Male apolipoprotein B100-only, low density lipoprotein receptor (LDLr) deficient (LDLr-/-Apob100/100) mice were used in this study. These mice were chosen based on previous reports documenting their “human-like” lipoprotein profile,20 (link) atherosclerosis susceptibility,20 (link) and responsiveness to dietary fatty acids.21 (link) All mice were on a mixed background (∼75% C57BL/6 and ∼25% 129Sv/Jae). At 6 weeks of age, the mice were switched from a diet of rodent chow to one of two synthetic diets containing 12% of energy as saturated fatty acid (SFA)-enriched fat (palm oil) or monounsaturated fatty acid (MUFA)-enriched fat (oleinate-enriched safflower oil) with 0.1% (w/w) cholesterol added. Please refer to Supplemental Table 1 (online) for complete analysis of dietary fatty acid composition. In conjunction with diet, mice were injected biweekly with either saline, 25 mg/kg of a non-targeting ASO (control ASO; 5 ′- TCCCATTTCAGGAGACCTGG -3′), or 25 mg/kg of an ASO targeting the knockdown of SCD1 (SCD1 ASO; 5′-GCTCTAATCACCTCAGAACT -3′). These phosphorothioate modified ASO compounds were generously provided by ISIS Pharmaceuticals, Inc. (Carlsbad, CA). Body weight was measured weekly, and food intake was measured at four weeks and eight weeks of diet/ASO treatment. All experimental animals were sacrificed after 20 weeks of parallel dietary and ASO treatment. All mice were maintained in a pathogen-free animal facility, and experimental protocols were approved by the institutional animal care and use committee at the Wake Forest University School of Medicine.
Safflower oil
Safflower oil is a versatile vegetable oil extracted from the seeds of the safflower plant.
It is commonly used in cooking, skincare, and as a dietary supplement.
Safflower oil is rich in linoleic acid, an essential omega-6 fatty acid, and has a high smoke point, making it suitable for high-temperature cooking.
It is also known for its potential health benefits, such as supporting cardiovascular health and skin moisturization.
Researchers can leverage PubCompare.ai's AI-powered platform to optimize their safflower oil research, locating protocols from literature, preprints, and patents, and leveraging AI-driven comparisons to identify the best protocols and products.
This can help streamline the research process and make more informed decisions.
Experence the power of AI-driven research today with PubCompare.ai.
It is commonly used in cooking, skincare, and as a dietary supplement.
Safflower oil is rich in linoleic acid, an essential omega-6 fatty acid, and has a high smoke point, making it suitable for high-temperature cooking.
It is also known for its potential health benefits, such as supporting cardiovascular health and skin moisturization.
Researchers can leverage PubCompare.ai's AI-powered platform to optimize their safflower oil research, locating protocols from literature, preprints, and patents, and leveraging AI-driven comparisons to identify the best protocols and products.
This can help streamline the research process and make more informed decisions.
Experence the power of AI-driven research today with PubCompare.ai.
Most cited protocols related to «Safflower oil»
Animals
Animals, Laboratory
Apolipoprotein B-100
Arteriosclerosis
Body Weight
Cholesterol
Diet
Eating
Fatty Acids
Fatty Acids, Monounsaturated
Forests
Homo sapiens
Institutional Animal Care and Use Committees
LDLR protein, human
Lipoproteins
Low Density Lipoprotein Receptor
Males
Mice, House
Palm Oil
pathogenesis
Pharmaceutical Preparations
Rodent
Safflower oil
Saline Solution
Saturated Fatty Acid
Susceptibility, Disease
Synthetic Diet
Therapy, Diet
Diploid Cell
Estradiol
Estrous Cycle
Human Body
Hypersensitivity
Inflammation
Injuries
Muscles, Masseter
Muscle Tissue
Ovariectomy
Pharmaceutical Adjuvants
Rattus norvegicus
Safflower oil
Saline Solution
All experiments were approved by the Institutional Animal Care and Use Committee at Michigan State University in accordance with the National Institutes of Health guidelines for animal use. Female 7 wk old lupus-prone NZBWF1 and control C57Bl/6 mice were obtained from Jackson Laboratories (Bar Harbor, ME), randomized into treatment groups, and allowed to acclimate for 2 wk prior to cSiO2 exposure. Upon arrival and throughout the study, mice were fed semi-purified American Institute of Nutrition (AIN)-93G diet containing high oleic safflower oil [34 (link)]. Mice were housed 4 per cage with free access to food and water and maintained at constant temperature and humidity (21°C–24°C and 40–55%, respectively) under a 12-h light/dark cycle.
