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Visual Acuity

Visual acuity refers to the clearness of vision and the ability to discern fine details.
It is a measure of the sharpness of vision and is typically assessed using an eye chart or other standardized visual tests.
Factors that can influence visual acuity include refractive errors, eye diseases, and aging.
Accurate measurement of visual acuity is crucial for diagnosing and monitoring a variety of eye conditions, as well as for assessing the effectiveness of treatment interventions.
PubCompare.ai offers an innovative tool to enhance visual acuity research by facilitating the identification of optimal protocols and products from the literature, preprints, and patents.
This AI-powered platform can improve reproducibility and accuracy in visual acuity studies, supporting more reliable and insightful findings.

Most cited protocols related to «Visual Acuity»

G*Power 3.1.9.2 (Heinrich-Heine-Universität, Düsseldorf, Germany) was used to determine the sample size. For an effect size of 0.4, an alpha probability of 0.05 and a beta probability of 0.8, the sample size required to detect a statistically significant difference is 20 participants per group. Given the loss of samples, ten additional individuals are required in the two intervention groups. Therefore, 80 participants were recruited from a medical university via advertisements placed in various settings (e.g., canteen, dormitory, and classroom building). During an initial phone and Internet instant message tool screen, the participants were told that the researchers were testing a new computer program designed to help individuals, who were preparing for the following CET-6, reduce test anxiety and develop healthy mental habits; moreover, the entire procedure, including the completion of the psychological scales and collection of saliva and computer behavioral data, would last one week. The Test Anxiety Scale (TAS) was used to assess test anxiety [39 ], and the Depression Anxiety Stress Scales (DASS) were used to assess the individuals’ depression, anxiety and stress states [40 (link)]. According to the CONSORT guidelines, the participants were randomly assigned to three groups (a: ABM group, b: placebo group and c: waiting list group) through the use of a computer-based random assignment program with a 3:3:2 allocation ratio. After the first day when they provided the baseline data, the participants were informed via e-mails regarding their assigned group (A, B or C) and the following programs. WC assigned the participants to an intervention based on a random allocation sequence in opaque, sealed, and stapled envelopes. The participants remained blind to the treatment hypotheses and the content of the other treatment groups. Moreover, the treatment allocation was concealed from the outcome assessor HC. As depicted in Fig. 1, three participants were excluded from the analysis for the following reasons: participant quit halfway through the study (n = 2), and there were too many incorrect responses during the eStroop task (n = 1). Thus, the final sample consisted of 77 undergraduates (57 males, 20 females), aged 18–25 years (M = 21.00, SD = 1.556). All participants were right-handed and reported normal color vision and normal or corrected-to-normal visual acuity.

