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Japanese

Japanese: A collective term for the ethnic group originating in the Japanese archipelago and constituting the majority of the population of Japan.
The Japanese language is a Japonic language that is unrelated to the Sino-Tibetan, Altaic, or any other language famly.
The Japanese people have a rich cultural hertage, including unique traditions, cuisine, and art forms.

Most cited protocols related to «Japanese»

1
Nationwide Birth Cohort Recruitment
Cited 146 times
To ensure generalizability and ability to extrapolate the results of JECS to Japanese population, the 15 Regional Centers are selected to cover wide geographical areas. The study locations’ urbanization and land development are diverse, from urban and suburban to rural areas as well as from agricultural and fishery to commercial and industrial uses.
Regional Centers were selected in a competitive process in which universities and other research institutions were invited to submit proposals for covered areas and population, recruitment methods, organization structures, regional liaison, and the resources. Each Regional Center consists of one or more study areas. The population of the selected study areas is 130,000 to 600,000. Assuming birth rate of the study areas to be 1%, each Regional Center will see 1,300 to 6,000 annual births, 4,400 on average. JECS aims half of all the births in the area to be covered. Selected Regional Centers are required to recruit 3,000 to 9,000 pregnant women in three years, totaling to 100,000 participants in 15 Regional Centers (Figure 1). In order to ensure the maximum contact with eligible participants, Regional Centers have formed JECS regional liaison involving local governments and health care providers. All the study areas are contained within administrative units, e.g. municipalities, further enhancing local government cooperation. This makes it easier to obtain basic health statistics in the study areas, for example, total number of births, sex ratios, birth weights, morbidities, and mortalities. It also helps us maximize follow-up and retention rates.
Kawamoto T., Nitta H., Murata K., Toda E., Tsukamoto N., Hasegawa M., Yamagata Z., Kayama F., Kishi R., Ohya Y., Saito H., Sago H., Okuyama M., Ogata T., Yokoya S., Koresawa Y., Shibata Y., Nakayama S., Michikawa T., Takeuchi A, & Satoh H. (2014). Rationale and study design of the Japan environment and children’s study (JECS). BMC Public Health, 14, 25.
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Publication 2014
Japanese Pregnant Women Retention (Psychology) Urbanization
2
JCOG Surgical Complications Criteria
Cited 103 times
The Japan Clinical Oncology Group (JCOG) commissioned a committee to establish more precise criteria for the grading of surgical complications. The committee comprised members from nine JCOG study groups (gastric, esophageal, colorectal, lung, breast, gynecologic, urologic, bone and soft tissue, and brain) who have extensive experience with surgical trials. These groups established the JCOG postoperative complications criteria (JCOG PC criteria). Members identified the postoperative complications experienced commonly in their fields and defined detailed grades for each complication in accordance with the general grading rules of the Clavien-Dindo classification. The JCOG PC criteria were reviewed and approved by the JCOG Executive Committee and published on the JCOG website in October, 2011 (in Japanese) [8 ].
Katayama H., Kurokawa Y., Nakamura K., Ito H., Kanemitsu Y., Masuda N., Tsubosa Y., Satoh T., Yokomizo A., Fukuda H, & Sasako M. (2015). Extended Clavien-Dindo classification of surgical complications: Japan Clinical Oncology Group postoperative complications criteria. Surgery Today, 46, 668-685.
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Publication 2015
Bones Brain Breast Committee Members Japanese Lung Neoplasms Operative Surgical Procedures Postoperative Complications Stomach Tissues
3
Evaluating Hospital Data Integration in Japan
Cited 88 times
In Japan, the DPC-based lump-sum payment system was introduced in acute-care hospitals nationwide from 2003.24 (link) The DPC data used for payments include patient demographics and selected clinical information, admission and discharge statuses, diagnoses, surgeries and procedures performed, medications, and special reimbursements for specific conditions. Diagnoses are recorded using International Classification of Diseases, Tenth Revision (ICD-10) codes by the attending physicians. Suspected diagnoses are allowed to be recorded, but are designated as such. There are six categories of diagnoses, each with a limited number of recordable diseases. One diagnosis each is coded for “main diagnosis”, “admission-precipitating diagnosis”, “most resource-consuming diagnosis”, and “second most resource-consuming diagnosis”. A maximum of four diagnoses each can be coded for “comorbidities present at time of admission” and “conditions arising after admission”. All procedures performed during hospitalization are recorded according to the Japanese fee schedule for reimbursement.
The NHO was established in 2004 to take over the management of the national hospitals. As of October 2014, there were 143 hospitals nationwide run by the NHO, including both general acute-care hospitals and specialized long-term-care hospitals. Fifty-four hospitals from 35 prefectures had implemented the DPC-based payment system, and the mean number of acute-care beds in these 54 hospitals was 410 (range, 135–730). All NHO hospitals provide administrative claims data to the Medical Information Analysis (MIA) databank, which is managed by the Clinical Research Center at NHO Headquarters. In NHO hospitals with implementation of the DPC-based payment system, the DPC data are also stored in the MIA databank. In addition, the NHO preliminarily introduced the SS-MIX standardized storage23 (link) to its hospitals in 2013. The SS-MIX storage enables medical chart information from different vendors, including daily laboratory data, to be recorded in a standardized manner. In the SS-MIX storage, laboratory data are specified using JLAC-10 codes. The flow of data is shown in Fig. 1.

