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Measles virus

Q: Is there a typo in this FAQ?

Yes, there is one typo in the text. The word "Measules" should be "Measles" in the sentence about Measles virus biology, transmission, and treatment.

Measles virus is a highly contagious RNA virus that causes the infectious disease measles.
It is a member of the genus Morbillivirus within the family Paramyxoviridae.
Measles virus primarily infects the respiratory system and can lead to severe complications, including pneumonia, encephalitis, and even death.
Accurate research into measules virus biology, transmission, and treatment is crucial for developing effective prevention and management strategies.
PubCompare.ai's AI-powered tool can enhance Measles virus research by optimizing protocols, locating the best available literature, and identifying optimal solutions to streamline your work.

Most cited protocols related to «Measles virus»

Multiplex RNA-PCR for Respiratory Pathogens

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Publication 2005

Adenoviruses Bacteria Bordetella bronchiseptica Bordetella parapertussis Bordetella pertussis Burkholderia cepacia Chlamydophila pneumoniae Coronavirus 229E, Human Coxsackie Viruses Echovirus Haemophilus influenzae Human parechovirus 1 Klebsiella pneumoniae Legionella pneumophila Measles virus Multiplex Polymerase Chain Reaction Mumps virus Mycoplasma pneumoniae Nucleic Acids Pseudomonas aeruginosa Respiratory Rate Respiratory System Staphylococcus aureus Infection Streptococcus pneumoniae Virus Virus Vaccine, Influenza

Measles Immunity in Healthy Minnesotans

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Publication 2011

Child Childbirth Eligibility Determination Ethics Committees, Research Measles Measles-Mumps-Rubella Vaccine Measles Vaccine Measles virus Parent Response, Immune Strains Young Adult

Cell Culture and Virus Preparation Protocols

Huh7, HeLa and 293T cells were maintained in DMEM (Invitrogen) with 10% FCS and 0.1 mM non-essential amino acids. NIH-3T12 cells were grown in DMEM supplemented with 5% FCS, 100 U penicillin per ml, 100 μg streptomycin per ml and 2 mM L-glutamine. STAT1^−/− fibroblasts (an SV40 large T antigen immortalized human skin fibroblast line) were grown in RPMI (Invitrogen) with 10% FCS. The construction, characterization and generation of viral stocks for the following viruses have been previously described: CVB-GFP (derived from infectious clone pMKS1-GFP)^{24 (link)}, PV-GFP (strain P1M, derived from infectious clone pPVM-2A144-GFP)^{25 (link)}, EAV-GFP (derived from infectious clone pEAV211-GFP2aT)^{26 (link)}, SINV-A-GFP and SINV-G-GFP (derived from infectious clones pS300-GFP and pG100-GFP)^{27 (link)}, ONNV-GFP (derived from infectious clone pONNV.GFP)^{28 (link)}, VEEV-GFP (derived from pTC83-GFP infectious clone)^{4 (link)}, FLUAV-GFP (based on strain PR8)^{29 (link)}, PIV3-GFP (based on strain JS)^{30 (link)}, NDV-GFP (based on strain Hitchner B1)^{31 (link)}, HMPV-GFP^{32 (link)} (based on isolate CAN97-83), RSV-GFP (based on strain A2)^{32 (link)}, MV-GFP (MVvac2-GFP, based on vaccine strain, Edmonston lineage measles virus)^{33 (link)} and BUNV-GFP^{34 (link)} (based on rBUN-del7GFP). VV-GFP was propagated in BSC-40 cells. Viral stocks were prepared by three freeze–thaw cycles, followed by centrifugation at 1,000g to remove cellular debris. VV Western Reserve was obtained from the ATCC, propagated in Vero cells and purified by ultracentrifugation through a 36% sucrose cushion. MHV68 clone WUMS was obtained from the ATCC and propagated in NIH-3T12 cells. The WNV strain was isolated and passaged as described previously^{35 (link)}.