Flowchart depicting passage of participants

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Publication 2018
Anxiety Base Sequence Females Males NFKBIZ protein, human Placebos Respiratory Diaphragm Saliva Test Anxiety Visual Acuity Visually Impaired Persons
Each participant underwent a complete ophthalmological examination at baseline, which included relevant medical history, blood pressure measurement, best-corrected visual acuity, slitlamp biomicroscopy, gonioscopy, Goldmann applanation tonometry, central corneal thickness measurement, dilated funduscopy, stereoscopic ophthalmoscopy of the optic disc with a 78-diopter lens, and simultaneous stereoscopic disc photography. In addition to photography, the structure of the optic disc and nerve fiber layer was measured with a variety of imaging devices, including the Heidelberg Retina Tomograph (Heidelberg Engineering, Heidelberg, Germany), GDx (Carl Zeiss Meditec, Dublin, California), and optical coherence tomography (Stratus OCT; Carl Zeiss Meditec). Tests of visual function included SAP, short-wavelength automated perimetry, and frequency doubling technology perimetry. See Table 2 for details of the examinations and tests completed at each visit. We tracked all systemic and ocular procedures and medications and any concurrent conditions that might affect vision.
This examination protocol is repeated annually for patients with glaucoma, ocular hypertension, and suspected glaucoma, who receive treatment and glaucoma medications at no cost at the discretion of their glaucoma specialist. Transportation is provided when needed.
All color simultaneous stereophotographs were taken using a Nidek Stereo Camera Model 3-DX (Nidek Inc, Palo Alto, California) after maximal pupil dilation. All photograph evaluations were performed using a simultaneous stereoscopic viewer (Asahi Pentax Stereo Viewer II; Pentax, Tokyo, Japan) with a standard fluorescent light bulb. Certified photograph graders evaluated all photographs. To be certified, individuals were trained and then tested on separate standardized sets of stereophotographs depicting (1) glaucomatous and healthy eyes and (2) progressing and nonprogressing eyes. Recent evidence from the Ocular Hypertension Treatment Study (OHTS) and the European Glaucoma Prevention Study indicated that reproducibility of stereophotograph assessment is good when graders have been trained using this type of formal protocol.16 (link),17 (link)
Each photograph was graded by 2 independent graders according to a standard protocol using the standard photographs as reference. Each grader was masked to the participant’s identity, diagnostic status, study, race, and other results. In cases of disagreement, a third senior grader adjudicated. All photographs were graded for quality and evidence of glaucoma damage. To assess between-grader reproducibility, 80 randomly chosen stereophotographs graded by IDEA (Imaging Data Evaluation and Analysis) Center personnel were evaluated for consensus between 2 graders; 73 of 80 (91%) were assigned the same diagnostic classification of glaucoma or healthy both times. Among the same 80 photographs, IDEA Center graders agreed on a vertical cup-disc ratio within 0.2 mm 70 of 80 times (87%). Adjudication of baseline photos was required in 31% of African descent and 28% of European descent eyes.
Publication 2009
Administration, Ophthalmic Corneal Pachymetry Determination, Blood Pressure Diagnosis Europeans Examination Tables Eye Glaucoma Glaucoma, Suspect Gonioscopy High Blood Pressures Lens, Crystalline Light Medical Devices Medulla Oblongata Mydriasis Negroid Races Nerve Fibers Ocular Hypertension Ophthalmoscopy Optic Disk Patients Perimetry Pharmaceutical Preparations Retina Slit Lamp Examination Tomography Tomography, Optical Coherence Tonometry, Ocular Vision Vision Tests Visual Acuity
CITT-trained and certified optometrists or ophthalmologists using a previously described standardized protocol performed all testing (baseline and masked). An unmasked examiner performed eligibility testing, which included the following: best-corrected visual acuity at distance and near; cover testing at distance and near with objective prism neutralization; near point of convergence; positive and negative fusional vergence at near (fusional convergence and divergence amplitudes); near stereoacuity; monocular accommodative amplitude; and monocular accommodative facility (the ability to quickly achieve clear vision while alternately viewing 20/30 equivalent print through +2 D and −2 D lenses); cycloplegic refraction with 1% cyclopentolate; and an ocular health evaluation. All near testing with at 40cm. A masked examiner administered the CISS.
Major eligibility criteria for the study included best-corrected visual acuity at distance and near of 20/25 or better, no strabismus, heterophoria at near between 2Δ esophoria and 8Δ exophoria, near point of convergence closer than 6.0 cm break, negative fusional vergence at near greater than 7Δ BI-break and 5Δ BI-recovery, positive fusional vergence at near greater than 10Δ BO-break and 7Δ BO-recovery, monocular amplitude of accommodation in diopters greater than 15 minus 25% of the child’s age, and at least 500 seconds of arc of random dot stereopsis on the Randot® Stereotest (Stereo Optical Co, Chicago, IL). A refractive correction was required when the magnitude of uncorrected refractive error or change in refractive error (based on a cycloplegic refraction performed within 2 months) in either eye differed from the current prescription by 0.50 D or more in spherical equivalent of myopia, 1.50D or greater in spherical equivalent of hyperopia, or 0.75 D or greater of astigmatism. Table 1 has the complete listing of eligibility and exclusion criteria.
Publication 2009
Astigmatism Child CISH protein, human Cyclopentolate Cycloplegics Depth Perception Eligibility Determination Esophoria Exophoria Heterophoria Hyperopia Lens, Crystalline Myopia Neoplasm Metastasis Ocular Accommodation Ocular Refraction Ophthalmologists Optometrist prisma Refractive Errors Strabismus Vision Visual Acuity
From February 2008 through December 2009, we enrolled 1208 patients at 44 clinical centers in the United States. Eligibility criteria included an age of 50 years or more, the presence in the study eye (one eye per patient) of previously untreated active choroidal neovascularization due to AMD, and visual acuity between 20/25 and 20/320 on electronic visual-acuity testing.8 (link) To establish the presence of active choroidal neovascularization, we required the presence of leakage, as seen on fluorescein angiography, and of fluid, as seen on time-domain optical coherence tomography (OCT), located either within or below the retina or below the retinal pigment epithelium. Inclusion criteria were neovascularization, fluid, or hemorrhage under the fovea. The study was approved by the institutional review board at each clinical center. All patients provided written informed consent.
Publication 2011
Choroidal Neovascularization Eligibility Determination Ethics Committees, Research Fluorescein Angiography Hemorrhage Pathologic Neovascularization Patients Retina Retinal Pigment Epithelium Tomography, Optical Coherence Vision Visual Acuity
The study was carried out with 82 participants (30 men1) whose mean age was 71.77 years. Seventeen participants were aged between 60 and 69 years, 36 between 70 and 79 years, and 8 between 80 and 89 years. Participants were paid €8 per hour for their participation. All participants were Dutch native speakers with normal or corrected-to-normal vision and only two of them were bilingual speakers. Their visual acuity was tested using a Landolt chart. All participants scored above 1.5 point.
All participants were presented with the tasks in the following order: picture naming, verbal fluency, operation span, and stop-signal task. Their vocabulary was tested in a different session, in the context of another study (Janse and Adank, 2012 (link); Scharenborg and Janse, 2013 (link); Janse and Jesse, 2014 (link)). All participants provided informed consent before the experiment and their data were analyzed anonymously. The educational background of participants was expressed on a scale from 1 (primary school education) to 6 (university education). The average educational level was high school education (Mean = 4; SD = 1.68)2.
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Publication 2014
Multiple Endocrine Neoplasia Type 1 Visual Acuity