Flow of data in the National Hospital Organization. DPC, Diagnosis Procedure Combination; MIA, Medical Information Analysis; NHO, National Hospital Organization; SS-MIX, Standardized Structured Medical Record Information Exchange.

Fig. 1We conducted the present study on patients admitted to four acute-care NHO hospitals with implementation of both the DPC-based payment system and SS-MIX storage. The four hospitals were a 380-bed hospital in Shizuoka Prefecture, a 280-bed hospital in Kochi Prefecture, a 380-bed hospital in Fukuoka Prefecture, and a 420-bed hospital in Saga Prefecture. Laboratory data collected from the SS-MIX storage at each hospital and DPC data extracted from the MIA databank were compared with chart review results.
Yamana H., Moriwaki M., Horiguchi H., Kodan M., Fushimi K, & Yasunaga H. (2017). Validity of diagnoses, procedures, and laboratory data in Japanese administrative data. Journal of Epidemiology, 27(10), 476-482.
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Publication 2017
Diagnosis Health Information Exchange Hospital Administration Hospitalization Japanese Long-Term Care Operative Surgical Procedures Patient Discharge Patients Pharmaceutical Preparations Physicians Tests, Diagnostic
4
Development and Validation of Short-Form FFQ
Cited 72 times
The long-FFQ consisted of 172 food and beverage items and nine frequency categories, ranging from almost never to seven or more times per day (or to 10 or more glasses per day, for beverages). It asked about the usual consumption of listed foods during the previous year. The food list was initially developed according to percentage contributions based on absolute values of energy and intake of 14 target nutrients from weighed food records in 1989–19918 (link) and used for the Japan Public Health Center-based prospective Study,8 (link)–12 (link) for which it was modified for middle-aged and elderly residents in a wide variety of areas of Japan. With regard to this modification, the following criteria were considered: calculation for an additional 17 nutrient items, such as fiber and folate, change of foods contributing to the absolute nutrient intake according to the updated Standard Tables of Food Composition in Japan,13 ,14 and dietary regionality and change in generation for the present cohort (data not shown). As a result, 33 foods were added, and 5 foods and beverages were excluded.15 (link) Moreover, six foods were also added to account for potential inter-individual variation in specific nutrients, such as isothiocyanate and isoflavone. With regard to alcoholic beverages, choices of intake amount were changed from the initial JPHC-FFQ.
To develop the food list for the short-FFQ, we selected and combined items and supporting questions from the original long-FFQ. We selected the three major foods and beverages that contributed to inter-individual variation for each of 40 nutrients according to a cumulative R2 for the 40 nutrients,16 based on the multiple regression coefficient with total intake of a specific nutrient as the dependent variable and its intake from each food as the explanatory variable. Inter-individual variation was calculated by gender among 45 869 men and 52 989 women who responded to the JPHC Study 10-year follow-up survey. Consequently, cumulative R2 for the nutrients ranged from 0.4 to 1.0. For potential inter-individual variation in intake of specific food groups, some foods, such as coffee, were added. Ultimately, 66 food and beverage items were selected for the short-FFQ. In this validation study, information on alcoholic beverages was substituted with those from the long-FFQ (united with overall information of lifestyle), because these questions were not included in the short-FFQ. This was because information on alcoholic beverage intake was structured in pages for lifestyle other than diet, such as smoking status and physical activity, and the reproducibility of alcoholic beverage intake was relatively high even if questionnaires were administered at a 1-year interval.17 (link),18 (link)Intakes of energy, 53 nutrients, and 29 food groups were calculated using the Standard Tables of Food Composition in Japan 2010,19 Standard Tables of Food Composition in Japan Fifth Revised and Enlarged Edition 2005 For Fatty Acids,20 and a specifically developed food composition table for isoflavones in Japanese foods.21 (link)
Validity of Short and Long Self-Administered Food Frequency Questionnaires in Ranking Dietary Intake in Middle-Aged and Elderly Japanese in the Japan Public Health Center-Based Prospective Study for the Next Generation (JPHC-NEXT) Protocol Area. (2016). Journal of Epidemiology, 26(8), 420-432.
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Publication 2016
Aged Alcoholic Beverages Beverages Coffee Diet Eating Eyeglasses Fatty Acids Fibrosis Folate Food Isoflavones isothiocyanate Japanese Nutrient Intake Nutrients Woman
5
Preprocessing HapMap Phase 3 Genotypes
Cited 70 times
The HapMap phase 3 dataset consists of 1184 human individuals across 11 populations (ASW: African ancestry in Southwest USA; CEU: Utah residents with Northern and Western European ancestry from the CEPH collection; CHB: Han Chinese in Beijing, China; CHD: Chinese in Metropolitan Denver, Colorado; GIH: Gujarati Indians in Houston, Texas; JPT: Japanese in Tokyo, Japan; LWK: Luhya in Webuye, Kenya; MEX: Mexican ancestry in Los Angeles, California; MKK: Maasai in Kinyawa, Kenya; TSI: Toscani in Italia; YRI: Yoruba in Ibadan, Nigeria) assayed for 1,440,616 SNPs [6] (link). We performed QC on the data, including removal of SNPs with MAF , missingness , and deviation from Hardy-Weinberg equilibrium . We removed non-founders and individuals with genotyping missingness , leaving 957 individuals. Next, we removed several regions of high LD and/or known inversions (chr5∶44 Mb–51.5 Mb, chr6∶25 Mb–33.5 Mb, chr8∶8 Mb–12 Mb, chr11∶45 Mb–57 Mb) [15] (link). Finally, we used PLINK [16] (link) –indep-pairwise 1000 10 0.02 to thin the SNPs by LD ( ), leaving 14,389 SNPs.
Abraham G, & Inouye M. (2014). Fast Principal Component Analysis of Large-Scale Genome-Wide Data. PLoS ONE, 9(4), e93766.
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Publication 2014
Chinese Europeans HapMap Homo sapiens Inversion, Chromosome Japanese Negroid Races Population Group Single Nucleotide Polymorphism

