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Pyroglyphidae

Pyroglyphidae is a family of dust mites that are common household pests and a major source of allergens.
These microscopic mites thrive in warm, humid environments and feed on human skin flakes and other organic matter.
Pyroglyphidae mites are a significant trigger for asthma and other respiratory issues, as well their droppings and body fragments can cause allergic reactions.
Identifying and understanding Pyroglyphidae is crucial for effective dust mite control and management of related health conditions.
This MeSH term provides a concise overview of this important family of indoor allergens.

Most cited protocols related to «Pyroglyphidae»

1
Mapping T-Cell Epitopes from Allergens
Cited 11 times

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Publication 2015
Allergens Antigens Antigens, Bacterial Biological Assay Bordetella pertussis Cells Cockroaches Cytokine Donors Enzyme-Linked Immunospot Assay Fingers Immunogenicity, Vaccine Mycobacteroides immunogenum PBMC Peripheral Blood Mononuclear Cells Peptides Phleum Pyroglyphidae Tissue Donors
2
Lung Function and Asthma Severity in Puerto Ricans
Cited 10 times

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Publication 2012
Adrenal Cortex Hormones Adult African American Albuterol Allergens Asthma Bronchodilator Agents Child Cockroaches Dermatophagoides pteronyssinus antigen p 1 Environmental Exposure Ergocalciferol Health Insurance Hospitalization Households Hypersensitivity Index, Body Mass LAMP3 protein, human Negroid Races Nicotiana tabacum Parent Plasma Premature Birth Pyroglyphidae Respiratory Physiology Smoke Sperm Injections, Intracytoplasmic Uterus
3
Eosinophil Activation in Allergic Asthma
Cited 7 times
The study protocol was approved by the University of Wisconsin-Madison Health Sciences Institutional Review Board. Informed written consent was obtained from subjects prior to participation. For studies of in vitro eosinophil activation, peripheral blood eosinophils were obtained from allergic subjects with and without mild asthma. Subjects with prescriptions for low doses of inhaled corticosteroids did not use their corticosteroids the day of the blood draw. Eosinophils were purified by negative selection as previously described [20 (link)]. Briefly, heparinized blood was diluted 1:1 in HBSS and was overlaid above Percoll (1.090 g/ml). After centrifugation at 700 × g for 20 min at room temperature, the mononuclear cells were removed from the plasma/percol interface and erythrocytes were eliminated from the cell pellet by hypotonic lysis. The remaining pellet was resuspended in 2% NCS in HBSS. Cells were then incubated with anti-CD16, anti-CD3, anti-CD14 and anti-Glycophorin-A beads from Miltenyi (San Diego, CA), and run through an AutoMACS (Miltenyi). Eosinophil preparations with purity > 99% and viability ∼98% were used the same day, ∼5 h after the blood draw.
For studies of in vivo eosinophil activation, bronchoscopy and bronchoalveolar lavage (BAL) were performed 48 h after segmental bronchoprovocation with an allergen (SBP-Ag) in subjects with mild asthma who were allergic to ragweed, dust mite, or cat dander allergens [20 (link)]. Eosinophils were purified, as previously described [12 (link)], from the BAL cell preparation (BAL EOS) and from peripheral blood (BBL EOS) of the same allergen-challenged subject. On the same day, eosinophils were also purified from peripheral blood of a control unchallenged subject (control EOS (Ctrl)).
Esnault S., Johansson M.W., Kelly E.A., Koenderman L., Mosher D.F, & Jarjour N.N. (2017). IL-3 Up-regulates and Activates Human Eosinophil CD32 and αMß2 Integrin Causing Degranulation. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 47(4), 488-498.
Publication 2016
Adrenal Cortex Hormones Allergens Asthma BLOOD Bronchoscopy Cells Centrifugation Dander Dimercaprol Eosinophil Erythrocytes Ethics Committees, Research Glycophorin A Hemoglobin, Sickle Muromonab-CD3 Percoll Plasma Prescriptions Pyroglyphidae
4
Asthma and Allergy Assessments in Peru
Cited 7 times
We carried out home visits to enrol participants, administer the survey and perform physical testing. During the first visit, we asked about asthma and allergy symptoms using a validated questionnaire,17 asthma medications use, biomass fuel exposures and sociodemographics.
We conducted physical testing during a second visit. After measuring height and weight, we conducted spirometry presalbutamol and postsalbutamol according to standard guidelines.18 (link) We measured exhaled nitric oxide (eNO) levels in parts per billion (ppb) and applied allergy skin tests for cockroach, dust mite mix, cat hair, dog epithelium, mouse epithelium and mixed moulds. We measured approximate PM2.5 concentrations (μg/m3) for 48 h using a portable nephelometer in a random subset of 100 households in Lima and 70 in Tumbes. We obtained outdoor PM data in Lima from DIGESA (http://www.digesa.sld.pe).
This study was approved by the Institutional Review Boards of the Johns Hopkins Bloomberg School of Public Health in Baltimore, USA, and AB PRISMA in Lima, Peru.
Robinson C.L., Baumann L.M., Romero K., Combe J.M., Gomez A., Gilman R.H., Cabrera L., Gonzalvez G., Hansel N.N., Wise R.A., Barnes K.C., Breysse P.N, & Checkley W. (2011). Effect of urbanisation on asthma, allergy and airways inflammation in a developing country setting. Thorax, 66(12), 1051-1057.
Publication 2011
Asthma Cockroaches Epithelium Ethics Committees, Research Fungus, Filamentous Hair Households Hypersensitivity Mice, House Oxide, Nitric Pharmaceutical Preparations Physical Examination prisma Pyroglyphidae Spirometry Test, Skin Visit, Home
5
Childhood Allergic Sensitization Profiles
Cited 6 times