Most recents protocols related to «Visual Acuity»

Example 4

FIG. 8 illustrates an exemplary embodiment of the power profile of an optic zone for a lens. The example of FIG. 8 is directed to an ophthalmic lens comprising:

an optic zone comprising:

a primary area 301 having a primary optical power;

a central portion 311;

a first secondary area 302 within the central portion 311 having a first secondary optical power;

a first power transition area 304 having a first power transition from the primary area 301 to the first secondary area 302;

a peripheral portion 310;

a second secondary area 303 within the peripheral portion 310 having a second secondary optical power; and

a second power transition area 305 having a second power transition from the primary area 301 to the second secondary area 303;

wherein the primary optical power is selected according to a prescription for refractive correction, the first secondary optical power is more positive than the primary optical power and the second secondary optical power is more positive than the primary optical power;
wherein the first power transition comprises: at least a first step 306 in the first power transition area 304 in which the rate of change in power, from the first secondary optical power in the first secondary area 302 to the primary optical power in the primary area 301, changes at a first junction 313 between a first transition region 312 within the first power transition 304 and the first step 306 followed by a change in the rate of change in power at a second junction 314 between a second transition region 315 within the first power transition 304 and the first step 306, and
at least a second step 307 and a third step 308,
wherein the second step 307 lies within the second power transition area 305 in which the rate of change in power, from the second secondary optical power in the second secondary area 303 to the primary optical power in the primary area 301, changes at a third junction 318 between a third transition region 319 within the second power transition 305 and the second step 307 followed by a change in the rate of change in power at a fourth junction 317 between a fourth transition region 316 within the second power transition 305 and the second step 307, and the third step 308 lies within the second power transition area 305 in which the rate of change in power, from the second secondary optical power in the second secondary area 303 to the primary optical power in the primary area 301, changes at a fifth junction 321 between a fifth transition region 321 within the second power transition 305 and the third step 308 followed by a change in the rate of change in power at a sixth junction 320 between the third transition region 319 within the second power transition 305 and the third step 308.

