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Tidal Volume

Tidal volume refers to the volume of air that moves in and out of the lungs with each normal breath.
It is an important parameter in respiratory physiology and critical for assessing lung function.
Accurate measurement and optimization of tidal volume is crucial in various medical and research applications, such as mechanical ventilation, exercise physiology, and the study of respiratory diseases.
PubCompare.ai, an AI-driven platform, can help streamline your tidal volume research by easily locating and comparing protocols from scientific literature, preprints, and patents.
Its advanced AI-driven comparisons identify the best protocols and products, enhancing reproducibility and accuracy.
Experience the power of AI-assisted tidal volume optimization with PubCompar.ai.

Most cited protocols related to «Tidal Volume»

1
Evaluating Activity Monitors in COPD Patients
Each patient wore 6 activity monitors simultaneously which were selected as a result of a systematic review of the literature. These were two uniaxial activity monitors [Kenz Lifecorder (Kenz), Actiwatch (Actiwatch)], three triaxial activity monitors [RT3, Actigraph GT3X (Actigraph), DynaPort MiniMod (MiniMod)] and one multisensor activity monitor combining a triaxial accelerometer with different sensors [SenseWear Armband (SenseWear)]. More details about software, type, body location and outputs of these monitors can be found in Table 1.
Patients also wore a portable metabolic system (Jaeger Oxycon Mobile), an oxygen saturation finger probe and a Polar T31 (Polar) coded transmitter belt for heart rate monitoring. The portable metabolic system was attached to the upper chest with a harness and due to its low weight (950 g), caused minimal discomfort. A face mask with a dead space of <30 mL (Hans Rudolph Inc, Kansas City MO/USA) was used. Location of attachment for the Oxycon Mobile together with the six activity monitors is shown in Figure 1. A two-point gas calibration was completed prior to each test. Oxygen consumption (VO2), carbon dioxide production (VCO2), heart rate, respiratory rate and tidal volume were measured continuously. Breath-by-breath measurements were averaged over one-minute intervals. After the experiment, stored data were downloaded from the portable metabolic device to a personal computer. VO2 values were divided by participants’ body weight and converted to Metabolic Equivalents of Task (METs) [24] . Energy expenditure estimates from the portable metabolic system (METs) were used as a criterion measure for energy expenditure and were compared with the following activity monitor outputs: Kenz - arbitrary units (AU); Actiwatch - activity counts (AC); Actigraph and RT3 - vector magnitude units (VMU); MiniMod and SenseWear - METs.
Patients were instructed to perform a strict schedule of activities lasting 59 minutes (Table 2) which were chosen to be representative of everyday tasks (such as walking, stair climbing and sweeping the floor) that are reported as problematic by COPD patients [25] (link). Time was kept with both a stopwatch and a laptop computer clock so that activities were completed in whole minutes.
Van Remoortel H., Raste Y., Louvaris Z., Giavedoni S., Burtin C., Langer D., Wilson F., Rabinovich R., Vogiatzis I., Hopkinson N.S, & Troosters T. (2012). Validity of Six Activity Monitors in Chronic Obstructive Pulmonary Disease: A Comparison with Indirect Calorimetry. PLoS ONE, 7(6), e39198.
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Publication 2012
Actigraphy Body Weight Carbon dioxide Chest Chronic Obstructive Airway Disease Cloning Vectors Energy Metabolism Face Fingers Human Body Medical Devices Metabolic Equivalent Oxygen Consumption Oxygen Saturation Patients Rate, Heart Respiratory Rate Tidal Volume
2
Assessing Acute Respiratory Distress Syndrome
We studied mechanically ventilated patients admitted to the emergency departments (EDs) or intensive care units (ICUs) of participating study hospitals, which were part of the NIH Prevention and Early Treatment of Acute Lung Injury (PETAL) Network. We excluded children, pregnant women, and prisoners. At the time a clinical ABG was obtained for a ventilated patient, the nurse or respiratory therapist obtaining the ABG completed a brief case report form (CRF) that included current SpO2, quality of the oximeter waveform, skin pigmentation (graded informally from very light to very dark, on a 5-point ordinal span, with reference skin pigments included on the CRF). Research coordinators then documented age, sex, body mass index (BMI), body temperature (as measured clinically, without preference for core vs. peripheral temperature measurements), ABG results, basic metabolic panel results, hemoglobin, Positive End Expiratory Pressure (PEEP), FIO2, tidal volume, receipt of vasopressors (i.e., epinephrine, norepinephrine, phenylephrine, dopamine, or vasopressin) at the time the ABG was obtained, and whether the patient met consensus criteria for ARDS other than hypoxemia. Specifically, site investigators individually reviewed chest radiographs and the medical record to assess whether ARDS criteria (acute onset of bilateral lung opacities not fully explained by effusions, lobar/lung collapse, or nodules) other than hypoxemia were met. ARDS was then considered present if the PaO2/FIO2 met relevant thresholds. Given resource constraints, we did not require a specific ABG sampling strategy or collect denominator data on the total number of ABGs performed in participating hospitals.
Data were uploaded to the Clinical Coordinating Center (CCC) at Massachusetts General Hospital, where quality analysis and cleaning were undertaken according to standard procedures. Each participating Institutional Review Board (IRB), including the CCC IRB, approved this study with waiver of informed consent on the basis of compliance with 45 CFR 46.116d.
Brown S.M., Duggal A., Hou P.C., Tidswell M., Khan A., Exline M., Park P.K., Schoenfeld D., Liu M., Grissom C.K., Moss M., Rice T.W., Hough C.L., Rivers E., Thompson B.T, & Brower R.G. (2017). Non-linear imputation of PaO2/FIO2 from SpO2/FIO2 among mechanically ventilated patients in the intensive care unit: a prospective, observational study. Critical care medicine, 45(8), 1317-1324.
Publication 2017
Acute Lung Injury Atelectasis Child Dopamine Epinephrine Ethics Committees, Research Hemoglobin Hormone, Antidiuretic Index, Body Mass Light Lung Norepinephrine Nurses Patients Phenylephrine Positive End-Expiratory Pressure Pregnant Women Prisoners Radiography, Thoracic Respiratory Distress Syndrome, Adult Respiratory Rate Saturation of Peripheral Oxygen Skin Pigmentation Tidal Volume Vasoconstrictor Agents
3
Whole-Body Plethysmography for Respiratory Assessment in Mice