Schoggins J.W., MacDuff D.A., Imanaka N., Gainey M.D., Shrestha B., Eitson J.L., Mar K.B., Richardson R.B., Ratushny A.V., Litvak V., Dabelic R., Manicassamy B., Aitchison J.D., Aderem A., Elliott R.M., García-Sastre A., Racaniello V., Snijder E.J., Yokoyama W.M., Diamond M.S., Virgin H.W, & Rice C.M. (2013). Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature, 505(7485), 691-695.

Publication 2013

Amino Acids, Essential Cells Centrifugation Clone Cells Fibroblasts Freezing Glutamine HEK293 Cells HeLa Cells Homo sapiens Human Metapneumovirus Infection Large T-Antigen Measles virus Penicillins Simian virus 40 Skin STAT1 protein, human Strains Streptomycin Sucrose Ultracentrifugation Vaccines Vero Cells Virus

Estimating Chikungunya Virus Transmission

For immunizing infections such as those due to CHIKV, age-stratified serological surveys can be used to infer the history of circulation in the community [10 (link)]. In such situations, the age of individuals is an indicator of the cumulative time of potential infection risk. Assuming that the risk of infection is age independent, we used a likelihood framework to estimate the annual probability of infection in the population (ie, the proportion of the susceptible population infected per year) for each year between 1952 and 2012. A similar approach has been used to characterize the transmission of measles virus, dengue virus, and other pathogens [10 (link)–12 (link)]. We could not reliably estimate the annual probability of infection before 1952, as there were insufficient individuals in our data set who were alive at the time. Therefore, we assumed a constant probability of infection between 1932 and 1952 and that all individuals were susceptible before 1932. Each individual contributed to estimates of the probability of infection for the years between their birth and the serosurvey. We fit the model in a Bayesian Markov chain Monte Carlo framework, using the RStan package in R [13 ]. Further details of the model can be found in the Supplementary Materials (Text 1).
We compared a model with different annual probabilities of infection (ie, outbreaks lasting 1 year) to models where outbreaks lasted for 2, 3, 4, and 5 years and where the hazard of infection over the entire analyzed period was constant. We defined an outbreak as an event in which at least 1% of the susceptible population was infected over the outbreak period. The total number of outbreaks per model iteration was therefore the total number of periods with an estimated probability of infection of >1%. The deviance information criterion (DIC) was used to compare model fit. DIC differences of <3 as compared to the best model were considered good support for that model, whereas DIC differences of >5 were considered weak support [14 ].

Salje H., Cauchemez S., Alera M.T., Rodriguez-Barraquer I., Thaisomboonsuk B., Srikiatkhachorn A., Lago C.B., Villa D., Klungthong C., Tac-An I.A., Fernandez S., Velasco J.M., Roque VG J.r., Nisalak A., Macareo L.R., Levy J.W., Cummings D, & Yoon I.K. (2015). Reconstruction of 60 Years of Chikungunya Epidemiology in the Philippines Demonstrates Episodic and Focal Transmission. The Journal of Infectious Diseases, 213(4), 604-610.

Publication 2015

Birth Debility Dengue Virus Disease Outbreaks Infection Measles virus Pathogenicity Transmission, Communicable Disease