Full text: Click here
Animals
Diet
Females
Food
Humidity
Institutional Animal Care and Use Committees
Lupus Vulgaris
Mice, House
Mice, Inbred C57BL
Safflower oil
Anesthesia
Animals
BLOOD
Brain
Capsule
Cranium
Enrofloxacin
Estradiol
estradiol 3-benzoate
Females
Hormones
Injections, Intraperitoneal
Institutional Animal Care and Use Committees
Insulin Isophane
Isoflurane
Ketamine
Ketoprofen
Light
Metestrus
Microwaves
Operative Surgical Procedures
Plasma
Rats, Laboratory
Rats, Sprague-Dawley
Rattus norvegicus
Safflower oil
Silastic
Solon
Sterility, Reproductive
Steroids
Sulfoxide, Dimethyl
Tissues
Treatment Protocols
Woman
Xylazine
The use of M. fusata by our consortium of investigators has been previously described 26 –31 (link). In brief, animals were socially housed (4–9 females and 1–2 males per group) within indoor/outdoor enclosures at the Oregon National Primate Research Center (ONPRC) and in accordance with the institutional animal care and use committees (IACUC) at both Baylor College of Medicine and ONPRC. Animals were on an isocaloric diet and were either fed a control diet of standard chow (Monkey Diet no. 5000; Purina Mills Co., St. Louis, MO) consisting of 13% fat from soya bean oil or high-fat diet (TAD Primate Diet 5LOP, Test Diet, Richmond, IN) consisting of 36% fat from lard, butter, animal fat, and safflower oil that is additionally supplemented with calorically dense treats (consisting of Glaxo powder/TAD pellets, peanut butter, honey, banana, and cornstarch). Animals bred naturally, and offspring (both male and female) were maintained on a similar diet as their mothers until weaning (6–7 months) when the offspring either became part of the control cohort (maintaining the same diet as their mothers’) or the crossover cohort (switching the diet from their mothers’). Control or high fat diet cohorts were designated randomly. Animals were housed socially and based on diet. More specifically, since juveniles exposed to CTD/CTD or HFD/HFD did not change diets, these animals maintained housing with others on the CTD or HFD, respectively; however, CTD/HFD and HFD/CTD juveniles switched housing upon weaning to accommodate their crossover diet. This resulted in the exposure of all juvenile cohorts to the intestinal microbiome based on CTD or HFD. Specifically, for the CTD/HFD juvenile cohorts, these animals were housed with CTD animals until weaning, when they were then cohoused with HFD animals. Conversely, for HFD/CTD juvenile cohorts, these animals were housed with HFD animals until weaning when they were housed with CTD animals. Additionally, animals utilized in this study were not treated with antibiotics and had no gross evidence of malabsoprtion or chronic diarrhea. Therefore, dysbiosis detected in the microbiome are solely due to differences in diet. At one year of age, juveniles were sacrificed by anesthetizing with sodium pentobarbital prior to exsanguination.
Animals
Animals, Domestic
Antibiotics, Antitubercular
Arachis hypogaea
Banana
Butter
Cornstarch
Diarrhea
Diet
Diet, High-Fat
Dysbiosis
Exsanguination
Females
Honey
Institutional Animal Care and Use Committees
Intestinal Microbiome
lard
Males
Men
Microbiome
Monkeys
Mothers
Pellets, Drug
Pentobarbital Sodium
Pharmaceutical Preparations
Powder
Primates
Safflower oil
Soybean oil
Therapy, Diet
Most recents protocols related to «Safflower oil»
Example 12
The composite plant-MCT flour of any of Examples 1-11 is modified by including one or more supplemental oils in addition to and/or that replace a portion of the MCT oil, including one or more of avocado oil, Brazil nut oil, canola oil, corn oil, cottonseed oil, flaxseed oil, grape see oil, hemp seed oil, olive oil, palm oil, peanut oil, rice bran oil, safflower oil (e.g., high oleic), sesame oil, soybean oil, walnut oil, hazelnut oil, sunflower oil, or butterfat.