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Publication 2008
Allergens anti-IgE Cockroaches Diagnosis Immunoradiometric Assays Mus Pyroglyphidae Serum Umbilical Cord Blood

Most recents protocols related to «Pyroglyphidae»

1
Seasonal and Perennial Allergic Conjunctivitis Study
Included patients were aged ≥18 years with a documented history of AC, a documented positive skin prick test and/or positive validated IgE test to perennial allergen (eg cat dander, dog dander, dust mites and/or cockroach) or to seasonal allergen (eg grass, ragweed, and/ or tree pollen) within 6 months before the study, or a positive skin prick test at Visit 1a and showing signs and symptoms of AC, ie tearing, itching and redness, that were likely to continue for the next weeks. The patients had to have a minimum score of 4 on a 0–10 numeric rating scale (0, no symptom; 10, very severe symptom) in at least one of three categories (ocular itching, ocular redness, and ocular tearing). The main exclusion criteria were a history of known contraindications or sensitivities to the use of the drug or any of its components; intraocular surgery or planned surgery during study participation and within 2 weeks after follow-up; ocular trauma in the 6 months before the study; clinical evidence of ocular herpes simplex or ocular herpes zoster infectious disease; or any clinically significant (CS) external ocular disease within 30 days before study start.
Kuna P., Jutel M., Pulka G., Tokarski S., Arranz P., Hernández G, & Fernández Hernando N. (2023). Safety and Tolerability of Bilastine 0.6% Ophthalmic Solution: An 8-Weeks Phase III Study. Clinical Ophthalmology (Auckland, N.Z.), 17, 735-746.
Publication 2023
Allergens Cockroaches Communicable Diseases Dander Erythema Eye Eye Injuries Herpes Zoster Ophthalmicus Hypersensitivity Keratitis, Herpetic Operative Surgical Procedures Patients Pharmaceutical Preparations Poaceae Pollen Pyroglyphidae Test, Skin Trees
2
Diagnosing Pediatric Allergic Rhinitis Criteria
The diagnostic criteria applied in this study are based on the Guidelines for the Diagnosis and Treatment of Allergic Rhinitis in Children (2022, revised edition) (4 (link)), which include the following typical symptoms of AR: watery nose, itching, stuffy nose, sneezing (note: two or more items needed to be met, and had to last or accumulate for more than 1 hour every day). At the same time, the following were considered typical signs of AR: pale and edema of the nasal mucosa and watery secretion of the nasal cavity. Allergen detection was determined as follows: dust mite serum-specific immunoglobulin E (IgE) was positive.
Li L., Cui X., Zhang X., Zheng L., Sun X., Yang C., Shu J, & Liu G. (2023). Serum vitamin D3 deficiency can affect the efficacy of sublingual immunotherapy in children with allergic rhinitis: a retrospective cohort study. Journal of Thoracic Disease, 15(2), 649-657.
Publication 2023
Allergens Child Diagnosis Edema Immunoglobulin E Nasal Cavity Nasal Mucosa Nose Pyroglyphidae Rhinitis, Allergic Secretions, Bodily Serum
3
Efficacy of SLIT in Pediatric Dust Mite Allergic Rhinitis
In this study, 153 patients with AR who received SLIT with Dermatophagoides farinae (D. farinae) drops in the Otorhinolaryngology Department of Tianjin Children’s Hospital from January 2020 to October 2021 were selected as the study objects. The patient’s sex, age, serum vitamin D3 levels, family history of allergic disease, food allergies, their caregiver’s education level, asthma status, whether they had used acarid products, etc. were collected retrospectively. All patients included in this study recorded their visual simulation scores, symptom scores, medication scores, and quality of life scores to evaluate the efficacy of SLIT. The primary endpoint of this study was the efficacy of patients treated with SLIT, and the independent influencing factors affecting the efficacy of SLIT were analyzed.