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Publication 2014
Cloning Vectors Consciousness Exhaling Humidity Inhalation Mus Plethysmography Plethysmography, Whole Body Pressure Respiratory Rate Tidal Volume
4
ARDS Network Trials Derivation and Validation

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Publication 2020
Placebos Population Group Positive End-Expiratory Pressure Respiratory Distress Syndrome, Acute Rosuvastatin Tidal Volume Tooth Socket
5
Autonomic Modulation Assessment Protocol
Participants were asked to abstain from caffeine-containing food and drink prior to the test and to only consume a light meal 2 h prior to testing. Participant’s skin was cleaned (shaved if necessary) and prepared for the attachment of the ECG electrodes. The electrodes were placed in a CM5 configuration [right fifth interspace, manubrium and left fifth interspace (Dash 2002 )], ensuring that they did not interfere with the fit of the HRM strap (Polar H7). The electrode belt was dampened and placed following Polar’s guidelines, tightly but comfortably just below the chest muscles. Resting measurements were conducted in two positions, supine and, following an active orthostatic challenge, standing in a quiet laboratory, with a temperature of 20.6 ± 1.0 °C. Recordings lasted for 10 min in the supine position and 7 min in standing position. In order to control for the influences of respiration on HRV (Song and Lehrer 2003 (link)) participants matched their breathing frequency to an auditory metronome set at 0.20 Hz (12 breaths min−1). No attempt was made to control the participant’s tidal volume (Pöyhönen et al. 2004 (link)).
Giles D., Draper N, & Neil W. (2015). Validity of the Polar V800 heart rate monitor to measure RR intervals at rest. European Journal of Applied Physiology, 116, 563-571.
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Publication 2015
Caffeine Cell Respiration Food Hearing Light Manubrium Pectoralis Muscles Skin Tidal Volume

Most recents protocols related to «Tidal Volume»