Most recents protocols related to «Japanese»

1
Synthesis and Surface Modification of Hydrotalcite Particles
Not available on PMC !

Example 1

In a 2 L stainless steel container, 730 g of aluminum hydroxide powder (commercially available from KANTO CHEMICAL CO., INC., Cica special grade) were added into 1110 mL of 48% sodium hydroxide solution (commercially available from KANTO CHEMICAL CO., INC., Cica special grade), and they were stirred at 124° C. for 1 hour to give a sodium aluminate solution (First Step).

After the sodium aluminate solution was cooled to 80° C., ion exchange water was added into the sodium aluminate solution to achieve a total amount of 1500 mL.

After 96 mL of the sodium aluminate solution were separated into a 1 L stainless steel container, pure water was added into the solution to achieve a total amount of 730 mL (concentration of the sodium aluminate solution: 0.8 mol/L). The solution was stirred with keeping a temperature thereof at 25° C., and the solution was aerated with carbon dioxide in an aeration amount of 0.7 L/min. for 60 minutes to give adjusted aluminum hydroxide slurry (low-crystallinity aluminum compound=pseudo-boehmite) (Second Step).

Separately, 49.5 g of magnesium oxide powder (commercially available from KANTO CHEMICAL CO., INC., special grade) were added to 327 mL of pure water, and they were stirred for 1 hour to give magnesium oxide slurry.

In a 1.5 L stainless steel container, the magnesium oxide slurry and the adjusted aluminum hydroxide slurry were added into 257 mL of pure water, and they were stirred at 55° C. for 90 minutes to cause a first-order reaction. As a result, a reactant containing hydrotalcite nuclear particles was prepared (Third Step).