Full text: Click here
Brazil Nuts
Canola Oil
Corn oil
Flour
Food
Grapes
Hazelnuts
hempseed oil
Juglans
Linseed oil
MCTS1 protein, human
Oil, Cottonseed
Oil, Olive
Oil, Sunflower
Palm Oil
Peanut Oil
Persea americana
Plants
Rice Bran Oil
Safflower oil
Sesame Oil
SLC16A11 protein, human
Soybean oil
Hair dye, botanic brand
hair bleaching powder, and volume oxidation cream were provided by
a cosmetics firm. Natural dark brown hair samples were taken from
Imhair (Italy). A base shampoo formula was prepared for shampoo application
to the hair samples (Table 1 ). In addition to the given formulation, an oxidizing agent
concentration was used at a maximum of 0.05% (w/w) for wearing out
the hair. Also, the oxidizing agent concentration was utilized at
a maximum of 1% (w/w) for dyed hair.
The herbal oils used (safflower seed oil, grape seed
oil, and rosehip
oil) were bought from the market. The major fatty acid of safflower
seed oil was linoleic acid, which accounted for 70% in the oil. The
rosehip seed oil contained polyunsaturated fatty acids, linoleic acid
(54%), linolenic acid (19%), phytosterols, and β-sitosterol
(82%). The grape seed oils contained stearic acid (6%), palmitic acid
(9%), oleic acid (15%), and linoleic acid (70%).
hair bleaching powder, and volume oxidation cream were provided by
a cosmetics firm. Natural dark brown hair samples were taken from
Imhair (Italy). A base shampoo formula was prepared for shampoo application
to the hair samples (
concentration was used at a maximum of 0.05% (w/w) for wearing out
the hair. Also, the oxidizing agent concentration was utilized at
a maximum of 1% (w/w) for dyed hair.
The herbal oils used (safflower seed oil, grape seed
oil, and rosehip
oil) were bought from the market. The major fatty acid of safflower
seed oil was linoleic acid, which accounted for 70% in the oil. The
rosehip seed oil contained polyunsaturated fatty acids, linoleic acid
(54%), linolenic acid (19%), phytosterols, and β-sitosterol
(82%). The grape seed oils contained stearic acid (6%), palmitic acid
(9%), oleic acid (15%), and linoleic acid (70%).
Full text: Click here
Fatty Acids
Grapes
Hair
Hair Dyes
Linoleic Acid
Linolenic Acid
Oils
Oleic Acid
Oxidants
Palmitic Acid
Phytosterols
Plants
Polyunsaturated Fatty Acids
Powder
Safflower oil
sitosterol
stearic acid
One sample
from each of the different types of hair samples was taken and set
aside as the reference hair sample. One of them was set aside for
shampoo application only. Safflower seed oil was applied to one, rosehip
oil to one, and grapeseed oil to one of the remaining three hair samples
from each hair type. Oils (0.5 mL) were applied to the hair with the
help of a pipette. The oils were left on the hair for 12 h. While
determining the optimum ratio for the oil applied to the hair, trials
were carried out in the range of 0.1–1.0 mL. As a result of
the tests and analyses such as color, stretching, elongation, morphological
appearance, etc., no change was observed in the properties of the
hair samples after a certain value. For this reason, all test and
analysis results were compared in detail, and the optimum amount to
be applied to the hair was determined as 0.5 mL. This rate corresponded
to a rate of 1.5% (v/w) over the determined amount of hair. In practice,
the minimum time for all applications to the hair was 12 h. In addition,
because of the preliminary trials performed between 6 and 24 h, there
was no significant change in the analysis and test results after 12
h. Therefore, the optimum time was determined as 12 h. After 12 h,
the hair was washed with a base shampoo and oiled again. This washing,
drying, and oiling process was repeated 10 times. After the 10th lubrication,
the hair was washed again with a base shampoo, dried, and ready for
tests. Some images taken while applying oil to hair samples are given
inFigure 4 . In this
experiment, safflower seed oil, grape seed oil, and rosehip oil were
used comparatively.
