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Glycyrrhiza glabra

Glycyrrhiza glabra, commonly known as licorice, is a perennial herb native to the Mediterranean region and parts of Asia.
This plant is valued for its roots, which contain a variety of bioactive compounds with potential therapeutic applications.
PubCompare.ai is an AI-driven platform that can enhance your Glycyrrhiza glabra research by helping you locate the most reliable protocols from literature, preprints, and patents, while providing detailed comparisons to identify the optimal procedures and products.
This tool can optimize your experiments and ensure reproducibility, making it the ultimate resource for Glycyrrhzia glabra research.

Most cited protocols related to «Glycyrrhiza glabra»

1
Olfactory Performance and Cognitive Abilities
Cited 4 times
Session 1 included a sociodemographic-based questionnaire and testing of cognitive ability using the verbal intelligence test (MWT-B) (Lehrl 1996 ), and the trail making test (TMT-A and -B) measuring executive functioning (Crowe 1998 (link)). Emotional states were tested using PANAS scales (Watson et al. 1988 (link)). As state of satiety is known to influence olfactory performance (Albrecht et al. 2009 (link)), subjects were also asked to rate their current state of hunger (1 = not hungry at all, 10 = very hungry), their desire for food (1 = very weak, 10 = very strong), and the fullness of their stomach (1 = not full at all, 10 = very full) on a visual analog scale.
The standard odors of the Sniffin’ Sticks test battery (Burghart Instruments) were used to test olfactory performance, hedonic, and intensity ratings. The original Sniffin’ Sticks test includes 3 subtests measuring nasal chemosensory function using pen-like devices for odor presentation: odor threshold, odor discrimination, and odor identification (Kobal et al. 1996 (link); Hummel et al. 1997 (link)). Detection thresholds of n-butanol were determined using a single-staircase, 3 alternative forced choice (3-AFC) procedure, that is, subjects were presented with 3 sticks and had to decide which one contained n-butanol. Odor discrimination was tested using 16 triplets of odorants, again presented as a 3-AFC procedure, that is, subjects again were confronted with 3 sticks and had to indicate which one smelled different. The odor identification test consisted of 16 commonly known every day odorants (orange, shoe leather, cinnamon, peppermint, banana, lemon, liquorice, turpentine, garlic, coffee, apple, clove, pineapple, rose, anise, and fish) using a multiple-choice answering format with 4 odors each. The standard testing procedure was extended by the assessment of odor intensity and hedonics for n-butanol in the highest concentration.
All 4 olfactory tests were carried out birhinally. The results of the 3 Sniffin’ Sticks subtests were summed up to the so-called “TDI score”, which characterizes the individual olfactory performance as the sum of odor threshold, discrimination, and identification ability (Kobal et al. 1996 (link); Hummel et al. 1997 (link)). Directly after the olfactory tests, emotional states using PANAS scales were assessed again.
Derntl B., Schöpf V., Kollndorfer K, & Lanzenberger R. (2012). Menstrual Cycle Phase and Duration of Oral Contraception Intake Affect Olfactory Perception. Chemical Senses, 38(1), 67-75.
Publication 2012
Anise Banana Butyl Alcohol Cinnamomum verum Citrus limon Coffee Debility Discrimination, Psychology Emotions Fishes Garlic Glycyrrhiza glabra Hunger Intelligence Tests Medical Devices Mentha piperita Nose Odorants Odors Pineapple Satiation Sense of Smell Stomach Syzygium aromaticum Triplets Turpentine Visual Analog Pain Scale
2
Assessing Olfactory Identification with Sniffin' Sticks
Cited 3 times

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Publication 2018
Banana caryophylli flos Cinnamomum verum Citrus limon Coffee Feelings Fishes Glycyrrhiza glabra Mentha piperita Odorants Pineapple Sense of Smell
3
Comprehensive Licorice Sample Analysis
Cited 3 times
A total of 51 licorice samples sold as bulk root powders, sticks, or capsules were either purchased online and from Chicago metropolitan area stores or acquired through our collaborative network. Sampling of BDS capsules was restricted to dried preparations (powdered plant tissue in gelatin capsules). To protect the manufacturer’s identity, the samples were reported with internal Botanical Center codes (Tables 1–4). Samples BC629, BC693–694, BC711, BC746–747, BC749, BC751–755, BC772, BC774, and BC778 were botanically/macroscopically verified prior to inclusion.