1
Mechanical Ventilation Strategies for Severe Hypoxemia
Among mechanically ventilated patients, TTE was performed in volume-assist control mode, with a target tidal volume (VT) of 6 mL/kg of predicted body weight. In patients with severe hypoxemia (PaO2/FiO2 ratio < 100), PEEP was titrated to avoid exceeding plateau pressure values (Pplat) greater than 30 cm H2O and obtaining a driving pressure less than 15 cm H2O. If Pplat exceeded this maximum threshold, VT was lowered until Pplat was less than 30 cm H2O. On the other hand, to counteract the effect of the reduction in VT on alveolar ventilation, the respiratory rate was increased. Fraction of inspired oxygen (FiO2) was adjusted to obtain a minimum saturation of 92%.
Spontaneously breathing patients who required oxygen were supported with nasal cannula or non-rebreathing mask oxygenator delivering a minimum oxygen flow to achieve SpO2 greater than 92%. Setting primary focus on health-care personnel security, no patient in our ICU received non-invasive mechanical ventilation (e.g. continuous positive airway pressure, non-invasive positive pressure ventilation, or high-flow nasal cannula) due to the risk of aerosol dispersion.11 (link)
Carboni Bisso I., Ruiz V., Falconi M., Baglioni M., Villanueva E., Huespe I., Di Stefano S., Las Heras M, & Sinner J. (2023). Echocardiographic detection of transpulmonary bubble transit during coronavirus-2019 disease (COVID-19). Acta Colombiana de Cuidado Intensivo.
Publication 2023
Body Weight Continuous Positive Airway Pressure Intermittent Positive-Pressure Ventilation Nasal Cannula Noninvasive Ventilation Oxygen Oxygenators Patients Positive End-Expiratory Pressure Pressure Primary Health Care Respiratory Rate Saturation of Peripheral Oxygen Secure resin cement Tidal Volume
2
COVID-19 Pneumonia Barotrauma Outcomes
We conducted a single center, retrospective study with historical controls, of patients with acute hypoxic respiratory failure due to COVID-19 pneumonia who were admitted to the XXX Intensive Care Unit (XXX MICU) between September 30, 2020 to December 31, 2020. Institutional review board approval was obtained from WVU IRB (IRB # 2101205408). The electronic medical record (EMR) and imaging studies (chest x-ray and computed tomography scans) were utilized to identify all patients admitted to the MICU with acute hypoxic respiratory failure and a confirmed SARS-CoV-2 polymerase chain reaction (PCR). The primary outcome of the study was rate of barotrauma (pneumothorax, pneumomediastinum, and/or subcutaneous emphysema) and 30-day mortality in those patients with COVID-19 compared to controls. Secondary outcomes of the study included requirement of mechanical ventilation, ICU and hospital LOS. It is important to note that as per the ICU mechanical ventilation protocol all patients were placed on low tidal volume ventilation (4–6 ml/kg/ body weight) and PEEP was set to keep the driving pressures between 14–18 cm of H2O.
Sharma S., Badami V., Rojas E., Sangani R., Chapman K., Avalon C., King A, & Wen S. (2023). High incidence of barotrauma in patients admitted with COVID-19 to ICU and associated mortality in rural Appalachia: An observational study. PLOS ONE, 18(3), e0282735.
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Publication 2023
Barotrauma Body Weight COVID 19 Hypoxia Mechanical Ventilation Mediastinal Emphysema Patients Pneumonia Pneumothorax Polymerase Chain Reaction Positive End-Expiratory Pressure Radiography, Thoracic Radionuclide Imaging Respiratory Failure SARS-CoV-2 Subcutaneous Emphysema Tidal Volume X-Ray Computed Tomography
3
Rat Anaesthesia and Remifentanil Infusion
Rats were placed in an anaesthesia induction chamber and received isoflurane
anaesthesia (4% in a 1:1 N2O/O2 mixture). After loss of
consciousness, rats were intubated with a 16G cannula and were mechanically
ventilated (75 strokes/min, tidal volume of 4–6 mL). Subsequently, anaesthesia
was maintained using 1.5% isoflurane. A deep level of anaesthesia was verified
by lack of withdrawal reflex to hindpaw pinch. Surgery was performed using
sterilized tools and materials. The jugular vein was exposed and cannulated, and
remifentanil (Ultiva; GlaxoSmithKline, Vienna, Austria), dissolved in 0.9% NaCl,
was given as a bolus injection (30 μg/kg) followed by a 1 h infusion at a rate
of 450 μg/kg/h. Control rats were injected with 0.9% NaCl. Next, cannulation was
removed and the skin was sutured; 15 min later, anaesthesia and mechanical
ventilation were discontinued, and rats were extubated. Behavioural testing
recommenced 4 h after recovery from anaesthesia.
