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Panax ginseng

Panax ginseng is a perennial plant native to Asia, known for its potentially beneficial effects on human health.
This adaptogenic herb has been used in traditional medicine for centuries, with research exploring its potential applications in areas such as cognitive function, immune system support, and stress management.
The PubCompare.ai platform can help optimize your Panax ginseg research by locating the best protocols from literature, preprints, and patents, while using intelligent comparisons to enhance reproducibility and accuracy.
Unlock the power of AI-driven insights to deepen your understanding of this fascinating botanical.

Most cited protocols related to «Panax ginseng»

1
Randomized Crossover Trial of Caffeinated Energy Drinks
Cited 6 times
The data that support the findings of this study are available from the corresponding author upon reasonable request.
This study was approved by the Institutional Review Board (IRB) at University of the Pacific (Stockton, CA). All participants were provided written informed consent consistent with university requirements for clinical studies involving human subjects. The clinical study was registered on ClinicalTrials.gov (NCT03196908).
This was a randomized, double‐masked (participants and care providers), placebo‐controlled, crossover clinical trial conducted at a university campus setting (July 2017 to December 2017). Healthy volunteers between the ages of 18 and 40 years who were willing to avoid ingestion of caffeine and energy drinks for 48 hours before each study day were eligible for enrollment. Participants were excluded if they had any known medical condition (confirmed through participant interview), were pregnant or breastfeeding, were current smokers, had a baseline QTc >450 ms, or brachial blood pressure >140/90 mm Hg. Those who were taking any chronic prescription or over‐the‐counter medications were excluded except those who had been taking oral contraceptives for over 1 month. An overnight fast (with allowance for water only) was required preceding every study day, and no food was allowed during the study monitoring period. A commercially available non‐caffeinated granola bar (Nature Valley Crunchy Oats ‘N Honey, General Mills) was provided after the 180‐minute time point upon participant request.
Participants were randomized into 1 of 3 intervention phases using a computer‐generated code from http://www.randomization.com. Participants received two 16‐oz bottles of a commercially available caffeinated energy drink brand (drink A), another brand of a caffeinated energy drink (drink B), or a placebo‐drink (placebo) on 3 separate days with a minimum 6‐day washout period in‐between. The beverages were consumed within a 60‐minute period but no faster than 1 bottle in 30 minutes. Based on the package labeling, both drink A and drink B contained caffeine (304–320 mg/32‐fl oz), taurine, glucuronolactone, and vitamins along with other proprietary ingredients.24 Some differences between the 2 energy drink brands include the presence of carnitine, guarana, and panax ginseng. The placebo drink contained carbonated water, lime juice, and cherry flavoring. All drinks were packaged in identical, masked containers prepared within 24 hours of administration and stored in a refrigerator before administration.
Shah S.A., Szeto A.H., Farewell R., Shek A., Fan D., Quach K.N., Bhattacharyya M., Elmiari J., Chan W., O'Dell K., Nguyen N., McGaughey T.J., Nasir J.M, & Kaul S. (2019). Impact of High Volume Energy Drink Consumption on Electrocardiographic and Blood Pressure Parameters: A Randomized Trial. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 8(11), e011318.
Publication 2019
Arm, Upper Beverages Blood Pressure Caffeine calcium oxide Carbonated Water Contraceptives, Oral Drugs, Non-Prescription Energy Drinks Ethics Committees, Research Food glucuronolactone Guarana Healthy Volunteers Honey Levocarnitine Oats Panax ginseng Placebos Prunus cerasus Taurine Vitamins
2
Predictors of Amputees' Walking Ability
Cited 6 times
Manuscripts were selected or eliminated based on the following criteria:

Inclusion criteria:

Adult subjects with unilateral or bilateral lower
limb amputation

Published after August 1, 2007

Examined the relationship between predictive
variables recorded prior to amputee rehabilitation and
measures of walking ability following rehabilitation

Studies using health outcomes with a mobility
component, such as the Functional Independence
Measure