Simmler C., Anderson J.R., Gauthier L., Lankin D.C., McAlpine J.B., Chen S.N, & Pauli G.F. (2015). Metabolite Profiling and Classification of DNA-Authenticated Licorice Botanicals. Journal of natural products, 78(8), 2007-2022.
Publication 2015
Capsule Dietary Fiber Gelatins Glycyrrhiza glabra Plant Capsule Plant Roots SELL protein, human Tissues
4
Standardized Herbal Extract Production Protocol
Cited 2 times
The formula to produce 5 g of dried extract of KKT comprised the following 14 components: Astragali Radix (3 g, root of Astragalus propinquus Schischkin or Astragalus mongholicus Bunge), Bupleuri Radix (3 g, root of Bupleurum falcatum L.), Ziziphi Semen (3 g, seed of Ziziphus jujuba var. spinosa [Bunge] Hu ex H.F.Chow), Atractylodis Lanceae Rhizoma (3 g, rhizome of Atractylodes lancea [Thunb.] DC. or Atractylodes chinensis [Bunge] Koidz.), Ginseng Radix (3 g, root of Panax ginseng C.A.Mey.), Poria (3 g, sclerotium of Wolfiporia cocos Ryvarden et Gilbertson), Longan Arillus (3 g, arillus of Dimocarpus longan Lour.), Polygalae Radix (2 g, root of Polygala tenuifolia Willd.), Gardeniae Fructus (2 g, fruit of Gardenia jasminoides J.Ellis), Ziziphi Fructus (2 g, fruit of Ziziphus jujuba var. inermis [Bunge] Rehder), Angelicae Radix (2 g, root of Angelica acutiloba [Siebold & Zucc.] Kitag. or Angelica acutiloba var. sugiyamae Hikino), Glycyrrhizae Radix (1 g, root of Glycyrrhiza uralensis Fisch. ex DC. or Glycyrrhiza glabra L.), Zingiberis Rhizoma (1 g, rhizome of Zingiber officinale Roscoe), and Saussureae Radix (1 g, root of Aucklandia costus Falc.). All raw materials were supplied by Tsumura & Co. (Tokyo, Japan). The dry-powdered extract of KKT (lot number: 351152900 and 361095300) was produced by Tsumura & Co. Briefly, the mixture of the 14 raw materials was extracted in boiling water for 1 h, and the extract was then separated from insoluble waste. The separated extract was concentrated under reduced pressure and then spray-dried to produce the extract powder of KKT (hereafter termed “KKT”). The quality of KKT was confirmed to meet the Japanese Pharmacopoeia and our company’s standards; specifically, the following ingredients were included (with their corresponding ranges): saikosaponin b2 (0.8–3.2 mg); geniposide (27–81 mg); glycyrrhizinic acid (6–18 mg), in 5 g of KKT. All voucher specimens of the raw materials used for each lot of KKT were deposited in the herbarium of Tsumura & Co., with batch numbers (Table S1). For use in the elevated plus maze (EPM) test, KKT was suspended in 10 mL of distilled water immediately prior to use and was orally administered. To administer KKT without manually handling the mice in the IntelliCage experiment, KKT was suspended in tap water in the water bottles at a concentration of 1% (w/v) and placed in the cage. The bottles of KKT suspension were refreshed every 2 to 3 days.
Oizumi H., Miyazaki S., Tabuchi M., Endo T., Omiya Y, & Mizoguchi K. (2020). Kamikihito Enhances Cognitive Functions and Reward-Related Behaviors of Aged C57BL/6J Mice in an Automated Behavioral Assay System. Frontiers in Pharmacology, 11, 1037.