Then, pure water was added to the reactant to give a solution in a total amount of 1 L. The solution was put into a 2 L autoclave, and a hydrothermal synthesis was performed at 160° C. for 7 hours. As a result, hydrotalcite particles slurry was synthesized (Fourth Step).

To the hydrotalcite particles slurry were added 4.3 g of stearic acid (3 parts by mass with respect to 100 parts by mass of hydrotalcite particles) with keeping a temperature of the hydrotalcite particles slurry at 95° C. to perform a surface treatment on particles (Fifth Step). After the hydrotalcite particles slurry of which particles were surface treated was filtered and washed, a drying treatment was performed at 100° C. to give solid products of hydrotalcite particles. The produced hydrotalcite particles were subjected to an elemental analysis, resulting in that Mg/Al (molar ratio)=2.1.

In accordance with a method of Example 1 described in Japanese Laid-Open Patent Publication No. 2003-048712, hydrotalcite particles were synthesized.

In 150 g/L of NaOH solution in an amount of 3 L were dissolved 90 g of metal aluminum to give a solution. After 399 g of MgO were added to the solution, 174 g of Na2CO3 were added thereto and they were reacted with each other for 6 hours with stirring at 95° C. As a result, hydrotalcite particles slurry was synthesized.

To the hydrotalcite particles slurry were added 30 g of stearic acid (3 parts by mass with respect to 100 parts by mass of hydrotalcite particles) with keeping a temperature of the hydrotalcite particles slurry at 95° C. to perform a surface treatment on particles. After the hydrotalcite particles slurry of which particles were surface treated was cooled, filtered and washed to give solid matters, a drying treatment was performed on the solid matters at 100° C. to give solid products of hydrotalcite particles.

Example 2

In a 2 L stainless steel container, 730 g of aluminum hydroxide powder (commercially available from KANTO CHEMICAL CO., INC., Cica special grade) were added into 1110 mL of 48% sodium hydroxide solution (commercially available from KANTO CHEMICAL CO., INC., Cica special grade), and they were stirred at 124° C. for 1 hour to give a sodium aluminate solution (First Step).

After the sodium aluminate solution was cooled to 80° C., ion exchange water was added into the sodium aluminate solution to achieve a total amount of 1500 mL.

After 96 mL of the sodium aluminate solution were separated into a 1 L stainless steel container, pure water was added into the solution to achieve a total amount of 730 mL (concentration of the sodium aluminate solution: 0.8 mol/L). The solution was stirred with keeping a temperature thereof at 30° C., and the solution was aerated with carbon dioxide in an aeration amount of 0.7 L/min. for 90 minutes to give adjusted aluminum hydroxide slurry (low-crystallinity aluminum compound=pseudo-boehmite) (Second Step).

Separately, 49.5 g of magnesium oxide powder (commercially available from KANTO CHEMICAL CO., INC., special grade) were added to 327 mL of pure water, and they were stirred for 1 hour to give magnesium oxide slurry.

In a 1.5 L stainless steel container, the magnesium oxide slurry and the adjusted aluminum hydroxide slurry were added into 257 mL of pure water, and they were stirred at 55° C. for 90 minutes to cause a first-order reaction. As a result, a reactant containing hydrotalcite nuclear particles was prepared (Third Step).

Then, pure water was added to the reactant to give a solution in a total amount of 1 L. The solution was put into a 2 L autoclave, and a hydrothermal synthesis was performed at 160° C. for 7 hours. As a result, hydrotalcite particles slurry was synthesized (Fourth Step).

To the hydrotalcite particles slurry were added 4.3 g of stearic acid (3 parts by mass with respect to 100 parts by mass of hydrotalcite particles) with keeping a temperature of the hydrotalcite particles slurry at 95° C. to perform a surface treatment on particles (Fifth Step). After the hydrotalcite particles slurry of which particles were surface treated was filtered and washed, a drying treatment was performed at 100° C. to give solid products of hydrotalcite particles.

Solid products of hydrotalcite particles were produced in a same manner as in Comparative Example 1 except that reaction conditions of 95° C. and 6 hours for synthesis of the hydrotalcite particles slurry in Comparative Example 1 were changed to hydrothermal reaction conditions of 170° C. and 6 hours.

Example 3

In a 2 L stainless steel container, 730 g of aluminum hydroxide powder (commercially available from KANTO CHEMICAL CO., INC., Cica special grade) were added into 1110 mL of 48% sodium hydroxide solution (commercially available from KANTO CHEMICAL CO., INC., Cica special grade), and they were stirred at 124° C. for 1 hour to give a sodium aluminate solution (First Step).

