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Example 2
Five subjects (males, ages 34 to 52 years old) each with a respiratory illness and having SpO2 less than 92% were administered a composition comprising 1200 mg of potassium nitrate, 200 mg of elemental magnesium, 50 mg of elemental zinc in one capsule, co-administered with another capsule containing 1000 mg of citric acid. Their blood oxygen saturation level was measured between 15 to 80 minutes after ingestion of the composition. Their symptoms related to the respiratory illness were also recorded before and after ingestion of the composition. Table 2 summarizes the results.
The flow of participants enrollment and PTB detection model construction and test
Demographic characteristics of participants
Discovery data set | Test data set | |||||
---|---|---|---|---|---|---|
PTB (N = 361) | Control (N = 614) | p-value | PTB (N = 157) | Control (N = 273) | p-value | |
Age | ||||||
Median (min.–max.) | 36 (18–70) | 28 (18–69) | 32 (18–70) | 28 (18–70) | ||
< 30 (%) | 115 (31.9) | 345 (56.2) | 64 (40.8) | 169 (61.9) | 0.258 | |
≥ 30 (%) | 246 (68.1) | 269 (43.8) | 93 (59.2) | 104 (38.1) | ||
Sex | ||||||
Male (%) | 223 (61.8) | 325 (52.9) | 101 (64.3) | 142 (52.0) | ||
Female (%) | 138 (38.2) | 289 (47.1) | – | 56 (35.7) | 131 (48.0) | – |
Bold p-value shows that there are significant differences between PTB and controls