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Publication 2020
Angelica Astragalus mongholicus Astragalus Plant Atractylodes Atractylodes lancea Bupleurum root Dimocarpus longan Elevated Plus Maze Test Fruit Gardenia geniposide ginger root Glycyrrhiza glabra Glycyrrhiza uralensis root extract Glycyrrhizic Acid Huang Qi Japanese Mice, House Panax ginseng Panax ginseng root Plant Roots Polygala tenuifolia Poria Powder Pressure Rhizome saikosaponin B2 Saussurea costus Wolfiporia Wolfiporia extensa Zingiber officinale Ziziphus
5
Comprehensive CYP72A Protein Sequence Analysis
Cited 2 times
A total of 209 CYP72A protein sequences were acquired via five methods: the cytochrome P450 homepage BLAST server [33 (link)], The Arabidopsis Information Resource page (TAIR; https://www.arabidopsis.org/), MaizeGDB BLAST server (http://www.maizegdb.org/), Dr. David Nelson, and through BLAST searching sequence databases (NCBI Genbank). An incomplete protein complement of CYP72A sequences had been previously identified in sacred lotus and papaya [33 (link),34 ] and rice [13 (link)]. These sequences were obtained from the Cytochrome P450 Homepage. A. thaliana and S. lycopersicum sequences were used in extensive BLAST searches in Genbank to identify additional CYP72A sequences. Z. mays sequences were utilized in BLAST searches in MaizeGDB to identify the full set of CYP72A in the maize B73 genome. The CYP names used in the analysis were assigned by Dr. David Nelson; otherwise, unnamed sequences were assigned sequence tags containing the corresponding species and accession number (e.g. Tc_EOX99507). The following plant species are represented: Zea mays (maize), Oryza sativa (rice), Sorghum bicolor (sorghum), Lolium rigidium (rye grass), Brachypodium distachyon (purple false brome), Triticum aestivum (common wheat), Hordeum vulgare (barley), Echinochloa phyllopogon (late watergrass), Coptis japonica (gold thread), Nelumbo nucifera (sacred lotus), Vitis vinifera (grape), Jatropha curcas (barbados nut), Ricinus communis (castor bean), Populus richocarpa (black cottonwood), Glycyrrhiza uralensis (Chinese licorice), Glycine max (soy bean), Medicago truncatula (barrel clover), Glycyrrhiza echinata (licorice), Cicer arietinum (chick pea), Lotus japonicas (lotus), Fragaria vesca (strawberry), Prunus persica (peach), Theobroma cacao (cocoa tree), Arabidopsis thaliana, Capsella rubella (red shepherd’s purse), Brassica rapa (oil Seed), Carica papaya (papaya), Catharanthus roseus (Madagascar periwinkle), Nicotiana tabacum (tobacco), Nicotiana plumbaginifolia (tex mex tobacco), Solanum lycopersicum (tomato), Solanum tuberosum (potato), and Panax ginseng (ginseng) (Table 1). To be included in the set, sequences had to be >55% identical and appear to be entire. Sequences with large gaps (particularly in important structural motifs) or insertions relative to the entire set were excluded. In order to root the CYP72A phylogenetic tree, A. thaliana sequence CYP734A1 was chosen as an outlier based on previous phylogenies [12 ].
Prall W., Hendy O, & Thornton L.E. (2016). Utility of a Phylogenetic Perspective in Structural Analysis of CYP72A Enzymes from Flowering Plants. PLoS ONE, 11(9), e0163024.
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Publication 2016
Amino Acid Sequence Arabidopsis Arabidopsis thalianas Brachypodium distachyon Brassica rapa Cacao Capsella Capsella bursa pastoris Carica papaya Castor Beans Catharanthus roseus Chickpea Cicer arietinum Clover Coptis japonica Echinochloa Fragaria vesca Genome Glycyrrhiza glabra Glycyrrhiza glabra extract Glycyrrhiza uralensis Gold Grapes Hordeum Hordeum vulgare Insertion Mutation Jatropha curcas Lolium Lotus Lycopersicon esculentum Medicago truncatula Nelumbo nucifera Nicotiana Nicotiana tabacum Oryza sativa Panax ginseng Plant Roots Plants Populus Populus fremontii Prunus persica Rice Ricinus communis Rubella Solanum tuberosum Sorghum Sorghum bicolor Soybeans Strawberries Trees Triticum aestivum Vitis Zea mays

Most recents protocols related to «Glycyrrhiza glabra»

1
Nicotine Replacement Therapy Comparison
Two NRT products were tested, Nicorette Peppermint 2 mg lozenge, and Nicotinell Licorice 2 mg gum. The products weigh 0.6 g and 1.2 g per unit of use, respectively. The lozenge contains nicotine in the form of resinate, fillers (mannitol, xanthan gum, gum arabic, magnesium stearate, hypromellose, titanium dioxide, microcrystalline cellulose, potassium silicate, polysorbate 80), pH adjuster (sodium carbonate), sweetener (sucralose, acesulfame K) and flavorings. The gum contains nicotine polacrilex, chewing gum base, sweetener (acesulfame K, saccharin, sodium saccharin, sorbitol, xylitol, mannitol), pH adjusters (calcium carbonate, sodium carbonate, sodium bicarbonate), flavoring, glycerol, gelatine, titanium dioxide, canauba wax and talcum powder.