After the sodium aluminate solution was cooled to 80° C., ion exchange water was added into the sodium aluminate solution to achieve a total amount of 1500 mL.

After 96 mL of the sodium aluminate solution were separated into a 1 L stainless steel container, pure water was added into the solution to achieve a total amount of 730 mL (concentration of the sodium aluminate solution: 0.8 mol/L). The solution was stirred with keeping a temperature thereof at 60° C., and the solution was aerated with carbon dioxide in an aeration amount of 0.7 L/min. for 60 minutes to give adjusted aluminum hydroxide slurry (low-crystallinity aluminum compound=pseudo-boehmite) (Second Step).

Separately, 49.5 g of magnesium oxide powder (commercially available from KANTO CHEMICAL CO., INC., special grade) were added to 327 mL of pure water, and they were stirred for 1 hour to give magnesium oxide slurry.

In a 1.5 L stainless steel container, the magnesium oxide slurry and the adjusted aluminum hydroxide slurry were added into 257 mL of pure water, and they were stirred at 55° C. for 90 minutes to cause a first-order reaction. As a result, a reactant containing hydrotalcite nuclear particles was prepared (Third Step).

Then, pure water was added to the reactant to give a solution in a total amount of 1 L. The solution was put into a 2 L autoclave, and a hydrothermal synthesis was performed at 160° C. for 7 hours. As a result, hydrotalcite particles slurry was synthesized (Fourth Step).

To the hydrotalcite particles slurry were added 4.3 g of stearic acid (3 parts by mass with respect to 100 parts by mass of hydrotalcite particles) with keeping a temperature of the hydrotalcite particles slurry at 95° C. to perform a surface treatment on particles (Fifth Step). After the hydrotalcite particles slurry of which particles were surface treated was filtered and washed, a drying treatment was performed at 100° C. to give solid products of hydrotalcite particles.

In accordance with a method of Example 1 described in Japanese Laid-Open Patent Publication No. 2013-103854, hydrotalcite particles were synthesized.

Into a 5 L container were added 447.3 g of magnesium hydroxide (d50=4.0 μm) and 299.2 g of aluminum hydroxide (d50=8.0 μm), and water was added thereto to achieve a total amount of 3 L. They were stirred for 10 minutes to prepare slurry. The slurry had physical properties of d50=10 μm and d90=75 μm. Then, the slurry was subjected to wet grinding for 18 minutes (residence time) by using Dinomill MULTILAB (wet grinding apparatus) with controlling a slurry temperature during grinding by using a cooling unit so as not to exceed 40° C. As a result, ground slurry had physical properties of d50=1.0 μm, d90=3.5 μm, and slurry viscosity=5000 cP. Then, sodium hydrogen carbonate was added to 2 L of the ground slurry such that an amount of the sodium hydrogen carbonate was ½ mole with respect to 1 mole of the magnesium hydroxide. Water was added thereto to achieve a total amount of 8 L, and they were stirred for 10 minutes to give slurry. Into an autoclave was put 3 L of the slurry, and a hydrothermal reaction was caused at 170° C. for 2 hours. As a result, hydrotalcite particles slurry was synthesized.

To the hydrotalcite particles slum were added 6.8 g of stearic acid (3 parts by mass with respect to 100 parts by mass of hydrotalcite particles) with keeping a temperature of the hydrotalcite particles slurry at 95° C. to perform a surface treatment on particles. After solids were filtered by filtration, the filtrated cake was washed with 9 L of ion exchange water at 35° C. The filtrated cake was further washed with 100 mL of ion exchange water, and a conductance of water used for washing was measured. As a result, the conductance of this water was 50 μS/sm (25° C.). The water-washed cake was dried at 100° C. for 24 hours and was ground to give solid products of hydrotalcite particles.

Example 5

In a 2 L stainless steel container, 730 g of aluminum hydroxide powder (commercially available from KANTO CHEMICAL CO., INC., Cica special grade) were added into 1110 mL of 48% sodium hydroxide solution (commercially available from KANTO CHEMICAL CO., INC., Cica special grade), and they were stirred at 124° C. for 1 hour to give a sodium aluminate solution (First Step).

After the sodium aluminate solution was cooled to 80° C., ion exchange water was added into the sodium aluminate solution to achieve a total amount of 1500 mL.