The enrolled patients were required to fully meet the following conditions: (I) diagnosed with AR, with or without other allergic diseases; (II) 3–14 years old, male or female; (III) allergen detection results: dust mites were positive, closely related to clinical symptoms and were the main allergen; (IV) allergens could be avoided as much as possible during treatment; (V) willing to receive SLIT and able to comply with the program and receive follow-up. The exclusion criteria were as follows: (I) patients with infectious rhinitis; (II) patients who could not understand the purpose of this study and refused to cooperate with follow-up; (III) those with incomplete data. The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013). This study was approved by the Ethics Committee of Tianjin Children’s Hospital (No. KY2020-47) and informed consent was taken from all the patients’ guardians.
Li L., Cui X., Zhang X., Zheng L., Sun X., Yang C., Shu J, & Liu G. (2023). Serum vitamin D3 deficiency can affect the efficacy of sublingual immunotherapy in children with allergic rhinitis: a retrospective cohort study. Journal of Thoracic Disease, 15(2), 649-657.
Publication 2023
Allergens Asthma Child Cholecalciferol Common Cold Dermatophagoides farinae Ethics Committees, Clinical Food Allergy Hypersensitivity Legal Guardians Males Patients Pharmaceutical Preparations Pyroglyphidae Serum Woman
4
Quantitative Allergen Detection in Serum
We collected 3 mL of venous blood to separate the serum for use and used the Fubok allergen detector and its allergen diagnostic reagent produced by Jiangsu Haooubo Biological Medicine Co., Ltd. (Suzhou, Jiangsu Province, China) to determine the specific IgE of the corresponding allergen in the serum. The system adopts the enzyme-linked immunostaining method to detect the serum-specific IgE content, which is a quantitative detection. Inhalation allergens include house dust mites, dust mites, mugwort, ragweed, cockroaches, cat epithelia, dog epithelia, house dust, Alternaria, and willow. Food allergens include peanut, egg, milk, cod, wheat flour, shrimp, soybean, crab, beef, and mutton.
Li L., Cui X., Zhang X., Zheng L., Sun X., Yang C., Shu J, & Liu G. (2023). Serum vitamin D3 deficiency can affect the efficacy of sublingual immunotherapy in children with allergic rhinitis: a retrospective cohort study. Journal of Thoracic Disease, 15(2), 649-657.
Publication 2023
Allergens Alternaria Arachis hypogaea Artemisia vulgaris Beef Biopharmaceuticals Brachyura Cockroaches Diagnosis Enzymes Epithelium Food House Dust Inhalation Milk, Cow's Pyroglyphidae Serum Soybeans Veins Wheat Flour Willow
5
Retrospective Analysis of Pediatric SLIT for Dust Mite-Induced Allergic Rhinitis
This study retrospectively analyzed the clinical data of 153 AR patients who received SLIT in the Department of Otolaryngology, Tianjin Children’s Hospital from January 2020 to October 2021. The patients’ demographic, follow-up methods, complications efficacy, compliance data, etc. were collected. The enrolled patients were required to fully meet the following conditions: (I) patients diagnosed with AR, with or without other allergic diseases; (II) 3–14 years old, male or female; (III) allergen detection results: dust mites were positive, closely related to clinical symptoms, and were the main allergen; (IV) allergens could be avoided as much as possible during treatment; (V) patients were willing to receive sublingual immunotherapy, and were able to comply with the program and receive follow-up. The exclusion criteria were as follows: patients with infectious rhinitis; patients who could not understand the purpose of this study and refused to cooperate with follow-up; and patients with incomplete data. A total of 136 patients were included in the final statistical analysis and 17 patients were excluded. The flow chart of this study is shown in Figure 1. The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013). This study was approved by the Ethics Committee of Tianjin Children’s Hospital (No. KY2020-47) and individual consent for this retrospective analysis was waived.
Li L., Cao B., Sun X., Yang C, & Liu G. (2023). Internet follow-up can improve the compliance of sublingual immunotherapy in children with allergic rhinitis: a retrospective cohort study. Translational Pediatrics, 12(2), 185-193.
Publication 2023
Allergens Child Common Cold Ethics Committees, Clinical Hypersensitivity Males Patients Pyroglyphidae Sublingual Immunotherapy Woman

Top products related to «Pyroglyphidae»