Back S., Masser A.E., Rutqvist L.E, & Lindholm J. (2023). Harmful and potentially harmful constituents (HPHCs) in two novel nicotine pouch products in comparison with regular smokeless tobacco products and pharmaceutical nicotine replacement therapy products (NRTs). BMC Chemistry, 17(1), 9.
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Publication 2023
acesulfame potassium Bicarbonate, Sodium Carbonate, Calcium Gelatins Glycerin Glycyrrhiza glabra Gum Arabic Gums, Chewing Hypromellose magnesium stearate Mannitol Mentha piperita microcrystalline cellulose Nicorette Nicotine Nicotine Polacrilex Polysorbate 80 Potassium Saccharin Saccharin Sodium Silicates sodium carbonate Sorbitol sucralose Sweetening Agents Talcum Powder titanium dioxide xanthan gum Xylitol
2
COVID-19 Cough Treatment Protocol
Patients over 18 years of age with cough and positive reverse transcriptase polymerase chain reaction (RT-PCR) test for COVID-19 with the onset time of less than 5 days were included in the study.
Exclusion criteria were as follows: pregnancy or breastfeeding, history of allergy to noscapine, licorice, diphenhydramine, morphine or other excipients of the study medications, history of seizure, diarrhea or diabetes, consumption of warfarin, benzodiazepines, opioid agonists, and other antitussive medications.
Barati S., Feizabadi F., Khalaj H., Sheikhzadeh H., Jamaati H.R., Farajidavar H, & Dastan F. (2023). Evaluation of noscapine-licorice combination effects on cough relieving in COVID-19 outpatients: A randomized controlled trial. Frontiers in Pharmacology, 14, 1102940.
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Publication 2023
agonists Allergic Reaction Antitussive Agents Benzodiazepines Cough COVID 19 Diabetes Mellitus Diarrhea Diphenhydramine Excipients Glycyrrhiza glabra Morphine Noscapine Opioids Patients Pregnancy Reverse Transcriptase Polymerase Chain Reaction Seizures Warfarin
3
Sensory Test and Food Preference
After an overnight fast and the sensory test, each participant was given 20 minutes to eat from a buffet with different foods to assess preferences for sweet-taste and content of sucrose and fat. Foods in the test meal included: digestive biscuits, maria biscuit, crispbread, salty cracker, hardtack, strawberry jam, sweet hazelnut cocoa spread, butter, raisins, dried apricots, small cinnamon rolls, ham, salami, dried whale meat, chocolate, mixed gummies and liquorice, milk, bread rolls, pears, oranges, sugar, honey, orange juice, coffee, tea. See Supplemental Table S1 for a brand-specific list. Each plate from the buffet was weighed before and after the 20 minutes to estimate the intake of each food for the participant. In case the participant did not finish eating and/or drinking before the 20 minutes, we weighed the leftover food and/or drinks and subtracted the amount from the amount taken from the buffet.
Senftleber N.K., Skøtt Pedersen K., Schnoor Jørgensen C., Pedersen H., Bjerg Christensen M.M., Kabel Madsen E., Andersen K., Jørsboe E., Gillum M.P., Frøst M.B., Hansen T, & Jørgensen M.E. (2023). The effect of sucrase-isomaltase deficiency on metabolism, food intake and preferences: protocol for a dietary intervention study. International Journal of Circumpolar Health, 82(1), 2178067.