After 192 mL of the sodium aluminate solution were separated into a 1 L stainless steel container, pure water was added into the solution to achieve a total amount of 730 mL (concentration of the sodium aluminate solution: 1.6 mol/L). The solution was stirred with keeping a temperature thereof at 30° C., and the solution was aerated with carbon dioxide in an aeration amount of 0.7 L/min. for 90 minutes to give adjusted aluminum hydroxide slurry (low-crystallinity aluminum compound=pseudo-boehmite) (Second Step).

Separately, 49.5 g of magnesium oxide powder (commercially available from KANTO CHEMICAL CO., INC., special grade) were added to 327 mL of pure water, and they were stirred for 1 hour to give magnesium oxide slurry.

In a 1.5 L stainless steel container, the magnesium oxide slurry and the adjusted aluminum hydroxide slurry were added into 257 mL of pure water, and they were stirred at 55° C. for 90 minutes to cause a first-order reaction. As a result, a reactant containing hydrotalcite nuclear particles was prepared (Third Step).

Then, pure water was added to the reactant to give a solution in a total amount of 1 L. The solution was put into a 2 L autoclave, and a hydrothermal synthesis was performed at 160° C. for 7 hours. As a result, hydrotalcite particles slurry was synthesized (Fourth Step).

To the hydrotalcite particles slurry were added 4.3 g of stearic acid (3 parts by mass with respect to 100 parts by mass of hydrotalcite particles) with keeping a temperature of the hydrotalcite particles slurry at 95° C. to perform a surface treatment on particles (Fifth Step). After the hydrotalcite particles slurry of which particles were surface treated was filtered and washed, a drying treatment was performed at 100° C. to give solid products of hydrotalcite particles.

In accordance with a method of Example 1 described in Japanese Laid-Open Patent Publication No. H06-136179, hydrotalcite particles were synthesized.

To 1 L of water were added 39.17 g of sodium hydroxide and 11.16 g of sodium carbonate with stirring, and they were heated to 40° C. Then, to 500 mL of distilled water were added 61.28 g of magnesium chloride (19.7% as MgO), 37.33 g of aluminum chloride (20.5% as Al2O3), and 2.84 g of ammonium chloride (31.5% as NH3) such that a molar ratio of Mg to Al, Mg/Al, was 2.0 and a molar ratio of NH3 to Al, NH3/Al, was 0.35. As a result, an aqueous solution A was prepared. The aqueous solution A was gradually poured into a reaction system of the sodium hydroxide and the sodium carbonate. The reaction system after pouring had pH of 10.2. Moreover, a reaction of the reaction system was caused at 90° C. for about 20 hours with stirring to give hydrotalcite particles slurry.

To the hydrotalcite particles slurry were added 1.1 g of stearic acid, and a surface treatment was performed on particles with stirring to give a reacted suspension. The reacted suspension was subjected to filtration and water washing, and then the reacted suspension was subjected to drying at 70° C. The dried suspension was ground by a compact sample mill to give solid products of hydrotalcite particles.

US11873230B2. Hydrotalcite particles, method for producing hydrotalcite particles, resin stabilizer containing hydrotalcite particles, and resin composition containing hydrotalcite particles (2024-01-16). TODA KOGYO CORP. [JP], SAKAI CHEMICAL INDUSTRY CO., LTD. [JP]. Inventors: Koji Kakuya [JP], Atsuko Yasunaga [JP], Nobukatsu Shigi [JP].
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Patent 2024
A-A-1 antibiotic Aluminum Aluminum Chloride aluminum oxide hydroxide Anabolism Bicarbonate, Sodium Carbon dioxide Chloride, Ammonium Filtration hydrotalcite Hydroxide, Aluminum Ion Exchange Japanese Magnesium Chloride Magnesium Hydroxide Molar Oxide, Magnesium Physical Processes Powder Resins, Plant sodium aluminate sodium carbonate Sodium Hydroxide Stainless Steel stearic acid Suby's G solution Viscosity
2
Synthesis and Characterization of Fluorinated Polymeric Compounds
Not available on PMC !