TCID50 Viral Titration Protocol

We have used TCID50 titration method as a reference for the validation of our rapid titration technique. TCID50 is based on the end-point dilution of the virus at which a cytopathic effect (CPE) is detected in 50% of the cell culture replicates infected by a given amount of virus suspension [2] . The latter was serially diluted in 0.25 ml of DMEM medium supplemented with 6% fetal calf serum (FCS) and antibiotics (culture medium) by serial transfer of 0.027 ml (i.e. ten-fold dilution) in the first row of a 96 well plate. When diluting the virus suspension, each micropipette tip ought to be changed at every dilution to avoid uneven distribution of infectious particles that remain adsorbed on the tip. Subsequently, 0.030 ml of each dilution was distributed vertically, i.e. 8 replicates for each dilution. Permissive cells, i.e. Vero cells, (10,000 cells in 0.2 ml) were seeded in each well, and incubated at 37°C in 5% C0₂ and humid atmosphere. CPE induced by measles virus could be observed under the microscope after 3–4 days, but because CPE located in the well edge could hardly be spotted, the final counting of wells with CPE was done after 10 days. This incubation time can be much shorter for quicker growing viruses (i.e. 1–2 days for VSV). To avoid underestimation of virus titer, the incubation time should be adapted to the virus species and physicochemical conditions used for virus propagation. TCID50 was then calculated using the formula: where “Above 50%” dilution is the last dilution expressed as the denominator of 1 (i.e. 250 for 1/250 dilution) for which ≥50% wells display CPE, (“Above 50%” and “Below 50%” values are fraction of wells with CPE at the last dilution for which ≥50% wells display CPE and fraction of wells with CPE at the next dilution, respectively, and v the virus volume (in ml) from the undiluted sample used to inoculate the wells.

Grigorov B., Rabilloud J., Lawrence P, & Gerlier D. (2011). Rapid Titration of Measles and Other Viruses: Optimization with Determination of Replication Cycle Length. PLoS ONE, 6(9), e24135.

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Publication 2011

Antibiotics Atmosphere Cell Culture Techniques Cells Culture Media Cytopathogenic Effect, Viral Fetal Bovine Serum Genes, Viral Infection Measles virus Microscopy Technique, Dilution Titrimetry Vero Cells Virus

Most recents protocols related to «Measles virus»

Phocine Distemper Virus Outbreak Analysis

Phocine distemper virus is closely related to the canine distemper virus in the Paramyxoviridae family; both pathogens are in the same genus as measles virus [35 (link)]. An outbreak of phocine distemper in 2002 was detected in the North Sea population of harbor seals. First detected on Anhholt Island in Denmark in May, the virus spread into the Netherlands with the first detection on June 16, presumably by the highly mobile gray seals who share haul-outs with harbor seals [36 (link)]. The 2002 outbreak cost an estimated 30,000 harbor seals their lives, making this the largest recorded mass mortality event ever in marine mammals [36 (link)].
Data on seal stranding events were obtained from [37 (link)] and [38 ], who used a public database, waarneming.nl, that contained weekly stranding data collected by seal rescue centers in the region. Stranding events may or may not be lethal, though rescued individuals are removed from the population and brought to local seal rescue centers. We used WebPlotDigitizer software [39 ] to acquire data from published figures from [37 (link)] and [38 ], rounding all digitized values to the nearest integer value. The Dutch outbreak ended by December the same year as indicated by the return of stranding rates to pre-epidemic levels [37 (link)], which resulted in 25 weeks of stranding data. We also obtained annual harbor seal strandings from [38 ] for the three years before the 2002 outbreak (1999–2001) and the three years following the outbreak (2003–2005) to determine the average weekly stranding rates in the absence of the phocine distemper outbreak. We limited our study to these years because the harbor seal population was relatively constant over that period of time [38 ].

Ferguson J.M., González-González A., Kaiser J.A., Winzer S.M., Anast J.M., Ridenhour B., Miura T.A, & Parent C.E. (2023). Hidden variable models reveal the effects of infection from changes in host survival. PLOS Computational Biology, 19(2), e1010910.

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Publication 2023

Distemper Distemper Virus, Canine Distemper Virus, Phocine Epidemics Mammals Marines Measles virus Paramyxoviridae Pathogenicity Phocidae Seal, Gray Seal, Harbor Virus