Publication 2023
Apricot Bread Butter Carbohydrates Chocolate Cinnamon Cocoa Powder Coffee Digestive System Food Glycyrrhiza glabra Hazelnuts Honey Meat Milk, Cow's Pears Raisins Sodium Chloride, Dietary Strawberries Sucrose Taste Whales
4
Medicinal Plant Extraction and Characterization
Trifolium pratense L. samples were collected in Trifolium pratense L. fields in Laičiai, Kupiškis district, Lithuania (latitude 55°53024.2″ N; longitude 25°19036.0″ E). The collections of Trifolium pratense L. flower buds were made on the 31 July 2021. Glycyrrhiza glabra L. roots (the country of origin is China) were bought from LSMU pharmacy (Kaunas, Lithuania). Myristica fragrans seeds’ country of origin was Grenada (supplier Spaisvilė, Pašaltuonys, Lithuania). Voucher specimens (Trifolium pratense L.—J21731; Myristica fragrans Houtt.—I18922; and Glycyrrhiza glabra L.—K20911) were placed for storage at the Herbarium of the Department of Drug Technology and Social Pharmacy, Lithuanian University of Health Sciences, Lithuania.
In this experiment, purified water was prepared with GFL2004 (GFL, Burgwedelis, Germany). Deionised water was prepared with Millipore, SimPak 1 (Merck, Darmstadt, Germany). The following reagents were used: standards genistein, daidzein, and glycyrrhizin acid (Sigma Aldrich, Steinheim, Germany). 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl radical (DPPH), and β-CDs purchased from Sigma Aldrich (Hamburg, Germany); aluminium chloride, hexaethylenetetraamine, dimethyl sulfoxide (DMSO), acetic acid, and Sabouraud dextrose agar (dehydrated) obtained from Sigma-Aldrich (Buchs, Switzerland); potassium persulfate obtained from Alfa Aesar (Karlsruhe, Germany); ethanol (96%) obtained from Vilniaus Degtinė (Vilniaus, Lithuania); Folin–Ciocalteu’s phenol reagent (Merck, Darmstadt, Germany); monosodium phosphate, ferrous sulfate heptahydrate, saline phosphate buffer, and hydrogen peroxide obtained from Sigma Aldrich (Schnelldorf, Germany); disodium hydrogen phosphate obtained from Merck (Darmstadt, Germany); Mueller–Hinton Agar obtained from BBL (Baltimore, MD, USA); foetal bovine serum obtained from FBS (Gibco, TX, USA); and as the shell material, alginic acid sodium salt from brown algae obtained from Sigma-Aldrich (Shanghai, China) was used. Calcium chloride (Farmalabor, Pozzillo, Italy) salt was used to formulate microcapsules as a crosslinker, which linked sodium alginate chains and formed a solid gel.
Kazlauskaite J.A., Matulyte I., Marksa M., Lelesius R., Pavilonis A, & Bernatoniene J. (2023). Application of Antiviral, Antioxidant and Antibacterial Glycyrrhiza glabra L., Trifolium pratense L. Extracts and Myristica fragrans Houtt. Essential Oil in Microcapsules. Pharmaceutics, 15(2), 464.
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Publication 2023
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid Acetic Acid Agar Aluminum Chloride Brown Algae Buffers Calcium chloride daidzein diphenyl Ethanol ferrous sulfate folin Genistein Glucose Glycyrrhiza glabra Glycyrrhiza glabra extract Glycyrrhizic Acid Microcapsules Myristica fragrans Peroxide, Hydrogen Phenol Phosphates Plant Embryos potassium persulfate Saline Solution Sodium Alginate Sodium Chloride sodium phosphate, dibasic Sulfonic Acids Sulfoxide, Dimethyl Trifolium pratense
5
Bioplastic Fabrication from Agricultural Waste
Tamarind seeds, berry seeds, licorice root, distilled water, glycerol, and white vinegar were used to fabricate the bioplastic samples. The agricultural lab of the Department of Agriculture of IUBAT provided the necessary seeds of berry and tamarind with licorice. Distilled water was collected from the environment lab of the Civil Engineering Department of IUBAT as well. We collected glycerol and white vinegar from a nearby shop.