1
Immunocap by Thermo Fisher Scientific
Sourced in Sweden, United States, Germany, Denmark, France
The ImmunoCAP is a laboratory instrument used for in vitro allergen-specific IgE testing. It provides quantitative measurement of IgE antibodies to a wide range of allergens. The ImmunoCAP system utilizes fluorescent enzyme immunoassay technology to detect and measure IgE levels in patient samples.
2
Immunocap system by Thermo Fisher Scientific
Sourced in Sweden, United States, Germany, Denmark, United Kingdom
The ImmunoCAP system is a fully automated immunoassay analyzer used for the quantitative measurement of specific IgE antibodies in human serum or plasma. It provides accurate and reliable results for the in vitro diagnosis of allergic diseases.
3
Dexamethasone (dex) by Merck Group
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Dexamethasone is a synthetic glucocorticoid medication used in a variety of medical applications. It is primarily used as an anti-inflammatory and immunosuppressant agent.
4
Alkaline phosphatase conjugated monoclonal anti human ige antibodies by BD
Sourced in United States
Alkaline phosphatase-conjugated monoclonal anti-human IgE antibodies are a laboratory reagent used in immunoassays to detect and measure the presence of IgE antibodies in biological samples. They are produced by fusing myeloma cells with antibody-producing B cells to create a stable hybridoma cell line that secretes the desired monoclonal antibody. The antibodies are then conjugated with the enzyme alkaline phosphatase, which can be used to generate a measurable signal upon interaction with a suitable substrate.
5
Dermatophagoides pteronyssinus by Stallergenes Greer
Sourced in United States
Dermatophagoides pteronyssinus is a species of dust mite. It is a small arthropod that commonly lives in household dust. The core function of this product is to serve as a laboratory reference material for research and testing purposes.
6
Hdm extract by Stallergenes Greer
Sourced in United States
HDM extract is a laboratory product used for the extraction and purification of house dust mite allergens. It serves as a source material for various research and diagnostic applications related to house dust mite allergy.
7
Ovalbumin (ova) by Merck Group
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The OVA is a laboratory equipment product designed for the detection and analysis of eggs or ova. It provides a reliable and standardized method for sample preparation and observation. The core function of the OVA is to facilitate the identification and quantification of eggs or ova in various samples.
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Immunocap 250 by Thermo Fisher Scientific
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The ImmunoCAP 250 is a fully automated lab equipment for the detection and quantification of specific IgE antibodies in patient samples. It utilizes fluorescence-enzyme immunoassay technology to provide reliable and standardized results for the diagnosis of allergies and related conditions.
9
Phadia 250 by Thermo Fisher Scientific
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The Phadia 250 is an automated immunoassay analyzer designed for in-vitro diagnostic testing. It is capable of processing a range of immunoassay tests, including those for allergy, autoimmunity, and infectious disease. The Phadia 250 provides reliable and efficient sample processing and analysis to support clinical decision-making.
10
Phadia 1000 by Thermo Fisher Scientific
Sourced in Sweden, United States
The Phadia 1000 is an automated clinical diagnostic instrument designed for in-vitro allergy testing. It utilizes fluorescence enzyme immunoassay (FEIA) technology to measure specific IgE antibodies in patient samples. The Phadia 1000 is capable of processing multiple samples simultaneously and provides quantitative results for a range of allergens.

More about "Pyroglyphidae"

Pyroglyphidae, a family of dust mites, are common household pests and a major source of allergens.
These microscopic acarids thrive in warm, humid environments and feed on human skin flakes and other organic matter.
Also known as house dust mites, Pyroglyphidae mites are a significant trigger for asthma, rhinitis, and other respiratory issues, as their droppings and body fragments can cause allergic reactions.
Identifying and understanding Pyroglyphidae is crucial for effective dust mite control and management of related health conditions.
The ImmunoCAP system, which includes the ImmunoCAP 250 and Phadia 250/1000 instruments, is a widely used diagnostic tool for detecting IgE antibodies to Pyroglyphidae and other indoor allergens like Dermatophagoides pteronyssinus (house dust mite).
Dexamethasone, a synthetic glucocorticoid, and alkaline phosphatase-conjugated monoclonal anti-human IgE antibodies are sometimes utilized in research and clinical settings to study the immune response to Pyroglyphidae allergens.
Animal models, such as the ovalbumin (OVA) challenge, can also provide insights into the mechanisms underlying Pyroglyphidae-induced allergic reactions.
Effective management of Pyroglyphidae-related health issues often involves a combination of environmental control measures, allergen immunotherapy, and pharmacological interventions.
By understanding the biology and impact of this family of dust mites, researchers and clinicians can develop more effective strategies for improving the quality of life for individuals affected by Pyroglyphidae-related allergies and respiratory conditions.