reliability of research on venous thrombosis, leading to better treatment outcomes and patient care.
By utilizing PubCompare.ai's AI-driven platform, researchers can streamline their studies, locate the best protocols, and identify the most effective approaches, ultimately enhancing the reproducibility and accuracy of their research in the field of venous thrombosis.