Hogri R., Baltov B., Drdla-Schutting R., Mussetto V., Raphael H., Trofimova L, & Sandkühler J. (2023). Probing pain aversion in rats with the “Heat Escape Threshold” paradigm. Molecular Pain, 19, 17448069231156657.
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Publication 2023
Anesthesia Cannula Cannulation Cerebrovascular Accident Isoflurane Jugular Vein Normal Saline Operative Surgical Procedures Rattus Reflex Skin Tidal Volume Ultiva
4
Respiratory Airflow and Particle Transport
Figure 3 illustrated the details of boundary conditions in this case. The attached breathing zone in front of the cavity was set as zero-gauge pressure inlet to imitate the ambient environment. The outlet of the airway was set as velocity outlet by dividing the physiological volumetric flow rate with the area of the outlet. International Commission on Radiological Protection (ICRP) publication 66 suggests a tidal volume of 0.244 L with a frequency of 39 per minute for children subjects under light exercise condition. Therefore, the equivalent volumetric flow rate of 9.5 litre per minute (LPM) was employed for light exercise condition. Respiratory conditions are determined by human exercise and physical activity. To consider different physiological conditions, numerical simulations under three levels of inhalation flow rates, representing, respectively, resting (3.1 LPM), light exercise (9.5 LPM), heavy exercise (18.9 LPM) circumstances were performed in this study. For the nasal surface as well as surrounding face, it was assumed to be no-slip, stationary and perfect absorbed when predict particle transport.
Sun Q., Dong J., Zhang Y., Tian L, & Tu J. (2023). Numerical modelling of micron particle inhalation in a realistic nasal airway with pediatric adenoid hypertrophy: A virtual comparison between pre- and postoperative models. Frontiers in Pediatrics, 11, 1083699.
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Publication 2023
Child Dental Caries Face Light Nose Physical Conditioning, Human physiology Pressure Radiation Protection Respiration Disorders Respiratory Rate Tidal Volume
5
Anesthetic Management for Thoracic Surgery
All patients received general anesthesia, either alone or in combined with regional nerve block (including paravertebral nerve block, epidural anesthesia, and intercostal nerve block.) according to the type of surgery. Patients underwent lobectomy or sublobectomy according to surgeon’s comprehensive evaluation based on patient’s condition.
Anesthesia induction used propofol and/or etomidate, sufentanil, and rocuronium or cisatracurium. Anesthesia maintenance used sevoflurane or propofol combined with remifentanil or sufentanil. Rocuronium or cisatracurium was used to maintain muscle relaxation. Supplemental drugs such as flurbiprofen axetil were administered when necessary. The aim was to maintain BIS 40-60, blood pressure within 20% of baseline, and temperature 36-37°C.
Double-lumen endotracheal tube of sizes Ch33-39 was used for lung isolation according to patient height. The ventilation mode was volume control mode with 6-8 ml/kg of tidal volume (TV) during two-lung ventilation and 5-6 ml/kg during one-lung ventilation (OLA), and 0-5 cmH2O of positive end-expiratory pressure (PEEP), and 12-20 breaths/min of respiratory rates. The aim was to maintain PETCO2 35-45 mmHg and SpO2 ≥92%. At the end of anesthesia, neostigmine was used to antagonize muscular relaxant before extubation.
Fluid infusion was administrated with crystalloid at a rate of 4–6 mL/kg-1h-1. Colloids or blood product was used according to anesthesiologist’s comprehensive evaluation based on patient’s condition. Patient-controlled intravenous analgesia was used after surgery for postoperative analgesia to maintain numeric rating scales (NRS) ≤ 3 scores.
Jin F., Liu W., Qiao X., Shi J., Xin R, & Jia H.Q. (2023). Nomogram prediction model of postoperative pneumonia in patients with lung cancer: A retrospective cohort study. Frontiers in Oncology, 13, 1114302.
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Publication 2023
Anesthesia Anesthesiologist BLOOD Blood Pressure cisatracurium Colloids Epidural Anesthesia Etomidate flurbiprofen axetil General Anesthesia isolation Lung Management, Pain Muscle Tissue Neostigmine Nerve Block One-Lung Ventilation Operative Surgical Procedures Patient-Controlled Analgesia Patients Pharmaceutical Preparations Positive End-Expiratory Pressure Propofol Relaxations, Muscle Remifentanil Respiratory Rate Rocuronium Saturation of Peripheral Oxygen Sevoflurane Solutions, Crystalloid Sufentanil Surgeons Tidal Volume Tracheal Extubation