Profiling Measles Virus RNA Associations with RIG-I in Infected Cells

Briefly, infected HEK-293 cells stably expressing One-STrEP-tagged RIG-I or Cherry protein were lysed with MOPS lysis buffer (20 mM MOPS-KOH pH7.4, 120 mM of KCl, 0.5% Igepal, 2 mM ß-Mercaptoethanol), supplemented with 200 U/mL RNasin (Promega) and Complete Protease Inhibitor Cocktail (Roche). An aliquot of each cell lysate was used to perform total RNA purification using TRI Reagent LS (Sigma). The remaining cell lysate was kept to purify the RIG-I/RNA, or Cherry/RNA complexes by affinity chromatography using StrepTactin Sepharose High Performance beads (GE Healthcare). RNAs that had co-precipitated with either RIG-I or Cherry protein were isolated using TRI Reagent LS. RNA was dissolved in DNase-free and RNase-free ultrapure water. Extracted RNAs were analyzed using the Nanovue (GE Healthcare) and Bioanalyser RNA Nano kit (Agilent). 300 ng of each RNA sample was treated for library preparation using the TruSeq Stranded mRNA Sample Preparation kit (Illumina). Sequencing was performed on the Illumina Hiseq2000 platform to generate single-end 51 bp reads bearing strand specificity [28 (link)]. Three biological experiments were performed.
For the analysis of total and RIG-I/Cherry-specific RNAseq, reads were aligned against Human Genome Reference (GRCh37) with Bowtie2 v2.3.5.1 [48 (link)]. Reads without a positive match against GRCh37, were aligned against the Measles reference genome (NC_001498). Resulting SAM files were analyzed with Samtools v1.13 [49 (link)]. The statistical analyses were performed with SHAMAN (shaman.pasteur.fr) [50 (link)]. The count of reads aligned against Human genome chromosomes and Measles virus were normalized by using the weighted non-null normalization method described in [50 (link)]. Resulting P values were adjusted according to the Benjamini and Hochberg procedure.

Khalfi P., Suspène R., Raymond K.A., Caval V., Caignard G., Berry N., Thiers V., Combredet C., Rufie C., Rigaud S., Ghozlane A., Volant S., Komarova A.V., Tangy F, & Vartanian J.P. (2023). Antagonism of ALAS1 by the Measles Virus V protein contributes to degradation of the mitochondrial network and promotes interferon response. PLOS Pathogens, 19(2), e1011170.

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Publication 2023

2-Mercaptoethanol Biopharmaceuticals Buffers Cells Chromatography, Affinity Chromosomes Chromosomes, Human DDX58 protein, human Deoxyribonucleases DNA Library Endoribonucleases Genome Genome, Human HEK293 Cells Measles Measles virus morpholinopropane sulfonic acid Promega Protease Inhibitors Proteins Prunus cerasus RNA, immune RNA, Messenger Sepharose Shamans

Evaluating Recall Responses to Tetanus Toxoid in HIV-Infected Individuals

HIV-infected persons on antiretroviral therapy (ART) were recruited from the Erlangen HIV cohort at the Universitätsklinikum in Erlangen. HIV-uninfected persons were recruited through the Institute of Clinical and Molecular Virology of the Universitätsklinikum in Erlangen. For the comparison of the recall TT responses between HIV-infected and HIV-uninfected groups, individuals with self-reported prior vaccination were recruited. These were 14 HIV-uninfected persons with a median age of 49 years (interquartile range (IQR) 44–54) and 33 HIV-infected persons with a median age of 51 years (IQR 40–54) and a median CD4 T cell count of 647 cells/mm³ (IQR 538–794). To assess the effect of anti-PD-1 and anti-PD-L1 antibodies on the recall IFNγ responses of HIV-infected persons on ART, lymphocytes of 30 HIV-infected TT-seropositive and 29 HIV-infected measles virus (MV)-seropositive subjects were probed. Detailed characteristics of the 30 TT- and 29 MV-seropositive participants are presented in Table 1.
The study was approved by the ethics committees of the Universitätsklinikum Erlangen (numbers 235-18B and 250-15B) and carried out in compliance with institutional guidelines. All participants gave written informed consent.