English language

Observational, retrospective studies if
predictor variables were available

Randomized clinical trials

Exclusion criteria:

Non-adult

Prosthetic device or rehabilitation
interventions studies

Animal studies

Case reports and series

Letters, editorials, conference proceedings

Manuscripts from developing nations

Two authors independently assessed selected papers for content, quality,
and critical appraisal. Similar to the original Sansam et al. SR, a standardized
checklist was used to extract each report’s methods, population, outcome
measures, and predictive factors (5 (link)).
Additionally, the UK National Service Framework for Long-term Conditions (3 ,9 )
was used to assess the quality of each study, as it allows assessment of quality
in non-randomized cohort studies. The reports and data extracted were verified
by at least two independent authors who agreed on final scoring and data
extraction. The International Classification of Functioning, Disability and
Health (4 ) was used to present the
predictive factors identified from these studies. Following study evaluation and
data extraction, factors predictive of walking ability following LEA were
aggregated and compared narratively with the findings of the original Sansam et
al. SR.
Kahle J.T., Highsmith M.J., Schaepper H., Johannesson A., Orendurff M.S, & Kaufman K. (2016). PREDICTING WALKING ABILITY FOLLOWING LOWER LIMB AMPUTATION: AN UPDATED SYSTEMATIC LITERATURE REVIEW. Technology and innovation, 18(2-3), 125-137.
Publication 2016
Adult Amputees Conferences Disabled Persons Medical Devices Panax ginseng Rehabilitation Training Programs
3
Panax Species Reference Genomes
Cited 5 times
Three de novo assembly strategies were employed to reconstruct the reference genomes of the four Panax species (Supplementary Note 1). Briefly, short insert libraries (350 bp) of P. stipuleanatus and P. japonicus were constructed by Illumina Novaseq (Tianjin, China) and sequenced using the Illumina Novaseq platform (Illumina, USA). Then, ~20 Kb SMRTbell libraries were generated for each of the two Panax species and sequenced on the PacBio RSII platform (PacBio, USA). In addition, DNA fragments longer than 50 kb were used to construct a 10× Gemcode library with a Chromium instrument (10× Genomics) and sequenced using the Illumina Novaseq platform (Illumina, USA). Finally, digested genomic DNA was used to construct Hi-C library for the two species and sequenced using the Illumina Novaseq platform (Illumina, USA). In contrast, two alternative strategies using the Nanopore platform (Nanopore, UK) was employed to assemble the reference genomes of P. ginseng and P. quinquefolius, respectively. De novo assembly and genome quality control were detailed in Supplementary Information (Supplementary Note 1 and 2; Supplementary Fig. 44). Gene models were predicted based on de novo prediction, homologous identification and Unigene clusters. Repeat elements were characterized using LTR-FINDER43 (link) and RepeatScout44 (link) and annotated using RepeatMasker45 with the parameter “-nolow -no_is -norna -engine wublast”.
Wang Z.H., Wang X.F., Lu T., Li M.R., Jiang P., Zhao J., Liu S.T., Fu X.Q., Wendel J.F., Van de Peer Y., Liu B, & Li L.F. (2022). Reshuffling of the ancestral core-eudicot genome shaped chromatin topology and epigenetic modification in Panax. Nature Communications, 13, 1902.