from each of the different types of hair samples was taken and set
aside as the reference hair sample. One of them was set aside for
shampoo application only. Safflower seed oil was applied to one, rosehip
oil to one, and grapeseed oil to one of the remaining three hair samples
from each hair type. Oils (0.5 mL) were applied to the hair with the
help of a pipette. The oils were left on the hair for 12 h. While
determining the optimum ratio for the oil applied to the hair, trials
were carried out in the range of 0.1–1.0 mL. As a result of
the tests and analyses such as color, stretching, elongation, morphological
appearance, etc., no change was observed in the properties of the
hair samples after a certain value. For this reason, all test and
analysis results were compared in detail, and the optimum amount to
be applied to the hair was determined as 0.5 mL. This rate corresponded
to a rate of 1.5% (v/w) over the determined amount of hair. In practice,
the minimum time for all applications to the hair was 12 h. In addition,
because of the preliminary trials performed between 6 and 24 h, there
was no significant change in the analysis and test results after 12
h. Therefore, the optimum time was determined as 12 h. After 12 h,
the hair was washed with a base shampoo and oiled again. This washing,
drying, and oiling process was repeated 10 times. After the 10th lubrication,
the hair was washed again with a base shampoo, dried, and ready for
tests. Some images taken while applying oil to hair samples are given
in
experiment, safflower seed oil, grape seed oil, and rosehip oil were
used comparatively.
Full text: Click here
Factor V
Grapes
Hair
Lubrication
Rosehips
Safflower oil
Four defined diet formulations were prepared as described in Supplementary Table 3 Table 1 Supplementary Table 4
Full text: Click here
Acids, Omega-6 Fatty
Corn oil
DHA-10
Diet
Dietary Formulations
Fatty Acids
Food
Homo sapiens
Microalgae
Rodent
Safflower oil
WT, Ube3am–/p+ (maternal transmission), and Ube3am+/p– (paternal transmission) mice (6-8 weeks old) were pair-fed for 8-12 weeks (before DRG dissection or behavioral experiments) with a: A) standard diet (sd; #7012 ENVIGO; UTHSC animal facility diet; (https://insights.envigo.com/hubfs/resources/data-sheets/7012-datasheet-0915.pdf ); B) Safflower oil-supplemented diet (enriched in LA, Dyets # 112245). Modified AIN-93G purified rodent diet with 59% fat derived calories from safflower oil (kcal/kg): Casein (716), L-Cystine (12), Maltose Dextrin (502), Cornstarch (818.76), Safflower Oil (2430), Soybean Oil (630), Mineral Mix (# 210025; 30.8), and Vitamin Mix (#310025; 38.7); C) High-fat diet (anhydrous milk fat supplemented, Dyets # 105012). Modified AIN-93G Purified Rodent Diet with 59% Fat Derived Calories from Anhydrous Milk Fat (kcal/kg): Casein (716), L-Cystine (12), Maltose Dextrin (502), Cornstarch (818.76), Anhydrous Milk Fat (2430), Soybean Oil (630), Mineral Mix (# 210025; 30.8), and Vitamin Mix (#310025; 38.7).
Full text: Click here
Animals
Caseins
Cornstarch
Cystine
Dextrin
Diet, High-Fat
Dietary Fats
Dissection
Maltose
Mice, House
Milk, Cow's
Minerals
Rodent
Safflower oil
Soybean oil
Therapy, Diet
Transmission, Communicable Disease
Vertical Infection Transmission
Vitamins
Top products related to «Safflower oil»
Sourced in United States, Germany
Safflower seed oil is a plant-derived oil extracted from the seeds of the safflower plant. It is a clear, odorless, and light-colored oil with a high content of polyunsaturated fatty acids, primarily linoleic acid.
Sourced in United States, Germany, Sao Tome and Principe, United Kingdom, Switzerland, Macao, China, Australia, Canada, Belgium, Japan, Spain, France, Italy, New Zealand, Denmark
Tamoxifen is a drug used in the treatment of certain types of cancer, primarily breast cancer. It is a selective estrogen receptor modulator (SERM) that can act as both an agonist and antagonist of the estrogen receptor. Tamoxifen is used to treat and prevent breast cancer in both men and women.
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DMSO is a versatile organic solvent commonly used in laboratory settings. It has a high boiling point, low viscosity, and the ability to dissolve a wide range of polar and non-polar compounds. DMSO's core function is as a solvent, allowing for the effective dissolution and handling of various chemical substances during research and experimentation.