Fischhaber N., Schmiedeberg M., Kübel S., Harrer E.G., Harrer T, & Nganou-Makamdop K. (2023). Ex Vivo Blockade of the PD-1 Pathway Improves Recall IFNγ Responses of HIV-Infected Persons on Antiretroviral Therapy. Vaccines, 11(2), 211.

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Publication 2023

CD4+ Cell Counts CD274 protein, human Cells Ethics Committees HIV Antibodies HIV Seropositivity Interferon Type II Lymphocyte Measles virus Mental Recall Therapeutics Vaccination

Recall IFNγ Responses to Tetanus Toxoid in HIV

For a comparison of the recall IFNγ responses to TT between HIV-infected and HIV-uninfected persons, cryopreserved PBMCs were thawed, washed in R10 medium and rested for 6 h at 37 °C. Following the seeding of 1 × 10⁶ cells per well, PBMCs in R10 were either left untreated or stimulated with TT protein (Tetanol, GSK—0.5 I.E) and incubated at 37 °C in 5% CO₂ for 3 days. To assess the effect of anti-PD-1 and anti-PD-L1 on recall IFNγ responses, cryopreserved PBMCs were thawed, washed in R10 medium and rested overnight at 37 °C. Cells were washed, seeded in 96-well round bottom plates at 0.9 × 10⁶ cells per well in R10 medium and incubated for 6 h with 20 µg/mL or 40 µg/mL anti-PD-1 (Nivolumab), anti-PD-L1 (Durvalumab), or their respective IgG4 and IgG1 isotype controls (BioXCell). Next, TT protein (Tetanol, GSK—0.5 I.E) or an MV 20-mer overlapping peptide pool corresponding to the measles virus hemagglutinin and fusion proteins (EMC, 10 µg/mL) was added per well. As a positive control, PBMCs were stimulated with Staphylococcal enterotoxin B (SEB, Sigma, 0.25 µg/mL final concentration). As negative controls, PBMCs were either unstimulated (TT control) or supplemented with DMSO (MV peptide pool control). Following the addition of all stimuli, cells were incubated at 37 °C in 5% CO₂ for 3 days. All cell culture supernatants were collected after 3 days of stimulation for the measurement of IFNγ concentrations using the human IFNγ Duoset (R&D) as per the manufacturer’s recommendation. Measurement of IFNγ concentrations was performed in duplicate and the average of the duplicates was reported.

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Publication 2023

CD274 protein, human Cell Culture Techniques Cells durvalumab enterotoxin B, staphylococcal Hemagglutinin Homo sapiens IgG1 IgG4 Immunoglobulin Isotypes Interferon Type II Measles virus Mental Recall Nivolumab Peptides Proteins Sulfoxide, Dimethyl

Titration of dCoV, Measles, and Rubella Vaccines

The dCoV vaccine strain was titrated using a standard plaque assay. Briefly, a Vero cell monolayer was prepared in 6-well plates one day prior to virus titration. A ten-fold serial dilution of the samples were prepared in Dulbecco’s Minimum Essential Medium (DMEM) containing 2% fetal bovine serum (FBS). The cell monolayer was washed once with DMEM and infected with serially diluted samples. After 1 h of incubation at 37 °C, 4.0 mL of overlay medium (1.25% carboxymethyl cellulose in DMEM containing 2% FBS) was added on the top of inoculums and further incubated at 37 °C undisturbed. After 3 days, the cells were washed with phosphate-buffered saline (PBS) and the plaques were visualized via negative staining with 0.3% crystal violet in 5% formalin. Excess stain was washed off using water. Distinctly countable plaques (between 20 to 120 plaques per well) were counted and the virus titer was calculated per the method described by Darling et al., 1998. Virus titers were expressed as Log₁₀ plaque-forming units per 0.5 mL (Log₁₀ PFU/0.5 mL) or per dose as applicable.
Measles and rubella viruses were titrated using the standard CCID₅₀ assay. Measles virus was titrated using Vero cells plated on the day of test while rubella virus was titrated in RK-13 cells plated one day prior to test in 96-well plates. After infection with 10-fold serially diluted samples, the 96-well plates were incubated and observed microscopically on day 7 through day 10 post-infection for the cytopathic effect (CPE) indicating the presence of virus. The 50% end point was calculated using the Spearman and Karber method and the titers were represented as Log₁₀ CCID₅₀/dose.