In the exemplary embodiment of FIG. 8, the power of the primary area 301 is approximately −2 D and has a progression in optical power progressively increasing in positive power towards the periphery. Such peripheral progressive increase in power may result in effective or improved visual performance or vision performance in one or more aspects of visual performance or vision performance. For example, spherical aberration may be included in the primary area to correct, reduce or manipulate aberration of the eye and ophthalmic lens combined. Such an exemplary inclusion of spherical aberration may improve clarity of vision, contrast, contrast sensitivity, visual acuity, and overall quality of vision or combinations thereof.

In certain embodiments, the power of a primary area may be constant, substantially constant, progressively increasing, progressively decreasing, modulated (i.e. undulating along its power profile), possess an aberration profile (e.g. spherical aberration) or combinations thereof.

In the exemplary embodiment of FIG. 8, the powers of the first step 306, second step 307 and third step 308 are not constant within the steps.

In certain embodiments, the power profile within a step may be constant, or substantially constant, or progressively changing. In certain embodiments in which the power of a step is progressively changing, the change in power across the width of the step may be between 0 and 0.2 D, 0 and 0.15 D or 0 and 0.1 D. In certain embodiments in which two or more steps have progressively changing power profiles, the rate of change of the power profiles between the two or more steps may be equal or unequal.

In the exemplary embodiment of FIG. 8, the power profile along the first power transition 304 and the second power transition 305 are monotonic.

Monotonic means that where a power transition decreases from one area to another area (for example, between a first secondary area and a primary area), the power profile is either decreasing or constant or substantially decreasing or substantially constant along the power transition including steps within the power transition. Conversely, where a power transition increases from one area to another area (for example, from a primary area to a second secondary area), monotonic means the power profile is either increasing or constant or substantially increasing or substantially constant along the power transition including steps within the power transition. In certain embodiments, a power transition will have a monotonic power profile.

In the exemplary embodiment of FIG. 8, changes in the rate of change in optical power at junctions 313 and 314 that forms the first step 306 and changes in the rate of change in optical power at junctions 317 and 318 that forms the second step 307 are less rapid and/or more gradual.

In certain embodiments, a change in the rate of change in optical powers may be considered “gradual” when the change in rate of change occurs over a junction width of between 0.15 and 1 mm, 0.25 and 0.75 mm or 0.3 and 0.5 mm.

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Patent 2024
A-301 Contrast Sensitivity Disease Progression Lens, Crystalline Ocular Refraction Visual Acuity
Not available on PMC !

Example 3

Alternatively or in addition to all of the foregoing as it relates to gray matter, the invention further contemplates that white matter fA (fractional anisotropy) can be employed in a manner analogous to the gray matter atrophy as discussed herein in various embodiments.

Diffusion Tensor Imaging (DTI) assesses white matter, specifically white matter tract integrity. A decrease in fA can occur with either demyelination or with axonal damage or both. One can assess white matter substructures including optic nerve and cervical spinal cord.

MRIs of brain including high cervical spinal cord to be done at month 6, 1 year, and 2 years. If a decrease in fA of 10% is observed in fA of 2 tracts, treat with estriol to halt this decrease. Alternatively if fA is decreased by 10% in only one tract but that tract is associated with clinical deterioration of the disability served by that tract, treat with estriol. Poorer scores in low contrast visual acuity would correlate with decreased fA of optic nerve, while poorer motor function would correlate with decreased fA in motor tracts in cervical spinal cord.