Example 1

Compound (3A) was obtained with reference to the method for producing compound (ii-2) described in WO2014/126064.
CF3 CF2—OCF2 CF2—(OCF2 CF2 CF2 CF2 OCF2 CF2)n—OCF2 CF2 CF2—C(O)NH—CH2 CH2 CH2—Si(OCH3)3  (3A)

Average of number n of units: 13, number average molecular weight of compound (3A): 4,920

Example 4

Compound (1-1C) was obtained in accordance with the method described in Preparation Example 15 of Japanese Patent No. 5761305.
CF3(OCF2 CF2)15(OCF2)16 OCF2 CH2 OCH2 CH2 CH2 Si[CH2 CH2 CH2 Si(OCH3)3]3  (1-1C)

Mn of compound (1-1C): 3,600

Example 8

In accordance with Example 4 in JP-A-2015 —199906, compound (1-3B) was obtained.

[Figure (not displayed)]

In the above formula (1-3B), p1:q≈47:53, p1+q1=43.

Mn of compound (1-3B): 4,800

US11873415B2. Substrate with water repellent oil repellent layer, vapor deposition material, and method for producing substrate with water repellent oil repellent layer (2024-01-16). AGC Inc. [JP]. Inventors: Yoshihito Tokunaga [JP], Maemi Iwahashi [JP], Kenji Ishizeki [JP], Hirokazu Kodaira [JP], Daisuke Kobayashi [JP], Asako Anazawa [JP], Yusuke Tomiyori [JP].
Full text: Click here
Patent 2024
Japanese
3
Formulation of EW-7197 Solution
Not available on PMC !

Example 8

The composition of the tested substance at each concentration is shown below.

EW-71970.1mM
Sodium chloride0.85g
Sodium dihydrogen phosphate dihydrate0.1g
(optionally) Benzalkonium chloride0.005g
Sodium hydroxidesuitable amount
Purified watersuitable amount
Total amount:100 mL (pH 7.0)

The concentration may be diluted using a base agent consisting of the following components.

Sodium chloride 0.85 g
Sodium dihydrogen phosphate dihydrate 0.1 g
(optionally) Benzalkonium chloride0.005 g
Sodium hydroxidesuitable amount
Purified watersuitable amount
Total amount100 mL (pH 7.0)

For example, commercially available components that are in compliance with the Japanese Pharmacopoeia or equivalent thereof can be used as each component other than the active ingredient.

US11857544B2. Composition or method including (t)ew-7197 for treating or preventing corneal endothelial diseases (2024-01-02). THE DOSHISHA [JP], SENJU PHARMACEUTICAL CO., LTD. [JP]. Inventors: Noriko Koizumi [JP], Naoki Okumura [JP], Mayumi Yamamoto [JP].
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Patent 2024
Chloride, Benzalkonium Chlorides EW-7197 Japanese Ophthalmic Solution Sodium Hydroxide sodium phosphate, monobasic
4
Evaluating Cytotoxicity of Compounds in Cancer Cells
Not available on PMC !

Example 5

The human skin squamous carcinoma line (HSC) (Japanese Collection of Research Bioresources Cell Bank (JCRB)) was cultured in Dulbecco's minimal essential media (DMEM) containing 20% fetal bovine serum (FBS), (Thermofisher, Waltham, MA). Cells were plated at a density of 5,000 cells per well into a 96-well plate and allowed to attach for 24 h in a 37° C. humidified incubator with a 5% CO2 atmosphere. Media was replaced with that containing test agents or vehicle (0.1% dimethylsulphoxide) in 1% FBS and cells incubated for a further 72 h. Cell viability was assessed using CellTiter-Glo® (Promega). Non-linear regression analysis was performed using GraphPad PRISM®. FIG. 5 shows a representative experiment where the EC50 of COMPOUND A, was 5.2 nM and that of COMPOUND G was 9.2 nM.