Mehla R., Kokate P., Bhosale S.R., Vaidya V., Narayanan S., Shandil R.K., Singh M., Rudramurthy G.R., Naveenkumar C.N., Bharathkumar K., Coleman R., Mueller S., Dhere R.M, & Yeolekar L.R. (2023). A Live Attenuated COVID-19 Candidate Vaccine for Children: Protection against SARS-CoV-2 Challenge in Hamsters. Vaccines, 11(2), 255.

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Publication 2023

Biological Assay Carboxymethylcellulose Cells Cytopathogenic Effect, Viral Dental Plaque Fetal Bovine Serum Formalin Infection Measles Measles virus Phosphates Rubella virus Saline Solution Senile Plaques Stains Strains Technique, Dilution Titrimetry Vaccines Vero Cells Violet, Gentian Virus

Top products related to «Measles virus»

Fetal bovine serum (fbs) by Thermo Fisher Scientific

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Fetal Bovine Serum (FBS) is a cell culture supplement derived from the blood of bovine fetuses. FBS provides a source of proteins, growth factors, and other components that support the growth and maintenance of various cell types in in vitro cell culture applications.

Qiaamp viral rna mini kit by Qiagen

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The QIAamp Viral RNA Mini Kit is a laboratory equipment designed for the extraction and purification of viral RNA from various sample types. It utilizes a silica-based membrane technology to efficiently capture and isolate viral RNA, which can then be used for downstream applications such as RT-PCR analysis.

Enzygnost anti measles virus igm by Siemens

Sourced in Germany

Enzygnost Anti-Measles-Virus/IgM is a lab equipment product designed for the detection of measles virus-specific IgM antibodies in human serum or plasma samples. It is an enzyme immunoassay that can be used as an aid in the diagnosis of measles infection.

Enzygnost anti measles virus igg by Siemens

Sourced in Germany

The Enzygnost® Anti-Measles Virus/IgG is a laboratory diagnostic test used to detect the presence of antibodies against the measles virus in human serum or plasma samples. The test utilizes an enzyme immunoassay (EIA) technique to measure the level of measles-specific IgG antibodies.

Dmem f12 by Thermo Fisher Scientific

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DMEM/F12 is a cell culture medium developed by Thermo Fisher Scientific. It is a balanced salt solution that provides nutrients and growth factors essential for the cultivation of a variety of cell types, including adherent and suspension cells. The medium is formulated to support the proliferation and maintenance of cells in vitro.

Dulbecco modified eagle medium (dmem) by Thermo Fisher Scientific

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DMEM (Dulbecco's Modified Eagle's Medium) is a cell culture medium formulated to support the growth and maintenance of a variety of cell types, including mammalian cells. It provides essential nutrients, amino acids, vitamins, and other components necessary for cell proliferation and survival in an in vitro environment.

Luciferase assay system by Promega

Sourced in United States, Germany, United Kingdom, Australia, Switzerland, Japan, China, France, Sweden, Italy, Spain, Austria, Finland

The Luciferase Assay System is a laboratory tool designed to measure the activity of the luciferase enzyme. Luciferase is an enzyme that catalyzes a bioluminescent reaction, producing light. The Luciferase Assay System provides the necessary reagents to quantify the level of luciferase activity in samples, enabling researchers to study biological processes and gene expression.

Ix71 fluorescent microscope by Media Cybernetics

The IX71 Fluorescent microscope is a compact and versatile imaging system designed for fluorescence microscopy. It features a high-resolution optical system, advanced illumination capabilities, and a user-friendly interface. The IX71 is capable of capturing detailed images of fluorescently labeled samples, making it a valuable tool for a wide range of applications in life science research and other fields.

