The study was performed in the Jidong community of Tangshan city in Hebei province. The location of the study is illustrated in Fig.
The geographical location of participants in JECS
The geographical location of participants in JECS
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Study flow Diagram
Patients in the two groups received four mesalamine enteric soluble tablets (Sunflower Pharmaceutical Group Jiamusi Luling Pharmaceutical Co., Ltd., State Pharmacopoeia H19980148) orally, thrice daily. The treatment duration was 30d.
Patients in the research group additionally received IMT. ①Donor selection: Adults under 30 years old from a standard fecal bacteria bank, with a healthy lifestyle, good dietary habits, no bad habits such as smoking and drinking, no chronic diseases, no infectious diseases, no chronic diarrhea, constipation, irritable bowel disease, and no history of antibiotic or probiotic and other drug supplements use in the past 3 months were selected. ②Preparation of flora: Fecal bacteria were prepared by the manual method: 200 g of donor stool was collected early in the morning, and 50 g of stool was dissolved in 250 mL of saline, stirred, and filtered through filter sieves of 2-, 1-, 0.5- and 0.25-mm diameter. The supernatant was removed after centrifugation, and the precipitate was resuspended with saline and stored in a −80 °C refrigerator. ③Fecal bacteria transplantation. The frozen bacterial solution was thawed and rewarmed in a 37 °C water bath, 50 g of stool in 250 mL of saline. Transscopic intestinal implantation is adopted. The IMT was performed once a week, with a treatment duration of 30 d. During the treatment, the in-hospital medical staff provided dietary and lifestyle guidance to the patients.
Hospital administration must record the number of staff required at different hours of the day (Fig.
Ranking scores for seniority obtained from the parameters such as years of work experience, certificates, and medical capabilities of the hospital staff (doctors, nurses, and technicians), were recorded on the software’s database. In addition, this information was included in the assignment if the method that prioritized seniority scores was used in scheduling (Fig.
Each person registered in the database must manually enter their preferred number of weekly working hours into the software database. They also needed to select the working time periods (starting and ending hours) they preferred, predefined by the hospital management (Fig.
Finally, hospital management must decide which of the following scheduling methods to apply (Fig.
Data flow diagram of the Work-Life Balance Tool (WLB-Tool) for hospital management
The interface to determine the number of staff for hospital management and requests of staff
Seniority score Priority assignment Method (SPM): It assigned staff by including their scores in the appointments considering their year of employment, seniority, or qualifications. These factors vary from person to person and are required to calculate points for staff and must be saved in the database. A higher score provides priority/advantage in the appointment of staff. This information can only be applied in the Seniority score Priority assignment Method (SPM).
Balanced Fair assignment Method (BFM): This method is an optimization method developed particularly for this study. It is an equitable method for personnel that aims to meet each employee’s demands at the highest rate, focusing on equality and balance in meeting the demands among employees at the same time.
Genetic Algorithm Method (GAM): Genetic algorithms are frequently used optimization procedures based on natural selection and genetics. Therefore, genetic algorithms scan a vast territory of possible problems, and appropriate solutions are obtained quickly. Genetic algorithms were used in the study to meet the requests of all employees at the highest rate.