Full text: Click here
Publication 2022
Chromium DNA Library Genome Ginseng Panax ginseng
4
De novo Chloroplast Genome Assembly
Cited 5 times
Assembly of complete cp genome and nrDNA sequences was performed by de novo assembly of the low coverage whole genome sequence (WGS) via a bioinformatics pipeline (http://phyzen.com). Briefly, trimmed reads with Phred scores of 20 or less were prepared from the total pair-end (PE) raw reads using the CLC-quality trim tool and then were assembled by a CLC genome assembler (ver. 4.06 beta, CLC Inc, Rarhus, Denmark) with parameters of minimum 200 to 600 bp autonomously controlled overlap size. The principal contigs representing the cp genome were retrieved from the total contigs using MUMmer [18 (link)] with the cp genome sequence of Panax ginseng cv. ChP (KM088019) as reference sequence. The representative cp contigs were arranged in order based on the previously reported cp genome sequence and connected into a single draft sequence by joining overlapping terminal sequences. Assembly errors were identified in the initial assembly contigs and manually corrected by mapping of raw reads to assembled sequences. Error correction was validated by nucleotide sequencing after PCR amplification.
Kim K., Lee S.C., Lee J., Lee H.O., Joh H.J., Kim N.H., Park H.S, & Yang T.J. (2015). Comprehensive Survey of Genetic Diversity in Chloroplast Genomes and 45S nrDNAs within Panax ginseng Species. PLoS ONE, 10(6), e0117159.
Full text: Click here
Publication 2015
Genome Panax ginseng
5
Eudicot Chloroplast Genome Primers
Cited 5 times
The cpDNA sequences of five eudicot plant species namely Nicotiana tabacum (NC_001879), Arabidopsis thaliana (NC_000932), Atropa belladonna (NC_004561), Spinacea oleracea (NC_002202) and Panax ginseng (NC_006290) were aligned using ClustalW [36 ]. Tobacco chloroplast genome sequence was used as a reference and its coding regions were delineated in the aligned sequences. Highly conserved, putative primer sites were derived by hand parsing the aligned sequences of the IR B region. Primer candidates satisfied several criteria. A candidate primer must be resident to the coding region or conserved intergenic region and primer pairs must be spaced by ~1.0 to 1.2 kb. The primers must share 95% sequence identity among the representative plastid genomes. For universal, large-format application in simultaneous PCR reactions the primers should maintain approximately 50% GC content and a Tm of approximately 50°C. Table 1 lists the primer sequences, annealing sites, respective position in tobacco, Arabidopsis and maize plastid genomes and the expected amplicon sizes. This set of primers, used to amplify the large IR region in this manuscript, will be supplied by the authors upon request.
Dhingra A, & Folta K.M. (2005). ASAP: Amplification, sequencing & annotation of plastomes. BMC Genomics, 6, 176.
Full text: Click here
Publication 2005
Arabidopsis Arabidopsis thalianas Belladonna Chloroplast DNA Genome, Chloroplast Genome, Plastid Intergenic Region Maize Nicotiana Nicotiana tabacum Oligonucleotide Primers Panax ginseng Plants Spinacia oleracea