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Patent 2024
Anisotropy Atrophy Axon Brain Clinical Deterioration Copaxone Demyelination Disabled Persons Estriol Gray Matter Magnetic Resonance Imaging Multiple Sclerosis Optic Nerve Spinal Cords, Cervical Visual Acuity White Matter

A robust battery of standardised assessments of cardiovascular function, respiratory function, physical function including hand grip strength, balance, walk speed, visual health, hearing and cognitive health were used, all of which are comparable to those used in other longitudinal studies internationally. Other standard clinical measures including blood pressure, height, weight, and hip and waist circumference were also collected. Non-fasting blood and urine samples were also obtained as part of the health assessment. If glucose or lipid results were outside the normal expected range, then both the participant and participant’s General Practitioner were informed in writing. The assessment methods and their rationale for inclusion in the health assessment are detailed below.
Table 1 provides an overview of the physical, cognitive health, mental health, dietary assessment measures and biological samples measures included in the health assessment and compares the measures to other comparative longitudinal studies of ageing. While many of these measures are described in detail, a comprehensive description of the protocols used is beyond the remit of this article. Further manuscripts detailing specific strands of research being conducted within NICOLA that are not included in this manuscript will be forthcoming including the results from the analysis of the Wave 1 dietary questionnaire.

Measures used in the NICOLA health assessment compared to other similar longitudinal studies of ageing

Outcome MeasureType of assessmentMeasuresComparative study
Physical HealthAnthropometric

Weight

Height

Waist and hip circumference

TILDA, ELSA
Body compositionBodystat (% body fat)None
Cardiovascular

Blood pressure

Orthostatic blood pressure

TILDA, ELSA
RespiratorySpirometryELSA
Mobility and strength

Step test

Timed up and go

Grip strength (dynamometry)

TILDA, ELSA
Vision

Visual acuity

Multi-modal retinal imaging

TILDA (visual acuity)
Facial photographPhysical attractiveness / signs of ageingNone
Cognitive HealthCognitive function

MMSE

MOCA

Colour trails 2

Animal recall

TILDA
Dietary Intake*Food frequency questionnaire

Dietary intake (EPIC-FFQ)

Special diets

Cooking and food shopping

Food supplements / vitamins

ELSA (Wave 9 only, online FFQ (Oxford-WebQ))
Mental Health

Mental well-being

Depression

Warwick-Edinburgh Mental Well-Being Scale (WEMWBS)

Centre for Epidemiologic Studies Depression Scale (CES-D)

None

ELSA

Biological SamplesBlood and urine sample (non-fasting)