Top products related to «Tidal Volume»

1
Flexivent by SCIREQ
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The FlexiVent is a precision lung function testing system developed by SCIREQ. It is designed to measure respiratory mechanics in small laboratory animals, providing researchers with detailed information about lung function. The FlexiVent utilizes forced oscillation techniques to assess parameters such as airway resistance, tissue elastance, and lung volumes. This advanced equipment allows for accurate and reproducible measurements, enabling researchers to gain valuable insights into respiratory physiology and disease models.
2
Flexivent system by SCIREQ
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The FlexiVent system is a precision lung function measurement device. It is designed to assess the mechanical properties of the respiratory system in small laboratory animals. The FlexiVent system uses the forced oscillation technique to provide detailed measurements of lung function parameters.
3
Methacholine by Merck Group
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Methacholine is a laboratory reagent used in various research and diagnostic applications. It functions as a cholinergic agonist, acting on muscarinic acetylcholine receptors. The core function of methacholine is to induce a physiological response, typically used in assessing airway responsiveness.
4
Model 683 by Harvard Apparatus
Sourced in United States
The Model 683 is a syringe pump that is designed for precise fluid delivery in laboratory applications. It features a microprocessor-controlled stepper motor drive and can accommodate a wide range of syringe sizes. The pump can deliver flow rates from 0.001 μL/hr to 220.8 mL/min, with an accuracy of ±0.5%.
5
Matlab by MathWorks
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MATLAB is a high-performance programming language and numerical computing environment used for scientific and engineering calculations, data analysis, and visualization. It provides a comprehensive set of tools for solving complex mathematical and computational problems.
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Servo i by Getinge
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The Servo-i is a ventilator designed for intensive care and anesthesia applications. It provides respiratory support for adult, pediatric, and neonatal patients. The device offers advanced ventilation modes and monitoring capabilities to assist healthcare professionals in delivering effective patient care.
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Rompun is a veterinary drug used as a sedative and analgesic for animals. It contains the active ingredient xylazine hydrochloride. Rompun is designed to induce a state of sedation and pain relief in animals during medical procedures or transportation.
8
Flexivent apparatus by SCIREQ
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The FlexiVent is a small animal ventilator apparatus designed for preclinical research. It is capable of precisely controlling and measuring respiratory mechanics in small laboratory animals such as mice and rats. The FlexiVent provides accurate and reproducible measurements of lung function parameters.
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PowerLab is a data acquisition system designed for recording and analyzing physiological signals. It provides a platform for connecting various sensors and transducers to a computer, allowing researchers and clinicians to capture and analyze biological data.
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Pentobarbital sodium by Merck Group
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Pentobarbital sodium is a laboratory chemical compound. It is a barbiturate drug that acts as a central nervous system depressant. Pentobarbital sodium is commonly used in research and scientific applications.

More about "Tidal Volume"

Tidal Volume: Optimizing Respiratory Measurements for Improved Lung Function Assessment Tidal volume (TV) is a critical parameter in respiratory physiology, referring to the volume of air that moves in and out of the lungs with each normal breath.
Accurate measurement and optimization of tidal volume is crucial in various medical and research applications, such as mechanical ventilation, exercise physiology, and the study of respiratory diseases.
One versatile tool for tidal volume research is the FlexiVent system, which uses the forced oscillation technique to measure respiratory mechanics, including tidal volume.
The FlexiVent apparatus, combined with MATLAB analysis, allows for precise tidal volume measurements and assessment of lung function.
These measurements can be further enhanced by using accessories like the Model 683 ventilator and the Servo-i ventilator, which can precisely control tidal volume and other ventilation parameters.
Medications like Methacholine and Rompun may also be used in respiratory research to induce airway constriction or sedation, respectively, allowing for more controlled tidal volume measurements and lung function testing.
The PowerLab data acquisition system can be integrated with these tools to capture and analyze tidal volume and other respiratory data.
By leveraging advanced technology and AI-driven platforms like PubCompare.ai, researchers can streamline their tidal volume research, easily locate and compare protocols from scientific literature, preprints, and patents, and identify the best practices to enhance reproducibility and accuracy.
This AI-assisted approach to tidal volume optimization empowers researchers to make more informed decisions and drive their studies forward with confidence.
OtherTerms: FlexiVent, FlexiVent system, Methacholine, Model 683, MATLAB, Servo-i, Rompun, FlexiVent apparatus, PowerLab, Pentobarbital sodium