Chowdhury M.A., Nayem H.o.s.s.a.i.n., Badrudduza M.D, & Rana M.M. (2023). Development and characterization of natural sourced bioplastic for food packaging applications. Heliyon, 9(2), e13538.
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Publication 2023
Berries Biopolymers Glycerin Glycyrrhiza glabra Glycyrrhiza glabra extract Plant Embryos Tamarindus indica Vinegar

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1
Recombinant human hmgb1 by R&D Systems
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Recombinant human HMGB1 is a cytokine-like protein that is involved in the regulation of various cellular processes, including gene transcription, DNA repair, and inflammation. It is produced using recombinant DNA technology.
2
Ampicillin by Merck Group
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Ampicillin is a broad-spectrum antibiotic used in laboratory settings. It is a penicillin-based compound effective against a variety of gram-positive and gram-negative bacteria. Ampicillin functions by inhibiting cell wall synthesis, leading to bacterial cell lysis and death.
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Pdms sylgard 184 silicone elastomer by Dow
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PDMS (Sylgard 184 Silicone Elastomer) is a two-component silicone-based polymer system used for creating flexible, transparent, and durable elastomeric materials. It consists of a base component and a curing agent that, when mixed and cured, form a cross-linked silicone polymer. PDMS has a wide range of physical and chemical properties that make it suitable for various laboratory and industrial applications.
4
6 benzyladenine 6 ba by Merck Group
Sourced in United States
6-benzyladenine (6-BA) is a synthetic plant growth regulator. It is a cytokinin, a class of plant hormones that promote cell division and differentiation. 6-BA is commonly used in plant tissue culture and propagation applications.
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Naphthaleneacetic acid by Merck Group
Sourced in Germany, United States
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H2o2 solution by Merck Group
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Wright s stain by Solarbio
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Wright's stain is a type of biological stain used for the differential staining of blood cells, particularly for the identification and morphological analysis of cells in blood smears. It is a combination of methylene blue and eosin, which stains the different components of blood cells in a distinct manner, allowing for their visualization and differentiation under a microscope.
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Erlotinib by Cayman Chemical
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Erlotinib is a tyrosine kinase inhibitor used as a laboratory research tool. It functions by inhibiting the epidermal growth factor receptor (EGFR) kinase activity.
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Dimethyl sulfoxide (dmso) by Merck Group
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More about "Glycyrrhiza glabra"

Glycyrrhiza glabra, also known as licorice, is a perennial herb native to the Mediterranean region and parts of Asia.
This versatile plant is prized for its roots, which contain a diverse array of bioactive compounds with potential therapeutic applications.
Licorice, scientifically classified as Glycyrrhiza glabra, belongs to the Fabaceae family and is closely related to other legumes like soybeans and peas.
Its roots have been used in traditional medicine for centuries, with a long history of use in various cultures.
The roots of Glycyrrhiza glabra are a rich source of phytochemicals, including glycyrrhizin, flavonoids, and saponins.
These bioactive compounds have been extensively studied for their anti-inflammatory, antioxidant, and potential anti-cancer properties.
Licorice root extracts have also shown promise in the management of conditions like liver disease, diabetes, and respiratory disorders.
To optimize your Glycyrrhiza glabra research, PubCompare.ai is an invaluable AI-driven platform that can help you locate the most reliable protocols from literature, preprints, and patents.
This tool provides detailed comparisons to identify the optimal procedures and products, ensuring the reproducibility and efficiency of your experiments.
In addition to Glycyrrhiza glabra, PubCompare.ai can also assist with research on related compounds and topics, such as Recombinant human HMGB1, Ampicillin, PDMS (Sylgard 184 Silicone Elastomer), 6-benzyladenine (6-BA), Naphthaleneacetic acid, H2O2 solution, Wright's stain, Erlotinib, DMSO, and Caco-2 cell lines.
By leveraging the power of AI, PubCompare.ai can help you streamline your research and make the most informed decisions, ultimately leading to more successful and impactful outcomes.