Most recents protocols related to «Panax ginseng»

1
Multipurpose Chinese Herbal Formulation
DHJSD comprised 6 g each of Radix glycyrrhizae, Panax ginseng, Radix achyranthis bidentatae, Eucommiae ulmoidis cortex, Poria cocos, Cortex cinnamomi, Radix paeoniae alba, Radix rehmanniae, Radix angelicae sinensis, Rhizoma chuanxiong, Herba Asari, Radix saposhnikoviae, Radix gentianae macrophyllae, Ramulus loranthi and 9 g of Radix angelicae pubescentis. The above-mentioned herbs were provided by the First Hospital of Wuhan. The specific preparation method of DHJSD has been previously reported [28 (link)]. It was formulated by the Pharmacy Department of the Wuhan First Hospital to contain 1 g/mL of crude drug. The stock solution was cooled at room temperature and stored at 4 °C prior to usage. In subsequent experiments, we diluted the DHJSD stock solution to ultimate contents of 500, 400, 300, 200 and 100 μg/mL, adopting DMEM/F12 medium with 15% fetal bovine serum (FBS).
Liu W., Zhao X, & Wu X. (2023). Duhuo Jisheng Decoction suppresses apoptosis and mitochondrial dysfunction in human nucleus pulposus cells by miR-494/SIRT3/mitophagy signal axis. Journal of Orthopaedic Surgery and Research, 18, 177.
Full text: Click here
Publication 2023
cinnamomi cortex Cortex, Cerebral Panax ginseng Pharmaceutical Preparations Plant Roots radix gentianae macrophyllae Rhizome sheng-di-huang Wolfiporia extensa
2
Herbal Compound SLBZS Preparation
SLBZS is composed of Panax Ginseng, Wolfiporia cocos, Atractylodes macrocephala, Dioscorea opposita, Dolichos Lablab, Semen Nelumbinis, Semen Coicis, Fructus Amomi, Platycodon grandiflorus and Glycyrrhiza uralensis Fisch, all herbs were purchased from Beijing Tongrentang Guangzhou pharmaceutical chain Co., Ltd (Guangzhou, China). Panax Ginseng, Wolfiporia cocos, Atractylodes macrocephala, Dioscorea opposita, Dolichos Lablab, Semen Nelumbinis, Semen Coicis, Fructus Amomi, Platycodon grandiflorus and Glycyrrhiza uralensis Fisch at a ratio of 4:4:4:4:3:2:2:2:2:4, pulverize in a beater and pass through a sieve of 60 mesh (19 (link), 20 (link), 22 (link)). 10g SLBZS powder was accurately weighed in a 250 ml conical flask, and 4% (corn flour by weight/substrate by weight) of corn flour was added to it. High-temperature sterilization was performed at 121°C for 20 min, and cooling to room temperature for later use.
Lv W., Ma Y., Zhang Y., Wang T., Huang J., He S., Du H, & Guo S. (2023). Effects of Lactobacillus plantarum fermented Shenling Baizhu San on gut microbiota, antioxidant capacity, and intestinal barrier function of yellow-plumed broilers. Frontiers in Veterinary Science, 10, 1103023.
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Publication 2023
Atractylodes Balloon Flower Corn Flour Dioscorea opposita Dolichos Fever Fruit Glycyrrhiza uralensis Panax ginseng Pharmaceutical Preparations Plant Embryos Powder Sterilization Wolfiporia extensa
3
Preparation and Characterization of Yinhuangyan Decoction
YYD consists of Panax Ginseng C. A. Mey (PG, Ren Shen, 12 g), Polygonati Rhizoma (PR, Huang Jing, 15 g), Ophiopogon Japonicus (OJ, Mai Dong, 15 g), Lilii Bulbus (LB, Bai He, 30 g), Adenophorae Ae Radix (AAR, Nan Sha Shen, 15 g), Trichosanthis Radix (TR, Tian Hua Fen, 15 g), and Agrimonia Eupatoria (AE, Xian He Cao, 30 g). To prepare YYD, all crude herbs were soaked in 10 volumes of distilled water for 30 min and then were decocted for 1 h for 2 times. The herbal extract was centrifuged at 1000 rpm for 30 min to collect the supernatant. The extraction procedure was repeated two times. Then, the supernatants were mixed and evaporated to obtain a powder. Finally, the dry powder was dissolved in DMSO to 125 mg/mL, filtered with a 0.22 μm filter, and reserved at −20°C. The mass spectra of YYD were performed and established for quality control.
Jiao P., Wang Y., Ren G., Chu D., Li Y, & Sang T. (2023). Integrating Network Pharmacology and Experimental Validation to Elucidate the Mechanism of Yiqi Yangyin Decoction in Suppressing Non-Small-Cell Lung Cancer. BioMed Research International, 2023, 4967544.