Sourced in United States, Australia
AIN93VX-vitamin mix is a laboratory product formulated to provide a complete set of vitamins for animal diets. It contains a standardized blend of essential vitamins necessary for animal health and development. The product is intended for use in the formulation of specialized animal feeds or research diets.
Sourced in United States
Na-HEPES is a commonly used buffer solution for maintaining pH in various biological and biochemical applications. It is a sodium salt of the N-2-Hydroxyethylpiperazine-N'-2-ethanesulfonic acid (HEPES) buffer. Na-HEPES is designed to maintain a stable pH around 7.5 in aqueous solutions.
Sourced in United States, Germany, Italy, China, France, Japan, Australia, Mexico, Macao, New Zealand, Canada, Chile, Malaysia, Singapore, Sao Tome and Principe, Poland, Spain, Norway, United Kingdom, Brazil, India
α-tocopherol is a chemical compound that functions as a natural antioxidant. It is a type of vitamin E found in various plant oils and other food sources.
Sourced in United States, China, Germany, Japan, Canada, United Kingdom, France, Italy, Morocco, Sweden
Male Sprague-Dawley rats are a widely used laboratory animal model. They are characterized by their large size, docile temperament, and well-established physiological and behavioral characteristics. These rats are commonly used in a variety of research applications.
Sourced in Panama
Tocopherol-stripped safflower oil is a laboratory product that has had its tocopherol (vitamin E) content removed. It is a clear, odorless oil derived from the seeds of the safflower plant.
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SigmaStat 3.5 is a statistical analysis software package developed by Merck Group. It is designed to perform a variety of statistical tests and analyses on data. The software provides tools for data manipulation, hypothesis testing, and visualization. SigmaStat 3.5 is intended for use in scientific and research applications.
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MgSO4 is a chemical compound commonly known as magnesium sulfate. It is a white, crystalline salt that is soluble in water. MgSO4 is a versatile laboratory reagent used in various applications, including as a desiccant, electrolyte, and precipitating agent.
More about "Safflower oil"
Safflower, also known as Carthamus tinctorius, is a versatile and widely used plant that has been cultivated for centuries.
The seeds of the safflower plant are the source of safflower oil, a valuable vegetable oil that is prized for its numerous applications and potential health benefits.
Safflower oil is rich in linoleic acid, an essential omega-6 fatty acid, and has a high smoke point, making it suitable for high-temperature cooking.
It is commonly used in culinary applications, such as frying, baking, and as a salad dressing or cooking oil.
Safflower oil is also used in skincare products due to its moisturizing and nourishing properties.
In addition to its culinary and cosmetic uses, safflower oil has been studied for its potential health benefits.
Research suggests that safflower oil may support cardiovascular health by helping to maintain healthy cholesterol levels and blood pressure.
It has also been investigated for its potential role in skin moisturization and maintaining healthy skin.
Researchers can leverage the power of AI-driven platforms like PubCompare.ai to optimize their safflower oil research.
These tools can help researchers locate protocols from literature, preprints, and patents, and compare them to identify the most effective and efficient methods.
By streamlining the research process and making more informed decisions, researchers can accelerate their safflower oil studies and unlock new insights.
Experence the power of AI-driven research today with PubCompare.ai and explore the exciting possibilities of safflower oil and its diverse applications.
The seeds of the safflower plant are the source of safflower oil, a valuable vegetable oil that is prized for its numerous applications and potential health benefits.
Safflower oil is rich in linoleic acid, an essential omega-6 fatty acid, and has a high smoke point, making it suitable for high-temperature cooking.
It is commonly used in culinary applications, such as frying, baking, and as a salad dressing or cooking oil.
Safflower oil is also used in skincare products due to its moisturizing and nourishing properties.
In addition to its culinary and cosmetic uses, safflower oil has been studied for its potential health benefits.
Research suggests that safflower oil may support cardiovascular health by helping to maintain healthy cholesterol levels and blood pressure.
It has also been investigated for its potential role in skin moisturization and maintaining healthy skin.
Researchers can leverage the power of AI-driven platforms like PubCompare.ai to optimize their safflower oil research.
These tools can help researchers locate protocols from literature, preprints, and patents, and compare them to identify the most effective and efficient methods.
By streamlining the research process and making more informed decisions, researchers can accelerate their safflower oil studies and unlock new insights.
Experence the power of AI-driven research today with PubCompare.ai and explore the exciting possibilities of safflower oil and its diverse applications.