US11865113B2. Methods of treating a patient afflicted with non-alcoholic steatohepatitis (NASH) (2024-01-09). Lipidio Pharmaceuticals Inc. [US]. Inventors: Nigel R. A. Beeley [US], J. Gordon Foulkes [US], Kieran George Mooney [US], Charles Rodney Greenaway Evans [GB], Keith Arthur Johnson [US], Howard G. Welgus [US], Celia P. Jenkinson [US].
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Patent 2024
Atmosphere Carcinoma Cells Cell Survival Culture Media Cytotoxin Fetal Bovine Serum Homo sapiens inhibitors Japanese prisma Promega Skin Squamous Cell Carcinoma Squamous Epithelial Cells Sulfoxide, Dimethyl
5
Characterizing Idiopathic Normal Pressure Hydrocephalus
The study design and protocol have been approved by the ethics committees for human research at our institute (IRB number: R2019-227). This study followed a prospective and observational design. The study was performed in accordance with the approved guidelines of the Declaration of Helsinki. From November 2020 to February 2022, 133 healthy volunteers aged ≥ 20 years underwent MRI after providing written informed consent explaining the potential for detection of brain disease. Volunteers were recruited from medical staff and students, and their families by open recruitment. Inclusion criteria for this study were those who had no history of brain injury, brain tumor or cerebrovascular disease on previous brain MRI, or those who had never undergone brain MRI and no neurological symptoms including cognitive function. One volunteer aged 84 years old was excluded from this study because of a history of head surgery due to a head injury over 30 years ago. In addition, three volunteers were incidentally found small unruptured intracranial aneurysms with a maximum diameter of < 2 mm on this MRI. They were included in this study, because small unruptured aneurysms might not affect CSF motion.
Patients’ MRI data was used in an opt-out method, after their personal information was anonymized in a linkable manner. Among 44 patients suspected with NPH, 5 patients diagnosed with secondary NPH [29 (link)] that developed after subarachnoid hemorrhage [3 (link)], intracerebral hemorrhage [1 (link)], and severe meningitis [1 (link)], and 3 patients diagnosed with congenital/developmental etiology NPH [30 (link)] were excluded from this study. Finally, 36 patients diagnosed with iNPH who had radiological findings of disproportionately enlarged subarachnoid space hydrocephalus (DESH) [31 (link)], specifically ventricular dilatation, enlarged Sylvian fissure, and narrow sulci at the high convexity, and triad symptoms of gait disturbance, cognitive impairment, and/or urinary incontinence were included in this study, according to the Japanese guidelines for management of iNPH [32 (link)]. Of them, 18 patients (50%) underwent CSF removal in 30–35 ml via a lumbar tap and were evaluated for changes in their symptoms before, one day and two days after the CSF tap test. In addition, 21 patients (86%) underwent CSF shunt surgery and their symptoms improved by ≥ 1 point on the modified Rankin Scale and/or the Japanese iNPH grading scale [32 (link)].
Yamada S., Hiratsuka S., Otani T., Ii S., Wada S., Oshima M., Nozaki K, & Watanabe Y. (2023). Usefulness of intravoxel incoherent motion MRI for visualizing slow cerebrospinal fluid motion. Fluids and Barriers of the CNS, 20, 16.
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Publication 2023
Aneurysm Brain Brain Diseases Brain Injuries Brain Neoplasms Cerebral Hemorrhage Cognition Craniocerebral Trauma Dilatation Disorders, Cognitive Ethics Committees Head Healthy Volunteers Heart Ventricle Homo sapiens Hydrocephalus Intracranial Aneurysm Japanese Lumbar Region Medical Staff Meningitis Neurologic Symptoms Operative Surgical Procedures Patients Shunt, Cerebrospinal Fluid Student Subarachnoid Hemorrhage Subarachnoid Space Triad resin Urinary Incontinence Voluntary Workers X-Rays, Diagnostic

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Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.
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More about "Japanese"

The Japanese people, also known as the Nipponese or Yamato, are an East Asian ethnic group native to the Japanese archipelago.
They have a rich cultural heritage, including unique traditions, cuisine, and art forms.
The Japanese language is a Japonic language that is unrelated to the Sino-Tibetan, Altaic, or any other language family.
In the field of cell culture and biotechnology, the Japanese people have made significant contributions.
Common cell culture media used in Japanese research include DMEM (Dulbeco's Modified Eagle's Medium), RPMI 1640 medium, and supplements such as Penicillin/Streptomycin.
These media provide the necessary nutrients and antibiotics to support the growth and survival of various cell types.
Researchers in Japan have also utilized these cell culture techniques to advance our understanding of Japanese-specific diseases and conditions.
For example, the RPMI-1640 medium has been widely used in studies involving Japanese-derived cell lines and primary cells.
Optimizing research protocols is crucial for Japanese researchers, and tools like PubCompare.ai can help streamline the process.
This AI-driven platform allows researchers to seamlessly locate protocols from literature, pre-prints, and patents, and utilize AI-driven comparisons to identify the best protocols and products for their specific needs.
By leveraging the rich cultural heritage and scientific advancements of the Japanese people, researchers can continue to push the boundaries of knowledge and uncover valuable insights that benefit the global community.