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Publication 2023
Agrimonia eupatoria Mass Spectrometry Medulla Oblongata Ophiopogon japonicus Panax ginseng Plant Roots Powder Rhizome Sulfoxide, Dimethyl Tian-hua-fen
4
Standardized Extraction of YQF Components
YQF consists of Panax ginseng C.A.Mey (Renshen), Coptis chinensis Franch (Huanglian), and Ligusticum chuanxiong S.H.Qiu, Y.Q.Zeng, K.Y.Pan, Y.C.Tang and J.M.Xu (Chuanxiong). These herbs were purchased from Hebei Baicao Kangshen Pharmaceutical Co., Ltd., (Hebei, China). Donepezil hydrochloride (production lot No. 2104113; Shenzhen Anlixin, Shenzhen, China) was purchased from Eisai (Tokyo, Japan). Ginsenosides Rg1 reference substance, purity 99.70% (A0237); ginsenosides Re reference substance, purity 99.52% (A0244); ginsenosides Rd reference substance, purity 98.55% (A0245); ginsenosides Rb1 reference substance, purity 98.58% (A0234); ferulic acid reference substance, purity 99.32% (A0050); provided by Chengdu Desite Biotechnology Co., Ltd., Chengdu, China. Ginsenosides Rh2 reference substance, purity 98% (B21729); Ginsenosides Rg2 reference substance, purity 98% (B21727); epiberberine reference substance, purity 98% (B20108); coptisine chloride reference substance, purity 98% (B21438); palmatine reference substance, purity 98% (B21646);berberine reference substance, purity 98% (B21379); and provided by Shanghai Yuanye Biotechnology Co., Ltd., Shanghai, China.
Wei W., Pei H., Ma L.N., Zheng R., Huang Q.Y., Chang S.R., Cao Y, & Li H. (2023). Comparison of Yizhiqingxin formula extraction methods and their pharmacodynamic differences. Frontiers in Neuroscience, 17, 1097859.
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Publication 2023
Berberine Coptis chinensis coptisine chloride Donepezil Hydrochloride epiberberine ferulic acid ginsenoside Rb1 ginsenoside Rd ginsenoside Re ginsenoside Rg1 ginsenoside Rg2 ginsenoside Rh2 huanglian Lovage, Alpine palmatine Panax ginseng Pharmaceutical Preparations
5
HPLC Analysis of Panax Ginseng, Coptis Chinensis, and Ligusticum Chuanxiong in YQF Powder
The reference standards or YQF powder were precisely weighed and dissolved with methanol solution. Inertsil C18 (150 mm × 4.6 mm, 5 μm) was used as the stationary phase for the chromatographic separation. The compounds were identified by individual peak retention times compared to reference substances. The detection wavelength of the main components of Panax ginseng C.A.Mey (Renshen) in YQF was 203 nm, with a column temperature at 35°C. The flow rate was 1 ml/min and the total injection volume was 20 μL. The mobile phase consisted of solvent A (acetonitrile) and solvent B (water) with the following gradient elution: 18% A at 0–40 min; 21% A at 40–42 min; 26% A at 42–46 min; 32% A at 46–66 min; 33.5% A at 66–71 min; 38% A at 71–86 min; 65% A at 86–96 min; 85% A at 96–103 min (Guo, 2014 ). The detection wavelength of the main components of Coptis chinensis Franch (Huanglian) in YQF was 345 nm, with a column temperature at 25°C. The flow rate was 1 mL/min, and the total injection volume was 5 μL. The mobile phase consisted of 70% solvent A (0.05% trifluoroacetic acid) and 30% solvent B (acetonitrile). The detection wavelength of the main components of Ligusticum chuanxiong S.H.Qiu, Y.Q.Zeng, K.Y.Pan, Y.C.Tang and J.M.Xu (Chuanxiong) in YQF was 294 nm, with a column temperature at 30°C. The flow rate was 1 mL/min, and the total injection volume was 5 μL. The mobile phase consisted of 60% solvent A (0.05% trifluoroacetic acid) and 40% solvent B (methanol).
Wei W., Pei H., Ma L.N., Zheng R., Huang Q.Y., Chang S.R., Cao Y, & Li H. (2023). Comparison of Yizhiqingxin formula extraction methods and their pharmacodynamic differences. Frontiers in Neuroscience, 17, 1097859.
Full text: Click here
Publication 2023
acetonitrile Chromatography Coptis chinensis huanglian Lovage, Alpine Methanol Panax ginseng Powder Retention (Psychology) Solvents Trifluoroacetic Acid