Lipid profile

Genomic biomarkers

Dietary biomarkers

Bone markers

Inflammatory markers

Other biomarkers

TILDA, ELSA

* Not detailed in this paper

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Publication 2023
Biopharmaceuticals BLOOD Blood Pressure Body Fat Cardiovascular Physiological Phenomena Cognition Diet Dietary Supplements Eating Face Food Glucose Lipids Physical Examination Respiration Retina TNFSF10 protein, human Urine Visual Acuity Waist Circumference
Participants were recruited from the movement disorder clinic of the Samsung Medical Center. The Institutional Review Board of Samsung Medical Center approved this study, and all subjects provided written informed consent. Patients were enrolled if they were diagnosed with PD based on the United Kingdom Brain Bank Criteria for PD38 (link). Patients with any of the following conditions were excluded: any neurologic disorder other than PD, systemic vasculitis, cardiovascular disease, musculoskeletal disease, end-stage renal disease, peripheral nervous system autonomic failure (diabetic neuropathy, Guillain-Barre syndrome, amyloid neuropathy, surgical sympathectomy, and pheochromocytoma, etc.), ocular pathology that could affect OCTA measurements (glaucoma, a refractive error >+6.0 diopters of spherical equivalent or <−6.0 diopters of spherical equivalent, astigmatism ≥ 3.0 diopters, epiretinal membrane, age-related macular degeneration, diabetic retinopathy, hypertensive retinopathy, retinal artery/vein occlusion, or optic neuropathy) or previous retinal surgery. Exact age- and sex-matched controls were recruited. The healthy controls were required to have normal visual acuity, normal intraocular pressure ≤21 mm Hg, and normal optic discs. The same exclusion criteria were applied to healthy controls and PD patients. Demographic and clinical data, including age, sex, and comorbid vascular risk factors (hypertension, diabetes mellitus, dyslipidemia), were collected for all enrolled participants. The UPDRS III39 (link), H&Y scale40 (link), LEDD41 (link), and MoCA42 (link) were investigated in all enrolled PD patients.
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Publication 2023
Age-Related Macular Degeneration Amyloid Neuropathies Arteries Astigmatism Blood Vessel Brain Cardiovascular Diseases Diabetes Mellitus Diabetic Neuropathies Diabetic Retinopathy Dyslipidemias Epiretinal Membrane Ethics Committees, Research Eye Glaucoma Guillain-Barre Syndrome High Blood Pressures Hypertensive Retinopathy Kidney Failure, Chronic Movement Disorders Musculoskeletal Diseases Nervous System Disorder Neural-Optical Lesion Operative Surgical Procedures Optic Disk Patients Peripheral Nervous System Pheochromocytoma Pure Autonomic Failure Refractive Errors Retina Retinal Artery Occlusion Retinal Vein Occlusion Sympathectomy Tonometry, Ocular Veins Visual Acuity
A subset of the UK Biobank participants completed an eye examination. The measures collected included best corrected visual acuity using a logarithm of the minimum angle of resolution (logMAR) chart (Precision Vision, LaSalle, Illinois, USA). Visual acuity was measured with participants wearing their distance glasses at 4m, or at 1m if a participant was unable to read letters at 4m. Participants were asked to read from the top of the chart downwards, with the test terminated when two or more letters were read incorrectly. Further, refractive error was measured using a Tomey RC-5000 auto refraktometer (Tomey Corp., Nagoya, Japan) [11 (link)]. For each eye, up to 10 measurements were taken and the most reliable measure was automatically recorded. Intraocular pressure (IOP) was measured using an Reichert Ocular response Analyzer [12 (link)] from which corneal compensated IOP was calculated that accounts for rigidity of the cornea [13 (link)].
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Publication 2023
Cornea Eyeglasses Muscle Rigidity Refractive Errors Tonometry, Ocular Vision Visual Acuity

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More about "Visual Acuity"

Visual acuity, a critical measure of eye health and performance, refers to the sharpness and clarity of one's vision.
It's a key indicator of the eye's ability to discern fine details and perceive the world with precision.
Accurate assessment of visual acuity is crucial for diagnosing and monitoring a range of eye conditions, as well as evaluating the effectiveness of various treatment interventions.
Factors that can influence visual acuity include refractive errors, such as nearsightedness (myopia), farsightedness (hyperopia), and astigmatism, as well as the presence of eye diseases like cataracts, glaucoma, and macular degeneration.
Additionally, age-related changes in the eye can also impact visual acuity, making it an important consideration for older adults.
Advancements in ophthalmic technology, such as the IOL Master, Pentacam, Spectralis, IOLMaster 500, Spectralis HRA+OCT, Pentacam HR, IOLMaster 700, Cirrus HD-OCT, and Spectralis OCT, have revolutionized the way visual acuity is measured and monitored.
These cutting-edge instruments provide healthcare professionals with the tools they need to accurately assess visual function and make informed decisions about patient care.
PubCompare.ai, an innovative AI-powered platform, offers a unique solution for enhancing visual acuity research.
By facilitating the identification of optimal protocols and products from the literature, preprints, and patents, this tool can improve the reproducibility and accuracy of visual acuity studies, leading to more reliable and insightful findings.
Researchers and clinicians can leverage this platform to stay on the cutting edge of visual acuity research and ensure the best possible outcomes for their patients.
OtherTerms: Eye health, visual function, refractive errors, eye diseases, ophthalmic technology, visual function assessment, visual acuity measurement, PubCompare.ai, IOL Master, Pentacam, Spectralis, IOLMaster 500, Spectralis HRA+OCT, Pentacam HR, IOLMaster 700, Cirrus HD-OCT, Spectralis OCT, OptoMotry