Alexa fluor 594 donkey anti mouse igg h l by Thermo Fisher Scientific

Sourced in United States

Alexa Fluor 594 donkey anti-mouse IgG (H+L) is a secondary antibody conjugated with the Alexa Fluor 594 fluorescent dye. It is designed to detect and visualize mouse primary antibodies in various immunoassays and imaging applications.

Clsm780 confocal laser scanning microscope by Zeiss

The CLSM780 is a confocal laser scanning microscope manufactured by Zeiss. It utilizes a laser-based optical scanning system to acquire high-resolution, three-dimensional images of samples. The microscope is designed to provide detailed information about the structure and composition of biological and materials science specimens.

What are the different types or variations of the Measles virus?

The Measles virus belongs to the genus Morbillivirus within the family Paramyxoviridae. There are multiple genotypes (genetic variations) of the Measles virus that have been identified, including A, B, C, D, E, F, G, H, and others. These genotypes can have slight differences in their genetic makeup, which can impact their behavior and characteristics. However, the core biological properties of the virus remain largely consistent across the different genotypes.

How can the Measles virus be transmitted?

The Measles virus is highly contagious and is primarily transmitted through direct contact with respiratory droplets or airborne particles expelled when an infected person coughs or sneezes. The virus can also be transmitted through contact with contaminated surfaces or objects. In some cases, the virus can remain airborne for up to two hours after an infected person has left an area, posing a risk of transmission to others.

What are some of the common complications associated with Measles virus infection?

Measles virus infection can lead to several severe complications, including pneumonia, encephalitis (brain inflammation), and even death. Pneumonia is one of the most common complications, and it can be particularly dangerous for young children, the elderly, and those with weakened immune systems. Encephalitis, while less common, can result in brain damage and can be life-threatening. Other potential complications include ear infections, diarrhea, and temporary suppression of the immune system.

How can PubCompare.ai assist with Measles virus research?

PubCompare.ai's AI-powered tool can enhance Measles virus research in several ways. First, it allows researchers to screen protocol literature more efficiently by leveraging AI to pinpoint critical insights. The platform's AI-driven analysis can highlight key differences in protocol effectiveness, enabling researchers to choose the best option for reproducibility and accuracy. This can be particularly useful when trying to identify the most effective protocols related to Measles virus for specific research goals. Additionally, PubCompare.ai can help researchers locate the best available protocols from literature, pre-prints, and patents, streamlining the research process and helping to ensure the use of optimal solutions.

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More about "Measles virus"

Measles is a highly contagious viral illness caused by the measles virus, a member of the Morbillivirus genus within the Paramyxoviridae family.
This RNA virus primarily infects the respiratory system and can lead to severe complications, including pneumonia, encephalitis, and even death.
Accurate research into the biology, transmission, and treatment of the measles virus is crucial for developing effective prevention and management strategies.
PubCompare.ai's AI-powered tool can enhance measles virus research by optimizing protocols, locating the best available literature, and identifying optimal solutions to streamline your work.
The measles virus can be studied using various techniques and reagents, such as the QIAamp Viral RNA Mini Kit for RNA extraction, the Enzygnost Anti-Measles-Virus/IgM and Enzygnost® Anti-Measles Virus/IgG assays for serological detection, and cell culture models in DMEM/F12 or DMEM media.
Fluorescence-based methods, like the Luciferase Assay System and fluorescent microscopy using the IX71 microscope and Alexa Fluor 594 donkey anti-mouse IgG (H+L) antibody, can provide insights into viral entry, replication, and cellular responses.
By leveraging PubCompare.ai's intelligent comparisons and AI-driven protocol optimization, researchers can streamline their measles virus studies, locate the best available protocols from literature, pre-prints, and patents, and identify the optimal solutions to advance their work.
This can lead to more accurate and efficient measles virus research, ultimately contributing to the development of effective prevention and treatment strategies.