Top products related to «Panax ginseng»

1
Fetal bovine serum (fbs) by Thermo Fisher Scientific
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Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
2
Dimethyl sulfoxide (dmso) by Merck Group
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DMSO is a versatile organic solvent commonly used in laboratory settings. It has a high boiling point, low viscosity, and the ability to dissolve a wide range of polar and non-polar compounds. DMSO's core function is as a solvent, allowing for the effective dissolution and handling of various chemical substances during research and experimentation.
3
Acetonitrile by Merck Group
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4
Methanol by Merck Group
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Methanol is a clear, colorless, and flammable liquid that is widely used in various industrial and laboratory applications. It serves as a solvent, fuel, and chemical intermediate. Methanol has a simple chemical formula of CH3OH and a boiling point of 64.7°C. It is a versatile compound that is widely used in the production of other chemicals, as well as in the fuel industry.
5
Penicillin by Thermo Fisher Scientific
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Penicillin is a type of antibiotic used in laboratory settings. It is a broad-spectrum antimicrobial agent effective against a variety of bacteria. Penicillin functions by disrupting the bacterial cell wall, leading to cell death.
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Tri reagent by Molecular Research Center
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TRI Reagent is a phenol-based reagent used for the isolation of total RNA, DNA, and proteins from a variety of biological samples. It is a single-step method that can be used to extract high-quality nucleic acids and proteins from cells and tissues.
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Ammonium formate by Merck Group
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Ammonium formate is a chemical compound that is commonly used in various laboratory applications. It is a crystalline solid that is soluble in water and other polar solvents. Ammonium formate serves as a buffer in analytical techniques and is also used as a mobile phase additive in liquid chromatography.
8
Ki16425 by Cayman Chemical
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Ki16425 is a chemical compound that is a selective antagonist for the CB1 cannabinoid receptor. It is commonly used in research applications to study the role of the endocannabinoid system in various biological processes.
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Rpmi 1640 medium by Thermo Fisher Scientific
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RPMI 1640 medium is a commonly used cell culture medium developed at Roswell Park Memorial Institute. It is a balanced salt solution that provides essential nutrients, vitamins, and amino acids to support the growth and maintenance of a variety of cell types in vitro.
10
Polygalacturonase from aspergillus aculeatus by Megazyme
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Polygalacturonase from Aspergillus aculeatus is an enzyme that catalyzes the hydrolysis of polygalacturonic acid, a major component of plant cell walls. It is a pectinolytic enzyme used in various industrial applications.

More about "Panax ginseng"

Panax ginseng, also known as Asian ginseng or Korean ginseng, is a perennial plant native to the mountainous regions of Asia.
This adaptogenic herb has been a staple in traditional Chinese and Korean medicine for centuries, prized for its potential health benefits.
The active compounds in Panax ginseng, such as ginsenosides, are believed to have a wide range of effects on the human body, including potential cognitive enhancement, immune system support, and stress management.
Researchers have been exploring the applications of this botanical in various areas of human health and wellness.
In addition to Panax ginseng, other compounds and materials may be used in research related to this herb.
For example, FBS (Fetal Bovine Serum) and RPMI 1640 medium are commonly used in cell culture experiments, while solvents like DMSO, acetonitrile, and methanol may be employed for extraction and analysis.
Enzymes like polygalacturonase from Aspergillus aculeatus can also play a role in ginseng research.
To optimize your Panax ginseng studies, the PubCompare.ai platform can be a valuable tool.
This AI-driven system helps researchers locate the best protocols from literature, preprints, and patents, while utilizing intelligent comparisons to enhance reproducibility and accuracy.
By unlocking the power of AI-driven insights, you can deepen your understanding of this fascinating botanical and uncover new avenues for exploration.
Whether you're investigating the cognitive effects of Panax ginseng, its potential for immune system support, or its role in stress management, the PubCompare.ai platform can be a game-changer in your research endeavors.
Embark on your Panax ginseng journey with confidence, armed with the latest AI-powered insights and a comprehensive understanding of this remarkable adaptogenic herb.